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Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

Capability on chemical synthesis1. Beijing High-Tech Enterprises2. Strong R&D Team3. 8 years of experiences in R & D of high-tech Catalyst;4. 5000 production techniques, 69 items of national patents, and 360 kinds of products on sales;5. The producti

3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:0

Negotiable

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

3,4-Difluorophenylboronic acid Manufacturer/High quality/Best price/In stock

Cas:168267-41-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3,4-Difloromethylboronic acid supplier in China

Cas:168267-41-2

Min.Order:1 Metric Ton

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Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

Good quality Good price Promptly delivery Appearance:white powder Storage:dry dondition Package:According to the demand of customer Application:intermediate Transportation:According to the demand of customer Port:shanghai

168267-41-2 3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 168267-41-2 3,4-difluorophenylboronic acid Manufacturer

Cas:168267-41-2

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3,4-Difluorobenzeneboronic acid

Cas:168267-41-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/191.html Product Name 3,4-Difluorophenylboronic acid CAS No.

3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

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Leader Biochemical Group

About Product Technical Details Mol File: 168

China Largest factory Manufacturer Supply Highest Quality 3,4-Difluorophenylboronic acid CAS 168267-41-2

Cas:168267-41-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Tianfu Chemical, built in 2009, is a professional supplier for API materials in China. With 10 years development, we have bulit our own factory and lab to produce a certain of products. And we have established stable business relationship

TIANFU CHEM 168267-41-2 3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:1 Kilogram

FOB Price: $200.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 168267-41-2 with competitive price

Cas:168267-41-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

3,4-Difluorophenylboronic acid/ LIDE PHARMA- Factory supply / Best price

Cas:168267-41-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

Name: 2,4,5,6-tetrafluorobenzene-1,3-diol Synonyms: 3,4-Difluorophenylboronic acid CAS:168267-41-2 MF: C6H2F4O2 Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Syntheses Materi

2,4,5,6-tetrafluorobenzene-1,3-diol

Cas:168267-41-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:liquid Storage:Store in sealed containers at cool & dry plac

Supply high purity CAS 168267-41-2 3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3,4-Difluorophenylboronic acid 168267-41-2

Cas:168267-41-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

3,4-Difluorophenylboronic acid CAS:168267-41-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

3,4-Difluorophenylboronic acid CAS:168267-41-2

Cas:168267-41-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

3,4-Difluorophenylboronic Acid

Cas:168267-41-2

Min.Order:0

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Type:Manufacturers

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Kunshan Push Trading Co.,LTD

3,4-difluorophenylboronic acid 168267-41-2 ADVANTAGE 1.Professional: More than 10 years chemical exporting experience. We have produced chemical more than fifteen years, 95% products are for export . More than 10 years chemical exporting experience

3,4-difluorophenylboronic acid 168267-41-2

Cas:168267-41-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

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Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS168267-41-2 3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

3,4-DIFLUOROPHENYLBORONIC ACID

Cas:168267-41-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3,4-difluorophenylboronic acid

Cas:168267-41-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:0 Metric Ton

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Type:Other

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:100 Gram

Negotiable

Type:Other

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 3,4-DifluoroPhenylboronic acid

Cas:168267-41-2

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:Used for Pesticide intermediates Transportati

3,4-Difluorophenylboronic acid

Cas:168267-41-2

Min.Order:1 Gram

Negotiable

Type:Trading Company

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Synthetic route

3,4-difluorophenylmagnesium bromide
90897-92-0

3,4-difluorophenylmagnesium bromide

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

Conditions
ConditionsYield
With Triisopropyl borate In tetrahydrofuran at -40 - 0℃;41%
C6H3BF5(1-)
1033691-65-4

C6H3BF5(1-)

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

Conditions
ConditionsYield
In phosphate buffer pH=6.9 - 7.0; Kinetics;
C14H21BF2O2

C14H21BF2O2

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

Conditions
ConditionsYield
With hydrogenchloride; water In tetrahydrofuran pH=5;
3-bromo-5-methylpyridin-2-amine
17282-00-7

3-bromo-5-methylpyridin-2-amine

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

3-(3,4-difluorophenyl)-5-methylpyridin-2-amine
1340487-51-5

3-(3,4-difluorophenyl)-5-methylpyridin-2-amine

Conditions
ConditionsYield
With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In 1,4-dioxane; water at 100℃; for 1h; Inert atmosphere;100%
With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In 1,4-dioxane; water at 100℃; for 1h; Suzuki Coupling; Inert atmosphere;100%
methyl 2-(4-bromophenyl)-2-pivalamidoacetate

methyl 2-(4-bromophenyl)-2-pivalamidoacetate

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

methyl 2-(3',4'-difluoro-[1,1'-biphenyl]-4-yl)-2-pivalamidoacetate

methyl 2-(3',4'-difluoro-[1,1'-biphenyl]-4-yl)-2-pivalamidoacetate

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In tetrahydrofuran; water at 100℃; for 2h; Suzuki Coupling; Microwave irradiation; Inert atmosphere; Sealed tube;100%
2,2-Dimethyl-1,3-propanediol
126-30-7

2,2-Dimethyl-1,3-propanediol

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

C11H13BF2O2

C11H13BF2O2

Conditions
ConditionsYield
Stage #1: 2,2-Dimethyl-1,3-propanediol; (3,4-difluorophenyl)boronic acid In diethyl ether at 20℃; for 1h;
Stage #2: With calcium chloride at 20℃; for 1h;
100%
4-amino-8-bromo-N-propyl-cinnoline-3-carboxamide
107346-32-7

4-amino-8-bromo-N-propyl-cinnoline-3-carboxamide

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

4-amino-8-(3,4-difluorophenyl)-N-propyl-cinnoline-3-carboxamide

4-amino-8-(3,4-difluorophenyl)-N-propyl-cinnoline-3-carboxamide

Conditions
ConditionsYield
98.7%
para-nitrophenyl bromide
586-78-7

para-nitrophenyl bromide

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

3,4-difluoro-4'-nitro-1,1'-biphenyl
954369-63-2

3,4-difluoro-4'-nitro-1,1'-biphenyl

Conditions
ConditionsYield
With sodium carbonate In water at 25℃; for 6.5h; Suzuki Coupling;98%
With sodium carbonate at 80℃; for 1.16667h; Catalytic behavior; Suzuki Coupling;97%
With sodium carbonate at 100℃; for 0.75h; Suzuki-Miyaura Coupling;95%
1-bromo-4-methoxy-benzene
104-92-7

1-bromo-4-methoxy-benzene

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

3',4'-difluoro-4-methoxy-1,1'-biphenyl

3',4'-difluoro-4-methoxy-1,1'-biphenyl

Conditions
ConditionsYield
With Ph2P(CH2CH2O)22CH3; triethylamine; palladium dichloride In water at 80℃; for 2h; Suzuki coupling; Inert atmosphere;98%
With sodium carbonate at 100℃; for 2.5h; Suzuki-Miyaura Coupling;91%
4-bromobenzenecarbonitrile
623-00-7

4-bromobenzenecarbonitrile

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

3',4'-difluoro-(1,1'-biphenyl)-4-carbonitrile
151559-21-6

3',4'-difluoro-(1,1'-biphenyl)-4-carbonitrile

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,2-dimethoxyethane Suzuki Coupling; Reflux; Inert atmosphere;98%
With sodium carbonate at 80℃; for 1.5h; Catalytic behavior; Suzuki Coupling;97%
With Ph2P(CH2CH2O)22CH3; triethylamine; palladium dichloride In water at 80℃; for 1h; Suzuki coupling; Inert atmosphere;96%
(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

3,3’,4,4’-tetrafluorobiphenyl
136755-64-1

3,3’,4,4’-tetrafluorobiphenyl

Conditions
ConditionsYield
With air In N,N-dimethyl-formamide at 20℃; for 16h; Green chemistry;98%
With copper fluorapatite In methanol at 20℃; for 2h; Green chemistry;93%
With oxygen; potassium carbonate In water at 25℃; for 2h; Green chemistry;93%
4-bromo-6-fluorobenzonitrile
105942-08-3

4-bromo-6-fluorobenzonitrile

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

3,3',4'-trifluoro-[1,1'-biphenyl]-4-carbonitrile

3,3',4'-trifluoro-[1,1'-biphenyl]-4-carbonitrile

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,2-dimethoxyethane Suzuki Coupling; Reflux; Inert atmosphere;98%
4-{3-[6-(3-bromo-5-dimethylcarbamoyl-phenoxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy}-butyric acid ethyl ester
1162261-01-9

4-{3-[6-(3-bromo-5-dimethylcarbamoyl-phenoxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy}-butyric acid ethyl ester

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

4-{3-[6-(5-dimethylcarbamoyl-3',4'-difluoro-biphenyl-3-yloxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy}-butyric acid ethyl ester
1162261-04-2

4-{3-[6-(5-dimethylcarbamoyl-3',4'-difluoro-biphenyl-3-yloxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy}-butyric acid ethyl ester

Conditions
ConditionsYield
With caesium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In 1,2-dimethoxyethane at 97℃; for 15h; Suzuki Coupling;97%
(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

2-(carboxymethyl)-5-iodobenzoic acid

2-(carboxymethyl)-5-iodobenzoic acid

4-(carboxymethyl)-3',4'-difluorobiphenyl-3-carboxylic acid
1354742-83-8

4-(carboxymethyl)-3',4'-difluorobiphenyl-3-carboxylic acid

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; water at 150℃; for 0.5h; Suzuki coupling; Inert atmosphere; Microwave irradiation;97%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; water at 150℃; for 0.5h; Suzuki Coupling; Microwave irradiation;
8-bromo-[1,2,4]triazolo[1,5-a]pyridine-2-ylamine
1124382-72-4

8-bromo-[1,2,4]triazolo[1,5-a]pyridine-2-ylamine

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

8-(3,4-difluoro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
1329672-80-1

8-(3,4-difluoro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine

Conditions
ConditionsYield
With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In 1,4-dioxane; water at 20 - 110℃; for 18h;97%
With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In 1,4-dioxane; water at 110℃; for 18h; Suzuki Coupling;97%
2,6-dibromo-4-nitroaniline
827-94-1

2,6-dibromo-4-nitroaniline

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

2,6-bis(3,4-difluorophenyl)-4-nitroaniline
1426332-53-7

2,6-bis(3,4-difluorophenyl)-4-nitroaniline

Conditions
ConditionsYield
With potassium phosphate tribasic heptahydrate; palladium diacetate In water; N,N-dimethyl-formamide at 80℃; for 0.416667h; Suzuki Coupling;97%
1-bromo-4-(trans-4-pentylcyclohexyl)benzene
79832-89-6

1-bromo-4-(trans-4-pentylcyclohexyl)benzene

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

3,4-difluoro-4'-(4-pentylcyclohexyl)-1,1'-biphenyl
134412-17-2

3,4-difluoro-4'-(4-pentylcyclohexyl)-1,1'-biphenyl

Conditions
ConditionsYield
With 5%-palladium/activated carbon; potassium carbonate In ethanol; water at 80℃; for 0.5h; Suzuki Coupling;97%
8-bromo-N-(2-(methylsulfonyl)ethyl)-1,6-naphthyridine-2-carboxamide
1611473-65-4

8-bromo-N-(2-(methylsulfonyl)ethyl)-1,6-naphthyridine-2-carboxamide

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

8-(3,4-difluorophenyl)-N-(2-(methylsulfonyl)ethyl)-1,6-naphthyridine-2-carboxamide
1611473-16-5

8-(3,4-difluorophenyl)-N-(2-(methylsulfonyl)ethyl)-1,6-naphthyridine-2-carboxamide

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate In 1,4-dioxane; water at 80℃; for 1h;97%
iodobenzene
591-50-4

iodobenzene

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

3,4‐difluoro‐1,1′‐biphenyl
67277-33-2

3,4‐difluoro‐1,1′‐biphenyl

Conditions
ConditionsYield
With sodium carbonate at 100℃; for 0.666667h; Suzuki-Miyaura Coupling;97%
With sodium carbonate at 80℃; for 0.833333h; Catalytic behavior; Suzuki Coupling;97%
With sodium carbonate at 80℃; for 1.41667h; Kinetics; Suzuki Coupling; Green chemistry;96%
7-bromo-N-[(4S)-3,4-dihydro-2H-chromen-4-yl]-3-(dimethylamino)-1-benzothiophene-2-carboxamide

7-bromo-N-[(4S)-3,4-dihydro-2H-chromen-4-yl]-3-(dimethylamino)-1-benzothiophene-2-carboxamide

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

7-(3,4-difluorophenyl)-N-[(4S)-3,4-dihydro-2H-chromen-4-yl]-3-(dimethylamino)-1-benzothiophene-2-carboxamide

7-(3,4-difluorophenyl)-N-[(4S)-3,4-dihydro-2H-chromen-4-yl]-3-(dimethylamino)-1-benzothiophene-2-carboxamide

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,2-dimethoxyethane; water at 100℃; for 1h; Inert atmosphere;97%
4-(4-propylcyclohexyl)-1-bromobenzene
86579-53-5

4-(4-propylcyclohexyl)-1-bromobenzene

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

3',4'-difluoro-4-(4-propylcyclohexyl)-1,1'-biphenyl

3',4'-difluoro-4-(4-propylcyclohexyl)-1,1'-biphenyl

Conditions
ConditionsYield
With potassium phosphate; [Pd(Ph2PCH2CH(CH3)O)2] In tetrahydrofuran; water at 20℃; for 5h; Suzuki cross-coupling reaction;96%
With potassium fluoride; [Ph2P(CH2)2NH2]2PdCl2 In tetrahydrofuran; water at 25 - 27℃; for 5h; Suzuki cross-coupling reaction;96%
With potassium phosphate; cis-bis((diphenylphosphino)acetate-κ2P,O)palladium(II) In tetrahydrofuran at 25 - 27℃; for 5h; Suzuki coupling;91%
4-chloro-8-(2,6-difluorophenyl)-2-{[2-hydroxy-1-(hydroxy-methyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one
911370-10-0

4-chloro-8-(2,6-difluorophenyl)-2-{[2-hydroxy-1-(hydroxy-methyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

4-(3,4-difluoro-phenyl)-8-(2,6-difluoro-phenyl)-2-(2-hydroxy-1-hydroxymethyl-ethylamino)-8H-pyrido[2,3-d]pyrimidin-7-one

4-(3,4-difluoro-phenyl)-8-(2,6-difluoro-phenyl)-2-(2-hydroxy-1-hydroxymethyl-ethylamino)-8H-pyrido[2,3-d]pyrimidin-7-one

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water at 150℃; for 0.25h; Suzuki cross-coupling; Irradiation; microwave;96%
4-Bromothiophen-2-aldehyde
18791-75-8

4-Bromothiophen-2-aldehyde

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

4-(3,4-difluorophenyl)thiophene-2-carbaldehyde
1019780-50-7

4-(3,4-difluorophenyl)thiophene-2-carbaldehyde

Conditions
ConditionsYield
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In ethanol; water; toluene for 16h; Suzuki cross-coupling; Heating;96%
o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

3',4'-difluoro-[1,1'-biphenyl]-2-carbonitrile
1253696-06-8

3',4'-difluoro-[1,1'-biphenyl]-2-carbonitrile

Conditions
ConditionsYield
With 5%-palladium/activated carbon; potassium carbonate In ethanol; water at 80℃; for 0.666667h; Suzuki Coupling;96%
With Ph2P(CH2CH2O)22CH3; triethylamine; palladium dichloride In water at 80℃; for 2h; Suzuki coupling; Inert atmosphere;95%
2,5-diiodo-p-xylene
1124-08-9

2,5-diiodo-p-xylene

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

C20H14F4
1401514-49-5

C20H14F4

Conditions
ConditionsYield
With sodium hydroxide In water for 2h; Reflux;96%
2,6-dibromoaniline
608-30-0

2,6-dibromoaniline

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

2,6-bis(3,4-difluorophenyl)aniline
1426332-55-9

2,6-bis(3,4-difluorophenyl)aniline

Conditions
ConditionsYield
With potassium phosphate tribasic heptahydrate; palladium diacetate In water; N,N-dimethyl-formamide at 80℃; for 1.08333h; Suzuki Coupling;96%
methyl 3-bromo-4-methylbenzoate
104901-43-1

methyl 3-bromo-4-methylbenzoate

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

methyl 3',4'-difluoro-6-methyl-[1,1'-biphenyl]-3-carboxylate

methyl 3',4'-difluoro-6-methyl-[1,1'-biphenyl]-3-carboxylate

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In N,N-dimethyl-formamide at 100℃; for 24h; Inert atmosphere;96%
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In N,N-dimethyl-formamide at 100℃; for 24h; Inert atmosphere;96%
bromobenzene
108-86-1

bromobenzene

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

3,4‐difluoro‐1,1′‐biphenyl
67277-33-2

3,4‐difluoro‐1,1′‐biphenyl

Conditions
ConditionsYield
With sodium carbonate at 80℃; for 1.16667h; Catalytic behavior; Suzuki Coupling;96%
With sodium carbonate at 100℃; for 0.5h; Suzuki-Miyaura Coupling;95%
With sodium carbonate In water at 25℃; for 7h; Suzuki Coupling;91%
4-tolyl iodide
624-31-7

4-tolyl iodide

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

3',4'-difluoro-4-methyl-1,1'-biphenyl

3',4'-difluoro-4-methyl-1,1'-biphenyl

Conditions
ConditionsYield
With sodium carbonate at 80℃; for 1.25h; Catalytic behavior; Suzuki Coupling;96%
With sodium carbonate at 80℃; for 1.5h; Kinetics; Suzuki Coupling; Green chemistry;92%
bromochlorobenzene
106-39-8

bromochlorobenzene

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

C12H7ClF2

C12H7ClF2

Conditions
ConditionsYield
With sodium carbonate at 80℃; for 1.16667h; Kinetics; Suzuki Coupling; Green chemistry;96%
With sodium carbonate at 80℃; for 1.16667h; Catalytic behavior; Suzuki Coupling;87%
2-methoxy-5-bromopyridine
13472-85-0

2-methoxy-5-bromopyridine

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

5-(3,4-difluorophenyl)-2-methoxypyridine

5-(3,4-difluorophenyl)-2-methoxypyridine

Conditions
ConditionsYield
With O4P(3-)*3K(1+)*5H2O; palladium dichloride In water; N,N-dimethyl-formamide at 20℃; for 24h;96%
2-(4-bromophenyl]pyridine
63996-36-1

2-(4-bromophenyl]pyridine

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

2-(3',4'-difluoro-[1,1'-biphenyl]-4-yl)pyridine

2-(3',4'-difluoro-[1,1'-biphenyl]-4-yl)pyridine

Conditions
ConditionsYield
With palladium diacetate; potassium carbonate In ethanol; water at 80℃;95.6%
tert-butyl 2-chloro-3-cyano-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate

tert-butyl 2-chloro-3-cyano-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate

(3,4-difluorophenyl)boronic acid
168267-41-2

(3,4-difluorophenyl)boronic acid

tert-butyl 3-cyano-2-(3,4-difluorophenyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate

tert-butyl 3-cyano-2-(3,4-difluorophenyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate In 1,4-dioxane; water at 110℃; for 12h; Inert atmosphere;95.04%

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