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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

1,2-dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 2369-37-1 with fast shipping

Cas:2369-37-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

1,2-DIBROMO-4-FLUOROBENZENE CAS:2369-37-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organi

1,2-DIBROMO-4-FLUOROBENZENE CAS:2369-37-1

Cas:2369-37-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1,2-DibroMo-4-fluorobenzene

Cas:2369-37-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

1,2-Dibromo-4-fluorobenzene 99%

Cas:2369-37-1

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 1,2-DIBROMO-4-FLUOROBENZENE Synonyms: 3,4-DIBROMOFLUOROBENZENE;1,2-Dibromo-4-fluorobenzene,98%;1,2-Dibromo-4-fluorobenzene 99%;1,2-Dibromo-4-fluorobenzene99%;1,2-DIBROMO-4-FLUOROBENZENE;1,2-DibroMo-4-fluorobenzene[3,4-DibroMofluo

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

1,2-DIBROMO-4-FLUOROBENZENE

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

3,4-Dibromofluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3,4-Dibromofluorobenzene cas no. 2369-37-1 98%

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

1,2-Dibromo-4-Fluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

1,2-DibroMo-4-fluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

1,2-dibromo-4-fluorobenzeneAppearance:detailed see specifications Storage:Keep away of light, cool place Package:25kg/drum;200kg/drum Application:An important raw material and intermediate used in Organic Synthesis, Pharmaceuticals Transportation:Sea

1,2-dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

1,2-DIBROMO-4-FLUOROBENZENEAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

1,2-DIBROMO-4-FLUOROBENZENE

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Pharm intermediate

3,4-Dibromofluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

2369-37-1

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hebei Muhuang Technology Co., Ltd

best seller Application:API

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

1,2-DIBROMO-4-FLUOROBENZENE 2369-37-1

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:White powder Storage:keep sealed and keep from direct light Package:According client's requirements Application:pharmaceutica

1,2-Dibromo-4-Fluorobenzene manufacturer

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

1,2-Dibromo-4-fluorobenzene

Cas:2369-37-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

fluorobenzene
462-06-6

fluorobenzene

1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

Conditions
ConditionsYield
With bromine; iron
3,4-dibromoaniline
615-55-4

3,4-dibromoaniline

1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

Conditions
ConditionsYield
With hydrogenchloride; tetrafluoroboric acid; sodium nitrite Erhitzen des Reaktionsprodukts auf 160grad;
1-Bromo-4-fluorobenzene
460-00-4

1-Bromo-4-fluorobenzene

1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

Conditions
ConditionsYield
With bromine; iron
4-fluoroaniline
371-40-4

4-fluoroaniline

1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

Conditions
ConditionsYield
With tert.-butylnitrite; copper(ll) bromide In acetonitrile
bromine
7726-95-6

bromine

1-Bromo-4-fluorobenzene
460-00-4

1-Bromo-4-fluorobenzene

iron-powder

iron-powder

A

1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

B

2,4-dibromo-1-fluorobenzene
1435-53-6

2,4-dibromo-1-fluorobenzene

fluorobenzene
462-06-6

fluorobenzene

1-1.3 mol bromine

1-1.3 mol bromine

iron-turnings

iron-turnings

A

1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

B

2,4-dibromo-1-fluorobenzene
1435-53-6

2,4-dibromo-1-fluorobenzene

C

1-Bromo-4-fluorobenzene
460-00-4

1-Bromo-4-fluorobenzene

dimethylmonochlorosilane
1066-35-9

dimethylmonochlorosilane

1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

1,2-bis(dimethylsilyl)-4-fluorobenzene

1,2-bis(dimethylsilyl)-4-fluorobenzene

Conditions
ConditionsYield
With magnesium; lithium chloride at 20℃; for 4h;88%
zinc(II) cyanide
557-21-1

zinc(II) cyanide

1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

4-fluorophthalonitrile
65610-14-2

4-fluorophthalonitrile

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tris-(dibenzylideneacetone)dipalladium(0); polymethylhydroxysilane In N,N-dimethyl acetamide at 100℃; for 2h;87%
O-methylresorcine
150-19-6

O-methylresorcine

1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

2-fluoro-7-methoxydibenzo[b,d]furan

2-fluoro-7-methoxydibenzo[b,d]furan

Conditions
ConditionsYield
Stage #1: O-methylresorcine; 1,2,-dibromo-4-fluorobenzene With potassium carbonate; copper(II) oxide In N,N-dimethyl-formamide for 3h; Reflux;
Stage #2: With palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate In N,N-dimethyl-formamide at 130℃; for 12h; Inert atmosphere;
83%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

1-fluoro-3,4-bis(trimethylsilyl)benzene
1265682-42-5

1-fluoro-3,4-bis(trimethylsilyl)benzene

Conditions
ConditionsYield
With magnesium; lithium chloride at 20℃; for 4h;81%
With magnesium; ethylene dibromide In tetrahydrofuran at 20℃; for 0.75h; Inert atmosphere;56%
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

1,2-di(4'-methylphenyl)-4-fluorobenzene
1424360-18-8

1,2-di(4'-methylphenyl)-4-fluorobenzene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In 1,4-dioxane at 90℃; for 8h; Suzuki-Miyaura Coupling; Inert atmosphere;81%
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

phenylboronic acid
98-80-6

phenylboronic acid

1,2-diphenyl-4-fluorobenzene
1424360-17-7

1,2-diphenyl-4-fluorobenzene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In 1,4-dioxane at 90℃; for 8h; Suzuki-Miyaura Coupling; Inert atmosphere;79%
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

9H-carbazole
86-74-8

9H-carbazole

C18H11Br2N

C18H11Br2N

Conditions
ConditionsYield
With calcium hydride; caesium carbonate In N,N-dimethyl-formamide at 130℃; for 18h;75%
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

4-methoxyphenylboronic acid
5720-07-0

4-methoxyphenylboronic acid

1,2-di(4'-methoxyphenyl)-4-fluorobenzene
1424360-20-2

1,2-di(4'-methoxyphenyl)-4-fluorobenzene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In 1,4-dioxane at 90℃; for 8h; Suzuki-Miyaura Coupling; Inert atmosphere;70%
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

2-Methoxyphenylboronic acid
5720-06-9

2-Methoxyphenylboronic acid

1,2-di(2'-methoxyphenyl)-4-fluorobenzene
1424360-19-9

1,2-di(2'-methoxyphenyl)-4-fluorobenzene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In 1,4-dioxane at 90℃; for 8h; Suzuki-Miyaura Coupling; Inert atmosphere;70%
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

1,2-dibromo-4-fluoro-3-iodobenzene
1539314-91-4

1,2-dibromo-4-fluoro-3-iodobenzene

Conditions
ConditionsYield
Stage #1: 1,2,-dibromo-4-fluorobenzene With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.5h;
Stage #2: With iodine In tetrahydrofuran for 0.5h;
70%
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

1-pentanamine
110-58-7

1-pentanamine

molybdenum hexacarbonyl
13939-06-5, 199620-15-0

molybdenum hexacarbonyl

N-pentyl-4-fluorophthalimide
351992-10-4

N-pentyl-4-fluorophthalimide

Conditions
ConditionsYield
With palladium diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; catacxium A In toluene at 100℃; for 16h; Sealed tube; Inert atmosphere;60%
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

(2,3-dimethoxyphenyl)boronic acid
40972-86-9

(2,3-dimethoxyphenyl)boronic acid

1,2-di(2',3'-dimethoxyphenyl)-4-fluorobenzene
1424360-23-5

1,2-di(2',3'-dimethoxyphenyl)-4-fluorobenzene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In 1,4-dioxane at 90℃; for 8h; Suzuki-Miyaura Coupling; Inert atmosphere;59%
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

4-Vinylphenylboronic acid
2156-04-9

4-Vinylphenylboronic acid

1,2-di(4'-vinylphenyl)-4-fluorobenzene
1424360-22-4

1,2-di(4'-vinylphenyl)-4-fluorobenzene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In 1,4-dioxane at 90℃; for 8h; Suzuki-Miyaura Coupling; Inert atmosphere;48%
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

aniline
62-53-3

aniline

4-fluoro-N1,N2-diphenyl-benzene-1,2-diamine

4-fluoro-N1,N2-diphenyl-benzene-1,2-diamine

Conditions
ConditionsYield
With palladium diacetate; tri-tert-butyl phosphine; sodium t-butanolate In toluene at 110℃; for 14h;32%
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

2,6-dimethylaniline
87-62-7

2,6-dimethylaniline

N1,N2-bis-(2,6-dimethyl-phenyl)-4-fluoro-benzene-1,2-diamine

N1,N2-bis-(2,6-dimethyl-phenyl)-4-fluoro-benzene-1,2-diamine

Conditions
ConditionsYield
With palladium diacetate; tri-tert-butyl phosphine; sodium t-butanolate In toluene at 110℃; for 14h;30%
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

2,6-diisopropylbenzenamine
24544-04-5

2,6-diisopropylbenzenamine

N1,N2-bis-(2,6-diisopropyl-phenyl)-4-fluoro-benzene-1,2-diamine

N1,N2-bis-(2,6-diisopropyl-phenyl)-4-fluoro-benzene-1,2-diamine

Conditions
ConditionsYield
With palladium diacetate; tri-tert-butyl phosphine; sodium t-butanolate In toluene at 110℃; for 14h;25%
Trimethyl borate
121-43-7

Trimethyl borate

1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

2,4-dibromo-1-fluorobenzene
1435-53-6

2,4-dibromo-1-fluorobenzene

dihydroxy-(5-bromo-2-fluorophenyl)-borane
112204-57-6

dihydroxy-(5-bromo-2-fluorophenyl)-borane

Conditions
ConditionsYield
With magnesium In tetrahydrofuran; tetrachloromethane; diethyl ether; water; acetic acid
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

A

1-bromo-4-fluoro-2-trimethylsilylbenzene
1265682-43-6

1-bromo-4-fluoro-2-trimethylsilylbenzene

B

2-bromo-4-fluoro-1-trimethylsilylbenzene
1265682-44-7

2-bromo-4-fluoro-1-trimethylsilylbenzene

C

1-fluoro-3,4-bis(trimethylsilyl)benzene
1265682-42-5

1-fluoro-3,4-bis(trimethylsilyl)benzene

Conditions
ConditionsYield
With Rieke-magnesium (MgR) In tetrahydrofuran at 20 - 40℃; for 1.25h; Inert atmosphere;
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

C18H23N3OSi
1607434-42-3

C18H23N3OSi

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C
1.2: 0.5 h
2.1: diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 0.17 h / Sealed tube; Sonication
2.2: 40 h / 40 °C
3.1: tris-(dibenzylideneacetone)dipalladium(0); 1,1'-bis-(diphenylphosphino)ferrocene / N,N-dimethyl acetamide / 26.16 h / 100 °C / Sealed tube; Sonication
4.1: N-ethyl-N,N-diisopropylamine / 1-methyl-pyrrolidin-2-one / 0.33 h / 140 °C / Sealed tube; Microwave irradiation
View Scheme
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

C19H25N3OSi

C19H25N3OSi

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C
1.2: 0.5 h
2.1: diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 0.17 h / Sealed tube; Sonication
2.2: 40 h / 40 °C
3.1: tris-(dibenzylideneacetone)dipalladium(0); 1,1'-bis-(diphenylphosphino)ferrocene / N,N-dimethyl acetamide / 26.16 h / 100 °C / Sealed tube; Sonication
4.1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 18 h / 20 °C / Sealed tube; Inert atmosphere
4.2: 30 h / 60 °C
View Scheme
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

((2,3-dibromo-6-fluorophenyl)ethynyl)trimethylsilane
1539314-93-6

((2,3-dibromo-6-fluorophenyl)ethynyl)trimethylsilane

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C
1.2: 0.5 h
2.1: diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 0.17 h / Sealed tube; Sonication
2.2: 40 h / 40 °C
View Scheme
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

4-fluoro-3-((trimethylsilyl)ethynyl)phthalonitrile
1539314-94-7

4-fluoro-3-((trimethylsilyl)ethynyl)phthalonitrile

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C
1.2: 0.5 h
2.1: diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 0.17 h / Sealed tube; Sonication
2.2: 40 h / 40 °C
3.1: tris-(dibenzylideneacetone)dipalladium(0); 1,1'-bis-(diphenylphosphino)ferrocene / N,N-dimethyl acetamide / 26.16 h / 100 °C / Sealed tube; Sonication
View Scheme
1,2,-dibromo-4-fluorobenzene
2369-37-1

1,2,-dibromo-4-fluorobenzene

(S)-1-(3-hydroxy-3-methylbutan-2-yl)-1H-indole-4,5-dicarbonitrile
1539314-32-3

(S)-1-(3-hydroxy-3-methylbutan-2-yl)-1H-indole-4,5-dicarbonitrile

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C
1.2: 0.5 h
2.1: diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 0.17 h / Sealed tube; Sonication
2.2: 40 h / 40 °C
3.1: tris-(dibenzylideneacetone)dipalladium(0); 1,1'-bis-(diphenylphosphino)ferrocene / N,N-dimethyl acetamide / 26.16 h / 100 °C / Sealed tube; Sonication
4.1: potassium carbonate / 1-methyl-pyrrolidin-2-one / 0.5 h / 60 °C / Sealed tube; Inert atmosphere
4.2: 0.25 h / 140 °C / Microwave irradiation
View Scheme

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