Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:83-13-6
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Cas:83-13-6
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Cas:83-13-6
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inquiryDiethyl phenylmalonate CAS:83-13-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inter
Cas:83-13-6
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Appearance:white powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/Air/Courie
Cas:83-13-6
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Cas:83-13-6
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83-13-6 Diethyl phenylmalonate Appearance:white powder Storage:room temperature Package:according to customers' requirements Application:Pharma intermediates Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect..
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:83-13-6
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Cas:83-13-6
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inquirySuperior quality, moderate price & quick delivery. Appearance:clear colourless to yellowish liquid after melting Storage:Keep away of light,cool place Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Pharmaceutical
Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:83-13-6
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inquiryOur Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an
Product Name: Diethyl phenylmalonate CAS: 83-13-6 MF: C13H16O4 MW: 236.26 EINECS: 201-456-5 Mol File: 83-13-6.mol Diethyl phenylmalonate Structure Diethyl phenylmalonate Chemical Properties Melting point 16 °C (lit.) Boili
Cas:83-13-6
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inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:83-13-6
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Cas:83-13-6
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inquiryConditions | Yield |
---|---|
With barium dihydroxide; sodium tetrachloropalladate(II) In N,N-dimethyl acetamide at 100℃; for 14h; | 100% |
With N,N'-(1R,2R)-cyclohexane-1,2-diyl-bis-[1-(pyridine-2-yl)methanimine]; 3 A molecular sieve; caesium carbonate; copper(l) iodide In acetonitrile at 70℃; for 30h; | 93% |
With copper(l) iodide; caesium carbonate In 1,4-dioxane at 70℃; for 2h; | 93% |
Conditions | Yield |
---|---|
With barium dihydroxide; sodium tetrachloropalladate(II) In N,N-dimethyl acetamide at 100℃; for 14h; | 99% |
With di-tert-butyl(neopentyl)phosphine; sodium hydride; bis(dibenzylideneacetone)-palladium(0) In toluene; mineral oil at 70℃; for 24h; | 89% |
With tri-tert-butyl phosphine; sodium hydride; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran at 70℃; for 1h; | 87% |
Conditions | Yield |
---|---|
With barium dihydroxide; sodium tetrachloropalladate(II) In N,N-dimethyl acetamide at 100℃; for 14h; | 93% |
With potassium phosphate; (1-adamantyl)di(tert-butyl) phosphine; bis(dibenzylideneacetone)-palladium(0) In toluene at 100℃; | 85% |
Conditions | Yield |
---|---|
With polystyrene-trityllithium In tetrahydrofuran Ambient temperature; | 92% |
diethyl (methylsulfonyl)phenylmalonate
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
Stage #1: diethyl phenyl(methylsulfonyl)malonate With 1,4-diaza-bicyclo[2.2.2]octane In toluene at 20℃; for 8h; Reflux; Stage #2: With water | 83% |
With 1,4-diaza-bicyclo[2.2.2]octane; water 1.) toluene, reflux, 2.) room temperature; Yield given. Multistep reaction; |
Conditions | Yield |
---|---|
With trifluorormethanesulfonic acid In neat (no solvent) at 60℃; for 0.5h; Temperature; Friedel-Crafts Alkylation; | 82% |
ethyl 1-imidazolecarboxylate
Ethyl 2-phenylethanoate
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
Stage #1: Ethyl 2-phenylethanoate With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h; Stage #2: ethyl 1-imidazolecarboxylate In tetrahydrofuran at -78 - 20℃; | 81% |
diethyl 2-chloro-2-phenylmalonate
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With zinc In water; acetic acid for 4h; Heating; | 80% |
triphenylbismuth carbonate
diethyl malonate
A
diethyl 2,2-diphenylmalonate
B
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
In tetrahydrofuran at 67℃; for 11h; | A 77% B 18% |
In tetrahydrofuran at 67℃; for 11h; | A 13% B 53% |
1,3-diethyl 2-diazopropanedioate
trimethyl(phenyl)stannane
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With potassium fluoride; [Rh(OH)(cod)]2; XPhos In tetrahydrofuran; water at 70℃; for 1h; Stille Cross Coupling; Heating; Inert atmosphere; | 76% |
1,1,3,3,3-pentafluoro-2-phenylpropene
sodium ethanolate
A
ethyl 3,3,3-trifluoro-2-phenylpropanoate
B
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
In acetonitrile at 25℃; | A 74% B 4% C 4% |
iodobenzene
diethyl malonate
A
Ethyl 2-phenylethanoate
B
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With tri-tert-butyl phosphine; caesium carbonate; tris(dibenzylideneacetone)dipalladium (0) In 1,2-dimethoxyethane at 80℃; for 68h; | A 11% B 71% |
With sodium hydride; copper(l) iodide In 1,4-dioxane at 101℃; for 5h; Title compound not separated from byproducts; | A 3 % Chromat. B 97 % Chromat. |
copper(l) iodide In 1,4-dioxane at 101℃; for 5h; Product distribution; further solvents, catalysts and additives; | A 3 % Chromat. B 97 % Chromat. |
(η6-fluorobenzene)tricarbonylchromium
diethyl malonate
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With potassium hydroxide; iodine In diethyl ether; dimethyl sulfoxide addn. of C6H5CH(COOC2H5)2 to mixt. of Cr(CO)3-complex/powd. KOH in DMSO (stirring; 20°C, 6 h), diln. with aq. HCl, extn. with Et2O, treating with excess I2 (room temp., 3 h); distn. (reduced pressure); identification by GC and NMR; | 66% |
1,3-diethyl 2-diazopropanedioate
phenylboronic acid
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With potassium phosphate; chloro(1,5-cyclooctadiene)rhodium(I) dimer In toluene at 80℃; for 10.5h; Inert atmosphere; Sealed tube; chemoselective reaction; | 63% |
1,3-diethyl 2-diazopropanedioate
phenyl trimethylsiloxane
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With [Rh(OH)(cod)]2; tetrabutyl ammonium fluoride; tricyclohexylphosphine tetrafluoroborate In 1,4-dioxane; water at 100℃; for 5h; Hiyama Coupling; Inert atmosphere; | 62% |
Conditions | Yield |
---|---|
at 170 - 180℃; for 12h; | 61% |
under 20 - 40 Torr; bei der Destillation; |
Conditions | Yield |
---|---|
With lithium tert-butoxide In tetrahydrofuran at 23℃; for 3h; Glovebox; | A 21% B 33% |
diethyl α-bromophenylmalonate
toluene
A
phenyl-p-tolyl-malonic acid diethyl ester
B
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With antimony pentafluoride 1.) SO2, -65 deg C, 2.) -65 deg C to RT; Yield given. Multistep reaction; | A n/a B 28% |
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide at 70℃; for 4h; Phenylation; | 27% |
Conditions | Yield |
---|---|
at 20℃; for 17h; Mechanism; Inert atmosphere; Sealed tube; Photolysis; | A 17% B 18% |
diethyl α-bromophenylmalonate
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With antimony pentafluoride; benzene Product distribution; 1.) SO2, -65 deg C; 2.) -65 deg C to RT; | 13% |
tetrachloromethane
ethyl 2-diazo-3-oxo-3-phenylpropanoate
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
Behandeln des Reaktionsproduktes mit verd. Natriumaethylat-Loesung; |
ethyl 2-diazo-3-oxo-3-phenylpropanoate
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
at 250℃; under 11 Torr; | |
With xylene Behandeln des Reaktionsproduktes mit verd. Natriumaethylat-Loesung; | |
at 250℃; under 11 Torr; |
Conditions | Yield |
---|---|
With sodium ethanolate Erhitzen des Reaktionsprodukts unter 200 Tor auf 140-150grad; |
Conditions | Yield |
---|---|
With sodium ethanolate under 125 Torr; unter Entfernen des entstehenden Aethanols; | |
With sodium hydride In tetrahydrofuran at 0℃; for 4h; Reflux; |
Conditions | Yield |
---|---|
With ammonia; sodium amide Erwaermen des Reaktionsprodukts mit Kohlensaeure-diaethylester in Aether; | |
With diethyl ether; potassium at 20℃; Behandlung des Reaktionsprodukts mit Chlorameisensaeure-aethylester; | |
Multi-step reaction with 2 steps 1: sodium ethanolate 2: 12 h / 170 - 180 °C View Scheme |
Conditions | Yield |
---|---|
With ethanol; sodium at 60℃; man zersetzt das Natriumsalz mit verd. Schwefelsaeure und erhitzt bei etwa 15 mm auf 175grad; |
Conditions | Yield |
---|---|
With hydrogenchloride; ethanol |
Conditions | Yield |
---|---|
With 2-oxo-3-trimethyltetrahydro-1,3-oxazole for 0.25h; Ambient temperature; Yield given; |
ethyl trimethylsilyl ether
Phenylmalonic dibromide
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
In dichloromethane at 15℃; for 15h; Yield given; |
Conditions | Yield |
---|---|
With diisobutylaluminium hydride In tetrahydrofuran for 2h; Mechanism; Product distribution; Ambient temperature; other reducing agents, var. time; | 100% |
With diisobutylaluminium hydride In tetrahydrofuran for 2h; Ambient temperature; | 100% |
Stage #1: diethyl 2-phenylmalonate With sodium hydroxide In tetrahydrofuran; water at 145℃; under 2280.15 Torr; for 0.933333h; Inert atmosphere; Stage #2: With tetrabutyl-ammonium chloride In tetrahydrofuran; water for 0.183333h; Inert atmosphere; Stage #3: With sodium hydroxide In tetrahydrofuran; water; toluene at 156℃; under 3800.26 Torr; for 3.13333h; Solvent; Temperature; Pressure; Inert atmosphere; | 99.6% |
Conditions | Yield |
---|---|
With sodium hydride In mineral oil at 160℃; Inert atmosphere; | 100% |
diethyl 2-phenylmalonate
diethyl α-bromophenylmalonate
Conditions | Yield |
---|---|
With cetyltrimethylammonim bromide; manganese triacetate In acetic acid at 70℃; for 2h; | 99% |
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran Stage #2: With dibromamine-B In tetrahydrofuran; dichloromethane at 0℃; for 1h; | 88% |
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran at 0℃; Stage #2: With N-Bromosuccinimide In tetrahydrofuran for 0.25h; | 63% |
propargyl bromide
diethyl 2-phenylmalonate
diethyl 2-phenyl-2-(prop-2-yn-1-yl)malonate
Conditions | Yield |
---|---|
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h; Stage #2: propargyl bromide In tetrahydrofuran; toluene; mineral oil at 0 - 20℃; | 99% |
(i) NaOEt, EtOH, (ii) /BRN= 605309/; Multistep reaction; |
diethyl 2-phenylmalonate
α-Amino-α-phenyl-malonsaeure-diaethylester
Conditions | Yield |
---|---|
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran at 23℃; for 0.25h; Stage #2: With O-(4-nitrobenzoyl) hydroxylamine In tetrahydrofuran at 23℃; | 99% |
With sodium hydride; O-(2,4-dinitrophenyl)hydroxylamine | |
(i) NaH, THF, (ii) O-(2,4-dinitro-phenyl)-hydroxylamine; Multistep reaction; |
diethyl 2-phenylmalonate
(4-methylphenyl)methyl carbonate
Conditions | Yield |
---|---|
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃; | 99% |
With 1,1'-bis-(diphenylphosphino)ferrocene; N,O-bis-(trimethylsilyl)-acetamide; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; potassium acetate In tetrahydrofuran at 80℃; for 24h; | 98% |
diethyl 2-phenylmalonate
(4-methoxyphenyl)methyl methyl carbonate
diethyl [(4-methoxyphenyl)methyl](phenyl)malonate
Conditions | Yield |
---|---|
With 1,1'-bis(diisopropylphosphino)ferrocene; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; caesium carbonate In N,N-dimethyl-formamide at 30℃; for 24h; Inert atmosphere; | 99% |
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃; for 3h; | 98% |
With 1,1'-bis-(diphenylphosphino)ferrocene; N,O-bis-(trimethylsilyl)-acetamide; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; potassium acetate In tetrahydrofuran at 80℃; for 4h; | 94% |
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃; | 99% |
With 1,1'-bis-(diphenylphosphino)ferrocene; N,O-bis-(trimethylsilyl)-acetamide; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; potassium acetate In tetrahydrofuran at 80℃; for 24h; | 86% |
With 1,1'-bis(diisopropylphosphino)ferrocene; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; caesium carbonate In N,N-dimethyl-formamide at 30℃; for 4h; Inert atmosphere; | 84% |
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With 1,1'-bis-(diphenylphosphino)ferrocene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃; for 1h; | 99% |
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With 1,1'-bis-(diphenylphosphino)ferrocene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃; for 1h; | 99% |
Conditions | Yield |
---|---|
With bis(η3-allyl-μ-chloropalladium(II)); C24H31O2P; lithium acetate; bis-(trimethylsilyl)acetamide In dichloromethane at -20℃; for 10h; Inert atmosphere; optical yield given as %ee; | 99% |
<2H9>trimethylsulphoxonium iodide
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h; Sealed tube; Stage #2: <2H9>trimethylsulphoxonium iodide In tetrahydrofuran; mineral oil at 80℃; for 8h; Sealed tube; | 99% |
Conditions | Yield |
---|---|
Stage #1: diethyl 2-phenylmalonate With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.166667h; Stage #2: methyl iodide In N,N-dimethyl-formamide for 18h; | 98% |
With sodium ethanolate In ethanol for 3h; Heating; | 81% |
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h; Inert atmosphere; Schlenk technique; Stage #2: methyl iodide In tetrahydrofuran; mineral oil at 0 - 20℃; for 36h; Inert atmosphere; Schlenk technique; | 75% |
benzyl methyl carbonate
diethyl 2-phenylmalonate
diethyl 2-benzyl-2-phenylmalonate
Conditions | Yield |
---|---|
With 1,1'-bis(diisopropylphosphino)ferrocene; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; caesium carbonate In N,N-dimethyl-formamide at 30℃; for 48h; Inert atmosphere; | 98% |
With 1,1'-bis-(diphenylphosphino)ferrocene; N,O-bis-(trimethylsilyl)-acetamide; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; potassium acetate In tetrahydrofuran at 80℃; for 24h; | 95% |
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃; | 84% |
diethyl 2-phenylmalonate
hydroxyphenylmalonic acid diethyl ester
Conditions | Yield |
---|---|
With 10% Pd on charcoal; oxygen; triethylamine In ethanol at 20℃; for 6h; | 98% |
With 5%-palladium/activated carbon; triethylamine In ethanol at 20℃; for 5h; Reagent/catalyst; | 98% |
With Pd2hpp4; 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; oxygen In tetrahydrofuran at 6℃; under 760.051 Torr; for 12h; regioselective reaction; | 97% |
With iodine; sodium acetate In tetrahydrofuran; water at 35℃; for 5h; Irradiation; Green chemistry; | 88% |
diethyl 2-phenylmalonate
ethyl 2-(hydroxyimino)-2-phenylacetate
Conditions | Yield |
---|---|
With sulfuric acid; potassium carbonate; sodium nitrite In ethanol; water at 10℃; for 5h; | 97.2% |
trans-geranyl bromide
diethyl 2-phenylmalonate
(E)-diethyl 2-[3,7-dimethylocta-2,6-dienyl]-2-phenylmalonate
Conditions | Yield |
---|---|
With sodium hydride In tetrahydrofuran at 20℃; for 0.0833333h; Inert atmosphere; | 97% |
With sodium ethanolate In ethanol |
4-methoxy-aniline
diethyl 2-phenylmalonate
4-hydroxy-6-methoxy-3-phenyl-2(1H)-quinolinone
Conditions | Yield |
---|---|
In diphenylether at 250 - 300℃; for 3h; | 97% |
71% | |
at 260 - 270℃; | 71% |
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With 1,1'-bis(diisopropylphosphino)ferrocene; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; caesium carbonate In N,N-dimethyl-formamide at 50℃; for 24h; Inert atmosphere; | 97% |
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃; | 90% |
rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With N,O-bis-(trimethylsilyl)-acetamide; bis(η3-allyl-μ-chloropalladium(II)); N-[(S)-1-(2-(diphenylphosphino)phenyl)ethyl]-1,7,7-trimethylbicyclo[2,2,1]heptan-2-imine; cesium acetate In toluene at 20℃; enantioselective reaction; | 97% |
With N,O-bis-(trimethylsilyl)-acetamide; bis(η3-allyl-μ-chloropalladium(II)); (S)-7-(diphenylphosphino)-2′-isopropyl-2,3-dihydro-5′H-spiro[indene-1,4′-oxazole]; potassium acetate In toluene at 0℃; for 5h; Inert atmosphere; Schlenk technique; enantioselective reaction; | 91% |
Conditions | Yield |
---|---|
Stage #1: diethyl 2-phenylmalonate With lithium tert-butoxide In acetonitrile at 20℃; for 0.166667h; Stage #2: C12H10(2)HF2NO6S In acetonitrile at 20℃; for 0.166667h; | 97% |
diethyl 2-phenylmalonate
Conditions | Yield |
---|---|
With 2-Picolinic acid; bis[dichloro(pentamethylcyclopentadienyl)ruthenium(III)]; caesium carbonate In acetonitrile at 60℃; for 18h; Inert atmosphere; | 97% |
2-(2-bromoethoxy)tetrahydropyran
diethyl 2-phenylmalonate
(tetrahydropyrannyl-2 oxy)-2 ethyl phenyl malonate de diethyle
Conditions | Yield |
---|---|
With hydrogenchloride In N,N-dimethyl-formamide | 96% |
With potassium tert-butylate 1.) t-butanol, 70 deg. C, 2 h; 2.) 70 deg C, 10 h; Yield given. Multistep reaction; |
diethyl 2-phenylmalonate
Diethyl [α-2H]phenylmalonate
Conditions | Yield |
---|---|
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran for 5h; Metallation; Heating; Stage #2: With diclazuril; water-d2 Substitution; Deuteration; Further stages.; | 96% |
diethyl 2-phenylmalonate
[(4-trifluoromethyl)phenyl]methyl methyl carbonate
Conditions | Yield |
---|---|
With 1,1'-bis(diisopropylphosphino)ferrocene; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; caesium carbonate In N,N-dimethyl-formamide at 30℃; for 24h; Inert atmosphere; | 96% |
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃; | 90% |
With 1,1'-bis-(diphenylphosphino)ferrocene; N,O-bis-(trimethylsilyl)-acetamide; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; potassium acetate In tetrahydrofuran at 80℃; for 48h; | 78% |
Conditions | Yield |
---|---|
In diphenylether Heating; | 96% |
diethyl 2-phenylmalonate
3-amino-4,6-dimethylpyrazolo[3,4-b]pyridine
4-hydroxy-8,10-dimethyl-3-phenylpyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidin-2(1H)-one
Conditions | Yield |
---|---|
In diphenylether at 220 - 250℃; | 96% |
(Z)-3-bromo-5-triisopropylsilyl-1,3-pentadiene
diethyl 2-phenylmalonate
diethyl 2-phenyl-2-[5-(triisopropylsilyl)penta-2,3-dienyl]propane-1,3-dioate
Conditions | Yield |
---|---|
With (PdAllylCl)2; sodium hydride; 2,2'-bis(diphenylphosphino)biphenyl In tetrahydrofuran at 23℃; for 12h; Inert atmosphere; | 96% |
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