Product Name

  • Name

    2-BROMO-3,3,3-TRIFLUOROPROPENE

  • EINECS -0
  • CAS No. 1514-82-5
  • Article Data15
  • CAS DataBase
  • Density 1.686
  • Solubility Soluble in most organic solvents, immiscible with water.
  • Melting Point
  • Formula C3H2BrF3
  • Boiling Point 29-30 °C(lit.)
  • Molecular Weight 174.948
  • Flash Point ~10 °F
  • Transport Information UN 1993 3
  • Appearance liquid
  • Safety S24; S36
  • Risk Codes R12; R66
  • Molecular Structure Molecular Structure of 1514-82-5 (2-BROMO-3,3,3-TRIFLUOROPROPENE)
  • Hazard Symbols HighlyF+ FlammableF IrritantXi
  • Synonyms 2-Bromo-3,3,3-trifluoro-1-propene;2-Bromo-3,3,3-trifluoropropene;3,3,3-Trifluoro-2-bromopropene;Halon 1323;Propene,2-bromo-3,3,3-trifluoro- (6CI,8CI);
  • PSA 0.00000
  • LogP 2.45730

Synthetic route

1,2-Dibromo-3,3,3-trifluoropropane
431-21-0

1,2-Dibromo-3,3,3-trifluoropropane

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

Conditions
ConditionsYield
With potassium hydroxide93%
With potassium hydroxide In ethanol at -10℃;91%
With Aliquat 336; sodium hydroxide at 50 - 70℃;80.46%
2,3-dibromo-3,3-difluoro-propene
677-35-0

2,3-dibromo-3,3-difluoro-propene

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

Conditions
ConditionsYield
With antimonypentachloride; antimony(III) fluoride
3-acetoxy-2-bromo-1,1,1-trifluoropropane
383-68-6

3-acetoxy-2-bromo-1,1,1-trifluoropropane

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

Conditions
ConditionsYield
With potassium hydroxide
(2-bromo-3,3,3-trifluoro-propyl)-bis-trifluoromethyl-amine
19451-92-4

(2-bromo-3,3,3-trifluoro-propyl)-bis-trifluoromethyl-amine

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

Conditions
ConditionsYield
With potassium hydroxide
2-bromo-3-chloro-3,3-difluoro-propene
421-44-3

2-bromo-3-chloro-3,3-difluoro-propene

antimony(III) fluoride
7783-56-4

antimony(III) fluoride

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

antimony dichloride trifluoride

antimony dichloride trifluoride

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

2-bromo-3,3,3-trichloro-propene
28124-18-7

2-bromo-3,3,3-trichloro-propene

antimony(III) fluoride
7783-56-4

antimony(III) fluoride

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

antimony dichloride trifluoride

antimony dichloride trifluoride

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

1,2-Dibromo-3,3,3-trifluoropropane
431-21-0

1,2-Dibromo-3,3,3-trifluoropropane

ethanolic KOH-solution

ethanolic KOH-solution

A

3,3,3-trifluoroprop-1-yne
661-54-1

3,3,3-trifluoroprop-1-yne

B

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

Conditions
ConditionsYield
at -5℃;
1,2-Dibromo-3,3,3-trifluoropropane
431-21-0

1,2-Dibromo-3,3,3-trifluoropropane

potassium hydroxide

potassium hydroxide

A

3,3,3-trifluoroprop-1-yne
661-54-1

3,3,3-trifluoroprop-1-yne

B

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

3-acetoxy-2-bromo-1,1,1-trifluoropropane
383-68-6

3-acetoxy-2-bromo-1,1,1-trifluoropropane

A

1,1,1-trifluoro-2,3-epoxypropane
359-41-1

1,1,1-trifluoro-2,3-epoxypropane

B

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

Conditions
ConditionsYield
With sodium hydroxide In water at 100℃; Title compound not separated from byproducts.;
2-bromo-1,1,1-trifluoropropan-3-ol
311-86-4

2-bromo-1,1,1-trifluoropropan-3-ol

A

1,1,1-trifluoro-2,3-epoxypropane
359-41-1

1,1,1-trifluoro-2,3-epoxypropane

B

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

Conditions
ConditionsYield
With sodium hydroxide In water at 0 - 95℃;
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

cyclohexanecarbaldehyde
2043-61-0

cyclohexanecarbaldehyde

1-Cyclohexyl-4,4,4-trifluoro-2-butyn-1-ol
95540-90-2

1-Cyclohexyl-4,4,4-trifluoro-2-butyn-1-ol

Conditions
ConditionsYield
Stage #1: 2-bromo-3,3,3-trifluoropropene With n-butyllithium; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; hexane at -78℃; for 0.333333h; Inert atmosphere;
Stage #2: cyclohexanecarbaldehyde In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
100%
With lithium diisopropyl amide In tetrahydrofuran 1.) -78 deg C, 5 min, 2.) 30 min;93.3%
With lithium diisopropyl amide In tetrahydrofuran; cyclohexane 1.) -78 deg C, 10 min, 2.) -78 deg C, 1 h;90%
heptanal
111-71-7

heptanal

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

1,1,1-trifluoro-2-decyn-4-ol
94792-94-6

1,1,1-trifluoro-2-decyn-4-ol

Conditions
ConditionsYield
Stage #1: 2-bromo-3,3,3-trifluoropropene With n-butyllithium; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; hexane at -78℃; for 0.333333h; Inert atmosphere;
Stage #2: heptanal In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
100%
With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.5h;90%
With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 3h;
(E)-3-phenylpropenal
14371-10-9

(E)-3-phenylpropenal

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

(E)-6,6,6-Trifluoro-1-phenyl-1-hexen-4-yn-3-ol
171668-24-9

(E)-6,6,6-Trifluoro-1-phenyl-1-hexen-4-yn-3-ol

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran 1.) -78 deg C, 5 min, 2.) 30 min;99%
3-phenyl-propionaldehyde
104-53-0

3-phenyl-propionaldehyde

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

6,6,6-Trifluoro-1-phenyl-4-hexyn-3-ol
94792-93-5

6,6,6-Trifluoro-1-phenyl-4-hexyn-3-ol

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran 1.) -78 deg C, 5 min, 2.) 30 min;99%
With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.5h;99%
Stage #1: 2-bromo-3,3,3-trifluoropropene With lithium diisopropyl amide In tetrahydrofuran; hexane at -80℃; for 0.0833333h;
Stage #2: 3-phenyl-propionaldehyde In tetrahydrofuran; hexane at -80℃; for 1.5h;
89%
Stage #1: 2-bromo-3,3,3-trifluoropropene With n-butyllithium; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; hexane at -78℃; for 0.333333h; Inert atmosphere;
Stage #2: 3-phenyl-propionaldehyde In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
80%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

cyclohexanone
108-94-1

cyclohexanone

1-(3,3,3-trifluoro-1-propynyl)-1-cyclohexanol
96302-93-1

1-(3,3,3-trifluoro-1-propynyl)-1-cyclohexanol

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran 1.) -78 deg C, 5 min, 2.) 30 min;99%
Stage #1: 2-bromo-3,3,3-trifluoropropene With n-butyllithium; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; hexane at -78℃; for 0.333333h; Inert atmosphere;
Stage #2: cyclohexanone In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
96%
Stage #1: 2-bromo-3,3,3-trifluoropropene With lithium diisopropyl amide In tetrahydrofuran; hexane; cyclohexane at -78 - 20℃;
Stage #2: cyclohexanone In tetrahydrofuran; hexane; cyclohexane at -78℃; for 1h;
94%
Stage #1: 2-bromo-3,3,3-trifluoropropene With lithium hexamethyldisilazane In tetrahydrofuran at -78 - 0℃;
Stage #2: cyclohexanone In tetrahydrofuran at 0℃;
90%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

4-tolyl iodide
624-31-7

4-tolyl iodide

1-(p-methylphenyl)-3,3,3-trifluoropropyne
82203-82-5

1-(p-methylphenyl)-3,3,3-trifluoropropyne

Conditions
ConditionsYield
Stage #1: 2-bromo-3,3,3-trifluoropropene With dichloro(N,N,N’,N‘-tetramethylethylenediamine)zinc; lithium diisopropyl amide In tetrahydrofuran; hexane at -78 - 20℃; for 1h;
Stage #2: 4-tolyl iodide With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; hexane for 6h; Heating;
99%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

para-iodoanisole
696-62-8

para-iodoanisole

1-(p-methoxyphenyl)-3,3,3-trifluoropropyne
82203-83-6

1-(p-methoxyphenyl)-3,3,3-trifluoropropyne

Conditions
ConditionsYield
Stage #1: 2-bromo-3,3,3-trifluoropropene With dichloro(N,N,N’,N‘-tetramethylethylenediamine)zinc; lithium diisopropyl amide In tetrahydrofuran; hexane at -78 - 20℃; for 1h;
Stage #2: para-iodoanisole With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; hexane for 6h; Heating;
99%
2-Ethylbutyraldehyde
97-96-1

2-Ethylbutyraldehyde

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

5-ethyl-1,1,1-trifluoro-2-heptyn-4-ol
1147879-99-9

5-ethyl-1,1,1-trifluoro-2-heptyn-4-ol

Conditions
ConditionsYield
Stage #1: 2-bromo-3,3,3-trifluoropropene With n-butyllithium; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; hexane at -78℃; for 0.333333h; Inert atmosphere;
Stage #2: 2-Ethylbutyraldehyde In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
99%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

benzaldehyde
100-52-7

benzaldehyde

1-phenyl-4,4,4-trifluorobut-2-yn-1-ol
149846-93-5, 128746-89-4

1-phenyl-4,4,4-trifluorobut-2-yn-1-ol

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran 1.) -78 deg C, 5 min, 2.) 30 min;98.9%
With lithium diisopropyl amide In tetrahydrofuran; cyclohexane 1.) -78 deg C, 10 min, 2.) -78 deg C, 1 h;95%
Stage #1: 2-bromo-3,3,3-trifluoropropene With lithium diisopropyl amide In tetrahydrofuran; hexane; cyclohexane at -78 - 20℃;
Stage #2: benzaldehyde In tetrahydrofuran; hexane; cyclohexane at -78℃; for 1h;
93%
benzophenone
119-61-9

benzophenone

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

1,1-Diphenyl-4,4,4-trifluorobut-2-yn-1-ol
186143-62-4

1,1-Diphenyl-4,4,4-trifluorobut-2-yn-1-ol

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran; cyclohexane 1.) -78 deg C, 10 min, 2.) -78 deg C, 1 h;98%
Stage #1: 2-bromo-3,3,3-trifluoropropene With lithium diisopropyl amide In tetrahydrofuran; hexane; cyclohexane at -78 - 20℃;
Stage #2: benzophenone In tetrahydrofuran; hexane; cyclohexane at -78℃; for 1h;
94%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

tridecanal
10486-19-8

tridecanal

1,1,1-trifluoro-2-hexadecyn-4-ol

1,1,1-trifluoro-2-hexadecyn-4-ol

Conditions
ConditionsYield
Stage #1: 2-bromo-3,3,3-trifluoropropene With lithium diisopropyl amide In tetrahydrofuran; hexane at -80℃; for 0.0833333h;
Stage #2: tridecanal In tetrahydrofuran; hexane at -80℃; for 1.5h;
98%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

N-phenylbenzohydrazonoyl chloride
15424-14-3

N-phenylbenzohydrazonoyl chloride

1,3-diphenyl-5-(trifluoromethyl)-1H-pyrazole

1,3-diphenyl-5-(trifluoromethyl)-1H-pyrazole

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane In 5,5-dimethyl-1,3-cyclohexadiene at 20℃; for 24h; Reagent/catalyst; Solvent; regioselective reaction;98%
With 1,4-diaza-bicyclo[2.2.2]octane In 5,5-dimethyl-1,3-cyclohexadiene at 20℃; for 24h; Reagent/catalyst; Solvent;98%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

(3,5-dichlorophenyl)boronic acid
67492-50-6

(3,5-dichlorophenyl)boronic acid

1,3-dichloro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzene
864725-22-4

1,3-dichloro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzene

Conditions
ConditionsYield
With potassium carbonate; (1,4-naphthoquinone)-[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]palladium(0) In 1,4-dioxane; water at 90℃; for 5h; Product distribution / selectivity; Inert atmosphere;97.8%
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate In tetrahydrofuran; water at 70℃; for 4h; Sealed tube;85%
With potassium carbonate; bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran; water at 0 - 90℃; for 6h; Sealed tube;83%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

N-benzylidenebenzamide
10374-29-5

N-benzylidenebenzamide

N-[1-phenyl-2-(trifluoromethyl)prop-2-ene-1-yl]benzamide

N-[1-phenyl-2-(trifluoromethyl)prop-2-ene-1-yl]benzamide

Conditions
ConditionsYield
Stage #1: 2-bromo-3,3,3-trifluoropropene With sec.-butyllithium In diethyl ether; cyclohexane at -105℃; for 0.166667h;
Stage #2: N-benzylidenebenzamide In diethyl ether; cyclohexane at -105 - -50℃; for 2h;
97%
Stage #1: 2-bromo-3,3,3-trifluoropropene; N-benzylidenebenzamide With sec.-butyllithium In diethyl ether; cyclohexane at -105℃; for 0.166667h; Inert atmosphere;
Stage #2: With boron trifluoride diethyl etherate In diethyl ether; cyclohexane at -105 - -50℃; for 2h; Inert atmosphere;
Stage #3: With water In diethyl ether; cyclohexane pH=7; aq. phosphate buffer;
97%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

2-Phenylpropanal
34713-70-7

2-Phenylpropanal

6,6,6-Trifluoro-2-phenyl-4-hexyn-3-ol

6,6,6-Trifluoro-2-phenyl-4-hexyn-3-ol

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran 1.) -78 deg C, 5 min, 2.) 30 min;96.5%
iodobenzene
591-50-4

iodobenzene

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

3,3,3-trifluoro-2-phenylpropene
384-64-5

3,3,3-trifluoro-2-phenylpropene

Conditions
ConditionsYield
With chloro-trimethyl-silane; N,N,N,N,-tetramethylethylenediamine; silver; zinc In tetrahydrofuran multistep reaction; other aryl halides;96%
With chloro-trimethyl-silane; N,N,N,N,-tetramethylethylenediamine; silver; zinc; tetrakis(triphenylphosphine) palladium(0) 1) THF, 60 deg C, 9 h, 2) 45 deg C, 6 h; Yield given. Multistep reaction;
methanol
67-56-1

methanol

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

(Z)-1-Methoxy-3,3,3-trifluoroprop-1-ene
26885-67-6

(Z)-1-Methoxy-3,3,3-trifluoroprop-1-ene

Conditions
ConditionsYield
With potassium hydroxide for 1h;96%
ethanol
64-17-5

ethanol

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

(Z)-1-ethoxy-3,3,3-trifluoroprop-1-ene
126015-28-9

(Z)-1-ethoxy-3,3,3-trifluoroprop-1-ene

Conditions
ConditionsYield
With potassium hydroxide for 1h;96%
With potassium hydroxide for 1h;95%
Stage #1: 2-bromo-3,3,3-trifluoropropene With potassium hydroxide In water
Stage #2: ethanol In water
95%
d,l-2-ethylhexanal
123-05-7

d,l-2-ethylhexanal

2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

5-Ethyl-1,1,1-trifluoronon-2-yn-4-ol

5-Ethyl-1,1,1-trifluoronon-2-yn-4-ol

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran; cyclohexane 1.) -78 deg C, 10 min, 2.) -78 deg C, 1 h;96%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

N-(2,2-dimethylpropylidene)-p-toluenesulfonamide
135822-92-3

N-(2,2-dimethylpropylidene)-p-toluenesulfonamide

4-methyl-N-[4,4-dimethyl-2-(trifluoromethyl)pent-1-en-3-yl]benzenesulfonamide

4-methyl-N-[4,4-dimethyl-2-(trifluoromethyl)pent-1-en-3-yl]benzenesulfonamide

Conditions
ConditionsYield
Stage #1: 2-bromo-3,3,3-trifluoropropene With sec.-butyllithium In diethyl ether; cyclohexane at -105℃; for 0.166667h;
Stage #2: N-(2,2-dimethylpropylidene)-p-toluenesulfonamide In diethyl ether; cyclohexane at -105 - -50℃; for 2h;
96%
Stage #1: 2-bromo-3,3,3-trifluoropropene; N-(2,2-dimethylpropylidene)-p-toluenesulfonamide With sec.-butyllithium In diethyl ether; cyclohexane at -105℃; for 0.166667h; Inert atmosphere;
Stage #2: With boron trifluoride diethyl etherate In diethyl ether; cyclohexane at -105 - -50℃; for 2h; Inert atmosphere;
Stage #3: With water In diethyl ether; cyclohexane pH=7; aq. phosphate buffer;
96%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

benzaldehyde p-toluenesulfonylhydrazone
1666-17-7

benzaldehyde p-toluenesulfonylhydrazone

3-(trifluoromethyl)-5-phenylpyrazole
4027-54-7, 948293-66-1

3-(trifluoromethyl)-5-phenylpyrazole

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In toluene at 60℃; for 6h;96%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

4-Ethynylaniline
14235-81-5

4-Ethynylaniline

4-(3-(trifluoromethyl)but-3-en-1-yn-1-yl)aniline

4-(3-(trifluoromethyl)but-3-en-1-yn-1-yl)aniline

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 50℃; Inert atmosphere; Schlenk technique;96%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 50℃; Inert atmosphere; Schlenk technique;
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

benzaldehyde
100-52-7

benzaldehyde

1-phenyl-2-(trifluoromethyl)-2-propen-1-ol
14633-65-9

1-phenyl-2-(trifluoromethyl)-2-propen-1-ol

Conditions
ConditionsYield
With copper(l) chloride; zinc In N,N-dimethyl-formamide 1.) 20 deg C, 4 h, 2.) 50 deg C, 8h;95%
Stage #1: 2-bromo-3,3,3-trifluoropropene With sec.-butyllithium In diethyl ether; cyclohexane at -105℃; for 0.166667h;
Stage #2: benzaldehyde In diethyl ether; cyclohexane at -105 - -50℃; for 2h;
73%
Stage #1: 2-bromo-3,3,3-trifluoropropene With sec.-butyllithium In diethyl ether; cyclohexane at -105℃; for 0.166667h; Inert atmosphere;
Stage #2: benzaldehyde In diethyl ether; cyclohexane at -105 - -50℃; for 2h; Inert atmosphere;
Stage #3: With water In diethyl ether; cyclohexane pH=7; aq. phosphate buffer;
73%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

1-(4-Chloro-phenyl)-2-trifluoromethyl-prop-2-en-1-ol
155014-61-2

1-(4-Chloro-phenyl)-2-trifluoromethyl-prop-2-en-1-ol

Conditions
ConditionsYield
With copper(l) chloride; zinc In N,N-dimethyl-formamide 1.) 20 deg C, 4 h, 2.) 50 deg C, 5h;95%
With zinc In tetrahydrofuran; pyridine at 50℃; Schlenk technique; Inert atmosphere;
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

(3-trifluoromethyl-but-3-en-1-ynyl)trimethylsilane
152327-70-3

(3-trifluoromethyl-but-3-en-1-ynyl)trimethylsilane

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tributyl-amine at 60℃; for 4h;95%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

1-((3S,10R,13S,17S)-10,13-dimethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone
35961-41-2

1-((3S,10R,13S,17S)-10,13-dimethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone

2-[(3S,8S,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-5,5,5-trifluoro-pent-3-yn-2-ol

2-[(3S,8S,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-5,5,5-trifluoro-pent-3-yn-2-ol

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran; cyclohexane 1.) -78 deg C, 10 min, 2.) -78 deg C, 1 h;95%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

3-methoxy-1-iodobenzene
766-85-8

3-methoxy-1-iodobenzene

1-methoxy-3-(3,3,3-trifluoroprop-1-yn-1-yl)benzene
111727-07-2

1-methoxy-3-(3,3,3-trifluoroprop-1-yn-1-yl)benzene

Conditions
ConditionsYield
Stage #1: 2-bromo-3,3,3-trifluoropropene With dichloro(N,N,N’,N‘-tetramethylethylenediamine)zinc; lithium diisopropyl amide In tetrahydrofuran; hexane at -78 - 20℃; for 1h;
Stage #2: 3-methoxy-1-iodobenzene With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; hexane for 6h; Heating;
95%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

N-cyclohexylidenebenzylamine N-oxide
22687-06-5

N-cyclohexylidenebenzylamine N-oxide

N-benzyl-N-(1-cyclohexyl-4,4,4-trifluorobut-2-ynyl)hydroxylamine
1170994-16-7

N-benzyl-N-(1-cyclohexyl-4,4,4-trifluorobut-2-ynyl)hydroxylamine

Conditions
ConditionsYield
Stage #1: 2-bromo-3,3,3-trifluoropropene With lithium diisopropyl amide In tetrahydrofuran at -78℃;
Stage #2: N-cyclohexylidenebenzylamine N-oxide In tetrahydrofuran at -20℃; for 2h;
95%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

3-phenylsydnone
508191-77-3

3-phenylsydnone

1-phenyl-4-(trifluoromethyl)-1H-pyrazole

1-phenyl-4-(trifluoromethyl)-1H-pyrazole

Conditions
ConditionsYield
With 1,10-Phenanthroline; copper(II) bis(trifluoromethanesulfonate); 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 35℃; for 4h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; regioselective reaction;95%
2-bromo-3,3,3-trifluoropropene
1514-82-5

2-bromo-3,3,3-trifluoropropene

tert-butyl (2R)-2-[chloro(hydroxyimino)methyl]pyrrolidine-1-carboxylate
1148049-26-6

tert-butyl (2R)-2-[chloro(hydroxyimino)methyl]pyrrolidine-1-carboxylate

(R)-tert-butyl 2-(5-(trifluoromethyl)isoxazol-3-yl)-pyrrolidine-1-carboxylate

(R)-tert-butyl 2-(5-(trifluoromethyl)isoxazol-3-yl)-pyrrolidine-1-carboxylate

Conditions
ConditionsYield
With sodium hydrogencarbonate In ethyl acetate at 20℃; regioselective reaction;95%

2-Bromo-3,3,3-trifluoropropene Chemical Properties

Molecular Structure of 1-Propene,2-bromo-3,3,3-trifluoro- (CAS NO.10152-76-8):

IUPAC Name: 2-Bromo-3,3,3-trifluoroprop-1-ene
Molecular Formula: C3H2BrF3
Molecular Weight: 174.9472
H bond acceptors: 0
H bond donors: 0
Freely Rotating Bonds: 0
Polar Surface Area: 0 Å2
Index of Refraction: 1.379
Molar Refractivity: 23.7 cm3
Molar Volume: 102.5 cm3
Surface Tension: 18.4 dyne/cm
Density: 1.706 g/cm3
Enthalpy of Vaporization: 30.56 kJ/mol
Boiling Point: 77.9 °C at 760 mmHg
Vapour Pressure: 105 mmHg at 25°C
SMILES: Br/C(=C)C(F)(F)F
InChI: InChI=1/C3H2BrF3/c1-2(4)3(5,6)7/h1H2
Product Categories: Fluorinated Building Blocks; Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds; Synthetic Organic Chemistry; Alkenyl; Halogenated Hydrocarbons; Organic Building Blocks

2-Bromo-3,3,3-trifluoropropene Safety Profile

Hazard Codes: HighlyF+,FlammableF,IrritantXi
Risk Statements: 12-66
R12: Extremely flammable. 
R66: Repeated exposure may cause skin dryness or cracking.
Safety Statements: 24-36 
S24: Avoid contact with skin. 
S36: Wear suitable protective clothing.
RIDADR: UN 1993 3/PG 1
WGK Germany: 3
Hazard Note: Extremely Flammable
HazardClass: Irritant
PackingGroup: I

2-Bromo-3,3,3-trifluoropropene Specification

  1-Propene,2-bromo-3,3,3-trifluoro- , with CAS number of 75-61-6, can be called Carbon 1-propene, 2-bromo-3,3,3-trifluoro- ; 2-Bromo-3,3,3-trifluoro-1-propene ; 2-Bromo-3,3,3-trifluoroprop-1-ene . It is a kind of liquid.

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