2-Butyloxirane supplier | CasNO.1436-34-6

Name
1,2-EPOXYHEXANE
EINECS
CAS No. 1436-34-6
Article Data138
CAS DataBase
Density 0.871g/cm³
Solubility
Melting Point 94°C
Formula C6H12 O
Boiling Point 117.1°Cat760mmHg
Molecular Weight 100.161
Flash Point 21.8°C
Transport Information
Appearance clear colorless liquid
Safety Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.
Risk Codes 11-22-36/37/38
Molecular Structure
Hazard Symbols
Synonyms Hexane,1,2-epoxy- (7CI,8CI); Oxirane, butyl- (9CI); (?à)-1,2-Epoxyhexane; (?à)-Butyloxirane; 1,2-Epoxyhexane; 1,2-Hexene oxide;1-Hexene epoxide; 1-Hexene oxide; 2-Butyloxirane; Butyloxirane; NSC 24268
PSA 12.53000
LogP 1.57540

Synthetic route

: 592-41-6
1-hexene

: 1436-34-6
1,2-Epoxyhexane

Conditions

Conditions	Yield
With C20H24CoN2O6(1+)NO3(1-)H2O; oxygen; isobutyraldehyde In acetonitrile at 60℃; under 760.051 Torr; for 8h; Time; chemoselective reaction;	100%
With dihydrogen peroxide; (Bu4N)3K[γ-SiW10O36(PhPO)2] In water at 65℃; for 2h; microwave irradiation;	99%
With tert.-butylhydroperoxide In acetonitrile at 65 - 68℃; for 24h;	99%

: 1-iodo-2-hexanol

: 1436-34-6
1,2-Epoxyhexane

Conditions

Conditions	Yield
With Al2O3-Na2CO3 catalyst at 40 - 45℃; for 0.00833333h; Microwave irradiation;	98%

: 10353-53-4
1,2-epoxy-5-hexene

: 1436-34-6
1,2-Epoxyhexane

Conditions

Conditions	Yield
With [Fe(nacnac)dippCH2SiMe3]; N-butylamine; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In benzene-d6 at 20℃; for 1h; Sealed tube; Schlenk technique; Glovebox; Inert atmosphere;	91%

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 111-27-3
hexan-1-ol

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; Y2(N3)(nic)2(OH)3(Hnic)(H2O) In acetonitrile at 68 - 70℃; for 24h;	A 85% B 10%

: 4050-45-7
trans-2-hexene

A: 1436-34-6
1,2-Epoxyhexane

: 6124-91-0
trans-2,3-epoxyhexane

: 6124-90-9
cis-2,3-epoxyhexane

D: 123-72-8
butyraldehyde

Conditions

Conditions	Yield
With oxygen; titanium(IV) oxide for 19h; Irradiation;	A n/a B 66% C n/a D n/a

...Expand

: 119101-55-2
1,2-epoxy-2-hexyl(triphenyl)silane

: 1436-34-6
1,2-Epoxyhexane

Conditions

Conditions	Yield
With potassium fluoride; N-benzyl-N,N,N-triethylammonium chloride In dimethyl sulfoxide for 2h; Ambient temperature;	65%

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 6920-22-5
Hexane-1,2-diol

Conditions

Conditions	Yield
With poly{[CuMg(pyridine-2,5-dicarboxylate)2(H2O)4]*2H2O}; dihydrogen peroxide In acetonitrile at 60℃; for 24h; Catalytic behavior;	A 22% B 61%
With dihydrogen peroxide; large pore titanium silicate (MCM-41) In methanol at 55.9℃; for 5h; Product distribution; other hydrocarbon; var. oxidation compounds; var. time;
With urea-hydrogen peroxide; tegafur In methanol at 39.85℃; for 12h; Product distribution; Further Variations:; Reagents;

: 7688-21-3
cis-2-hexene

A: 1436-34-6
1,2-Epoxyhexane

: 6124-91-0
trans-2,3-epoxyhexane

: 6124-90-9
cis-2,3-epoxyhexane

D: 123-72-8
butyraldehyde

Conditions

Conditions	Yield
With oxygen; titanium(IV) oxide for 19h; Irradiation;	A n/a B n/a C 61% D n/a

...Expand

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 626-93-7
n-hexan-2-ol

C: 591-78-6
n-hexan-2-one

Conditions

Conditions	Yield
With iodosylbenzene; (n-Bu4N)4H(Mn)PW11O39 In acetonitrile at 24℃; for 2h; Product distribution; other reagent, other catalysts, other time;	A 58% B n/a C 3.5%
With sodium tetrahydroborate; 5,10,15,20-tetra(4-methoxyphenyl) porphyrinato manganese chloride; oxygen In ethanol; benzene for 24h; Product distribution;

...Expand

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 591-78-6
n-hexan-2-one

Conditions

Conditions	Yield
With iodosylbenzene; (n-Bu4N)4H(Mn)PW11O39 In acetonitrile at 24℃; for 2h;	A 58% B 3.5%
With tert.-butylhydroperoxide; 2C21H13N3O6(2-)4Co(2+)HO(1-)*17H2O In neat (no solvent) at 50℃; for 4h; Green chemistry;	A 80 %Chromat. B 20 %Chromat.
With C60H62Fe2Li2N10O7(2+)*2ClO4(1-); dihydrogen peroxide; acetic acid In water; acetonitrile at 30℃; for 3h;	A 15 %Chromat. B n/a

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 636-36-2, 6064-63-7
rac-2-hydroxyhexanoic acid

C: 109-52-4
valeric acid

Conditions

Conditions	Yield
With [γ-W10SiO36(PhPO)2][TBA]4; dihydrogen peroxide In acetonitrile at 90 - 120℃; for 0.833333h; microwave irradiation;	A 50% B n/a C n/a

...Expand

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 4798-44-1
1-hexene-3-ol

Conditions

Conditions	Yield
With iodosylbenzene; meso-tetrakis(tetraphenyl)porphyrin iron(III) chloride In benzene at 20℃; for 1h;	A 40% B 3%
With 1H-imidazole; C44H28MnN4O12S4(1+)*C2H3O2(1-); tetrabutylammonium periodite In dichloromethane at 20℃; for 4h; Reagent/catalyst;	A 14% B 7%
With P450 In phosphate buffer at 37℃; pH=7.4; Enzyme kinetics;

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 66-25-1
hexanal

Conditions

Conditions	Yield
With dihydrogen peroxide In acetonitrile at 65 - 68℃; for 24h;	A 35% B 13%

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 4798-44-1
1-hexene-3-ol

C: 1629-60-3
1-hexene-3-one

D: 66-25-1
hexanal

Conditions

Conditions	Yield
With iodosylbenzene; 5,10,15,20-tetraphenyl-21 H,23-H-porphine manganese(III)chloride In benzene for 2h; Ambient temperature; anaerobic cond.;	A 29% B 4% C 3% D 1%
With iodosylbenzene; 5,10,15,20-tetraphenyl-21 H,23-H-porphine manganese(III)chloride In benzene at 20℃; for 1h; Product distribution; regioselectivity of the oxidation of olefins in presence of various metalloporphyrins;	A 29% B 4% C 3% D 1%
5,10,15,20-tetraphenyl-21 H,23-H-porphine manganese(III)chloride In benzene for 2h; Product distribution; Mechanism; Ambient temperature; variations of pH, reagents, pO2, T;	A 29% B 4% C 3% D 1%

...Expand

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 96128-93-7
1-hexene oxide dimer

Conditions

Conditions	Yield
With dihydrogen peroxide; iron(III) chloride In acetonitrile at -5℃; for 0.166667h; Product distribution; Mechanism; other alkenes, alkanes, alcohols, ethers, aldehydes, thioethers and sulfoxides; other temperature, other time;	A 71 % Chromat. B 10 % Chromat.

: 94444-14-1
6-iodo-1,2-epoxyhexane

: 1436-34-6
1,2-Epoxyhexane

Conditions

Conditions	Yield
With methanol; tert.-butyl lithium 1.) Et2O, pentane, -78 deg C.; Yield given. Multistep reaction;

: 67-56-1
methanol

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 25246-71-3
2-n-hexyl methyl ether

C: 4747-07-3
hexyl methyl ether

Conditions

Conditions	Yield
With dihydrogen peroxide; Ti-β zeolite at 59.9℃; for 5h; Product distribution; var. of catalyst;

...Expand

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 626-93-7
n-hexan-2-ol

C: 6920-22-5
Hexane-1,2-diol

D: 4798-44-1
1-hexene-3-ol

E: 66-25-1
hexanal

F: 111-27-3
hexan-1-ol

Conditions

Conditions	Yield
With europioum(III) chloride; oxygen; propionic acid; zinc In 1,2-dichloro-ethane at 40℃; for 1h; Product distribution; various catalysts, various solvents, other alkenes;

...Expand

: 67-56-1
methanol

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 80717-22-2
1-hydroxy-2-methoxyhexane

C: 80717-20-0
1-methoxy-2-hexanol

Conditions

Conditions	Yield
With Ti-Beta catalyst; dihydrogen peroxide at 50℃; for 2h; Product distribution; selectivity to epoxide; var. olefins; other catalyst and oxidating agent; var. reaction time;

...Expand

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 591-78-6
n-hexan-2-one

C: 66-25-1
hexanal

D: 142-62-1
hexanoic acid

E: 109-52-4
valeric acid

Conditions

Conditions	Yield
Product distribution; Ambient temperature; electrochemical oxidation, var. voltage, var. anodes;

...Expand

(+-)-1-chloro-hexan-2-ol: (+-)-1-chloro-hexan-2-ol

: 1436-34-6
1,2-Epoxyhexane

Conditions

Conditions	Yield
With sodium hydroxide; diethyl ether
With sodium hydroxide; water

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 110-62-3
pentanal

C: 6920-22-5
Hexane-1,2-diol

Conditions

Conditions	Yield
With dihydrogen peroxide; peroxy-niobic acid In water at 34.85℃; for 24h;	A 27 % Chromat. B 20 % Chromat. C 15 % Chromat.

...Expand

: 26818-04-2
1-bromohexan-2-ol

: 1436-34-6
1,2-Epoxyhexane

Conditions

Conditions	Yield
With ammonia

: 592-41-6
1-hexene

A: 1436-34-6
1,2-Epoxyhexane

B: 6920-22-5
Hexane-1,2-diol

C: 4798-44-1
1-hexene-3-ol

D: 1629-60-3
1-hexene-3-one

Conditions

Conditions	Yield
With dihydrogen peroxide; [Ti,Al]-Beta In methanol at -240.15℃; for 3h; Product distribution; Further Variations:; Catalysts;

...Expand

: β-hydroxy-n-hexyl(tetraphenylporphyrinato)rhodium(III)

: 1436-34-6
1,2-Epoxyhexane

Conditions

Conditions	Yield
With 18-crown-6 ether; potassium tert-butylate In benzene-d6 at 25℃; for 0.0833333h;

: 592-41-6
1-hexene

[[2,6-iPr2C6H3-N=C(Me)-C(Me)=N-C6H3(2,6-iPr2)]Pd-(CH2)3C(O)OMe](1+): [[2,6-iPr2C6H3-N=C(Me)-C(Me)=N-C6H3(2,6-iPr2)]Pd-(CH2)3C(O)OMe](1+)

: 1436-34-6
1,2-Epoxyhexane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 82 percent / NBS / H2O 2: NH3*H2O View Scheme

: 75-21-8
oxirane

: 592-41-6
1-hexene

aqueous HOCl: aqueous HOCl

nonylphenol ethoxylate: nonylphenol ethoxylate

: 1436-34-6
1,2-Epoxyhexane

Conditions

Conditions	Yield
With sodium hydroxide; sodium chloride In water

...Expand

: 142-28-9
1,3-Dichloropropane

: 627-30-5
1-chloro-3-hydroxypropane

A: 930-37-0
glycidyl methyl ether

B: 1436-34-6
1,2-Epoxyhexane

C: 78-88-6
2,3-Dichloroprop-1-ene

D: 5976-47-6
2-chloroallyl alcohol

E: 3175-23-3
1,2,2-trichloropropane

F: 26198-63-0, 78-87-5
1,2-Dichloropropane

G: 10061-01-5
(Z)-1,3-dichloropropene

H: 13116-58-0
1,2,3-trichloro-1-propene

I: 96-19-5, 13116-58-0, 13116-57-9
(1Z)-1,2,3-trichloroprop-1-ene

J: 2953-50-6
1,3,3-trichloro-propene

K: 2598-01-8
1t,3,3-trichloro-propene

L: 124-48-1
chlorodibromomethane

M: 598-77-6
1,1,2-trichloropropane

N: 616-23-9
2,3-Dichloro-1-propanol

O: 96-23-1
1,3-Dichloro-2-propanol

P: 96-18-4
1,2,3-trichloropropane

Q: 563-57-5
3,3-dichloropropene

R: 2567-14-8
3,3-dichloroallyl chloride

S: 75-07-0
acetaldehyde

T: 107-18-6
allyl alcohol

U: 116-09-6
hydroxy-2-propanone

V: 78-95-5
chloroacetone

W: 120-92-3
cyclopentanone

X: 108-90-7
chlorobenzene

Y: 67-63-0
isopropyl alcohol

Z: 96-24-2
3-monochloro-1,2-propanediol

[: 107-02-8
acrolein

\: 106-89-8
epichlorohydrin

]: 10061-02-6
(E)-1,3-dichloro-prop-1-ene

Conditions

Conditions	Yield
With sodium hydroxide; water at 45 - 62.4℃; under 112.511 - 750.075 Torr; Product distribution / selectivity;

...Expand

: 1167549-15-6
Rh(III)(tetra(p-sulfonatophenyl)porphyrinato)(CH2CH(OD)CH2CH2CH2CH3)(OD2)(4-)

A: 1436-34-6
1,2-Epoxyhexane

B: [(TSPP)Rh(D)(D2O)](4-)

Conditions

Conditions	Yield
With potassium hydroxide In dimethyl sulfoxide at 20℃; for 0.0833333h;

: 1436-34-6
1,2-Epoxyhexane

: 6920-22-5
Hexane-1,2-diol

Conditions

Conditions	Yield
With water; erbium(III) triflate In acetonitrile at 25℃; for 1h;	100%
With poly{[CuBa(pyridine-2,5-dicarboxylate)2(H2O)5]*H2O}; dihydrogen peroxide In water; acetonitrile at 40℃; for 2h; Catalytic behavior; Reagent/catalyst;	100%
With water at 40℃; for 8h; Autoclave;	99%

: 1436-34-6
1,2-Epoxyhexane

: 592-41-6
1-hexene

Conditions

Conditions	Yield
With triphenylphosphine at 200℃; for 6h;	100%
With carbon monoxide; C29H32IrN5O; bis(trifluoromethane)sulfonimide lithium In benzene-d6 at 80℃; under 7500.75 Torr; for 24h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Time; Schlenk technique; chemoselective reaction;	98%
With zirconium(IV) chloride; sodium iodide In acetonitrile for 0.0166667h; Heating;	88%

: 1436-34-6
1,2-Epoxyhexane

: 124-38-9
carbon dioxide

: 66675-43-2
4-butyl-1,3-dioxolan-2-one

Conditions

Conditions	Yield
With tetra-(n-butyl)ammonium iodide; 1,3,5-trimethyl-benzene; 2-hydroxyresorcinol In butanone at 45℃; under 3750.38 - 7500.75 Torr; for 18h; Autoclave;	100%
With C26H42N5(3+)*3Br(1-); 1,1'-hexane-1,6-diylbis(1-methylpyrrolidinium) bis(trifluromethane)sulfonamide at 80℃; under 30003 Torr; for 3h; Autoclave; Green chemistry;	100%
With potassium iodide In neat (no solvent) at 80℃; under 5250.53 Torr; Catalytic behavior; Autoclave;	100%

: 1436-34-6
1,2-Epoxyhexane

: 18982-54-2
o-bromobenzyl alcohol

: (R)-1-(2-bromobenzyloxy)-2-hexanol

Conditions

Conditions	Yield
With chiral oligo-(salen)Co(OTs) complexes; lutidinium p-toluene sulfonate In acetonitrile at 4℃; for 24h;	100%
With Co(salen) macrocycles 1(OTs) In acetonitrile at 4℃; for 24h; optical yield given as %ee; enantioselective reaction;	97%

: 123-75-1
pyrrolidine

: 1436-34-6
1,2-Epoxyhexane

: 225117-10-2
1-n-butyl-2-pyrrolidinyl ethanol

Conditions

Conditions	Yield
With calcium bistrifluoroacetate In neat (no solvent) at 40℃; for 31h; regioselective reaction;	100%
With zinc(II) chloride In acetonitrile for 12h; Heating;	66%
With C8H18N2(2+)*2C2F6NO4S2(1-) In dichloromethane at 20℃; for 24h; Reagent/catalyst; Molecular sieve; Schlenk technique; Inert atmosphere; regioselective reaction;

: 1436-34-6
1,2-Epoxyhexane

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 878-15-9, 5532-44-5, 5595-61-9
trans-2-butylcyclopropanecarboxylic acid ethyl ester

Conditions

Conditions	Yield
With n-butyllithium In 1,2-dimethoxyethane; hexane at 130℃; for 16h; Sealed tube;	100%
With n-butyllithium In 1,2-dimethoxyethane at 130℃; for 18h; Sealed tube; Inert atmosphere;	68%

: 1436-34-6
1,2-Epoxyhexane

: 74-89-5
methylamine

: 1343267-21-9
1-(methylamino)hexan-2-ol

Conditions

Conditions	Yield
With calcium bistrifluoroacetate In neat (no solvent) at 40℃; for 31h; regioselective reaction;	100%
In methanol; water at 140℃; under 15514.9 Torr; for 0.166667h; Flow reactor;	75%

: 1436-34-6
1,2-Epoxyhexane

: 4468-63-7, 59854-39-6
2-butyl thiirane

Conditions

Conditions	Yield
With ruthenium trichloride; ammonium thiocyanate In acetonitrile at 25℃; for 0.25h;	99%
With ammonium thiocyanate at 60℃; for 0.366667h; Neat (no solvent);	97%
With cross-linked polystyrene supported aluminium chloride; thiourea In acetonitrile for 2h; Heating;	95%

: 1436-34-6
1,2-Epoxyhexane

: 67-64-1
acetone

: 93339-59-4
4-butyl-2,2-dimethyl-[1,3]dioxolane

Conditions

Conditions	Yield
erbium(III) triflate at 20℃; for 1h;	99%
With trichloro(trifluoromethanesulfonato)titanium(IV); n-tetrabutylammonium hydroxide In water for 0.166667h; Ambient temperature;	93%
With 12-molybdo phosphoric acid n-hydrate at 20℃; for 0.0166667h; neat (no solvent);	93%

: 1436-34-6
1,2-Epoxyhexane

: 108-39-4
3-methyl-phenol

: (S)-1-(3-methylphenoxy)hexan-2-ol

Conditions

Conditions	Yield
With (R,R)-(salen)Co(H2O); 3 A molecular sieve In various solvent(s) at 25℃; for 16h;	99%
With 1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-ol; polysytrene-immobilized chiral Co-salen complex In tetrahydrofuran at 20℃; for 24h;	96%
In acetonitrile at 23℃; for 14h; enantioselective reaction;	95%
With Co(salen) macrocycles 1(OTs) In tert-butyl methyl ether at 20℃; for 19h; optical yield given as %ee; enantioselective reaction;	91%

: 1436-34-6
1,2-Epoxyhexane

: 108-95-2
phenol

: (2S)-1-phenoxyhexan-2-ol

Conditions

Conditions	Yield
With 1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-ol; polystyrene-immobilized chiral Co-salen complex In tetrahydrofuran at 20℃; for 17h;	99%
With (R,R)-(salen)Co(H2O); 3 A molecular sieve In various solvent(s) at 25℃; for 12h;	97%
With Co(salen) macrocycles 1(OTs) In tert-butyl methyl ether at 4℃; for 24h; optical yield given as %ee; enantioselective reaction;	97%
In acetonitrile at 23℃; for 16h; enantioselective reaction;	92%
Stage #1: 1,2-Epoxyhexane With 3 A molecular sieve; fluorous (R,R)-(salen)cobalt(III) In various solvent(s) for 0.0833333h; Stage #2: phenol In various solvent(s) for 18h;	53%

: 1436-34-6
1,2-Epoxyhexane

: 4248-19-5
tert-butyl carbamate

A: 1436-34-6, 122922-40-1, 130404-08-9, 104898-06-8
(R)-1,2-epoxyhexane

B: ((S)-2-hydroxyhexyl)carbamic acid tert-butyl ester

Conditions

Conditions	Yield
With air; 4-nitro-benzoic acid; (R,R)-((t-Bu)4-salen)Co(II) In various solvent(s) at 20℃; for 24h;	A n/a B 99%
With (1R,2R)-(-)-N,N'-bis(3,5-di-tert-butylsalicydene)-1,2-cyclohexanediaminocobalt(II); 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; 4-nitro-benzoic acid at 20℃; for 10h; optical yield given as %ee; enantioselective reaction;

...Expand

: 1436-34-6
1,2-Epoxyhexane

poly(hexene oxide): poly(hexene oxide)

Conditions

Conditions	Yield
C64H74Cl2Co2N4O4; bis(triphenylphosphoranylidene)-ammonium acetate In toluene at 0℃; for 15h;	99%

: 1436-34-6
1,2-Epoxyhexane

: 111-27-3
hexan-1-ol

: 1247064-78-3
C12H26O2

Conditions

Conditions	Yield
With Co(salen) macrocycles 1(OTs) In acetonitrile at 20℃; for 4h; optical yield given as %ee; enantioselective reaction;	99%

: 1436-34-6
1,2-Epoxyhexane

: 52802-07-0
1-chloro-hexan-2-ol

Conditions

Conditions	Yield
With chloro-trimethyl-silane; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate at 20℃; for 1h; ring opening reaction;	98%
With magnesium; tin(ll) chloride In tetrahydrofuran for 0.5h; Ambient temperature;	77%
With water; silica gel; lithium chloride for 17h; Ambient temperature;	76%

: 1436-34-6
1,2-Epoxyhexane

: 95-57-8
2-monochlorophenol

: (2S)-1-(2-chlorophenoxy)hexan-2-ol

Conditions

Conditions	Yield
With chiral oligo-(salen)Co(OTs) complexes; lutidinium p-toluene sulfonate In acetonitrile at 4℃; for 6h;	98%
In acetonitrile at 23℃; for 6h; enantioselective reaction;	97%
With water; macrocyclic salen type Co In acetonitrile at 4℃; for 10h;	95%
With 4 A molecular sieve; lutidinium p-toluene sulfonate; chiral oligo-(salen)Co(OTs) complexes In acetonitrile at 30℃; Kinetics; Further Variations:; concentration of catalyst; concentration of reagent;

: 1436-34-6
1,2-Epoxyhexane

: 612-25-9
2-Nitrobenzyl alcohol

: (S)-1-(2-nitrobenzyloxy)-2-hexanol

Conditions

Conditions	Yield
With chiral oligo-(salen)Co(OTs) complexes; lutidinium p-toluene sulfonate In acetonitrile at 4℃; for 24h;	98%

: 1436-34-6
1,2-Epoxyhexane

: 930-35-8
1,3-dithiol-2-thione

: 138197-10-1
2-Butyl-1-oxa-4,6,9-trithiaspiro<4.4>non-7-en

Conditions

Conditions	Yield
With magnesium(II) perchlorate In acetonitrile for 12h; Heating;	97%

: 1436-34-6
1,2-Epoxyhexane

: 2916-68-9
2-(Trimethylsilyl)ethanol

: (S)-1-(2-trimethylsilyl ethoxy)-2-hexanol

Conditions

Conditions	Yield
With water; macrocyclic salen-type Co-complex In acetonitrile at 4℃; for 2h;	97%
With chiral oligo-(salen)Co(OTs) complexes; lutidinium p-toluene sulfonate In acetonitrile at 4℃; for 3h;	97%

: 1436-34-6
1,2-Epoxyhexane

: 100-46-9
benzylamine

: 1-(benzylamino)hexan-2-ol

Conditions

Conditions	Yield
With calcium bistrifluoroacetate In neat (no solvent) at 40℃; for 31h; regioselective reaction;	97%
With sulfated zirconia at 60℃; for 6h;	82%

: 1436-34-6
1,2-Epoxyhexane

: (2-hydroxy-5-methylphenyl)triphenylphosphonium iodide

: (2-(2-hydroxyhexyloxy)-5-methylphenyl)triphenylphosphonium iodide

Conditions

Conditions	Yield
In chlorobenzene at 100℃; for 2h;	97%

: 1436-34-6
1,2-Epoxyhexane

: 124718-84-9
2-Hydroxyhexylazide

Conditions

Conditions	Yield
With sodium azide; cerium(III) chloride In water; acetonitrile for 6h; Heating;	96%
With PEG-400; sodium azide at 20℃; for 0.75h;	95%
With sodium azide; ammonium chloride In methanol; water at 20℃; for 24h;	94%

: 1436-34-6
1,2-Epoxyhexane

: 108-24-7
acetic anhydride

: 22007-57-4, 140238-23-9, 140238-24-0
pentane-1,2-diyl diacetate

Conditions

Conditions	Yield
With tributylphosphine In toluene Heating;	96%
With zeolite HY at 20℃; for 9.5h;	95%
With sodium phosphate dibasic dodecahydrate for 2h; Catalytic behavior; Reagent/catalyst; Reflux;	90%
With antimony(III) fluoride for 2h; Reflux; regioselective reaction;	80%

: 1436-34-6
1,2-Epoxyhexane

: 67-56-1
methanol

: (R)-1-methoxy-2-hexanol

Conditions

Conditions	Yield
With Co(salen) macrocycles 1(OTs) In acetonitrile at 20℃; for 3h; optical yield given as %ee; enantioselective reaction;	96%

: 1436-34-6
1,2-Epoxyhexane

: 95-56-7
2-hydroxybromobenzene

: 233770-25-7
(2S)-1-(2-bromophenoxy)hexan-2-ol

Conditions

Conditions	Yield
In acetonitrile at 23℃; for 6h; Reagent/catalyst; enantioselective reaction;	96%

: 1436-34-6
1,2-Epoxyhexane

: 75-15-0
carbon disulfide

: 4-n-butyl-1,3-dithiolane-2-thione

Conditions

Conditions	Yield
With 1-n-butyl-3-methylimidazolim bromide; potassium hydroxide; lithium bromide In neat (no solvent) at 70℃; for 24h; chemoselective reaction;	96%

: 1436-34-6
1,2-Epoxyhexane

: 79-41-4
poly(methacrylic acid)

: 48063-75-8
2-hydroxyhexyl methacrylate

Conditions

Conditions	Yield
orthosilicic acid tetrakis-2,2,6,6-tetramethyl-4-hydroxy-1-oxylpiperidyl ester at 120℃; for 6h;	95.2%

: 1436-34-6
1,2-Epoxyhexane

: 106-44-5
p-cresol

: 1-p-tolyloxy-hexan-2-ol

Conditions

Conditions	Yield
With (R,R)-(salen)Co(H2O); 3 A molecular sieve In various solvent(s) at 25℃; for 12h;	95%

2-Butyloxirane Chemical Properties

IUPAC Name: 2-Butyloxirane
The molecular formula of 2-Butyloxirane (CAS NO.1436-34-6) is C₆H₁₂O.

The molecular weight of 2-Butyloxirane (CAS NO.1436-34-6) is 100.16.
Synonyms of 2-Butyloxirane (CAS NO.1436-34-6): 2-Butyloxirane ; Hexene oxide ; 2-Hexene oxide ; 1,2-Hexeneoxide
Product Categories: Oxiranes;Simple 3-Membered Ring Compounds
Apperance: clear colorless liquid
Index of Refraction: 1.425
EINECS: 215-864-6
Density: 0.871 g/ml
Flash Point: 21.8 °C
Boiling Point: 117.1 °C
Storage temp: 2-8 °C
BRN: 102568

2-Butyloxirane Uses

2-Butyloxirane (CAS NO.1436-34-6) is used as chemical reagent, organic intermediates, fine chemicals, pharmaceutical research and development.

2-Butyloxirane Toxicity Data With Reference

1.		mmo-sat 20 µmol/plate		BCPCA6 Biochemical Pharmacology. 29 (1980),1068.
2.		sce-ham:lng 1250 µmol/L		MUREAV Mutation Research. 249 (1991),55.

2-Butyloxirane Safety Profile

Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.Safety information of 2-Butyloxirane (CAS NO.1436-34-6):
Hazard Codes F, Harmful Xn
Risk Statements 11-22-36/37/38
R11:Highly flammable.
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR UN 1993 3/PG 2
WGK Germany 3
RTECS MO3630000
F 10-21
HazardClass 3
PackingGroup III

Product Name

1,2-EPOXYHEXANE

Synthetic route

2-Butyloxirane Chemical Properties

2-Butyloxirane Uses

2-Butyloxirane Toxicity Data With Reference

2-Butyloxirane Safety Profile

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