As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiry1-Boc-hexahydro-1,4-diazepine CAS No.:112275-50-0 Name: 1-Boc-hexahydro-1,4-diazepine Synonyms: 1-Boc-homopiperazine; tert-Butyl 1,4-diazepane-1-carboxylate; tert-Butyl homopiperazine-1-carboxylate
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiryShanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:112275-50-0
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:112275-50-0
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inquiryLIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.
Cas:112275-50-0
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FOB Price: $0.9 / 1.0
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inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryProduct Name: tert-Butyl 1,4-diazepane-1-carboxylate CAS No.: 112275-50-0 Molecular formula: C10H20N2O2 Molecular weight: 200 Appearance: white powder Storage:Store in cool and dry place, away f
Cas:112275-50-0
Min.Order:1 Kilogram
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inquiry1-Boc-hexahydro-1,4-diazepine Basic information Product Name: 1-Boc-hexahydro-1,4-diazepine Synonyms: [1,4]DIAZEPANE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-BOC-HEXAHYDRO-1,4-DIAZEPINE;1-BOC-HOMOPIPERAZINE;1-BOC-1,4-DIAZEPANE;TERT-BUTYL HOMOPIPERA
Cas:112275-50-0
Min.Order:1 Kilogram
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inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:112275-50-0
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FOB Price: $20.0 / 24.0
Type:Trading Company
inquiry1-Boc-hexahydro-1,4-diazepine CAS:112275-50-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality o
Cas:112275-50-0
Min.Order:1 Gram
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:112275-50-0
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Type:Lab/Research institutions
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:112275-50-0
Min.Order:4 Kilogram
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:112275-50-0
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inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:112275-50-0
Min.Order:10 Gram
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Type:Lab/Research institutions
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
Cas:112275-50-0
Min.Order:1 Milligram
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Type:Trading Company
inquiryProduct Name: 1-Boc-hexahydro-1,4-diazepine Synonyms: [1,4]DIAZEPANE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-BOC-HEXAHYDRO-1,4-DIAZEPINE;1-BOC-HOMOPIPERAZINE;1-BOC-1,4-DIAZEPANE;1-(TERT-BUTOXYCARBONYL)HOMOPIPERAZINE;BOC-HOMOPIPERAZINE;BOC-HOPIZ;BOC-
Cas:112275-50-0
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Type:Lab/Research institutions
inquiryWe Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
My Company Changchun Artel Import and Export trade companyImport and Export Trade Co., Ltd.is located in Changchun, a national historical and cultural city, Jilin Province, China. It covers an area of 22,000 square meters, construction area
Cas:112275-50-0
Min.Order:20 Metric Ton
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Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:112275-50-0
Min.Order:1 Gram
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Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:112275-50-0
Min.Order:1 Metric Ton
FOB Price: $7.0 / 8.0
Type:Trading Company
inquiryAppearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea
Product Name: 1-Boc-hexahydro-1,4-diazepine Synonyms: [1,4]DIAZEPANE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-BOC-HEXAHYDRO-1,4-DIAZEPINE;1-BOC-HOMOPIPER…Appearance:Solid powder Storage:Sealed,light and oxygen resistant Package:aluminum foil bag,carton
Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
Cas:112275-50-0
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Type:Lab/Research institutions
inquiryhigh quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
Cas:112275-50-0
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inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou
Cas:112275-50-0
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Type:Lab/Research institutions
inquiry1,4-Diazacycloheptane
di-tert-butyl dicarbonate
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
In dichloromethane at 0℃; for 2h; | 98% |
In acetic acid at 20℃; for 24h; | 90% |
In dichloromethane at 0℃; | 88% |
1,4-Diazacycloheptane
N-(tert-butyloxycarbonyl) azide
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
In ethanol; di-isopropyl ether; water at 15℃; for 4h; | 68.9% |
1-(4'-Cyanomethylphenoxy)-2,3-epoxypropane
1-t-Butoxycarbonylpiperazine
B
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
In methanol; ethyl acetate | A n/a B 38.8% |
2-bromo-pyridine
1-(2-pyridinyl)-1,4-diazepane
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
at 150℃; for 12h; |
1,4-Diazacycloheptane
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
With di-tert-butyl dicarbonate at 50℃; |
1-(4'-Cyanomethylphenoxy)-2,3-epoxypropane
1-t-Butoxycarbonylpiperazine
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
In methanol; ethyl acetate |
1,4-Diazacycloheptane
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
With triethylamine In dichloromethane |
tert-butyl 1,4-diazepine-1-carboxylate
N-Benzyloxycarbonyl-L-proline
4-(1-benzyloxycarbonyl-pyrrolidine-2-carbonyl)-[1,4]diazepane-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane | 100% |
cyclobutanone
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
Stage #1: cyclobutanone; tert-butyl 1,4-diazepine-1-carboxylate In 2-methyltetrahydrofuran for 1h; Inert atmosphere; Stage #2: With sodium tetrahydroborate In 2-methyltetrahydrofuran for 26h; Inert atmosphere; | 100% |
Stage #1: cyclobutanone; tert-butyl 1,4-diazepine-1-carboxylate In 1,1-dichloroethane at 20℃; for 1h; Stage #2: With sodium tris(acetoxy)borohydride In 1,1-dichloroethane for 49h; Stage #3: With sodium hydroxide; water In 1,1-dichloroethane for 1h; | 98% |
Stage #1: cyclobutanone; tert-butyl 1,4-diazepine-1-carboxylate With acetic acid In 1,2-dichloro-ethane at 20 - 25℃; Stage #2: With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20 - 25℃; Stage #3: With sodium hydrogencarbonate In water; 1,2-dichloro-ethane at 20 - 25℃; | 96% |
acetone
tert-butyl 1,4-diazepine-1-carboxylate
tert-butyl 4-isopropyl-1,4-diazepane-1-carboxylate
Conditions | Yield |
---|---|
With hydrogen; 1% Pd/C In methanol Molecular sieve; | 100% |
Stage #1: acetone; tert-butyl 1,4-diazepine-1-carboxylate In methanol for 0.0833333h; Inert atmosphere; Molecular sieve; Stage #2: With hydrogenchloride; sodium cyanoborohydride In methanol for 20h; Inert atmosphere; | 93% |
Stage #1: acetone; tert-butyl 1,4-diazepine-1-carboxylate In methanol at 0℃; for 0.333333h; Stage #2: With sodium cyanoborohydride In methanol at 0 - 20℃; for 56.3333h; |
bromochlorobenzene
tert-butyl 1,4-diazepine-1-carboxylate
tert-butyl 4-(4-chlorophenyl)-1,4-diazepane-1-carboxylate
Conditions | Yield |
---|---|
With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene for 23h; Heating / reflux; | 100% |
With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene for 23h; Heating / reflux; | 100% |
tert-butyl 1,4-diazepine-1-carboxylate
2-chloro-4,6-dimethoxy-5-nitro-pyrimidine
4-(4,6-dimethoxy-5-nitro-pyrimidin-2-yl)-[1,4]diazepane-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With triethylamine In ethanol at 0 - 20℃; | 100% |
5-chloro-3-methyl-1,2,4-thiazole
tert-butyl 1,4-diazepine-1-carboxylate
tert-butyl 4-(3-methyl-1,2,4-thiadiazol-5-yl)-1,4-diazepane-1-carboxylate
Conditions | Yield |
---|---|
With triethylamine In ethanol for 2h; Heating; | 100% |
3-amino-5-tert-butylisoxazole
bis(trichloromethyl) carbonate
tert-butyl 1,4-diazepine-1-carboxylate
4-(5-tert-butyl-isoxazol-3-ylcarbamoyl)-[1,4]diazepane-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; | 100% |
Stage #1: 3-amino-5-tert-butylisoxazole; bis(trichloromethyl) carbonate With N-ethyl-N,N-diisopropylamine In dichloromethane for 2.5h; Stage #2: tert-butyl 1,4-diazepine-1-carboxylate With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 3h; | 58% |
Stage #1: 3-amino-5-tert-butylisoxazole; bis(trichloromethyl) carbonate With N-ethyl-N,N-diisopropylamine In dichloromethane for 0.0833333 - 2.5h; Stage #2: tert-butyl 1,4-diazepine-1-carboxylate With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 3h; Product distribution / selectivity; |
isoquinoline-5-sulfonyl chloride hydrochloride
tert-butyl 1,4-diazepine-1-carboxylate
4-(isoquinoline-5-sulfonyl)-[1,4]diazepane-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With triethylamine In dichloromethane for 3h; | 100% |
iodobenzene
tert-butyl 1,4-diazepine-1-carboxylate
4-phenyl-1,4-diazepane-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; DavePhos In 1,4-dioxane; tert-butyl alcohol for 2h; Inert atmosphere; Reflux; | 100% |
6-[1-(6-fluoro-2-pyridyl)pyrazolo[4,3-c]pyridin-6-yl]-N-[(4-methoxyphenyl)methyl]pyrazin-2-amine
tert-butyl 1,4-diazepine-1-carboxylate
tert-butyl 4-[6-[6-[6-[(4-methoxyphenyl)methylamino]pyrazin-2-yl]pyrazolo[4,3-c]pyridin-1-yl]-2-pyridyl]-1,4-diazepane-1-carboxylate
Conditions | Yield |
---|---|
With 4-methyl-morpholine In 1-methyl-pyrrolidin-2-one at 110℃; Sealed tube; | 100% |
tert-butyl 1,4-diazepine-1-carboxylate
N,N-Dimethylcarbamoyl chloride
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran at 20℃; for 2h; | 100% |
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
With potassium fluoride In dimethyl sulfoxide at 100℃; for 144h; Sealed tube; | 100% |
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
With potassium phosphate In 1-methyl-pyrrolidin-2-one at 25 - 90℃; for 16h; | 100% |
1-bromo-4-butene
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
With tetra-(n-butyl)ammonium iodide; potassium carbonate In tetrahydrofuran Reflux; | 100% |
2-chloro-4-fluorobenzonitrile
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 16h; | 100% |
2-chloro-1-phenyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde
tert-butyl 1,4-diazepine-1-carboxylate
4-(3-formyl-1-phenyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-[1,4]diazepane-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
In 1,4-dioxane at 110℃; for 19.5h; Heating / reflux; | 99.5% |
bromobenzene
tert-butyl 1,4-diazepine-1-carboxylate
4-phenyl-1,4-diazepane-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With palladium diacetate; sodium t-butanolate; XPhos In toluene; tert-butyl alcohol at 120℃; Buchwald-Hartwig reaction; Inert atmosphere; | 99% |
With palladium diacetate; sodium t-butanolate; XPhos In toluene; tert-butyl alcohol for 24h; Buchwald-Hartwig Coupling; Reflux; |
para-bromotoluene
tert-butyl 1,4-diazepine-1-carboxylate
4-(4-methylphenyl)-1,4-diazepane-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With palladium diacetate; sodium t-butanolate; XPhos In toluene; tert-butyl alcohol at 160℃; for 0.166667h; Buchwald-Hartwig reaction; Inert atmosphere; Microwave irradiation; | 99% |
With tri-tert-butyl phosphine; α,α,α-trifluorotoluene; palladium diacetate; 2,4,6-tri(tert-butyl)phenol sodium salt In toluene at 100℃; for 1h; Buchwald-Hartwig Coupling; Inert atmosphere; Glovebox; Microwave irradiation; | 89% |
3-formylpyrazolo[1,5-a]pyridine-5-carbonitrile
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
Stage #1: 3-formylpyrazolo[1,5-a]pyridine-5-carbonitrile; tert-butyl 1,4-diazepine-1-carboxylate With acetic acid In dichloromethane for 1h; Reflux; Stage #2: With sodium cyanoborohydride In ethanol; dichloromethane at 20℃; for 17h; | 99% |
Ethyl isothiocyanate
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
With triethylamine In diethyl ether at 20℃; | 99% |
(1aS,6aR)-3,5-dichloro-6,6a-di-hydro-1aH-1-oxa-cyclopropa[a]indene
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
In acetonitrile at 80℃; regioselective reaction; | 99% |
2-benzofuroyl chloride
tert-butyl 1,4-diazepine-1-carboxylate
tert-butyl 4-(benzofuran-2-carbonyl)-homopiperazine-1-carboxylate
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0℃; | 99% |
1-bromo-4-methoxy-benzene
tert-butyl 1,4-diazepine-1-carboxylate
4-(4-methoxyphenyl)-1,4-diazepane-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With palladium diacetate; sodium t-butanolate; XPhos In toluene; tert-butyl alcohol at 120℃; for 10h; Buchwald-Hartwig reaction; Inert atmosphere; | 98% |
With tris-(dibenzylideneacetone)dipalladium(0); potassium tert-butylate; tris-(o-tolyl)phosphine In toluene at 100℃; for 18h; |
4-methoxy-phenyl-sulphonyl chloride
tert-butyl 1,4-diazepine-1-carboxylate
C17H26N2O5S
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane | 98% |
1-(2-(5-bromopentyloxy)-3,5-dibromophenoxy)-2,4-dibromobenzene
tert-butyl 1,4-diazepine-1-carboxylate
tert-butyl 4-(5-(2-(2, 4-Dibromophenoxy)-4,6-dibromophenoxy)pentyl)-1,4-diazepane-1-carboxylate
Conditions | Yield |
---|---|
With potassium carbonate In acetonitrile for 6h; Inert atmosphere; Reflux; | 98% |
cyclopropanecarboxylic acid chloride
tert-butyl 1,4-diazepine-1-carboxylate
cyclopropyl(1,4-N-cycloheptyl-1-yl)methanone hydrochloride
Conditions | Yield |
---|---|
Stage #1: cyclopropanecarboxylic acid chloride; tert-butyl 1,4-diazepine-1-carboxylate With triethylamine In dichloromethane for 1.66667h; Inert atmosphere; Stage #2: With hydrogenchloride In diethyl ether; dichloromethane at 20 - 40℃; for 41h; | 98% |
methyl thioisocyanate
tert-butyl 1,4-diazepine-1-carboxylate
Conditions | Yield |
---|---|
With triethylamine In diethyl ether at 20℃; | 98% |
tert-butyl 1,4-diazepine-1-carboxylate
cyclopropanecarboxylic acid
tert-butyl 4-(cyclopropylaminocarbamoyl)-1,4-N-cycloheptane-1-carboxylate
Conditions | Yield |
---|---|
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 10h; Inert atmosphere; | 98% |
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 10h; | 98% |
2-Thiophenecarbonyl chloride
tert-butyl 1,4-diazepine-1-carboxylate
tert-butyl 4-(thiophene-2-carbonyl)-1,4-diazepane-1-carboxylate
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0℃; | 98% |
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