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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

3-Thiopheneacetonitrile Manufacturer/High quality/Best price/In stock

Cas:13781-53-8

Min.Order:1 Kilogram

FOB Price: $3.0

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Thiopheneacetonitrile

Cas:13781-53-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 13781-53-8 with competitive price

Cas:13781-53-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3-Thiopheneacetonitrile

Cas:13781-53-8

Min.Order:0

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Thiopheneacetonitrile

Cas:13781-53-8

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply 3-Thiopheneacetonitrile

Cas:13781-53-8

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Type:Other

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Henan Tianfu Chemical Co., Ltd.

3-Cyanomethylthiophene Basic information Product Name: 3-Cyanomethylthiophene Synonyms: Thiophen-3-yl-acetonitrile;3-thiopheneacetonitrile:3-cyan

13781-53-8 C6H5NS 3-Cyanomethylthiophene

Cas:13781-53-8

Min.Order:1 Metric Ton

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Type:Lab/Research institutions

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

3-Cyanomethylthiophene

Cas:13781-53-8

Min.Order:1 Milligram

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Type:Trading Company

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

3-Cyanomethylthiophene

Cas:13781-53-8

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

3-Thiopheneacetonitrile

Cas:13781-53-8

Min.Order:0

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-Cyanomethylthiophene cas no. 13781-53-8 98%

Cas:13781-53-8

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Thiophene-3-acetonitrile

Cas:13781-53-8

Min.Order:0

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3-Thiopheneacetonitrile

Cas:13781-53-8

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Type:Other

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DB BIOTECH CO., LTD

Q1: Are you a manufacturer Answer: Yes, we are factory founded on 2012.Q2: How to contact with us Click "contact supplier" And then send us message the product you interest in, you will get reply within 12 hours.Q3:Which kind of payment terms do you

3-Cyanomethylthiophene

Cas:13781-53-8

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

3-Cyanomethylthiophene

Cas:13781-53-8

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city?in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api,?intermediat

3-Cyanomethylthiophene 2-(thiophen-3-yl)acetonitrile

Cas:13781-53-8

Min.Order:0

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

3-CyanoMethylthiophene

Cas:13781-53-8

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Hangzhou Fandachem Co.,Ltd

3-Thiopheneacetonitrile cas 13781-53-8Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

3-Thiopheneacetonitrile cas 13781-53-8

Cas:13781-53-8

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Hangzhou Sartort Biopharma Co., Ltd

Best quality with low priceAppearance:clear yellow to brown liquid Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

3-Thiopheneacetonitrile

Cas:13781-53-8

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Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-CyanoMethylthiophene

Cas:13781-53-8

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Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

3-Thiopheneacetonitrile 13781-53-8

Cas:13781-53-8

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Shanghai Scochem Technology Co., Ltd.

High quality suppliers Application:healing drugs

3-Cyanomethylthiophene

Cas:13781-53-8

Min.Order:0

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Shenzhen Foris Technology Co. LTD

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

3-Thiopheneacetonitrile 13781-53-8

Cas:13781-53-8

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3-Cyanomethylthiophene

Cas:13781-53-8

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LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

3-Thiopheneacetonitrile

Cas:13781-53-8

Min.Order:0

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Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Amadis Chemical offer CAS#13781-53-8;CAT#A807307

Cas:13781-53-8

Min.Order:10 Milligram

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HENAN SUNLAKE ENTERPRISE CORPORATION

Henan Sunlake Enterprise Corporation is located in Henan Province, the central plain of China , Which enjoys favorable geogeaphical position and convenient transportion. The comany was established in june 1998 , until now having more than 18 years

3-Cyanomethylthiophene

Cas:13781-53-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

Best price/ 3-CyanoMethylthiophene CAS NO.13781-53-8

Cas:13781-53-8

Min.Order:0

Negotiable

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Watson International Ltd

Watson International Ltd' has a very strong R&D and technical capacity supported by FCAD's platform. The subsidiaries under FCAD Group have accumulated much know-how of different fine chemical branches. For example, Apnoke Scientific L

3-Thiopheneacetonitrile

Cas:13781-53-8

Min.Order:1 Gram

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Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

3-Cyanomethylthiophene

Cas:13781-53-8

Min.Order:0

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Type:Other

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Synthetic route

3-chlorothiophene
17249-80-8

3-chlorothiophene

sodium cyanoacetate
1071-36-9

sodium cyanoacetate

(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; bis(η3-allyl-μ-chloropalladium(II)) In 1,3,5-trimethyl-benzene at 20 - 140℃; for 5.16667h; Inert atmosphere; Sealed tube; chemoselective reaction;78%
Thien-3-ylboronic acid
6165-69-1

Thien-3-ylboronic acid

chloroacetonitrile
107-14-2

chloroacetonitrile

(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; sodium carbonate In 1,4-dioxane; water at 100℃; for 12h; Inert atmosphere; Sealed tube;53%
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; sodium carbonate In 1,4-dioxane; water at 60℃; for 12h; Inert atmosphere; Sealed tube;
3-Bromomethylthiophene
34846-44-1

3-Bromomethylthiophene

sodium cyanide
143-33-9

sodium cyanide

(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

Conditions
ConditionsYield
tetrabutylammomium bromide In dichloromethane; water Heating / reflux;44%
With ethanol
3-Bromomethylthiophene
34846-44-1

3-Bromomethylthiophene

potassium cyanide

potassium cyanide

(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

Conditions
ConditionsYield
With N-benzyl-N,N,N-triethylammonium chloride In water28%
3-Bromomethylthiophene
34846-44-1

3-Bromomethylthiophene

potassium cyanide
151-50-8

potassium cyanide

(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

Conditions
ConditionsYield
With ethanol
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

[(p-methylphenyl)sulfonylmethyl]isonitrile
38622-91-2, 36635-61-7

[(p-methylphenyl)sulfonylmethyl]isonitrile

(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

Conditions
ConditionsYield
With potassium tert-butylate 1.) THF, -20 deg C, 30 min, 2.) THF, -20 deg C, 30 min; Yield given. Multistep reaction;
Methyl 2-cyano-2-(3-thienyl)acetate
81344-59-4

Methyl 2-cyano-2-(3-thienyl)acetate

(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

Conditions
ConditionsYield
With water; triethylamine Product distribution;
3-Methylthiophene
616-44-4

3-Methylthiophene

(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 1 h / Reflux
2: tetrabutyl ammonium fluoride / acetonitrile; tetrahydrofuran / 0 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; dibenzoyl peroxide
2: N-benzyl-N,N,N-triethylammonium chloride / water
View Scheme
3-Bromomethylthiophene
34846-44-1

3-Bromomethylthiophene

trimethylsilyl cyanide
7677-24-9

trimethylsilyl cyanide

(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran; acetonitrile at 0 - 20℃; Inert atmosphere;4.06 g
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

(Z)-3-Dimethylamino-2-thiophen-3-yl-acrylonitrile

(Z)-3-Dimethylamino-2-thiophen-3-yl-acrylonitrile

Conditions
ConditionsYield
With 2,4-dichlorophenoxyacetic acid dimethylamine In toluene Heating;100%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

methanol
67-56-1

methanol

2-Thiophen-3-yl-acetimidic acid methyl ester; hydrochloride

2-Thiophen-3-yl-acetimidic acid methyl ester; hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In diethyl ether at 0 - 5℃;99%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

2-methylphenyl aldehyde
529-20-4

2-methylphenyl aldehyde

3-(3'-Thienyl)-2-(2''-tolyl)propenenitrile

3-(3'-Thienyl)-2-(2''-tolyl)propenenitrile

Conditions
ConditionsYield
With sodium ethanolate In ethanol98%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

2-(3-thienyl)ethylamine
59311-67-0

2-(3-thienyl)ethylamine

Conditions
ConditionsYield
With indium(III) chloride; sodium tetrahydroborate In tetrahydrofuran at 25℃; for 4h; Inert atmosphere;97%
With diisobutylaluminum borohydride In tetrahydrofuran at 25℃; for 1h; Inert atmosphere;71%
With indium(III) chloride; sodium tetrahydroborate In tetrahydrofuran at 25℃; for 16h; Inert atmosphere;67%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2-((thiophen-3-yl)methyl)benzo[d]thiazole
1427180-57-1

2-((thiophen-3-yl)methyl)benzo[d]thiazole

Conditions
ConditionsYield
With copper diacetate; triethylamine In ethanol at 70℃; for 6h;97%
thiophene-2-carbaldehyde
98-03-3

thiophene-2-carbaldehyde

(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

(Z)-3-Thiophen-2-yl-2-thiophen-3-yl-acrylonitrile
13781-61-8

(Z)-3-Thiophen-2-yl-2-thiophen-3-yl-acrylonitrile

Conditions
ConditionsYield
With sodium methylate In methanol at 30℃; Kinetics; Thermodynamic data; ΔE*, Σ*, A;95%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

benzaldehyde
100-52-7

benzaldehyde

(E)-3-phenyl-2-(3-thienyl)acrylonitrile
13781-54-9

(E)-3-phenyl-2-(3-thienyl)acrylonitrile

Conditions
ConditionsYield
With sodium methylate In methanol at 30℃; Kinetics; Thermodynamic data; ΔE*, Σ*, A;95%
With sodium ethanolate In ethanol94%
With potassium tert-butylate In ethanol Heating;60%
With potassium tert-butylate In ethanol at 20℃; Knoevenagel condensation;60%
With sodium ethanolate In ethanol at 4℃; for 8h;51%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

4-Octyne
1942-45-6

4-Octyne

(Z)-2-propyl-3-(3-thienylmethyl)-2-hexenenitrile
1180490-30-5

(Z)-2-propyl-3-(3-thienylmethyl)-2-hexenenitrile

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)nickel(0); dimethylaluminum chloride; 2-dicyclohexylphosphino-2',4',6'-trimethylbiphenyl In hexane; toluene at 80℃; for 2h; Inert atmosphere; stereoselective reaction;95%
With bis(1,5-cyclooctadiene)nickel (0); dimethylaluminum chloride; 2-dicyclohexylphosphino-2',4',6'-trimethylbiphenyl In hexane; tetradecane; toluene at 80℃; for 2h; Inert atmosphere; regioselective reaction;95%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

2-(thiophen-3-yl) ethanamine hydrochloride
34843-84-0

2-(thiophen-3-yl) ethanamine hydrochloride

Conditions
ConditionsYield
Stage #1: (thiophen-3-yl)acetonitrile With borane-dimethyl sulfide complex In tetrahydrofuran for 16h; Reflux;
Stage #2: With hydrogenchloride In tetrahydrofuran; water at 20℃; for 0.333333h;
94%
Stage #1: (thiophen-3-yl)acetonitrile With dimethylsulfide borane complex In tetrahydrofuran for 16h; Heating / reflux;
Stage #2: With methanol In tetrahydrofuran
94%
Stage #1: (thiophen-3-yl)acetonitrile With dimethylsulfide borane complex In tetrahydrofuran for 16h; Heating / reflux;
Stage #2: With hydrogenchloride; methanol at 20℃; for 0.333333h;
94%
Stage #1: (thiophen-3-yl)acetonitrile With dimethylsulfide borane complex In tetrahydrofuran for 12h; Reflux;
Stage #2: With hydrogenchloride In tetrahydrofuran for 0.5h;
78.5%
Stage #1: (thiophen-3-yl)acetonitrile With borane-THF In tetrahydrofuran at 20℃; Inert atmosphere; Reflux;
Stage #2: With methanol In tetrahydrofuran
Stage #3: With hydrogenchloride In 1,4-dioxane; methanol
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

5-(thiophen-3-ylmethyl)-1H-1,2,3,4-tetrazole

5-(thiophen-3-ylmethyl)-1H-1,2,3,4-tetrazole

Conditions
ConditionsYield
With sodium azide; triethylamine hydrochloride In toluene at 110℃; for 16h; Inert atmosphere;93%
With aluminium trichloride; sodium azide In tetrahydrofuran for 48h; Heating;61%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

4,4-bis(methylthio)but-3-en-2-one
17649-86-4

4,4-bis(methylthio)but-3-en-2-one

(E)-3-Methylsulfanyl-5-oxo-2-thiophen-3-yl-hex-3-enenitrile

(E)-3-Methylsulfanyl-5-oxo-2-thiophen-3-yl-hex-3-enenitrile

Conditions
ConditionsYield
Stage #1: (thiophen-3-yl)acetonitrile With sodium hydride In N,N-dimethyl-formamide; benzene for 0.25h; Metallation;
Stage #2: 4,4-bis(methylthio)but-3-en-2-one In N,N-dimethyl-formamide at 20℃; Substitution;
93%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

ethanol
64-17-5

ethanol

ethyl 2-(thiophen-3-yl)acetimidate hydrochloride

ethyl 2-(thiophen-3-yl)acetimidate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride at 0℃; Pinner reaction;93%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

bis(acetonitrile)diiodotricarbonyltungsten(II)
113350-36-0, 102382-37-6

bis(acetonitrile)diiodotricarbonyltungsten(II)

triphenylphosphine
603-35-0

triphenylphosphine

WI2(CO)3(thiophene-3-acetonitrile)(PPh3)
211744-19-3

WI2(CO)3(thiophene-3-acetonitrile)(PPh3)

Conditions
ConditionsYield
In dichloromethane N2-atmosphere; stirring W-complex with equimolar amt. of PPh3 for 3 min,filtration into equimolar amt. of ligand soln., stirring for 30 min; solvent removal (vac.); elem. anal.;93%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

2-(2,5-diiodothiophen-3-yl)acetonitrile

2-(2,5-diiodothiophen-3-yl)acetonitrile

Conditions
ConditionsYield
With N-iodo-succinimide; toluene-4-sulfonic acid In ethanol at 50℃; for 0.166667h; Green chemistry; regioselective reaction;93%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

Glyoxilic acid
298-12-4

Glyoxilic acid

(2Z)-3-cyano-3-(3-thienyl)acrylic acid
1076169-87-3

(2Z)-3-cyano-3-(3-thienyl)acrylic acid

Conditions
ConditionsYield
With potassium carbonate In methanol for 3h; Knoevenagel Condensation; Reflux;90%
With potassium carbonate In methanol for 3h; Heating / reflux;90%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

methyl iodide
74-88-4

methyl iodide

rac-2-(thiophen-2-yl)propanenitrile
88701-59-1

rac-2-(thiophen-2-yl)propanenitrile

Conditions
ConditionsYield
Stage #1: (thiophen-3-yl)acetonitrile With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
Stage #2: methyl iodide In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
90%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

cyclopropyl(4-fluorophenyl)methanone
772-31-6

cyclopropyl(4-fluorophenyl)methanone

9a-(4-fluorophenyl)-7,8,9,9a-tetrahydrothieno[3,2-g]indolizin-5(4H)-one
1429308-76-8

9a-(4-fluorophenyl)-7,8,9,9a-tetrahydrothieno[3,2-g]indolizin-5(4H)-one

Conditions
ConditionsYield
With tributylphosphine; boron trifluoride diethyl etherate; copper(I) bromide In nitromethane at 90℃; for 18h; Ritter Amidation;90%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

bis(acetonitrile)diiodotricarbonyltungsten(II)
113350-36-0, 102382-37-6

bis(acetonitrile)diiodotricarbonyltungsten(II)

WI2(CO)3(thiophene-3-acetonitrile)2
211744-17-1

WI2(CO)3(thiophene-3-acetonitrile)2

Conditions
ConditionsYield
In dichloromethane N2-atmosphere; stirring W-complex with 2 equiv. of ligand (warm water bath, 90 min, then room temp., 1 h); filtration, solvent removal (vac.); elem. anal.;89%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

2-(thiophene-3-yl) acetamide
13781-66-3

2-(thiophene-3-yl) acetamide

Conditions
ConditionsYield
With water at 130℃; for 1h; Microwave irradiation;88%
With copper(l) iodide; caesium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene In nitromethane; water at 20 - 100℃; for 3h;75%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

methyl (4-methoxyphenyl)carbodithioate
5874-09-9

methyl (4-methoxyphenyl)carbodithioate

2-(4-methoxyphenyl)thieno[2,3-b]thiophene-3-carbonitrile

2-(4-methoxyphenyl)thieno[2,3-b]thiophene-3-carbonitrile

Conditions
ConditionsYield
Stage #1: (thiophen-3-yl)acetonitrile With potassium tert-butylate In 1,4-dioxane at 0℃; for 0.166667h;
Stage #2: methyl (4-methoxyphenyl)carbodithioate In 1,4-dioxane at 0 - 20℃; for 1h;
Stage #3: With iodine In 1,4-dioxane at 90℃;
87%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

α,α'-dichloroazo compound
57908-42-6

α,α'-dichloroazo compound

6,7,8,9-tetrahydro-2-(thiophene-3-yl)methyl-5H-[1,2,4]triazolo[1,5-a]azepine

6,7,8,9-tetrahydro-2-(thiophene-3-yl)methyl-5H-[1,2,4]triazolo[1,5-a]azepine

Conditions
ConditionsYield
With antimonypentachloride In dichloromethane at -60 - 23℃; for 2.16667h;86%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

formic acid ethyl ester
109-94-4

formic acid ethyl ester

3-hydroxy-2-(thien-3-yl)acrylonitrile sodium salt

3-hydroxy-2-(thien-3-yl)acrylonitrile sodium salt

Conditions
ConditionsYield
With sodium methylate In methanol for 2h; Heating;85%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

allyl bromide
106-95-6

allyl bromide

2-allyl-2-(thiophen-3-yl)pent-4-enenitrile
62716-51-2

2-allyl-2-(thiophen-3-yl)pent-4-enenitrile

Conditions
ConditionsYield
Stage #1: (thiophen-3-yl)acetonitrile With sodium hydride In dimethyl sulfoxide at 20℃; for 0.5h; Inert atmosphere;
Stage #2: allyl bromide In dimethyl sulfoxide at 20℃; for 2h; Inert atmosphere;
85%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

4-chlorophenyl cyclopropyl ketone
6640-25-1

4-chlorophenyl cyclopropyl ketone

9a-(4-chlorophenyl)-7,8,9,9a-tetrahydrothieno[3,2-g]indolizin-5(4H)-one
1429308-77-9

9a-(4-chlorophenyl)-7,8,9,9a-tetrahydrothieno[3,2-g]indolizin-5(4H)-one

Conditions
ConditionsYield
With tributylphosphine; boron trifluoride diethyl etherate; copper(I) bromide In nitromethane at 90℃; for 18h; Ritter Amidation;84%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

cyclopropyl phenyl ketone
3481-02-5

cyclopropyl phenyl ketone

9a-phenyl-7,8,9,9a-tetrahydrothieno[3,2-g]indolizin-5(4H)-one
1429308-75-7

9a-phenyl-7,8,9,9a-tetrahydrothieno[3,2-g]indolizin-5(4H)-one

Conditions
ConditionsYield
With tributylphosphine; boron trifluoride diethyl etherate; copper(I) bromide In nitromethane at 90℃; for 18h; Ritter Amidation;84%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

N-Hydroxy-2-thiophen-3-yl-acetamidine
925252-85-3, 155601-61-9

N-Hydroxy-2-thiophen-3-yl-acetamidine

Conditions
ConditionsYield
With potassium carbonate; ammonium chloride In methanol at 60℃; for 12h;83%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

bis-(1-chloro-1-methyl-ethyl)-diazene
29540-62-3

bis-(1-chloro-1-methyl-ethyl)-diazene

1,5-dimethyl-3-((thiophene-3-yl)methyl)-1H-1,2,4-triazole

1,5-dimethyl-3-((thiophene-3-yl)methyl)-1H-1,2,4-triazole

Conditions
ConditionsYield
With antimonypentachloride In dichloromethane at -60 - 23℃; for 2.16667h;83%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

methyl 4-bromocrotonate
1117-71-1

methyl 4-bromocrotonate

methyl 5-(dimethylamino)thiophene-2-carbodithioate

methyl 5-(dimethylamino)thiophene-2-carbodithioate

2-(5-(dimethylamino)thiophen-2-yl)-3-(thiophen-3-yl)thieno[3,2-b]pyridin-5(4H)-one

2-(5-(dimethylamino)thiophen-2-yl)-3-(thiophen-3-yl)thieno[3,2-b]pyridin-5(4H)-one

Conditions
ConditionsYield
Stage #1: (thiophen-3-yl)acetonitrile With lithium diisopropyl amide In tetrahydrofuran at 0℃; for 0.166667h;
Stage #2: methyl 5-(dimethylamino)thiophene-2-carbodithioate In tetrahydrofuran at 0℃; for 0.5h;
Stage #3: methyl 4-bromocrotonate In tetrahydrofuran at 0 - 20℃; for 8.5h;
82%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

hexachlorobenzene
118-74-1

hexachlorobenzene

α-(3-Thiophene-yl)-α-(2,3,4,5,6-pentachlorophenyl)acetonitrile

α-(3-Thiophene-yl)-α-(2,3,4,5,6-pentachlorophenyl)acetonitrile

Conditions
ConditionsYield
With n-butyllithium In diethyl ether 1.) -70 deg C, 2 h, 2.) -70 deg C to r.t.; r.t., overnight;80%
(thiophen-3-yl)acetonitrile
13781-53-8

(thiophen-3-yl)acetonitrile

methyl fluorobenzenedithiocarboxylate
5969-47-1

methyl fluorobenzenedithiocarboxylate

2-(4-fluorophenyl)thieno[2,3-b]thiophene-3-carbonitrile

2-(4-fluorophenyl)thieno[2,3-b]thiophene-3-carbonitrile

Conditions
ConditionsYield
Stage #1: (thiophen-3-yl)acetonitrile With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.166667h;
Stage #2: methyl fluorobenzenedithiocarboxylate In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 1h;
Stage #3: With tetrabutylammomium bromide; copper diacetate; palladium diacetate In N,N-dimethyl-formamide; mineral oil at 90℃;
80%
Stage #1: (thiophen-3-yl)acetonitrile With potassium tert-butylate In 1,4-dioxane at 0℃; for 0.166667h;
Stage #2: methyl fluorobenzenedithiocarboxylate In 1,4-dioxane at 0 - 20℃; for 1h;
Stage #3: With iodine In 1,4-dioxane at 90℃;
77%

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