As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
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inquiryJinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pu
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inquiryhebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm
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inquiryUnique advantages for Moxifloxacin Cas 151096-09-2 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White crystalline powder Storage:Cool dry place Package:25kg/
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
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inquiryShanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
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inquiryOur advantages: 1. High quality and competitive price: 1) Standard: BP/USP/EP/ enterprise standard 2) All purity 鈮 9% 3) We are manufacturers and can provide high quality products at factory prices. 2. Fast and safe delivery 1) The package can
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
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inquiry1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W
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inquiry151096-09-2 Moxifloxacin product Name Moxifloxacin Synonyms (1'S,6'S)-1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-met
1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White crystal powder Storage:Store in sealed container
Cas:151096-09-2
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inquiryHenan Tianfu Chemical Co., Ltd. is located in Zhengzhou High-tech Development Zone with import and export license. We passed ISO 9001:2008 in 2009, and won "High-tech Enterprise" by provincial government in 2013.The objective of the com
Cas:151096-09-2
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inquiryWe have two GMP facilities in Hubei Province and cooperative factories in Zhejiang Province We are concentrating on the R&D and technical service of APIs and pharmaceutical intermediates Appearance:Light yellow or yellow powder or
1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
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inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
Cas:151096-09-2
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inquiryAbout Product Details Items Specifications Test Results Appearance White to white crystalline powde
Cas:151096-09-2
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inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:151096-09-2
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inquiryMoxifloxacin CAS:151096-09-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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inquiryHebei Mojin Biotechnology Co., Ltd,Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all em
Cas:151096-09-2
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inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
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inquiryProduct Name: Moxifloxacin Synonyms: MOXIFLOXACIN;Moxifloxacin EP Impurity;Moxifloxacin Hydrochloride 2;MOXIFLOXACIN HYDROCHELORIDE;(1'S,6'S)-1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihyd;(1'S,6
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inquiryTriumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw Mater
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inquiryOur company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-
Cas:151096-09-2
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inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:151096-09-2
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inquiryHubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other
Cas:151096-09-2
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
(1S,6S)-2,8-diazabicyclo[4.3.0]nonane
moxifloxacin
Conditions | Yield |
---|---|
With [BCl2(4-picoline)][AlCl4]; triethylamine In methanol at 85℃; for 6h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; | 96% |
In dimethyl sulfoxide at 65 - 70℃; for 6 - 8h; | 89.7% |
With triethylamine In N,N-dimethyl-formamide; acetonitrile at 0 - 78℃; for 11h; Reflux; | 66% |
moxifloxacin
Conditions | Yield |
---|---|
Stage #1: (4aS-cis)-1-cyclopropyl-7-(2,8 diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic aid-O3,O4-bis(propyloxy-O)borate. With hydrogenchloride In methanol; water at 10 - 15℃; for 2h; pH=1.0 - 2.0; Stage #2: With ammonia In water at 25 - 75℃; for 1.25h; pH=7.5 - 8; Product distribution / selectivity; | 90% |
Stage #1: (4aS-cis)-1-cyclopropyl-7-(2,8 diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic aid-O3,O4-bis(propyloxy-O)borate. With hydrogenchloride In methanol at 10 - 15℃; for 2h; pH=1 - 2; Stage #2: With ammonia In water at 25 - 75℃; pH=7.5 - 8; Product distribution / selectivity; | 90% |
1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
moxifloxacin
moxifloxacin
Conditions | Yield |
---|---|
Stage #1: (1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-(oxo-κO3)-3-quinolinecarboxylato-κO3)difluoroboron With methanol at 63 - 67℃; for 5 - 6h; Stage #2: With hydrogenchloride; sodium hydroxide; water at 50 - 60℃; for 2h; pH=8.0 - 12.0; Product distribution / selectivity; |
1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic acid-O3,O4-bis(propyloxy-O)borate
(1S,6S)-2,8-diazabicyclo[4.3.0]nonane
moxifloxacin
Conditions | Yield |
---|---|
Stage #1: 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline-carboxylic acid O3,O4-bis(propyloxy-O)borate; (1S,6S)-2,8-diazabicyclo[4.3.0]nonane With triethylamine In acetonitrile at 10 - 15℃; for 2h; Heating / reflux; Stage #2: With hydrogenchloride; water In methanol; acetonitrile at 10 - 15℃; for 2h; pH=1 - 2; Stage #3: With ammonia In water at 70 - 75℃; pH=7.5 - 9.0; Product distribution / selectivity; |
moxifloxacin hydrochloride
moxifloxacin
Conditions | Yield |
---|---|
With sodium hydroxide In water; acetone at 25 - 60℃; for 0.666667h; Product distribution / selectivity; | |
With sodium hydroxide In cyclohexane; water; acetone at 25 - 60℃; for 13.1667 - 15.1667h; Product distribution / selectivity; Heating / reflux; |
C25H33FN4O3
moxifloxacin
Conditions | Yield |
---|---|
Stage #1: C25H33FN4O3 With sodium hydroxide; water In ethylene glycol at 115℃; for 15h; Stage #2: With hydrogenchloride In water; ethylene glycol at 5℃; for 0.5h; pH=5.5; Product distribution / selectivity; |
C32H37FN4O5
moxifloxacin
Conditions | Yield |
---|---|
Stage #1: C32H37FN4O5 With sodium hydroxide; water In ethylene glycol at 115℃; for 15h; Stage #2: With hydrogenchloride In water; ethylene glycol at 5℃; for 0.5h; pH=5.5; Product distribution / selectivity; |
C30H41FN4O5
moxifloxacin
Conditions | Yield |
---|---|
Stage #1: C30H41FN4O5 With sodium hydroxide; water In ethylene glycol at 115℃; for 15h; Stage #2: With hydrogenchloride In water; ethylene glycol at 5℃; for 0.5h; pH=5.5; Product distribution / selectivity; |
C21H25FN4O3
moxifloxacin
Conditions | Yield |
---|---|
Stage #1: C21H25FN4O3 With sodium hydroxide; water In ethylene glycol at 115℃; for 15h; Stage #2: With hydrogenchloride In water; ethylene glycol at 5℃; for 0.5h; pH=5.5; Product distribution / selectivity; |
moxifloxacin
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In dichloromethane; water; isopropyl alcohol at 30 - 35℃; for 1h; | |
With sodium hydrogencarbonate In dichloromethane; water; isopropyl alcohol at 30 - 35℃; for 1h; |
moxifloxacin
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: lithium aluminium tetrahydride 2: Resolution of racemate 3: palladium on activated charcoal; hydrogen 4: Alkaline conditions View Scheme |
ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate
moxifloxacin
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sodium fluoride / N,N-dimethyl-formamide 2: Alkaline conditions View Scheme |
moxifloxacin
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: Resolution of racemate 2: palladium on activated charcoal; hydrogen 3: Alkaline conditions View Scheme |
B
moxifloxacin
Conditions | Yield |
---|---|
In aq. buffer at 24.84℃; pH=7.4; Equilibrium constant; |
1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
(1S,6S)-2,8-diazabicyclo[4.3.0]nonane
B
moxifloxacin
Conditions | Yield |
---|---|
With triethylamine In methanol at 85℃; for 6h; |
moxifloxacin
Conditions | Yield |
---|---|
With sodium cyanide In dimethyl sulfoxide at 100℃; for 17h; | 99% |
moxifloxacin
Conditions | Yield |
---|---|
In ethanol addn. of cerium compd. to ethanolic soln. of moxifloxacin, stirring for 1 d at 50°C; filtration, drying in vac. over CaCl2, elem. anal.; | 99% |
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 75 - 80℃; for 3h; | 98.08% |
In N,N-dimethyl-formamide at 25 - 80℃; for 13 - 16h; Product distribution / selectivity; | 90.2% |
carbonochloridic acid 1-chloro-ethyl ester
moxifloxacin
7-((4aS,7aS)-1-((1-chloroethoxy)carbonyl)octahydropyrrolo[3,4-b]pyridin-6-yl)-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylic acid
Conditions | Yield |
---|---|
With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In chloroform at 20℃; for 5h; Inert atmosphere; | 98% |
With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In chloroform at 20℃; for 5h; | 98% |
di-tert-butyl dicarbonate
moxifloxacin
7-((4aS,7aS)-1-(tert-butoxycarbonyl)-octahydropyrrolo-[3,4-b]pyridin-6-yl)-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylic acid
Conditions | Yield |
---|---|
With sodium hydroxide In tetrahydrofuran; water at 20℃; | 91% |
With sodium hydroxide In tetrahydrofuran; water at 20℃; | 91% |
With triethylamine In dichloromethane at 20℃; for 3h; |
Conditions | Yield |
---|---|
With sodium hydroxide In ethanol at 60 - 70℃; | 90% |
(2E)-but-2-enedioic acid
moxifloxacin
1-cyclopropyl-7-[(S,S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid fumarate
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 25 - 80℃; for 13 - 16h; | 89.2% |
Conditions | Yield |
---|---|
In ethanol addn. of yttrium compd. to ethanolic soln. of moxifloxacin, stirring for20 h at room temp.; filtration, drying in vac. over CaCl2, elem. anal.; | 86.67% |
N-(4-chlorophenyl)-2-iodoacetamide
moxifloxacin
Conditions | Yield |
---|---|
With triethylamine In acetonitrile for 12h; Reflux; | 85.02% |
Conditions | Yield |
---|---|
With sodium hydroxide In ethanol for 3h; Reflux; | 85% |
2-iodo-N-(p-fluorophenyl)acetamide
moxifloxacin
Conditions | Yield |
---|---|
With triethylamine In acetonitrile for 12h; Reflux; | 84.45% |
N-Jodacetyl-m-anisidid
moxifloxacin
Conditions | Yield |
---|---|
With triethylamine In acetonitrile for 12h; Reflux; | 84.3% |
methanol
moxifloxacin
methyl 1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid at 100℃; for 24h; | 83% |
Conditions | Yield |
---|---|
In methanol addn. of titanium compd. to methanolic soln. of moxifloxacin, stirring for 20 h at room temp.; filtration, drying in vac. over CaCl2, elem. anal.; | 82% |
Di-p-toluoyl-L-tartaric acid
moxifloxacin
1-cyclopropyl-7-[(S,S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid di-p-toluoyl-L-tartarate
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 25 - 80℃; for 13 - 16h; | 81.93% |
1,10-Phenanthroline
moxifloxacin
Conditions | Yield |
---|---|
With sodium hydroxide In ethanol for 3h; Reflux; | 81.5% |
1,10-Phenanthroline
moxifloxacin
Conditions | Yield |
---|---|
With sodium hydroxide In ethanol for 3h; Reflux; | 78.5% |
2-iodoacetanilide
moxifloxacin
Conditions | Yield |
---|---|
With triethylamine In acetonitrile for 12h; Reflux; | 78.4% |
Conditions | Yield |
---|---|
Stage #1: glycylglycine With oxovanadium(IV) sulfate; potassium hydroxide In methanol at 20℃; for 2h; Stage #2: moxifloxacin In methanol for 2h; Reflux; | 78% |
moxifloxacin
moxifloxacin hydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride In methanol at 0 - 5℃; for 1h; pH=1.0 - 2.0; Product distribution / selectivity; | 77% |
With hydrogenchloride; edetate disodium In methanol; water at 0 - 38℃; for 2h; | 54.84% |
With hydrogenchloride In ethanol at 0 - 10℃; for 2h; Product distribution / selectivity; |
1,10-Phenanthroline
moxifloxacin
Conditions | Yield |
---|---|
With sodium hydroxide In ethanol for 3h; Reflux; | 75.34% |
1,1'-carbonyldiimidazole
moxifloxacin
Conditions | Yield |
---|---|
In acetonitrile Reflux; Cooling with ice; | 75.3% |
1,2:3,4-di-O-isopropylidene-6-iodo-D-galactopyranose
moxifloxacin
1-cyclopropyl-7-[(4aS,7aS)-1-(6-deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactopyranos-6-yl)-octahydro-6H-pyrrolo[3,4-b]-pyridin-6-yl]-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
Conditions | Yield |
---|---|
With triethylamine In benzonitrile for 0.333333h; Microwave irradiation; | 75% |
Conditions | Yield |
---|---|
Stage #1: glycylleucine With oxovanadium(IV) sulfate; potassium hydroxide In methanol at 20℃; for 2h; Stage #2: moxifloxacin In methanol for 2h; Reflux; | 75% |
Conditions | Yield |
---|---|
In ethanol addn. of palladium compd. to ethanolic soln. of moxifloxacin, stirring for 20 h at room temp.; filtration, drying in vac. over CaCl2, elem. anal.; | 73.75% |
moxifloxacin
Conditions | Yield |
---|---|
With hydrogenchloride; disodium ethylenediaminetetraacetic acid In methanol; water at 0 - 38℃; for 2h; Product distribution / selectivity; | 72.43% |
Conditions | Yield |
---|---|
Stage #1: copper(II) acetate dihydrate; moxifloxacin In methanol at 20℃; for 0.5h; Stage #2: Fc-Phe In methanol for 2h; | 72% |
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