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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Methyl 2-(hydroxymethyl)acrylate

Cas:15484-46-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Methyl-2-(Hydroxymethyl)-Acrylate

Cas:15484-46-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-(Hydroxymethyl)-propenoic acid methyl ester

Cas:15484-46-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. High quality and competitive price: 1) Standard: BP/USP/EP/ enterprise standard 2) All purity ≥94% 3) We are manufacturers and can provide high quality products at factory prices. 2. Fast and safe delivery 1) The package c

Methyl 2-(hydroxymethyl)acrylate CAS:15484-46-5

Cas:15484-46-5

Min.Order:1 Kilogram

FOB Price: $245.0 / 255.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 15484-46-5 with competitive price

Cas:15484-46-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Methyl 2-(hydroxymethyl)acrylate/ LIDE PHARMA- Factory supply / Best price

Cas:15484-46-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Propenoic acid,2-(hydroxymethyl)-, methyl ester 15484-46-5

Cas:15484-46-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Methyl 2-(hydroxymethyl)acrylate CAS:15484-46-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

Methyl 2-(hydroxymethyl)acrylate CAS:15484-46-5

Cas:15484-46-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Propenoic acid,2-(hydroxymethyl)-, methyl ester

Cas:15484-46-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Propenoic acid,2-(hydroxymethyl)-, methyl ester

Cas:15484-46-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Methyl-2-(Hydroxymethyl)Acrylate(Telbivudine Intermediate)

Cas:15484-46-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Methyl 2-(hydroxymethyl)acrylate

Cas:15484-46-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Propenoic acid,2-(hydroxymethyl)-, methyl ester

Cas:15484-46-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products Methyl 2-(hydroxymethyl)acrylate

Cas:15484-46-5

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Methyl-2-(Hydroxymethyl)Acrylate(Telbivudine Intermediate)

Cas:15484-46-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Methyl 2-(hydroxymethyl)acrylate

Cas:15484-46-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Methyl 2-(hydroxymethyl)acrylate

Cas:15484-46-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Methyl 2-(hydroxymethyl)acrylate

Cas:15484-46-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Methyl 2-(hydroxymethyl)acrylate

Cas:15484-46-5

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Methyl 2-(hydroxymethyl)acrylate

Cas:15484-46-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

2-Propenoic acid,2-(hydroxymethyl)-, methyl ester

Cas:15484-46-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Methyl-2-(hydroxymethyl)acrylate cas no. 15484-46-5 98%

Cas:15484-46-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Methyl-2-(hydroxymethyl)acrylate

Cas:15484-46-5

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Methyl-2-(hydroxymethyl)acrylate

Cas:15484-46-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

Methyl-A-(Hydroxymethyl)Acrylate

Cas:15484-46-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Enterprise standard Application:Special building block

Methyl-2-(hydroxymethyl)-acrylate

Cas:15484-46-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Methyl 2-(hydroxymethyl)acrylate 100g

Cas:15484-46-5

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Methyl 2-(hydroxyMethyl)acrylate

Cas:15484-46-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Methyl-2-(Hydroxymethyl)Acrylate(Telbivudine Intermediate)

Cas:15484-46-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

Methyl-2-(hydroxymethyl)acrylate

Cas:15484-46-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

formaldehyd
50-00-0

formaldehyd

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane In 1,4-dioxane; water at 20℃; for 9h; Baylis-Hillman reaction;90%
With 1,4-diaza-bicyclo[2.2.2]octane In methanol at 20℃; for 9h; Baylis-Hillman reaction;90%
With 1,4-diaza-bicyclo[2.2.2]octane In 1,4-dioxane; water at 20℃; for 12h;90%
formaldehyd
50-00-0

formaldehyd

(methyloxycarbonylmethyl)triphenylphosphonium bromide
1779-58-4

(methyloxycarbonylmethyl)triphenylphosphonium bromide

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

Conditions
ConditionsYield
With potassium carbonate In water at 10 - 20℃; for 6h;85%
1,4-diaza-bicyclo[2.2.2]octane
280-57-9

1,4-diaza-bicyclo[2.2.2]octane

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

Conditions
ConditionsYield
With formaldehyd; paraformaldehyde In diethyl ether; nitrogen77%
formaldehyd
50-00-0

formaldehyd

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

Conditions
ConditionsYield
Stage #1: formaldehyd With phosphoric acid In water at 90℃; for 5h;
Stage #2: trimethyl phosphonoacetate With potassium carbonate In water at 35 - 40℃; for 0.9h;
62%
With potassium carbonate In water at 20℃; for 1h;55%
With potassium carbonate In water at 20℃; for 2h;44%
With potassium carbonate at 30 - 35℃; for 1h;
formaldehyd
50-00-0

formaldehyd

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

A

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

B

dimethyl 2,2′-[oxybis(methylene)]diacrylate
109669-53-6

dimethyl 2,2′-[oxybis(methylene)]diacrylate

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane at 95℃; for 4h;A 23%
B 60%
formaldehyd
50-00-0

formaldehyd

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

A

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

B

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate In water at 23℃;A 56%
B n/a
1,4-diaza-bicyclo[2.2.2]octane
280-57-9

1,4-diaza-bicyclo[2.2.2]octane

cyclohexanol formaldehyde hemiacetal

cyclohexanol formaldehyde hemiacetal

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

Conditions
ConditionsYield
In cyclohexanol45%
formaldehyd
50-00-0

formaldehyd

ethyl acrylate
140-88-5

ethyl acrylate

A

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

B

dimethyl 2,2′-[oxybis(methylene)]diacrylate
109669-53-6

dimethyl 2,2′-[oxybis(methylene)]diacrylate

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane for 19h; Heating;A n/a
B 13%
2-acetoxymethyl-acrylic acid
89533-83-5

2-acetoxymethyl-acrylic acid

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

Conditions
ConditionsYield
With methanol; sulfuric acid
methanol
67-56-1

methanol

propargyl alcohol
107-19-7

propargyl alcohol

tetracarbonyl nickel
13463-39-3, 71564-36-8

tetracarbonyl nickel

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

Conditions
ConditionsYield
(i) AcOH, (ii) /BRN= 506003/, (iii) H2SO4; Multistep reaction;
methanol
67-56-1

methanol

ethyl 2-(hydroxymethyl)acrylate
10029-04-6

ethyl 2-(hydroxymethyl)acrylate

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

Conditions
ConditionsYield
With potassium carbonate at 20℃; for 4h;
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

propargyl alcohol
107-19-7

propargyl alcohol

A

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

B

methyl α-methoxymethylacrylate
25328-81-8

methyl α-methoxymethylacrylate

Conditions
ConditionsYield
With methanesulfonic acid; palladium diacetate; diphenyl-(6-methyl-pyridin-2-yl)phosphine In 1,2-dichloro-ethane at 50℃; under 22801.5 Torr; for 3h; Catalytic behavior; Inert atmosphere; Schlenk technique; Autoclave; regioselective reaction;A 23.8 %Chromat.
B 71.4 %Chromat.
methanol
67-56-1

methanol

propargyl alcohol
107-19-7

propargyl alcohol

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

Conditions
ConditionsYield
With methanesulfonic acid; palladium diacetate; diphenyl-(6-methyl-pyridin-2-yl)phosphine In 1,2-dichloro-ethane at 50℃; under 22801.5 Torr; for 3h; Catalytic behavior; Temperature; Pressure; Solvent; Inert atmosphere; Schlenk technique; Autoclave; regioselective reaction;95.2 %Chromat.
methanol
67-56-1

methanol

propargyl alcohol
107-19-7

propargyl alcohol

A

methyl 4-hydroxy-2-butenoate
29576-13-4

methyl 4-hydroxy-2-butenoate

B

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

C

methyl α-methoxymethylacrylate
25328-81-8

methyl α-methoxymethylacrylate

Conditions
ConditionsYield
With methanesulfonic acid; palladium diacetate; diphenyl-(6-methyl-pyridin-2-yl)phosphine In 1,2-dichloro-ethane at 60℃; under 22801.5 Torr; for 20h; Catalytic behavior; Inert atmosphere; Schlenk technique; Autoclave; regioselective reaction;A 6.1 %Chromat.
B 21.6 %Chromat.
C 72.2 %Chromat.
With methanesulfonic acid; palladium diacetate; diphenyl-(6-methyl-pyridin-2-yl)phosphine In 1,2-dichloro-ethane at 60℃; under 22801.5 Torr; for 3h; Catalytic behavior; Inert atmosphere; Schlenk technique; Autoclave; regioselective reaction;A 5.9 %Chromat.
B 85.6 %Chromat.
C 8.5 %Chromat.
methanol
67-56-1

methanol

propargyl alcohol
107-19-7

propargyl alcohol

A

methyl 4-hydroxy-2-butenoate
29576-13-4

methyl 4-hydroxy-2-butenoate

B

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

Conditions
ConditionsYield
With methanesulfonic acid; palladium diacetate; diphenyl-(6-methyl-pyridin-2-yl)phosphine In 1,2-dichloro-ethane at 50℃; under 22801.5 Torr; for 3h; Catalytic behavior; Inert atmosphere; Schlenk technique; Autoclave; regioselective reaction;A 5.3 %Chromat.
B 94.7 %Chromat.
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

acetyl chloride
75-36-5

acetyl chloride

methyl 2-(1-acetoxymethyl)acrylate
30982-08-2

methyl 2-(1-acetoxymethyl)acrylate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 18h; Schlenk technique; Inert atmosphere;100%
With pyridine In dichloromethane at -12 - 20℃; for 3h; Inert atmosphere;85%
With triethylamine In dichloromethane at 0 - 20℃;71%
With pyridine In diethyl ether at 20℃; for 0.5h; Inert atmosphere;44%
With pyridine In dichloromethane at 0 - 20℃; for 24h;
triethylsilyl chloride
994-30-9

triethylsilyl chloride

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

C11H22O3Si
1189797-29-2

C11H22O3Si

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane100%
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

dimethyl 3,3'-oxy(2E,2'E)-bis(2-methylacrylate)

dimethyl 3,3'-oxy(2E,2'E)-bis(2-methylacrylate)

Conditions
ConditionsYield
With Co(dmgBF2)2(THF)2; hydrogen In benzene at 50℃; for 24h;100%
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

methyl 3-hydroxy-2-methylpropanoate
64809-29-6

methyl 3-hydroxy-2-methylpropanoate

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In ethyl acetate at 20℃;97%
With bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; N(1)-(4-butylphenyl)-N(2)-(4-((11bS)-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yloxy)phenyl)phthalamide; hydrogen In dichloromethane at 20℃; under 37503.8 Torr; for 20h; Autoclave;
With bis(norbornadiene)rhodium(l)tetrafluoroborate; C50H44N3O2P; C112H112N8O8Zn; hydrogen In dichloromethane at 25℃; under 7500.75 Torr; for 16h;
With bis(norbornadiene)rhodium(l)tetrafluoroborate; C6H15N*C27H29F3NO4PSSi2; C27H26NO4P; hydrogen In dichloromethane under 15001.5 Torr; for 18h; Reagent/catalyst; enantioselective reaction;n/a
With palladium 10% on activated carbon; hydrogen; potassium carbonate In methanol at 20℃; under 760.051 Torr; for 7h;
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

tert-butylchlorodiphenylsilane
58479-61-1

tert-butylchlorodiphenylsilane

methyl 2-(((tert-butyldiphenylsilyl)oxy)methyl)acrylate

methyl 2-(((tert-butyldiphenylsilyl)oxy)methyl)acrylate

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 0 - 20℃; for 1h;97%
In N,N-dimethyl-formamide at 0 - 20℃; for 19h;89%
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃; for 16h;87%
(5-methyl-pyridin-2-yl)amine
1603-41-4

(5-methyl-pyridin-2-yl)amine

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

3,7-dimethyl-2H-pyrido[1,2-a]pyrimidin-2-one

3,7-dimethyl-2H-pyrido[1,2-a]pyrimidin-2-one

Conditions
ConditionsYield
With 1,1,1,3',3',3'-hexafluoro-propanol Reflux;95%
With N-heterocyclic carbene palladium(II) complex supported on fibrous nanosilica In trifluoroacetic acid for 1h; Reflux; Green chemistry; chemoselective reaction;
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

acryloyl chloride
814-68-6

acryloyl chloride

2-acryloyloxymethyl-acrylic acid methyl ester

2-acryloyloxymethyl-acrylic acid methyl ester

Conditions
ConditionsYield
With triethylamine92%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

methyl 2-trimethylsilyloxymethylacrylate
1158177-66-2

methyl 2-trimethylsilyloxymethylacrylate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;92%
3-methylpyridin-2-ylamine
1603-40-3

3-methylpyridin-2-ylamine

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

3,9-dimethyl-2H-pyrido[1,2-a]pyrimidin-2-one

3,9-dimethyl-2H-pyrido[1,2-a]pyrimidin-2-one

Conditions
ConditionsYield
With 1,1,1,3',3',3'-hexafluoro-propanol Reflux;92%
With N-heterocyclic carbene palladium(II) complex supported on fibrous nanosilica In trifluoroacetic acid for 1h; Reflux; Green chemistry; chemoselective reaction;
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

2-(tert-butyl-dimethyl-silanyloxymethyl)-acrylic acid methyl ester
144828-45-5

2-(tert-butyl-dimethyl-silanyloxymethyl)-acrylic acid methyl ester

Conditions
ConditionsYield
With dmap; TEA In dichloromethane at 0 - 20℃;91%
With 1H-imidazole In N,N-dimethyl-formamide at 0℃; Inert atmosphere;82%
With dmap; triethylamine In dichloromethane at 0 - 20℃; Sealed tube; Inert atmosphere;81%
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

benzylamine
100-46-9

benzylamine

methyl 2-[(N-benzylamino)methyl]-3-hydroxypropanoate
1023326-56-8

methyl 2-[(N-benzylamino)methyl]-3-hydroxypropanoate

Conditions
ConditionsYield
In methanol at 20℃; for 16h;91%
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

Tosyl isocyanate
4083-64-1

Tosyl isocyanate

C13H15NO6S

C13H15NO6S

Conditions
ConditionsYield
In dichloromethane at 0℃;91%
2-aminopyridine
504-29-0

2-aminopyridine

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

3-methyl-2H-pyrido[1,2-a]pyrimidin-2-one
1390649-05-4

3-methyl-2H-pyrido[1,2-a]pyrimidin-2-one

Conditions
ConditionsYield
With 1,1,1,3',3',3'-hexafluoro-propanol for 12h; Reflux;90%
With N-heterocyclic carbene palladium(II) complex supported on fibrous nanosilica In trifluoroacetic acid for 1h; Solvent; Reagent/catalyst; Reflux; Green chemistry; chemoselective reaction;
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

methyl 2-(bromomethyl)propenoate
4224-69-5

methyl 2-(bromomethyl)propenoate

Conditions
ConditionsYield
With phosphorus tribromide In diethyl ether Inert atmosphere;89%
With phosphorus tribromide In diethyl ether at 0 - 20℃; for 2h;87.4%
With phosphorus tribromide In acetonitrile at 20℃; for 4h;86%
dimethylsulfide
75-18-3

dimethylsulfide

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

methyl 2-(bromomethyl)propenoate
4224-69-5

methyl 2-(bromomethyl)propenoate

Conditions
ConditionsYield
With N-Bromosuccinimide; sodium chloride In diethyl ether; dichloromethane89%
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

N-benzyloxy-α-methyl-α-bromopropionamide
1303507-75-6

N-benzyloxy-α-methyl-α-bromopropionamide

methyl 2-(((1-((benzyloxy)amino)-2-methyl-1-oxopropan-2-yl)-oxy)methyl)acrylate

methyl 2-(((1-((benzyloxy)amino)-2-methyl-1-oxopropan-2-yl)-oxy)methyl)acrylate

Conditions
ConditionsYield
With sodium carbonate at 20℃; for 3h; Inert atmosphere;89%
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

3-hydroxy-(2S)-methylpropionate
80657-57-4

3-hydroxy-(2S)-methylpropionate

Conditions
ConditionsYield
With diisopropyl{1-[(S)-3,5-dioxa-4-phospha-cyclohepta(2,1-a;3,4-a')dinaphthalen-4-yl]-3-methyl-2-indolyl}phosphine; bis(norbornadiene)rhodium(l)tetrafluoroborate; hydrogen In dichloromethane at -40℃; under 15001.5 Torr; for 15h; Reactivity; Pressure; Temperature; Concentration; Inert atmosphere; optical yield given as %ee; enantioselective reaction;87%
With N-methyl-N-{(S)-1-[2-(diphenylphosphino)phenyl]ethyl}-(S)-1,10-bi-2-naphthylphosphoramidite; bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; hydrogen In dichloromethane at 20℃; under 7500.75 Torr; for 24h; optical yield given as %ee;
With BF4(1-)*C8H10Rh(1+)*C17H27NO2P2; hydrogen In dichloromethane at 25℃; under 750.075 Torr; for 1.5h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

diethylazodicarboxylate
1972-28-7

diethylazodicarboxylate

C11H18N2O6

C11H18N2O6

Conditions
ConditionsYield
With triphenylphosphine In dichloromethane at 0 - 20℃; for 0.216667h; Mitsunobu Displacement; Inert atmosphere; Schlenk technique; stereoselective reaction;87%
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

2-(hydroxymethyl)acrylic acid
4370-80-3

2-(hydroxymethyl)acrylic acid

Conditions
ConditionsYield
With methanol; potassium hydroxide In tetrahydrofuran; water at 20℃; for 24h;85%
triisopropylsilyl chloride
13154-24-0

triisopropylsilyl chloride

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

methyl 2-(((triisopropylsilyl)oxy)methyl)acrylate
1187192-35-3

methyl 2-(((triisopropylsilyl)oxy)methyl)acrylate

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 0 - 20℃; for 1h;85%
With 1H-imidazole; dmap In dichloromethane at 20℃; for 18h; Inert atmosphere;123.3 mg
With 1H-imidazole In dichloromethane Inert atmosphere;
2-amino-5-iodopyridine
20511-12-0

2-amino-5-iodopyridine

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

7-iodo-3-methyl-2H-pyrido[1,2-a]pyrimidin-2-one

7-iodo-3-methyl-2H-pyrido[1,2-a]pyrimidin-2-one

Conditions
ConditionsYield
With 1,1,1,3',3',3'-hexafluoro-propanol Reflux;85%
With N-heterocyclic carbene palladium(II) complex supported on fibrous nanosilica In trifluoroacetic acid for 1h; Reflux; Green chemistry; chemoselective reaction;
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

2-chloro-1,1,1-trimethoxyethane
74974-54-2

2-chloro-1,1,1-trimethoxyethane

dimethyl 2-chloro-4-methylenepentanedioate

dimethyl 2-chloro-4-methylenepentanedioate

Conditions
ConditionsYield
With acetic acid In toluene at 130℃; for 24h;85%
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

Cinnamyl bromide
4392-24-9

Cinnamyl bromide

methyl (E)-2-((cinnamyloxy)methyl)acrylate

methyl (E)-2-((cinnamyloxy)methyl)acrylate

Conditions
ConditionsYield
Stage #1: methyl 2-hydroxymethylacrylate With sodium hydride In tetrahydrofuran at 0 - 20℃; Inert atmosphere; Schlenk technique;
Stage #2: Cinnamyl bromide In tetrahydrofuran at 20℃; Inert atmosphere; Schlenk technique;
84%
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

3-fluoropyridin-2-amine
21717-95-3

3-fluoropyridin-2-amine

9-fluoro-3-methyl-2H-pyrido[1,2-a]pyrimidin-2-one

9-fluoro-3-methyl-2H-pyrido[1,2-a]pyrimidin-2-one

Conditions
ConditionsYield
With 1,1,1,3',3',3'-hexafluoro-propanol Reflux;83%
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

3-bromo-5-methylpyridin-2-amine
17282-00-7

3-bromo-5-methylpyridin-2-amine

9-bromo-3,7-dimethyl-2H-pyrido[1,2-a]pyrimidin-2-one

9-bromo-3,7-dimethyl-2H-pyrido[1,2-a]pyrimidin-2-one

Conditions
ConditionsYield
With 1,1,1,3',3',3'-hexafluoro-propanol Reflux;83%
cyclopentadienyl titanium(IV) trichloride
1270-98-0

cyclopentadienyl titanium(IV) trichloride

methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

(2-carbethoxyprop-2-enoxy)bischloro-η5-cyclopentadienyl titanium(IV)
153091-07-7

(2-carbethoxyprop-2-enoxy)bischloro-η5-cyclopentadienyl titanium(IV)

Conditions
ConditionsYield
With triethylamine In benzene (Ar); stirring (2 h); evapn. (vac.), sublimation (80°C, 0.01 Torr), recrystn. (toluene/hexanes); elem. anal.;82%
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

4-nitro-benzoyl chloride
122-04-3

4-nitro-benzoyl chloride

4-nitrobenzoic acid 2-methoxycarbonyl-allyl ester
1107635-38-0

4-nitrobenzoic acid 2-methoxycarbonyl-allyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 0.75h;81%
methyl 2-hydroxymethylacrylate
15484-46-5

methyl 2-hydroxymethylacrylate

(E)-3,5-hexadienoic acid
32775-95-4

(E)-3,5-hexadienoic acid

(E)-Hexa-3,5-dienoic acid 2-methoxycarbonyl-allyl ester
81095-98-9

(E)-Hexa-3,5-dienoic acid 2-methoxycarbonyl-allyl ester

Conditions
ConditionsYield
With pyridine; dicyclohexyl-carbodiimide In diethyl ether at 0℃; for 12h;78%

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