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HANGZHOU YUNUO CHEMICAL CO.,LTD

Hangzhou Yunuo Chemical Co., Ltd is located in Hangzhou city China. As a global supplier in the chemical industry, Yunuochem is to create added value for customers around the world. Sticking to such business idea of "Good faith wins the busine

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid

Cas:189005-44-5

Min.Order:10 Gram

Negotiable

Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid

Cas:189005-44-5

Min.Order:0

Negotiable

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid Manufacturer/High quality/Best price/In stock

Cas:189005-44-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Zolpidic acid

Cas:189005-44-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED intermediates (Fluorene,Carbazole,Boric acid...) 4.Customs Synthesis

Tianfu Chem 6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid

Cas:189005-44-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid CAS 189005-44-5

Cas:189005-44-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 189005-44-5 with competitive price

Cas:189005-44-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid 189005-44-5

Cas:189005-44-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid CAS:189005-44-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermedia

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid CAS:189005-44-5

Cas:189005-44-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid

Cas:189005-44-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:189005-44-5

Cas:189005-44-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid

Cas:189005-44-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Zolpidic Acid

Cas:189005-44-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

189005-44-5 6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid/ high quality /Best price/In stock

Cas:189005-44-5

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best Offer6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid

Cas:189005-44-5

Min.Order:0

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

189005-44-5 6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid/ high quality /Best price/In stock

Cas:189005-44-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid

Cas:189005-44-5

Min.Order:0

Negotiable

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid

Cas:189005-44-5

Min.Order:1 Kilogram

Negotiable

Type:Other

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid

Cas:189005-44-5

Min.Order:0

Negotiable

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

Best price Zolpidic Acid 189005-44-5

Cas:189005-44-5

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

6-Methyl-2-(4-Methylphenyl)Imidazol[1,2-A]-Pyridine-3-Acetic Acid

Cas:189005-44-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid 5g

Cas:189005-44-5

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid

Cas:189005-44-5

Min.Order:0

Negotiable

Type:Manufacturers

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Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid

Cas:189005-44-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Synthetic route

ethyl 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetate
193979-47-4

ethyl 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetate

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
With water; potassium hydroxide In ethanol at 30℃;96%
With sodium hydroxide In water for 3h; Reflux;81.8%
With water; sodium hydroxide In ethanol at 90℃; Flow reactor;
N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide
82626-48-0

N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
With hydrogenchloride In water at 0℃; for 18h; Heating / reflux;94%
oxalyl dichloride
79-37-8

oxalyl dichloride

6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyridine
88965-00-8

6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyridine

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Stage #1: oxalyl dichloride; 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyridine With potassium carbonate In tetrahydrofuran at 20 - 35℃;
Stage #2: With potassium hydroxide In tetrahydrofuran; water at 65 - 70℃;
Stage #3: With hydrazine hydrate In water at 110 - 115℃; Reagent/catalyst; Temperature; Solvent;
95.2%
(5-methyl-pyridin-2-yl)amine
1603-41-4

(5-methyl-pyridin-2-yl)amine

3-bromo-4-(4-methylphenyl)-4-oxobutanoic acid
53515-23-4

3-bromo-4-(4-methylphenyl)-4-oxobutanoic acid

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
With sodium carbonate In water at 60℃; for 6h; Concentration; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;82%
(5-methyl-pyridin-2-yl)amine
1603-41-4

(5-methyl-pyridin-2-yl)amine

3-chloro-4-(4-methylphenyl)-4-oxobutanoic acid
68261-97-2

3-chloro-4-(4-methylphenyl)-4-oxobutanoic acid

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
With sodium carbonate In water at 80℃; for 7h; Concentration; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;52%
6-methyl-3-cyanomethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine
768398-03-4

6-methyl-3-cyanomethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
With hydrogenchloride; water91%
Stage #1: 6-methyl-3-cyanomethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine With sulfuric acid; water at 110℃; for 4 - 5h;
Stage #2: With sodium hydroxide; water at 0℃; pH=9;
Stage #3: With water; acetic acid pH=5.5; Product distribution / selectivity;
72%
Stage #1: 6-methyl-3-cyanomethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine With hydrogenchloride In water at 25 - 100℃; for 12h; Heating / reflux;
Stage #2: With potassium hydroxide In water at 25 - 105℃; for 2 - 3h;
Stage #3: With acetic acid In water at 30 - 40℃;
Stage #1: 6-methyl-3-cyanomethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine With sodium hydroxide; water at 55 - 98℃; for 16.5h; Heating / reflux;
Stage #2: With acetic acid In water at 25℃; for 4h; pH=5.3;
With sulfuric acid at 110℃; Inert atmosphere;
(6-methyl-2-p-tolyl-2,3-dihydro-imidazo[1,2-a]pyridin-3-yl)-oxoacetic acid
927820-48-2

(6-methyl-2-p-tolyl-2,3-dihydro-imidazo[1,2-a]pyridin-3-yl)-oxoacetic acid

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Stage #1: (6-methyl-2-p-tolyl-2,3-dihydro-imidazo[1,2-a]pyridin-3-yl)-oxoacetic acid With potassium hydroxide; hydrazine In diethylene glycol at 120 - 180℃; pH=4 - 5;
Stage #2: With acetic acid In water; diethylene glycol at 0 - 10℃; pH=6 - 6.5;
potassium 2-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)acetate

potassium 2-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)acetate

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
With acetic acid In water; acetone at 0 - 10℃; for 0.5h;67%
6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyridine
88965-00-8

6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyridine

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 78 percent / acetic acid / H2O / 4 h / 50 - 55 °C
2.1: MeI / ethanol / 24 h / 20 °C
2.2: H2O; ethanol / 4 h / Heating
3.1: 87 percent / aq. KOH / ethanol / 8 h / Heating
View Scheme
Multi-step reaction with 4 steps
1: 79 percent / AcOH
4: 91 percent / H2O, HCl
View Scheme
Multi-step reaction with 2 steps
1: ferrocene; bis(1-methyl-1-phenylethyl)peroxide / 20 h / 20 - 100 °C / Inert atmosphere; Sealed tube
2: sulfuric acid / 110 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: tris(bipyridine)ruthenium(II) dichloride hexahydrate / methanol; water / 36 h / 20 °C / Irradiation; Inert atmosphere
2: potassium hydroxide / water; ethanol / 30 °C
View Scheme
Multi-step reaction with 2 steps
1: rhodium (II) octanoate dimer / chloroform / 4 h / 20 °C / Inert atmosphere
2: lithium hydroxide monohydrate / methanol; water / 1 h / 20 °C
View Scheme
2-(4-methylphenyl)-6-methylimidazo[1,2-α]pyridine-3-acetamide
365213-58-7

2-(4-methylphenyl)-6-methylimidazo[1,2-α]pyridine-3-acetamide

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
With potassium hydroxide In ethanol for 8h; Heating;87%
(5-methyl-pyridin-2-yl)amine
1603-41-4

(5-methyl-pyridin-2-yl)amine

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: methanol / 0.33 h / 30 °C
2: water; potassium hydroxide / ethanol / 30 °C
View Scheme
Multi-step reaction with 3 steps
1: sodium hydrogencarbonate / ethanol / 6 h / 20 °C / Inert atmosphere
2: ferrocene; bis(1-methyl-1-phenylethyl)peroxide / 20 h / 20 - 100 °C / Inert atmosphere; Sealed tube
3: sulfuric acid / 110 °C / Inert atmosphere
View Scheme
Multi-step reaction with 4 steps
1: diethyl ether / 1 h / 0 °C
2: copper(l) chloride / toluene / 1 h / Inert atmosphere; Reflux
3: pyrographite / ethanol / 20 °C
4: acetic acid / water; acetone / 0.5 h / 0 - 10 °C
View Scheme
C21H20N2O4

C21H20N2O4

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
With acetic acid for 4h; Reflux;560 mg
C15H17NO6
1381932-38-2

C15H17NO6

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: methanol / 0.33 h / 30 °C
2: water; potassium hydroxide / ethanol / 30 °C
View Scheme
C13H15NO5

C13H15NO5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: pyridine / dichloromethane / 0.5 h / 0 °C
2: methanol / 0.33 h / 30 °C
3: water; potassium hydroxide / ethanol / 30 °C
View Scheme
4-methyl-β-nitrostyrene
7559-36-6

4-methyl-β-nitrostyrene

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: dmap / acetonitrile / 30 °C
2: pyridine / dichloromethane / 0.5 h / 0 °C
3: methanol / 0.33 h / 30 °C
4: water; potassium hydroxide / ethanol / 30 °C
View Scheme
4-(bromoacetyl)toluene
619-41-0

4-(bromoacetyl)toluene

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium hydrogencarbonate / ethanol / 6 h / 20 °C / Inert atmosphere
2: ferrocene; bis(1-methyl-1-phenylethyl)peroxide / 20 h / 20 - 100 °C / Inert atmosphere; Sealed tube
3: sulfuric acid / 110 °C / Inert atmosphere
View Scheme
dimethyl-(6-methyl-2-p-tolylimidazo[1,2-a]pyridin-3-ylmethyl)-amine
106961-33-5

dimethyl-(6-methyl-2-p-tolylimidazo[1,2-a]pyridin-3-ylmethyl)-amine

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: MeI / ethanol / 24 h / 20 °C
1.2: H2O; ethanol / 4 h / Heating
2.1: 87 percent / aq. KOH / ethanol / 8 h / Heating
View Scheme
Multi-step reaction with 3 steps
3: 91 percent / H2O, HCl
View Scheme
para-methylacetophenone
122-00-9

para-methylacetophenone

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: polymer supported sulfonic acid resin / toluene / 120 °C / Flow reactor
2: tetrafluoroboric acid diethyl ether / acetonitrile / 120 °C / Flow reactor
3: sodium hydroxide; water / ethanol / 90 °C / Flow reactor
View Scheme
6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrafluoroboric acid diethyl ether / acetonitrile / 120 °C / Flow reactor
2: sodium hydroxide; water / ethanol / 90 °C / Flow reactor
View Scheme
4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: diethyl ether / 1 h / 0 °C
2: copper(l) chloride / toluene / 1 h / Inert atmosphere; Reflux
3: pyrographite / ethanol / 20 °C
4: acetic acid / water; acetone / 0.5 h / 0 - 10 °C
View Scheme
5-methyl-N-(4-methylbenzylidene)pyridin-2-amine

5-methyl-N-(4-methylbenzylidene)pyridin-2-amine

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: copper(l) chloride / toluene / 1 h / Inert atmosphere; Reflux
2: pyrographite / ethanol / 20 °C
3: acetic acid / water; acetone / 0.5 h / 0 - 10 °C
View Scheme
toluene
108-88-3

toluene

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: aluminum (III) chloride / 1,2-dichloro-ethane / 4 h / 0 - 20 °C
2: hydrogen iodide; toluene-4-sulfonic acid / 5,5-dimethyl-1,3-cyclohexadiene; ethanol / 3 h / 110 - 120 °C
3: sodium carbonate / water / 20 °C
4: sodium hydroxide / water / 3 h / Reflux
View Scheme
4-(p-methylphenyl)-4-oxo-2-butenoic acid
20972-36-5, 35513-41-8, 24849-45-4

4-(p-methylphenyl)-4-oxo-2-butenoic acid

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrogen iodide; toluene-4-sulfonic acid / 5,5-dimethyl-1,3-cyclohexadiene; ethanol / 3 h / 110 - 120 °C
2: sodium carbonate / water / 20 °C
3: sodium hydroxide / water / 3 h / Reflux
View Scheme
(5-methyl-pyridin-2-yl)amine
1603-41-4

(5-methyl-pyridin-2-yl)amine

2,2-dihydroxy-1-(p-tolyl)ethanone
16208-14-3

2,2-dihydroxy-1-(p-tolyl)ethanone

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetonitrile / 4 h / Reflux
2: acetic acid / 4 h / Reflux
View Scheme
Trimethyl-(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-ylmethyl)-ammonium; iodide
106961-34-6

Trimethyl-(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-ylmethyl)-ammonium; iodide

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: 91 percent / H2O, HCl
View Scheme
6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetyl chloride hydrochloride
851972-87-7

(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetyl chloride hydrochloride

Conditions
ConditionsYield
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 0℃; for 3h;100%
N,N-dimethylammonium chloride
506-59-2

N,N-dimethylammonium chloride

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide
82626-48-0

N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In N,N-dimethyl acetamide at 90 - 100℃; for 3h; Solvent; Reagent/catalyst; Temperature;95.6%
methanol
67-56-1

methanol

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

methyl 2-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)acetate
258273-50-6

methyl 2-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)acetate

Conditions
ConditionsYield
Stage #1: methanol; 6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid; sulfuric acid at 5 - 20℃; for 4h; Heating / reflux;
Stage #2: With sodium carbonate In water pH=8; Product distribution / selectivity;
93.3%
toluene-4-sulfonic acid for 6h; Product distribution / selectivity; Heating / reflux;75.6%
Stage #1: methanol; 6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid; hydrogenchloride for 8h; Heating / reflux;
Stage #2: With sodium hydrogencarbonate In water pH=7; Product distribution / selectivity;
71.5%
hydrogenchloride In water for 5h; Product distribution / selectivity; Heating / reflux;
Stage #1: methanol; 6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid; sulfuric acid In toluene for 4h; Heating / reflux;
Stage #2: With sodium hydrogencarbonate In water pH=7; Product distribution / selectivity;
6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

2-(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-ethanol
851972-89-9

2-(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-ethanol

Conditions
ConditionsYield
With borane-THF In tetrahydrofuran at 0 - 20℃; for 2h;93%
6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

dimethyl amine
124-40-3

dimethyl amine

N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide
82626-48-0

N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide

Conditions
ConditionsYield
Stage #1: 6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid With pivaloyl chloride; triethylamine In dichloromethane at 0 - 5℃; for 0.5h;
Stage #2: dimethyl amine In dichloromethane; water at 0 - 5℃; for 0.5h;
84.3%
Stage #1: 6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid With phosphorus pentachloride In dichloromethane at 20 - 35℃; for 24h;
Stage #2: dimethyl amine In dichloromethane at 20℃; for 24h;
56%
In tetrahydrofuran at 20℃; for 1h;
benzyl bromide
100-39-0

benzyl bromide

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

benzyl-[6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyridine-3-yl]-acetate

benzyl-[6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyridine-3-yl]-acetate

Conditions
ConditionsYield
With sodium hydroxide In water for 1.5h; Heating / reflux;71%
oxalyl dichloride
79-37-8

oxalyl dichloride

N,N-dimethylammonium chloride
506-59-2

N,N-dimethylammonium chloride

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

pyrographite
7440-44-0

pyrographite

tartaric acid
87-69-4

tartaric acid

zolpidem tartrate

zolpidem tartrate

Conditions
ConditionsYield
With triethylamine In methanol; dichloromethane; water70.1%
With triethylamine In methanol; dichloromethane; water70.1%
N,N-dimethylammonium chloride
506-59-2

N,N-dimethylammonium chloride

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

pyrographite
7440-44-0

pyrographite

tartaric acid
87-69-4

tartaric acid

zolpidem tartrate

zolpidem tartrate

Conditions
ConditionsYield
With thionyl chloride; triethylamine In methanol; dichloromethane; water65.2%
With thionyl chloride; triethylamine In methanol; dichloromethane; water65.2%
N-methyl-N-allylamine
627-37-2

N-methyl-N-allylamine

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

N-allyl-N-methyl-2-(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetamide
851973-02-9

N-allyl-N-methyl-2-(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetamide

Conditions
ConditionsYield
With bis(2-oxo-1,3-oxazolidin-3-yl)phosphinous chloride; triethylamine In dichloromethane at 20℃;60%
6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

1,1'-carbonyldiimidazole
530-62-1

1,1'-carbonyldiimidazole

1-Imidazol-1-yl-2-(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-ethanone

1-Imidazol-1-yl-2-(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-ethanone

1-hydroxy-pyrrolidine-2,5-dione
6066-82-6

1-hydroxy-pyrrolidine-2,5-dione

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

(6-Methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester

(6-Methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In N,N-dimethyl-formamide for 14h; Ambient temperature;
6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

N,N-didemethylzolpidem-N-{2-[3-(p-hydroxyphenyl)]methyl propionate}
189005-45-6

N,N-didemethylzolpidem-N-{2-[3-(p-hydroxyphenyl)]methyl propionate}

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: DCC / dimethylformamide / 14 h / Ambient temperature
2: dimethylformamide / 0.25 h / Ambient temperature
View Scheme
6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

N,N-didemethylzolpidem-N-{2-[3-(4-hydroxy-3-iodophenyl)]methyl propionate}

N,N-didemethylzolpidem-N-{2-[3-(4-hydroxy-3-iodophenyl)]methyl propionate}

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: DCC / dimethylformamide / 14 h / Ambient temperature
2: dimethylformamide / 0.25 h / Ambient temperature
3: NaI, chloramine T / methanol; H2O / 0.17 h / 0 °C
View Scheme
6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide
82626-48-0

N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide

pivaloyl chloride
3282-30-2

pivaloyl chloride

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid
189005-44-5

6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid

C22H24N2O3

C22H24N2O3

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 15℃;

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