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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Tetrahydro-4-pyranol Manufacturer/High quality/Best price/In stock

Cas:2081-44-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-Hydroxytetrahydropyran supplier in China

Cas:2081-44-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

High quality Tetrahydro-4-pyranol Cas 2081-44-9 with steady supply Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed ad

High quality Tetrahydro-4-pyranol Cas 2081-44-9 with steady supply

Cas:2081-44-9

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Tetrahydro-4H-pyran-4-ol

Cas:2081-44-9

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Tetrahydro-4H-pyran-4-ol

Cas:2081-44-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/1149.html Product Name Tetrahydro-4-pyranol CAS No. 2081-44-9

Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

Tetrahydro-4-pyranol CAS:2081-44-9

Cas:2081-44-9

Min.Order:1 Kilogram

FOB Price: $1.5 / 3.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU CHEM-Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 2081-44-9 with competitive price

Cas:2081-44-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name: Tetrahydro-4-pyranol Synonyms: 2H-PYRAN-4-OL, TETRAHYDRO;4-HYDROXYTETRAHYDROPYRAN;TETRAHYDRO-2H-PYRAN-4-OL;TETRAHYDRO-4H-PYRAN-4-OL;TETRAHYDRO-4-PYRANOL;Tetrahydropyran-4-ol;POH;4-HYDROXYTETRA

Tetrahydro-4-pyranol CAS: 2081-44-9

Cas:2081-44-9

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Tetrahydro-4-pyranol 2081-44-9

Cas:2081-44-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: Tetrahydro-4-pyranol CAS: 2081-44-9 MF: C5H10O2 MW: 102.13 EINECS: 218-210-8 Mol File: 2081-44-9.mol Tetrahydro-4-pyranol Structure Tetrahydro-4-pyranol Chemical Properties Boiling point 87 °C/15 mmHg (lit.)

Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Tetrahydro-4-pyranol CAS:2081-44-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inter

Tetrahydro-4-pyranol CAS:2081-44-9

Cas:2081-44-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Tetrahydro-4-pyranol/ LIDE PHARMA- Factory supply / Best price

Cas:2081-44-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:2081-44-9

Cas:2081-44-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:1 Kilogram

FOB Price: $80.0 / 120.0

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Tetrahydro-4-Pyranol

Cas:2081-44-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and qua

Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

oxan-4-ol

Cas:2081-44-9

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products Tetrahydro-2H-pyran-4-ol

Cas:2081-44-9

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Tetrahydro-2H-Pyran-4-Ol

Cas:2081-44-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

Tetrahydro-4-pyranol

Cas:2081-44-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Hangzhou Fandachem Co.,Ltd, a China-based chemical company, specialize in exporting Tetrahydro-4-pyranol,cas:2081-44-9, Please contact us by email freely. We are leading exporter in China. If you really need this cargo, please do not h

Tetrahydro-4-pyranol,cas:2081-44-9 from fandachem

Cas:2081-44-9

Min.Order:1 Metric Ton

Negotiable

Type:Other

inquiry

Synthetic route

Tetrahydro-4H-pyran-4-one
29943-42-8

Tetrahydro-4H-pyran-4-one

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

Conditions
ConditionsYield
Stage #1: Tetrahydro-4H-pyran-4-one With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: With sodium hydroxide In tetrahydrofuran; water
99%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 5℃; for 3h;96%
With C15H18BF3; hydrogen; tert-butylimino-tri(pyrrolidino)phosphorane In tetrahydrofuran at 75℃; under 75007.5 Torr; for 40h; Glovebox;93%
1,3,5-Trioxan
110-88-3

1,3,5-Trioxan

homoalylic alcohol
627-27-0

homoalylic alcohol

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

Conditions
ConditionsYield
Stage #1: 1,3,5-Trioxan; homoalylic alcohol With formic acid at 80℃; for 4h;
Stage #2: With isopropyl alcohol; methanesulfonic acid at 64℃; Product distribution / selectivity;
84%
Stage #1: 1,3,5-Trioxan; homoalylic alcohol With formic acid at 80℃; for 4 - 12.5h;
Stage #2: With ethanol; methanesulfonic acid at 20 - 64℃; Product distribution / selectivity;
81%
Stage #1: 1,3,5-Trioxan; homoalylic alcohol With formic acid at 80℃; for 4h;
Stage #2: With methanol; methanesulfonic acid at 64℃; Product distribution / selectivity;
79%
formaldehyd
50-00-0

formaldehyd

propene
187737-37-7

propene

A

4-methyl-1,3-dioxane
1120-97-4

4-methyl-1,3-dioxane

B

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

C

1.3-butanediol
18826-95-4, 107-88-0

1.3-butanediol

Conditions
ConditionsYield
With cerium(IV) oxide Reagent/catalyst;A 26%
B 11%
C 60%
acetonedicarboxylic acid
542-05-2

acetonedicarboxylic acid

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

Conditions
ConditionsYield
With indium(III) bromide; 1,1,3,3-Tetramethyldisiloxane In toluene at 60℃; for 1h; Inert atmosphere;17%
4-pyrone
108-97-4

4-pyrone

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

Conditions
ConditionsYield
With nickel Hydrogenation;
Multi-step reaction with 2 steps
1: Raney nickel; ethanol / Hydrogenation.bei Raumtemperatur unter Normaldruck
2: Raney nickel / Hydrogenation
View Scheme
formaldehyd
50-00-0

formaldehyd

homoalylic alcohol
627-27-0

homoalylic alcohol

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

Conditions
ConditionsYield
With sulfuric acid; water
formaldehyd
50-00-0

formaldehyd

homoalylic alcohol
627-27-0

homoalylic alcohol

A

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

B

2-[1,3]dioxan-4-yl-ethanol
5684-93-5

2-[1,3]dioxan-4-yl-ethanol

Conditions
ConditionsYield
With sulfuric acid
(1SR,6RS)-3,7-dioxa-bicyclo[4.1.0]heptane
78870-52-7

(1SR,6RS)-3,7-dioxa-bicyclo[4.1.0]heptane

A

Oxan-3-ol
19752-84-2

Oxan-3-ol

B

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In pentane for 4h; Ambient temperature;
pyrone-(4)

pyrone-(4)

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

Conditions
ConditionsYield
With water; platinum Hydrogenation;
4-pyrone
108-97-4

4-pyrone

methanol
67-56-1

methanol

Raney nickel

Raney nickel

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

Conditions
ConditionsYield
at 110℃; under 36775.4 Torr; Hydrogenation;
4-pyrone
108-97-4

4-pyrone

ethanol
64-17-5

ethanol

copper oxide-chromium oxide

copper oxide-chromium oxide

A

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

B

Tetrahydro-4H-pyran-4-one
29943-42-8

Tetrahydro-4H-pyran-4-one

Conditions
ConditionsYield
at 120℃; under 73550.8 - 147102 Torr; Hydrogenation;
tetrahydro-2H-pyran-4-carboxylic acid
5337-03-1

tetrahydro-2H-pyran-4-carboxylic acid

water
7732-18-5

water

A

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

B

octahydro-[4,4']bipyranyl
4677-17-2

octahydro-[4,4']bipyranyl

C

tetrahydro-pyran-4-carboxylic acid tetrahydropyran-4-yl ester

tetrahydro-pyran-4-carboxylic acid tetrahydropyran-4-yl ester

Conditions
ConditionsYield
Anodischen Oxydation des Kalium-Salzes;
formaldehyd
50-00-0

formaldehyd

homoalylic alcohol
627-27-0

homoalylic alcohol

sulfuric acid
7664-93-9

sulfuric acid

A

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

B

2-[1,3]dioxan-4-yl-ethanol
5684-93-5

2-[1,3]dioxan-4-yl-ethanol

formaldehyd
50-00-0

formaldehyd

homoalylic alcohol
627-27-0

homoalylic alcohol

sulfuric acid
7664-93-9

sulfuric acid

water
7732-18-5

water

A

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

B

2-[1,3]dioxan-4-yl-ethanol
5684-93-5

2-[1,3]dioxan-4-yl-ethanol

chelidonic acid
99-32-1

chelidonic acid

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: copper-powder / 350 °C
2: Raney nickel; ethanol / Hydrogenation.bei Raumtemperatur unter Normaldruck
3: Raney nickel / Hydrogenation
View Scheme
2,4,6-trioxo-heptanedioic acid diethyl ester
68854-18-2

2,4,6-trioxo-heptanedioic acid diethyl ester

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: concentrated aqueous hydrochloric acid
2: copper-powder / 350 °C
3: Raney nickel; ethanol / Hydrogenation.bei Raumtemperatur unter Normaldruck
4: Raney nickel / Hydrogenation
View Scheme
TETRAHYDROPYRANE
142-68-7

TETRAHYDROPYRANE

A

2-methyltetrahydrofuran
96-47-9

2-methyltetrahydrofuran

B

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

C

4-butanolide
96-48-0

4-butanolide

D

3,4,5,6-tetrahydro-2H-pyran-2-one
542-28-9

3,4,5,6-tetrahydro-2H-pyran-2-one

E

Tetrahydro-4H-pyran-4-one
29943-42-8

Tetrahydro-4H-pyran-4-one

F

3-chloropropyl formate
1487-44-1

3-chloropropyl formate

Conditions
ConditionsYield
With clorine at 24.84℃; under 800 Torr; Kinetics; Inert atmosphere; Gas phase;
formaldehyd
50-00-0

formaldehyd

propene
187737-37-7

propene

A

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

B

dihydropyran
3174-74-1

dihydropyran

C

homoalylic alcohol
627-27-0

homoalylic alcohol

D

butyraldehyde
123-72-8

butyraldehyde

Conditions
ConditionsYield
With zeolite Zn/H-beta In 1,4-dioxane at 119.84℃; for 2.5h; Catalytic behavior; Reagent/catalyst; Temperature;
formaldehyd
50-00-0

formaldehyd

propene
187737-37-7

propene

A

4-methyl-1,3-dioxane
1120-97-4

4-methyl-1,3-dioxane

B

Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

C

dihydropyran
3174-74-1

dihydropyran

D

homoalylic alcohol
627-27-0

homoalylic alcohol

E

butyraldehyde
123-72-8

butyraldehyde

Conditions
ConditionsYield
With zeolite Zn/H-beta In 1,4-dioxane at 119.84℃; for 2.5h; Catalytic behavior; Reagent/catalyst; Temperature;
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

4-oxanyl methanesulfonate
134419-59-3

4-oxanyl methanesulfonate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 2.5h;100%
With triethylamine In dichloromethane at 0 - 20℃; for 2.5h;100%
With triethylamine In dichloromethane at 0℃; for 1.5h;100%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

6-ethyl-5-hydroxyindan-1-one
760994-01-2

6-ethyl-5-hydroxyindan-1-one

6-ethyl-5-(tetrahydro-2H-pyran-4-yloxy)indan-1-one
760994-03-4

6-ethyl-5-(tetrahydro-2H-pyran-4-yloxy)indan-1-one

Conditions
ConditionsYield
With di-tert-butyl-diazodicarboxylate; PS-triphenylphosphine In tetrahydrofuran100%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

methyl 4-hydroxycinnamate
3943-97-3

methyl 4-hydroxycinnamate

methyl 4-(tetrahydro-4H-pyran-4-yloxy)cinnamate
871109-62-5

methyl 4-(tetrahydro-4H-pyran-4-yloxy)cinnamate

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 25h; Ultrasonification;100%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

1-[3-(5-chloro-thiophen-2-yl)-4-fluoro-phenyl]-ethanone
1100768-37-3

1-[3-(5-chloro-thiophen-2-yl)-4-fluoro-phenyl]-ethanone

1-[3-(5-chloro-thiophen-2-yl)-4-(tetrahydro-pyran-4-yloxy)-phenyl]-ethanone
1100768-38-4

1-[3-(5-chloro-thiophen-2-yl)-4-(tetrahydro-pyran-4-yloxy)-phenyl]-ethanone

Conditions
ConditionsYield
Stage #1: Tetrahydro-pyran-4-ol With sodium hydride In dimethyl sulfoxide at 0 - 10℃; for 0.5h;
Stage #2: 1-[3-(5-chloro-thiophen-2-yl)-4-fluoro-phenyl]-ethanone In dimethyl sulfoxide at 20℃; for 1h;
100%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

(2-hydroxy-5-nitrophenoxy)acetic acid ethyl ester
103095-47-2

(2-hydroxy-5-nitrophenoxy)acetic acid ethyl ester

C15H19NO7
1111236-81-7

C15H19NO7

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 3h; Mitsunobu reaction;100%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

2,6-dinitrobenzonitrile
35213-00-4

2,6-dinitrobenzonitrile

2-nitro-6-(tetrahydro-2H-pyran-4-yloxy)benzonitrile
1093204-86-4

2-nitro-6-(tetrahydro-2H-pyran-4-yloxy)benzonitrile

Conditions
ConditionsYield
100%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

2,6-dichloro-4-(pyrrolidin-1-yl)pyrido[3,4-d]pyrimidine

2,6-dichloro-4-(pyrrolidin-1-yl)pyrido[3,4-d]pyrimidine

6-chloro-4-(pyrrolidin-1-yl)-2-((tetrahydro-2H-pyran-4-yl)oxy)pyrido[3,4-d]pyrimidine

6-chloro-4-(pyrrolidin-1-yl)-2-((tetrahydro-2H-pyran-4-yl)oxy)pyrido[3,4-d]pyrimidine

Conditions
ConditionsYield
Stage #1: Tetrahydro-pyran-4-ol With sodium hydride In tetrahydrofuran at 20℃; for 0.5h;
Stage #2: 2,6-dichloro-4-(pyrrolidin-1-yl)pyrido[3,4-d]pyrimidine In tetrahydrofuran at 20℃; for 2h;
100%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

2-Chloro-3-nitropyridine
5470-18-8

2-Chloro-3-nitropyridine

3-nitro-2-(tetrahydropyran-4-oxy)pyridine
1211758-67-6

3-nitro-2-(tetrahydropyran-4-oxy)pyridine

Conditions
ConditionsYield
Stage #1: Tetrahydro-pyran-4-ol With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 0.5h;
Stage #2: 2-Chloro-3-nitropyridine In tetrahydrofuran; mineral oil at 20℃;
100%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

tetrahydro-2H-pyran-4-yl carbonochloridate
89641-80-5

tetrahydro-2H-pyran-4-yl carbonochloridate

Conditions
ConditionsYield
Stage #1: bis(trichloromethyl) carbonate With pyridine In tetrahydrofuran for 0.166667h; Cooling with ice;
Stage #2: Tetrahydro-pyran-4-ol In tetrahydrofuran at 20℃; for 1h;
99%
With pyridine In dichloromethane at 20℃; for 3h;90%
With pyridine In dichloromethane at 0 - 20℃; for 2h;86%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

ethyl iodoacetate
598-40-3

ethyl iodoacetate

C8H14O3

C8H14O3

Conditions
ConditionsYield
In neat (no solvent) at 20℃; for 0.5h; Green chemistry;99%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

2,2-Dimethylpropanoyl iodide
61915-52-4

2,2-Dimethylpropanoyl iodide

tetrahydro-2H-pyran-4-yl pivalate

tetrahydro-2H-pyran-4-yl pivalate

Conditions
ConditionsYield
In neat (no solvent) at 20℃; for 0.5h; Green chemistry;99%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

2,3-difluorobenzonitrile
21524-39-0

2,3-difluorobenzonitrile

3-fluoro-2-(tetrahydro-2H-pyran-4-yloxy)benzonitrile

3-fluoro-2-(tetrahydro-2H-pyran-4-yloxy)benzonitrile

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; Inert atmosphere;98%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

phosgene
75-44-5

phosgene

tetrahydro-2H-pyran-4-yl carbonochloridate
89641-80-5

tetrahydro-2H-pyran-4-yl carbonochloridate

Conditions
ConditionsYield
In dichloromethane; toluene at 20℃; for 18h;98%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

4-methyl-6-bromo-8-hydroxyquinazoline

4-methyl-6-bromo-8-hydroxyquinazoline

6-bromo-4-methyl-8-((tetrahydro-2H-pyran-4-yl)oxy)quinazoline

6-bromo-4-methyl-8-((tetrahydro-2H-pyran-4-yl)oxy)quinazoline

Conditions
ConditionsYield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; Mitsunobu Displacement; Inert atmosphere;98%
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; Inert atmosphere;98%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

N-(3-(trifluoromethyl)benzyl)-2-(5-fluoro-2-nitrophenyl)isonicotinamide

N-(3-(trifluoromethyl)benzyl)-2-(5-fluoro-2-nitrophenyl)isonicotinamide

N-(3-(trifluoromethyl)benzyl)-2-(2-nitro-5-(tetrahydro-2H-pyran-4-yloxy)phenyl)isonicotinamide

N-(3-(trifluoromethyl)benzyl)-2-(2-nitro-5-(tetrahydro-2H-pyran-4-yloxy)phenyl)isonicotinamide

Conditions
ConditionsYield
Stage #1: Tetrahydro-pyran-4-ol With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.166667h;
Stage #2: N-(3-(trifluoromethyl)benzyl)-2-(5-fluoro-2-nitrophenyl)isonicotinamide In N,N-dimethyl-formamide at 80℃; for 2h;
97%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

2,4,6-trichloropyrido[3,2-d]pyrimidine
1036738-12-1

2,4,6-trichloropyrido[3,2-d]pyrimidine

C12H11Cl2N3O2

C12H11Cl2N3O2

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 20℃; for 16h;97%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

5-bromo-2-hydroxybenzonitrile
40530-18-5

5-bromo-2-hydroxybenzonitrile

5-bromo-2-((tetrahydro-2H-pyran-4-yl)oxy)benzonitrile
876918-62-6

5-bromo-2-((tetrahydro-2H-pyran-4-yl)oxy)benzonitrile

Conditions
ConditionsYield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; for 18h;96%
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; for 18h;96%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

4-hydroxy-3-(trifluoromethyl)benzonitrile
124811-71-8

4-hydroxy-3-(trifluoromethyl)benzonitrile

4-(tetrahydro-2H-pyran-4-yloxy)-3-(trifluoromethyl)benzonitrile
1241910-75-7

4-(tetrahydro-2H-pyran-4-yloxy)-3-(trifluoromethyl)benzonitrile

Conditions
ConditionsYield
With di-tert-butyl-diazodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 20℃;96%
With di-tert-butyl-diazodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 20℃;96%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

isopropyl (S)-2-(tert-butoxy)-2-(4‘-(4,4-dimethylpiperidin-1-yl)-5-hydroxy-6’-methyl-[2,3‘-bipyridin]-5‘-yl)acetate

isopropyl (S)-2-(tert-butoxy)-2-(4‘-(4,4-dimethylpiperidin-1-yl)-5-hydroxy-6’-methyl-[2,3‘-bipyridin]-5‘-yl)acetate

(S)-isopropyl 2-tert-butoxy-2-(4'-(4,4-dimethylpiperidin-1-yl)-6'-methyl-5-(tetrahydro-2H-pyran-4-yloxy)-2,3'-bipyridin-5'-yl)acetate

(S)-isopropyl 2-tert-butoxy-2-(4'-(4,4-dimethylpiperidin-1-yl)-6'-methyl-5-(tetrahydro-2H-pyran-4-yloxy)-2,3'-bipyridin-5'-yl)acetate

Conditions
ConditionsYield
With diisopropyl (E)-azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; Inert atmosphere;96%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

4-bromo-2-chlorophenol
3964-56-5

4-bromo-2-chlorophenol

4-(4-bromo-2-chlorophenoxy)tetrahydropyrane
1056465-06-5

4-(4-bromo-2-chlorophenoxy)tetrahydropyrane

Conditions
ConditionsYield
With di-tert-butyl-diazodicarboxylate In dichloromethane at 0 - 20℃; for 2h;95%
With di-tert-butyl-diazodicarboxylate In dichloromethane at 0 - 20℃; for 2h; Mitsunobu reaction;95%
With di-tert-butyl-diazodicarboxylate In dichloromethane at 0 - 20℃; for 2.08333h; Mitsunobu reaction;95%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

ethyl iodoacetate
598-40-3

ethyl iodoacetate

5-iodopentane-1,3-diyl dipropionate

5-iodopentane-1,3-diyl dipropionate

Conditions
ConditionsYield
In neat (no solvent) at 20℃; for 0.5h; Green chemistry;95%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

2,2-Dimethylpropanoyl iodide
61915-52-4

2,2-Dimethylpropanoyl iodide

5-iodopentane-1,3-diyl dipivalate

5-iodopentane-1,3-diyl dipivalate

Conditions
ConditionsYield
In neat (no solvent) at 20℃; for 0.5h; Green chemistry;95%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

4-chloroquinoline
611-35-8

4-chloroquinoline

4-((tetrahydro-2H-pyran-4-yl)oxy)quinoline

4-((tetrahydro-2H-pyran-4-yl)oxy)quinoline

Conditions
ConditionsYield
Stage #1: Tetrahydro-pyran-4-ol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 0.25h; Inert atmosphere;
Stage #2: 4-chloroquinoline In N,N-dimethyl-formamide; mineral oil at 50℃; for 5h; Inert atmosphere;
95%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

methyl 2-hydroxy-6,7-dihydro-5H-benzocycloheptene-8-carboxylate

methyl 2-hydroxy-6,7-dihydro-5H-benzocycloheptene-8-carboxylate

methyl 2-[(tetrahydropyran-4-yl)oxy]-6,7-dihydro-5H-benzocycloheptene-8-carboxylate

methyl 2-[(tetrahydropyran-4-yl)oxy]-6,7-dihydro-5H-benzocycloheptene-8-carboxylate

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 20℃; for 72h;94%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

3,5-dimethoxy-4-hydroxybenzonitrile
72684-95-8

3,5-dimethoxy-4-hydroxybenzonitrile

3,5-dimethoxy-4-(4-tetrahydropyranyloxy)benzonitrile
1319736-48-5

3,5-dimethoxy-4-(4-tetrahydropyranyloxy)benzonitrile

Conditions
ConditionsYield
With di-tert-butyl-diazodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 20℃;94%
Stage #1: Tetrahydro-pyran-4-ol; 3,5-dimethoxy-4-hydroxybenzonitrile With di-tert-butyl-diazodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 20℃;
Stage #2: With formic acid at 50℃; for 2h;
94%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

C11H24O2Si

C11H24O2Si

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 20℃; for 3h; Inert atmosphere; Schlenk technique;94%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

1-bromo-4-methoxy-benzene
104-92-7

1-bromo-4-methoxy-benzene

4-(4-methoxyphenoxy)-tetrahydro-2H-pyran
1240042-03-8

4-(4-methoxyphenoxy)-tetrahydro-2H-pyran

Conditions
ConditionsYield
With copper(l) iodide; N1, N2-diphenethyloxalamide; sodium t-butanolate In 1,4-dioxane for 24h; Schlenk technique; Inert atmosphere; Molecular sieve; Heating;94%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

toluene-4-sulfonic acid tetrahydropyran-4-yl ester
97986-34-0

toluene-4-sulfonic acid tetrahydropyran-4-yl ester

Conditions
ConditionsYield
Stage #1: Tetrahydro-pyran-4-ol With trimethylamine hydrochloride; triethylamine In dichloromethane at 20℃; for 0.166667h;
Stage #2: p-toluenesulfonyl chloride In dichloromethane at 0 - 20℃; for 17h;
93%
Stage #1: Tetrahydro-pyran-4-ol With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 1h;
Stage #2: p-toluenesulfonyl chloride In tetrahydrofuran; mineral oil at 20℃; for 15h;
92%
With pyridine; dmap In dichloromethane for 168h;90%
Tetrahydro-pyran-4-ol
2081-44-9

Tetrahydro-pyran-4-ol

(4-chlorophenyl)(pyridin-2-yl)methyl 2,2,2-trichloroacetimidate

(4-chlorophenyl)(pyridin-2-yl)methyl 2,2,2-trichloroacetimidate

2-[(4-chlorophenyl)(tetrahydro-2H-pyran-4-yloxy)methyl]pyridine

2-[(4-chlorophenyl)(tetrahydro-2H-pyran-4-yloxy)methyl]pyridine

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In dichloromethane at 20℃; for 24h; Molecular sieve; Inert atmosphere; Cooling with ice;93%

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