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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

Cas:2458-08-4

Min.Order:1

Negotiable

Type:Other

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid

Cas:2458-08-4

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Cholan-24-oic acid,3,7-dihydroxy-12-oxo-, (3a,5b,7a)-

Cas:2458-08-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Cholan-24-oic acid,3,7-dihydroxy-12-oxo-, (3a,5b,7a)-

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China with a history of over ten years, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a ful

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China

Cas:2458-08-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Cholan-24-oic acid,3,7-dihydroxy-12-oxo-, (3a,5b,7a)-

Cas:2458-08-4

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China

Cas:2458-08-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China

Cas:2458-08-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China

Cas:2458-08-4

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China

Cas:2458-08-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Cholan-24-oic acid,3,7-dihydroxy-12-oxo-, (3a,5b,7a)-

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Our own factory produces direct sales with absolute price advantage Application:Pharmaceutical industry Transportation:By sea Port:Shanghai/tianjin

Cholan-24-oic acid,3,7-dihydroxy-12-oxo-, (3a,5b,7a)-

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China Application:SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Other

inquiry

NANJING SUNNY PHARMATECH CO., LTD

We are professional supplier in China for this product, we are dedicated to providing customers with the best quality, price, and service. Please feel free to send us inquiries.Appearance:Please contact us for product details Package:As per shipment

3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta

3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any por

12-DEHYDROCHOLIC ACID

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

2458-08-4

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China Application:intermediate Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to airport) or by sea LCL/FCL for large amount.

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Click Biotechnology Co.,Ltd

1. Quality is the best and packaging is good. Each batch of products must pass our quality control before being approved for sale. 2. Strict selection of raw materials, our products have the highest purity. 3. Fast delivery. We have the stock t

3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid

Cas:2458-08-4

Min.Order:25 Milligram

Negotiable

Type:Trading Company

inquiry

Hubei Jusheng Technology Co., Ltd.,

1,Best Quality: Our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other countries, and we have got very good feedback from our customers.so

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China

Cas:2458-08-4

Min.Order:10 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Taizhou volsen chemical Co., Ltd

We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Minshang Biotechnology Co., Ltd

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China Application:intermediate

2458-08-4

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fenjun Chemical Co Ltd.

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China Application:SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China

SAGECHEM/ 12-Ketochenodeoxycholic acid /Manufacturer in China

Cas:2458-08-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

sodium cholate
361-09-1

sodium cholate

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

Conditions
ConditionsYield
With ethylenediaminetetraacetic acid; Acinetobacter calcoaceticus lwoffii 12α-hydroxysteroid dehydrogenase; sodium pyruvate; NAD; 2-hydroxyethanethiol; lactate dehydrogenase In aq. phosphate buffer at 22℃; pH=8.5; Enzymatic reaction;98%
cholic acid
81-25-4

cholic acid

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

Conditions
ConditionsYield
With NAD(P)H oxidase; nicotinamide adenine dinucleotide-dependent HSDH from Eggerthella lenta; NAD; oxygen In methanol; aq. phosphate buffer at 21℃; for 24h; pH=8; Catalytic behavior; Kinetics; Reagent/catalyst; Concentration; pH-value; Temperature; Flow reactor; Enzymatic reaction;92%
With ammonium acetate; potassium phosphate; sodium azide; diothiothreitol for 48h; Ambient temperature; NADP, α-ketoglutarate, 12α-hydroxysteroid dehydrogenase, glutamate dehydrogenase; pH 8;85%
With sodium pyruvate; NAD In aq. phosphate buffer at 30℃; for 1h; pH=8; Kinetics; Enzymatic reaction;85%
3α,7α-dihydroxy-12-oxo-5β-cholan-24-amide
176108-12-6

3α,7α-dihydroxy-12-oxo-5β-cholan-24-amide

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol for 8h; Heating;90%
methyl 3α,7α-diacetoxy-12-hydroxycholanate

methyl 3α,7α-diacetoxy-12-hydroxycholanate

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

Conditions
ConditionsYield
Stage #1: methyl 3α,7α-diacetoxy-12-hydroxycholanate With jones' reagent In acetone at 20℃; for 0.166667h;
Stage #2: With sodium hydroxide In 1,4-dioxane for 6h; Heating; Further stages.;
87%
3,7-diketocholic acid sodium salt

3,7-diketocholic acid sodium salt

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

Conditions
ConditionsYield
With phosphate buffer; 3α-HSDH from Pseudomonas paucimobilis; NAD; iso-butanol In water at 22℃; for 48h;80%
methyl 3α,7α-diacetoxy-12-one-5β-cholest-24-carboxylate
28535-81-1

methyl 3α,7α-diacetoxy-12-one-5β-cholest-24-carboxylate

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

Conditions
ConditionsYield
With water; sodium hydroxide In methanol at 25 - 40℃; for 5h;62.7%
With potassium hydroxide
With sodium hydroxide
Alkaline conditions;
dehydrocholic acid
81-23-2

dehydrocholic acid

A

7α,12α-dihydroxy-3-oxocholanoic acid
2304-89-4

7α,12α-dihydroxy-3-oxocholanoic acid

B

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

C

7-ketodeoxycholic acid
911-40-0

7-ketodeoxycholic acid

Conditions
ConditionsYield
With sodium tetrahydroborate; sodium hydrogencarbonate at 0℃; for 24h;A 4 % Chromat.
B 62%
C 8 % Chromat.
cholic acid
81-25-4

cholic acid

A

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

B

7-ketodeoxycholic acid
911-40-0

7-ketodeoxycholic acid

C

7,12-dioxolitocholic acid
517-33-9

7,12-dioxolitocholic acid

D

dehydrocholic acid
81-23-2

dehydrocholic acid

Conditions
ConditionsYield
With sodium hydroxide; sodium perchlorate; sodium chloride In water at 25℃; for 6h; pH=12; Product distribution; Further Variations:; electricity; Electrochemical reaction; 200 mA;A 10%
B 33%
C 46%
D 11%
dehydrocholic acid
81-23-2

dehydrocholic acid

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

Conditions
ConditionsYield
With acetic acid; platinum Hydrogenation;
dehydrocholic acid
81-23-2

dehydrocholic acid

acetic acid
64-19-7

acetic acid

platinum

platinum

hydrogen (2 mol)

hydrogen (2 mol)

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

Conditions
ConditionsYield
Hydrogenation;
(3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-amide
6786-09-0

(3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-amide

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 78 percent / Br2, Na2CO3 / methanol / 72 h / 0 - 4 °C
2: 90 percent / KOH / methanol / 8 h / Heating
View Scheme
methyl cholate
1448-36-8

methyl cholate

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 86 percent / aq. NH3 / methanol / 120 h / 100 °C
2: 78 percent / Br2, Na2CO3 / methanol / 72 h / 0 - 4 °C
3: 90 percent / KOH / methanol / 8 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: benzene
2: chromium (VI)-oxide; acetic acid
3: methanol. KOH-solution
View Scheme
Multi-step reaction with 3 steps
1: dmap; triethylamine / dichloromethane / 3 h / 20 °C
2: acetic acid; sodium hypochlorite / ethyl acetate / 5 h / 20 °C
3: sodium hydroxide; water / methanol / 5 h / 25 - 40 °C
View Scheme
Multi-step reaction with 3 steps
1: pyridine
2: chromium(VI) oxide
3: Alkaline conditions
View Scheme
methyl 3α,7α-diacetoxy-12α-hydroxy cholanate
3749-87-9

methyl 3α,7α-diacetoxy-12α-hydroxy cholanate

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: chromium (VI)-oxide; acetic acid
2: methanol. KOH-solution
View Scheme
Multi-step reaction with 2 steps
1: acetic acid; sodium hypochlorite / ethyl acetate / 5 h / 20 °C
2: sodium hydroxide; water / methanol / 5 h / 25 - 40 °C
View Scheme
Multi-step reaction with 2 steps
1: chromium(VI) oxide
2: Alkaline conditions
View Scheme
Lithocholic acid
434-13-9

Lithocholic acid

A

cholic acid
81-25-4

cholic acid

B

ursodeoxycholic acid
128-13-2

ursodeoxycholic acid

C

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

D

ursocholic acid
2955-27-3

ursocholic acid

Conditions
ConditionsYield
With Amycolatopsis lurida VKM Ac-1242 In methanol; aq. phosphate buffer pH=7; Microbiological reaction;
cholic acid
81-25-4

cholic acid

A

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

B

7-ketodeoxycholic acid
911-40-0

7-ketodeoxycholic acid

Conditions
ConditionsYield
With Rhodococcus (Nocardiaceae) sp. E-14C strains culture broth; air In methanol; water at 29℃; pH=7; Reagent/catalyst; Microbiological reaction;
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

C48H76N2O8

C48H76N2O8

Conditions
ConditionsYield
With hydrazine hydrate In acetic acid at 20℃; for 24h;96%
formic acid
64-18-6

formic acid

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

3α,7α-diformyloxy-12-oxo-5β-cholanoic acid

3α,7α-diformyloxy-12-oxo-5β-cholanoic acid

Conditions
ConditionsYield
Stage #1: formic acid; 3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid With perchloric acid at 50 - 55℃; for 1h;
Stage #2: With acetic anhydride at 20℃;
96%
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With potassium hydroxide; hydrazine In 2-methoxy-ethanol; water at 110 - 135℃; for 12h; Wolff-Kishner reduction;90%
With potassium hydroxide; ethylene glycol weiteres Reagens: N2H4;
With potassium hydroxide; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol weiteres Reagens: N2H4;
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

A

7,12-dioxolitocholic acid
517-33-9

7,12-dioxolitocholic acid

B

3α,7β-dihydroxy-12-oxo-5β-cholane-24-oic acid
81873-91-8

3α,7β-dihydroxy-12-oxo-5β-cholane-24-oic acid

Conditions
ConditionsYield
With air; Xanthomonas maltophilia In water at 30℃; for 96h; pH=8;A 85%
B 10%
With Xanthomonas maltophilia In water at 30℃; for 96h; pH=8; anaerobic;A 10%
B 80%
methanol
67-56-1

methanol

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

methyl 3α,7α-dihydroxy-12-oxo-5β-cholan-24-oate
10538-64-4

methyl 3α,7α-dihydroxy-12-oxo-5β-cholan-24-oate

Conditions
ConditionsYield
With sulfuric acid at 60℃; for 5h;82.1%
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

toluene-4-sulfonic acid hydrazide
1576-35-8

toluene-4-sulfonic acid hydrazide

3α,7α-dihydroxy-12-oxocholanic acid tosylhydrazone
79580-95-3

3α,7α-dihydroxy-12-oxocholanic acid tosylhydrazone

Conditions
ConditionsYield
In acetic acid for 12h; Ambient temperature;70%
7-Ketolithocholic acid
4651-67-6

7-Ketolithocholic acid

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

C48H76N2O7

C48H76N2O7

Conditions
ConditionsYield
With hydrazine hydrate In acetic acid at 20℃; for 24h;45%
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

7-ketodeoxycholic acid
911-40-0

7-ketodeoxycholic acid

C48H76N2O8

C48H76N2O8

Conditions
ConditionsYield
With hydrazine hydrate In acetic acid at 20℃; for 24h;38%
12-oxolithocholic acid
5130-29-0

12-oxolithocholic acid

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

C48H76N2O7

C48H76N2O7

Conditions
ConditionsYield
With hydrazine hydrate In acetic acid at 20℃; for 24h;37%
methyl magnesium iodide
917-64-6

methyl magnesium iodide

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

3α,7α,12α-trihydroxy-12β-methyl-5β-cholanic acid

3α,7α,12α-trihydroxy-12β-methyl-5β-cholanic acid

Conditions
ConditionsYield
In tetrahydrofuran; diethyl ether at -20℃; for 1.5h; Grignard Reaction;27%
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

methyl 3α,7α-dihydroxy-12-oxo-5β-cholan-24-oate
10538-64-4

methyl 3α,7α-dihydroxy-12-oxo-5β-cholan-24-oate

ethanol
64-17-5

ethanol

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

3α.7α-dihydroxy-12-oxo-5β-cholanoic acid-(24)-ethyl ester

3α.7α-dihydroxy-12-oxo-5β-cholanoic acid-(24)-ethyl ester

Conditions
ConditionsYield
With sulfuric acid
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

methylcholanthrene
56-49-5

methylcholanthrene

Conditions
ConditionsYield
at 320 - 340℃; Behandlung des Reaktionsprodukts mit Selen bei 320-340grad;
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

7,12-dioxolitocholic acid
517-33-9

7,12-dioxolitocholic acid

Conditions
ConditionsYield
With bromine
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

O-carboxymethylhydroxylamine hydrochloride
20295-82-3

O-carboxymethylhydroxylamine hydrochloride

12E-[O-(carboxymethyl)oxiimino]-3α,7α-dihydroxy-5β-cholan-24-oic acid

12E-[O-(carboxymethyl)oxiimino]-3α,7α-dihydroxy-5β-cholan-24-oic acid

Conditions
ConditionsYield
With pyridine at 90℃; for 4h;
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

C56H67N5O8

C56H67N5O8

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: pyridine / 4 h / 90 °C
2.1: Et3N / methanol / 1 h / 20 °C
2.2: methanol / 0.5 h / 20 °C
2.3: 51 percent / 20 °C
View Scheme
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

ursodeoxycholic acid
128-13-2

ursodeoxycholic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 70 percent / acetic acid / 12 h / Ambient temperature
2: NaBH4 / acetic acid / 3 h / Ambient temperature
3: HCl
4: pyridine / benzene
5: pyridine / Ambient temperature
6: KO2/18-crown-6 ether / dimethylsulfoxide / 3 h
View Scheme
Multi-step reaction with 3 steps
2: nicotinamide adenine dinucleotide phosphate; 7α-hydroxysteroid dehydrogenase / Enzymatic reaction
3: NADPH; 7β-hydroxysteroid dehydrogenases from Clostridium absonum and Collinsella aerofaciens / Enzymatic reaction
View Scheme
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

chenodeoxycholic acid methyl ester
3057-04-3

chenodeoxycholic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 70 percent / acetic acid / 12 h / Ambient temperature
2: NaBH4 / acetic acid / 3 h / Ambient temperature
3: HCl
View Scheme

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