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Antimex Chemical Limied

ProName: cholic acid Cas : 81-25-4 Molecular Formula: C24H40O5 Appearance: White crystalline powder Application: the cholesterol is still the raw mate... cholic acid CAS 81-25-4 DeliveryTime: according to the contract PackAge: Packaging acco

Cholic acid CAS 81-25-4

Cas:81-25-4

Min.Order:1 Metric Ton

FOB Price: $6.5

Type:Lab/Research institutions

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Xi'an Quanao Biotech Co., Ltd.

Xi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi

Ox bile extract powder 40% Cholic acid Cas:81-25-4

Cas:81-25-4

Min.Order:1 Kilogram

FOB Price: $60.0 / 79.0

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Cholic acid Manufacturer/High quality/Best price/In stock

Cas:81-25-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Analysis tests Standard Results Appearance White or off-white powder White powder Identification

High purity Various Specifications Cholic acid CAS:81-25-4

Cas:81-25-4

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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Hubei Vanz Pharm Co.,Ltd

Hubei Vanz Pharm Co., Ltd, which the manufacture of APIs, supplements raw powder and some customization products. is located in Wuhan, Hubei province. We are one of the most professional company in pharm/chmecial industry for more than 10 years. W

Cholic acid CAS 81-25-4

Cas:81-25-4

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Cholic Acid (Ca) supplier in China

Cas:81-25-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Kono Chem Co.,Ltd

Specifications CAS No.: 81-25-4 Other Names: cholic acid MF: C24H40O5 EINECS No.: 81-25-4 Place of Origin: Shaanxi, China (Mainland)

Cholic acid 99% powder

Cas:81-25-4

Min.Order:1 Kilogram

Negotiable

Type:Other

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White Crystalline Powder Storage:Store at RT. Package:1kg

Manufacturer supply Cholic acid CAS 81-25-4 with competitive price

Cas:81-25-4

Min.Order:5 Kilogram

FOB Price: $500.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Cholic acid

Cas:81-25-4

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Cholic acid 81-25-4 GMP Manufacturer

Cas:81-25-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Xi`an Eastling Biotech Co., Ltd.

We have strong ability to finish your private labels. Most retailers have their own brand, they need customized supplements and packaging services. If you are seeking to a trusted manufacturer, we can promise you that adding your company name, creati

High Quality Bile acid Cholic acid CAS 81-25-4

Cas:81-25-4

Min.Order:1 Gram

FOB Price: $26.0

Type:Trading Company

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Shanxi Zorui Biotechnology Co.Ltd.

Zorui combines R&D, production and sales into its operations, While continuously providing high-quality raw materials, we also provide and optimize technical solutions for customers to achieve mutual benefit. We adhere to the "quality, integ

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Cholic acid

Cas:81-25-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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GIHI CHEMICALS CO.,LIMITED

GIHI CHEMICALS exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, GIHI CHEMICALS is your best choice. pls contact with us freely for getting detailed prod

Cholic acid

Cas:81-25-4

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

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Leader Biochemical Group

About Product Specifications Testing Item Specifications Results Appearance White or white crystalline powder Complies

China Largest Factory Manufacturer Supply ≥98% Cholic Acid CAS 81-25-4

Cas:81-25-4

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Cholic acid Basic information Product Name: Cholic acid Synonyms: 3,7,12-Trihydroxy-cholan-24-oic acid;5beta-Cholan-24-oic acid, 3alpha,7alpha,12alpha-trihydroxy-;Cholan-

TIANFU-CHEM CAS:81-25-4 Cholic acid

Cas:81-25-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

Cholic acid 81-25-4

Cas:81-25-4

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 81-25-4 with competitive price

Cas:81-25-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Factory Supply High Quality CAS 81-25-4 cholic acid

Cas:81-25-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua

Cholic Acid Research Chemicals CAS: 81-25-4 white powder

Cas:81-25-4

Min.Order:10 Gram

Negotiable

Type:Other

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Hefei TNJ chemical industry co.,ltd

1. We are one of the domestic largest manufacturers of API; 2. We are always supplier of products with higher quality and at more competitive price; 3. We are supplier of safe and ecofriendly products ; 4. We provide stable supply and effi

Manufacturer of Cholic acid at Factory Price

Cas:81-25-4

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Cholan-24-oicacid, 3,7,12-trihydroxy-, (3α,5β,7α,12α)- 81-25-4

Cas:81-25-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Cholic acid Gallbladder medicine

Cas:81-25-4

Min.Order:1 Kilogram

FOB Price: $60.0 / 90.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Cholic acid CAS:81-25-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, s

Cholic acid CAS:81-25-4

Cas:81-25-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Cholan-24-oicacid, 3,7,12-trihydroxy-, (3α,5β,7α,12α)-

Cas:81-25-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products with competi

Factory price Cholic acid cas no. 81-25-4 with high purity

Cas:81-25-4

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

Ursodeoxycholic acid CAS 81-25-4

Cas:81-25-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:81-25-4

Cas:81-25-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Lonwin Chemical Group Limited

Cholic acid CAS: 81-25-4 Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard Shelf life 2 years Storage should be stored in a well-closed cont

Factory supply Cholic acid

Cas:81-25-4

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

inquiry

ShangHai Soyoung Biotechnology Inc

Shanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many ye

Bile Bovine powder

Cas:81-25-4

Min.Order:25 Kilogram

FOB Price: $78.0

Type:Lab/Research institutions

inquiry

Synthetic route

3-ketocholic acid, sodium salt

3-ketocholic acid, sodium salt

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With phosphate buffer; 3α-HSDH from Pseudomonas paucimobilis; NAD; iso-butanol In water at 22℃; for 48h;100%
methyl cholate
1448-36-8

methyl cholate

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol; water for 0.0666667h; microwave irradiation;99%
10-undecenyl 7α,12α,3α-trihydroxy-5β-cholan-24-oate
850210-60-5

10-undecenyl 7α,12α,3α-trihydroxy-5β-cholan-24-oate

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol; water for 0.1h; microwave irradiation;98%
octanyl cholate
211448-18-9

octanyl cholate

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol; water for 0.0833333h; microwave irradiation;98%
ethyl (3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-oate
15073-99-1, 47676-48-2, 101230-69-7, 101230-70-0

ethyl (3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-oate

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol; water for 0.0666667h; microwave irradiation;97%
With sodium hydroxide In ethanol at 30℃; for 1h;15 mg
benzyl 3α,7α,12α-trihydroxyl-5β-cholestane-24-carboxylic ester
105730-97-0

benzyl 3α,7α,12α-trihydroxyl-5β-cholestane-24-carboxylic ester

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol; water for 0.0666667h; microwave irradiation;96%
(3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-oic acid 1,1-dimethylethyl ester
122752-67-4

(3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-oic acid 1,1-dimethylethyl ester

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol; water for 0.0666667h; microwave irradiation;95%
sodium N-nitrosotaurocholate
76757-84-1

sodium N-nitrosotaurocholate

A

2-hydroxyethanesulfonic acid
107-36-8

2-hydroxyethanesulfonic acid

B

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With water at 37℃; Rate constant; Mechanism; pH 7.0 - 9.0;A 61%
B 94%
octacos-10-enyl 7α,12α,3α-trihydroxy-5β-cholan-24-oate
850210-62-7

octacos-10-enyl 7α,12α,3α-trihydroxy-5β-cholan-24-oate

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol; water for 0.133333h; microwave irradiation;94%
N-nitrosoglycocholic acid
76757-85-2

N-nitrosoglycocholic acid

A

glycolic Acid
79-14-1

glycolic Acid

B

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With water at 37℃; Rate constant; Mechanism; pH 7.0 - 9.0;A 85%
B 50%
7-ketodeoxycholic acid
911-40-0

7-ketodeoxycholic acid

A

cholic acid
81-25-4

cholic acid

B

ursocholic acid
2955-27-3

ursocholic acid

Conditions
ConditionsYield
With sodium In propan-1-ol for 3h; Reflux;A 10%
B 80%
dehydrocholic acid
81-23-2

dehydrocholic acid

A

cholic acid
81-25-4

cholic acid

B

7α,12α-dihydroxy-3-oxocholanoic acid
2304-89-4

7α,12α-dihydroxy-3-oxocholanoic acid

C

7α,12β-dihydroxy-3-keto-5β-cholan-24-oic acid
153222-72-1

7α,12β-dihydroxy-3-keto-5β-cholan-24-oic acid

Conditions
ConditionsYield
With sodium tetrahydroborate In ethanol at 20℃; for 10h; Product distribution; Further Variations:; Reagents; Solvents;A 42%
B 23%
C 15%
dehydrocholic acid
81-23-2

dehydrocholic acid

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With lithium tri-t-butoxyaluminum hydride In tetrahydrofuran at 20 - 40℃; for 17h;29.6%
5β.24ξH-ergostanepentol-(3α.7α.12α.24.25)

5β.24ξH-ergostanepentol-(3α.7α.12α.24.25)

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
Umwandlung im Organismus des Meerschweinchens;
Multi-step reaction with 2 steps
1: pyridine / Erwaermen auf dem Dampfbad
2: CrO3; acetic acid / und Erwaermen des Reaktionsprodukts mit aethanol.KOH
View Scheme
(25R)-3α,7α,12α,26-tetraacetoxy-26,26-dimethyl-5β-cholestane

(25R)-3α,7α,12α,26-tetraacetoxy-26,26-dimethyl-5β-cholestane

cholic acid
81-25-4

cholic acid

cholic acid-anhydride

cholic acid-anhydride

sodium ethanolate
141-52-6

sodium ethanolate

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
at 130℃;
7-ketodeoxycholic acid
911-40-0

7-ketodeoxycholic acid

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With cultures of aspergillus cinnamomeus
With cultures of gliocladium spec
Trihydroxycholestanoic acid
547-98-8

Trihydroxycholestanoic acid

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With Tris-HCl buffer; coenzyme-A; rat liver homogenate; ATP; magnesium chloride; nicotinamide adenine dinucleotide In methanol at 37℃; for 1h; incubation aerobically; pH= 8.5;
(24S,25S)-3α,7α,12α,24-tetrahydroxy-5β-cholestan-26-oic acid
85552-44-9

(24S,25S)-3α,7α,12α,24-tetrahydroxy-5β-cholestan-26-oic acid

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With Tris-HCl buffer; coenzyme-A; rat liver homogenate; ATP; magnesium chloride; nicotinamide adenine dinucleotide In methanol at 37℃; for 1h; incubation aerobically; pH= 8.5;
(24S,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestan-26-oic acid
85552-43-8

(24S,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestan-26-oic acid

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With Tris-HCl buffer; coenzyme-A; rat liver homogenate; ATP; magnesium chloride; nicotinamide adenine dinucleotide In methanol at 37℃; for 1h; incubation aerobically; pH= 8.5;
(24R,25S)-3α,7α,12α,24-tetrahydroxy-5β-cholestan-26-oic acid
85552-42-7

(24R,25S)-3α,7α,12α,24-tetrahydroxy-5β-cholestan-26-oic acid

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With Tris-HCl buffer; coenzyme-A; rat liver homogenate; ATP; magnesium chloride; nicotinamide adenine dinucleotide In methanol at 37℃; for 1h; incubation aerobically; pH= 8.5;
(24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestan-26-oic acid
85552-41-6

(24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestan-26-oic acid

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With Tris-HCl buffer; coenzyme-A; rat liver homogenate; ATP; magnesium chloride; nicotinamide adenine dinucleotide In methanol at 37℃; for 1h; incubation aerobically; pH= 8.5;
7,12-dihydroxy-3-(sulfooxy)(3α,5β,7α,12α)-cholan-24-oic acid

7,12-dihydroxy-3-(sulfooxy)(3α,5β,7α,12α)-cholan-24-oic acid

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
With hydrogenchloride In methanol; acetone at 37℃; Kinetics; var. temp., solvent;
cholic acid acetonitrile

cholic acid acetonitrile

A

cholic acid
81-25-4

cholic acid

B

acetonitrile
75-05-8

acetonitrile

Conditions
ConditionsYield
at 85℃; Rate constant; Kinetics; Mechanism; Heating; energy data; Ea; var. temp.;
6A,6C-bis(2-naphthylsulfonyl)-γ-cyclodextrin cholic acid 1:1 complex

6A,6C-bis(2-naphthylsulfonyl)-γ-cyclodextrin cholic acid 1:1 complex

A

cholic acid
81-25-4

cholic acid

B

6A,6C-bis(2-naphthylsulfonyl)-γ-cyclodextrin

6A,6C-bis(2-naphthylsulfonyl)-γ-cyclodextrin

Conditions
ConditionsYield
In water; ethylene glycol at 25℃; Equilibrium constant; decomplexation;
6A,6D-bis(2-naphthylsulfonyl)-γ-cyclodextrin cholic acid 1:1 complex

6A,6D-bis(2-naphthylsulfonyl)-γ-cyclodextrin cholic acid 1:1 complex

A

cholic acid
81-25-4

cholic acid

B

6A,6D-bis(2-naphthylsulfonyl)-γ-cyclodextrin

6A,6D-bis(2-naphthylsulfonyl)-γ-cyclodextrin

Conditions
ConditionsYield
In water; ethylene glycol at 25℃; Equilibrium constant; decomplexation;
6A,6E-bis(2-naphthylsulfonyl)-γ-cyclodextrin cholic acid 1:1 complex

6A,6E-bis(2-naphthylsulfonyl)-γ-cyclodextrin cholic acid 1:1 complex

A

cholic acid
81-25-4

cholic acid

B

6A,6E-bis(2-naphthylsulfonyl)-γ-cyclodextrin

6A,6E-bis(2-naphthylsulfonyl)-γ-cyclodextrin

Conditions
ConditionsYield
In water; ethylene glycol at 25℃; Equilibrium constant; decomplexation;
dehydrocholic acid
81-23-2

dehydrocholic acid

acetic acid
64-19-7

acetic acid

platinum

platinum

hydrogen (3 mol)

hydrogen (3 mol)

cholic acid
81-25-4

cholic acid

Conditions
ConditionsYield
Hydrogenation;
3α.7α.12α-triacetoxy-5β.24ξH-ergostanediol-(24.25)

3α.7α.12α-triacetoxy-5β.24ξH-ergostanediol-(24.25)

pentahydroxybufostan

pentahydroxybufostan

A

cholic acid
81-25-4

cholic acid

B

3α.7α.12α-trihydroxy-25-methyl-5β-cholestanone-(24)

3α.7α.12α-trihydroxy-25-methyl-5β-cholestanone-(24)

Conditions
ConditionsYield
With chromium(VI) oxide; acetic acid und Erwaermen des Reaktionsprodukts mit aethanol.KOH;
methanol
67-56-1

methanol

cholic acid
81-25-4

cholic acid

methyl cholate
1448-36-8

methyl cholate

Conditions
ConditionsYield
With diazomethyl-trimethyl-silane In methanol; toluene at 20℃; for 2h;100%
With acetyl chloride at 20℃; for 72h;100%
With acetyl chloride at 20℃; for 0.75h;100%
cholic acid
81-25-4

cholic acid

dehydrocholic acid
81-23-2

dehydrocholic acid

Conditions
ConditionsYield
With sodium hydroxide; sodium perchlorate; sodium chloride In water at 25℃; for 40h; pH=12; Electrochemical reaction; 50 mA;100%
With sodium bromate; ammonium cerium (IV) nitrate In water; acetonitrile at 80℃; for 3h; Temperature; Green chemistry;95%
With sodium bromate; ammonium cerium (IV) nitrate In water; acetonitrile at 80℃; for 3.3h;95%
cholic acid
81-25-4

cholic acid

dimethyl amine
124-40-3

dimethyl amine

(R)-N,N-dimethyl-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-17-yl)valeramide
86678-85-5

(R)-N,N-dimethyl-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-17-yl)valeramide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere;100%
With tributyl-amine; chloroformic acid ethyl ester In 1,4-dioxane 10 deg C, 30 min then rt., 2 h;78%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 10h;74.2%
With water at 250℃;
With tributyl-amine; chloroformic acid ethyl ester Multistep reaction;
cholic acid
81-25-4

cholic acid

ethylenediamine
107-15-3

ethylenediamine

N-(2-aminoethyl)(3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-amide
78793-09-6

N-(2-aminoethyl)(3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-amide

Conditions
ConditionsYield
Stage #1: cholic acid With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide In dimethyl sulfoxide at 20℃; for 20h;
Stage #2: ethylenediamine In dimethyl sulfoxide at 20℃; for 24h;
100%
With tributyl-amine; isobutyl chloroformate 1) dioxane, 10 deg C, 2) H2O, 10 deg C, 1 h; Yield given. Multistep reaction;
1-hydroxy-pyrrolidine-2,5-dione
6066-82-6

1-hydroxy-pyrrolidine-2,5-dione

cholic acid
81-25-4

cholic acid

cholic acid N-succinimidyl ester
70090-26-5

cholic acid N-succinimidyl ester

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In tetrahydrofuran; acetonitrile at 20℃; for 24h; Inert atmosphere;100%
With dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃; for 24h; Inert atmosphere;100%
With dicyclohexyl-carbodiimide In tetrahydrofuran; acetonitrile at 25℃; for 18h;97%
cholic acid
81-25-4

cholic acid

A

methyl chelate

methyl chelate

B

methyl cholate
1448-36-8

methyl cholate

Conditions
ConditionsYield
In tetrahydrofuranA 100%
B n/a
cholic acid
81-25-4

cholic acid

diazomethyl-trimethyl-silane
18107-18-1

diazomethyl-trimethyl-silane

methyl cholate
1448-36-8

methyl cholate

Conditions
ConditionsYield
In methanol; hexane; toluene at 20℃;100%
N-Methyltaurine
107-68-6

N-Methyltaurine

cholic acid
81-25-4

cholic acid

3α,7α,12α-trihydroxy-5β-cholan-24-oyl-N-methyltaurine
93790-72-8

3α,7α,12α-trihydroxy-5β-cholan-24-oyl-N-methyltaurine

Conditions
ConditionsYield
With triethylamine; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride In N,N-dimethyl-formamide at 20℃; for 1h;100%
ethanol
64-17-5

ethanol

cholic acid
81-25-4

cholic acid

ethyl (3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-oate
15073-99-1, 47676-48-2, 101230-69-7, 101230-70-0

ethyl (3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-oate

Conditions
ConditionsYield
With sulfuric acid for 10h;99%
With toluene-4-sulfonic acid; sodium sulfate for 0.05h; microwave irradiation;95%
With lipase from the fungus rhizomucor miehei In di-isopropyl ether at 40℃; for 48h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Enzymatic reaction;85%
cholic acid
81-25-4

cholic acid

diazodiphenylmethane
908093-98-1

diazodiphenylmethane

diphenylmethyl cholate
459869-01-3

diphenylmethyl cholate

Conditions
ConditionsYield
In methanol; chloroform at 45℃; for 18h;99%
cholic acid
81-25-4

cholic acid

acetyl chloride
75-36-5

acetyl chloride

cholic acid 3,7,12-triacetate
52840-09-2

cholic acid 3,7,12-triacetate

Conditions
ConditionsYield
at 20℃; for 17h;99%
for 12h; Heating;79%
at 20℃; for 17h;
succinic acid anhydride
108-30-5

succinic acid anhydride

cholic acid
81-25-4

cholic acid

3α-(succinoyloxy)-7α,12α-dihydroxy-5β-cholan-24-oic acid

3α-(succinoyloxy)-7α,12α-dihydroxy-5β-cholan-24-oic acid

Conditions
ConditionsYield
In pyridine at 20 - 25℃; for 7h;99%
With pyridine at 80℃; for 14h;99%
With triethylamine for 24h; Reflux;80%
With pyridine at 80℃; for 43h;
cholic acid
81-25-4

cholic acid

methyl iodide
74-88-4

methyl iodide

(R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trimethoxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]-phenanthren-17-yl]pentanoic acid
117832-92-5

(R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trimethoxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]-phenanthren-17-yl]pentanoic acid

Conditions
ConditionsYield
Stage #1: cholic acid With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 1h;
Stage #2: methyl iodide In tetrahydrofuran; mineral oil at 0 - 41℃; for 60h;
99%
Stage #1: cholic acid With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h; Inert atmosphere;
Stage #2: methyl iodide In tetrahydrofuran; mineral oil at 20℃; for 72h; Inert atmosphere;
82%
Stage #1: cholic acid With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.166667h;
Stage #2: methyl iodide In tetrahydrofuran; mineral oil at 0 - 20℃; for 36h;
64%
Stage #1: cholic acid With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: methyl iodide In tetrahydrofuran; mineral oil at 20℃; for 18h; Inert atmosphere;
62%
cholic acid
81-25-4

cholic acid

acetyl chloride
75-36-5

acetyl chloride

methyl cholate
1448-36-8

methyl cholate

Conditions
ConditionsYield
In methanol for 12.5h; Cooling with ice;99%
In methanol
cholic acid
81-25-4

cholic acid

3α,7α,12α-trihydroxycholan-24-ol
3758-71-2

3α,7α,12α-trihydroxycholan-24-ol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 20℃;98%
With lithium aluminium tetrahydride In tetrahydrofuran Reflux;92%
With lithium aluminium tetrahydride In tetrahydrofuran Heating;88%
cholic acid
81-25-4

cholic acid

acetic anhydride
108-24-7

acetic anhydride

cholic acid 3,7,12-triacetate
52840-09-2

cholic acid 3,7,12-triacetate

Conditions
ConditionsYield
With pyridine; dmap at 50℃; for 2h;98%
With pyridine; dmap at 20℃; for 3.5h;95.5%
With dmap In pyridine for 3.5h; 0 deg C then rt., 3.5 h;94.7%
formic acid
64-18-6

formic acid

cholic acid
81-25-4

cholic acid

3α-O-formylcholic acid

3α-O-formylcholic acid

Conditions
ConditionsYield
at 60℃; for 4h;98%
1,8-diaminooctan
373-44-4

1,8-diaminooctan

cholic acid
81-25-4

cholic acid

N1-cholyl-1,8-octanediamine

N1-cholyl-1,8-octanediamine

Conditions
ConditionsYield
Stage #1: cholic acid With O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In chloroform; N,N-dimethyl-formamide at 20℃; for 0.333333h;
Stage #2: 1,8-diaminooctan In chloroform; N,N-dimethyl-formamide at 20℃; for 4h;
98%
formic acid
64-18-6

formic acid

cholic acid
81-25-4

cholic acid

cholic acid triformate
2097-89-4

cholic acid triformate

Conditions
ConditionsYield
at 60℃; for 4h;97%
With perchloric acid; acetic anhydride Esterification;92%
at 55℃; for 24h; Inert atmosphere;92%
cholic acid
81-25-4

cholic acid

methyl iodide
74-88-4

methyl iodide

methyl cholate
1448-36-8

methyl cholate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;97%
With cesium fluoride In N,N-dimethyl-formamide
cholic acid
81-25-4

cholic acid

bromoacetic acid methyl ester
96-32-2

bromoacetic acid methyl ester

methoxycarbonylmethyl cholate
866037-65-2

methoxycarbonylmethyl cholate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 15h;97%
1-Tetradecanol
112-72-1

1-Tetradecanol

cholic acid
81-25-4

cholic acid

tetradecyl 3α,7α,12α-trihydroxy-5β-cholanate
299187-00-1

tetradecyl 3α,7α,12α-trihydroxy-5β-cholanate

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 40 - 50℃; for 15h;97%
With lipase from the fungus rhizomucor miehei In di-isopropyl ether at 40℃; for 48h; Enzymatic reaction;54%
cholic acid
81-25-4

cholic acid

9H-fluoren-9-ylmethyl N-(4-aminobutyl)carbamate hydrochloride

9H-fluoren-9-ylmethyl N-(4-aminobutyl)carbamate hydrochloride

C43H60N2O6

C43H60N2O6

Conditions
ConditionsYield
Stage #1: cholic acid With O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 0.333333h;
Stage #2: 9H-fluoren-9-ylmethyl N-(4-aminobutyl)carbamate hydrochloride In N,N-dimethyl-formamide for 4h;
97%
cholic acid
81-25-4

cholic acid

betaine
107-43-7

betaine

betainium cholate

betainium cholate

Conditions
ConditionsYield
In ethanol at 25℃; for 0.5h;97%
cholic acid
81-25-4

cholic acid

tert-butyl alcohol
75-65-0

tert-butyl alcohol

(3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-oic acid 1,1-dimethylethyl ester
122752-67-4

(3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-oic acid 1,1-dimethylethyl ester

Conditions
ConditionsYield
Stage #1: cholic acid With trifluoroacetic anhydride In tetrahydrofuran at 0 - 20℃; for 1.5h;
Stage #2: tert-butyl alcohol In tetrahydrofuran at 0 - 20℃; for 7h;
Stage #3: With ammonium hydroxide In tetrahydrofuran; water at 0 - 20℃; for 16h;
96.7%
With toluene-4-sulfonic acid; sodium sulfate In 1,4-dioxane for 0.166667h; microwave irradiation;93%
Stage #1: cholic acid With trifluoroacetic anhydride In tetrahydrofuran at 0 - 20℃; for 1.5h;
Stage #2: tert-butyl alcohol In tetrahydrofuran at 20℃; for 7h;
92%
With ammonium hydroxide; trifluoroacetic anhydride Yield given. Multistep reaction;
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