Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:1448-36-8
Min.Order:1 Kilogram
Negotiable
Type:Manufacturers
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:1448-36-8
Min.Order:1
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Type:Other
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:1448-36-8
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryDayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:1448-36-8
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:1448-36-8
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:1448-36-8
Min.Order:1 Kilogram
FOB Price: $9.0 / 99.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:1448-36-8
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:1448-36-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryCHOLIC ACID METHYL ESTER CAS:1448-36-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i
Cas:1448-36-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:1448-36-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:1448-36-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:1448-36-8
Min.Order:0
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Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:1448-36-8
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:1448-36-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in
Cas:1448-36-8
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquirymethyl cholateAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air
Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
Cas:1448-36-8
Min.Order:0
Negotiable
Type:Manufacturers
inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou
Cas:1448-36-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:1448-36-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAmoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi
Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China
Cas:1448-36-8
Min.Order:0
Negotiable
Type:Trading Company
inquiryMethyl cholate cas 1448-36-8Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:1448-36-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta
Cas:1448-36-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry*stable and better quality products*efficient and meticulous servicesAppearance:Powder Storage:Store in dry, cool and ventilated place Package:1kg/tin 5kg/tin 25kg/carton Application:Pharmaceutical raw materials, making injection powder oral agent Tr
good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:5g Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any port
Conditions | Yield |
---|---|
With diazomethyl-trimethyl-silane In methanol; toluene at 20℃; for 2h; | 100% |
With acetyl chloride at 20℃; for 72h; | 100% |
With acetyl chloride at 20℃; for 0.75h; | 100% |
Conditions | Yield |
---|---|
In tetrahydrofuran | A 100% B n/a |
Conditions | Yield |
---|---|
In methanol; hexane; toluene at 20℃; | 100% |
Conditions | Yield |
---|---|
In methanol for 12.5h; Cooling with ice; | 99% |
In methanol |
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20℃; | 97% |
With cesium fluoride In N,N-dimethyl-formamide |
7-α,12-α-dihydroxycholin-4-ene-3-one carboxylic acid methyl ester
A
methyl 3β,7α,12α-trihydroxy-5α-cholan-24-oate
B
methyl cholate
Conditions | Yield |
---|---|
With sodium tetrahydroborate In pyridine for 20h; Ambient temperature; | A 77% B 23% |
With sodium tetrahydroborate In pyridine for 20h; Ambient temperature; | A 77% B 23% |
methyl 3α,7α-diacetoxy-12α-hydroxy cholanate
B
Methyl 12α-hydroxy-5β-cholanate
C
methyl 7α,12a-dihydroxy-5β-cholan-24-oate
D
methyl cholate
Conditions | Yield |
---|---|
With potassium Sodium; iso-butanol; Tris(3,6-dioxaheptyl)amine In tetrahydrofuran Ambient temperature; var. cat.: 18-crown-6; Yield given. Yields of byproduct given; | A n/a B 58% C n/a D n/a |
methyl 3α,7α-diacetoxy-12α-hydroxy cholanate
A
Methyl 12α-hydroxy-5β-cholanate
B
methyl deoxycholate
C
methyl 7α,12a-dihydroxy-5β-cholan-24-oate
D
methyl cholate
Conditions | Yield |
---|---|
With potassium Sodium; iso-butanol; Tris(3,6-dioxaheptyl)amine In tetrahydrofuran Ambient temperature; var. cat.: 18-crown-6; Yields of byproduct given; | A 58% B n/a C n/a D n/a |
Conditions | Yield |
---|---|
With methanol; sodium tetrahydroborate |
methyl 3α,7α-dihydroxy-12-oxo-5β-cholan-24-oate
A
methyl cholate
Conditions | Yield |
---|---|
With borane tert-butylamine In methanol for 3h; Ambient temperature; Yield given. Yields of byproduct given; |
3α-ethoxycarbonyloxy-7α,12α-dihydroxy-5β-cholan-24-oic acid methyl ester
A
methyl cholate
B
methyl 3α,12α-dihydroxy-7-oxo-5β-cholanate
Conditions | Yield |
---|---|
With N-Bromosuccinimide Multistep reaction; |
Conditions | Yield |
---|---|
at 85℃; Rate constant; Kinetics; Thermodynamic data; Heating; Ea; var. temp.; |
methyl cholate
Conditions | Yield |
---|---|
With methanol; sodium tetrahydroborate |
A
methyl cholate
B
3β,7α,12α-trihydroxy-5β-cholan-24-oic acid methyl ester
Conditions | Yield |
---|---|
With methanol; sodium tetrahydroborate |
3-oxo cholic acid methyl ester
methyl cholate
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 25 percent / DDQ / dioxane / 10 h / Heating 2: H2 / tris(triphenylphosphine)-rhodium chloride / benzene 3: 23 percent / NaBH4 / pyridine / 20 h / Ambient temperature View Scheme | |
Multi-step reaction with 4 steps 1: 25 percent / DDQ / dioxane / 10 h / Heating 2: NaBH4 / methanol / 2 h / Ambient temperature 3: MnO2 / CHCl3 / 60 h 4: 23 percent / NaBH4 / pyridine / 20 h / Ambient temperature View Scheme |
methyl 3-oxo-7α,12α-dihydroxy-1,4-choladienate
methyl cholate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: H2 / tris(triphenylphosphine)-rhodium chloride / benzene 2: 23 percent / NaBH4 / pyridine / 20 h / Ambient temperature View Scheme | |
Multi-step reaction with 3 steps 1: NaBH4 / methanol / 2 h / Ambient temperature 2: MnO2 / CHCl3 / 60 h 3: 23 percent / NaBH4 / pyridine / 20 h / Ambient temperature View Scheme |
(R)-4-((7R,8R,9S,10R,12S,13R,14S,17R)-3,7,12-Trihydroxy-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-pentanoic acid methyl ester
methyl cholate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: MnO2 / CHCl3 / 60 h 2: 23 percent / NaBH4 / pyridine / 20 h / Ambient temperature View Scheme |
Conditions | Yield |
---|---|
In methanol |
Conditions | Yield |
---|---|
With hydrogenchloride In methanol at 20℃; for 12h; |
Conditions | Yield |
---|---|
With pyridinium dichromate | 100% |
With pyridinium dichromate | 100% |
With pyridinium dichromate | 100% |
Conditions | Yield |
---|---|
With pyridine; dmap at 20℃; for 1h; | 100% |
With pyridine; dmap at 20℃; for 1h; | 100% |
With pyridine; dmap at 20℃; for 3h; | 98% |
methyl n-dodecanoate
methyl cholate
Dodecanoic acid (3R,5R,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-dihydroxy-17-((R)-3-methoxycarbonyl-1-methyl-propyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester
Conditions | Yield |
---|---|
at 60℃; under 8 Torr; for 20h; Candida antarctica lipase immobilized on Florisil with Triton X-100; | 100% |
Conditions | Yield |
---|---|
at 60℃; under 8 Torr; for 20h; Candida antarctica lipase immobilized on Florisil with Triton X-100; | 100% |
Conditions | Yield |
---|---|
at 60℃; under 8 Torr; for 20h; Candida antarctica lipase immobilized on Florisil with Triton X-100; | 99% |
Conditions | Yield |
---|---|
With potassium hydroxide In methanol; water for 0.0666667h; microwave irradiation; | 99% |
methyl cholate
tert-butyldimethylsilyl chloride
methyl 3α-O-(tert-butyl-dimethylsilanyloxy)-7α,12α-dihydroxy-5β-cholan-24-oate
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 2h; | 99% |
With pyridine; 1H-imidazole In dichloromethane at 50℃; for 18h; | 99% |
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 3h; | 92% |
methyl cholate
3-oxo cholic acid methyl ester
Conditions | Yield |
---|---|
With Ag2CO3 on Celite In toluene Reflux; Inert atmosphere; | 98% |
With silver carbonate In toluene for 12h; Reflux; Dean-Stark; | 94% |
With 4-methyl-morpholine; 6C6H15P*4CF3O3S(1-)*2Ru(2+); acetone at 35℃; for 4h; Inert atmosphere; Sealed tube; | 94% |
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride In tetrahydrofuran | 98% |
With lithium aluminium tetrahydride In tetrahydrofuran for 48h; Heating / reflux; | 98% |
With lithium aluminium tetrahydride In tetrahydrofuran for 48h; Heating / reflux; | 98% |
methyl cholate
ethylenediamine
N-(2-aminoethyl)(3α,5β,7α,12α)-3,7,12-trihydroxycholan-24-amide
Conditions | Yield |
---|---|
In methanol at 20℃; for 48h; | 98% |
In methanol at 69 - 71℃; | 93% |
at 73℃; for 16h; | 93% |
methyl cholate
chloromethyl methyl ether
methyl 3α,7α,12α-tri(methoxymethoxy)-5β-cholan-24-oate
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In benzene at 20℃; for 240h; | 98% |
Conditions | Yield |
---|---|
at 20℃; for 72h; | 96% |
With perchloric acid at 50℃; for 1.5h; | 86% |
Conditions | Yield |
---|---|
With pyridine at -10 - -6℃; for 15h; | 95.3% |
methyl cholate
dimethyl sulfoxide
3α,7α,12α-trihydroxy-24-methylsulfinylmethyl-5β-cholan-24-one
Conditions | Yield |
---|---|
With sodium hydride In tetrahydrofuran at 0℃; for 0.666667h; | 95% |
methyl cholate
methanesulfonyl chloride
Methyl 3α-methanesulphonyloxy-7α,12α-dihydroxy-5β-cholan-24-oate
Conditions | Yield |
---|---|
With pyridine; dmap at 20℃; Cooling with ice; | 95% |
With triethylamine In dichloromethane at 0℃; for 0.166667h; | 87% |
With triethylamine In dichloromethane at 0 - 20℃; for 2.5h; Inert atmosphere; | 84% |
1,6-Hexanediamine
methyl cholate
N-hexylamino-3α,7α,12α-trihydroxy-5β-cholan-24-cholanoamide
Conditions | Yield |
---|---|
In methanol at 69 - 71℃; | 95% |
at 73℃; for 16h; | 95% |
bis(trichloromethyl) carbonate
methyl cholate
Conditions | Yield |
---|---|
With pyridine In benzene at 25℃; for 24h; | 95% |
methyl cholate
methyl iodide
methyl 3α,7α-dimethoxy-12α-hydroxy-5β-cholan-24-oate
Conditions | Yield |
---|---|
With sodium hydride In tetrahydrofuran at 20℃; | 94% |
With sodium hydride In tetrahydrofuran at 20℃; for 12h; | 94% |
Stage #1: methyl cholate With sodium hydride In tetrahydrofuran at 0℃; for 0.25h; Inert atmosphere; Stage #2: methyl iodide In tetrahydrofuran at 20℃; for 24h; Inert atmosphere; | 94% |
methyl cholate
acetic anhydride
methyl 3α,7α-diacetoxy-12α-hydroxy cholanate
Conditions | Yield |
---|---|
With dmap; triethylamine In dichloromethane at 25℃; for 5h; | 92% |
With dmap; triethylamine In dichloromethane at 28℃; | 92% |
With dmap; triethylamine In dichloromethane at 0 - 28℃; | 92% |
methyl cholate
ethanolamine
N-(2-hydroxyethyl)-3α,7α,12α-trihydroxy-5β-cholan-24-amide
Conditions | Yield |
---|---|
In methanol Heating; | 92% |
methyl cholate
methanesulfonyl chloride
methyl 3α-methanesulfonyl-7α,12α-dihydroxy-5β-cholan-24-oate
Conditions | Yield |
---|---|
With pyridine at 20℃; Inert atmosphere; | 92% |
methyl cholate
p-toluenesulfonyl chloride
7α,12α-dihydroxy-3α-(toluene-sulfonyl-(4)-oxy)-5β-cholanoic acid-(24)-methyl ester
Conditions | Yield |
---|---|
In pyridine; benzene Ambient temperature; | 91% |
In pyridine at 10℃; for 16h; | 90% |
With pyridine | 88% |
Conditions | Yield |
---|---|
In chloroform for 16h; | 91% |
Conditions | Yield |
---|---|
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 40℃; for 24h; | 90% |
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 40 - 50℃; for 24h; | |
With dmap; triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; for 48h; Mitsunobu reaction; | |
With dmap; di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 40℃; for 8h; Mitsunobu Displacement; | |
With di-isopropyl azodicarboxylate; triphenylphosphine |
Conditions | Yield |
---|---|
In methanol at 65℃; for 72h; | 89% |
at 20℃; for 168h; |
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