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Kono Chem Co.,Ltd

Appearance:White crystalline powder Storage:Sealed,light and oxygen resistant Package:Foil bag or drum Application:Applied in dietary supplements,pharmaceutical or cosmeticeuticals Transportation:by sea or air Port:Beijing or Guangzh

Top quality Chenodeoxycholic acid 99%

Cas:474-25-9

Min.Order:1 Kilogram

FOB Price: $250.0 / 260.0

Type:Other

inquiry

Xi'an Quanao Biotech Co., Ltd.

Professional Factory We has a complete production and operating system, with an annual output capacity of 2000 tons. It can produce variety of content and proportion of extract according to the demand . Excellent Team We are a young and profess

Factory supply chenodeoxycholic acid powder

Cas:474-25-9

Min.Order:1 Kilogram

FOB Price: $280.0

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Chenodeoxycholic acid Manufacturer/High quality/Best price/In stock

Cas:474-25-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hubei Vanz Pharm Co.,Ltd

Hubei Vanz Pharm Co., Ltd, which the manufacture of APIs, supplements raw powder and some customization products. is located in Wuhan, Hubei province. We are one of the most professional company in pharm/chmecial industry for more than 10 years. W

Chenodeoxycholic acid CAS 474-25-9 CDCA

Cas:474-25-9

Min.Order:1 Gram

FOB Price: $10.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White or almost crystalline powder Storage:Refrigerator Packa

EP standard Chenodeoxycholic acid CAS 474-25-9 supplied by manufacturer

Cas:474-25-9

Min.Order:1 Kilogram

FOB Price: $200.0 / 300.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Chenodeoxycholic acid

Cas:474-25-9

Min.Order:1

Negotiable

Type:Other

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shanghai Tauto Biotech Co., Ltd

17-year experience in Phytochemicals Each product has passed very strict tests (NMR\MS\HPLC) Agents in 13 countries Certified by ISO 9001:2008 quality management system Leader Supplier of Botanical Reference Materials in China

Chenodesoxycholic acid

Cas:474-25-9

Min.Order:10 Milligram

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Chenodeoxycholic acid 474-25-9 GMP Manufacturer

Cas:474-25-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chengdu Lemeitian Pharmaceutical Technology Co,. Ltd

ADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,

Chenodeoxycholic acid

Cas:474-25-9

Min.Order:10 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Chenodeoxycholic acid

Cas:474-25-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hubei DiBo chemical co., LTD

Name:Chenodeoxycholic acid CAS no:474-25-9 Grade:Medical, scientific research and export Molecular formula:C24H40O4 Molecular weight:392.57 Product Quality 12 years of chemical raw materials Mature operation of the industry System stabilit

Chenodeoxycholic acid/cas:474-25-9/high quality/Chenodeoxycholic acid material

Cas:474-25-9

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Leader Biochemical Group

Product Specification Items Specification Appearance White or yellowish crystalline powder Assay (by HPLC) ≥98 .0% Loss on Drying

China Largest Factory Manufacturer Supply Chenodeoxycholic Acid (CDCA) CAS 474-25-9 Annual 200MT

Cas:474-25-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Chenodeoxycholic acid

Cas:474-25-9

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 474-25-9 with best quality

Cas:474-25-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developmen

Chenodeoxycholic acid CAS NO.474-25-9

Cas:474-25-9

Min.Order:1 Kilogram

FOB Price: $2.0 / 6.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hot Sell Factory Supply Raw Material CAS 474-25-9 Chenodeoxycholic acid

Cas:474-25-9

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Chenodeoxycholic acid/ LIDE PHARMA- Factory supply / Best price

Cas:474-25-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Product name Chenodeoxycholic acid CAS NO. 474-25-9 Grade Food grade Apperance White powder Storage Cool Dry Place Appearance: White powder Storage:Store in cool and dry place, away f

Chenodeoxycholic acid

Cas:474-25-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

100% Natural Chenodeoxycholic Acid 474-25-9 Digestive System Medication

Cas:474-25-9

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Chenodeoxycholic acid 474-25-9

Cas:474-25-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

We have two GMP facilities in Hubei Province and cooperative factories in Zhejiang Province We are concentrating on the R&D and technical service of APIs and pharmaceutical intermediates FDA Approved Appearance:White to off-white Storage:

High Quality 99% Chenodeoxycholic Acid Powder CAS 474-25-9 with Wholesale Price

Cas:474-25-9

Min.Order:1 Kilogram

FOB Price: $180.0

Type:Trading Company

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Chenodeoxycholic acid 99%

Cas:474-25-9

Min.Order:1 Kilogram

FOB Price: $86.0 / 98.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Beluga chemical professional supply High quality Chenodeoxycholic acid CAS 474-25-9 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Made in C

High quality Chenodeoxycholic acid CAS 474-25-9

Cas:474-25-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Chenodeoxycholic acid

Cas:474-25-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,

Chenodeoxycholic acid CAS NO.: 474-25-9

Cas:474-25-9

Min.Order:20 Metric Ton

Negotiable

Type:Trading Company

inquiry

Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products wi

Competitive price API CDCA CAS 474-25-9 Chenodeoxycholic Acid

Cas:474-25-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

Chenodeoxycholic Acid cas474-25-9

Cas:474-25-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Purestar Chem Enterprise Co.,Ltd

chenodeoxycholic acid [474-25-9] Product Name: chenodeoxycholic acid Synonyms: 3alpha,7alpha-Dihydroxy-5beta-cholanic acid; Chenodiol; CDCA; (3alpha,5beta,7alpha,8xi,9xi,14xi)-3,7-dihydroxycholan-2

Chenodeoxycholic acid

Cas:474-25-9

Min.Order:1 Kilogram

FOB Price: $6.0

Type:Trading Company

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: Chenodeoxycholic acid Synonyms: henodeoxycholic acid;obeticholic acid Imputity 1;Ursodeoxycholic Acid Impurity 1(Ursodeoxycholic Acid EP Impurity A);URSODEOXYCHOLOC ACID;3,7-dihydroxy-,(3-alpha,5-beta,7-alpha)-cholan-24-oicaci;3,7-

Chenodeoxycholic acid free sample available best quality

Cas:474-25-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

3α,7α-Dihydroxy-chol-11-ensaeure

3α,7α-Dihydroxy-chol-11-ensaeure

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With palladium on activated charcoal; hydrogen In methanol at 70℃; under 30003 Torr; for 12h;99%
(4R)-methyl 4-((3R,5R,7R,10S,13R,17R)-3-acetoxy-7-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
19684-68-5

(4R)-methyl 4-((3R,5R,7R,10S,13R,17R)-3-acetoxy-7-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With water; sodium hydroxide In methanol for 1h; Reflux;97%
With water; sodium hydroxide In methanol; water for 2h; Reagent/catalyst; Reflux;97%
With sodium hydroxide In tetrahydrofuran; methanol; water at 70℃; for 3h;95%
7-Ketolithocholic acid
4651-67-6

7-Ketolithocholic acid

A

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

B

ursodeoxycholic acid
128-13-2

ursodeoxycholic acid

Conditions
ConditionsYield
Stage #1: 7-Ketolithocholic acid With potassium tert-butylate; palladium(II) hydroxide; potassium hydroxide In isopropyl alcohol at 20℃; for 0.166667h;
Stage #2: With hydrogen In isopropyl alcohol at 40 - 80℃; Reagent/catalyst; Temperature;
A n/a
B 95%
With sodium tetrahydroborate; sodium hydrogencarbonate In water at 20℃; for 0.5h; var. reducing agents;A 94%
B 2%
With potassium In tert-butyl alcohol for 0.5h; Heating; var. reducing agents;A 6%
B 94%
7-Ketolithocholic acid
4651-67-6

7-Ketolithocholic acid

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol at 0℃; for 2h;93%
(4R)-methyl 4-((3R,5S,7R,10S,13R,17R)-7-acetoxy-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
93701-16-7

(4R)-methyl 4-((3R,5S,7R,10S,13R,17R)-7-acetoxy-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With water; sodium hydroxide In methanol for 6h; Reflux;90.9%
3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid
2458-08-4

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With potassium hydroxide; hydrazine In 2-methoxy-ethanol; water at 110 - 135℃; for 12h; Wolff-Kishner reduction;90%
With potassium hydroxide; ethylene glycol weiteres Reagens: N2H4;
With potassium hydroxide; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol weiteres Reagens: N2H4;
methyl 3α,7α-diacetoxy-5β-cholan-24-oate
2616-71-9

methyl 3α,7α-diacetoxy-5β-cholan-24-oate

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
Stage #1: methyl 3α,7α-diacetoxy-5β-cholan-24-oate With sodium hydroxide In dichloromethane at 20 - 30℃; for 1h;
Stage #2: With sulfuric acid
87.8%
In methanol; isopropyl alcohol reflux 4 h then RT;69%
With potassium hydroxide
methyl 3α,7α-diacetoxy-12-one-5β-cholest-24-carboxylate
28535-81-1

methyl 3α,7α-diacetoxy-12-one-5β-cholest-24-carboxylate

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With hydrazine hydrate; potassium hydroxide In ethylene glycol at 120 - 210℃; for 5h;86.6%
With sodium ethanolate; hydrazine hydrate at 160℃;
With hydrazine hydrate; potassium hydroxide In 2,2'-[1,2-ethanediylbis(oxy)]bisethanol at 120 - 210℃; for 4h; Wolff-Kishner Reduction; Large scale;
Stage #1: methyl 3α,7α-diacetoxy-12-one-5β-cholest-24-carboxylate With hydrazine hydrate; potassium hydroxide In 2,2'-[1,2-ethanediylbis(oxy)]bisethanol at 120℃; for 2h;
Stage #2: at 210℃; for 3h;
Multi-step reaction with 2 steps
1: Alkaline conditions
View Scheme
ethyl 3α-benzoyloxy-7α-hydroxy-chol-5-en-24-oate

ethyl 3α-benzoyloxy-7α-hydroxy-chol-5-en-24-oate

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
Stage #1: ethyl 3α-benzoyloxy-7α-hydroxy-chol-5-en-24-oate With palladium 10% on activated carbon; hydrogen; acetic acid In ethanol under 2844.39 Torr; for 24h;
Stage #2: With methanol; sodium hydroxide for 18h; Reflux;
82%
C29H48O5

C29H48O5

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With water; sodium hydroxide In methanol at 80℃; for 4h;30%
ethyl chenodeoxycholate acid 7-acetate

ethyl chenodeoxycholate acid 7-acetate

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With water; sodium hydroxide In methanol at 75℃; for 6h;28%
C29H46O5

C29H46O5

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With water; sodium hydroxide In methanol at 75℃; for 5h;28%
C33H48O5

C33H48O5

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With water; sodium hydroxide In methanol at 60℃; for 8h;26%
3,7-diketocholanic acid
859-97-2

3,7-diketocholanic acid

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With ethanol; platinum Hydrogenation;
With acetic acid; platinum Hydrogenation;
With sodium tetrahydroborate; water; sodium hydroxide
3,7-diketocholanic acid
859-97-2

3,7-diketocholanic acid

A

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

B

ursodeoxycholic acid
128-13-2

ursodeoxycholic acid

Conditions
ConditionsYield
With aluminum isopropoxide; isopropyl alcohol
7-Ketolithocholic acid
4651-67-6

7-Ketolithocholic acid

sodium ethanolate
141-52-6

sodium ethanolate

A

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

B

ursodeoxycholic acid
128-13-2

ursodeoxycholic acid

Conditions
ConditionsYield
at 200℃;
methyl 3α-hydroxy-7α-acetoxy-12-oxocholanate
71837-87-1

methyl 3α-hydroxy-7α-acetoxy-12-oxocholanate

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With potassium hydroxide; ethylene glycol weiteres Reagens: N2H4;
With potassium hydroxide; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol weiteres Reagens: N2H4;
3,7-diketocholanic acid
859-97-2

3,7-diketocholanic acid

aluminum isopropoxide
555-31-7

aluminum isopropoxide

isopropyl alcohol
67-63-0

isopropyl alcohol

A

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

B

ursodeoxycholic acid
128-13-2

ursodeoxycholic acid

3α,7α-dihydroxy-12-oxocholanic acid tosylhydrazone
79580-95-3

3α,7α-dihydroxy-12-oxocholanic acid tosylhydrazone

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With sodium tetrahydroborate In acetic acid for 3h; Ambient temperature;
7-hydroxy-3-(sulfooxy)-(3α,5β,7α)-cholan-24-oic acid
64520-49-6, 68780-68-7, 68780-73-4, 68833-02-3, 124815-69-6, 59132-32-0

7-hydroxy-3-(sulfooxy)-(3α,5β,7α)-cholan-24-oic acid

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With hydrogenchloride In methanol; acetone at 37℃; for 18h; Product distribution; solvolyse methods, var. of temp., solvent, reagent and time;
chenodeoxycholic acid 7-sulfate
59132-31-9

chenodeoxycholic acid 7-sulfate

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With hydrogenchloride; 2,2-dimethoxy-propane In methanol; ethyl acetate at 25℃; for 24h; Product distribution; solvolyse methods, var. of temp., solvent, reagent and time;
Conditions
ConditionsYield
With acetate buffer; glycyrrhizinic acid hydrolase at 45℃; hydrolysis; other enzyme (β-glucuronidase);
(25RS)-3α,7α-dihydroxy-5β-cholestan-26-oic acid
17974-66-2

(25RS)-3α,7α-dihydroxy-5β-cholestan-26-oic acid

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
rat liver homogenate, NAD, pH=8.5;
3α,7α,24-trihydroxy-5β-cholestan-26-oic acid

3α,7α,24-trihydroxy-5β-cholestan-26-oic acid

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
rat liver homogenate, NAD, pH=8.5;
(E)-(R)-6-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-2-methyl-hept-2-enoic acid

(E)-(R)-6-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-2-methyl-hept-2-enoic acid

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
rat liver homogenate, NAD, pH=8.5;
6A,6C-bis(2-naphthylsulfonyl)-γ-cyclodextrin chenodeoxycholic acid 1:1 complex

6A,6C-bis(2-naphthylsulfonyl)-γ-cyclodextrin chenodeoxycholic acid 1:1 complex

A

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

B

6A,6C-bis(2-naphthylsulfonyl)-γ-cyclodextrin

6A,6C-bis(2-naphthylsulfonyl)-γ-cyclodextrin

Conditions
ConditionsYield
In water; ethylene glycol at 25℃; Equilibrium constant; decomplexation;
6A,6D-bis(2-naphthylsulfonyl)-γ-cyclodextrin chenodeoxycholic acid 1:1 complex

6A,6D-bis(2-naphthylsulfonyl)-γ-cyclodextrin chenodeoxycholic acid 1:1 complex

A

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

B

6A,6D-bis(2-naphthylsulfonyl)-γ-cyclodextrin

6A,6D-bis(2-naphthylsulfonyl)-γ-cyclodextrin

Conditions
ConditionsYield
In water; ethylene glycol at 25℃; Equilibrium constant; decomplexation;
6A,6E-bis(2-naphthylsulfonyl)-γ-cyclodextrin chenodeoxycholic acid 1:1 complex

6A,6E-bis(2-naphthylsulfonyl)-γ-cyclodextrin chenodeoxycholic acid 1:1 complex

A

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

B

6A,6E-bis(2-naphthylsulfonyl)-γ-cyclodextrin

6A,6E-bis(2-naphthylsulfonyl)-γ-cyclodextrin

Conditions
ConditionsYield
In water; ethylene glycol at 25℃; Equilibrium constant; decomplexation;
3α,7α-diacetoxy-12-oxo-5β-cholan-24-oic acid methyl ester

3α,7α-diacetoxy-12-oxo-5β-cholan-24-oic acid methyl ester

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Conditions
ConditionsYield
With potassium hydroxide; ethylene glycol weiteres Reagens: N2H4;
With potassium hydroxide; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol weiteres Reagens: N2H4;
methanol
67-56-1

methanol

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

chenodeoxycholic acid methyl ester
3057-04-3

chenodeoxycholic acid methyl ester

Conditions
ConditionsYield
With thionyl chloride100%
With toluene-4-sulfonic acid at 20℃; for 1h;100%
With toluene-4-sulfonic acid for 2h; Reflux; Inert atmosphere;100%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

Dehydrochenodeoxycholic acid
4185-00-6

Dehydrochenodeoxycholic acid

Conditions
ConditionsYield
With dipotassium hydrogenphosphate; D-glucose; Pseudomonas paucimobilis; yeast extracxt; peptone In water at 28℃; for 24h;100%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

diazomethyl-trimethyl-silane
18107-18-1

diazomethyl-trimethyl-silane

chenodeoxycholic acid methyl ester
3057-04-3

chenodeoxycholic acid methyl ester

Conditions
ConditionsYield
In methanol; hexane; toluene at 20℃;100%
N-Methyltaurine
107-68-6

N-Methyltaurine

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

3α,7α-dihydroxy-5β-cholan-24-oyl-N-methyltaurine
93790-68-2

3α,7α-dihydroxy-5β-cholan-24-oyl-N-methyltaurine

Conditions
ConditionsYield
With triethylamine; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride In N,N-dimethyl-formamide at 20℃; for 1h;100%
methanol
67-56-1

methanol

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

C26H44O4

C26H44O4

Conditions
ConditionsYield
100%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

acetic anhydride
108-24-7

acetic anhydride

3α,7α-diacetoxy-24-phenyl-5β-cholan-24-oic acid
33628-52-3

3α,7α-diacetoxy-24-phenyl-5β-cholan-24-oic acid

Conditions
ConditionsYield
With pyridine at 20℃; for 24h;99%
With pyridine at 20℃; for 3h;97%
With pyridine at 20℃; for 15h;95%
ethanol
64-17-5

ethanol

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

ethyl 3α,7α-dihydroxy-5β-cholan-24-oate

ethyl 3α,7α-dihydroxy-5β-cholan-24-oate

Conditions
ConditionsYield
With Candida antarctica lipase B In hexane at 55℃; for 24h; Reagent/catalyst; Solvent; Temperature; Time; Enzymatic reaction;99%
With heterologous Rhizopus oryzae lipase immobilized on Octadecyl Sepabeads In di-isopropyl ether at 55℃; Enzymatic reaction;87%
bis(4-methoxyphenyl)amine
101-70-2

bis(4-methoxyphenyl)amine

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

(3R,5S,7R,8R,9S,10S,13R,14S,17R)-17-((R)-4-(bis(4-methoxyphenyl)amino)butan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

(3R,5S,7R,8R,9S,10S,13R,14S,17R)-17-((R)-4-(bis(4-methoxyphenyl)amino)butan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

Conditions
ConditionsYield
With 9-(2-chlorophenyl)acridine; di-tert-butyl peroxide; copper(II) hexafluoroacetylacetonate In ethyl acetate at 35℃; for 24h; Inert atmosphere; Irradiation;99%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

7-Ketolithocholic acid
4651-67-6

7-Ketolithocholic acid

Conditions
ConditionsYield
With dimethyl sulfoxide; triethylamine; trifluoroacetic anhydride In dichloromethane at -30℃; for 1.5h; Temperature; Swern Oxidation;98.6%
With sodium bromate; sulfuric acid; sodium bromide In dichloromethane at 20 - 30℃; for 6h;96.1%
With N-Bromosuccinimide In water; acetone at 20℃; for 2h; Darkness;94%
formic acid
64-18-6

formic acid

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

3α,7α-diformyloxy-5β-cholan-24-oic acid
6159-50-8, 6058-15-7

3α,7α-diformyloxy-5β-cholan-24-oic acid

Conditions
ConditionsYield
With perchloric acid In tetrahydrofuran at 50℃; for 15h;98%
With perchloric acid In tetrahydrofuran; water at 54℃; Inert atmosphere;96%
at 55℃; for 20h;95%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

2,2,2,-trichloroethoxycarbonyl azide

2,2,2,-trichloroethoxycarbonyl azide

2,2,2-trichloroethyl ((3R)-3-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)butyl)carbamate

2,2,2-trichloroethyl ((3R)-3-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)butyl)carbamate

Conditions
ConditionsYield
With dmap; copper diacetate In acetonitrile at 80℃; for 0.166667h; Schlenk technique; Sealed tube;98%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

ethylene diamine mono-p-toluenesulfonic acid salt
14034-59-4

ethylene diamine mono-p-toluenesulfonic acid salt

23-(4,5-dihydroimidazol-2-yl)-24-nor-5β-cholan-3α,7α-diol

23-(4,5-dihydroimidazol-2-yl)-24-nor-5β-cholan-3α,7α-diol

Conditions
ConditionsYield
at 220 - 225℃; for 0.75h;97%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

glycine ethyl ester hydrochloride
5680-79-5

glycine ethyl ester hydrochloride

[(R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoylamino]-acetic acid methyl ester
69320-16-7

[(R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoylamino]-acetic acid methyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide97%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

3,7-diketocholanic acid
859-97-2

3,7-diketocholanic acid

Conditions
ConditionsYield
With sodium bromate; ammonium cerium (IV) nitrate In water; acetonitrile at 80℃; Green chemistry;96%
With potassium bromate; phosphoric acid; potassium bromide In tetrahydrofuran; water; acetonitrile at 20℃; for 3h; Reagent/catalyst; Solvent; Temperature;90.6%
With aluminium(III) chloride hexahydrate; potassium peroxymonosulfate In water at 50℃; for 0.166667h; Microwave irradiation;83%
With chromium(VI) oxide; acetic acid
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

(2-(3)H(N))taurine

(2-(3)H(N))taurine

C26H44(3)HNO6S

C26H44(3)HNO6S

Conditions
ConditionsYield
With hydrogenchloride; tributyl-amine; chloroformic acid ethyl ester In 1,4-dioxane for 0.25h; Ambient temperature;95%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

(1,2-(14)C)taurine

(1,2-(14)C)taurine

C24(14)C2H45NO6S

C24(14)C2H45NO6S

Conditions
ConditionsYield
With hydrogenchloride; tributyl-amine; chloroformic acid ethyl ester In 1,4-dioxane for 0.25h; Ambient temperature;95%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

ferric chenodeoxycholate

ferric chenodeoxycholate

Conditions
ConditionsYield
With iron(III) chloride; sodium hydroxide In water at 35℃; pH=8;95%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

tri-Boc-spermine
114459-62-0

tri-Boc-spermine

N1-(3α,7α-dihydroxy-5β-cholan-24-carbonyl)-(N4,N9N12-tri-tert-butoxycarbonyl)-1,12-diamino-4,9-diazadodecane
287964-36-7

N1-(3α,7α-dihydroxy-5β-cholan-24-carbonyl)-(N4,N9N12-tri-tert-butoxycarbonyl)-1,12-diamino-4,9-diazadodecane

Conditions
ConditionsYield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In dichloromethane at 25℃; for 24h; Acylation;93%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

sodium taurochenodeoxycholate
6009-98-9

sodium taurochenodeoxycholate

Conditions
ConditionsYield
With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; sodium hydroxide In water; acetonitrile; tert-butyl alcohol at 20 - 80℃;93%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

benzyl bromide
100-39-0

benzyl bromide

benzyl 3α,7α-dihydroxy-5β-cholan-24-oate
111992-94-0

benzyl 3α,7α-dihydroxy-5β-cholan-24-oate

Conditions
ConditionsYield
With caesium carbonate In acetonitrile Reflux;92%
With caesium carbonate In acetonitrile for 4h; Reflux;80%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 55℃;
With caesium carbonate In acetonitrile Reflux;
TMSCH2N2

TMSCH2N2

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

methyl (5β,7α)-12-hydroxy-3-oxo-cholan-24-oate
14773-00-3

methyl (5β,7α)-12-hydroxy-3-oxo-cholan-24-oate

Conditions
ConditionsYield
In methanol; diethyl ether; toluene at 20℃; for 0.333333h;91%
1-methyl-piperazine
109-01-3

1-methyl-piperazine

chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

N1<(3α,5β,7α)3,7-dihydroxy-24-oxo-cholan-24-yl>N4methyl-piperazine
86678-67-3

N1<(3α,5β,7α)3,7-dihydroxy-24-oxo-cholan-24-yl>N4methyl-piperazine

Conditions
ConditionsYield
With tributyl-amine; chloroformic acid ethyl ester In 1,4-dioxane 10 deg C, 10 min then rt., 1 h;90%
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

methylamine
74-89-5

methylamine

N methyl(3α,5β,7α)3,7-dihydroxy-cholan-24-amide
86678-62-8

N methyl(3α,5β,7α)3,7-dihydroxy-cholan-24-amide

Conditions
ConditionsYield
With tributyl-amine; chloroformic acid ethyl ester In 1,4-dioxane 10 deg C, 10 min then rt., 1 h;90%
With tributyl-amine; chloroformic acid ethyl ester Multistep reaction;
chenodeoxycholic acid
474-25-9

chenodeoxycholic acid

benzylamine
100-46-9

benzylamine

N benzyl (3α,5β,7α)3,7-dihydroxy-cholan-24-amide
86678-64-0

N benzyl (3α,5β,7α)3,7-dihydroxy-cholan-24-amide

Conditions
ConditionsYield
With tributyl-amine; chloroformic acid ethyl ester In 1,4-dioxane 10 deg C, 10 min then rt., 1 h;90%
With ammonium hydroxide; tributyl-amine; chloroformic acid ethyl ester Multistep reaction;
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