Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:3034-86-4
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryProduct Name: 4-ETHYNYL-BENZOIC ACID METHYL ESTER Synonyms: Methyl-4-Ethylnylbenzoate;Methyl p-ethynylbenzoate;p-Ethynylbenzoic acid methyl ester;Benzoic acid,4-ethynyl-, Methyl ester;Methyl 4-ethynylbenzoate 95%;EOS-62181;4-ETHYNYL-BENZOIC ACID M
Cas:3034-86-4
Min.Order:1 Kilogram
FOB Price: $200.0
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:3034-86-4
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ
Cas:3034-86-4
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry4-ETHYNYL-BENZOIC ACID METHYL ESTER CAS:3034-86-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quali
Cas:3034-86-4
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:3034-86-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryMassive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and
Cas:3034-86-4
Min.Order:1 Gram
FOB Price: $1.0
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:3034-86-4
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquirysuperior quality moderate price & quick delivery Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used to make other chemica
Cas:3034-86-4
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:3034-86-4
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryZhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Cas:3034-86-4
Min.Order:1 Kilogram
FOB Price: $2.0
Type:Lab/Research institutions
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:3034-86-4
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryGOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:3034-86-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirymethyl 4-ethynylbenzoateAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea
Cas:3034-86-4
Min.Order:1 bottle
Negotiable
Type:Lab/Research institutions
inquiryHunan chemfish Pharmaceutical co.,Ltd a comprehensive enterprise, is located in High-Tech Science Park,Changsha,Chia . Specializing in R&D, manufacture and marketing, we provide a wide range of products and the most professional services to meet the
Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service
TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:3034-86-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry"HANGZHOU TIANYE CHEMICALS Co.LTD , Located in Eastern Science and Innovation Park Hangzhou .We are a high-tech enterprise specialized in technical research and development, production, development and trade of chemical products. We supply Multiple s
Benzoic acid,4-ethynyl-, methyl esterAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea, by express
R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou
Cas:3034-86-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirygood quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:250mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any po
Cas:3034-86-4
Min.Order:0
Negotiable
Type:Trading Company
inquiryStock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Our company's tenet is to treat every customer sincerely and be responsible for every product. The production of products according to customer demand for customized, in strict accordance with strict requirements, the production of products alw
Cas:3034-86-4
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Trading Company
inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China
Cas:3034-86-4
Min.Order:0
Negotiable
Type:Trading Company
inquirybulk?production Application:Pharmaceutical intermediates
Cas:3034-86-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirymethyl 4-(3-hydroxy-3-methylbut-1-ynyl)benzoate
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With potassium phosphate; potassium hydroxide In toluene for 0.0833333h; Reagent/catalyst; Time; Inert atmosphere; Reflux; | 100% |
With sodium hydride In toluene at 110℃; | 98% |
With potassium phosphate; potassium carbonate In toluene Inert atmosphere; | 92% |
4-trimethylsilanylethynyl-benzoic acid methyl ester
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With potassium carbonate In methanol for 2h; | 100% |
With tetrabutyl ammonium fluoride In tetrahydrofuran at -20℃; for 0.5h; | 99% |
With potassium carbonate In methanol; dichloromethane | 99% |
(Z)-4-(β-bromovinyl)benzoic acid methyl ester
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide for 1h; microwave irradiation; | 99% |
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide for 0.0166667h; microwave irradiation; | |
With sodium ethanolate In N,N-dimethyl-formamide at 120℃; for 12h; |
methanol
ethyl 4-(trimethylsilylethynyl)benzoate
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With potassium carbonate at 20℃; for 2h; | 99% |
With potassium carbonate at 20℃; for 0.5h; | 91% |
With potassium carbonate at 20℃; for 2h; | 90% |
With potassium carbonate at 10 - 20℃; for 3.86667h; Inert atmosphere; Schlenk technique; | 12.3 g |
Conditions | Yield |
---|---|
With Nonafluorobutanesulfonyl fluoride; tert-butylimino-tri(pyrrolidino)phosphorane In N,N-dimethyl-formamide at -10 - 20℃; | 97% |
methyl 4-iodobenzoate
trimethylsilylacetylene
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
Stage #1: methyl 4-iodobenzoate; trimethylsilylacetylene With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride for 24h; Stage #2: With potassium carbonate In methanol for 48h; | 91% |
Stage #1: methyl 4-iodobenzoate; trimethylsilylacetylene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; triphenylphosphine at 90℃; for 24h; Inert atmosphere; Stage #2: With potassium carbonate In methanol at 20℃; for 3h; Inert atmosphere; | 70% |
Stage #1: methyl 4-iodobenzoate; trimethylsilylacetylene With copper(l) iodide; bis(triphenylphosphine)palladium(II)-chloride; triethylamine In tetrahydrofuran at 70℃; Inert atmosphere; Stage #2: With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 1h; |
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With methylmagnesium bromide In tetrahydrofuran; diethyl ether at -78 - 0℃; for 0.25h; Inert atmosphere; | 91% |
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 22℃; for 1h; | 86% |
dimethyl 1-(1-diazo-2-oxopropyl)phosphonate
methyl 4-formylbenzoate
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With potassium tert-butylate In methanol at 100℃; for 0.5h; | 84% |
With potassium carbonate In tetrahydrofuran; methanol at 20℃; for 12h; | |
With potassium carbonate In tetrahydrofuran; methanol at 20℃; | 23 mg |
4-methoxycarbonylphenyl bromide
trimethylsilylacetylene
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); diisopropylamine at 20℃; for 24.5h; Inert atmosphere; Reflux; | 83.1% |
Stage #1: 4-methoxycarbonylphenyl bromide; trimethylsilylacetylene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 60℃; for 24h; Inert atmosphere; Stage #2: With methanol; potassium hydroxide In tetrahydrofuran at 20℃; for 0.5h; | 30% |
2-methylphenyl aldehyde
allyl-trimethyl-silane
A
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
Stage #1: 2-methylphenyl aldehyde; (4-methoxycarbonylphenyl)ethynyl iodide With bis(cyclopentadienyl)titanium dichloride; P(p-CH3OC6H4)3; zinc In dichloromethane at 20℃; Inert atmosphere; Stage #2: allyl-trimethyl-silane With acetic anhydride In dichloromethane at 0℃; Inert atmosphere; | A n/a B 81% |
4-(methoxycarbonyl)benzyl alcohol
dimethyl 1-(1-diazo-2-oxopropyl)phosphonate
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With manganese(IV) oxide; potassium carbonate In tetrahydrofuran; methanol at 20℃; | 78% |
With manganese(IV) oxide; potassium carbonate In tetrahydrofuran; methanol at 20℃; for 18h; | 78% |
1,1-dibromo-2-(4-methoxycarbonylphenyl)ethene
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With caesium carbonate; dimethyl sulfoxide at 115℃; for 12h; | 78% |
With caesium carbonate In dimethyl sulfoxide at 115℃; Sealed tube; Inert atmosphere; | 33% |
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With potassium carbonate In dimethyl sulfoxide at 115℃; for 12h; | 75% |
Multi-step reaction with 2 steps 1: 99 percent / triethylamine / dimethylformamide / 0.02 h / microwave irradiation 2: 99 percent / 1,8-diazabicyclo[5.4.0]undec-7-ene / dimethylformamide / 1 h / microwave irradiation View Scheme | |
Multi-step reaction with 2 steps 1: triethylamine / dimethylformamide / 1 h / microwave irradiation 2: 1,8-diazabicyclo[5.4.0]undec-7-ene / dimethylformamide / 0.02 h / microwave irradiation View Scheme |
methyl 4-(3-hydroxypropynyl)benzoate
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With manganese(IV) oxide; potassium hydroxide In benzene for 0.25h; Ambient temperature; | 72% |
With manganese(IV) oxide; potassium hydroxide In benzene at 20℃; for 0.25h; | 72% |
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; | 72% |
p-(iodophenyl)carboxaldehyde
trimethylsilylacetylene
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
Stage #1: p-(iodophenyl)carboxaldehyde; trimethylsilylacetylene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; triphenylphosphine at 90℃; for 24h; Sonogashira Cross-Coupling; Inert atmosphere; Stage #2: With potassium carbonate In methanol at 20℃; for 3h; Inert atmosphere; | 70% |
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-di(diphenylphosphino)-butane In dimethyl sulfoxide at 0 - 60℃; for 5h; Sealed flask; | 42% |
methanol
1-carboxamido-4-ethynylbenzene
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With sulfuric acid |
2-ethynyl-1,3-butadiene
propynoic acid methyl ester
A
methyl 3-ethynylbenzoate
B
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
In toluene at 75℃; for 6h; Title compound not separated from byproducts; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: MnO2 / tetrahydrofuran / 4 h / 20 °C 2: 23 mg / K2CO3 / tetrahydrofuran; methanol / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: MnO2 / tetrahydrofuran / 20 °C 2: K2CO3 / methanol; tetrahydrofuran / 12 h / 20 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 97 percent / Pd(PPh3)2Cl2; CuI; triethylamine / 2 h / 20 °C 2: 81 percent / sodium carbonate / methanol / 3 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: 100 percent / (Ph3)2PdCl2; Ph3P; CuI / Et3N / 68 h / Heating 2: 98 percent / NaH / toluene / 110 °C View Scheme | |
Multi-step reaction with 2 steps 1: 95 percent / Pd(PPh3)2Cl2; CuI; triethylamine / tetrahydrofuran / 1.5 h / 80 °C 2: 99 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.5 h / -20 °C View Scheme |
(E)-4-(methoxycarbonyl)cinnamic acid
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: Br2 / CHCl3 2: 99 percent / triethylamine / dimethylformamide / 0.02 h / microwave irradiation 3: 99 percent / 1,8-diazabicyclo[5.4.0]undec-7-ene / dimethylformamide / 1 h / microwave irradiation View Scheme | |
Multi-step reaction with 2 steps 1: chloroform / 20 - 60 °C / Irradiation; Bromination 2: potassium carbonate / dimethyl sulfoxide / 12 h / 115 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 92 percent / CuI; PPh3; Pd(PPh3)2Cl2 / triethylamine; tetrahydrofuran / Heating 2: 99 percent / K2CO3 / methanol; CH2Cl2 View Scheme | |
Multi-step reaction with 2 steps 1: 94 percent Chromat. / PdCl2(1,1'-bis(diphenylphosphino)ferrocene), CuI, Et3N / benzene / 2 h / 70 °C 2: 72 percent / MnO2, KOH powder / benzene / 0.25 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: triethylamine / Pd(OAc)2, PPh3 / tetrahydrofuran / 4 h / Heating 2: Bu4NF / tetrahydrofuran / 0.33 h View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 88 percent / K2CO3 / dimethylsulfoxide 2: 95 percent / Pd(PPh3)2Cl2; CuI; triethylamine / tetrahydrofuran / 1.5 h / 80 °C 3: 99 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.5 h / -20 °C View Scheme | |
Multi-step reaction with 3 steps 1: sulfuric acid / Reflux 2: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 20 °C / Inert atmosphere; Sealed tube; Schlenk technique 3: potassium carbonate / dichloromethane; methanol / 6 h / Inert atmosphere View Scheme | |
Multi-step reaction with 3 steps 1: acetyl chloride / 12 h / 60 °C 2: bis-triphenylphosphine-palladium(II) chloride; triethylamine; copper(l) iodide / 12 h / 75 °C 3: methanol; potassium carbonate / 6 h / 25 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 98 percent / copper(I) iodide; diisopropylethylamine / bis(triphenylphosphine)palladium(II) dichloride / tetrahydrofuran / 18 h / 60 °C 2: 0.49 g / potassium carbonate / methanol; CH2Cl2 / 2 h / 20 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: aq. H2SO4 / 150 °C 2: (i) PCl5, POCl3, (ii) NaNH2, liq. NH3, Et2O 3: H2SO4 View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: (i) PCl5, POCl3, (ii) NaNH2, liq. NH3, Et2O 2: H2SO4 View Scheme |
4-ethynylbenzoic acid methyl ester
1-iodo-2-nitro-4-phenylethynyl-benzene
4-(2-nitro-4-phenylethynylphenylethynyl)benzoic acid methyl ester
Conditions | Yield |
---|---|
With copper(l) iodide; N-ethyl-N,N-diisopropylamine; triphenylphosphine; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran at 20℃; for 1h; Sonogashira-Castro-Stephens coupling; | 100% |
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; triphenylphosphine In tetrahydrofuran for 5h; Inert atmosphere; | 100% |
para-diiodobenzene
4-ethynylbenzoic acid methyl ester
dimethyl 4,4′-[1,4-phenylenebis(ethyne-2,1-diyl)]dibenzoate
Conditions | Yield |
---|---|
Stage #1: 4-ethynylbenzoic acid methyl ester With triethylamine for 0.166667h; Stage #2: para-diiodobenzene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide at 50℃; Inert atmosphere; | 99% |
With copper(l) iodide; bis(triphenylphosphine)palladium(II) chloride In triethylamine at 50℃; Inert atmosphere; | 99% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; Sonogashira cross-coupling reaction; | 46% |
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With aluminum oxide; N-iodo-succinimide In acetonitrile at 80℃; for 1h; Molecular sieve; | 99% |
With N-chlorobenzenesulfonamide; potassium iodide In acetonitrile at 20℃; for 2h; | 97% |
With N-iodo-succinimide; acetic acid In acetonitrile at 80℃; for 1.5h; Molecular sieve; | 97% |
Conditions | Yield |
---|---|
With [(THD-Dipp)AuOTf] In neat (no solvent) at 100℃; Green chemistry; regioselective reaction; | 99% |
Conditions | Yield |
---|---|
With hexa[tri(dimethylamino)phosphazene]cyclotriphosphazene In dimethyl sulfoxide at 120℃; for 24h; Inert atmosphere; Glovebox; stereoselective reaction; | 99% |
4-ethynylbenzoic acid methyl ester
4-Ethynyl-benzoic acid
Conditions | Yield |
---|---|
With water; sodium hydroxide In tetrahydrofuran at 20℃; for 2h; Inert atmosphere; | 98.64% |
With lithium hydroxide In methanol; water for 2h; | 77% |
With lithium hydroxide In methanol; water for 2h; | 77% |
Conditions | Yield |
---|---|
With 5,10,15-tris(pentafluorophenyl)corrole cobalt(III) triphenyl phosphine; sulfuric acid; water In methanol at 80℃; for 36h; | 98% |
With trifluorormethanesulfonic acid; water In 2,2,2-trifluoroethanol at 25 - 70℃; for 45h; Sealed tube; regioselective reaction; | 94% |
With indium(III) triflate; water; toluene-4-sulfonic acid In 1,2-dichloro-ethane for 19h; Sealed tube; Reflux; regioselective reaction; | 77% |
With methanol; platinum(IV) oxide; water; toluene-4-sulfonic acid at 90℃; for 5h; Sealed tube; | 68% |
With 2CHF3O3S*C29H35NO6P2Pt; water; sodium dodecyl-sulfate at 80℃; Micellar solution; | 26 %Chromat. |
2-iodo-4-methoxybromobenzene
4-ethynylbenzoic acid methyl ester
methyl 4-[(2-bromo-5-methoxyphenyl)ethynyl]benzoate
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 20℃; for 4h; Inert atmosphere; | 98% |
4'-azido-2,2'-bipyridine-N'-oxide
4-ethynylbenzoic acid methyl ester
4'-(4-(4-(methoxycarbonyl)phenyl)-1H-1,2,3-triazol-1-yl)-2,2'-bipyridine N'-oxide
Conditions | Yield |
---|---|
With copper(ll) sulfate pentahydrate; sodium L-ascorbate In dichloromethane; water at 20℃; for 20h; Inert atmosphere; | 98% |
Conditions | Yield |
---|---|
With triethylamine In water; tert-butyl alcohol at 50℃; for 7h; Schlenk technique; | 98% |
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 20℃; for 1h; Sonogashira Cross-Coupling; Inert atmosphere; Microwave irradiation; | 98% |
4-ethynylbenzoic acid methyl ester
2-fluoro-5-iodopyridine
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 20℃; for 16h; | 98% |
Conditions | Yield |
---|---|
In(OSO2CF3)3 at 140℃; for 18h; | 97% |
indium(III) triflate at 140℃; for 18h; | 97% |
With indium(III) triflate | 97% |
4-ethynylbenzoic acid methyl ester
benzyl azide
1-benzyl-1H-[1,2,3]triazole-4-carboxylic acid methyl ester
Conditions | Yield |
---|---|
With copper(l) iodide; 1-decylimidazole at 25℃; for 2h; neat (no solvent); | 97% |
5-iodo-1,1,3,3-tetramethyl-1,3-disilaindane
4-ethynylbenzoic acid methyl ester
methyl 4-(1,1,3,3-tetramethyl-1,3-disilaindan-5-ylethynyl)benzoate
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 17h; Sonogashira Cross-Coupling; Inert atmosphere; | 97% |
Conditions | Yield |
---|---|
With oxygen; potassium carbonate; copper(l) chloride In methanol; acetonitrile at 25℃; for 2.5h; Irradiation; Green chemistry; | 97% |
[RuCl(dppe)2]OTf
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; for 1h; Inert atmosphere; Schlenk technique; | 97% |
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With C17H37FeN3P2 In tetrahydrofuran at 20℃; Inert atmosphere; Glovebox; stereoselective reaction; | 97% |
With [CoBr2(TriPhos)]; zinc(II) iodide; zinc In acetonitrile at 0 - 20℃; for 4h; Inert atmosphere; Schlenk technique; diastereoselective reaction; | 67% |
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
Stage #1: 4-ethynylbenzoic acid methyl ester With [bis(acetoxy)iodo]benzene; tetra-(n-butyl)ammonium iodide In acetonitrile at 20℃; for 3h; Stage #2: With [bis(acetoxy)iodo]benzene; potassium iodide In water; acetonitrile at 20℃; for 15h; | 97% |
Stage #1: 4-ethynylbenzoic acid methyl ester With [bis(acetoxy)iodo]benzene; tetra-(n-butyl)ammonium iodide In acetonitrile at 20℃; for 3h; Stage #2: With [bis(acetoxy)iodo]benzene; potassium iodide In water; acetonitrile at 20℃; for 15.3333h; chemoselective reaction; | 91% |
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With water-d2; silver trifluoroacetate In dichloromethane at 25℃; for 16h; | 97% |
4-ethynylbenzoic acid methyl ester
2-bromo-5-(4-n-hexylphenylethynyl)-4-nitro-N-acetylaniline
Conditions | Yield |
---|---|
With copper(l) iodide; N-ethyl-N,N-diisopropylamine; bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran at 75℃; for 72h; Castro-Stephens/Sonogashira coupling; | 96% |
4-ethynylbenzoic acid methyl ester
Conditions | Yield |
---|---|
With copper oxide supported on mesoporous manganese oxide; air In toluene at 105℃; for 4h; | 96% |
With piperidine In toluene at 60℃; under 760.051 Torr; for 24h; | 95% |
With copper diacetate In pyridine at 20℃; for 46h; Eglinton Coupling; Schlenk technique; Inert atmosphere; | 89% |
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine for 3h; Sonogashira cross-coupling reaction; Heating; | 96% |
With copper(l) iodide; bis(triphenylphosphine)palladium(II) chloride In triethylamine at 50℃; Inert atmosphere; | 91% |
4-ethynylbenzoic acid methyl ester
3-butylamino-N,N-dimethyl-(Z)-2-butenamide
Conditions | Yield |
---|---|
Stage #1: 4-ethynylbenzoic acid methyl ester; 3-butylamino-N,N-dimethyl-(Z)-2-butenamide With diethylzinc In hexane at 70℃; for 15h; Stage #2: With hydrogenchloride In tetrahydrofuran; hexane at 20℃; | 96% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View