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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

3,6-Dichlorosalicylic acid Manufacturer/High quality/Best price/In stock

Cas:3401-80-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

huge stock TC herbicide 3,6-DICHLORO-2-HYDROXY BENZOIC ACID 3401-80-7 GLP Manufacturer

Cas:3401-80-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3,6-Dichlorosalicylic acid

Cas:3401-80-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 3401-80-7 with best price

Cas:3401-80-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzoic acid,3,6-dichloro-2-hydroxy- 3401-80-7

Cas:3401-80-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

3,6-DICHLORO-2-HYDROXY BENZOIC ACID CAS:3401-80-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qualit

3,6-DICHLORO-2-HYDROXY BENZOIC ACID CAS:3401-80-7

Cas:3401-80-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzoic acid,3,6-dichloro-2-hydroxy-

Cas:3401-80-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzoic acid,3,6-dichloro-2-hydroxy-

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzoic acid,3,6-dichloro-2-hydroxy-

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 3,6-Dichloro-2-Hydroxybenzoic Acid

Cas:3401-80-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:3, 6 -

Benzoic acid,3,6-dichloro-2-hydroxy-

Cas:3401-80-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

3401-80-7 3,6-DICHLORO-2-HYDROXY BENZOIC ACID

Cas:3401-80-7

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

3,6-Dichlorosalicylic acid

Cas:3401-80-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3,6-Dichloro-2-hydroxybenzoic acid cas no. 3401-80-7 98%

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3,6-Dichloro-2-Hydroxybenzoic Acid

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

3,6-Dichlorosalicylic acid

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 3,6-Dichloro-2-hydroxybenzoic acid 5g

Cas:3401-80-7

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

3,6-Dichloro-2-Hydroxybenzoic Acid

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

3,6-DICHLORO-2-HYDROXY BENZOIC ACID

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

3,6-Dichloro-2-hydroxy benzoic acid

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzoic acid,3,6-dichloro-2-hydroxy-

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

3,6-DICHLORO-2-HYDROXY BENZOIC ACID

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

3,6-Dichlorosalicylic acid cas 3401-80-7Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

3,6-Dichlorosalicylic acid cas 3401-80-7

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3,6-DICHLORO-2-HYDROXY BENZOIC ACID

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta

3,6-DICHLORO-2-HYDROXY BENZOIC ACID

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Asure Biochem CO.,LTD.

*stable and better quality products*efficient and meticulous servicesAppearance:Powder Storage:Store in dry, cool and ventilated place Package:1kg/tin 5kg/tin 25kg/carton Application:Pharmaceutical raw materials, making injection powder oral agent Tr

3,6-Dichloro-2-Hydroxybenzoic Acid

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:1g Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any port

3,6-DICHLORO-2-HYDROXY BENZOIC ACID

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

3401-80-7

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hebei Muhuang Technology Co., Ltd

best seller Application:API

3,6-DICHLORO-2-HYDROXY BENZOIC ACID

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

3,6-Dichloro-2-hydroxy benzoic acid 3401-80-7

Cas:3401-80-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

4-bromo-3,6-dichlorosalicylic acid

4-bromo-3,6-dichlorosalicylic acid

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
at 50℃; for 1h; Alkaline conditions;99%
With tin; sodium hydroxide In water at 50℃; for 1h; Reagent/catalyst; Temperature;98%
Stage #1: 5-bromo-3,6-dichlorosalicylic acid With 5%-palladium/activated carbon; hydrogen In water; ethyl acetate at 20℃; under 760.051 Torr; for 1h;
Stage #2: With sodium hydroxide In water; ethyl acetate for 5h;
77%
3,6-dichloro-2-hydroxybenzaldehyde
27164-09-6

3,6-dichloro-2-hydroxybenzaldehyde

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sodium dihydrogenphosphate; sodium chlorite trihydrate; aminosulfonic acid In 1,4-dioxane; water at 0 - 20℃; for 1h;88%
2,3,6-trichlorobenzoate sodium salt

2,3,6-trichlorobenzoate sodium salt

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With methanol; sodium hydroxide at 130℃; under 6000.6 Torr; for 5h; Temperature; Pressure; Inert atmosphere;80%
carbon dioxide
124-38-9

carbon dioxide

2,5-dichlorophenol
583-78-8

2,5-dichlorophenol

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: 2,5-dichlorophenol With potassium hydroxide; zinc In 5,5-dimethyl-1,3-cyclohexadiene at 130 - 135℃; for 0.5h; Inert atmosphere; Autoclave;
Stage #2: carbon dioxide at 130 - 140℃; under 30003 Torr; Inert atmosphere; Autoclave;
Stage #3: With hydrogenchloride In water at 60 - 80℃; pH=0 - 1; Reagent/catalyst; Solvent; Autoclave;
75.3%
Stage #1: 2,5-dichlorophenol With potassium hydroxide In 5,5-dimethyl-1,3-cyclohexadiene; water
Stage #2: carbon dioxide at 100℃; under 25858.1 Torr; for 3h;
42%
With potassium carbonate at 160℃; under 45004.5 Torr; for 7h; Time; Reagent/catalyst; Kolbe-Schmidt Synthesis;27.7%
With potassium carbonate In 5,5-dimethyl-1,3-cyclohexadiene at 35 - 120℃; under 26252.6 - 37503.8 Torr; for 1.5h;
carbon dioxide
124-38-9

carbon dioxide

potassium salt of 2,5-dichlorophenol
68938-81-8

potassium salt of 2,5-dichlorophenol

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With tetrabutylammomium bromide; potassium carbonate at 160℃; under 45004.5 Torr; for 4h; Time; Reagent/catalyst; Temperature; Pressure; Kolbe-Schmidt Synthesis;52.9%
potassium-<2.5-dichloro-phenolate>

potassium-<2.5-dichloro-phenolate>

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With carbon dioxide at 130 - 140℃; under 29420.3 Torr;
sodium-<2.5-dichloro-phenolate>

sodium-<2.5-dichloro-phenolate>

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With carbon dioxide at 130 - 140℃; under 29420.3 Torr;
diethyl ether
60-29-7

diethyl ether

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sulfuric acid In water
2,5-dichlorophenol
583-78-8

2,5-dichlorophenol

potassium salt of 2,5-dichlorophenol
68938-81-8

potassium salt of 2,5-dichlorophenol

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With potassium hydroxide; carbon dioxide; potassium carbonate In 5,5-dimethyl-1,3-cyclohexadiene; water
3,6-dichloro-O-anisic acid
1918-00-9

3,6-dichloro-O-anisic acid

A

formaldehyd
50-00-0

formaldehyd

B

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With oxygen
4-bromo-3,6-dichlorosalicylic acid

4-bromo-3,6-dichlorosalicylic acid

A

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

B

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen; sodium acetate; acetic acid In water at 20℃; under 760.051 Torr; for 16h; Reagent/catalyst; Solvent; Temperature;
5-bromo-3-chloro-2-hydroxybenzoic acid
2200-85-3

5-bromo-3-chloro-2-hydroxybenzoic acid

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: iodine; sulfur trioxide; chlorine; sulfuric acid / 5.5 h / 5 - 33 °C
2: sodium acetate; 5%-palladium/activated carbon; hydrogen; acetic acid / water; ethyl acetate / 4 h / 20 °C / 760.05 Torr
View Scheme
Multi-step reaction with 2 steps
1.1: chlorine; iodine; sulfuric acid / 3.5 h / 5 - 35 °C
2.1: 5%-palladium/activated carbon; hydrogen / water; ethyl acetate / 1 h / 20 °C / 760.05 Torr
2.2: 5 h
View Scheme
Multi-step reaction with 2 steps
1: sulfur trioxide; iodine / 50 °C
2: 1 h / 50 °C / Alkaline conditions
View Scheme
Multi-step reaction with 2 steps
1: chlorine; sulfur trioxide; iodine / 35 °C
2: tin; sodium hydroxide / 1 h / 50 °C
View Scheme
Multi-step reaction with 2 steps
1: chlorine; sulfur trioxide; iodine / 35 °C
2: potassium hydroxide; zinc / 1 h / 30 °C / Inert atmosphere
View Scheme
5-bromo-3-chloro-2-hydroxybenzoic acid
2200-85-3

5-bromo-3-chloro-2-hydroxybenzoic acid

A

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

B

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: iodine; sulfur trioxide; chlorine; sulfuric acid / 5.5 h / 5 - 33 °C
2: sodium acetate; palladium 10% on activated carbon; hydrogen; acetic acid / water / 16 h / 20 °C / 760.05 Torr
View Scheme
5-bromosalicyclaldehyde
1761-61-1

5-bromosalicyclaldehyde

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: chlorine; acetic acid / 4 h / 20 °C
2: iodine; sulfur trioxide; chlorine; sulfuric acid / 24 h / 35 °C
3: 5%-palladium/activated carbon; hydrogen; potassium acetate; acetic acid / 18 h / 760.05 Torr
4: aminosulfonic acid; sodium dihydrogenphosphate; sodium chlorite trihydrate / water; 1,4-dioxane / 1 h / 0 - 20 °C
View Scheme
5-bromo-3-chloro-2-hydroxybenzaldehyde
19652-33-6

5-bromo-3-chloro-2-hydroxybenzaldehyde

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: iodine; sulfur trioxide; chlorine; sulfuric acid / 24 h / 35 °C
2: 5%-palladium/activated carbon; hydrogen; potassium acetate; acetic acid / 18 h / 760.05 Torr
3: aminosulfonic acid; sodium dihydrogenphosphate; sodium chlorite trihydrate / water; 1,4-dioxane / 1 h / 0 - 20 °C
View Scheme
3-bromo-2,5-dichloro-6-hydroxy-benzaldehyde

3-bromo-2,5-dichloro-6-hydroxy-benzaldehyde

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 5%-palladium/activated carbon; hydrogen; potassium acetate; acetic acid / 18 h / 760.05 Torr
2: aminosulfonic acid; sodium dihydrogenphosphate; sodium chlorite trihydrate / water; 1,4-dioxane / 1 h / 0 - 20 °C
View Scheme
5-bromosalicyclic acid
89-55-4

5-bromosalicyclic acid

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: iodine; sulfur trioxide; sulfuric acid / 5 - 20 °C
1.2: 5 - 30 °C
2.1: sodium acetate; 5%-palladium/activated carbon; hydrogen; acetic acid / water; ethyl acetate / 4 h / 20 °C / 760.05 Torr
View Scheme
Multi-step reaction with 2 steps
1: iodine; trichloroisocyanuric acid; sulfuric acid / 5 h / 0 - 70 °C
2: sodium acetate; 5%-palladium/activated carbon; hydrogen; acetic acid / water; ethyl acetate / 4 h / 20 °C / 760.05 Torr
View Scheme
Multi-step reaction with 3 steps
1.1: sodium hydroxide; sodium hypochlorite / 0 °C
1.2: 5 h / 40 °C
2.1: iodine; sulfur trioxide; chlorine; sulfuric acid / 5.5 h / 5 - 33 °C
3.1: sodium acetate; 5%-palladium/activated carbon; hydrogen; acetic acid / water; ethyl acetate / 4 h / 20 °C / 760.05 Torr
View Scheme
5-bromosalicyclic acid
89-55-4

5-bromosalicyclic acid

A

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

B

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: iodine; trichloroisocyanuric acid; sulfuric acid / 5 h / 0 - 70 °C
2: sodium acetate; palladium 10% on activated carbon; hydrogen; acetic acid / water / 16 h / 20 °C / 760.05 Torr
View Scheme
Multi-step reaction with 3 steps
1.1: sodium hydroxide; sodium hypochlorite / 0 °C
1.2: 5 h / 40 °C
2.1: iodine; sulfur trioxide; chlorine; sulfuric acid / 5.5 h / 5 - 33 °C
3.1: sodium acetate; palladium 10% on activated carbon; hydrogen; acetic acid / water / 16 h / 20 °C / 760.05 Torr
View Scheme
Multi-step reaction with 3 steps
1: iodine; trichloroisocyanuric acid; sulfuric acid / 5 h / 0 - 70 °C
2: iodine; sulfur trioxide; chlorine; sulfuric acid / 5.5 h / 5 - 33 °C
3: sodium acetate; palladium 10% on activated carbon; hydrogen; acetic acid / water / 16 h / 20 °C / 760.05 Torr
View Scheme
salicylic acid
69-72-7

salicylic acid

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: bromine; sulfuric acid / 1 h / 20 - 60 °C
2.1: iodine; sulfur trioxide; sulfuric acid / 5 - 20 °C
2.2: 5 - 30 °C
3.1: sodium acetate; 5%-palladium/activated carbon; hydrogen; acetic acid / water; ethyl acetate / 4 h / 20 °C / 760.05 Torr
View Scheme
Multi-step reaction with 3 steps
1.1: bromine; sulfuric acid / 1 h / 20 °C
2.1: iodine; sulfur trioxide; sulfuric acid / 5 - 20 °C
2.2: 5 - 30 °C
3.1: sodium acetate; 5%-palladium/activated carbon; hydrogen; acetic acid / water; ethyl acetate / 4 h / 20 °C / 760.05 Torr
View Scheme
Multi-step reaction with 3 steps
1.1: bromine; sulfuric acid; acetic acid / 0.5 h / 30 - 60 °C
2.1: iodine; sulfur trioxide; sulfuric acid / 5 - 20 °C
2.2: 5 - 30 °C
3.1: sodium acetate; 5%-palladium/activated carbon; hydrogen; acetic acid / water; ethyl acetate / 4 h / 20 °C / 760.05 Torr
View Scheme
salicylic acid
69-72-7

salicylic acid

A

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

B

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: bromine; sulfuric acid / 1 h / 20 - 60 °C
2.1: iodine; sulfur trioxide; sulfuric acid / 5 - 20 °C
2.2: 5 - 30 °C
3.1: sodium acetate; palladium 10% on activated carbon; hydrogen; acetic acid / water / 16 h / 20 °C / 760.05 Torr
View Scheme
Multi-step reaction with 3 steps
1.1: bromine; sulfuric acid / 1 h / 20 °C
2.1: iodine; sulfur trioxide; sulfuric acid / 5 - 20 °C
2.2: 5 - 30 °C
3.1: sodium acetate; palladium 10% on activated carbon; hydrogen; acetic acid / water / 16 h / 20 °C / 760.05 Torr
View Scheme
Multi-step reaction with 3 steps
1.1: bromine; sulfuric acid; acetic acid / 0.5 h / 30 - 60 °C
2.1: iodine; sulfur trioxide; sulfuric acid / 5 - 20 °C
2.2: 5 - 30 °C
3.1: sodium acetate; palladium 10% on activated carbon; hydrogen; acetic acid / water / 16 h / 20 °C / 760.05 Torr
View Scheme
potassium 3,6-dichloro salicylate

potassium 3,6-dichloro salicylate

potassium carbonate
584-08-7

potassium carbonate

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With hydrogenchloride In water at 40℃; for 0.166667h; pH=1; Temperature; pH-value;
2,5-dichlorophenol
583-78-8

2,5-dichlorophenol

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium hydroxide / 5,5-dimethyl-1,3-cyclohexadiene; water / Inert atmosphere; Reflux
2: 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; potassium carbonate / 5,5-dimethyl-1,3-cyclohexadiene / 1.08 h / 50 - 140 °C / 22502.3 - 41254.1 Torr / Autoclave
3: hydrogenchloride / water / 0.17 h / 40 °C / pH 1
View Scheme
potassium salt of 2,5-dichlorophenol
68938-81-8

potassium salt of 2,5-dichlorophenol

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; potassium carbonate / 5,5-dimethyl-1,3-cyclohexadiene / 1.08 h / 50 - 140 °C / 22502.3 - 41254.1 Torr / Autoclave
2: hydrogenchloride / water / 0.17 h / 40 °C / pH 1
View Scheme
2-methylchlorobenzene
95-49-8

2-methylchlorobenzene

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: antimony(III) chloride; chlorine / 6 h / 25 °C
2: cobalt(II) diacetate tetrahydrate; sodium bromide; oxygen; acetic acid / 8 h / 135 °C / 5250.53 - 6750.68 Torr
3: methanol; sodium hydroxide / 5 h / 130 °C / 6000.6 Torr / Inert atmosphere
View Scheme
2,5 dichloroaniline
95-82-9

2,5 dichloroaniline

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium nitrite; sulfuric acid / water
2.1: potassium hydroxide / water; 5,5-dimethyl-1,3-cyclohexadiene
2.2: 3 h / 100 °C / 25858.1 Torr
View Scheme
1,2,4-Trichlorobenzene
120-82-1

1,2,4-Trichlorobenzene

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: potassium hydroxide / methanol / 7 h / 180 °C / 24321.6 Torr
2.1: potassium hydroxide / water; 5,5-dimethyl-1,3-cyclohexadiene
2.2: 3 h / 100 °C / 25858.1 Torr
View Scheme
para-dichlorobenzene
106-46-7

para-dichlorobenzene

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: nitric acid; sulfuric acid
1.2: 3102.97 Torr
2.1: sodium nitrite; sulfuric acid / water
3.1: potassium hydroxide / water; 5,5-dimethyl-1,3-cyclohexadiene
3.2: 3 h / 100 °C / 25858.1 Torr
View Scheme
ortho-cresol
95-48-7

ortho-cresol

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: bromine / N,N-dimethyl-formamide / 2.5 h / 10 °C / Inert atmosphere
2: chlorine; chlorosulfonic acid; iron(III) chloride / N,N-dimethyl-formamide / 20 °C
3: vanadium(V) oxide; nitric acid / 3 h / 120 °C
4: nickel; copper / water / 1 h / 90 °C / pH 11
View Scheme
4-Bromo-2-methylphenol
2362-12-1

4-Bromo-2-methylphenol

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: chlorine; chlorosulfonic acid; iron(III) chloride / N,N-dimethyl-formamide / 20 °C
2: vanadium(V) oxide; nitric acid / 3 h / 120 °C
3: nickel; copper / water / 1 h / 90 °C / pH 11
View Scheme
methylene chloride
74-87-3

methylene chloride

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

methyl 2,5-dichloro-6-methoxybenzoate
6597-78-0

methyl 2,5-dichloro-6-methoxybenzoate

Conditions
ConditionsYield
Stage #1: 3,6-dichloro-2-hydroxybenzoic acid With sodium hydroxide Industrial scale;
Stage #2: methylene chloride With sodium carbonate In methanol at 95℃; under 3750.38 Torr; for 12h; Industrial scale;
96%
With methanol at 90 - 95℃; for 12h;
With sodium hydroxide In methanol; water at 90 - 95℃; for 12h; Large scale;
methanol
67-56-1

methanol

methylene chloride
74-87-3

methylene chloride

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

methyl 2,5-dichloro-6-methoxybenzoate
6597-78-0

methyl 2,5-dichloro-6-methoxybenzoate

Conditions
ConditionsYield
With tetrabutyl-ammonium chloride at 90 - 95℃; for 12h; Reagent/catalyst;72.8%
3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

6-azaspiro[3.4]octane hydrochloride

6-azaspiro[3.4]octane hydrochloride

(6-azaspiro[3.4]oct-6-yl)(3,6-dichloro-2-hydroxyphenyl)methanone

(6-azaspiro[3.4]oct-6-yl)(3,6-dichloro-2-hydroxyphenyl)methanone

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In tetrahydrofuran at 0 - 20℃; for 16h;18%
3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

3,6-dichloro-O-anisic acid
1918-00-9

3,6-dichloro-O-anisic acid

Conditions
ConditionsYield
With potassium hydroxide; dimethyl sulfate In water
methanol
67-56-1

methanol

3,6-dichloro-2-hydroxybenzoic acid
3401-80-7

3,6-dichloro-2-hydroxybenzoic acid

3,6-dichloro-O-anisic acid
1918-00-9

3,6-dichloro-O-anisic acid

Conditions
ConditionsYield
With tetrabutylammomium bromide; potassium hydroxide at 60℃; under 3000.3 Torr; for 3h; pH=8; Reagent/catalyst; pH-value; Pressure; Temperature;

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