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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

5-Acetylthiophene-2-carboxylic acid Manufacturer/High quality/Best price/In stock

Cas:4066-41-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Acetyl-Thiophene-2-Carboxylic Acid supplier in China

Cas:4066-41-5

Min.Order:1 Metric Ton

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Acetyl-2-thiophenecarboxylic acid

Cas:4066-41-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Leader Biochemical Group

About Product Technical Details 5-Acetylthiophene-2-carboxylic acid Chemical Properties

China Largest factory Manufacturer Supply 5-Acetylthiophene-2-carboxylic acid CAS 4066-41-5

Cas:4066-41-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 4066-41-5 with best quality

Cas:4066-41-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-Acetylthiophene-2-carboxylic acid 4066-41-5

Cas:4066-41-5

Min.Order:1 Kilogram

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Qingdao Beluga Import and Export Co., LTD

5-Acetylthiophene-2-carboxylic acid CAS:4066-41-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quali

5-Acetylthiophene-2-carboxylic acid CAS:4066-41-5

Cas:4066-41-5

Min.Order:1 Gram

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Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:1 Kilogram

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Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several

5-Acetyl-2-thiophenecarboxylic acid cas:4066-41-5

Cas:4066-41-5

Min.Order:25 Gram

FOB Price: $90.0 / 100.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:0

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Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Acetyl-Thiophene-2-Carboxylic Acid

Cas:4066-41-5

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:0 Metric Ton

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Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 5-Acetyl-Thiophene-2-Carboxylic Acid

Cas:4066-41-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: 5-Acetyl-Thiophene-2-Carboxylic Acid CAS No.: 4066-41-5 Molecule Formula:C7H6O3S Molecule Weight:170.19 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard

Lower Price 5-Acetyl-Thiophene-2-Carboxylic Acid on stock

Cas:4066-41-5

Min.Order:1 Kilogram

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Type:Trading Company

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

5-Acetylthiophene-2-carboxylicacid

Cas:4066-41-5

Min.Order:1 Milligram

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:0

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:1 Gram

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Type:Lab/Research institutions

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SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:0

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Cas no.4066-41-5 98% 5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:0

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3-furan-2-ylalanine

Cas:4066-41-5

Min.Order:0

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Type:Other

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air

5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:0

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Type:Manufacturers

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

5-Acetyl-2-thiophenecarboxylic acid

Cas:4066-41-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

5-Acetyl-Thiophene-2-Carboxylic Acid

Cas:4066-41-5

Min.Order:0

Negotiable

Type:Manufacturers

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Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:0

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Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:0

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Type:Lab/Research institutions

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Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

5-Acetylthiophene-2-carboxylic acid

Cas:4066-41-5

Min.Order:0

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Type:Trading Company

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Synthetic route

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

acetyl chloride
75-36-5

acetyl chloride

5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid; acetyl chloride With isopropylmagnesium bromide In tetrahydrofuran at -40 - -10℃; for 12h; Solid phase reaction;
Stage #2: In dichloromethane at 20℃; for 0.25h; Hydrolysis; Further stages.;
90%
2-Acetyl-5-methylthiophen
13679-74-8

2-Acetyl-5-methylthiophen

5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

Conditions
ConditionsYield
With cerium(III) chloride; 1,1,1-trichloroethanol; oxygen In acetonitrile at 60℃; Irradiation;81%
With oxygen; cobalt(II) acetate; sodium bromide In acetic acid at 95℃; for 1.5h; Kinetics; Rate constant;
With oxygen; cobalt(II) acetate; sodium bromide In acetic acid at 100℃; for 1.5h;
2-Acetylthiophene
88-15-3

2-Acetylthiophene

carbon dioxide
124-38-9

carbon dioxide

5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

Conditions
ConditionsYield
With 2,3,6,7-tetramethoxy-9(10H)-anthracenone; caesium carbonate In dimethyl sulfoxide at 25℃; under 2280.15 Torr; for 18h; Irradiation; Sealed tube; regioselective reaction;39%
2-thiophenylcarboxylic acid
527-72-0

2-thiophenylcarboxylic acid

malonic acid
141-82-2

malonic acid

5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

Conditions
ConditionsYield
With PPA at 60 - 80℃; for 2h; Acylation; Friedel-Crafts acylation;10%
1-(5-ethanesulfonylmethyl-[2]thienyl)-ethanone
98954-61-1

1-(5-ethanesulfonylmethyl-[2]thienyl)-ethanone

5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

Conditions
ConditionsYield
With potassium permanganate
N'-tetramethylethylenediamine

N'-tetramethylethylenediamine

2-methyl-2-(thiophen-2-yl)-[1,3]dioxolane
5916-12-1

2-methyl-2-(thiophen-2-yl)-[1,3]dioxolane

5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

Conditions
ConditionsYield
With hydrogenchloride; n-butyllithium; carbon dioxide In tetrahydrofuran; hexane
2-Acetylthiophene
88-15-3

2-Acetylthiophene

5-(α-methoxyimino)ethyl-2-thiophenecarboxylic acid
1379398-60-3

5-(α-methoxyimino)ethyl-2-thiophenecarboxylic acid

5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

2-Acetylthiophene
88-15-3

2-Acetylthiophene

5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium carbonate; acetic acid / methanol; water / 86 °C / pH 4 - 5
2: polyphosphoric acid / 100 °C
3: sodium hypochlorite / methanol / 10 - 70 °C
4: hydrogenchloride / water / 55 - 60 °C
View Scheme
Multi-step reaction with 4 steps
1: acetic acid; sodium carbonate / water; methanol / 3 h / pH 5 / Heating
2: zinc(II) chloride; hydrogenchloride / water; chloroform / 12 h / 100 °C
3: sodium hypochlorite; hydrogenchloride / water; methanol / 4 h / 70 °C
4: hydrogenchloride / water / 12 h / 65 °C
View Scheme
2-(α-methoxyimino)ethylthiophene
114773-97-6

2-(α-methoxyimino)ethylthiophene

5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: polyphosphoric acid / 100 °C
2: sodium hypochlorite / methanol / 10 - 70 °C
3: hydrogenchloride / water / 55 - 60 °C
View Scheme
Multi-step reaction with 3 steps
1: zinc(II) chloride; hydrogenchloride / water; chloroform / 12 h / 100 °C
2: sodium hypochlorite; hydrogenchloride / water; methanol / 4 h / 70 °C
3: hydrogenchloride / water / 12 h / 65 °C
View Scheme
2-acetyl-5-(α-methoxyimino)ethylthiophene
114774-08-2

2-acetyl-5-(α-methoxyimino)ethylthiophene

5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hypochlorite / methanol / 10 - 70 °C
2: hydrogenchloride / water / 55 - 60 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium hypochlorite; hydrogenchloride / water; methanol / 4 h / 70 °C
2: hydrogenchloride / water / 12 h / 65 °C
View Scheme
5-(α-methoxyimino)ethyl-2-thiophenecarboxylic acid

5-(α-methoxyimino)ethyl-2-thiophenecarboxylic acid

5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

Conditions
ConditionsYield
With hydrogenchloride In water at 55 - 60℃;
With hydrogenchloride In water at 65℃; for 12h;
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

diazomethyl-trimethyl-silane
18107-18-1

diazomethyl-trimethyl-silane

methyl 5-acetyl-2-thiophenecarboxylate
4101-81-9

methyl 5-acetyl-2-thiophenecarboxylate

Conditions
ConditionsYield
In methanol; toluene at 0 - 20℃;100%
With tetrafluoroboric acid In dichloromethane; water at 0℃; for 2h;11%
methanol
67-56-1

methanol

5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

methyl 5-acetyl-2-thiophenecarboxylate
4101-81-9

methyl 5-acetyl-2-thiophenecarboxylate

Conditions
ConditionsYield
With sulfuric acid Reflux;92.81%
With thionyl chloride In N,N-dimethyl-formamide for 5h; Reflux;
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

5-(3-dimethylaminoacryloyl)thiophene-2-carboxylic acid methyl ester
866523-73-1

5-(3-dimethylaminoacryloyl)thiophene-2-carboxylic acid methyl ester

Conditions
ConditionsYield
In toluene at 110℃; for 16h;91%
In N,N-dimethyl-formamide Reflux;80%
In toluene for 15h; Heating / reflux;
In toluene Reflux;
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

ethanol
64-17-5

ethanol

5-acetyl-thiophene-2-carboxylic acid ethyl ester
33148-82-2

5-acetyl-thiophene-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 3h; Reflux; Dean-Stark;91%
With sulfuric acid for 72h; Heating / reflux;84%
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

N-[2-amino-1-(3-amino-3-oxopropyl)-1H-benzimidazol-5-yl]-N-methylbenzamide
658700-12-0

N-[2-amino-1-(3-amino-3-oxopropyl)-1H-benzimidazol-5-yl]-N-methylbenzamide

C25H23N5O4S
1092486-13-9

C25H23N5O4S

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃;90%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 24h;
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

N,O-dimethylhydroxylamine*hydrochloride
6638-79-5

N,O-dimethylhydroxylamine*hydrochloride

5-Acetyl-N-methoxy-N-methylthiophene-2-carboxamide
844502-57-4

5-Acetyl-N-methoxy-N-methylthiophene-2-carboxamide

Conditions
ConditionsYield
With 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dimethyl amine at 25℃; for 16h;86%
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

methyl iodide
74-88-4

methyl iodide

methyl 5-acetyl-2-thiophenecarboxylate
4101-81-9

methyl 5-acetyl-2-thiophenecarboxylate

Conditions
ConditionsYield
With sodium carbonate In DMF (N,N-dimethyl-formamide) at 20℃;80%
With potassium carbonate In N,N-dimethyl-formamide at 23℃; for 72h;72%
With potassium carbonate In N,N-dimethyl-formamide at 23℃;72%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 60h;
With sodium carbonate In N,N-dimethyl-formamide at 20℃;
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

tert-butyl alcohol
75-65-0

tert-butyl alcohol

tert-butyl-5-acetylthiophene-2-carboxylate
844502-29-0

tert-butyl-5-acetylthiophene-2-carboxylate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dimethyl amine at 25℃; for 16h;72%
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

N-(2-(pyridin-2-yl)propan-2-yl)benzamide

N-(2-(pyridin-2-yl)propan-2-yl)benzamide

2-(5-acetylthiophen-2-yl)-N-(2-(pyridin-2-yl)propan-2-yl)benzamide

2-(5-acetylthiophen-2-yl)-N-(2-(pyridin-2-yl)propan-2-yl)benzamide

Conditions
ConditionsYield
With copper (I) acetate; lithium carbonate; silver nitrate In N,N-dimethyl-formamide at 100℃; for 24h; Inert atmosphere; Sealed tube;45%
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

(R)-1-phenyl-ethyl-amine
3886-69-9

(R)-1-phenyl-ethyl-amine

sodium ethyltrithiocarbonate
67715-76-8

sodium ethyltrithiocarbonate

ethyl 2-oxo-2-[5-((R)-1-phenylethylcarbamoyl)thiophen-2-yl]ethyl trithiocarbonate
1039454-46-0

ethyl 2-oxo-2-[5-((R)-1-phenylethylcarbamoyl)thiophen-2-yl]ethyl trithiocarbonate

Conditions
ConditionsYield
Stage #1: 5-acetylthiophene-2-carboxylic acid With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 0.75h;
Stage #2: (R)-1-phenyl-ethyl-amine In tetrahydrofuran at 20℃; for 18h;
Stage #3: sodium ethyltrithiocarbonate Further stages;
44%
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

sodium ethyltrithiocarbonate
67715-76-8

sodium ethyltrithiocarbonate

aniline
62-53-3

aniline

ethyl 2-oxo-2-(5-phenylcarbamoylthiophen-2-yl)ethyl trithiocarbonate
1039454-48-2

ethyl 2-oxo-2-(5-phenylcarbamoylthiophen-2-yl)ethyl trithiocarbonate

Conditions
ConditionsYield
Stage #1: 5-acetylthiophene-2-carboxylic acid With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 0.75h;
Stage #2: aniline In tetrahydrofuran at 20℃; for 18h;
Stage #3: sodium ethyltrithiocarbonate Further stages;
22%
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

3,5-dimethylbenzyl amine
78710-55-1

3,5-dimethylbenzyl amine

sodium ethyltrithiocarbonate
67715-76-8

sodium ethyltrithiocarbonate

2-[5-(3,5-dimethylbenzylcarbamoyl)thiophen-2-yl]-2-oxoethyl ethyl trithiocarbonate
1039454-47-1

2-[5-(3,5-dimethylbenzylcarbamoyl)thiophen-2-yl]-2-oxoethyl ethyl trithiocarbonate

Conditions
ConditionsYield
Stage #1: 5-acetylthiophene-2-carboxylic acid With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 0.75h;
Stage #2: 3,5-dimethylbenzyl amine In tetrahydrofuran at 20℃; for 18h;
Stage #3: sodium ethyltrithiocarbonate Further stages;
21%
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

2-hydrazino-1,3-thiazole
30216-51-4

2-hydrazino-1,3-thiazole

5-[1-(Thiazol-2-yl-hydrazono)-ethyl]-thiophene-2-carboxylic acid
109793-48-8

5-[1-(Thiazol-2-yl-hydrazono)-ethyl]-thiophene-2-carboxylic acid

Conditions
ConditionsYield
In ethanol at 95℃; for 0.166667h;20%
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

sodium ethyltrithiocarbonate
67715-76-8

sodium ethyltrithiocarbonate

benzylamine
100-46-9

benzylamine

2-(5-benzylcarbamoylthiophen-2-yl)-2-oxoethyl ethyl trithiocarbonate
1039454-42-6

2-(5-benzylcarbamoylthiophen-2-yl)-2-oxoethyl ethyl trithiocarbonate

Conditions
ConditionsYield
Stage #1: 5-acetylthiophene-2-carboxylic acid With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 0.75h;
Stage #2: benzylamine In tetrahydrofuran at 20℃; for 18h;
Stage #3: sodium ethyltrithiocarbonate Further stages;
12%
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

(S)-1-phenyl-ethylamine
2627-86-3

(S)-1-phenyl-ethylamine

sodium ethyltrithiocarbonate
67715-76-8

sodium ethyltrithiocarbonate

ethyl 2-oxo-2-[5-((S)-1-phenylethylcarbamoyl)thiophen-2-yl]ethyl trithiocarbonate
1039454-44-8

ethyl 2-oxo-2-[5-((S)-1-phenylethylcarbamoyl)thiophen-2-yl]ethyl trithiocarbonate

Conditions
ConditionsYield
Stage #1: 5-acetylthiophene-2-carboxylic acid With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 0.75h;
Stage #2: (S)-1-phenyl-ethylamine In tetrahydrofuran at 20℃; for 18h;
Stage #3: sodium ethyltrithiocarbonate Further stages;
6%
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

5-ethyl-2-thiophenecarboxylic acid
23229-72-3

5-ethyl-2-thiophenecarboxylic acid

Conditions
ConditionsYield
With hydrazine hydrate; ethylene glycol at 145℃; Erhitzen des Reaktionsgemisches mit Kaliumhydroxid bis auf 193grad;
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

5-(1-hydroxyimino-ethyl)-thiophene-2-carboxylic acid
98279-55-1

5-(1-hydroxyimino-ethyl)-thiophene-2-carboxylic acid

Conditions
ConditionsYield
With potassium hydroxide; ethanol; hydroxylamine hydrochloride
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

diazodiphenylmethane
908093-98-1

diazodiphenylmethane

5-Acetyl-thiophene-2-carboxylic acid benzhydryl ester

5-Acetyl-thiophene-2-carboxylic acid benzhydryl ester

Conditions
ConditionsYield
In methanol at 25℃; Rate constant;
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

5-(2-Bromo-acetyl)-thiophene-2-carboxylic acid
96543-76-9

5-(2-Bromo-acetyl)-thiophene-2-carboxylic acid

Conditions
ConditionsYield
With bromine In acetic acid at 110℃; for 0.166667h;
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

[4-(5-amino-thiophen-2-yl)-pyrimidin-2-yl]-methyl-amine
866523-80-0

[4-(5-amino-thiophen-2-yl)-pyrimidin-2-yl]-methyl-amine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 91 percent / toluene / 16 h / 110 °C
2: NaOEt / 40 h / 70 °C
3: 87 percent / hydrazine / methanol / 16 h / 70 °C
4: 91 percent / aq. HCl; NaNO2 / acetic acid / 0.5 h / 0 °C
5: 30 percent / aq. HCl / 16 h / 100 °C
View Scheme
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

[4-(5-isocyanato-thiophen-2-yl)-pyrimidin-2-yl]-methyl-amine

[4-(5-isocyanato-thiophen-2-yl)-pyrimidin-2-yl]-methyl-amine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 91 percent / toluene / 16 h / 110 °C
2: NaOEt / 40 h / 70 °C
3: 87 percent / hydrazine / methanol / 16 h / 70 °C
4: 91 percent / aq. HCl; NaNO2 / acetic acid / 0.5 h / 0 °C
5: xylene / 0.42 h / 120 °C
View Scheme
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

5-(2-methylsulfanyl-pyrimidin-4-yl)-thiophene-2-carboxylic acid methyl ester
908834-77-5

5-(2-methylsulfanyl-pyrimidin-4-yl)-thiophene-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 91 percent / toluene / 16 h / 110 °C
2: 69 percent / pyridine / H2O / 68 h / 100 °C
View Scheme
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

5-(2-amino-pyrimidin-4-yl)-thiophene-2-carboxylic acid ethyl ester

5-(2-amino-pyrimidin-4-yl)-thiophene-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 91 percent / toluene / 16 h / 110 °C
2: NaOEt / 40 h / 70 °C
View Scheme
5-acetylthiophene-2-carboxylic acid
4066-41-5

5-acetylthiophene-2-carboxylic acid

5-(2-methylamino-pyrimidin-4-yl)-thiophene-2-carboxylic acid ethyl ester
866523-74-2

5-(2-methylamino-pyrimidin-4-yl)-thiophene-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 91 percent / toluene / 16 h / 110 °C
2: NaOEt / 40 h / 70 °C
View Scheme

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