Product Description Product Name 4-Bromomethyl-1,2-dihydroquinoline-2-one CAS No. 4876-10-2 Appearance White powder
Cas:4876-10-2
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inquiryWe are one of the sub-factories of NINGJIANG GROUP PHARMACEUTICAL AND CHEMICAL CORPORATION. Process Capability : WE HAVE ONE RESEARCH & DEVELOPMENT INSTITUTE. OUR COMPANY HAS THE ABILITY TO TEST THE QUALITY BY MEANS OF HPLC TESTING SYS
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inquiryDayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:4876-10-2
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:4876-10-2
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inquiryUnique advantages of 4-Bromomethyl-1,2-dihydroquinoline-2-one Cas 4876-10-2 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White powder Storage:cool dry place Package:25kg/drum App
Cas:4876-10-2
Min.Order:25 Kilogram
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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Cas:4876-10-2
Min.Order:100 Gram
FOB Price: $1300.0 / 2000.0
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inquiry
Cas:4876-10-2
Min.Order:1 Metric Ton
FOB Price: $1.0
Type:Manufacturers
inquiryTIANFUCHEM--4876-10-2--4-Bromomethyl-1,2-dihydroquinoline-2-one factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established
Cas:4876-10-2
Min.Order:1 Metric Ton
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inquiryAbout Product Details
Cas:4876-10-2
Min.Order:1 Kilogram
FOB Price: $1.0 / 5.0
Type:Lab/Research institutions
inquiryProduct name: 4-Bromomethyl-1, 2-dihydroquinoline-2-one Cas #: 4876-10-2 Molecular formula: C10H8BrNO Molecular weight: 238.08 EINECS #: 679-473-6 Item First grade
Cas:4876-10-2
Min.Order:1 Kilogram
FOB Price: $20.0 / 80.0
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:4876-10-2
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inquiryAdvantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s
Cas:4876-10-2
Min.Order:10 Gram
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inquiryHangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research, development and manufac
Cas:4876-10-2
Min.Order:1 Gram
FOB Price: $1.0 / 2.0
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Cas:4876-10-2
Min.Order:1 Gram
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inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:4876-10-2
Min.Order:1 Kilogram
FOB Price: $86.0 / 98.0
Type:Trading Company
inquiry4-Bromomethyl-1,2-dihydroquinoline-2-one CAS:4876-10-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high
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Min.Order:1 Gram
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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Min.Order:1 Kilogram
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Cas:4876-10-2
Min.Order:1 Gram
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Type:Trading Company
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Min.Order:10 Kilogram
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Cas:4876-10-2
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:4876-10-2
Min.Order:0 Metric Ton
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inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:4876-10-2
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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Cas:4876-10-2
Min.Order:1 Gram
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Cas:4876-10-2
Min.Order:10 Gram
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inquiry4-Bromomethyl-1,2-dihydroquinoline-2-oneAppearance:Pls see the Details Storage:Keep away of light, hot, water, Store in dry, dark and ventilated place Package:according to customers' requirements Application:Steroids, Cosmetics Ingredients, APIs, Int
Cas:4876-10-2
Min.Order:1 Gram
Negotiable
Type:Other
inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
Cas:4876-10-2
Min.Order:100 Gram
FOB Price: $100.0 / 2000.0
Type:Lab/Research institutions
inquiryConditions | Yield |
---|---|
With phosphorus pentoxide at 83℃; for 13h; Solvent; Flow reactor; Large scale; | 95.08% |
With sulfuric acid at 40℃; for 1.5h; | 64% |
With sulfuric acid Heating; |
Conditions | Yield |
---|---|
With sulfuric acid; bromine In chloroform | |
Multi-step reaction with 2 steps 1: bromine; acetic acid 2: sulfuric acid / 4 h View Scheme | |
Multi-step reaction with 2 steps 1: bromine / chloroform 2: sulfuric acid / 4 h / 90 °C View Scheme | |
Multi-step reaction with 2 steps 1: bromine / chloroform / 2 h / Heating / reflux 2: sulfuric acid / 1.5 h / 40 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: pyridine / xylene / 0.5 h / Heating / reflux 1.2: 3.07 h / Heating / reflux 2.1: bromine / chloroform / 2 h / Heating / reflux 3.1: sulfuric acid / 1.5 h / 40 °C View Scheme |
4-bromomethyl-2(1H)-quinolinone
2-acetylaminomalonic acid diethyl ester
2-acetylamino-2-(ethoxycarbonyl)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propionic acid ethyl ester
Conditions | Yield |
---|---|
With sodium ethanolate; tetra-(n-butyl)ammonium iodide In ethanol at 60℃; for 8h; Reagent/catalyst; Temperature; | 98.44% |
With sodium In ethanol for 2h; | 69% |
With sodium hydroxide In water; dimethyl sulfoxide at 20 - 30℃; for 2h; Reagent/catalyst; Solvent; Large scale; |
4-bromomethyl-2(1H)-quinolinone
N-(pyridin-4-yl)furan-2-carboxamide
N-[(2-Oxo-1,2-dihydroquinolin-4-yl)methyl]-N-pyridin-4-yl-2-furamide
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide at 40℃; for 2h; | 95% |
4-bromomethyl-2(1H)-quinolinone
Conditions | Yield |
---|---|
With ammonia In isopropyl alcohol at 60℃; for 4h; | 95% |
Conditions | Yield |
---|---|
With tetraethylammonium perchlorate; triethylamine In ethanol; dimethyl sulfoxide at 20℃; for 4h; Electrolysis; Green chemistry; | 95% |
4-bromomethyl-2(1H)-quinolinone
allyl alcohol
4-[(allyloxy)methyl]quinol-2(1H)-one
Conditions | Yield |
---|---|
Stage #1: allyl alcohol With sodium hydride In tetrahydrofuran at 0℃; for 4h; Reflux; Stage #2: 4-bromomethyl-2(1H)-quinolinone In tetrahydrofuran at 0 - 20℃; for 6h; | 91% |
Conditions | Yield |
---|---|
With triethylamine In toluene at 70 - 80℃; for 5h; Solvent; Temperature; | 90% |
4-bromomethyl-2(1H)-quinolinone
2-(2-propynylsulfanyl)-1H-1,3-benzimidazole
Conditions | Yield |
---|---|
With sodium azide; copper(II) sulfate; sodium L-ascorbate In water; N,N-dimethyl-formamide at 20℃; for 12h; | 89% |
4-bromomethyl-2(1H)-quinolinone
1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid
Conditions | Yield |
---|---|
Stage #1: 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid With potassium carbonate In water; acetonitrile at 20℃; for 0.0833333h; Stage #2: 4-bromomethyl-2(1H)-quinolinone In water; acetonitrile at 20℃; for 25h; | 88.9% |
4-bromomethyl-2(1H)-quinolinone
Conditions | Yield |
---|---|
In ethanol at 20℃; for 4h; | 88% |
4-bromomethyl-2(1H)-quinolinone
diethyl (((4-chlorophenyl)carbonyl)amino)propanedioate
ethyl 2-(4-chlorobenzamido)-2-ethoxyoxo-3-[2-(1H)-quinolin-4-yl]propionate
Conditions | Yield |
---|---|
Stage #1: diethyl (((4-chlorophenyl)carbonyl)amino)propanedioate With sodium ethanolate; sodium In ethanol at 20℃; for 1.5h; Stage #2: 4-bromomethyl-2(1H)-quinolinone In ethanol at 20℃; | 88% |
4-bromomethyl-2(1H)-quinolinone
4-hydroxy-benzaldehyde
4-[(1,2-dihydro-2-oxoquinolin-4-yl)methoxy]-benzaldehyde
Conditions | Yield |
---|---|
With potassium carbonate In ethanol for 8h; Reflux; | 87% |
4-bromomethyl-2(1H)-quinolinone
3-methyl-2-buten-1-ol
4-{[(3-methyl-2-buten-1-yl)oxy]methyl}quinol-2(1H)-one
Conditions | Yield |
---|---|
Stage #1: 3-methyl-2-buten-1-ol In tetrahydrofuran at 0℃; for 4h; Reflux; Stage #2: 4-bromomethyl-2(1H)-quinolinone With tetra-(n-butyl)ammonium iodide In tetrahydrofuran at -78 - 20℃; for 2h; | 83% |
N'-benzylidene-2-hydroxybenzohydrazide
4-bromomethyl-2(1H)-quinolinone
2-(2-Oxo-1,2-dihydro-quinolin-4-ylmethoxy)-benzoic acid [1-phenyl-meth-(E)-ylidene]-hydrazide
Conditions | Yield |
---|---|
80% |
4-bromomethyl-2(1H)-quinolinone
Benzimidazol-2-thiol
4-(2'-S-benzimidazolyl)mercaptomethylcarbostyril
Conditions | Yield |
---|---|
With potassium hydroxide In ethanol for 6h; Heating; | 80% |
Conditions | Yield |
---|---|
With potassium carbonate In ethanol for 5h; Heating; | 80% |
(2-hydroxyphenyl)mercury chloride
4-bromomethyl-2(1H)-quinolinone
4-(2-chloromercury-phenoxymethyl)-azachromene-2-one
Conditions | Yield |
---|---|
With potassium carbonate In butanone under N2; mixt. of 4-bromomethyl-1-azacoumarin, o-(chloromercury)phenol,anhyd. K2CO3 and dry butanone heated under reflux for 20 h; cooling to room temp., concn., soln. poured onto crushed ice, recrystn. from warm acetic acid; elem. anal.; | 80% |
4,5-dimethyl-7-hydroxycoumarin
4-bromomethyl-2(1H)-quinolinone
4-[(4,5-dimethyl-2-oxo-2H-chromen-7-yloxy)methyl]quinolin-2(1H)-one
Conditions | Yield |
---|---|
With potassium carbonate In ethanol for 8h; Reflux; | 80% |
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 5h; | 80% |
7-hydroxy-4-methyl-chromen-2-one
4-bromomethyl-2(1H)-quinolinone
4-[(4-methyl-2-oxo-2H-chromen-7-yloxy)methyl]quinolin-2(1H)-one
Conditions | Yield |
---|---|
With potassium carbonate In ethanol for 8h; Reflux; | 78% |
(E)-4-bromo-3-methyl-3-buten-1-ol
4-bromomethyl-2(1H)-quinolinone
Conditions | Yield |
---|---|
Stage #1: (E)-4-bromo-3-methyl-3-buten-1-ol With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 2h; Inert atmosphere; Stage #2: 4-bromomethyl-2(1H)-quinolinone In tetrahydrofuran; mineral oil at 0 - 20℃; for 22h; Inert atmosphere; | 78% |
4-bromomethyl-2(1H)-quinolinone
vanillin
4-[(1,2-dihydro-2-oxoquinolin-4-yl)methoxy]-3-methoxybenzaldehyde
Conditions | Yield |
---|---|
With potassium carbonate In ethanol for 8h; Reflux; | 77% |
ciprofloxacin
4-bromomethyl-2(1H)-quinolinone
Conditions | Yield |
---|---|
Stage #1: ciprofloxacin With potassium carbonate In water; acetonitrile at 20℃; for 0.0833333h; Stage #2: 4-bromomethyl-2(1H)-quinolinone In water; acetonitrile at 20℃; for 25h; | 75.7% |
4-bromomethyl-2(1H)-quinolinone
4-(mercaptomethyl)quinolin-2(1H)-one
Conditions | Yield |
---|---|
With thiourea In diethyl ether; ethanol 1.) room temperature, 2 h, 2.) reflux, 4 h, 3.) room temperature, overnight; | 75% |
Stage #1: 4-bromomethyl-2(1H)-quinolinone With thiourea In ethanol Reflux; Inert atmosphere; Stage #2: With water; sodium hydroxide In ethanol Reflux; Inert atmosphere; | |
With thiourea In diethyl ether; ethanol at 20℃; for 6h; Reflux; | |
Multi-step reaction with 2 steps 1: acetone / 20 °C 2: sulfuric acid; ethanol / Reflux View Scheme |
Conditions | Yield |
---|---|
With dipotassium hydrogenphosphate; copper(l) iodide; 1,10-Phenanthroline In acetonitrile at 110℃; for 36h; Inert atmosphere; | 75% |
With copper(l) iodide; N,N,N',N'',N'''-pentamethyldiethylenetriamine In acetonitrile at 80℃; for 12h; Schlenk technique; Inert atmosphere; regioselective reaction; | 68% |
6-hydroxy-4-methyl-chromen-2-one
4-bromomethyl-2(1H)-quinolinone
4-[(4-methyl-2-oxo-2H-chromen-6-yloxy)methyl]quinolin-2(1H)-one
Conditions | Yield |
---|---|
With potassium carbonate In ethanol for 8h; Reflux; | 74% |
4-bromomethyl-2(1H)-quinolinone
3-hydroxy-2-methyl-1-propene
4-{[(2-methylallyl)oxy]methyl}quinolin-2(1H)-one
Conditions | Yield |
---|---|
Stage #1: 3-hydroxy-2-methyl-1-propene With sodium hydride In tetrahydrofuran at 0℃; for 4h; Reflux; Stage #2: 4-bromomethyl-2(1H)-quinolinone In tetrahydrofuran at 0 - 20℃; for 6h; | 74% |
4-Fluorophenol
4-bromomethyl-2(1H)-quinolinone
4-[4'-fluorophenoxymethyl]-1-aza-coumarin
Conditions | Yield |
---|---|
With potassium carbonate for 10h; Reflux; | 70% |
4-bromomethyl-2(1H)-quinolinone
4-(azidomethyl)quinolin-2(1H)-one
Conditions | Yield |
---|---|
With sodium azide In water; acetone at 20℃; | 70% |
With sodium azide In water; N,N-dimethyl-formamide for 8h; | |
With sodium azide In water; acetone at 20℃; for 0.25h; | |
With sodium azide In water; N,N-dimethyl-formamide; acetone for 10h; |
4-bromomethyl-2(1H)-quinolinone
4-fluoroaniline
4-[4'-fluoroanilinomethyl]-1-aza-coumarin
Conditions | Yield |
---|---|
In 5,5-dimethyl-1,3-cyclohexadiene at 135 - 148℃; for 10h; | 68% |
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