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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Acetaminomalonic acid diethyl ester

Cas:1068-90-2

Min.Order:100 Gram

Negotiable

Type:Other

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Diethyl Acetamidomalonate supplier in China

Cas:1068-90-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------

High purity 1068-90-2 Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

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Jinan Finer Chemical Co., Ltd

Product description: Product name Diethyl acetamidomalonate CAS number 1068-90-2 Assay ≥99% Appearance White crystalline powder Capacity 500mt/year Application Pharmaceutical

Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:100 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

Diethyl acetamidomalonate manufacturer/supplier

Cas:1068-90-2

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Hangzhou Think Chemical Co. Ltd

Diethyl acetamidomalonate CAS NO.:1068-90-2 HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing &amp

High purity Diethyl acetamidomalonate CAS NO.:1068-90-2 supplier from china

Cas:1068-90-2

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off white powder Storage:Sealed, dry, microtherm , avoid light and smell Package:According to the demand of customer Application:Pharmaceutical intermediates Transportation:by air or by sea Port:shanghai

Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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EAST CHEMSOURCES LIMITED

Diethyl acetylaminomalonate Structural formula: CAS NO.: 1068-90-2 EINEC RN.: 213-952-9 Molecular Formula: C9H15NO5 Molecular Weight: 217

Acetamidomalonic acid diethyl ester

Cas:1068-90-2

Min.Order:1 Kilogram

FOB Price: $2.0 / 3.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Diethyl acetamidomalonate 1068-90-2 ISO Producer

Cas:1068-90-2

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

Diethyl acetamidomalonate 1068-90-2 /manufacturer/low price/high quality/in stock

Cas:1068-90-2

Min.Order:1 Gram

FOB Price: $13.0 / 15.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Diethyl acetamidomalonate -- CHemwill

Cas:1068-90-2

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

Diethyl Acetamidomalonate

Cas:1068-90-2

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc. We are specialized in chemical synthesis, process development of pharmaceu

Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

GMP Manufacturer CAS 1068-90-2 with best quality

Cas:1068-90-2

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Trading Company

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Leader Biochemical Group

About Product Details

China Biggest factory Supply High Quality Diethyl acetamidomalonate CAS 1068-90-2

Cas:1068-90-2

Min.Order:1 Kilogram

FOB Price: $3.0 / 5.0

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

Name Diethyl acetamidomalonate Synonyms Acetamidomalonic acid diethyl ester CAS NO. 1068-90-2 Molecular Formula C9H15NO5 Mo

Diethyl acetamidomalonate CAS: 1068-90-2

Cas:1068-90-2

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:White to light yellow powder Storage:room temperature Package:25kg/drum Application:Diethyl 2-Acetamidomalonate, is a versatile building block used for the synthesis of various pharmaceutical and biologically active compounds. It is an i

Diethyl acetamidomalonate factory price

Cas:1068-90-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

high quality 1068-90-2 Diethyl acetamidomalonate with best price

Cas:1068-90-2

Min.Order:10 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Diethyl acetamidomalonate 1068-90-2

Cas:1068-90-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research, development and manufac

Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:1 Kilogram

FOB Price: $68.0 / 75.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Beluga chemical professional supply High quality Diethyl acetamidomalonate CAS 1068-90-2 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Made

High quality Diethyl acetamidomalonate CAS 1068-90-2

Cas:1068-90-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

Diethyl Acetamidomalonate CAS NO.1068-90-2

Cas:1068-90-2

Min.Order:10 Gram

Negotiable

Type:Trading Company

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Triumph International Development Limilted

Appearance:white powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/Air/Courie

Diethyl acetamidomalonate

Cas:1068-90-2

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

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Synthetic route

diethyl aminomalonate hydrochloride
13433-00-6

diethyl aminomalonate hydrochloride

acetic anhydride
108-24-7

acetic anhydride

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;100%
With triethylamine In dichloromethane at 0 - 20℃;99%
diethyl 2-aminopropanedioate hydrochloride

diethyl 2-aminopropanedioate hydrochloride

acetic anhydride
108-24-7

acetic anhydride

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;100%
diethyl aminomalonate hydrochloride
13433-00-6

diethyl aminomalonate hydrochloride

acetyl chloride
75-36-5

acetyl chloride

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;96%
With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere;96%
diethyl 2-aminopropanedioate hydrochloride

diethyl 2-aminopropanedioate hydrochloride

acetyl chloride
75-36-5

acetyl chloride

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;96%
acetamide
60-35-5

acetamide

diethyl malonate
105-53-3

diethyl malonate

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With 2,2′-biquinoline-4,4'-dicarboxylic acid disodium salt; acetic acid; copper(l) chloride at 80 - 110℃; for 8h;93%
diethyl oximinomalonate
6829-41-0

diethyl oximinomalonate

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With zinc In water90%
Multi-step reaction with 2 steps
1: H2 / 10percent Pd/C / ethanol / 20520 Torr
2: ethanol
View Scheme
Multi-step reaction with 2 steps
1: palladium coal; ethanol / 2280 - 3040 Torr / Hydrogenation
2: ethanol
View Scheme
acetic acid
64-19-7

acetic acid

diethyl malonate
105-53-3

diethyl malonate

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With sodium nitrite Addition; Isonitrosoylation; N-acetylation;87%
aminomalonic acid diethyl ester
6829-40-9

aminomalonic acid diethyl ester

Triethyl orthoacetate
78-39-7

Triethyl orthoacetate

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
for 2h; Reflux;87%
diethyl malonate
105-53-3

diethyl malonate

A

1,4-dioxane
123-91-1

1,4-dioxane

B

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With acetic acid; sodium nitrite In waterA n/a
B 86%
diethyl acetylmalonate
570-08-1

diethyl acetylmalonate

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With chloroform; tris-(2-chloro-ethyl)-amine; sulfuric acid
diethyl acetylmalonate
570-08-1

diethyl acetylmalonate

A

methylcarbamoyl-malonic acid diethyl ester
15129-21-2

methylcarbamoyl-malonic acid diethyl ester

B

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With hydrogen azide; chloroform; sulfuric acid
With sodium azide; chloroform; sulfuric acid
aminomalonic acid diethyl ester
6829-40-9

aminomalonic acid diethyl ester

acetic anhydride
108-24-7

acetic anhydride

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With ethanol
With pyridine
In ethanol Yield given;
With triethylamine In tetrahydrofuran at 23℃; for 1h;
diethyl oximinomalonate
6829-41-0

diethyl oximinomalonate

acetic anhydride
108-24-7

acetic anhydride

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With nickel
With acetic acid; zinc
diethyl nitromalonate
603-67-8

diethyl nitromalonate

acetic anhydride
108-24-7

acetic anhydride

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With nickel Hydrogenation;
With palladium on activated charcoal at 60℃; under 58840.6 Torr; Hydrogenation;
acetic anhydride
108-24-7

acetic anhydride

α-Benzolazo-malonsaeure-diethylester
13636-61-8

α-Benzolazo-malonsaeure-diethylester

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With acetic acid; zinc
(1-ethoxy-ethylidenamino)-malonic acid diethyl ester

(1-ethoxy-ethylidenamino)-malonic acid diethyl ester

acetic acid
64-19-7

acetic acid

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
beim Kochen der Kalium-Verbindung;
aminomalonic acid diethyl ester
6829-40-9

aminomalonic acid diethyl ester

acetyl chloride
75-36-5

acetyl chloride

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With pyridine
With sodium carbonate In dichloromethane; water for 2h; Acetylation;
With benzothiazole-2-sulphonic acid In diethyl ether at 0 - 25℃; for 1h;
methanol
67-56-1

methanol

ethene
74-85-1

ethene

carbon monoxide
201230-82-2

carbon monoxide

sodium diethyl (acetylamino)malonate
30412-43-2

sodium diethyl (acetylamino)malonate

A

1-acetamidopropanetricarboxylic acid 1,1-diethyl-3-methyl ester
74090-40-7

1-acetamidopropanetricarboxylic acid 1,1-diethyl-3-methyl ester

B

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
Yield given. Multistep reaction. Yields of byproduct given;
acetylamino-bromomethyl-malonic acid diethyl ester
91011-83-5

acetylamino-bromomethyl-malonic acid diethyl ester

A

diethyl 2-acetylaminobutanedioate
1069-38-1

diethyl 2-acetylaminobutanedioate

B

diethyl α-acetamido, α-methylmalonate
55166-91-1

diethyl α-acetamido, α-methylmalonate

C

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
carbon-skeleton rearrangement mediated by hydrophobic Vitamin B12 covalent bound to a lipid species in a bilayer membrane; 1.) NaBH4, complex 1, 2.) N,N-bis(hexadecyl)-Nα-(6-sulfohexanoyl)-L-alaninamide, irradiation; other medium for irradiation;A 2 % Chromat.
B 57 % Chromat.
C 25 % Chromat.
acetylhydroxyimino-malonic acid diethyl ester

acetylhydroxyimino-malonic acid diethyl ester

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With diethyl ether; aluminium amalgam
acetyl chloride
75-36-5

acetyl chloride

sodium compound of aminomalonic acid diethyl ester

sodium compound of aminomalonic acid diethyl ester

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
With pyridine
acetoxyimino-malonic acid diethyl ester
90713-04-5

acetoxyimino-malonic acid diethyl ester

amalgamated aluminium

amalgamated aluminium

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
Reduktion;
diethyl malonate
105-53-3

diethyl malonate

Me3SiCH2C(Me)=CH(CH2)2CH(Me)-X

Me3SiCH2C(Me)=CH(CH2)2CH(Me)-X

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: NaH / tetrahydrofuran / 0.25 h / 23 °C
1.2: O-(4-nitrobenzoyl)-hydroxylamine / tetrahydrofuran / 23 °C
2.1: Et3N / tetrahydrofuran / 1 h / 23 °C
View Scheme
ethylesters of amino malonic acid
91469-69-1

ethylesters of amino malonic acid

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogenchloride / water / 5 h / Reflux
2: 2 h / Reflux
View Scheme
benzyl chloride
100-44-7

benzyl chloride

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

2-(N-acetylamino)-2-benzylpropanedioic diethyl ester
3235-26-5

2-(N-acetylamino)-2-benzylpropanedioic diethyl ester

Conditions
ConditionsYield
With 18-crown-6 ether; potassium carbonate In dichloromethane at 100 - 110℃; for 0.8h; Product distribution; var. solvents, var. time, other reaction partners;100%
With 18-crown-6 ether; potassium carbonate In N,N-dimethyl-formamide at 100 - 110℃; for 0.8h;100%
With ethanol; sodium ethanolate
With ethanol; sodium ethanolate
allyl bromide
106-95-6

allyl bromide

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

ethyl 2-acetamido-2-(ethoxycarbonyl)-4-pentenoate
14109-62-7

ethyl 2-acetamido-2-(ethoxycarbonyl)-4-pentenoate

Conditions
ConditionsYield
Stage #1: 2-acetylaminomalonic acid diethyl ester With sodium ethanolate In ethanol for 5h; Reflux;
Stage #2: allyl bromide In ethanol for 15h; Reflux;
100%
With caesium carbonate In acetonitrile Heating;99%
With ethanol; sodium97%
propargyl bromide
106-96-7

propargyl bromide

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

diethyl α-acetamido-α-propargylmalonate
61172-60-9

diethyl α-acetamido-α-propargylmalonate

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 20℃; for 18h;100%
With caesium carbonate In acetonitrile at 20℃; for 18h;99%
With sodium hydride In N,N-dimethyl-formamide at 60℃; for 3h;95%
methyl chloroacetate
96-34-4

methyl chloroacetate

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

2-Acetylamino-2-ethoxycarbonyl-succinic acid 1-ethyl ester 4-methyl ester

2-Acetylamino-2-ethoxycarbonyl-succinic acid 1-ethyl ester 4-methyl ester

Conditions
ConditionsYield
With 18-crown-6 ether; potassium carbonate In N,N-dimethyl-formamide at 100 - 110℃; for 0.5h;100%
diethyl 2-bromoethylphosphonate
5324-30-1

diethyl 2-bromoethylphosphonate

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

(N-acetylamino-3 bis-ethoxycarbonyl-3,3)-propylphosphonate de diethyle
107257-47-6

(N-acetylamino-3 bis-ethoxycarbonyl-3,3)-propylphosphonate de diethyle

Conditions
ConditionsYield
With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In acetonitrile for 8h; Heating;100%
With sodium hydride In toluene at 110℃; for 24h;100%
With sodium hydride; Diethyl carbonate In hexane; toluene; mineral oil at 110℃; for 24h;33.3 g
bis(2-chloroethyl) 2-chloroethylphosphonate
6294-34-4

bis(2-chloroethyl) 2-chloroethylphosphonate

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

(N-acetylamino-3 bis-ethoxycarbonyl-3,3)-propylphosphonate de di(chloro-2 ethyle)

(N-acetylamino-3 bis-ethoxycarbonyl-3,3)-propylphosphonate de di(chloro-2 ethyle)

Conditions
ConditionsYield
With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In acetonitrile for 8h; Heating;100%
4-bromo-1-(bromomethyl)-2-nitrobenzene
82420-34-6

4-bromo-1-(bromomethyl)-2-nitrobenzene

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

Ethyl 2-Acetamido-2-(4'-bromo-2'-nitrobenzyl)malonate
82420-36-8

Ethyl 2-Acetamido-2-(4'-bromo-2'-nitrobenzyl)malonate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide100%
Stage #1: 2-acetylaminomalonic acid diethyl ester With sodium ethanolate In ethanol at 20℃; for 0.5h;
Stage #2: 4-bromo-1-(bromomethyl)-2-nitrobenzene In ethanol
74%
68%
4-(bromomethyl)-1-fluoro-2-nitrobenzene
15017-52-4

4-(bromomethyl)-1-fluoro-2-nitrobenzene

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

ethyl 2-(acetylamino)-2-(ethoxycarbonyl)-3-(4'-fluoro-3'-nitrophenyl)propanoate
20367-99-1

ethyl 2-(acetylamino)-2-(ethoxycarbonyl)-3-(4'-fluoro-3'-nitrophenyl)propanoate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide for 4h; Ambient temperature;100%
With sodium hydride In N,N-dimethyl-formamide; mineral oil; pentane at 20℃; for 4h;100%
Stage #1: 2-acetylaminomalonic acid diethyl ester With sodium hydride In tetrahydrofuran; mineral oil for 3h; Reflux;
Stage #2: 4-(bromomethyl)-1-fluoro-2-nitrobenzene In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil Reflux;
100%
Stage #1: 2-acetylaminomalonic acid diethyl ester With sodium hydride In N,N-dimethyl-formamide; mineral oil
Stage #2: 4-(bromomethyl)-1-fluoro-2-nitrobenzene In N,N-dimethyl-formamide; mineral oil at 20℃; for 24h;
74%
With sodium hydride In hexanes; N,N-dimethyl-formamide; mineral oil at 20℃; for 4h;
2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

6'-(bromomethyl)-3',4'-dihydro-4,4-dimethyl-7'-nitrospiro(cyclohexane-1,1'(2H)-naphthalene)
205386-16-9

6'-(bromomethyl)-3',4'-dihydro-4,4-dimethyl-7'-nitrospiro(cyclohexane-1,1'(2H)-naphthalene)

C27H38N2O7
205386-17-0

C27H38N2O7

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide for 2.5h; Ambient temperature;100%
2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

(4-methoxyphenyl)methyl methyl carbonate
270921-39-6

(4-methoxyphenyl)methyl methyl carbonate

2-acetylamino-2-(4-methoxybenzyl)malonic acid diethyl ester
53612-87-6

2-acetylamino-2-(4-methoxybenzyl)malonic acid diethyl ester

Conditions
ConditionsYield
With 1,1'-bis-(diphenylphosphino)ferrocene; N,O-bis-(trimethylsilyl)-acetamide; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; potassium acetate In tetrahydrofuran at 80℃; for 24h;100%
With 1,1'-bis(diisopropylphosphino)ferrocene; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; caesium carbonate In N,N-dimethyl-formamide at 30℃; for 72h; Inert atmosphere;95%
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃;92%
2-isopropyl-4-chloromethylthiazole
40516-57-2

2-isopropyl-4-chloromethylthiazole

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

diethyl 2-acetamido-2-((2-isopropylthiazol-4-yl)methyl)malonate
1187649-36-0

diethyl 2-acetamido-2-((2-isopropylthiazol-4-yl)methyl)malonate

Conditions
ConditionsYield
Stage #1: 2-acetylaminomalonic acid diethyl ester With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃;
Stage #2: 2-isopropyl-4-chloromethylthiazole In N,N-dimethyl-formamide at 20℃;
100%
formaldehyd
50-00-0

formaldehyd

benzyl-methyl-amine
103-67-3

benzyl-methyl-amine

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

C18H26N2O5

C18H26N2O5

Conditions
ConditionsYield
In water at 20℃; for 4h;100%
3-(Dimethylaminomethyl)indole
87-52-5

3-(Dimethylaminomethyl)indole

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

acetylamino-indol-3-ylmethyl-malonic acid diethyl ester
5379-97-5

acetylamino-indol-3-ylmethyl-malonic acid diethyl ester

Conditions
ConditionsYield
With tributylphosphine In acetonitrile for 4h; Heating;99.5%
With sodium hydroxide; toluene
With sodium hydroxide; xylene
With sodium ethanolate; ethyl iodide
With ethanol; dimethyl sulfate
[1-(5-bromomethyl-isoxazol-3-yl)-3-methyl-butyl]-carbamic acid tert-butyl ester

[1-(5-bromomethyl-isoxazol-3-yl)-3-methyl-butyl]-carbamic acid tert-butyl ester

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

2-acetylamino-2-[3-(1-tert-butoxycarbonylamino-3-methyl-butyl)-isoxazol-5-ylmethyl]-malonic acid diethyl ester

2-acetylamino-2-[3-(1-tert-butoxycarbonylamino-3-methyl-butyl)-isoxazol-5-ylmethyl]-malonic acid diethyl ester

Conditions
ConditionsYield
With caesium carbonate99.4%
4-Fluorobenzyl bromide
459-46-1

4-Fluorobenzyl bromide

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

diethyl α-acetamido, α-(4-fluorobenzyl)malonate
380-71-2

diethyl α-acetamido, α-(4-fluorobenzyl)malonate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile Alkylation; Heating;99%
With potassium hydroxide; Aliquat 336 for 0.25h; Ambient temperature;71%
With caesium carbonate In acetonitrile at 130℃; Microwave irradiation;
propargyl p-toluenesulfonate
6165-76-0

propargyl p-toluenesulfonate

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

diethyl α-acetamido-α-propargylmalonate
61172-60-9

diethyl α-acetamido-α-propargylmalonate

Conditions
ConditionsYield
Stage #1: 2-acetylaminomalonic acid diethyl ester With potassium tert-butylate In 1,4-dioxane at 20 - 50℃; for 4h; Inert atmosphere;
Stage #2: propargyl p-toluenesulfonate In 1,4-dioxane at 50℃; Concentration; Solvent; Inert atmosphere; Reflux;
99%
{4-(bromomethyl)-2-[(2-nitrobenzyl)oxy]phenoxy}(tert-butyl)dimethylsilane

{4-(bromomethyl)-2-[(2-nitrobenzyl)oxy]phenoxy}(tert-butyl)dimethylsilane

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

diethyl 2-acetamido-2-{4-[(tert-butyldimethylsilyl)oxy]-3-[(2-nitrobenzyl)oxy]benzyl}malonate

diethyl 2-acetamido-2-{4-[(tert-butyldimethylsilyl)oxy]-3-[(2-nitrobenzyl)oxy]benzyl}malonate

Conditions
ConditionsYield
Stage #1: 2-acetylaminomalonic acid diethyl ester With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.333333h; Inert atmosphere;
Stage #2: {4-(bromomethyl)-2-[(2-nitrobenzyl)oxy]phenoxy}(tert-butyl)dimethylsilane In N,N-dimethyl-formamide; mineral oil at 20℃; for 4h; Inert atmosphere;
99%
4-bromomethyl-2(1H)-quinolinone
4876-10-2

4-bromomethyl-2(1H)-quinolinone

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

2-acetylamino-2-(ethoxycarbonyl)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propionic acid ethyl ester
4900-38-3

2-acetylamino-2-(ethoxycarbonyl)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propionic acid ethyl ester

Conditions
ConditionsYield
With sodium ethanolate; tetra-(n-butyl)ammonium iodide In ethanol at 60℃; for 8h; Reagent/catalyst; Temperature;98.44%
With sodium In ethanol for 2h;69%
With sodium hydroxide In water; dimethyl sulfoxide at 20 - 30℃; for 2h; Reagent/catalyst; Solvent; Large scale;
5-methoxygramine
16620-52-3

5-methoxygramine

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

acetylamino-(5-methoxy-indol-3-ylmethyl)-malonic acid diethyl ester
54744-69-3

acetylamino-(5-methoxy-indol-3-ylmethyl)-malonic acid diethyl ester

Conditions
ConditionsYield
With sodium hydroxide In toluene for 18h; Reflux;98%
With ethanol; sodium ethanolate; dimethyl sulfate
1-bromomethyl-3-nitrobenzene
3958-57-4

1-bromomethyl-3-nitrobenzene

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

diethyl 2-(acetylamino)-2-(3-nitrobenzyl)malonate
5432-19-9

diethyl 2-(acetylamino)-2-(3-nitrobenzyl)malonate

Conditions
ConditionsYield
Stage #1: 2-acetylaminomalonic acid diethyl ester With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.0833333h; Inert atmosphere;
Stage #2: 1-bromomethyl-3-nitrobenzene In N,N-dimethyl-formamide; mineral oil at 0℃; for 16h; Inert atmosphere;
98%
With ethanol; sodium ethanolate
2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

2-acetamido-3-ethoxy-3-oxopropanoic acid
54681-67-3, 187868-53-7

2-acetamido-3-ethoxy-3-oxopropanoic acid

Conditions
ConditionsYield
With sodium hydroxide; phosphate buffer; α-chymotrypsin for 5.25h; Product distribution; Ambient temperature; var. pH;98%
With sodium hydroxide In 1,4-dioxane; water at 20℃; for 17h;81%
With sodium hydroxide In 1,4-dioxane at 20℃; for 15h;76%
1-Bromo-3-phenylpropane
637-59-2

1-Bromo-3-phenylpropane

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

2-acetylamino-2-(3-phenyl-propyl)malonic acid diethyl ester
52161-73-6

2-acetylamino-2-(3-phenyl-propyl)malonic acid diethyl ester

Conditions
ConditionsYield
Stage #1: 2-acetylaminomalonic acid diethyl ester With sodium ethanolate In ethanol at 20℃; for 1.5h;
Stage #2: 1-Bromo-3-phenylpropane In ethanol for 16h; Heating;
98%
Stage #1: 2-acetylaminomalonic acid diethyl ester With sodium ethanolate In ethanol at 20℃; for 1.5h;
Stage #2: 1-Bromo-3-phenylpropane In ethanol for 16.25h; Heating / reflux;
98%
(i) Na, EtOH, (ii) /BRN= 2205527/; Multistep reaction;
With sodium ethanolate; sodium In ethanol; nitrogen
Stage #1: 2-acetylaminomalonic acid diethyl ester With sodium ethanolate In ethanol at 20℃; for 2h;
Stage #2: 1-Bromo-3-phenylpropane In ethanol at 20 - 73℃; for 28.25h;
benzyl bromide
100-39-0

benzyl bromide

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

2-(N-acetylamino)-2-benzylpropanedioic diethyl ester
3235-26-5

2-(N-acetylamino)-2-benzylpropanedioic diethyl ester

Conditions
ConditionsYield
With potassium carbonate In acetonitrile Alkylation; Heating;98%
With potassium hydroxide; Aliquat 336 for 0.25h; Ambient temperature;84%
With caesium carbonate In acetonitrile at 130℃; for 0.166667h; Microwave irradiation;82%
Stage #1: 2-acetylaminomalonic acid diethyl ester With sodium ethanolate In ethanol at 0℃; for 0.0833333h; Inert atmosphere;
Stage #2: benzyl bromide In ethanol for 2h; Inert atmosphere; Reflux;
With caesium carbonate In acetonitrile at 130℃; Microwave irradiation;
rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene
87751-69-7

rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

diethyl (R)-(acetylamino)[(E)-1,3-diphenylprop-2-en-1-yl]malonate

diethyl (R)-(acetylamino)[(E)-1,3-diphenylprop-2-en-1-yl]malonate

Conditions
ConditionsYield
With N,O-bis-(trimethylsilyl)-acetamide; potassium acetate; chiral (phosphinoaryldihydrooxazole)allyl-Pd(II) In dichloromethane at 23℃;98%
With bis(η3-allyl-μ-chloropalladium(II)); C2-symmetric chiral P; potassium acetate; bis-(trimethylsilyl)acetamide In dichloromethane for 0.5h; Ambient temperature;98%
4-(bromomethyl)-3-nitrobenzaldehyde
155526-65-1

4-(bromomethyl)-3-nitrobenzaldehyde

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

ethyl 2-(acetylamino)-2-(ethoxycarbonyl)-3-(4-formyl-2-nitrophenyl)propanoate
168965-43-3

ethyl 2-(acetylamino)-2-(ethoxycarbonyl)-3-(4-formyl-2-nitrophenyl)propanoate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide for 2.5h; Ambient temperature;98%
With sodium hydride In N,N-dimethyl-formamide
rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene
87751-69-7

rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

diethyl (S)-(acetylamino)[(E)-1,3-diphenylprop-2-en-1-yl]malonate

diethyl (S)-(acetylamino)[(E)-1,3-diphenylprop-2-en-1-yl]malonate

Conditions
ConditionsYield
With N,O-bis-(trimethylsilyl)-acetamide; bis(η3-allyl-μ-chloropalladium(II)); (S)-7-(diphenylphosphino)-2′-isopropyl-2,3-dihydro-5′H-spiro[indene-1,4′-oxazole]; potassium acetate In toluene at 0℃; for 5h; Inert atmosphere; Schlenk technique; enantioselective reaction;98%
With bis(η3-allyl-μ-chloropalladium(II)); potassium acetate; (1R,2R)-2-[N-(2-diphenylphosphanylbenzoyl)amino]cyclohexylcarbamic acid tert-butyl ester In diethyl ether at 25℃; for 6h; enantioselective reaction;98%
With benzenesulfonamide; potassium acetate; (1R,2S,4R,5S)-(+)-2,5-dimethyl-7-phenyl-7-phosphabicyclo[2.2.1]heptane; bis(η3-allyl-μ-chloropalladium(II)) In toluene for 2h;95%
With benzenesulfonamide; potassium acetate; (S,S)-N,N'-1,2-bis(S-cyclopentyl-S-phenyl-sulfonimidoyl)-ethane; bis(η3-allyl-μ-chloropalladium(II)) In dichloromethane at 45℃; for 96h;89%
2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

2-ethylsulfanyl-3-(ethylsulfanyl-trimethylsilanyl-methyl)-1H-indole
247222-86-2

2-ethylsulfanyl-3-(ethylsulfanyl-trimethylsilanyl-methyl)-1H-indole

2-acetylamino-2-(2-ethylsulfanyl-1H-indol-3-ylmethyl)-malonic acid diethyl ester

2-acetylamino-2-(2-ethylsulfanyl-1H-indol-3-ylmethyl)-malonic acid diethyl ester

Conditions
ConditionsYield
With tributylphosphine In acetonitrile at 80℃; for 9h; Alkylation;98%
methyl (naphthalen-1-ylmethyl) carbonate

methyl (naphthalen-1-ylmethyl) carbonate

2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

diethyl (N-acetylamino)[(1-naphthyl)methyl]malonate
5440-57-3

diethyl (N-acetylamino)[(1-naphthyl)methyl]malonate

Conditions
ConditionsYield
With 1,1'-bis-(diphenylphosphino)ferrocene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃; for 1h;98%
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