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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

4,5-Dimethoxy-2-nitrobenzoic acid Manufacturer/High quality/Best price/In stock

Cas:4998-07-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 6-Nitro Veratric Acid??????????? supplier in China

Cas:4998-07-6

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price. 1.Quick response within 24 hours; 2.Best quality in your requirement; 3.We pay more attention on delivery time, and usually ship on time; 4.Under the premise of safety and effectiveness, we can pr

CAS:4998-07-6/High quality/Factory supply

Cas:4998-07-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

4, 5-Dimethoxy-2-Nitrobenzoic Acid

Cas:4998-07-6

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

high quality and best price of 4,5-Dimethoxy-2-nitrobenzoic acid Henan Tianfu Chemical Co.,LTD was built in 2009 with an ISO certificate in the past 5 years, we have grown up as a famous fine chemicals supplier in china and we had established sta

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 4998-07-6 with best quality

Cas:4998-07-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Benzoic acid,4,5-dimethoxy-2-nitro-

Cas:4998-07-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

4,5-Dimethoxy-2-nitrobenzoic acid CAS: 4998-07-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

4,5-Dimethoxy-2-nitrobenzoic acid CAS: 4998-07-6

Cas:4998-07-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:4998-07-6

Cas:4998-07-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

6-Nitroveratric Acid

Cas:4998-07-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzoic acid,4,5-dimethoxy-2-nitro-

Cas:4998-07-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Send Pharmaceutical Technology Co., Ltd.

low price high quality high purity good sevice stock Appearance:white Storage:Preserve In Well-Closed, Light-Resistant and Tight Containers. Store In Cool & Dry Place Package:1g,5g,10g...1kg,5kg...more Application:Pharmaceutical intermediat

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

4,5-Dimethoxy-2-nitrobenzoicacid

Cas:4998-07-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Wuhan BJM Pharm Inc.

Wuhan BJM Pharm Inc. was found in 2013, located in Hubei Province, where has long history, rich culture, convenient traffic, beautiful environment and preferential policy. We have two factories in Dezhou, Shandong and Xianning, Hubei. The factor

cas:4998-07-6/ 4,5-Dimethoxy-2-nitrobenzoic acid Gefitinib intermediate

Cas:4998-07-6

Min.Order:1 Kilogram

FOB Price: $5.0 / 8.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermediate

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4,5-Dimethoxy-2-nitrobenzoic acid Cas no.4998-07-6 98%

Cas:4998-07-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

4,5-Dimethoxy-2-nitrobenzoic acid

Cas:4998-07-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

6-Nitroveratric acid

Cas:4998-07-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

1-(6-amino-2-bromo-3,4-dimethoxyphenyl)ethan-1-one

1-(6-amino-2-bromo-3,4-dimethoxyphenyl)ethan-1-one

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
Stage #1: 1-(6-amino-2-bromo-3,4-dimethoxyphenyl)ethan-1-one With 1 ,5-pentanediol for 0.666667h;
Stage #2: With nickel(III) oxide; potassium carbonate at 70℃; for 0.666667h; pH=9; Temperature; pH-value;
96%
2-nitroveratraldehyde
20357-25-9

2-nitroveratraldehyde

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
With sodium chlorite; dihydrogen peroxide; acetic acid In methanol; water at 50℃; Solvent; Temperature; Concentration; Reagent/catalyst;93%
Stage #1: 6-nitroveratraldehyde With potassium dihydrogenphosphate In water; acetonitrile
Stage #2: With sodium chlorite In water; acetonitrile at 25 - 35℃;
88%
With potassium permanganate; sodium hydroxide for 7h;83%
Veratric acid
93-07-2

Veratric acid

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
With nitric acid; acetic acid at 90℃; under 11251.1 Torr; for 0.0833333h; Temperature; Pressure; Flow reactor;87.6%
With nitric acid In water at 60℃; for 6h; Cooling with ice;77%
With nitric acid at 60℃; for 6.5h; Cooling with ice;77%
3-amino-4,5-dimethoxy-2-nitro-benzoic acid

3-amino-4,5-dimethoxy-2-nitro-benzoic acid

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

1-(4,5-dimethoxy-2-nitro-benzyl)-3,4-dihydro-isoquinoline

1-(4,5-dimethoxy-2-nitro-benzyl)-3,4-dihydro-isoquinoline

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
Oxydation;
Veratric acid
93-07-2

Veratric acid

A

3,4-dimethoxynitrobenzene
709-09-1

3,4-dimethoxynitrobenzene

B

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
With nitric acid
2-(4,5-dimethoxy-2-nitro-phenyl)-3,5,7-trimethoxy-chromen-4-one
861571-93-9

2-(4,5-dimethoxy-2-nitro-phenyl)-3,5,7-trimethoxy-chromen-4-one

permanganate solution

permanganate solution

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

2-(4,5-dimethoxy-2-nitro-phenyl)-3-hydroxy-7-methoxy-chroman-5,8-quinone

2-(4,5-dimethoxy-2-nitro-phenyl)-3-hydroxy-7-methoxy-chroman-5,8-quinone

potassium permanganate

potassium permanganate

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

nitric acid
7697-37-2

nitric acid

Veratric acid
93-07-2

Veratric acid

A

3,4-dimethoxynitrobenzene
709-09-1

3,4-dimethoxynitrobenzene

B

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

diazotized 6-nitro-5-amino-3.4-dimethoxy-benzoic acid

diazotized 6-nitro-5-amino-3.4-dimethoxy-benzoic acid

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
With ethanol
nitrocatechonetrimethyl ether

nitrocatechonetrimethyl ether

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
With potassium permanganate
nitropapaverine iodomethylate

nitropapaverine iodomethylate

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
With potassium permanganate; water
14-nitro-N-methylpapaverinium iodide
16620-92-1

14-nitro-N-methylpapaverinium iodide

aqueous potassium permanganate

aqueous potassium permanganate

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
at 100℃;
(4,5-dimethoxy-2-methyl-3-nitro-phenyl)-hydrazine
861363-56-6

(4,5-dimethoxy-2-methyl-3-nitro-phenyl)-hydrazine

copper(II) sulfate
7758-99-8

copper(II) sulfate

acetic acid
64-19-7

acetic acid

A

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

B

3,4-Dimethoxy-2-nitro-benzoic acid
79025-28-8

3,4-Dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
Oxydation des entstandenen Oels mit Permanganat;
methyl 4,5-dimethoxy-2-nitrobenzoate
26791-93-5

methyl 4,5-dimethoxy-2-nitrobenzoate

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran
With sodium hydroxide In methanol
Stage #1: methyl 4,5-dimethoxy-2-nitrobenzoate With potassium hydroxide; water at 0 - 70℃; Heating / reflux;
Stage #2: With acetic acid In water at 20℃; pH=6.6;
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: K2CO3 / acetone / Heating
2: HNO3; acetic acid / 50 - 60 °C
3: NaOH / tetrahydrofuran
View Scheme
3-methoxy-4-hydroxybenzoic acid
121-34-6

3-methoxy-4-hydroxybenzoic acid

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: H2SO4 / Heating
2: K2CO3 / acetone / Heating
3: HNO3; acetic acid / 50 - 60 °C
4: NaOH / tetrahydrofuran
View Scheme
methyl 3,4-dimethoxybenzoate
2150-38-1

methyl 3,4-dimethoxybenzoate

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HNO3; acetic acid / 50 - 60 °C
2: NaOH / tetrahydrofuran
View Scheme
vanillin
121-33-5

vanillin

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
3: KMnO4
View Scheme
3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: KMnO4
View Scheme
Multi-step reaction with 2 steps
1: nitric acid / 5 - 10 °C
2: KOH-solution; KMnO4
View Scheme
Multi-step reaction with 2 steps
1: nitric acid / 1 h / 20 - 25 °C
2: sodium hydroxide; potassium permanganate / 7 h
View Scheme
1,2-dimethoxy-4-(2-propenyl)benzene
93-15-2

1,2-dimethoxy-4-(2-propenyl)benzene

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: water; KMnO4 / 80 - 90 °C
2: nitric acid
View Scheme
(3,4-dimethoxyphenyl)methanol
93-03-8

(3,4-dimethoxyphenyl)methanol

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetic anhydride; nitric acid / 6 h / 0 - 20 °C
2: potassium permanganate; copper(ll) sulfate pentahydrate; potassium hydroxide / benzene / 10 h / Reflux
View Scheme
6-nitroveratryl alcohol
1016-58-6

6-nitroveratryl alcohol

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Conditions
ConditionsYield
With potassium permanganate; copper(ll) sulfate pentahydrate; potassium hydroxide In benzene for 10h; Reflux;13 g
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

4,5-dimethoxy-2-nitrobenzoyl chloride
29568-78-3

4,5-dimethoxy-2-nitrobenzoyl chloride

Conditions
ConditionsYield
With thionyl chloride In toluene for 3h; Heating;100%
With phosphorus pentachloride
With thionyl chloride; chloroform
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

2-(4-aminophenyl)-2-methylpropionitrile
115279-57-7

2-(4-aminophenyl)-2-methylpropionitrile

N-[4-(cyano-dimethyl-methyl)-phenyl]-4,5-dimethoxy-2-nitro-benzamide
1067193-04-7

N-[4-(cyano-dimethyl-methyl)-phenyl]-4,5-dimethoxy-2-nitro-benzamide

Conditions
ConditionsYield
Stage #1: 4,5-dimethoxy-2-nitro-benzoic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 1h;
Stage #2: 2-(4-aminophenyl)-2-methylpropionitrile With triethylamine In dichloromethane at 20℃;
100%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

3,4-dimethoxynitrobenzene
709-09-1

3,4-dimethoxynitrobenzene

Conditions
ConditionsYield
With silver carbonate In dimethyl sulfoxide at 120℃; for 16h;100%
With copper(l) iodide; triethylamine In dimethyl sulfoxide at 140℃; under 760.051 Torr; for 20h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; Schlenk technique;95%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

potassium 2-nitro-4,5-dimethoxybenzoate
1444018-10-3

potassium 2-nitro-4,5-dimethoxybenzoate

Conditions
ConditionsYield
With potassium tert-butylate In ethanol at 20℃; for 3h; Inert atmosphere;100%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

2-nitro-4-methoxy-5-hydroxybenzoic acid
31839-20-0

2-nitro-4-methoxy-5-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: 4,5-dimethoxy-2-nitro-benzoic acid With sodium hydroxide; water at 100℃; for 3h;
Stage #2: With hydrogenchloride In water at 0℃; pH=< 2;
99%
With water; sodium hydroxide at 100℃; for 3h; Inert atmosphere;99%
With water; sodium hydroxide at 100℃; for 6h;97.6%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

2-Amino-4,5-dimethoxybenzoic acid
5653-40-7

2-Amino-4,5-dimethoxybenzoic acid

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; under 7600.51 Torr; for 6h;97%
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; for 24h;92%
With hydrazine hydrate In ethanol at 60℃; for 5h; Sealed tube; Green chemistry; chemoselective reaction;87%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

2,2,2,-trichloroethoxycarbonyl azide

2,2,2,-trichloroethoxycarbonyl azide

2,2,2-trichloroethyl (4,5-dimethoxy-2-nitrophenyl)carbamate

2,2,2-trichloroethyl (4,5-dimethoxy-2-nitrophenyl)carbamate

Conditions
ConditionsYield
With dmap; copper diacetate In acetonitrile at 100℃; for 6h; Schlenk technique; Sealed tube; Inert atmosphere;94%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

N,N-dimethyl-4,5-dimethoxy-2-nitrobenzamide
349411-81-0

N,N-dimethyl-4,5-dimethoxy-2-nitrobenzamide

Conditions
ConditionsYield
With trichlorophosphate at 120℃; for 1h; Sealed tube;93%
With trichlorophosphate at 120℃; for 1h;93%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

4,5-dimethoxy-2-nitrobenzamide
4959-60-8

4,5-dimethoxy-2-nitrobenzamide

Conditions
ConditionsYield
Stage #1: 4,5-dimethoxy-2-nitro-benzoic acid With thionyl chloride for 0.833333h; Heating;
Stage #2: With ammonium hydroxide
88.5%
Stage #1: 4,5-dimethoxy-2-nitro-benzoic acid With triethylamine; Diphenylphosphinic chloride In chloroform
Stage #2: With ammonia
Multi-step reaction with 2 steps
1: SOCl2
2: NH4OH
View Scheme
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

α-bromoacetophenone
70-11-1

α-bromoacetophenone

4,5-dimethoxy-2-nitro-benzoic acid 2-oxo-2-phenyl-ethyl ester

4,5-dimethoxy-2-nitro-benzoic acid 2-oxo-2-phenyl-ethyl ester

Conditions
ConditionsYield
With triethylamine In acetone for 1.5h;86%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

tetraethylammonium hydroxide
77-98-5

tetraethylammonium hydroxide

tetraethylammonium 4,5-dimethoxy-2-nitrobenzoate

tetraethylammonium 4,5-dimethoxy-2-nitrobenzoate

Conditions
ConditionsYield
In methanol; water at 20℃;86%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

(2S,4R)-4-hydroxy-2-proline methyl ester 4-toluenesulfonate

(2S,4R)-4-hydroxy-2-proline methyl ester 4-toluenesulfonate

1-(4,5-dimethoxy-2-nitrobenzoyl)-4-hydroxypyrrolidine-2-carboxylic acid methyl ester
54431-30-0

1-(4,5-dimethoxy-2-nitrobenzoyl)-4-hydroxypyrrolidine-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Stage #1: 4,5-dimethoxy-2-nitro-benzoic acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 16h;
Stage #2: (2S,4R)-4-hydroxy-2-proline methyl ester 4-toluenesulfonate With triethylamine In dichloromethane at -20 - 20℃; for 16h;
85%
With oxalyl dichloride; TEA In dichloromethane; N,N-dimethyl-formamide at 20℃;57%
styrene
100-42-5

styrene

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

4,5-dimethoxy-2-nitrostilbene

4,5-dimethoxy-2-nitrostilbene

Conditions
ConditionsYield
With silver carbonate; palladium(II) trifluoroacetate In dimethyl sulfoxide; N,N-dimethyl-formamide at 120℃; for 3h; Heck olefination;85%
oxalyl dichloride
79-37-8

oxalyl dichloride

(2S)(4R)-N-[4-benzyloxy-5-methoxy-2-(2',2',2'-trichloroethoxy)carbonyl]-2-(tert-butyldimethylsilyloxymethyl) -4-hydroxypyrrolidine

(2S)(4R)-N-[4-benzyloxy-5-methoxy-2-(2',2',2'-trichloroethoxy)carbonyl]-2-(tert-butyldimethylsilyloxymethyl) -4-hydroxypyrrolidine

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

N-(4,5-dimethoxy-2-nitrobenzoyl)hydroxyproline Methyl Ester

N-(4,5-dimethoxy-2-nitrobenzoyl)hydroxyproline Methyl Ester

Conditions
ConditionsYield
With triethanolamine; N,N-dimethyl-formamide In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran85%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

Diphenyliodonium triflate
66003-76-7

Diphenyliodonium triflate

4,5-dimethoxy-2-nitrobiphenyl
92200-31-2

4,5-dimethoxy-2-nitrobiphenyl

Conditions
ConditionsYield
With silver carbonate; bis[2-(diphenylphosphino)phenyl] ether; palladium dichloride In dimethyl sulfoxide at 150℃; for 1h;85%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

1-chloro-4,5-dimethoxy-2-nitrobenzene
3899-65-8

1-chloro-4,5-dimethoxy-2-nitrobenzene

Conditions
ConditionsYield
With oxygen; silver carbonate; potassium hydroxide; copper dichloride In dimethyl sulfoxide; N,N-dimethyl-formamide at 130 - 140℃;85%
With copper(l) iodide; oxygen; copper(l) chloride In dimethyl sulfoxide at 160℃; under 760.051 Torr; for 30h; Schlenk technique; Sealed tube;65%
With 2.9-dimethyl-1,10-phenanthroline; oxygen; copper (I) acetate; silver sulfate; sodium chloride In dimethyl sulfoxide at 160℃; for 24h; Schlenk technique;52%
With 2.9-dimethyl-1,10-phenanthroline; oxygen; copper diacetate; silver sulfate; sodium chloride In dimethyl sulfoxide at 160℃; under 760.051 Torr; for 20h; Schlenk technique;52%
iodobenzene
591-50-4

iodobenzene

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

4,5-dimethoxy-2-nitrobiphenyl
92200-31-2

4,5-dimethoxy-2-nitrobiphenyl

Conditions
ConditionsYield
With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; N,N-dimethyl-aniline; silver carbonate; palladium dichloride at 150℃; for 2h;82%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

allyl alcohol
107-18-6

allyl alcohol

allyl 4,5-dimethoxy-2-nitrobenzoate

allyl 4,5-dimethoxy-2-nitrobenzoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; Steglich Esterification;82%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

3-hydroxy-2-methyl-1-propene
513-42-8

3-hydroxy-2-methyl-1-propene

2-methylallyl 4,5-dimethoxy-2-nitrobenzoate
1286732-04-4

2-methylallyl 4,5-dimethoxy-2-nitrobenzoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; Steglich Esterification;82%
2-bromobenzoic acid methyl ester
610-94-6

2-bromobenzoic acid methyl ester

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

2,3-dimethoxydibenzopyran-6-one
108012-00-6

2,3-dimethoxydibenzopyran-6-one

Conditions
ConditionsYield
With palladium(II) acetylacetonate; potassium carbonate; bis[2-(diphenylphosphino)phenyl] ether; copper(l) chloride In 1-methyl-pyrrolidin-2-one at 165℃; for 16h; Inert atmosphere; Molecular sieve; chemoselective reaction;81%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

dioctyltin(IV) oxide
870-08-6

dioctyltin(IV) oxide

n-Oct2Sn(4,5-dimethoxy-2-nitrobenzoate)2
1229818-23-8

n-Oct2Sn(4,5-dimethoxy-2-nitrobenzoate)2

Conditions
ConditionsYield
In toluene byproducts: H2O; Stoich. amounts of HL and n-Oct2SO were mixed in toluene, reflux for 6-7h, H2O was removed using a Dean-Stark apparatus; Toluene was evapd. under reduced pressure, mass was crystd. from CHCl3:acetone (1:1); elem. anal.;80%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

tributyltin chloride
1461-22-9

tributyltin chloride

n-Bu3Sn(4,5-dimethoxy-2-nitrobenzoate)
1229818-10-3

n-Bu3Sn(4,5-dimethoxy-2-nitrobenzoate)

Conditions
ConditionsYield
With Et3N In chloroform byproducts: Et3NHCl; Et3N (1 mmol) was added to dissolved in solvent HL (1 mmol), mixt. was refluxed 30 min, 1 mmol n-Bu3SnCl was added, solution was refluxed for 4-7 h, mixt. was kept at 25°C overnight; Et3NHCl was filtered off, solvent was evapd. under redused pressure, mass was crystd. from CHCL3:n-hexane (1:1); elem. anal;80%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

triphenyltin chloride
639-58-7

triphenyltin chloride

Ph3Sn(4,5-dimethoxy-2-nitrobenzoate)
1229818-12-5

Ph3Sn(4,5-dimethoxy-2-nitrobenzoate)

Conditions
ConditionsYield
With Et3N In chloroform byproducts: Et3NHCl; Et3N (1 mmol) was added to dissolved in solvent HL (1 mmol), mixt. was refluxed 30 min, 1 mmol n-Bu3SnCl was added, solution was refluxed for 4-7 h, mixt. was kept at 25°C overnight.; Et3NHCl was filtered off, solvent was evapd. under redused pressure, mass was crystd. from CHCl3:n-hexane (1:1); elem. anal;80%
4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

4,4',5,5'-tetramethoxy-2,2'-dinitro-1,1'-biphenyl
22296-40-8

4,4',5,5'-tetramethoxy-2,2'-dinitro-1,1'-biphenyl

Conditions
ConditionsYield
With triphenylphosphine; silver carbonate; palladium dichloride In dimethyl sulfoxide at 130℃; for 6h; Inert atmosphere;80%
(E)-p-methoxy-cinnamyl alcohol
53484-50-7

(E)-p-methoxy-cinnamyl alcohol

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

4-methoxycinnamyl 4,5-dimethoxy-2-nitrobenzoate
1620682-50-9

4-methoxycinnamyl 4,5-dimethoxy-2-nitrobenzoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; Steglich Esterification;80%
(2S,4R)-2-t-butyldimethylsilyloxymethyl-4-oxyacetylpyrrolidine
864755-03-3

(2S,4R)-2-t-butyldimethylsilyloxymethyl-4-oxyacetylpyrrolidine

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

(2S)(4R)-N-(4,5-dimethoxy-2-nitrobenzoyl)-2-(tert-butyldimethylsilyloxymethyl)-4-oxyacetylpyrrolidine
864755-12-4

(2S)(4R)-N-(4,5-dimethoxy-2-nitrobenzoyl)-2-(tert-butyldimethylsilyloxymethyl)-4-oxyacetylpyrrolidine

Conditions
ConditionsYield
Stage #1: 4,5-dimethoxy-2-nitro-benzoic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In DMF (N,N-dimethyl-formamide); dichloromethane at 0 - 20℃; for 1h;
Stage #2: (2S,4R)-2-t-butyldimethylsilyloxymethyl-4-oxyacetylpyrrolidine In dichloromethane at 20 - 55℃; for 18h;
79.9%
para-iodoanisole
696-62-8

para-iodoanisole

4,5-dimethoxy-2-nitro-benzoic acid
4998-07-6

4,5-dimethoxy-2-nitro-benzoic acid

4',4,5-trimethoxy-2-nitrobiphenyl

4',4,5-trimethoxy-2-nitrobiphenyl

Conditions
ConditionsYield
With triphenyl-arsane; silver carbonate; palladium dichloride In dimethyl sulfoxide at 150℃; for 6h;79%
With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; N,N-dimethyl-aniline; silver carbonate; palladium dichloride at 150℃; for 2h;72%

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