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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages of Flufenamic acid Cas 530-78-9 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White powder Storage:Cool dry place Package:25kg/drum Application:a

Hot selling Flufenamic acid Cas 530-78-9 with high quality and cheap price

Cas:530-78-9

Min.Order:1 Kilogram

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Type:Trading Company

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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production Cyromazine、lead diacetate trihydrate /Lead acetate trihydrateC、 2-phenylacetamide 、 4-Aminophenyl-1-phenethylpiperidine 、Citric acid monohydrate 、 Citric acid/c

530-78-9 Benzoic acid,2-[[3-(trifluoromethyl)phenyl]amino]-

Cas:530-78-9

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Flufenamic acid

Cas:530-78-9

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Flufenamic acid 530-78-9 GMP Manufacturer

Cas:530-78-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti

High purity Flufenamic acid 98% TOP1 supplier in China

Cas:530-78-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Flufenamic acid (base and/or unspecified salts)

Cas:530-78-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

Flufenamic acid

Cas:530-78-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 530-78-9 with competitive price

Cas:530-78-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzoic acid,2-[[3-(trifluoromethyl)phenyl]amino]- 530-78-9

Cas:530-78-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Beluga chemical professional supply High quality Flufenamic Acid CAS 530-78-9 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Made in China a

High quality Flufenamic Acid CAS 530-78-9

Cas:530-78-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzoic acid,2-[[3-(trifluoromethyl)phenyl]amino]-

Cas:530-78-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Benzoic acid,2-[[3-(trifluoromethyl)phenyl]amino]-/ LIDE PHARMA- Factory supply / Best price

Cas:530-78-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Flufenamic acid

Cas:530-78-9

Min.Order:1 Kilogram

FOB Price: $30.0 / 50.0

Type:Lab/Research institutions

inquiry

Jilin Artel New Materials Co., LTD

Price, service, company and transport advantage: 1.place of origin china with super quality by reasonable price. 2. it's customers' right to choose the package (ems, dhl, fedex, ups); 3. it's custo

BEST PRICE/Flufenamic acid

Cas:530-78-9

Min.Order:10 Gram

Negotiable

Type:Trading Company

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Flufenamic acid

Cas:530-78-9

Min.Order:0

Negotiable

Type:Manufacturers

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Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: Flufenamic acid Synonyms: Arlef;Benzoic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-;C.I. 440;CI 440;Paraflu;Parlef;Parlif;Plostene CAS: 530-78-9 MF: C14H10F3NO2 MW: 281.23 EINECS: 208-494-1 Product Categories: Signalling;

Flufenamic acid 99% Manufactuered in China best quality

Cas:530-78-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Flufenamic acid

Cas:530-78-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

FLUFENAMIC ACID

Cas:530-78-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzoic acid,2-[[3-(trifluoromethyl)phenyl]amino]-

Cas:530-78-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Flufenamic Acid

Cas:530-78-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

Flufenamic acid

Cas:530-78-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: Flufenamic Acid CAS No.:530-78-9 Molecule Formula:C14H10F3NO2 Molecule Weight:281.23 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard TESTING ITEMS

High Quality Flufenamic Acid on stock

Cas:530-78-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, in

Enke Flufenamic acid

Cas:530-78-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

Flufenamic acidCAS NO.: 530-78-9

Cas:530-78-9

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Flufenamicacid;2-(3-(trifluoromethyl)phenylamino)benzoicacid

Cas:530-78-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Flufenamic acid CAS NO 530-78-9

Cas:530-78-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Flufenamic acid

Cas:530-78-9

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Flufenamic acid CAS NO 530-78-9

Cas:530-78-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

BEST PRICE/Flufenamic acid CAS NO.530-78-9

Cas:530-78-9

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Flufenamic acid

Cas:530-78-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

2-(3-trifluoromethyl-phenylamino)-benzoic acid (diethylcarbamoylmethyl-methyl-carbamoyloxy)-methyl ester

2-(3-trifluoromethyl-phenylamino)-benzoic acid (diethylcarbamoylmethyl-methyl-carbamoyloxy)-methyl ester

A

sarcosine diethylamide
44897-15-6

sarcosine diethylamide

B

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With human plasma In phosphate buffer at 37℃; pH=7.4;A n/a
B 100%
2-(3-trifluoromethyl-phenylamino)-benzoic acid diethylcarbamoylmethylcarbamoyloxymethyl ester

2-(3-trifluoromethyl-phenylamino)-benzoic acid diethylcarbamoylmethylcarbamoyloxymethyl ester

A

2-amino-N,N-diethylacetamide
34105-57-2

2-amino-N,N-diethylacetamide

B

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With human plasma In phosphate buffer at 37℃; pH=7.4;A n/a
B 100%
2-diethylcarbamoyl-pyrrolidine-1-carboxylic acid 2-(3-trifluoromethyl-phenylamino)-benzoyloxymethyl ester

2-diethylcarbamoyl-pyrrolidine-1-carboxylic acid 2-(3-trifluoromethyl-phenylamino)-benzoyloxymethyl ester

A

flufenamic acid
530-78-9

flufenamic acid

B

(2S)-N',N'-diethylpyrrolidinecarboxamide
41721-01-1

(2S)-N',N'-diethylpyrrolidinecarboxamide

Conditions
ConditionsYield
With human plasma In phosphate buffer at 37℃; pH=7.4;A 100%
B n/a
2-(3-trifluoromethyl-phenylamino)-benzoic acid 1-diethylcarbamoyl-2-phenyl-ethylcarbamoyloxymethyl ester

2-(3-trifluoromethyl-phenylamino)-benzoic acid 1-diethylcarbamoyl-2-phenyl-ethylcarbamoyloxymethyl ester

A

flufenamic acid
530-78-9

flufenamic acid

B

N-(phenylalanyl)-N,N-diethylamine
40847-09-4

N-(phenylalanyl)-N,N-diethylamine

Conditions
ConditionsYield
With human plasma In phosphate buffer at 37℃; pH=7.4;A 100%
B n/a
2-(3-trifluoromethyl-phenylamino)-benzoic acid 1-benzyl-2-morpholin-4-yl-2-oxo-ethylcarbamoyloxymethyl ester

2-(3-trifluoromethyl-phenylamino)-benzoic acid 1-benzyl-2-morpholin-4-yl-2-oxo-ethylcarbamoyloxymethyl ester

A

flufenamic acid
530-78-9

flufenamic acid

B

N-(phenylalanyl)morpholine
141834-13-1

N-(phenylalanyl)morpholine

Conditions
ConditionsYield
With human plasma In phosphate buffer at 37℃; pH=7.4;A 100%
B n/a
2-(3-trifluoromethyl-phenylamino)-benzoic acid 1-benzyl-2-oxo-2-piperidin-1-yl-ethylcarbamoyloxymethyl ester

2-(3-trifluoromethyl-phenylamino)-benzoic acid 1-benzyl-2-oxo-2-piperidin-1-yl-ethylcarbamoyloxymethyl ester

A

flufenamic acid
530-78-9

flufenamic acid

B

(2S)-2-amino-3-phenyl-1-(piperidin-1-yl)propan-1-one
102292-89-7

(2S)-2-amino-3-phenyl-1-(piperidin-1-yl)propan-1-one

Conditions
ConditionsYield
With human plasma In phosphate buffer at 37℃; pH=7.4;A 100%
B n/a
2-((3-(trifluoromethyl)phenyl)amino)benzonitrile
13481-62-4

2-((3-(trifluoromethyl)phenyl)amino)benzonitrile

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water at 95℃; for 20h;98%
3-trifluoromethylaniline
98-16-8

3-trifluoromethylaniline

ortho-chlorobenzoic acid
118-91-2

ortho-chlorobenzoic acid

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With potassium carbonate; copper In N,N-dimethyl-formamide for 2h; Heating;60%
With copper(l) iodide; copper; potassium carbonate In N,N-dimethyl-formamide for 0.333333h; Heating; ultrasonic irradiation;24%
(i) aq. KOH, (ii) /BRN= 387672/, Cu; Multistep reaction;
2-[[3-(trifluoromethyl)phenyl]amino]benzoic acid,methyl ester
2765-91-5

2-[[3-(trifluoromethyl)phenyl]amino]benzoic acid,methyl ester

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With water; potassium hydroxide In ethanol at 100℃; Inert atmosphere;55%
Stage #1: 2-[[3-(trifluoromethyl)phenyl]amino]benzoic acid,methyl ester With potassium hydroxide In ethanol; water at 20 - 100℃; Inert atmosphere;
Stage #2: With hydrogenchloride In water at 0℃; pH=2; Inert atmosphere;
55%
With water; potassium hydroxide In ethanol at 100℃;55%
With hydrazine hydrate In methanol
2-Iodobenzoic acid
88-67-5

2-Iodobenzoic acid

3-trifluoromethylaniline
98-16-8

3-trifluoromethylaniline

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With water; copper; potassium carbonate
With 4-methyl-morpholine; copper(I) oxide In 1,4-dioxane at 100℃; for 3h; Ullmann Condensation; Inert atmosphere;
1-(3'-trifluoromethyl-phenyl)-1,2-dihydro-3,1-benzoxazin-4-one
32509-03-8

1-(3'-trifluoromethyl-phenyl)-1,2-dihydro-3,1-benzoxazin-4-one

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With water In methanol at 20℃; Rate constant; pH from 2.0 to 8.0, half-live-time;
3-trifluoromethylaniline
98-16-8

3-trifluoromethylaniline

potassium 2-bromobenzoate
16497-87-3

potassium 2-bromobenzoate

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With N-ethylmorpholine;; copper diacetate In N,N-dimethyl-formamide at 145℃; for 3h;
1-(3'-trifluoromethyl-phenyl)-2-chloromethyl-1,2-dihydro-3,1-benzoxazin-4-one
137488-39-2

1-(3'-trifluoromethyl-phenyl)-2-chloromethyl-1,2-dihydro-3,1-benzoxazin-4-one

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With water In methanol at 20℃; Rate constant; pH from 2.0 to 9.0, half-live-time;
1-(3'-trifluoromethyl-phenyl)-2-methoxymethyl-1,2-dihydro-3,1-benzoxazin-4-one
137488-40-5

1-(3'-trifluoromethyl-phenyl)-2-methoxymethyl-1,2-dihydro-3,1-benzoxazin-4-one

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With water In methanol at 20℃; Rate constant; pH from 2.0 to 9.0, half-live-time;
1-(3'-trifluoromethyl-phenyl)-2-ethoxycarbonyl-1,2-dihydro-3,1-benzoxazin-4-one
137488-41-6

1-(3'-trifluoromethyl-phenyl)-2-ethoxycarbonyl-1,2-dihydro-3,1-benzoxazin-4-one

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With water In methanol at 37℃; Rate constant; pH from 2.0 to 9.0, half-live-time;
2-<<3-(Trifluormethyl)phenyl>amino>benzoeaeure-2-oxopropylester
137138-25-1

2-<<3-(Trifluormethyl)phenyl>amino>benzoeaeure-2-oxopropylester

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With buffer pH 8.0 In 1,4-dioxane; acetonitrile at 57℃; half-life time of hydrolysis at different pH;
sodium salt of {N-(α,α,α-trifluoro-m-tolyl)anthranilic acid}
1977-00-0

sodium salt of {N-(α,α,α-trifluoro-m-tolyl)anthranilic acid}

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 39 percent / tetrabutylammonium bromide; Et3N / tetrahydrofuran / 24 h / 20 °C
2: 100 percent / human plasma / aq. phosphate buffer / 37 °C / pH 7.4
View Scheme
methyl 2-(trifluoromethylsulfonyloxy)benzoate
17763-70-1

methyl 2-(trifluoromethylsulfonyloxy)benzoate

3-trifluoromethylaniline
98-16-8

3-trifluoromethylaniline

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 120 °C / Inert atmosphere
2: water; potassium hydroxide / ethanol / 100 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1.1: palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 20 - 120 °C / Inert atmosphere
2.1: potassium hydroxide / ethanol; water / 20 - 100 °C / Inert atmosphere
2.2: 0 °C / pH 2 / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 120 °C
2: water; potassium hydroxide / ethanol / 100 °C
View Scheme
3-trifluoromethylaniline
98-16-8

3-trifluoromethylaniline

2-bromobenzoic-acid
88-65-3

2-bromobenzoic-acid

flufenamic acid
530-78-9

flufenamic acid

Conditions
ConditionsYield
With 4-methyl-morpholine; copper(II) oxide In 1,4-dioxane Inert atmosphere; Reflux;
flufenamic acid
530-78-9

flufenamic acid

1-Adamantanamine
768-94-5

1-Adamantanamine

C10H17N*C14H10F3NO2

C10H17N*C14H10F3NO2

Conditions
ConditionsYield
In methanol at 20℃;100%
flufenamic acid
530-78-9

flufenamic acid

naphthalen-2-ylmethylamine
2018-90-8

naphthalen-2-ylmethylamine

C14H10F3NO2*C11H11N

C14H10F3NO2*C11H11N

Conditions
ConditionsYield
In methanol at 20℃;100%
tryptamine
61-54-1

tryptamine

flufenamic acid
530-78-9

flufenamic acid

C14H10F3NO2*C10H12N2

C14H10F3NO2*C10H12N2

Conditions
ConditionsYield
In methanol at 20℃;100%
flufenamic acid
530-78-9

flufenamic acid

serinol
534-03-2

serinol

C14H10F3NO2*C3H9NO2

C14H10F3NO2*C3H9NO2

Conditions
ConditionsYield
In methanol at 20℃;100%
flufenamic acid
530-78-9

flufenamic acid

2-(3,4-dimethoxyphenyl)-ethylamine
120-20-7

2-(3,4-dimethoxyphenyl)-ethylamine

C14H10F3NO2*C10H15NO2

C14H10F3NO2*C10H15NO2

Conditions
ConditionsYield
In methanol at 20℃;100%
flufenamic acid
530-78-9

flufenamic acid

phenethylamine
64-04-0

phenethylamine

C14H10F3NO2*C8H11N

C14H10F3NO2*C8H11N

Conditions
ConditionsYield
In methanol at 20℃;100%
flufenamic acid
530-78-9

flufenamic acid

N-(3-trifluoromethylphenyl)aniline
101-23-5

N-(3-trifluoromethylphenyl)aniline

Conditions
ConditionsYield
With triethylsilane; palladium diacetate; 2,2-dimethylpropanoic anhydride; 1,4-di(diphenylphosphino)-butane In toluene at 160℃; for 15h; chemoselective reaction;97%
flufenamic acid
530-78-9

flufenamic acid

2-(3-(trifluoromethyl)phenylamino)benzohydrazide
39492-79-0

2-(3-(trifluoromethyl)phenylamino)benzohydrazide

Conditions
ConditionsYield
With hydrazine hydrate at 250℃; under 12929 Torr; for 0.0666667h; Microwave irradiation; Neat (no solvent);96%
Multi-step reaction with 2 steps
1: sulfuric acid / Reflux
2: hydrazine hydrate / 15 h / Reflux
View Scheme
flufenamic acid
530-78-9

flufenamic acid

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethyl (2-((3-(trifluoromethyl)phenyl)amino)phenyl)phosphonate

diethyl (2-((3-(trifluoromethyl)phenyl)amino)phenyl)phosphonate

Conditions
ConditionsYield
With palladium diacetate; 2,2-dimethylpropanoic anhydride; triethylamine; 1,4-di(diphenylphosphino)-butane In 1,4-dioxane at 160℃; for 15h; Inert atmosphere; Schlenk technique;96%
formaldehyd
50-00-0

formaldehyd

flufenamic acid
530-78-9

flufenamic acid

1-(3'-trifluoromethyl-phenyl)-1,2-dihydro-3,1-benzoxazin-4-one
32509-03-8

1-(3'-trifluoromethyl-phenyl)-1,2-dihydro-3,1-benzoxazin-4-one

Conditions
ConditionsYield
With zinc(II) chloride In dichloromethane for 2h; Ambient temperature;93%
In ethanol; water for 1h; Heating;
flufenamic acid
530-78-9

flufenamic acid

o-toluidine
95-53-4

o-toluidine

3-Trifluormethyl-2'-(2-methyl-phenylcarbamoyl)-diphenylamin
21240-02-8

3-Trifluormethyl-2'-(2-methyl-phenylcarbamoyl)-diphenylamin

Conditions
ConditionsYield
With N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride; triethylamine In dichloromethane at 20 - 25℃; for 1h;92%
Thiomorpholin
123-90-0

Thiomorpholin

flufenamic acid
530-78-9

flufenamic acid

thiomorpholino(2-((3-(trifluoromethyl)phenyl)amino)phenyl)methanone

thiomorpholino(2-((3-(trifluoromethyl)phenyl)amino)phenyl)methanone

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 4h;92%
flufenamic acid
530-78-9

flufenamic acid

2-<<3-(trifluoromethyl)phenyl>amino>benzamide
13481-61-3

2-<<3-(trifluoromethyl)phenyl>amino>benzamide

Conditions
ConditionsYield
Stage #1: flufenamic acid With thionyl chloride In toluene for 1h; Reflux;
Stage #2: With ammonium hydroxide
92%
Stage #1: flufenamic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran at 50℃; for 0.5h;
Stage #2: With ammonium hydroxide; 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at 50℃; for 5h;
70.3%
Magnolol
528-43-8

Magnolol

flufenamic acid
530-78-9

flufenamic acid

5,5'-diallyl-2'-hydroxy-[1,1'-biphenyl]-2-yl-2-((3-(trifluoromethyl)phenyl)amino)benzoate

5,5'-diallyl-2'-hydroxy-[1,1'-biphenyl]-2-yl-2-((3-(trifluoromethyl)phenyl)amino)benzoate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 1h;91%
With dmap In dichloromethane at 25 - 30℃;91%
flufenamic acid
530-78-9

flufenamic acid

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

1-(3'-trifluoromethyl-phenyl)-2-ethoxy-1,2-dihydro-3,1-benzoxazin-4-one
137488-38-1

1-(3'-trifluoromethyl-phenyl)-2-ethoxy-1,2-dihydro-3,1-benzoxazin-4-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 4h; Heating;89%
flufenamic acid
530-78-9

flufenamic acid

trimethyl orthoformate
149-73-5

trimethyl orthoformate

1-(3'-trifluoromethyl-phenyl)-2-methoxy-1,2-dihydro-3,1-benzoxazin-4-one
137488-37-0

1-(3'-trifluoromethyl-phenyl)-2-methoxy-1,2-dihydro-3,1-benzoxazin-4-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 4h; Heating;89%
flufenamic acid
530-78-9

flufenamic acid

acetic acid
64-19-7

acetic acid

2-(dimethylamino)ethyl 2-[[3-trifluoromethylphenyl]amino]thiobenzoate acetate

2-(dimethylamino)ethyl 2-[[3-trifluoromethylphenyl]amino]thiobenzoate acetate

Conditions
ConditionsYield
Stage #1: captamine; flufenamic acid With dicyclohexyl-carbodiimide In chloroform at 20℃; for 3h;
Stage #2: acetic acid In chloroform
88.5%
flufenamic acid
530-78-9

flufenamic acid

thiophenol
108-98-5

thiophenol

S-phenyl 2-((3-(trifluoromethyl)phenyl)amino)benzothioate

S-phenyl 2-((3-(trifluoromethyl)phenyl)amino)benzothioate

Conditions
ConditionsYield
Stage #1: flufenamic acid With oxalyl dichloride In dichloromethane
Stage #2: thiophenol With triethylamine In dichloromethane
88%
flufenamic acid
530-78-9

flufenamic acid

R,S-5-Brom-2,2-dimethyl-1,3-dioxolan-4-on
134674-19-4

R,S-5-Brom-2,2-dimethyl-1,3-dioxolan-4-on

2-<3-(Trifluormethyl)phenylamino>-benzoesaeure-(2,2-dimethyl-1,3-dioxolan-4-on-5-yl)ester
134674-24-1

2-<3-(Trifluormethyl)phenylamino>-benzoesaeure-(2,2-dimethyl-1,3-dioxolan-4-on-5-yl)ester

Conditions
ConditionsYield
With triethylamine In acetone Ambient temperature;87%
flufenamic acid
530-78-9

flufenamic acid

(2E)-3-phenyl-2-propen-1-ol
4407-36-7

(2E)-3-phenyl-2-propen-1-ol

cinnamyl 2-(3-(trifluoromethyl)phenylamino)benzoate

cinnamyl 2-(3-(trifluoromethyl)phenylamino)benzoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide at 20℃; for 4h;87%
methanol
67-56-1

methanol

flufenamic acid
530-78-9

flufenamic acid

2-[[3-(trifluoromethyl)phenyl]amino]benzoic acid,methyl ester
2765-91-5

2-[[3-(trifluoromethyl)phenyl]amino]benzoic acid,methyl ester

Conditions
ConditionsYield
With sulfuric acid for 12h; Heating;86%
With sulfuric acid for 100h; Heating;
With sulfuric acid for 16h; Heating;
With sulfuric acid Reflux;
chloroacetaldehyde dimethyl acetal
97-97-2

chloroacetaldehyde dimethyl acetal

flufenamic acid
530-78-9

flufenamic acid

1-(3'-trifluoromethyl-phenyl)-2-chloromethyl-1,2-dihydro-3,1-benzoxazin-4-one
137488-39-2

1-(3'-trifluoromethyl-phenyl)-2-chloromethyl-1,2-dihydro-3,1-benzoxazin-4-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 4h; Heating;86%
flufenamic acid
530-78-9

flufenamic acid

Ethyl diethoxyacetate
6065-82-3

Ethyl diethoxyacetate

1-(3'-trifluoromethyl-phenyl)-2-ethoxycarbonyl-1,2-dihydro-3,1-benzoxazin-4-one
137488-41-6

1-(3'-trifluoromethyl-phenyl)-2-ethoxycarbonyl-1,2-dihydro-3,1-benzoxazin-4-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 5h; Heating;86%

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