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Hangzhou Think Chemical Co. Ltd

4-Chloro-5-Ethoxycarbonyl-2-Methylthiopyrimidine (ECM) [CAS:5909-24-0] 3-Chloro-4-Methoxybenzylamine HCl (CMA) [CAS:41965-95-1] HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufactur

4-Chloro-5-Ethoxycarbonyl-2-Methylthiopyrimidine

Cas:5909-24-0

Min.Order:1 Kilogram

FOB Price: $200.0

Type:Other

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ZHEJIANG JIUZHOU CHEM CO.,LTD

White to light yellow to beige Crystalline Powder Appearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

Cas:5909-24-0

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

Cas:5909-24-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/681.html Product Name Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate CAS

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

Cas:5909-24-0

Min.Order:1 Gram

FOB Price: $55.0

Type:Lab/Research institutions

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate manufacturer with low price

Cas:5909-24-0

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White powder Storage:cool dry place Package:25kg/drum Application:pharmaceutical intermediate Transportation:by c

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

Ethyl 4-Chloro-2-(Methylthio)pyriMidine-5-carboxylate

Cas:5909-24-0

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

Cas:5909-24-0

Min.Order:1

Negotiable

Type:Other

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

Cas:5909-24-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Chloro-(2-methylthio)-5-pyrimidinecarboxylic acid ethyl ester

Cas:5909-24-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate Basic information Product Name: Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate Synonyms: BUTTPARK 45\03-53;ETHYL 4-CHLORO-2-M

5909-24-0

Cas:5909-24-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate cas 5909-24-0

Cas:5909-24-0

Min.Order:1 Kilogram

FOB Price: $48.0 / 58.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 5909-24-0 with best quality

Cas:5909-24-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylat Synonyms Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylat;BUTTPARK 45 CAS: 5909-24-0 MF:

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate CAS:5909-24-0

Cas:5909-24-0

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod

5-Pyrimidinecarboxylicacid, 4-chloro-2-(methylthio)-, ethyl ester

Cas:5909-24-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

2-METHYLTHIO-4-CHLORO-5-ETHOXYCARBONYLPYRIMIDINECAS NO.:5909-24-0

Cas:5909-24-0

Min.Order:1 Gram

FOB Price: $3.0

Type:Lab/Research institutions

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Powder Storage:Store in sealed containers at cool & dry plac

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate CAS NO 5909-24-0

Cas:5909-24-0

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-Pyrimidinecarboxylicacid, 4-chloro-2-(methylthio)-, ethyl ester 5909-24-0

Cas:5909-24-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Product Name: Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate CAS: 5909-24-0 MF: C8H9ClN2O2S MW: 232.69 EINECS: 227-619-0 Mol File: 5909-24-0.mol Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate Structure Ethyl 4-chloro-2-m

Ethyl-4-chloro-2-(methylthio)pyrimidine-5-carboxylate

Cas:5909-24-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate CAS: 5909-24-0

Cas:5909-24-0

Min.Order:1 Kilogram

FOB Price: $113.0 / 120.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Ethyl 4-chloro -2-methylthio-5-pyrimidinecarboxylate CAS: 5909-24-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, speciali

Ethyl 4-chloro -2-methylthio-5-pyrimidinecarboxylate CAS: 5909-24-0

Cas:5909-24-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate

Cas:5909-24-0

Min.Order:1 Kilogram

FOB Price: $7.0 / 9.0

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

TIANFU-CHEM - Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

Cas:5909-24-0

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Triumph International Development Limilted

Appearance:white powder/crystal Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/A

ethyl 4-chloro-2-methylthio-5-pyrimidine-carboxyl

Cas:5909-24-0

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Ethyl 4-chloro-2-methylthiopyrimidine-5-carboxylate

Cas:5909-24-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

Cas:5909-24-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

ethyl 4-chloro-2-(methylsulfanyl)pyrimidine-5-carboxylate

Cas:5909-24-0

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

our strengths: 1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line) 2: Various payment items accepted (Btc; MoneyGram; WU) 3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging) 4: Efficient delivery

ethyl 4-chloro-2-methylthio-5-pyrimidine-carboxyl

Cas:5909-24-0

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

Cas:5909-24-0

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate/High quality/Best price

Cas:5909-24-0

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Synthetic route

ethyl 4-hydroxy-2-(methylthio)pyrimidine-5-carboxylate
53554-29-3

ethyl 4-hydroxy-2-(methylthio)pyrimidine-5-carboxylate

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
With thionyl chloride at 60℃; for 3h;92%
With N,N-diethylaniline; trichlorophosphate for 5h; Heating / reflux;77%
With trichlorophosphate In acetonitrile for 6h; Reagent/catalyst; Reflux;77%
sodium 5-(ethoxycarbonyl)-2-(methylthio)-4-oxo-4H-pyrimidin-3-ide

sodium 5-(ethoxycarbonyl)-2-(methylthio)-4-oxo-4H-pyrimidin-3-ide

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
Stage #1: sodium 5-(ethoxycarbonyl)-2-(methylthio)-4-oxo-4H-pyrimidin-3-ide With thionyl chloride In N,N-dimethyl-formamide; toluene at 20 - 30℃; for 0.5h; Large scale;
Stage #2: With trichlorophosphate In N,N-dimethyl-formamide; toluene at 55 - 65℃; for 1.5h; Large scale;
84.5%
With trichlorophosphate for 3h; Reflux;
With trichlorophosphate at 0℃; for 5h; Reflux;
ethyl 3,4-dihydro-2-methylthio-4-oxopyrimidine-5-carboxylate
53554-29-3

ethyl 3,4-dihydro-2-methylthio-4-oxopyrimidine-5-carboxylate

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
With thionyl chloride
With trichlorophosphate
With trichlorophosphate at 100℃; for 3h;
diethyl 2-ethoxymethylenemalonate
87-13-8

diethyl 2-ethoxymethylenemalonate

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: EtONa / ethanol
2: POCl3
View Scheme
Multi-step reaction with 2 steps
1: aqueous KOH
2: POCl3
View Scheme
Multi-step reaction with 2 steps
1.1: sodium hydroxide / water / 0.08 h / 20 °C
1.2: 24 h / 20 °C
2.1: trichlorophosphate / 3 h / Reflux
View Scheme
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

methylamine
74-89-5

methylamine

4-methylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester
76360-82-2

4-methylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
In ethanol; dichloromethane at 0℃; for 0.5h;100%
With triethylamine In tetrahydrofuran at 50℃;100%
at 0℃; for 0.5h;100%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

ethyl 4-hydrazinyl-2-(methylsulfanyl)pyrimidine-5-carboxylate
117147-06-5

ethyl 4-hydrazinyl-2-(methylsulfanyl)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With hydrazine hydrate In ethanol at 0℃; for 1h;100%
With hydrazine hydrate In ethanol at 0℃; for 1h;91.8%
With hydrazine hydrate In ethanol at 0 - 20℃; for 1h;85.71%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

Cyclopentamine
1003-03-8

Cyclopentamine

4-cyclopentylamino-2-(methylsulfanyl)pyrimidine-5-carboxylic acid ethyl ester
211245-62-4

4-cyclopentylamino-2-(methylsulfanyl)pyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane100%
With triethylamine In dichloromethane for 0.75h; Heating / reflux;97%
With triethylamine In tetrahydrofuran at 20℃; for 1h;96.1%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

(3-chloro-4-methoxyphenyl)methanamine
115514-77-7

(3-chloro-4-methoxyphenyl)methanamine

ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylate
330785-81-4

ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃;100%
With triethylamine In acetone at 20℃; for 3h;87%
With triethylamine In dichloromethane at 20℃; for 10h;76%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

N'-cyclohexyl-hydrazine carboxylic acid tert-butyl ester
60295-21-8

N'-cyclohexyl-hydrazine carboxylic acid tert-butyl ester

C19H30N4O4S
900502-62-7

C19H30N4O4S

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃;100%
With triethylamine In tetrahydrofuran at 20℃;100%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

N-(((2S,4R)-4-hydroxypyrrolidin-2-yl)methyl)-2-nitrobenzenesulfonamide
1410975-83-5

N-(((2S,4R)-4-hydroxypyrrolidin-2-yl)methyl)-2-nitrobenzenesulfonamide

ethyl 4-((2S,4R)-4-hydroxy-2-((2-nitrophenylsulfonamido)methyl)pyrrolidin-1-yl)-2-(methylthio)pyrimidine-5-carboxylate
1410975-85-7

ethyl 4-((2S,4R)-4-hydroxy-2-((2-nitrophenylsulfonamido)methyl)pyrrolidin-1-yl)-2-(methylthio)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 90℃; for 1.5h;100%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

ethylamine
75-04-7

ethylamine

4-ethylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester
185040-33-9

4-ethylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
In water; acetonitrile at 0 - 20℃; for 8h;99.1%
With triethylamine In tetrahydrofuran; water at 20℃; for 4h;93%
With triethylamine In tetrahydrofuran at 20℃;92%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

ethyl 4-amino-2-methylmercaptopyrimidine-5-carboxylate
776-53-4

ethyl 4-amino-2-methylmercaptopyrimidine-5-carboxylate

Conditions
ConditionsYield
With ammonium hydroxide; triethylamine In tetrahydrofuran; water at 30℃; for 2h;99%
With ammonium hydroxide; triethylamine In tetrahydrofuran for 2h;99%
With ammonium hydroxide; triethylamine In tetrahydrofuran at 30℃; for 2h;99%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

isopropylamine
75-31-0

isopropylamine

4-isopropylamino-2-(methylsulfanyl)pyrimidine-5-carboxylic acid ethyl ester
25693-79-2

4-isopropylamino-2-(methylsulfanyl)pyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
In water; acetonitrile at 0 - 20℃; for 8h;99%
In 1-methyl-pyrrolidin-2-one at 60℃;98%
With triethylamine In tetrahydrofuran at 20℃;95%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

ethyl 3-methylaminopropionate
2213-08-3

ethyl 3-methylaminopropionate

ethyl 4-((3-ethoxy-3-oxopropyl)(methyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
625106-58-3

ethyl 4-((3-ethoxy-3-oxopropyl)(methyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With triethylamine In acetonitrile for 16h; Reflux;99%
In tetrahydrofuran at 50℃; for 1h; Inert atmosphere;43%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

cycloheptanamine
5452-35-7

cycloheptanamine

ethyl 4-(cycloheptylamino)-2-(methylsulfanyl)pyrimidine-5-carboxylate

ethyl 4-(cycloheptylamino)-2-(methylsulfanyl)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 18h;99%
With triethylamine In N,N-dimethyl-formamide at 20℃; for 4h;90%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

ethyl 2-(methylthio)pyrimidine-5-carboxylate
73781-88-1

ethyl 2-(methylthio)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen; sodium carbonate In ethanol under 3102.97 Torr; for 48h;98.2%
With hydrogen; sodium hydrogencarbonate; palladium 10% on activated carbon In ethanol for 48h;70%
With acetic acid; zinc In tetrahydrofuran for 6h; Heating / reflux;63%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

2-ethyl-N-butylamine
617-79-8

2-ethyl-N-butylamine

methyl 4-[(2-ethylbutyl)amino]-2-(methylthio)pyrimidine-5-carboxylate
686266-25-1

methyl 4-[(2-ethylbutyl)amino]-2-(methylthio)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With triethylamine at 20℃; for 18h;98%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

methylamine hydrochloride
593-51-1

methylamine hydrochloride

4-methylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester
76360-82-2

4-methylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 0 - 20℃; for 15h; Inert atmosphere;98%
With triethylamine In tetrahydrofuran at 0 - 20℃; for 15h; Inert atmosphere;94%
With N-ethyl-N,N-diisopropylamine In acetonitrile at 100℃; for 3h;
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

N-(((2S,4R)-4-fluoropyrrolidine-2-yl)methyl)-2-nitrobenzenesulfonamide
1410975-65-3

N-(((2S,4R)-4-fluoropyrrolidine-2-yl)methyl)-2-nitrobenzenesulfonamide

ethyl 4-((2S,4R)-4-fluoro-2-((2-nitrophenylsulfonamido)pyrrolidin-1-yl)-2-(methylthio)pyrimidine)-5-carboxylate

ethyl 4-((2S,4R)-4-fluoro-2-((2-nitrophenylsulfonamido)pyrrolidin-1-yl)-2-(methylthio)pyrimidine)-5-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 90℃; for 2.5h;97%
1-(3-fluoro-4-methoxyphenyl)methanamine
123652-95-9

1-(3-fluoro-4-methoxyphenyl)methanamine

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

ethyl 4-((3-fluoro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

ethyl 4-((3-fluoro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.5h;97%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

benzylamine
100-46-9

benzylamine

ethyl 4-(benzylamino)-2-(methylthio)pyrimidine-5-carboxylate
100973-67-9

ethyl 4-(benzylamino)-2-(methylthio)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 5h;96%
With N-ethyl-N,N-diisopropylamine In acetonitrile
With N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 20℃;
With N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 0 - 26℃;
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

(3-aminophenyl)carbamic acid tert-butyl ester
68621-88-5

(3-aminophenyl)carbamic acid tert-butyl ester

4-(3-tert-butoxycarbonylaminoanilino)-2-methylmercaptopyrimidine-5-carbonic acid ethyl ester
1363161-14-1

4-(3-tert-butoxycarbonylaminoanilino)-2-methylmercaptopyrimidine-5-carbonic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; Inert atmosphere;96%
With potassium carbonate In N,N-dimethyl-formamide at 80℃; Inert atmosphere;96%
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 2h;95%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

cis-(2-aminocyclopentyl)methanol

cis-(2-aminocyclopentyl)methanol

ethyl 4-(cis-2-(hydroxymethyl)cyclopentylamino)-2-(methylthio)pyrimidine-5-carboxylate

ethyl 4-(cis-2-(hydroxymethyl)cyclopentylamino)-2-(methylthio)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In ethanol at 60℃; for 2.5h;96%
C12H22N2O2

C12H22N2O2

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

C20H30N4O4S

C20H30N4O4S

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 4 - 65℃; for 17h;95.5%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

1-ethylhydrazinecarboxylic acid tert-butyl ester
955370-01-1

1-ethylhydrazinecarboxylic acid tert-butyl ester

ethyl 4-(2-(tert-butoxycarbonyl)-2-ethylhydrazinyl)-2-(methylthio)pyrimidine-5-carboxylate

ethyl 4-(2-(tert-butoxycarbonyl)-2-ethylhydrazinyl)-2-(methylthio)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 60℃; for 16h;95.03%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 60℃; for 16h;95%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

Cyclopropylamine
765-30-0

Cyclopropylamine

4-cyclopropylamino-2-(methylsulfanyl)pyrimidine-5-carboxylic acid ethyl ester
651734-65-5

4-cyclopropylamino-2-(methylsulfanyl)pyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃;95%
With triethylamine In acetonitrile at 0 - 20℃; for 4h;92%
With triethylamine In tetrahydrofuran at 20℃;90%
With triethylamine In tetrahydrofuran at 20℃;90%
With triethylamine In dichloromethane at 15 - 42℃; for 2h; Inert atmosphere;
aqueous ethylamine

aqueous ethylamine

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

4-ethylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester
185040-33-9

4-ethylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran95%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

1-amino-7-methoxyindane hydrochloride
1187160-18-4

1-amino-7-methoxyindane hydrochloride

ethyl 4-(7-methoxy-2,3-dihydro-1H-inden-1ylamino)-2-(methylthio)pyrimidine-5-carboxylate
1232030-41-9

ethyl 4-(7-methoxy-2,3-dihydro-1H-inden-1ylamino)-2-(methylthio)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 0 - 20℃;95%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

1-aminobicyclo<1.1.1>pentane hydrochloride
22287-35-0

1-aminobicyclo<1.1.1>pentane hydrochloride

ethyl 4-(bicyclo[1.1.1]pentan-1-ylamino)-2-(methylthio)pyrimidine-5-carboxylate
1403865-19-9

ethyl 4-(bicyclo[1.1.1]pentan-1-ylamino)-2-(methylthio)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃; for 48h; Inert atmosphere;95%
With triethylamine In tetrahydrofuran at 20℃; for 72h;80%
With N-ethyl-N,N-diisopropylamine In ethanol at 20℃;
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

N-butylamine
109-73-9

N-butylamine

4-butylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester
1027417-40-8

4-butylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃;95%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

1-pentanamine
110-58-7

1-pentanamine

2-methylsulfanyl-4-pentylamino-pyrimidine-5-carboxylic acid ethyl ester
1537216-06-0

2-methylsulfanyl-4-pentylamino-pyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃;95%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

p-benzyloxyaniline
6373-46-2

p-benzyloxyaniline

ethyl 4-((4-(benzyloxy)phenyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

ethyl 4-((4-(benzyloxy)phenyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dimethylsulfoxide-d6 at 20 - 80℃; for 2h;95%
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

(+/-)-trans-3-(tert-butyl-dimethylsilanyloxy)-cyclopentylamine

(+/-)-trans-3-(tert-butyl-dimethylsilanyloxy)-cyclopentylamine

4-[3-(tert-butyldimethylsilanyloxy)cyclopentylamino]-2-methylsulfanylpyrimidine-5-carboxylic acid ethyl ester

4-[3-(tert-butyldimethylsilanyloxy)cyclopentylamino]-2-methylsulfanylpyrimidine-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane for 0.5h; Heating;94%
4-(4-amino-2-fluorophenoxy)pyridin-2-carboxamide
868733-71-5

4-(4-amino-2-fluorophenoxy)pyridin-2-carboxamide

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
5909-24-0

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

ethyl 4-(4-(2-carbamoylpyridin-4-yloxy)-3-fluorophenylamino)-2-(methylthio)pyrimidine-5-carboxylate hydrochloride

ethyl 4-(4-(2-carbamoylpyridin-4-yloxy)-3-fluorophenylamino)-2-(methylthio)pyrimidine-5-carboxylate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane; 1-methyl-pyrrolidin-2-one93%

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