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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

High purity 5-Methylisatin 98% TOP1 supplier in China

Cas:608-05-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Methylisatin supplier in China

Cas:608-05-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

5-Methyl-Indole-2, 3-Dione

Cas:608-05-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Methylisatin

Cas:608-05-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Leader Biochemical Group

About Product Details CAS: 6

China Biggest factory Supply High Quality 5-Methylisatin CAS 608-05-9

Cas:608-05-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 5.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

5-Methylisatin

Cas:608-05-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

C9H7NO2 5-Methylisatin 608-05-9

Cas:608-05-9

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 608-05-9 with best quality

Cas:608-05-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H-Indole-2,3-dione,5-methyl- 608-05-9

Cas:608-05-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

5-Methylisatin CAS:608-05-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate

5-Methylisatin CAS:608-05-9

Cas:608-05-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1H-Indole-2,3-dione,5-methyl-

Cas:608-05-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. Advantage cof, mof ligand manufacturer Product Detail English Name: 5-methylisatin Other nam

wholesale 99% 5-Methylisatin, 98% CAS:608-05-9

Cas:608-05-9

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:608-05-9

Cas:608-05-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

5-Methylisatin

Cas:608-05-9

Min.Order:1 Kilogram

FOB Price: $30.0 / 50.0

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Methylisatin

Cas:608-05-9

Min.Order:0

Negotiable

Type:Manufacturers

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Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: 5-Methylisatin Synonyms: AURORA 1898;BUTTPARK 34\07-89;IFLAB-BB F0266-0774;5-METHYL-1H-INDOLE-2,3-DIONE;5-METHYLISATIN;5-METHYLINDOLE-2,3-DIONE;AKOS BBS-00000995;AKOS AU36-M121 CAS: 608-05-9 MF: C9H7NO2 MW: 161.16 EINECS: 21

5-Methylisatin 99% Manufactuered in China best quality

Cas:608-05-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

5-methylisatin

Cas:608-05-9

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-Methylisatin

Cas:608-05-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

5-METHYLISATIN

Cas:608-05-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Methylisatin

Cas:608-05-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-methylisatin

Cas:608-05-9

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 5-Methylisatin

Cas:608-05-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

5-methylisatin

Cas:608-05-9

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

5-Methylisatin

Cas:608-05-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

5-Methylisatin Chemical Properties Melting point 180 °C (dec.) (lit.) density 1.301±0.06 g/cm3(Predicted) solubility methanol: soluble25mg/mL, clear to slightly hazy, orange to red form crystalline pka 10.42±0.20(

5-Methylisatin

Cas:608-05-9

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

5-methylisatin

Cas:608-05-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Siwei Development Group Ltd.

Product name: 5-Methylindoline--2,3-Dione CAS No.:608-05-9 Molecule Formula:C9H7NO2 Molecule Weight:161.16 Purity: 99.0% Package: 25kg/drum Description:Yellow to reddish crystalline powder Manufacture Standards:Enterprise Standard

Best Quality 5-Methylindoline--2,3-Dione

Cas:608-05-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

5-Methylisatin

Cas:608-05-9

Min.Order:0

Negotiable

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

5-methylisatin

Cas:608-05-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

wholesale 99% 5-Methylisatin, 98% CAS:608-05-9 CAS NO.608-05-9

Cas:608-05-9

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

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Synthetic route

2-Diethylamino-5-methyl-indol-3-on

2-Diethylamino-5-methyl-indol-3-on

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With hydrogenchloride In ethanol100%
2-(2-amino-5-methylphenyl)-N-hexyl-2-oxoacetamide

2-(2-amino-5-methylphenyl)-N-hexyl-2-oxoacetamide

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran; water at 20℃;99%
2-hydroxyimino-N-p-tolyl-acetamide
1132-40-7

2-hydroxyimino-N-p-tolyl-acetamide

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With sulfuric acid at 20 - 30℃; for 1.66667h;97.3%
Stage #1: 2-hydroxyimino-N-p-tolyl-acetamide With sulfuric acid at 60 - 80℃;
Stage #2: With water for 0.5h; Cooling with ice;
86.9%
Stage #1: 2-hydroxyimino-N-p-tolyl-acetamide With sulfuric acid at 20℃; Sandmeyer reaction;
Stage #2: With water Cooling with ice;
85%
N-tert-butyl-(2-amino-5-methyl-phenyl)-glyoxylamide

N-tert-butyl-(2-amino-5-methyl-phenyl)-glyoxylamide

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran; water at 20℃; for 5h;92.7%
5-methylindolin-2-one
3484-35-3

5-methylindolin-2-one

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With oxygen; sodium iodide In tetrahydrofuran at 60℃; for 12h; Schlenk technique; chemoselective reaction;92%
Multi-step reaction with 2 steps
1: CuBr2 / ethyl acetate / 80 °C
2: water / methanol / 2 h / Heating
View Scheme
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; oxygen In acetonitrile at 20℃; for 18h;
5-methyl-2,3-dihydro-1H-indole
65826-95-1

5-methyl-2,3-dihydro-1H-indole

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With iodine pentoxide In dimethyl sulfoxide at 80℃;88%
With o-iodosobenzoic acid; oxygen In dimethyl sulfoxide at 80℃; for 12h; Green chemistry;83%
(Z)-2-(hydroxylimino)-N-p-tolylacetamide
1233474-66-2

(Z)-2-(hydroxylimino)-N-p-tolylacetamide

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With sulfuric acid at 50 - 80℃;86.9%
5-methyl-1H-indole
614-96-0

5-methyl-1H-indole

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With oxygen; Rose Bengal lactone In water; N,N-dimethyl-formamide for 18h; Inert atmosphere; Irradiation;86%
With N-iodo-succinimide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dimethyl sulfoxide at 15 - 25℃; for 4h;83%
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; oxygen In acetonitrile at 20℃; for 11h;82%
With tert.-butylhydroperoxide; iodine In dimethyl sulfoxide at 80℃; for 24h;64%
C10H7N3O2

C10H7N3O2

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With copper(I) bromide In water; benzonitrile at 140℃; for 4h; Inert atmosphere;86%
chloral hydrate
302-17-0

chloral hydrate

p-toluidine
106-49-0

p-toluidine

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
Stage #1: chloral hydrate; p-toluidine With sulfuric acid; hydroxylamine hydrochloride; sodium sulfate In water at 130℃; for 0.5h;
Stage #2: With sulfuric acid at 50 - 70℃; for 1h;
80%
With hydrogenchloride; hydroxylamine hydrochloride; sodium sulfate In water at 90℃; for 0.0833333h;66.3%
Stage #1: chloral hydrate; p-toluidine With hydrogenchloride; hydroxylamine hydrochloride; sodium sulfate In water
Stage #2: With sulfuric acid at 60 - 80℃;
56%
5-methylindole-3-carboxaldehyde
52562-50-2

5-methylindole-3-carboxaldehyde

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With sodium chloride In water; acetonitrile at 50℃; for 2h; Green chemistry;80%
oxalyl dichloride
79-37-8

oxalyl dichloride

p-toluidine
106-49-0

p-toluidine

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With H-β zeolite In 1,2-dichloro-ethane at 80℃; for 24h; Inert atmosphere;76%
carbon monoxide
201230-82-2

carbon monoxide

N'-(2-Bromo-4-methylphenyl)-N,N-dimethylurea
58226-34-9

N'-(2-Bromo-4-methylphenyl)-N,N-dimethylurea

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
Stage #1: N'-(2-Bromo-4-methylphenyl)-N,N-dimethylurea With methyllithium In tetrahydrofuran; diethyl ether at 0℃;
Stage #2: With tert.-butyl lithium In tetrahydrofuran; diethyl ether; n-heptane at 0℃; for 1h;
Stage #3: carbon monoxide In tetrahydrofuran; diethyl ether; n-heptane at 0℃; for 0.5h;
72%
Yield given; Multistep reaction;
3-(p-tolylimino)-5-methyl-N-p-tolyl-3H-indole-2-amine
29650-23-5

3-(p-tolylimino)-5-methyl-N-p-tolyl-3H-indole-2-amine

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With hydrogenchloride; acetic acid In water for 0.333333h; Reflux;68%
5-methylisatin-3-oxime
13208-98-5

5-methylisatin-3-oxime

triisopropyl phosphite
116-17-6

triisopropyl phosphite

A

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

B

(3-Hydroxy-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-phosphonic acid diisopropyl ester

(3-Hydroxy-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-phosphonic acid diisopropyl ester

C

(3-Hydroxyamino-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-phosphonic acid diisopropyl ester

(3-Hydroxyamino-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-phosphonic acid diisopropyl ester

Conditions
ConditionsYield
With acetic acid at 100℃; for 12h;A n/a
B n/a
C 60%
5-methylisatin-3-oxime
13208-98-5

5-methylisatin-3-oxime

triethyl phosphite
122-52-1

triethyl phosphite

A

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

B

diethyl 3-hydroxy-5-methyl-2-oxoindolin-3-ylphosphonate

diethyl 3-hydroxy-5-methyl-2-oxoindolin-3-ylphosphonate

C

(3-Hydroxyamino-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-phosphonic acid diethyl ester

(3-Hydroxyamino-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-phosphonic acid diethyl ester

Conditions
ConditionsYield
With acetic acid at 100℃; for 12h;A n/a
B n/a
C 60%
Glyoxal
131543-46-9

Glyoxal

p-toluidine
106-49-0

p-toluidine

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With copper(II) choride dihydrate; caesium carbonate; trifluoroacetic acid In 2-methyltetrahydrofuran; water at 70℃; for 5h; Schlenk technique; Inert atmosphere;47%
oxalyl dichloride
79-37-8

oxalyl dichloride

p-toluidine hydrochloride
540-23-8

p-toluidine hydrochloride

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With nitrobenzene Erwaermen des Reaktionsgemisches mit Aluminiumchlorid;
5-methyl-2-nitrobenzaldehyde
5858-28-6

5-methyl-2-nitrobenzaldehyde

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With acetone Man oxydiert das (nicht isolierte) <6-Nitro-α-oxy-3-methyl-benzyl>-aceton mit Kaliumpermanganat in sodaalkalischer Loesung bei 60-70grad;
2-hydroxyimino-N-p-tolyl-acetamide
1132-40-7

2-hydroxyimino-N-p-tolyl-acetamide

A

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

B

p-tolyl-oxalamide
42868-90-6

p-tolyl-oxalamide

Conditions
ConditionsYield
With PPA
N,N'-bis(4-methylphenyl)ethanediimidoyl dichloride
7472-70-0

N,N'-bis(4-methylphenyl)ethanediimidoyl dichloride

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With sulfuric acid
With sulfuric acid
di-p-toluidino-acetic acid ethyl ester
861524-16-5

di-p-toluidino-acetic acid ethyl ester

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With mineral acid
ethanol
64-17-5

ethanol

2-methoxy-5-methyl-indolin-3-one
861586-94-9

2-methoxy-5-methyl-indolin-3-one

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

5-methylisatin-3-oxime
13208-98-5

5-methylisatin-3-oxime

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

B

dimethyl 3-hydroxy-5-methyl-2-oxoindolin-3-ylphosphonate

dimethyl 3-hydroxy-5-methyl-2-oxoindolin-3-ylphosphonate

Conditions
ConditionsYield
With acetic acid at 100℃; for 12h;
5-methylisatin-3-oxime
13208-98-5

5-methylisatin-3-oxime

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

B

dimethyl 3-hydroxy-5-methyl-2-oxoindolin-3-ylphosphonate

dimethyl 3-hydroxy-5-methyl-2-oxoindolin-3-ylphosphonate

C

(3-Hydroxyamino-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-phosphonic acid dimethyl ester

(3-Hydroxyamino-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-phosphonic acid dimethyl ester

Conditions
ConditionsYield
With acetic acid at 100℃; for 12h;
1-p-toluenesulfonyl-5-methyl-isatin

1-p-toluenesulfonyl-5-methyl-isatin

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With sulfuric acid Darstellung;
sulfuric acid
7664-93-9

sulfuric acid

5-methyl-1-tosylindoline-2,3-dione
99448-78-9

5-methyl-1-tosylindoline-2,3-dione

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

5-methyl-isatin-p-tolylimide-(3)

5-methyl-isatin-p-tolylimide-(3)

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Conditions
ConditionsYield
With hydrogenchloride
With hydrogenchloride
3-imino-5-methyl indolin-2-one

3-imino-5-methyl indolin-2-one

acid

acid

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

7-bromo-5-methyl-2,3-dihydro-1H-indole-2,3-dione
108938-16-5

7-bromo-5-methyl-2,3-dihydro-1H-indole-2,3-dione

Conditions
ConditionsYield
With N-Bromosuccinimide at 20℃; for 24h;100%
With water; bromine
With chloroform; bromine
With bromine In acetic acid
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

6-methylquinoline-2,4-dicarboxylic acid
91493-56-0

6-methylquinoline-2,4-dicarboxylic acid

Conditions
ConditionsYield
Stage #1: 5-methyl-indole-2,3-dione; 2-oxo-propionic acid With potassium hydroxide In water at 40℃; for 12h;
Stage #2: With hydrogenchloride In water pH=3;
100%
With potassium hydroxide In water at 40℃; for 12h;100%
With potassium hydroxide In water at 40℃; for 16h; Pfitzinger Quinoline Synthesis;96%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

-CH(CH3)2 halide

-CH(CH3)2 halide

1-isopropyl-5-methylindoline-2,3-dione
620931-09-1

1-isopropyl-5-methylindoline-2,3-dione

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 20℃;100%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

-CH2CH2CH3 halide

-CH2CH2CH3 halide

5-methyl-1-propylindoline-2,3-dione
63725-87-1

5-methyl-1-propylindoline-2,3-dione

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 20℃;100%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

-CH2CH3 halide

-CH2CH3 halide

1-ethyl-5-methyl-2,3-indolinedione
299925-63-6

1-ethyl-5-methyl-2,3-indolinedione

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 20℃;100%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

-CH3 halide

-CH3 halide

1,5-dimethyl-1H-indole-2,3-dione
66440-60-6

1,5-dimethyl-1H-indole-2,3-dione

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 20℃;100%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

N-(2-bromophenyl)hydrazinecarbothioamide
25688-12-4

N-(2-bromophenyl)hydrazinecarbothioamide

5-methyl-1H-indole-2,3-dione 3-[N-(2-bromophenyl)thiosemicarbazone]
1084892-90-9

5-methyl-1H-indole-2,3-dione 3-[N-(2-bromophenyl)thiosemicarbazone]

Conditions
ConditionsYield
With sulfuric acid In ethanol for 5h; Reflux;99%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

1-bromo-hexane
111-25-1

1-bromo-hexane

1-hexyl-5-methylindoline-2,3-dione
620931-14-8

1-hexyl-5-methylindoline-2,3-dione

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 140℃; Microwave irradiation;99%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

nitromethane
75-52-5

nitromethane

3-hydroxy-5-methyl-3-(nitromethyl)-2,3-dihydro-1H-indol-2-one
1315258-63-9

3-hydroxy-5-methyl-3-(nitromethyl)-2,3-dihydro-1H-indol-2-one

Conditions
ConditionsYield
With (3ξ,8α,9R)-cinchonan-6',9-diol; benzoic acid In N,N-dimethyl acetamide at -15℃; for 3h; Henry reaction; optical yield given as %ee; enantioselective reaction;99%
With 9-O-benzyl-6'-hydroxycinchonidine In tetrahydrofuran at -30℃; for 120h; Henry reaction; optical yield given as %ee; enantioselective reaction;92%
In tetrahydrofuran at -10℃; for 11h; Henry reaction; optical yield given as %ee; enantioselective reaction;88%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

aminomalonic acid diethyl ester
6829-40-9

aminomalonic acid diethyl ester

dimethyl acetylenedicarboxylate
762-42-5

dimethyl acetylenedicarboxylate

5',5'-diethyl 3',4'-dimethyl 5-methyl-2-oxospiro[indoline-3,2'-pyrrole]-3',4',5',5'(1'H)-tetracarboxylate
1459805-65-2

5',5'-diethyl 3',4'-dimethyl 5-methyl-2-oxospiro[indoline-3,2'-pyrrole]-3',4',5',5'(1'H)-tetracarboxylate

Conditions
ConditionsYield
With trifluoroacetic acid In 1,2-dichloro-ethane at 60℃; for 36h; Time; Molecular sieve;99%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

3-amino-1-phenyl-2-pyrazolin-5-one
4149-06-8

3-amino-1-phenyl-2-pyrazolin-5-one

6-methoxy-3,4-dihydro-1(2H)-naphthalenone
1078-19-9

6-methoxy-3,4-dihydro-1(2H)-naphthalenone

3-methoxy-5'-methyl-9-phenyl-6,9,10,11-tetrahydrospiro[benzo[h]pyrazolo[3,4-b]quinoline-7,3'-indoline]-2',8(5H)-dione

3-methoxy-5'-methyl-9-phenyl-6,9,10,11-tetrahydrospiro[benzo[h]pyrazolo[3,4-b]quinoline-7,3'-indoline]-2',8(5H)-dione

Conditions
ConditionsYield
With acetic acid In water at 90℃; for 7h; Green chemistry;99%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

2,2-difluoro-2-(3-methyl-4-nitro-1,2-oxazol-5-yl)-1-phenylethan-1-one

2,2-difluoro-2-(3-methyl-4-nitro-1,2-oxazol-5-yl)-1-phenylethan-1-one

3-(difluoro(3-methyl-4-nitroisoxazol-5-yl)methyl)-3-hydroxy-5-methylindolin-2-one

3-(difluoro(3-methyl-4-nitroisoxazol-5-yl)methyl)-3-hydroxy-5-methylindolin-2-one

Conditions
ConditionsYield
With methanol; triethylamine at 20℃; for 24h;99%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

Dimethyl phosphite
868-85-9

Dimethyl phosphite

dimethyl 3-hydroxy-5-methyl-2-oxoindolin-3-ylphosphonate

dimethyl 3-hydroxy-5-methyl-2-oxoindolin-3-ylphosphonate

Conditions
ConditionsYield
With phosphotungstic acid supported on silica-coated magnetic Fe3O4 nanoparticle In neat (no solvent) at 80℃; for 16h; Kabachnik-Fields Reaction; Green chemistry;98%
With magnetic nanoparticle γ-Fe2O3-immobilized 1,5,7-triazabicyclo[4.4.0]dec-5-ene In neat (no solvent) at 60℃; for 5h;91%
at 100℃; for 6h;80%
With β‐cyclodextrin In methanol; water at 20℃;
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethyl 3-hydroxy-5-methyl-2-oxoindolin-3-ylphosphonate

diethyl 3-hydroxy-5-methyl-2-oxoindolin-3-ylphosphonate

Conditions
ConditionsYield
With phosphotungstic acid supported on silica-coated magnetic Fe3O4 nanoparticle In neat (no solvent) at 80℃; for 16h; Kabachnik-Fields Reaction; Green chemistry;98%
With zinc(II) oxide In neat (no solvent) at 20℃; for 0.666667h;94%
With magnetic nanoparticle γ-Fe2O3-immobilized 1,5,7-triazabicyclo[4.4.0]dec-5-ene In neat (no solvent) at 60℃; for 6h;91%
at 100℃; for 6h;80%
With β‐cyclodextrin In methanol; water at 20℃;
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

4-methoxy-aniline
104-94-9

4-methoxy-aniline

3-(4-methoxy-phenylimino)-5-methyl-1,3-dihydro-indol-2-one

3-(4-methoxy-phenylimino)-5-methyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
In water at 20℃; for 4h;98%
In ethanol Heating;72%
With acetic acid In ethanol for 0.75h; Reflux;
With acetic acid at 20℃; for 2h;
In ethanol for 2h; Reflux;
indole
120-72-9

indole

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

5'-methyl-1H,1''H-3,3':3',3''-terindol-2'(1'H)-one

5'-methyl-1H,1''H-3,3':3',3''-terindol-2'(1'H)-one

Conditions
ConditionsYield
With 60 wtpercent phosphotungstic acid supported on MCM-41 In tetrahydrofuran at 20℃; for 2.5h; Friedel-Crafts Acylation;98%
With 1‐(2‐hydroxyethyl)‐1,4‐diazabicyclo[2.2.2]octanylium tetrachloroferrate In ethanol at 50℃; for 0.0833333h; Green chemistry;98%
With boron trifluoride supported on nano-SiO2 In methanol for 0.45h; Reflux;95%
2-{[5-(4-methoxyphenyl)-1,3,5-oxadiazol-2-yl]imino}-4-thiazolidinone
89335-21-7

2-{[5-(4-methoxyphenyl)-1,3,5-oxadiazol-2-yl]imino}-4-thiazolidinone

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

3-[2-[(E)-5-(4-Methoxy-phenyl)-[1,3,4]oxadiazol-2-ylimino]-4-oxo-thiazolidin-(5Z)-ylidene]-5-methyl-1,3-dihydro-indol-2-one

3-[2-[(E)-5-(4-Methoxy-phenyl)-[1,3,4]oxadiazol-2-ylimino]-4-oxo-thiazolidin-(5Z)-ylidene]-5-methyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With sodium acetate; acetic anhydride In acetic acid at 150 - 160℃; for 5h;98%
2-Amino-6-((E)-nonadec-10-enyl)-benzoic acid
934273-34-4

2-Amino-6-((E)-nonadec-10-enyl)-benzoic acid

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

C35H48N2O3

C35H48N2O3

Conditions
ConditionsYield
for 0.0666667h; microwave irradiation;98%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

ethane-1,2-dithiol
540-63-6

ethane-1,2-dithiol

5'-methylspiro[[1,3]dithiolane-2,3'-indolin]-2'-one

5'-methylspiro[[1,3]dithiolane-2,3'-indolin]-2'-one

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In acetic acid at 20 - 60℃; for 0.75h;98%
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 16h;62%
With boron trifluoride diethyl etherate; acetic acid at 60℃;
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

2-Hydroxy-1,4-naphthoquinone
83-72-7

2-Hydroxy-1,4-naphthoquinone

malononitrile
109-77-3

malononitrile

2-amino-5'-methyl-2',5,10-trioxo-5,10-dihydrospiro[benzo[g]chromene-4,3'-indoline]-3-carbonitrile
1204748-04-8

2-amino-5'-methyl-2',5,10-trioxo-5,10-dihydrospiro[benzo[g]chromene-4,3'-indoline]-3-carbonitrile

Conditions
ConditionsYield
With toluene-4-sulfonic acid In water for 3h; Reflux;98%
With graphene oxide-supported dicationic ionic liquid In water for 0.333333h; Reflux; Green chemistry;95%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

edaravone
89-25-8

edaravone

malononitrile
109-77-3

malononitrile

6'-amino-3',5'-dimethyl-2-oxo-1'-phenyl-1'H-spiro[indoline-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile
380432-38-2

6'-amino-3',5'-dimethyl-2-oxo-1'-phenyl-1'H-spiro[indoline-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile

Conditions
ConditionsYield
With sodium chloride In water at 20℃; for 0.166667h; Sonication;98%
With ammonium cerium (IV) nitrate In water at 20℃; for 0.166667h; Sonication; Green chemistry;98%
With ZnS nanoparticles In water at 20℃; for 0.2h; ultrasonic irradiation;97%
In water at 60℃; for 1h;92%
With silica immobilized propyl imidazolium chloride In water for 0.5h; Reflux;88%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one
83-07-8

4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one

2-mercaptopropanoic acid
79-42-5

2-mercaptopropanoic acid

3'-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-5,5'-dimethyl-spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)-dione

3'-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-5,5'-dimethyl-spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)-dione

Conditions
ConditionsYield
With cetyltrimethylammonim bromide In water Sonication; Combinatorial reaction / High throughput screening (HTS);98%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

2-methyl-3-bromo-1-propene
1458-98-6

2-methyl-3-bromo-1-propene

3-(2-methylallyl)-3-hydroxy-5-methyl-1,3-dihydro-2H-indol-2-one
1342300-25-7

3-(2-methylallyl)-3-hydroxy-5-methyl-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
With indium In decaethylene glycol at 20℃; for 0.25h; Barbier reaction;98%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

allyl bromide
106-95-6

allyl bromide

3-allyl-3-hydroxy-5-methyl-1,3-dihydro-2H-indol-2-one
1309578-03-7

3-allyl-3-hydroxy-5-methyl-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
With indium In decaethylene glycol at 20℃; for 0.166667h; Barbier reaction;98%
1,3-benzothiazol-6-amine
533-30-2

1,3-benzothiazol-6-amine

5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

3-(benzothiazol-6-ylimino)-1,3-dihydro-5-methyl-2H-indole-2-one
1391950-07-4

3-(benzothiazol-6-ylimino)-1,3-dihydro-5-methyl-2H-indole-2-one

Conditions
ConditionsYield
In water at 20℃; for 3h;98%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

3-phenyl-1-(1H-pyrazol-1-yl)but-3-en-1-one

3-phenyl-1-(1H-pyrazol-1-yl)but-3-en-1-one

(S)-5-methyl-4'-phenylspiro[indoline-3,2'-pyran]-2,6'(3'H)-dione

(S)-5-methyl-4'-phenylspiro[indoline-3,2'-pyran]-2,6'(3'H)-dione

Conditions
ConditionsYield
With 1-[3,5-bis(trifluoromethyl)phenyl]-3-[(1S,2S)-2-(dimethylamino)cyclohexyl]thiourea In acetonitrile at 25℃; for 24h; enantioselective reaction;98%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

ethyl acetoacetate
141-97-9

ethyl acetoacetate

3,3-bis(3-hydroxy-5-methyl-1H-pyrazol-4-yl)-5-methylindolin-2-one

3,3-bis(3-hydroxy-5-methyl-1H-pyrazol-4-yl)-5-methylindolin-2-one

Conditions
ConditionsYield
Stage #1: ethyl acetoacetate With hydrazine hydrate for 0.0833333h;
Stage #2: 5-methyl-indole-2,3-dione With sodium hydrogencarbonate In ethanol at 78℃; for 18h;
98%
5-methyl-indole-2,3-dione
608-05-9

5-methyl-indole-2,3-dione

3-amino-1-phenyl-2-pyrazolin-5-one
4149-06-8

3-amino-1-phenyl-2-pyrazolin-5-one

inden-1-one
83-33-0

inden-1-one

5'-methyl-2-phenyl-1,2,5,10-tetrahydro-3H-spiro[indeno[1,2-b]pyrazolo[4,3-e]pyridine-4,3'-indoline]-2',3-dione

5'-methyl-2-phenyl-1,2,5,10-tetrahydro-3H-spiro[indeno[1,2-b]pyrazolo[4,3-e]pyridine-4,3'-indoline]-2',3-dione

Conditions
ConditionsYield
With acetic acid In water at 90℃; for 7h; Green chemistry;98%

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