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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

5-Nitrouracil

Cas:611-08-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Nitrouracil supplier in China

Cas:611-08-5

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Jinan Finer Chemical Co., Ltd

Product description: Product name 5-Nitrouracil CAS number 611-08-5 Assay ≥99% Appearance Off-white solid Capacity 200mt/year Application Pharmaceutical intermediate

5-Nitrouracil

Cas:611-08-5

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-nitrouracil

Cas:611-08-5

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 611-08-5 5-Nitrouracil Manufacturer

Cas:611-08-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Nitrouracil

Cas:611-08-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

D - glucuronic acid and N - acetyl glucosamine disaccharides unit composed of hyaluronic acid (Hyaluronan), also called uronic acid, hyaluronic acid, basic structure is made up of two disaccharides unit D - glucuronic acid and N - acetyl glucosamin

5-Nitrouracil

Cas:611-08-5

Min.Order:1000 Gram

FOB Price: $500.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

tianuf-chem_ 5-Nitrouracil,611-08-5

Cas:611-08-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 611-08-5 with fast shipping

Cas:611-08-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name:5-Nitrouracil CAS No.:611-08-5 EINECS: 210-250-4 Molecular Formula: C4H3N3O4 Molecular Weight: 157.08 Appearance:White Powder Appearance: white

5-Nitrouracil

Cas:611-08-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-Nitrouracil 611-08-5

Cas:611-08-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Nitrouracil

Cas:611-08-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:611-08-5

Cas:611-08-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

5-Nitrouracil

Cas:611-08-5

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Nitrouracil

Cas:611-08-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

5-Nitrouracil

Cas:611-08-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-Nitrouracil

Cas:611-08-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

5-NITROURACIL

Cas:611-08-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Nitrouracil

Cas:611-08-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

5-Nitrouracil

Cas:611-08-5

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

5-Nitrouracil Manufacturer/High quality/Best price/In stock

Cas:611-08-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2,4-Dihydroxy-5-nitropyrimidine

Cas:611-08-5

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

5-Nitrouracil

Cas:611-08-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

5-Nitrouracil

Cas:611-08-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

5-Nitrouracil

Cas:611-08-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

5-Nitrouracil

Cas:611-08-5

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

5-Nitrouracil

Cas:611-08-5

Min.Order:0

Negotiable

Type:Other

inquiry

Wuhu Nuowei Chemistry Technologies Co., Ltd.

Wuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma

5-Nitrouracil

Cas:611-08-5

Min.Order:100 Gram

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

5-Nitrouracil

Cas:611-08-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/5-Nitrouracil

Cas:611-08-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

uracil
66-22-8

uracil

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
With sulfuric acid; nitric acid at 50 - 55℃; for 3h; Inert atmosphere;92%
With sulfuric acid; nitric acid at 125℃;
With nitric acid
benzoin oxime
441-38-3

benzoin oxime

A

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

B

benzaldehyde
100-52-7

benzaldehyde

C

benzonitrile
100-47-0

benzonitrile

Conditions
ConditionsYield
With triethylamine; 2,4-Dichloro-5-nitropyrimidine In acetonitrile for 5h; Product distribution; Heating;A n/a
B 65%
C 50%
Benzophenone oxime
574-66-3

Benzophenone oxime

2,4-Dichloro-5-nitropyrimidine
49845-33-2

2,4-Dichloro-5-nitropyrimidine

A

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

B

2,4-bis-diphenyliminoxy-5-nitropyrimidine

2,4-bis-diphenyliminoxy-5-nitropyrimidine

Conditions
ConditionsYield
In dichloromethane for 0.5h; Product distribution; Ambient temperature; other solvent, temperature, reaction time;A 42%
B 44%
6-Methyluracil
626-48-2

6-Methyluracil

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
With sulfuric acid; nitric acid
4-chloro-2-ethylsulfanyl-pyrimidine
98198-74-4

4-chloro-2-ethylsulfanyl-pyrimidine

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
With sulfuric acid; nitric acid
2-ethylthio-3H-pyrimidin-4-one
6965-19-1

2-ethylthio-3H-pyrimidin-4-one

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
With sulfuric acid; nitric acid
5-nitroorotic acid
17687-24-0

5-nitroorotic acid

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
at 100 - 150℃;
at 130℃; das saure Kaliumsalz reagiert;
4-hydroxy-2-mercaptopyrimidine
141-90-2

4-hydroxy-2-mercaptopyrimidine

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
With nitric acid
para-dinitrobenzene
100-25-4

para-dinitrobenzene

5-nitrouracil (radical anion)
58431-12-2

5-nitrouracil (radical anion)

A

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

B

1,4-dinitroanthracene radical anion
100-25-4

1,4-dinitroanthracene radical anion

Conditions
ConditionsYield
In water; isopropyl alcohol Rate constant; Thermodynamic data; Irradiation; electron transfer reaction ΔE exc.;
(4-nitrophenyl)ethanone
100-19-6

(4-nitrophenyl)ethanone

5-nitrouracil (radical anion)
58431-12-2

5-nitrouracil (radical anion)

A

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

B

p-nitroacetophenone anion radical
100-19-6

p-nitroacetophenone anion radical

Conditions
ConditionsYield
In water; isopropyl alcohol Rate constant; Thermodynamic data; Irradiation; electron transfer reaction ΔE exc.;
2,4-Dichloro-5-nitropyrimidine
49845-33-2

2,4-Dichloro-5-nitropyrimidine

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
With benzoic acid In acetonitrile for 0.166667h; Product distribution; Ambient temperature; other reagents, reaction time, temperature, solvent;
1-nitrouracil

1-nitrouracil

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
at 150℃;
2-amino-5-nitropyrimidin-4(3H)-one
7254-29-7

2-amino-5-nitropyrimidin-4(3H)-one

sulfuric acid
7664-93-9

sulfuric acid

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
at 190 - 200℃;
4-amino-5-nitropyrimidin-2(1H)-one
69099-99-6

4-amino-5-nitropyrimidin-2(1H)-one

sulfuric acid
7664-93-9

sulfuric acid

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
at 185 - 200℃; im Rohr;
5-nitroorotic acid
17687-24-0

5-nitroorotic acid

water
7732-18-5

water

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

2-thiouracil
141-90-2

2-thiouracil

nitric acid
7697-37-2

nitric acid

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

5-nitro-uracil-carboxylic acid-(4)

5-nitro-uracil-carboxylic acid-(4)

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
at 150℃;
With water
acidic potassium salt of/the/ 5-nitro-uracil-carboxylic acid-(4)

acidic potassium salt of/the/ 5-nitro-uracil-carboxylic acid-(4)

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
at 130 - 170℃;
anhydronitrouridinecarboxylic acid

anhydronitrouridinecarboxylic acid

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Conditions
ConditionsYield
With sulfuric acid at 130 - 135℃; im Rohr;
6-Methyluracil
626-48-2

6-Methyluracil

HNO3+H2SO4

HNO3+H2SO4

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

4-chloro-2-ethylsulfanyl-pyrimidine
98198-74-4

4-chloro-2-ethylsulfanyl-pyrimidine

HNO3+H2SO4

HNO3+H2SO4

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

2-ethylthio-3H-pyrimidin-4-one
6965-19-1

2-ethylthio-3H-pyrimidin-4-one

HNO3+H2SO4

HNO3+H2SO4

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

uracil
66-22-8

uracil

HNO3

HNO3

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-nitropyrimidine-2,4(1H,3H)-dione
3106-01-2

1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-nitropyrimidine-2,4(1H,3H)-dione

A

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

B

2-deoxy–α-D-ribose 1-phosphate
17039-17-7

2-deoxy–α-D-ribose 1-phosphate

Conditions
ConditionsYield
With thymidine phosphorylase; 5-fluoro-6-[(2-aminoimidazol-1-yl)methyl]uracil; hydrogenphosphate Kinetics; Concentration; Reagent/catalyst; Enzymatic reaction;
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

methyl bromide
74-83-9

methyl bromide

1,3-dimethyl-5-nitrouracil
41613-26-7

1,3-dimethyl-5-nitrouracil

Conditions
ConditionsYield
With sodium hydroxide; tetrabutylammomium bromide In dichloromethane at 20℃; for 24h;100%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

1,8-diazabicyclo[5.4.0]undec-7-ene
6674-22-2

1,8-diazabicyclo[5.4.0]undec-7-ene

5-nitro-1H-pyrimidine-2,4-dione; compound with 2,3,4,6,7,8,9,10-octahydro-pyrimido[1,2-a]azepine

5-nitro-1H-pyrimidine-2,4-dione; compound with 2,3,4,6,7,8,9,10-octahydro-pyrimido[1,2-a]azepine

Conditions
ConditionsYield
In acetonitrile at 20℃;97%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

8-amino quinoline
578-66-5

8-amino quinoline

copper(II) acetate monohydrate
6046-93-1

copper(II) acetate monohydrate

C13H10CuN5O4(1+)

C13H10CuN5O4(1+)

Conditions
ConditionsYield
Stage #1: 8-amino quinoline; copper(II) acetate monohydrate In methanol at 70℃; for 0.75h;
Stage #2: 5-nitrobarbituric acid In methanol at 70℃; for 1h;
94.9%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

2,4-Dichloro-5-nitropyrimidine
49845-33-2

2,4-Dichloro-5-nitropyrimidine

Conditions
ConditionsYield
With trichlorophosphate In N,N-dimethyl-aniline at 110℃; for 8h;94%
With N,N-dimethyl-aniline; trichlorophosphate Reflux;74%
With N-ethyl-N,N-diisopropylamine; trichlorophosphate at 0 - 25℃;70%
glycidyl methyl ether
930-37-0

glycidyl methyl ether

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

1-(2-hydroxy-3-methoxypropyl)-5-nitrouracil

1-(2-hydroxy-3-methoxypropyl)-5-nitrouracil

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide Heating;89%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Bromodiphenylmethane
776-74-9

Bromodiphenylmethane

1-benzhydryl-5-nitropyrimidine-2,4(1H,3H)-dione

1-benzhydryl-5-nitropyrimidine-2,4(1H,3H)-dione

Conditions
ConditionsYield
With N,O-bis-(trimethylsilyl)-acetamide; iodine In acetonitrile for 3.5h; Reflux;84.5%
With N,O-bis-(trimethylsilyl)-acetamide; iodine In acetonitrile at 20℃; for 24h;77%
Stage #1: 5-nitrobarbituric acid With N,O-bis-(trimethylsilyl)-acetamide In acetonitrile at 20℃;
Stage #2: Bromodiphenylmethane With iodine In acetonitrile Heating;
72%
pyridine
110-86-1

pyridine

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

trimethyl phosphite
512-56-1

trimethyl phosphite

C6H8N(1+)*C4H3N3O4*C2H6O4P(1-)
126118-81-8

C6H8N(1+)*C4H3N3O4*C2H6O4P(1-)

Conditions
ConditionsYield
for 5h; Heating;82%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Phenyl glycidyl ether
122-60-1

Phenyl glycidyl ether

A

1-(2-hydroxy-3-phenoxypropyl)pyrimidine-5-nitro-2,4(1H,3H)-dione

1-(2-hydroxy-3-phenoxypropyl)pyrimidine-5-nitro-2,4(1H,3H)-dione

B

1,3-bis(2-hydroxy-3-phenoxypropyl)pyrimidine-5-nitro-2,4(1H,3H)-dione

1,3-bis(2-hydroxy-3-phenoxypropyl)pyrimidine-5-nitro-2,4(1H,3H)-dione

Conditions
ConditionsYield
With tetrabutylammomium bromide; magnesium oxide at 170℃; for 0.0166667h; microwave irradiation;A 82%
B 15%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

3-(4-chlorophenoxy)-1-propanol
18673-04-6

3-(4-chlorophenoxy)-1-propanol

1-(3-(4-chlorophenoxy) propyl)-5-nitropyrimidine-2,4 (1H, 3H)-dione
1198085-46-9

1-(3-(4-chlorophenoxy) propyl)-5-nitropyrimidine-2,4 (1H, 3H)-dione

Conditions
ConditionsYield
With iodine; potassium carbonate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide for 10h; Reflux; regioselective reaction;82%
With potassium carbonate; 1-n-butyl-3-methylimidazolim bromide; triethylamine; p-toluenesulfonyl chloride at 80℃; for 11h; Green chemistry;71%
With tetrachloromethane; tetra-(n-butyl)ammonium iodide; potassium carbonate; triphenylphosphine In N,N-dimethyl-formamide for 10h; Reflux;68%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

5-Aminouracil
932-52-5

5-Aminouracil

Conditions
ConditionsYield
With ammonia at 75℃; for 3h; pH=8; Inert atmosphere;81%
With aluminium amalgam; ammonia
With hydrogenchloride; tin
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

butan-1-ol
71-36-3

butan-1-ol

1-butyl-5-nitropyrimidine-2,4(1H,3H)-dione
28485-13-4

1-butyl-5-nitropyrimidine-2,4(1H,3H)-dione

Conditions
ConditionsYield
With tetrachloromethane; tetra-(n-butyl)ammonium iodide; potassium carbonate; triphenylphosphine In N,N-dimethyl-formamide for 10h; Reflux;81%
With potassium carbonate; triethylamine In N,N-dimethyl-formamide for 10h; Heating;76%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

methyl iodide
74-88-4

methyl iodide

1,3-dimethyl-5-nitrouracil
41613-26-7

1,3-dimethyl-5-nitrouracil

Conditions
ConditionsYield
Stage #1: 5-nitrobarbituric acid With sodium hydride In N,N-dimethyl-formamide at 0℃; for 2h;
Stage #2: methyl iodide In N,N-dimethyl-formamide at 25℃; for 20h;
81%
With sodium hydride In N,N-dimethyl-formamide for 4h; Cooling with ice; Inert atmosphere;
Stage #1: 5-nitrobarbituric acid With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 20h; Inert atmosphere;
Stage #2: methyl iodide In N,N-dimethyl-formamide; mineral oil at 20℃; Inert atmosphere;
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

methyl iodide
74-88-4

methyl iodide

A

1-methyl-5-nitrouracil
28495-88-7

1-methyl-5-nitrouracil

B

1,3-dimethyl-5-nitrouracil
41613-26-7

1,3-dimethyl-5-nitrouracil

C

3-methyl-5-nitro-2,4(1H,3H)pyrimidinedione
25912-37-2

3-methyl-5-nitro-2,4(1H,3H)pyrimidinedione

Conditions
ConditionsYield
With tetra(n-butyl)ammonium hydroxide In methanol; acetonitrile at 40℃; for 72h;A 80%
B n/a
C n/a
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

ethyl acrylate
140-88-5

ethyl acrylate

3-(5-nitro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)propionic acid ethyl ester
2950-88-1

3-(5-nitro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)propionic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 60℃; Aza-Micheal reaction;79%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

methyl iodide
74-88-4

methyl iodide

1-methyl-5-nitrouracil
28495-88-7

1-methyl-5-nitrouracil

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide77%
With sodium hydroxide; potassium carbonate In N-methyl-acetamide; water77%
With sodium hydroxide; potassium carbonate In N-methyl-acetamide; water77%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

acrylic acid n-butyl ester
141-32-2

acrylic acid n-butyl ester

3-(5-nitro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)propionic acid butyl ester
1370413-79-8

3-(5-nitro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)propionic acid butyl ester

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 60℃; Aza-Micheal reaction;75%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

Thiotepa
52-24-4

Thiotepa

N,N',N''-Tris<β-(5-nitro-3-uracil)ethyl>thiophosphoric acid triamide
84295-07-8

N,N',N''-Tris<β-(5-nitro-3-uracil)ethyl>thiophosphoric acid triamide

Conditions
ConditionsYield
In water at 37℃; for 288h;74.2%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

3-(3,4-dihydro-5-nitro-2,4-dioxo-(2H)pyrimidin-1-yl)propanoic acid methyl ester
918968-22-6

3-(3,4-dihydro-5-nitro-2,4-dioxo-(2H)pyrimidin-1-yl)propanoic acid methyl ester

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 60℃; Aza-Micheal reaction;71%
In N,N-dimethyl-formamide at 20℃; Michael-type addition; regioselective reaction;54%
With triethylamine In N,N-dimethyl-formamide at 20℃; for 24h; Michael condensation;
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

trimethyl phosphite
512-56-1

trimethyl phosphite

1-methyl-5-nitrouracil
28495-88-7

1-methyl-5-nitrouracil

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 5h; Heating;70%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

8-amino quinoline
578-66-5

8-amino quinoline

copper(II) acetate monohydrate
6046-93-1

copper(II) acetate monohydrate

C13H10N5NiO4(1+)

C13H10N5NiO4(1+)

Conditions
ConditionsYield
Stage #1: 8-amino quinoline; copper(II) acetate monohydrate In methanol at 70℃; for 0.75h;
Stage #2: 5-nitrobarbituric acid In methanol at 70℃; for 1h;
68.2%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

sodium diphenyl phosphate
3279-55-8

sodium diphenyl phosphate

C12H10O4P(1-)*C4H3N3O4*Na(1+)
126118-86-3

C12H10O4P(1-)*C4H3N3O4*Na(1+)

Conditions
ConditionsYield
In N,N-dimethyl-formamide Heating;56%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

1,1,1-trifluoro-2-bromo-2-chloroethane
151-67-7

1,1,1-trifluoro-2-bromo-2-chloroethane

C10H4BrClN6O8

C10H4BrClN6O8

Conditions
ConditionsYield
With potassium hydroxide; dibenzo-18-crown-6 In N,N-dimethyl-formamide; benzene at 80 - 90℃; Substitution;53.2%
piperidine
110-89-4

piperidine

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

5-nitro-2,4-di(piperidin-1-yl)pyrimidine

5-nitro-2,4-di(piperidin-1-yl)pyrimidine

Conditions
ConditionsYield
With copper acetylacetonate; di-tert-butyl peroxide; N,N-dimethyl-formamide at 100℃; for 10h; Green chemistry;53%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

phosphorisocyanatidic acid dimethyl ester
867-04-9

phosphorisocyanatidic acid dimethyl ester

[3-(Dimethoxy-phosphorylaminocarbonyl)-5-nitro-2,6-dioxo-3,6-dihydro-2H-pyrimidine-1-carbonyl]-phosphoramidic acid dimethyl ester

[3-(Dimethoxy-phosphorylaminocarbonyl)-5-nitro-2,6-dioxo-3,6-dihydro-2H-pyrimidine-1-carbonyl]-phosphoramidic acid dimethyl ester

Conditions
ConditionsYield
at 170 - 200℃; for 12h;52.5%
piperidine
110-89-4

piperidine

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

formaldehyd
50-00-0

formaldehyd

N-3-Piperidinomethylene-5-nitrouracil
75682-16-5

N-3-Piperidinomethylene-5-nitrouracil

Conditions
ConditionsYield
In methanol; water for 48h; Ambient temperature;51.1%
morpholine
110-91-8

morpholine

5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

formaldehyd
50-00-0

formaldehyd

N-3-Morpholinomethylene-5-nitrouracil
75682-15-4

N-3-Morpholinomethylene-5-nitrouracil

Conditions
ConditionsYield
In methanol; water for 48h; Ambient temperature;45.3%
5-nitrobarbituric acid
611-08-5

5-nitrobarbituric acid

1,5-dibromo-pentane
111-24-0

1,5-dibromo-pentane

1,3-bis(5-bromopentyl)-5-nitro-1,2,3,4-tetrahydropyrimidine-2,4-dione
1131732-36-9

1,3-bis(5-bromopentyl)-5-nitro-1,2,3,4-tetrahydropyrimidine-2,4-dione

Conditions
ConditionsYield
Stage #1: 5-nitrobarbituric acid With sodium butanolate In iso-butanol for 20h; Reflux;
Stage #2: 1,5-dibromo-pentane In N,N-dimethyl-formamide at 50 - 60℃;
43%

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