Items Standard Result Appearance White powder Conforms Assay ≥98% 99.5%
Cas:6559-91-7
Min.Order:1 Gram
FOB Price: $100.0 / 500.0
Type:Trading Company
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:6559-91-7
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiryhigh quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
Cas:6559-91-7
Min.Order:1 Kilogram
Negotiable
Type:Manufacturers
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:6559-91-7
Min.Order:1
Negotiable
Type:Other
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:6559-91-7
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryCangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi
Cas:6559-91-7
Min.Order:1 Kilogram
FOB Price: $5.0
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:6559-91-7
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:6559-91-7
Min.Order:1 Kilogram
FOB Price: $100.0 / 150.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:6559-91-7
Min.Order:10 Gram
FOB Price: $146.0 / 176.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:6559-91-7
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry4'-Demethylepipodophyllotoxin CAS:6559-91-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality
Cas:6559-91-7
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:6559-91-7
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:6559-91-7
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryProduct Name: 4-Demethylepipodophyllotoxin Synonyms: (5R)-5,8,8aβ,9-Tetrahydro-9α-hydroxy-5β-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aαH)-one;(5R)-5β-(3,5-Dimethoxy-4-hydroxyp
Cas:6559-91-7
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Cas:6559-91-7
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryChengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medic
Cas:6559-91-7
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:6559-91-7
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:6559-91-7
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryHigh purity 4'-Demethylepipodophyllotoxin 6559-91-7 in stock immediately delivery good supplierAppearance:Powder Storage:Dry and ventilated Package:according to customers' requirements Application:APIs Transportation:By air(EMS or EUB or FedEx or TNT
Cas:6559-91-7
Min.Order:1 Gram
Negotiable
Type:Other
inquiryOur company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so
Cas:6559-91-7
Min.Order:1 Metric Ton
FOB Price: $500.0
Type:Lab/Research institutions
inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:6559-91-7
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:6559-91-7
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:6559-91-7
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:6559-91-7
Min.Order:1 Metric Ton
FOB Price: $1.5
Type:Trading Company
inquiryLocated in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h
Cas:6559-91-7
Min.Order:0
Negotiable
Type:Other
inquiryWuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma
SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe
Cas:6559-91-7
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryThe quality is guaranteed. If you find the product is wrong compared with COA, we promise 100% refund or change product. COA and HPLC will be shipped out with goods. You can also inform your analysis method and we will follow your analysis me
Cas:6559-91-7
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiryGOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
Conditions | Yield |
---|---|
With methanesulfonic acid; DL-methionine; trifluoroacetic acid at 40℃; for 0.75h; | 93% |
Stage #1: podofilox With methanesulfonic acid; sodium iodide In dichloromethane at 0 - 20℃; for 5h; Stage #2: With barium carbonate In water; acetone at 40℃; for 0.5h; | 90% |
Stage #1: podofilox With 1-(Trimethylsilyl)imidazole In dichloromethane at 0℃; Stage #2: With water; barium carbonate In acetone | 79% |
Carbonic acid benzyl ester 4-((5R,5aR,8aR)-6,9-dioxo-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl)-2,6-dimethoxy-phenyl ester
4'-demethylepipodophyllotoxin
Conditions | Yield |
---|---|
With ruthenium(II) chloride; (S)-N2,N2'-bis(pyridin-2-ylmethyl-1,1'-binaphthyl-2,2'-diamine); hydrogen In isopropyl alcohol at 20 - 25℃; under 38002.6 Torr; for 18h; | 89% |
4'-O-demethyl-4β-bromo-4-desoxypodophyllotoxin
4'-demethylepipodophyllotoxin
Conditions | Yield |
---|---|
With water; barium carbonate In acetone at 40℃; for 4h; | 71% |
With barium carbonate In water; acetone for 1h; Heating; | 52% |
acetic acid
podofilox
A
4'-demethylepipodophyllotoxin
B
4'-demethyl-β-apopicropodophyllotoxin
C
4'-demethyl-1-O-ethyl-1-epipodophyllotoxin
D
epipodophyllotoxin
Conditions | Yield |
---|---|
With hydrogen bromide 1.) 15 min, 2.) RT, 20 h; Multistep reaction. Further byproducts given; |
acetic acid
podofilox
A
4'-demethylepipodophyllotoxin
B
4'-demethyl-β-apopicropodophyllotoxin
C
3',4'-didemethylepipodophyllotoxin
D
epipodophyllotoxin
Conditions | Yield |
---|---|
With hydrogen bromide 1.) 15 min, 2.) RT, 20 h; Multistep reaction. Further byproducts given; |
etoposide
4'-demethylepipodophyllotoxin
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sodium iodide; chloro-trimethyl-silane / acetonitrile / 0 °C 2: water; barium carbonate / acetone / 20 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1.1: sodium hydroxide / tetrahydrofuran / 25 - 30 °C 2.1: lithium diisopropyl amide / tetrahydrofuran / 3 h / -20 - -15 °C / Inert atmosphere 3.1: iron(III) chloride / dichloromethane / 1 h / 18 - 22 °C 4.1: triethylamine / dichloromethane / 1 h / -2 - 2 °C 5.1: palladium diacetate; triphenylphosphine; potassium carbonate / acetonitrile / 20 h / 75 - 85 °C 6.1: pyridine; ozone / dichloromethane; methanol / 5 h / -25 - -15 °C 6.2: 4 h / 20 °C / Inert atmosphere 7.1: (S)-N2,N2'-bis(pyridin-2-ylmethyl-1,1'-binaphthyl-2,2'-diamine); ruthenium(II) chloride; hydrogen / isopropyl alcohol / 18 h / 20 - 25 °C / 38002.6 Torr View Scheme |
4'-demethylepipodophyllotoxin
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1.1: lithium diisopropyl amide / tetrahydrofuran / 3 h / -20 - -15 °C / Inert atmosphere 2.1: iron(III) chloride / dichloromethane / 1 h / 18 - 22 °C 3.1: triethylamine / dichloromethane / 1 h / -2 - 2 °C 4.1: palladium diacetate; triphenylphosphine; potassium carbonate / acetonitrile / 20 h / 75 - 85 °C 5.1: pyridine; ozone / dichloromethane; methanol / 5 h / -25 - -15 °C 5.2: 4 h / 20 °C / Inert atmosphere 6.1: (S)-N2,N2'-bis(pyridin-2-ylmethyl-1,1'-binaphthyl-2,2'-diamine); ruthenium(II) chloride; hydrogen / isopropyl alcohol / 18 h / 20 - 25 °C / 38002.6 Torr View Scheme |
4'-demethylepipodophyllotoxin
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: iron(III) chloride / dichloromethane / 1 h / 18 - 22 °C 2.1: triethylamine / dichloromethane / 1 h / -2 - 2 °C 3.1: palladium diacetate; triphenylphosphine; potassium carbonate / acetonitrile / 20 h / 75 - 85 °C 4.1: pyridine; ozone / dichloromethane; methanol / 5 h / -25 - -15 °C 4.2: 4 h / 20 °C / Inert atmosphere 5.1: (S)-N2,N2'-bis(pyridin-2-ylmethyl-1,1'-binaphthyl-2,2'-diamine); ruthenium(II) chloride; hydrogen / isopropyl alcohol / 18 h / 20 - 25 °C / 38002.6 Torr View Scheme |
4'-demethylepipodophyllotoxin
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: triethylamine / dichloromethane / 1 h / -2 - 2 °C 2.1: palladium diacetate; triphenylphosphine; potassium carbonate / acetonitrile / 20 h / 75 - 85 °C 3.1: pyridine; ozone / dichloromethane; methanol / 5 h / -25 - -15 °C 3.2: 4 h / 20 °C / Inert atmosphere 4.1: (S)-N2,N2'-bis(pyridin-2-ylmethyl-1,1'-binaphthyl-2,2'-diamine); ruthenium(II) chloride; hydrogen / isopropyl alcohol / 18 h / 20 - 25 °C / 38002.6 Torr View Scheme |
4'-demethylepipodophyllotoxin
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: palladium diacetate; triphenylphosphine; potassium carbonate / acetonitrile / 20 h / 75 - 85 °C 2.1: pyridine; ozone / dichloromethane; methanol / 5 h / -25 - -15 °C 2.2: 4 h / 20 °C / Inert atmosphere 3.1: (S)-N2,N2'-bis(pyridin-2-ylmethyl-1,1'-binaphthyl-2,2'-diamine); ruthenium(II) chloride; hydrogen / isopropyl alcohol / 18 h / 20 - 25 °C / 38002.6 Torr View Scheme |
4'-demethylepipodophyllotoxin
4β-azido-4-deoxy-4′-demethylepipodophyllotoxin
Conditions | Yield |
---|---|
With sodium azide; trifluoroacetic acid In chloroform at 20℃; | 100% |
With sodium azide; trifluoroacetic acid In chloroform for 0.25h; | 94% |
With sodium azide; trifluoroacetic acid In chloroform at 20℃; Cooling with ice; | 91.8% |
4'-demethylepipodophyllotoxin
tert-butyldimethylsilyl chloride
4,4'-bis-O-(dimethyl-tert-butylsilyl)-4'-O-demethylepipodophyllotoxin
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide for 20h; | 98% |
With 2,6-dimethylpyridine In dichloromethane at 0℃; for 1h; | 81% |
4'-demethylepipodophyllotoxin
acetic acid
4'-demethylepipodophyllotoxin diacetate
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; | 98% |
4'-demethylepipodophyllotoxin
benzyl chloroformate
4'-demethyl-4'-O-(benzoyloxycarbonyl)epipodophyllotoxin
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0℃; for 2h; | 97% |
With triethylamine In dichloromethane at 0 - 35℃; for 2h; | 97% |
With triethylamine In dichloromethane at 0 - 35℃; for 2h; | 97% |
Conditions | Yield |
---|---|
sulfuric acid at 20℃; for 3h; Ritter Reaction; | 96% |
4'-demethylepipodophyllotoxin
chloroacetonitrile
4-chloroacetamido-4-deoxy-4'-demethylepipodophyllotoxin
Conditions | Yield |
---|---|
With sulfuric acid In isopropyl alcohol at 20℃; for 1h; Inert atmosphere; | 96% |
With sulfuric acid at 20℃; for 1h; Ritter Reaction; | 93% |
sulfuric acid at 20℃; | 93% |
With sulfuric acid Ritter Amidation; | |
Ritter Amidation; |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; | 94% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; | 94% |
Conditions | Yield |
---|---|
With sulfuric acid at 20℃; | 93% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; | 92% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; | 92% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; | 92% |
4'-demethylepipodophyllotoxin
A
4β-azido-4-deoxy-4′-demethylepipodophyllotoxin
B
4β-azido-4'-dimethyl-4-deoxy-epipodophyllotoxin
Conditions | Yield |
---|---|
With tris-(2-chloro-ethyl)-amine; boron trifluoride diethyl etherate In dichloromethane; benzene at -15℃; for 1h; | A 91% B n/a |
4'-demethylepipodophyllotoxin
Dibenzyl phosphite
Conditions | Yield |
---|---|
With tetrachloromethane; dmap; N-ethyl-N,N-diisopropylamine In acetonitrile at -10℃; | 90% |
With dmap; N-ethyl-N,N-diisopropylamine In tetrachloromethane; acetonitrile at -10℃; Inert atmosphere; | 90.1% |
4'-demethylepipodophyllotoxin
4'-demethyl-β-apopicropodophyllotoxin
Conditions | Yield |
---|---|
With sulfuric acid; acetic anhydride for 1h; Heating; | 90% |
4'-demethylepipodophyllotoxin
tert-butyldimethylsilyl chloride
4'-O-tert-butyldimethylsilanyl-4'-O-demethyl-4-epipodophyllotoxin
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 1.5h; | 89% |
With 1H-imidazole In N,N-dimethyl-formamide for 4.5h; | 86% |
With 1H-imidazole In tetrahydrofuran | 60% |
Conditions | Yield |
---|---|
With dicyclohexyl-carbodiimide; dmap In dichloromethane at 20℃; for 2h; | 89% |
Conditions | Yield |
---|---|
With dicyclohexyl-carbodiimide; dmap In dichloromethane at 20℃; for 2h; | 89% |
5-bromo-3-pyridinecarboxylic acid
4'-demethylepipodophyllotoxin
C27H22BrNO9
Conditions | Yield |
---|---|
With dicyclohexyl-carbodiimide; dmap In dichloromethane at 20℃; for 2h; | 87% |
Conditions | Yield |
---|---|
With dicyclohexyl-carbodiimide; dmap In dichloromethane at 20℃; for 2h; | 87% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; | 87% |
4'-demethylepipodophyllotoxin
benzyl chloroformate
4'-benzyloxycarbonyl-4'-demethylpodophyllotoxin
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; | 85.65% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 24.25h; Cooling with ice; | 85% |
4'-demethylepipodophyllotoxin
Conditions | Yield |
---|---|
Stage #1: 4'-demethylepipodophyllotoxin With boron trifluoride diethyl etherate In dichloromethane at 0℃; for 0.166667h; Inert atmosphere; Stage #2: 3,4,6-tri-O-acetyl-2-azido-2-deoxy-β-D-glucopyranose In dichloromethane at -20℃; for 2h; Inert atmosphere; Molecular sieve; | 85% |
Stage #1: 4'-demethylepipodophyllotoxin With boron trifluoride diethyl etherate In dichloromethane at 0℃; Inert atmosphere; Stage #2: 3,4,6-tri-O-acetyl-2-azido-2-deoxy-β-D-glucopyranose In dichloromethane at -5℃; for 4h; Inert atmosphere; |
Conditions | Yield |
---|---|
With dicyclohexyl-carbodiimide; dmap In dichloromethane at 20℃; for 2h; | 83% |
6-Chloro-3-pyridinecarboxylic acid
4'-demethylepipodophyllotoxin
C27H22ClNO9
Conditions | Yield |
---|---|
With dicyclohexyl-carbodiimide; dmap In dichloromethane at 20℃; for 2h; | 83% |
4'-demethylepipodophyllotoxin
2'-chloro-4′-demethylepipodophyllotoxin
Conditions | Yield |
---|---|
With N-chloro-succinimide In N,N-dimethyl-formamide at 0 - 20℃; for 18h; | 82% |
With N-chloro-succinimide In N,N-dimethyl-formamide for 3.5h; Ambient temperature; | 75% |
With N-chloro-succinimide In chloroform at 20℃; for 4h; regioselective reaction; | |
With N-chloro-succinimide In N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere; |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; | 82% |
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