Products

Refine

Country

Business Type

Certificate

Display

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Podophyllotoxin Manufacturer/High quality/Best price/In stock

Cas:518-28-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Assay: Podophyllotoxin 98%; Produced by order; Appearance:White powder Storage:Please keep the product in cool, dry environment and keep in dark place, and seal well. Package:25kg/drum Application:Anti-virus Port:Beijing/Shanghai/Shenzhen/Hangzhou

Podophyllum Resin 98% Podophyllotoxin 98% Sinopodophyllum emodi (Wall.) Extract

Cas:518-28-5

Min.Order:25 Kilogram

FOB Price: $180.0 / 200.0

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 98%min ----------------------------------------------------------------------------------------------

High purity Various Specifications Podophyllotoxin CAS:518-28-5

Cas:518-28-5

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

Specifications Type: Herbal Extract Variety: Podophyllotoxin Form: Powder Part: Root Extraction Type: Solvent Extraction

Podophyllotoxin Powder Extract, Podophyllotoxin 98%,CAS No: 518-28-5

Cas:518-28-5

Min.Order:1 Kilogram

FOB Price: $400.0 / 500.0

Type:Other

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Podophyllotoxin manufacturer with low price

Cas:518-28-5

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

T he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality service Appearance:White

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Podophyllotoxin

Cas:518-28-5

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Podophyllotoxin 518-28-5 GMP Manufacturer

Cas:518-28-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Podophyllotoxin

Cas:518-28-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(-)-Podophyllotoxine

Cas:518-28-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Podophyllotoxin (abbreviated as PPT), otherwise known as podofilox, is a non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species.Under the trade names Condylox, a gel, and Wartec, a solution or cream, it is used on th

bulk pure Podophyllotoxin

Cas:518-28-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Podophyllotoxin 98% CAS :518-28-5

Cas:518-28-5

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

TIANFUCHEM--518-28-5---C22H22O8

Cas:518-28-5

Min.Order:1 Metric Ton

FOB Price: $500.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 518-28-5 with competitive price

Cas:518-28-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Podophyllotoxin

Cas:518-28-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Podophyllotoxin/ LIDE PHARMA- Factory supply / Best price

Cas:518-28-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua

HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

Best Price Podophyllotoxin Podophyllum Resin Hexandrum Extract Podophyllin

Cas:518-28-5

Min.Order:1 Kilogram

FOB Price: $200.0 / 400.0

Type:Trading Company

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

High Quality API 99% purity Podophyllotoxin powder pure Podophyllotoxin raw Powder

Cas:518-28-5

Min.Order:10 Gram

FOB Price: $0.6

Type:Trading Company

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Podophyllotoxin

Cas:518-28-5

Min.Order:5 Gram

FOB Price: $100.0 / 600.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Podophyllotoxin CAS:518-28-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat

Podophyllotoxin CAS:518-28-5

Cas:518-28-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Podophyllinic acid lactone

Cas:518-28-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:518-28-5

Cas:518-28-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: Podophyllotoxin Synonyms: Condyline;(5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-triMethoxyphenyl)-furo(3',4':6,7)naphtho[2,3-d]-1,3-dioxol-6(5aH);(5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-triMethoxyphenyl)-5,5a,8a,9-tet

Podophyllotoxin supplier best quality

Cas:518-28-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Chengdu Biopurify Phytochemicals Ltd.

Chengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medic

Podophyllotoxin 518-28-5

Cas:518-28-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

PODOPHYLLOTOXIN

Cas:518-28-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Podophyllotoxin

Cas:518-28-5

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Synthetic route

Conditions
ConditionsYield
With L-Selectride In tetrahydrofuran at -78℃; for 0.25h;93%
With L-Selectride In tetrahydrofuran at -78℃; for 1.5h; Inert atmosphere;87%
With lithium tri-t-butoxyaluminum hydride In diethyl ether at -78 - 20℃; for 18h; optical yield given as %de; diastereoselective reaction;79%
With L-Selectride In tetrahydrofuran at -78℃; for 2h; Inert atmosphere;70%
(5R,6R,7R,8R)-methyl 8-hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydronaphtho[2,3-d][1,3]dioxole-6-carboxylate
1256-91-3

(5R,6R,7R,8R)-methyl 8-hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydronaphtho[2,3-d][1,3]dioxole-6-carboxylate

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With 4 A molecular sieve; zinc(II) chloride In tetrahydrofuran at 64℃; for 2.5h;85%
With molecular sieve; zinc(II) chloride In tetrahydrofuran75%
With 4 A molecular sieve; zinc(II) chloride In tetrahydrofuran for 2.5h; Heating; Yield given;
(1R,2R,3R,4R)-4-O-(2'-trimethylsilylethoxy)methylpodophyllotoxin
261158-30-9

(1R,2R,3R,4R)-4-O-(2'-trimethylsilylethoxy)methylpodophyllotoxin

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With ethanethiol; magnesium bromide In diethyl ether; benzene at 0 - 20℃; for 11h; SEM deprotection;81%
(5R,5aR,8aR,9R)-9-((tert-butyldimethylsilyl)oxy)-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
112711-16-7

(5R,5aR,8aR,9R)-9-((tert-butyldimethylsilyl)oxy)-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With triethylamine hydrofluoride In acetonitrile for 72h; Ambient temperature;79%
With tetrabutyl ammonium fluoride; acetic acid In tetrahydrofuran at 0℃; for 2h; Inert atmosphere;54%
3-methyl-butan-2-one
563-80-4

3-methyl-butan-2-one

A

7α-[(2R)-2-hydroxy-3-methylbut-2-yl]epi-podophyllotoxin

7α-[(2R)-2-hydroxy-3-methylbut-2-yl]epi-podophyllotoxin

B

7α-[(2S)-2-hydroxy-3-methylbut-2-yl]epi-podophyllotoxin

7α-[(2S)-2-hydroxy-3-methylbut-2-yl]epi-podophyllotoxin

D

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere;A 45%
B 9%
C n/a
D n/a
Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere; optical yield given as %de;A 45%
B 9%
C n/a
D n/a
C32H35NO8S

C32H35NO8S

A

epipodophyllotoxin
4375-07-9

epipodophyllotoxin

B

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With trifluoroacetic acid In tetrahydrofuran; water at 0 - 25℃; for 27h; Inert atmosphere;A 33%
B 43%
With trifluoroacetic acid In tetrahydrofuran; water at 0 - 20℃; for 24h; Overall yield = 76 %; Overall yield = 43 mg;
Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere;A 40%
B n/a
C n/a
Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere; optical yield given as %de;A 40%
B 7%
C n/a
D n/a
Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere; optical yield given as %de;A 40%
B 8%
C n/a
D n/a
Tetrahydro-4H-pyran-4-one
29943-42-8

Tetrahydro-4H-pyran-4-one

A

7α-(4-hydroxytetrahydropyran-4-yl)podophyllotoxin

7α-(4-hydroxytetrahydropyran-4-yl)podophyllotoxin

B

7β-(4-hydroxytetrahydropyran-4-yl)podophyllotoxin

7β-(4-hydroxytetrahydropyran-4-yl)podophyllotoxin

D

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere; optical yield given as %de;A 38%
B 15%
C n/a
D n/a
3-Cyclohexene-1-carboxaldehyde
100-50-5

3-Cyclohexene-1-carboxaldehyde

A

7α-[(1R)-1-cyclohex-3-enyl-1-hydroxymethyl]epi-podophyllotoxin

7α-[(1R)-1-cyclohex-3-enyl-1-hydroxymethyl]epi-podophyllotoxin

B

7α-[(1S)-1-cyclohex-3-enyl-1-hydroxymethyl]epi-podophyllotoxin

7α-[(1S)-1-cyclohex-3-enyl-1-hydroxymethyl]epi-podophyllotoxin

D

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere;A 38%
B 9%
C n/a
D n/a
Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere; optical yield given as %de;A 35%
B 5%
C n/a
D n/a
bicyclo[3.3.1]nonan-9-one
17931-55-4

bicyclo[3.3.1]nonan-9-one

A

7α-(9-hydroxybicyclo[3.3.1]non-9-yl)podophyllotoxin

7α-(9-hydroxybicyclo[3.3.1]non-9-yl)podophyllotoxin

B

7β-(9-hydroxybicyclo[3.3.1]non-9-yl)podophyllotoxin

7β-(9-hydroxybicyclo[3.3.1]non-9-yl)podophyllotoxin

D

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere; optical yield given as %de;A 30%
B 20%
C n/a
D n/a
acetaldehyde
75-07-0

acetaldehyde

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

A

7α-([(1S)-1-hydroxyethyl]-2,2,5-trimethyl-1,3-dioxolan-4-yl)epi-podophyllotoxin acetonide

7α-([(1S)-1-hydroxyethyl]-2,2,5-trimethyl-1,3-dioxolan-4-yl)epi-podophyllotoxin acetonide

B

7α-([(1R)-1-hydroxyethyl]-2,2,5-trimethyl-1,3-dioxolan-4-yl)epi-podophyllotoxin acetonide

7α-([(1R)-1-hydroxyethyl]-2,2,5-trimethyl-1,3-dioxolan-4-yl)epi-podophyllotoxin acetonide

D

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
Stage #1: acetaldehyde; podophyllotoxone With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere;
Stage #2: 2,2-dimethoxy-propane With chloro-trimethyl-silane In acetone for 0.0833333h; Inert atmosphere;
A 15%
B 30%
C n/a
D n/a
Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere;A 30%
B 8%
C n/a
D n/a
Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere;A 30%
B n/a
C n/a
Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at -20 - -10℃; for 4h; McMurry reaction; Inert atmosphere;A 15%
B n/a
C n/a
podophyllotoxin-7′-O-β-D-glucopyranoside
16481-54-2

podophyllotoxin-7′-O-β-D-glucopyranoside

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With emulsin-substance
4-demethylpodophyllotoxin
40505-27-9

4-demethylpodophyllotoxin

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With methanol; diethyl ether; acetone
In methanol; diethyl ether; acetone for 24h; Ambient temperature;20 mg
podophyllotoxinyl acetate
1180-34-3

podophyllotoxinyl acetate

A

(5aR,8aS,9R)-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxole-5,8-dione
477-48-5

(5aR,8aS,9R)-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxole-5,8-dione

C

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
In dimethyl sulfoxide for 72h; Forsythia intermedia; Yield given. Yields of byproduct given;
podophyllotoxin-7′-O-β-D-glucopyranoside
16481-54-2

podophyllotoxin-7′-O-β-D-glucopyranoside

B

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
In dimethyl sulfoxide for 72h; Forsythia intermedia; Yield given. Yields of byproduct given;
Conditions
ConditionsYield
With aspergillus niger sp In ethanol for 72h;
Multi-step reaction with 3 steps
1: N-Bromosuccinimide / 1,4-dioxane / 0.33 h / 20 °C / Inert atmosphere; Schlenk technique; Irradiation
2: dipyridinium dichromate / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere
3: L-Selectride / tetrahydrofuran / 1.5 h / -78 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: chromium(VI) oxide; 3,5-dimethyl-1H-pyrazole / dichloromethane / 2 h / 0 °C
2: L-Selectride / tetrahydrofuran / 0.25 h / -78 °C
View Scheme
Conditions
ConditionsYield
With zinc(II) tetrahydroborate In diethyl ether; benzene for 3.5h; Product distribution; Ambient temperature; different reducing agents, solvents, reaction temperatures and times;
With zinc(II) tetrahydroborate In diethyl ether; benzene for 3.5h; Ambient temperature; Yield given. Yields of byproduct given;
9-Chloro-9-desoxypodophyllotoxin
7401-22-1

9-Chloro-9-desoxypodophyllotoxin

A

4β-azido-4-deoxypodophyllotoxin
155252-34-9

4β-azido-4-deoxypodophyllotoxin

B

4'-O-trimethyl-4-azido-4-desoxypodophyllotoxin
155325-17-0

4'-O-trimethyl-4-azido-4-desoxypodophyllotoxin

C

epipodophyllotoxin
4375-07-9

epipodophyllotoxin

D

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With sodium azide In water; acetone at 50℃; for 5h; Yield given. Yields of byproduct given;
(3S,4R)-4-(Benzenesulfinyl-benzo[1,3]dioxol-5-yl-methyl)-3-[hydroxy-(3,4,5-trimethoxy-phenyl)-methyl]-dihydro-furan-2-one

(3S,4R)-4-(Benzenesulfinyl-benzo[1,3]dioxol-5-yl-methyl)-3-[hydroxy-(3,4,5-trimethoxy-phenyl)-methyl]-dihydro-furan-2-one

podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With boron trifluoride diethyl etherate; mercury(II) oxide for 28h; Yield given;
hydrogenchloride
7647-01-0

hydrogenchloride

acetone
67-64-1

acetone

epipodophyllotoxin
4375-07-9

epipodophyllotoxin

podofilox
518-28-5

podofilox

hydrogenchloride
7647-01-0

hydrogenchloride

podophyllinic acid hydrazide
78178-41-3

podophyllinic acid hydrazide

podofilox
518-28-5

podofilox

pyrrolidine
123-75-1

pyrrolidine

podofilox
518-28-5

podofilox

picropodophyllic acid pyrrolidinyl amide
291272-81-6

picropodophyllic acid pyrrolidinyl amide

Conditions
ConditionsYield
In benzene at 50℃; for 46h; Inert atmosphere;100%
ethylamine
75-04-7

ethylamine

podofilox
518-28-5

podofilox

N-ethyl picropodophyllamide
116606-76-9

N-ethyl picropodophyllamide

Conditions
ConditionsYield
In water for 1.5h; Reflux;100%
podofilox
518-28-5

podofilox

2’-chloropodophyllotoxin
1449601-57-3

2’-chloropodophyllotoxin

Conditions
ConditionsYield
With N-chloro-succinimide; 2,2,6,6-tetramethylpiperidin-1-oxoammonium trifluoromethanesulfonate In chloroform at 25℃; for 12h; Reagent/catalyst; Schlenk technique;99%
With N-chloro-succinimide In N,N-dimethyl-formamide at 0 - 20℃; for 20h;85%
With N-chloro-succinimide at 0 - 20℃; for 24h;85%
tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

podofilox
518-28-5

podofilox

(5R,5aR,8aR,9R)-9-((tert-butyldimethylsilyl)oxy)-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
112711-16-7

(5R,5aR,8aR,9R)-9-((tert-butyldimethylsilyl)oxy)-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide98%
With 1H-imidazole90%
With 1H-imidazole In N,N-dimethyl-formamide90%
9,12-epoxy-9,11-octadecadienoic acid
4179-44-6

9,12-epoxy-9,11-octadecadienoic acid

podofilox
518-28-5

podofilox

4-O-podophyllotoxinyl 9,12-epoxyoctadeca-9,11-dienoate

4-O-podophyllotoxinyl 9,12-epoxyoctadeca-9,11-dienoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 2h; Esterification;98%
trans-ximenynic acid
2578-97-4, 136145-04-5, 557-58-4

trans-ximenynic acid

podofilox
518-28-5

podofilox

4-O-podophyllotoxinyl octadec-11E-en-9-ynoate

4-O-podophyllotoxinyl octadec-11E-en-9-ynoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 2h; Esterification;98%
5,6-dithia-decanedioic acid
2906-60-7

5,6-dithia-decanedioic acid

podofilox
518-28-5

podofilox

C52H54O18S2

C52H54O18S2

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 2h; Inert atmosphere;98%
C39H32O9
1374991-25-9

C39H32O9

podofilox
518-28-5

podofilox

C49H44O15

C49H44O15

Conditions
ConditionsYield
With H3P*C18H15P*C2F6NO4S2(1-)*Au(1+) In dichloromethane at 20℃; Inert atmosphere; Green chemistry;98%
t-butyldimethylsiyl triflate
69739-34-0

t-butyldimethylsiyl triflate

podofilox
518-28-5

podofilox

(5R,5aR,8aR,9R)-9-((tert-butyldimethylsilyl)oxy)-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
112711-16-7

(5R,5aR,8aR,9R)-9-((tert-butyldimethylsilyl)oxy)-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one

Conditions
ConditionsYield
With 2,6-dimethylpyridine In dichloromethane at 0℃; silylation;97%
succinic acid
110-15-6

succinic acid

podofilox
518-28-5

podofilox

C48H46O18

C48H46O18

Conditions
ConditionsYield
With dmap; 1,2-dichloro-ethane In dichloromethane at 20℃; for 24h; Inert atmosphere;97%
ortho-(cyclopropylethynyl)benzoic acid
1313028-09-9

ortho-(cyclopropylethynyl)benzoic acid

podofilox
518-28-5

podofilox

podophyllotoxin 4-O-ortho-cyclopropylethynylbenzoate

podophyllotoxin 4-O-ortho-cyclopropylethynylbenzoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 2h;97%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20 - 35℃; for 2h; Inert atmosphere;97%
8-(2-adamantyloxy)-8-oxo-octanoic acid
1338797-64-0

8-(2-adamantyloxy)-8-oxo-octanoic acid

podofilox
518-28-5

podofilox

2-adamantyl (5R,5aR,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,-3]benzodioxol-5-yl suberate

2-adamantyl (5R,5aR,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,-3]benzodioxol-5-yl suberate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 12h;97%
podofilox
518-28-5

podofilox

Conditions
ConditionsYield
With phosphorus tribromide In benzene for 1h; Heating;96%
With hydrogen bromide In diethyl ether; dichloromethane at 0℃; for 48h;
cis-9,trans-11-octadecadienoic acid
544-70-7, 544-71-8, 872-23-1, 1839-11-8, 2540-56-9

cis-9,trans-11-octadecadienoic acid

podofilox
518-28-5

podofilox

4-O-podophyllotoxinyl octadeca-9Z,11E-dienoate

4-O-podophyllotoxinyl octadeca-9Z,11E-dienoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 2h; Esterification;96%
11,12-E-epoxyoctadec-9-ynoic acid

11,12-E-epoxyoctadec-9-ynoic acid

podofilox
518-28-5

podofilox

4-O-podophyllotoxinyl 11,12-E-epoxyoctadec-9-ynoate

4-O-podophyllotoxinyl 11,12-E-epoxyoctadec-9-ynoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 2h; Esterification;96%
8-(2-adamantyloxy)-8-oxo-octanoic acid
1338797-64-0

8-(2-adamantyloxy)-8-oxo-octanoic acid

podofilox
518-28-5

podofilox

2-adamantyl (5R,5aR,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,-3]benzodioxol-5-yl suberate

2-adamantyl (5R,5aR,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,-3]benzodioxol-5-yl suberate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 12h;97%
podofilox
518-28-5

podofilox

1α-bromo-desoxypodophyllotoxin
106636-74-2

1α-bromo-desoxypodophyllotoxin

Conditions
ConditionsYield
With phosphorus tribromide In benzene for 1h; Heating;96%
With hydrogen bromide In diethyl ether; dichloromethane at 0℃; for 48h;
podofilox
518-28-5

podofilox

4'-O-trimethyl-4-azido-4-desoxypodophyllotoxin
155325-17-0

4'-O-trimethyl-4-azido-4-desoxypodophyllotoxin

Conditions
ConditionsYield
With sodium azide; trifluoroacetic acid In dichloromethane at 25℃; Cooling with ice;96%
With sodium azide; phosphorus tribromide
Multi-step reaction with 2 steps
1: PBr3 / benzene / 1 h / Heating
2: NaN3 / dimethylformamide
View Scheme
Boc-D-Trp-OH
5241-64-5

Boc-D-Trp-OH

podofilox
518-28-5

podofilox

(5R,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl (tert-butoxycarbonyl)-D-tryptophanate

(5R,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl (tert-butoxycarbonyl)-D-tryptophanate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 4h;95.5%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; Inert atmosphere;72%
L-N-Boc-Ala
15761-38-3

L-N-Boc-Ala

podofilox
518-28-5

podofilox

(5R,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[30,4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl(tert-butoxycarbonyl)alaninate

(5R,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[30,4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl(tert-butoxycarbonyl)alaninate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 12h;95.4%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 12h;95.4%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 4h;92.1%
podofilox
518-28-5

podofilox

epipodophyllotoxin
4375-07-9

epipodophyllotoxin

Conditions
ConditionsYield
Stage #1: podofilox With methanesulfonic acid; sodium bromide In acetonitrile at 20℃; for 1h; Inert atmosphere; Green chemistry;
Stage #2: With barium carbonate In water at 20℃; Green chemistry;
95%
Stage #1: podofilox With sodium iodide In acetonitrile for 0.0833333h;
Stage #2: With boron trifluoride diethyl etherate In acetonitrile at 0 - 20℃;
Stage #3: With water; barium carbonate In acetone; acetonitrile at 20℃; for 0.5h;
85%
Stage #1: podofilox With sodium iodide In acetonitrile at 20℃; for 0.0833333h;
Stage #2: With boron trifluoride diethyl etherate at 0℃; for 0.25h;
Stage #3: With barium carbonate In water; acetone at 20℃; for 2h;
72%
Phenoxyacetyl chloride
701-99-5

Phenoxyacetyl chloride

podofilox
518-28-5

podofilox

podophyllotoxinyl phenoxyacetate

podophyllotoxinyl phenoxyacetate

Conditions
ConditionsYield
In pyridine; benzene Ambient temperature;95%
allyl-trimethyl-silane
762-72-1

allyl-trimethyl-silane

podofilox
518-28-5

podofilox

4-deoxy-4-allyl-(epi)-podophyllotoxin
136723-80-3

4-deoxy-4-allyl-(epi)-podophyllotoxin

Conditions
ConditionsYield
With 4 A molecular sieve; boron trifluoride diethyl etherate In dichloromethane at 25℃; for 4h;95%
N-(tert-butoxycarbonyl)sarcosine
13734-36-6

N-(tert-butoxycarbonyl)sarcosine

podofilox
518-28-5

podofilox

(5R,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[30,4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl-N-(tertbutoxycarbonyl)-N-methylglycinate

(5R,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[30,4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl-N-(tertbutoxycarbonyl)-N-methylglycinate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 4h;94.2%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 12h;90.3%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 12h;90.3%
succinic acid anhydride
108-30-5

succinic acid anhydride

podofilox
518-28-5

podofilox

Succinylpodophyllotoxin
47789-93-5

Succinylpodophyllotoxin

Conditions
ConditionsYield
With dmap; triethylamine In chloroform at 20℃; for 1h; Inert atmosphere;94%
With 1H-imidazole; dmap at 20℃; for 13h;91%
With pyridine at 25℃; for 16h;73%
9,10-dibromooctadecanoic acid
19117-94-3

9,10-dibromooctadecanoic acid

podofilox
518-28-5

podofilox

4-O-podophyllotoxinyl 9,10-dibromooctadecanoate

4-O-podophyllotoxinyl 9,10-dibromooctadecanoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 2h; Esterification;94%
1-(tert-butoxycarbonyl)-L-proline
15761-39-4

1-(tert-butoxycarbonyl)-L-proline

podofilox
518-28-5

podofilox

1-(tert-butyl)-2-((5R,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[30,4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl)pyrrolidine-1,2-dicarboxylate

1-(tert-butyl)-2-((5R,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[30,4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl)pyrrolidine-1,2-dicarboxylate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 12h;94%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 12h;94%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 20h;
7-(2-adamantyloxy)-7-oxo-heptanoic acid
1338797-61-7

7-(2-adamantyloxy)-7-oxo-heptanoic acid

podofilox
518-28-5

podofilox

2-adamantyl (5R,5aR,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,-3]benzodioxol-5-yl pimelate

2-adamantyl (5R,5aR,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,-3]benzodioxol-5-yl pimelate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 12h;94%
p-tolyl 2-O-acetyl-3,4,6-tri-O-benzyl-1-thio-β-D-galactopyranoside
897364-02-2

p-tolyl 2-O-acetyl-3,4,6-tri-O-benzyl-1-thio-β-D-galactopyranoside

podofilox
518-28-5

podofilox

7-O-(2-O-acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)podophyllotoxin

7-O-(2-O-acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)podophyllotoxin

Conditions
ConditionsYield
With rhodium (II) octanoate dimer; 2,6-di-tert-butyl-4-methylpyridinium trifluoromethanesulfonate; methyl 2-(4-chlorophenyl)-2-diazoacetate In dichloromethane at 0℃; for 2h; Molecular sieve;94%
hydrazine carboxamide
4426-72-6, 51433-48-8

hydrazine carboxamide

podofilox
518-28-5

podofilox

C23H27N3O9

C23H27N3O9

Conditions
ConditionsYield
With acetic acid In methanol for 6h; Reflux;94%
podofilox
518-28-5

podofilox

podophyllinic acid hydrazide
78178-41-3

podophyllinic acid hydrazide

Conditions
ConditionsYield
With acetic acid; hydrazine In methanol for 6h; Reflux;94%

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View