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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

3-ethynyltoluene

Cas:766-82-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

3-Ethynyltoluene

Cas:766-82-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

m-Tolylacetylene

Cas:766-82-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

3-Ethynyltoluene

Cas:766-82-5

Min.Order:1 Gram

FOB Price: $12.0 / 15.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 766-82-5 with best quality

Cas:766-82-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product name:3-Ethynyltoluene CAS No:766-82-5 Appearance: White or colorless crystalline Content:98% Appearance:White or colorless crystalline Storage:Store in cool and dry place, away

3-Ethynyltoluene

Cas:766-82-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:766-82-5

Cas:766-82-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Methyl phenylacetylene

Cas:766-82-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply m-Tolylacetylene

Cas:766-82-5

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

766-82-5 3-Ethynyltoluene

Cas:766-82-5

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

3-Ethynyltoluene Basic information Product Name: 3-Ethynyltoluene Synonyms: m-Ethylnyltoluene;3-Ethynyltoluene, 1-Ethynyl-3-methylbenzene;1-ETHYNYL-3-METHYLBENZENE;Benzene,1-ethynyl-3-methyl-;3'-METHYLPHENYL ACETYLENE;3-ETHYNYLTOLUENE;Benz

3-Ethynyltoluene

Cas:766-82-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in

SAGECHEM/ 3-Ethynyltoluene /Manufacturer in China

Cas:766-82-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Shanghai Massive Chemical Technology Co., Ltd. is engaged in development, production and marketing Specialty Chemicals to satisfy the changing needs of the chemical industry. We specialize in manufacturing high quality of Advanced Intermediates, Sp

3-Ethynyltoluene

Cas:766-82-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratoryAppearance:colorless to light yellow liquid Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-Ethynyltoluene cas no. 766-82-5 98%

Cas:766-82-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

3-Ethynyltoluene

Cas:766-82-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

3-Ethynyltoluene

Cas:766-82-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

M-Tolylacetylene

Cas:766-82-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

"HANGZHOU TIANYE CHEMICALS Co.LTD , Located in Eastern Science and Innovation Park Hangzhou .We are a high-tech enterprise specialized in technical research and development, production, development and trade of chemical products. We supply Multiple s

3-Ethynyltoluene

Cas:766-82-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white crystalline powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use

3-Ethynyltoluene

Cas:766-82-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

3-EthynyltolueneAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea, by express

3-Ethynyltoluene

Cas:766-82-5

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low priceAppearance:Clear light yellow to brown liquid Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

m-Tolylacetylene

Cas:766-82-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-Ethynyltoluene

Cas:766-82-5

Min.Order:0

Negotiable

Type:Other

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

3-Ethynyltoluene

Cas:766-82-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:White powder Storage:keep sealed and keep from direct light Package:According client's requirements Application:pharmaceutica

3-Ethynyltoluene manufacturer

Cas:766-82-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3-Ethynyltoluene

Cas:766-82-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

3-Ethynyltoluene

Cas:766-82-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

3'-Methylphenylacetylene

Cas:766-82-5

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

3-Ethynyltoluene

Cas:766-82-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Watson International Ltd

Watson International Ltd' has a very strong R&D and technical capacity supported by FCAD's platform. The subsidiaries under FCAD Group have accumulated much know-how of different fine chemical branches. For example, Apnoke Scientific L

3-Ethynyltoluene

Cas:766-82-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

suzhou BetterBioChem Co., Ltd.

Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

3-ETHYNYLTOLUENE

Cas:766-82-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(2-(3-methylphenyl)ethynyl)trimethylsilane
40230-90-8

(2-(3-methylphenyl)ethynyl)trimethylsilane

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
With potassium carbonate In methanol at 25℃; for 3h;93%
With potassium trimethylsilonate In dimethyl sulfoxide at 60℃; under 760.051 Torr; for 7h; Catalytic behavior; Reagent/catalyst; Solvent; Sealed tube;93%
With potassium carbonate In methanol; dichloromethane for 1h; Inert atmosphere;72%
N-methylmethane sulphonamide
1184-85-6

N-methylmethane sulphonamide

1-(bromo-ethynyl)-3-methyl-benzene
33675-43-3

1-(bromo-ethynyl)-3-methyl-benzene

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
With 1,10-Phenanthroline; copper(ll) sulfate pentahydrate; potassium carbonate; toluene at 80℃; Inert atmosphere;90%
2-methyl-4-(3'-methylphenyl)but-3-yn-2-ol
63079-66-3

2-methyl-4-(3'-methylphenyl)but-3-yn-2-ol

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
With potassium hydroxide In methanol; toluene at 140℃;72%
1-(1,1-Dichloro-ethyl)-3-methyl-benzene
16035-10-2

1-(1,1-Dichloro-ethyl)-3-methyl-benzene

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
With potassium hydroxide In ethanol Heating;46%
3-Iodotoluene
625-95-6

3-Iodotoluene

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
37%
Multi-step reaction with 2 steps
1: dimethylformamide / 160 °C
2: (i) EtMgBr, (ii) KOH
View Scheme
Multi-step reaction with 2 steps
1: (i) nBuLi, (ii) CuI, (iii) /BRN= 1903634/
2: (i) aq. CF3CO2H, (ii) NaOMe
View Scheme
acetaldehyde
75-07-0

acetaldehyde

m-tolylmagnesium bromide
28987-79-3

m-tolylmagnesium bromide

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
Multistep reaction;
methanol
67-56-1

methanol

Methyl fluoride
593-53-3

Methyl fluoride

phenylacetylene
536-74-3

phenylacetylene

A

1-Phenylprop-1-yne
673-32-5

1-Phenylprop-1-yne

B

1-ethynyl-2-methylbenzene
766-47-2

1-ethynyl-2-methylbenzene

C

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

D

2-Methylacetophenone
577-16-2, 122382-54-1

2-Methylacetophenone

E

4-n-methylphenylacetylene
766-97-2

4-n-methylphenylacetylene

Conditions
ConditionsYield
at 37℃; under 700 Torr; Product distribution; Mechanism; Irradiation; various concentration of substrates, addition of various amounts of NEt3;
Methyl fluoride
593-53-3

Methyl fluoride

phenylacetylene
536-74-3

phenylacetylene

A

1-Phenylprop-1-yne
673-32-5

1-Phenylprop-1-yne

B

1-ethynyl-2-methylbenzene
766-47-2

1-ethynyl-2-methylbenzene

C

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

D

4-n-methylphenylacetylene
766-97-2

4-n-methylphenylacetylene

Conditions
ConditionsYield
at 37℃; under 700 Torr; Product distribution; Mechanism; Irradiation; various concentration of substrates, addition of various amounts of NEt3;
1-phenyl-3-(3-methylphenyl)prop-2-yn-1-one
14674-99-8

1-phenyl-3-(3-methylphenyl)prop-2-yn-1-one

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
(i) EtMgBr, (ii) KOH; Multistep reaction;
1-(3-tolyl)-3,3-diethoxyprop-1-yne
62358-87-6

1-(3-tolyl)-3,3-diethoxyprop-1-yne

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
(i) aq. CF3CO2H, (ii) NaOMe; Multistep reaction;
Butadiyne
460-12-8

Butadiyne

toluene
108-88-3

toluene

A

1-ethynyl-2-methylbenzene
766-47-2

1-ethynyl-2-methylbenzene

B

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

C

4-n-methylphenylacetylene
766-97-2

4-n-methylphenylacetylene

Conditions
ConditionsYield
Alkylation; Irradiation;
meta-bromotoluene
591-17-3

meta-bromotoluene

A

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

B

Co2(CO)8

Co2(CO)8

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Et3N; CuI / Pd(PPh3)4 / Heating
2: K2CO3 / methanol / 20 °C
View Scheme
meta-bromotoluene
591-17-3

meta-bromotoluene

amalgamated aluminium

amalgamated aluminium

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 73 percent / Et3N, pyridine, Ph3P, CuI / (Ph3P)2PdCl2 / 7 h / Heating
2: 72 percent / KOH / toluene; methanol / 140 °C
View Scheme
3-Methylacetophenone
585-74-0

3-Methylacetophenone

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 84 percent / PCl5 / 12 h / 20 °C
2: 46 percent / KOH / ethanol / Heating
View Scheme
meta-bromotoluene
591-17-3

meta-bromotoluene

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
Stage #1: meta-bromotoluene; trimethylsilylacetylene With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In acetonitrile at 60℃; for 16h; Inert atmosphere;
Stage #2: With tetrabutyl ammonium fluoride In acetonitrile at 20℃; for 2h;
meta-bromotoluene
591-17-3

meta-bromotoluene

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: bis(triphenylphosphine)palladium(II) dichloride; copper(l) iodide; triethylamine / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere
2: potassium carbonate / methanol / 3 h / 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 12 h / Inert atmosphere
2: potassium carbonate / methanol / 3 h / 20 °C / Inert atmosphere
View Scheme
dimethyl 1-(1-diazo-2-oxopropyl)phosphonate
90965-06-3

dimethyl 1-(1-diazo-2-oxopropyl)phosphonate

m-tolyl aldehyde
620-23-5

m-tolyl aldehyde

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
With potassium carbonate In methanol at 60℃; for 0.75h; Seyferth-Gilbert Homologation; Microwave irradiation;
3-Iodotoluene
625-95-6

3-Iodotoluene

acetylene
74-86-2

acetylene

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine In dimethylsulfoxide-d6 at 20℃; for 2h; Sonogashira Cross-Coupling;86 %Chromat.
trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

1-halo-3-methylbenzene

1-halo-3-methylbenzene

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
Stage #1: trimethylsilylacetylene; 1-halo-3-methylbenzene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine for 12h; Inert atmosphere;
Stage #2: With potassium carbonate In methanol for 2h;
3-Iodotoluene
625-95-6

3-Iodotoluene

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Conditions
ConditionsYield
Stage #1: 3-Iodotoluene; trimethylsilylacetylene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 20℃; for 12h; Inert atmosphere;
Stage #2: With methanol; potassium carbonate at 20℃; for 3h; Inert atmosphere;
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; Inert atmosphere;
Tetrahydro-4H-pyran-4-one
29943-42-8

Tetrahydro-4H-pyran-4-one

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

4-(m-tolylethynyl)tetrahydro-2H-pyran-4-ol
1435770-36-7

4-(m-tolylethynyl)tetrahydro-2H-pyran-4-ol

Conditions
ConditionsYield
Stage #1: 1-ethynyl-3-methyl-benzene With n-butyllithium In tetrahydrofuran; hexane at 20℃; for 0.0833333h;
Stage #2: With lithium bromide In tetrahydrofuran; hexane at 20℃; for 0.5h;
Stage #3: Tetrahydro-4H-pyran-4-one In tetrahydrofuran; hexane at -78 - 20℃; for 0.666667h;
100%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

HSiPh3
789-25-3

HSiPh3

(E)-(3-methylstyryl)triphenylsilane

(E)-(3-methylstyryl)triphenylsilane

Conditions
ConditionsYield
With C24H23ClCrIrNO3 In 1,1,2,2-tetrachloroethane at 40℃; for 2h; Inert atmosphere; Schlenk technique; regioselective reaction;100%
With C77H70N2OPtSi2 In toluene at 40℃; for 24h; Catalytic behavior; Reagent/catalyst; Inert atmosphere; Schlenk technique; stereoselective reaction;99 %Chromat.
Methyl azidoacetate
1816-92-8

Methyl azidoacetate

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

methyl 2-(4-(m-tolyl)-1H-1,2,3-triazol-1-yl)acetate

methyl 2-(4-(m-tolyl)-1H-1,2,3-triazol-1-yl)acetate

Conditions
ConditionsYield
With copper(II) sulfate; sodium L-ascorbate In water at 20℃; Reagent/catalyst; Solvent;100%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

1,4-bis(3-methylphenyl)-1,3-butadiyne

1,4-bis(3-methylphenyl)-1,3-butadiyne

Conditions
ConditionsYield
With CuO-Fe3O4; potassium tert-butylate; oxygen at 60℃; for 72h; Glaser Coupling;99%
With copper(l) iodide; oxygen; benzylamine In neat (no solvent) at 20℃; under 760.051 Torr; for 12h; Green chemistry;99%
With sodium acetate; silver sulfate In dimethyl sulfoxide at 90℃; for 11h;99%
2-Iodophenol
533-58-4

2-Iodophenol

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

2‐m‐tolylbenzofuran
92724-29-3

2‐m‐tolylbenzofuran

Conditions
ConditionsYield
With bis(η3-allyl-μ-chloropalladium(II)); tetraphosphine N,N,N′,N′-tetra(diphenylphosphinomethyl)-pyridine-2,6-diamine; caesium carbonate In N,N-dimethyl-formamide at 130℃; for 3h; Sonogashira Cross-Coupling; Schlenk technique; Inert atmosphere;99%
With potassium phosphate; C45H51Cl4N7Pd2 In dimethyl sulfoxide at 90℃; for 16h; Reagent/catalyst; Schlenk technique;93%
With potassium phosphate In N,N-dimethyl-formamide at 160℃; Schlenk technique; Inert atmosphere; Glovebox; Green chemistry;87%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

(E)-3,3'-(but-1-en-3-yne-1,4-diyl)bis(methylbenzene)
1133321-55-7

(E)-3,3'-(but-1-en-3-yne-1,4-diyl)bis(methylbenzene)

Conditions
ConditionsYield
With [{Pd(μ-OH)Cl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)}2]; potassium hydroxide In ethanol at 22℃; for 24h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; Schlenk technique; stereoselective reaction;99%
With C77H74N2OPtSi2 In toluene at 60℃; Reagent/catalyst; Inert atmosphere; diastereoselective reaction;95%
With Wilkinson's catalyst; sodium dodecyl-sulfate In water; toluene at 50℃; for 15h;83%
ortho-methylphenyl iodide
615-37-2

ortho-methylphenyl iodide

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

2-m-tolyl-1-o-tolylethyne
205529-19-7

2-m-tolyl-1-o-tolylethyne

Conditions
ConditionsYield
With potassium carbonate; copper(II) oxide In dimethyl sulfoxide at 160℃; for 12h; Sonogashira coupling; Inert atmosphere;99%
With C17H32Cl2N4OPd; potassium carbonate In ethanol at 80℃; for 1h; Sonogashira Cross-Coupling;89%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

ethyl-3,3,3-trifluoropyruvate
13081-18-0

ethyl-3,3,3-trifluoropyruvate

ethyl 2-hydroxy-4-m-tolyl-2-(trifluoromethyl)but-3-ynoate

ethyl 2-hydroxy-4-m-tolyl-2-(trifluoromethyl)but-3-ynoate

Conditions
ConditionsYield
With [Rh{(S,S)-4-NO2-Phebox-Bn}(OAc)2]*H2O In diethyl ether at 25℃; for 24h; Inert atmosphere; enantioselective reaction;99%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

benzoyl(3,4-dihydroisoquinolinium-2-yl)azanide
42046-26-4

benzoyl(3,4-dihydroisoquinolinium-2-yl)azanide

C25H22N2O
1337924-72-7

C25H22N2O

Conditions
ConditionsYield
With copper diacetate; 2,6-bis[(4R)-5,5-dihydro-4-phenyl-2-oxazolyl]pyridine In dichloromethane at 0℃; for 12h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;99%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

1-(azidomethyl)-3-bromobenzene
126799-86-8

1-(azidomethyl)-3-bromobenzene

1-(3-bromobenzyl)-4-(3-methylphenyl)-1H-1,2,3-triazole
1361946-54-4

1-(3-bromobenzyl)-4-(3-methylphenyl)-1H-1,2,3-triazole

Conditions
ConditionsYield
With Octanoic acid; C27H31AgNO3P In toluene at 20℃; for 48h; Inert atmosphere; regioselective reaction;99%
methanesulfonic acid
75-75-2

methanesulfonic acid

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

C10H12O3S

C10H12O3S

Conditions
ConditionsYield
With chloro(1,5-cyclooctadiene)rhodium(I) dimer; triphenylphosphine In 1,2-dichloro-ethane at 70℃; for 2h; regioselective reaction;99%
With immobilized Wilkinson’s complex, RhCl(PPh3)3 supported on (diphenylphosphine) In 1,2-dichloro-ethane at 70℃; for 24h; stereoselective reaction;92%
bromobenzene
108-86-1

bromobenzene

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

1-methyl-3-(2-phenylethynyl)benzene
14635-91-7

1-methyl-3-(2-phenylethynyl)benzene

Conditions
ConditionsYield
With water; potassium carbonate In 1-methyl-pyrrolidin-2-one at 135℃; for 24h; Catalytic behavior; Sonogashira Cross-Coupling;99%
With tetrabutylammomium bromide; sodium acetate In dimethyl sulfoxide at 120℃; for 40h; Sonogashira Cross-Coupling; Inert atmosphere;89%
1,1,1-trifluoroacetophenone
434-45-7

1,1,1-trifluoroacetophenone

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

1,1,1-trifluoro-2-phenyl-4-(m-tolyl)but-3-yn-2-ol
1590442-96-8

1,1,1-trifluoro-2-phenyl-4-(m-tolyl)but-3-yn-2-ol

Conditions
ConditionsYield
With C42H62AgN4(1+)*BF4(1-) In water at 60℃; for 15h;99%
With triphenylphosphine In water at 60℃; for 2h; Schlenk technique; Inert atmosphere; Green chemistry;97%
With copper diacetate; potassium carbonate In dimethyl sulfoxide at 70℃; for 24h; Temperature;97%
With copper(I) oxide; potassium carbonate In 1-methyl-pyrrolidin-2-one at 50℃; for 24h;68%
With C54H56N8Ru(2+)*2F6P(1-); triethylamine In tetrahydrofuran at 60℃; for 16h; Inert atmosphere; Schlenk technique; Sealed tube;
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

2,6-dichlorobenzaldehyde
83-38-5

2,6-dichlorobenzaldehyde

C16H12Cl2O
1590443-25-6

C16H12Cl2O

Conditions
ConditionsYield
With 2,2,2-Trifluoroacetophenone; triphenylphosphine In water at 60℃; for 2h; Schlenk technique; Inert atmosphere; Green chemistry;99%
piperidine
110-89-4

piperidine

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

benzaldehyde
100-52-7

benzaldehyde

C21H23N

C21H23N

Conditions
ConditionsYield
With Cu(at)MOF-5-C In toluene at 110℃; for 6h; Inert atmosphere;99%
With [copper(I)]2[(2-picolyliminomethyl)pyrrole]2 In toluene at 110℃; for 2h; Inert atmosphere;98%
With silver carbonate In neat (no solvent) at 110℃; for 0.916667h;96%
With cycloaurated phosphinothioicamide gold(III) complex immobilized in a silica-supported ionic liquid In neat (no solvent) at 60℃; for 8h; Green chemistry;
formic acid
64-18-6

formic acid

iodobenzene
591-50-4

iodobenzene

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

1-phenyl-3-(3-methylphenyl)prop-2-yn-1-one
14674-99-8

1-phenyl-3-(3-methylphenyl)prop-2-yn-1-one

Conditions
ConditionsYield
With palladium diacetate; triethylamine; dicyclohexyl-carbodiimide; triphenylphosphine In toluene at 30℃; Inert atmosphere; Sealed tube;99%
With triethylamine; dicyclohexyl-carbodiimide In toluene at 30℃; for 24h; Inert atmosphere;96%
With palladium diacetate; acetic anhydride; triethylamine; triphenylphosphine In toluene at 30℃; Sonogashira Cross-Coupling; Inert atmosphere;82%
With iodine; palladium diacetate; triethylamine; triphenylphosphine In toluene at 40℃; for 4h; Sonogashira Cross-Coupling; Sealed tube;82%
2-azido-1-(piperidin-1-yl)ethan-1-one
1132647-39-2

2-azido-1-(piperidin-1-yl)ethan-1-one

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

1-(piperidin-1-yl)-2-(4-m-tolyl-1H-1,2,3-triazol-1-yl)ethanone

1-(piperidin-1-yl)-2-(4-m-tolyl-1H-1,2,3-triazol-1-yl)ethanone

Conditions
ConditionsYield
With copper(II) sulfate; sodium L-ascorbate In water; tert-butyl alcohol at 20℃; for 24h;99%
1-benzylisatin

1-benzylisatin

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

1-benzyl-3-hydroxy-3-(m-tolylethynyl)indolin-2-one

1-benzyl-3-hydroxy-3-(m-tolylethynyl)indolin-2-one

Conditions
ConditionsYield
With C42H62AgN4(1+)*BF4(1-) In methanol; water at 60℃; for 15h;99%
With C30H22N4O2Rh(1+)*F6P(1-) In tetrahydrofuran at 50℃; Schlenk technique; Sealed tube;92%
With potassium tert-butylate In toluene at 20℃; Inert atmosphere;48%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

1-(3-chlorobenzyl)-4-(m-tolyl)-1H-1,2,3-triazole

1-(3-chlorobenzyl)-4-(m-tolyl)-1H-1,2,3-triazole

Conditions
ConditionsYield
With (1,3-bis(2,6-dimethylphenyl)thiourea)Cu(Cl)(1,3-bis(2,6-dimethylphenyl)thiourea) In neat (no solvent) at 20℃; for 1.5h;99%
1,1,1-trifluoroacetophenone
434-45-7

1,1,1-trifluoroacetophenone

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

(S)-1,1,1-trifluoro-2-phenyl-4-(m-tolyl)but-3-yn-2-ol

(S)-1,1,1-trifluoro-2-phenyl-4-(m-tolyl)but-3-yn-2-ol

Conditions
ConditionsYield
With C54H56N8Ru(2+)*2F6P(1-); triethylamine In tetrahydrofuran at 60℃; for 16h; Inert atmosphere; Schlenk technique; Sealed tube; enantioselective reaction;99%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

Ethyl propionate
105-37-3

Ethyl propionate

1-(m-tolyl)pent-1-yn-3-one

1-(m-tolyl)pent-1-yn-3-one

Conditions
ConditionsYield
Stage #1: 1-ethynyl-3-methyl-benzene With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: Ethyl propionate With boron trifluoride diethyl etherate In tetrahydrofuran; hexane at -78℃;
99%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

4-(4-azidophenoxy)-N-methylpicolinamide

4-(4-azidophenoxy)-N-methylpicolinamide

N-methyl-4-(4-(4-(m-tolyl)-1H-1,2,3-triazol-1-yl)phenoxy)picolinamide

N-methyl-4-(4-(4-(m-tolyl)-1H-1,2,3-triazol-1-yl)phenoxy)picolinamide

Conditions
ConditionsYield
With sodium L-ascorbate In methanol at 25℃; for 16h; Inert atmosphere; Schlenk technique;99%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

1-iodo-2-((2-methylallyl)oxy)benzene
156642-47-6

1-iodo-2-((2-methylallyl)oxy)benzene

3-methyl-3-[3-(3-methylphenyl)prop-2-ynyl]-2,3-dihydro-1-benzofuran

3-methyl-3-[3-(3-methylphenyl)prop-2-ynyl]-2,3-dihydro-1-benzofuran

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate In N,N-dimethyl-formamide at 100℃; for 0.25h; Microwave irradiation; Inert atmosphere; Sealed tube; Green chemistry;99%
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 1h; Schlenk technique;95%
1,2,3,4-tetrahydroisoquinoline
91-21-4

1,2,3,4-tetrahydroisoquinoline

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

benzaldehyde
100-52-7

benzaldehyde

Conditions
ConditionsYield
In toluene at 70℃; for 12h; Inert atmosphere; Molecular sieve;99%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

1-iodo-2-((2-methylallyl)oxy)benzene
156642-47-6

1-iodo-2-((2-methylallyl)oxy)benzene

(R)-3-methyl-3-(3-(m-tolyl)prop-2-yn-1-yl)-2,3-dihydrobenzofuran

(R)-3-methyl-3-(3-(m-tolyl)prop-2-yn-1-yl)-2,3-dihydrobenzofuran

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; potassium phosphate; (R)-N-((S)-(3,5-di-tert-butyl-4-methoxyphenyl)(2-(dicyclohexylphosphanyl)phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide In ethyl acetate at 80℃; Inert atmosphere; Sealed tube; enantioselective reaction;99%

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

ethyl (E)-2,2-difluoro-4-iodo-4-(m-tolyl)but-3-enoate

ethyl (E)-2,2-difluoro-4-iodo-4-(m-tolyl)but-3-enoate

Conditions
ConditionsYield
With diethylzinc In hexane; acetonitrile at -20℃; for 16h; Schlenk technique; Inert atmosphere; stereoselective reaction;99%
With dimanganese decacarbonyl In cyclohexane at 20℃; for 1h; Schlenk technique; Irradiation;95%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

3,3″-dimethyl-4'-(m-tolyl)-1,1':2′,1″-terphenyl

3,3″-dimethyl-4'-(m-tolyl)-1,1':2′,1″-terphenyl

Conditions
ConditionsYield
With 9,10-diphenylanthracene; N-ethyl-N,N-diisopropylamine; iron(II) chloride In acetonitrile for 1h; Sealed tube; Irradiation; regioselective reaction;99%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

rac-(4,4-dimethyl-2-(m-tolyl)cyclopent-2-en-1-yl)(o-tolyl)methanone

rac-(4,4-dimethyl-2-(m-tolyl)cyclopent-2-en-1-yl)(o-tolyl)methanone

Conditions
ConditionsYield
With samarium diiodide In tetrahydrofuran at 55℃; for 0.75h; Inert atmosphere;99%
1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

benzyl azide
622-79-7

benzyl azide

1-benzyl-4-(3-methylphenyl)-1H-1,2,3-triazole
1044501-72-5

1-benzyl-4-(3-methylphenyl)-1H-1,2,3-triazole

Conditions
ConditionsYield
With Cu/Fe In dichloromethane at 30℃; for 8h;98%
With porous cross-linked polymer-phenanthroline-supported copper catalyst In water at 20℃; for 0.666667h; Huisgen Cycloaddition;98%
With (1,3-bis(2,6-dimethylphenyl)thiourea)Cu(Cl)(1,3-bis(2,6-dimethylphenyl)thiourea) In neat (no solvent) at 20℃; for 1.5h;98%
Cyclohexyl isocyanide
931-53-3

Cyclohexyl isocyanide

1-ethynyl-3-methyl-benzene
766-82-5

1-ethynyl-3-methyl-benzene

(Z)-N-(3-m-tolylprop-2-ynylidene)cyclohexanamine
1114547-94-2

(Z)-N-(3-m-tolylprop-2-ynylidene)cyclohexanamine

Conditions
ConditionsYield
With C29H51NO2Si2Y In benzene at 20℃; for 2h; Inert atmosphere; stereoselective reaction;98%

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