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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------

High purity 78-38-6 Diethyl ethylphosphonate

Cas:78-38-6

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Diethyl ethylphosphonate

Cas:78-38-6

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Ethanephosphonic acid diethyl ester

Cas:78-38-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.

TIANFU CHEM DIETHYL ETHYLPHOSPHONATE

Cas:78-38-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

78-38-6 DIETHYL ETHYLPHOSPHONATE

Cas:78-38-6

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 78-38-6 with competitive price

Cas:78-38-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Chemical Name: Diethyl Ethyl Phosphonate Synonyms: Flame Retardant DEEP CAS NO.:78-38-6 Molecular formula: C6H15O3P Introduction and Application Flame retardant DEEP is a new highly efficient organic phosphorous flame retardant, it can

DEEP Flame Retardant 78-38-6

Cas:78-38-6

Min.Order:2 Metric Ton

FOB Price: $1.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Phosphonic acid,P-ethyl-, diethyl ester 78-38-6

Cas:78-38-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

DIETHYL ETHYLPHOSPHONATE CAS: 78-38-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic in

DIETHYL ETHYLPHOSPHONATE CAS: 78-38-6

Cas:78-38-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

DEEP Flame Retardant 78-38-6

Cas:78-38-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

DEEP Flame Retardant CAS NO.78-38-6

Cas:78-38-6

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:78-38-6

Cas:78-38-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

DIETHYL ETHYLPHOSPHONATE

Cas:78-38-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Phosphonic acid,P-ethyl-, diethyl ester

Cas:78-38-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

DEEP Flame Retardant

Cas:78-38-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Diethyl ethylphosphonate

Cas:78-38-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Luyunjia Chemistry Xiamen Limited

HK Luyunjia Chemical Industry Co.,Ltd is a high-tech company specializing in R&D and manufacturing of photoinitiators monomers and oligomers, UV absorbers and pharmaceutical intermediates, and pharmaceutical intermediates of generic drug. and

Diethyl ethylphosphonate

Cas:78-38-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Best price\High Quality Diethyl ethylphosphonate CAS NO.78-38-6 CAS NO.78-38-6

Cas:78-38-6

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Diethyl ethanephosphonate cas no. 78-38-6 98%

Cas:78-38-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Diethyl ethylphosphonate

Cas:78-38-6

Min.Order:0

Negotiable

Type:Other

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Phosphonic acid,P-ethyl-, diethyl ester

Cas:78-38-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

Diethyl ethylphosphonate CAS No.78-38-6

Cas:78-38-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

DIETHYL ETHYLPHOSPHONATE

Cas:78-38-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

Diethyl ethylphosphonate cas 78-38-6Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Diethyl ethylphosphonate cas 78-38-6

Cas:78-38-6

Min.Order:0

Negotiable

Type:Other

inquiry

Wuhan ZeShanCheng Biomedical Technology Co., Ltd.

we produce and sell good chemicals around the world.Appearance:white power Storage:Keep it in dry,shady and cool place Package:as your requirement Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:SEA OR AIR Port:China Main Po

Diethyl Ethyl Phosphonate

Cas:78-38-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

DIETHYL ETHYLPHOSPHONATE

Cas:78-38-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

78-38-6

Cas:78-38-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

SAGECHEM LIMITED

78-38-6 Application:intermediate

Ethyl Diethylphosphate

Cas:78-38-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

DIETHYL ETHYLPHOSPHONATE

Cas:78-38-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

DIETHYL ETHYLPHOSPHONATE

Cas:78-38-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

ethyl bromide
74-96-4

ethyl bromide

triethyl phosphite
122-52-1

triethyl phosphite

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
at 180 - 200℃; for 0.416667h; Michaelis-Arbuzov reaction; microwave irradiation;100%
at 100℃; for 12h; reaction de Michaelis Arbuzov'a;95%
for 24h; Michaelis-Arbuzov Synthesis; Reflux;80%
In neat (no solvent) at 150℃; for 0.833333h; Temperature; Arbuzov Reaction; Flow reactor;5%
at 150℃; for 4h; Arbuzov Reaction;
ethyl iodide
75-03-6

ethyl iodide

triethyl phosphite
122-52-1

triethyl phosphite

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
In neat (no solvent) at 150℃; for 0.833333h; Temperature; Arbuzov Reaction; Flow reactor;99%
for 3h; Heating;98%
for 3h; Reflux;98%
(bromomethyl)pentafluorobenzene
1765-40-8

(bromomethyl)pentafluorobenzene

triethyl phosphite
122-52-1

triethyl phosphite

A

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

B

2,3,4,5,6-pentafluorobenzylphosphonic acid ethyl ester

2,3,4,5,6-pentafluorobenzylphosphonic acid ethyl ester

Conditions
ConditionsYield
at 160℃; for 12h;A n/a
B 99%
benzyl bromide
100-39-0

benzyl bromide

triethyl phosphite
122-52-1

triethyl phosphite

A

ethyl bromide
74-96-4

ethyl bromide

B

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

C

O,O-diethyl benzylphosphonate
1080-32-6

O,O-diethyl benzylphosphonate

Conditions
ConditionsYield
at 140℃; for 0.25h; Michaelis-Arbuzov reaction; microwave irradiation;A n/a
B n/a
C 98%
ethyl 4-(diethoxyphosphorylmethyl)-5-(iodomethyl)furan-3-carboxylate

ethyl 4-(diethoxyphosphorylmethyl)-5-(iodomethyl)furan-3-carboxylate

triethyl phosphite
122-52-1

triethyl phosphite

A

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

B

ethyl 4,5-bis-(diethoxyphosphorylmethyl)furan-3-carboxylate

ethyl 4,5-bis-(diethoxyphosphorylmethyl)furan-3-carboxylate

C

ethyl iodide
75-03-6

ethyl iodide

Conditions
ConditionsYield
at 90 - 170℃; for 0.166667h; Arbuzov Reaction;A n/a
B 98%
C n/a
triethyl phosphite
122-52-1

triethyl phosphite

A

diethyl sulfate
64-67-5

diethyl sulfate

B

triethyl phosphate
78-40-0

triethyl phosphate

C

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
With sulfur trioxide In dichloromethane at -78℃;A 97%
B 2%
C 1%
With sulfur trioxide In dichloromethane at -78℃;A 17%
B 55%
C 28%
ethanol
64-17-5

ethanol

Ethylphosphonic dichloride
1066-50-8

Ethylphosphonic dichloride

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
With aluminum oxide at 20℃;96%
triethyl phosphate
78-40-0

triethyl phosphate

ethyllithium
811-49-4

ethyllithium

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
In tetrahydrofuran at -78 - 0℃;95%
triethyl phosphite
122-52-1

triethyl phosphite

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
With iodine for 24h; Heating;95%
With trifluorormethanesulfonic acid at 60℃; for 16h; Reagent/catalyst; Schlenk technique; Inert atmosphere;95%
With diiodomethane at 100℃; for 120h;67%
With trimethylsilyl iodide at 80℃; Inert atmosphere;25%
With trifluorormethanesulfonic acid at 60℃; for 16h; Reagent/catalyst; Temperature; Time; Inert atmosphere;
1-bromo-hexane
111-25-1

1-bromo-hexane

triethyl phosphite
122-52-1

triethyl phosphite

A

triethyl phosphate
78-40-0

triethyl phosphate

B

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

C

diethyl hexylphosphonate
16165-66-5

diethyl hexylphosphonate

Conditions
ConditionsYield
at 170℃; for 12h; Inert atmosphere; Dean-Stark;A n/a
B n/a
C 95%
Diethyl vinylphosphonate
682-30-4

Diethyl vinylphosphonate

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
With hydrogen; montmorillonite-(OSi(OMe)2CH2CH2PPh2)x In benzene at 100℃; under 25857.4 Torr; for 22h;90%
With ammonium formate; palladium on activated charcoal In methanol for 18h; Ambient temperature;88%
With hydrogen; <((t-Bu)2PH)PdP(t-Bu)2>2 (pretreated with oxygen) In tetrahydrofuran under 760 Torr; for 24h; Ambient temperature;75%
ethanol
64-17-5

ethanol

ethylphosphonic acid
6779-09-5

ethylphosphonic acid

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
With tetrachlorosilane at 0℃;90%
Stage #1: ethylphosphonic acid With 1H-imidazole; iodine In dichloromethane at 45 - 50℃; for 0.5h; Gareg-Samuelsson reaction;
Stage #2: ethanol In dichloromethane at 45 - 50℃; for 0.75h; Gareg-Samuelsson reaction;
90%
With p-TsOH-Celite at 20℃;86%
benzyl alcohol
100-51-6

benzyl alcohol

triethyl phosphite
122-52-1

triethyl phosphite

A

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

B

O,O-diethyl benzylphosphonate
1080-32-6

O,O-diethyl benzylphosphonate

Conditions
ConditionsYield
Stage #1: benzyl alcohol; triethyl phosphite at 25℃; for 12h; Michaelis-Arbuzov Synthesis; Inert atmosphere; Schlenk technique; Sealed tube;
Stage #2: With tetra-(n-butyl)ammonium iodide In neat (no solvent) at 125℃; for 24h; Michaelis-Arbuzov Synthesis; Inert atmosphere; Schlenk technique; Sealed tube;
A 12 %Chromat.
B 90%
methyl vinyl ketone
78-94-4

methyl vinyl ketone

diethyl (2-iodoethyl)phosphonate
142778-06-1

diethyl (2-iodoethyl)phosphonate

A

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

B

diethyl 5-oxo-n-hexylphosphonate
1068-04-8

diethyl 5-oxo-n-hexylphosphonate

Conditions
ConditionsYield
With sodium tetrahydroborate; triethyl borane; tributyltin chloride In hexane; toluene at -78℃; Yields of byproduct given;A n/a
B 89%
diethyl (α-methylselenenylethyl)phosphonate
80436-45-9

diethyl (α-methylselenenylethyl)phosphonate

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride In toluene for 1h; Heating;88%
diethyl 2-bromoethylphosphonate
5324-30-1

diethyl 2-bromoethylphosphonate

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
With sodium hypophosphite; air; triethyl borane In methanol; hexane at 20℃; for 2h;87%
α-lithioethyl diethylphosphonate
91210-95-6

α-lithioethyl diethylphosphonate

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
With oxonium84%
5-deoxy-5-iodo-1,2-O-isopropylidene-3-O-methyl-α-D-xylofuranose
85426-94-4

5-deoxy-5-iodo-1,2-O-isopropylidene-3-O-methyl-α-D-xylofuranose

triethyl phosphite
122-52-1

triethyl phosphite

A

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

B

5-deoxy-5-C-(diethoxyphosphinyl)-1,2-O-isopropylidene-3-O-methyl-α-D-xylofuranose
17968-56-8

5-deoxy-5-C-(diethoxyphosphinyl)-1,2-O-isopropylidene-3-O-methyl-α-D-xylofuranose

Conditions
ConditionsYield
at 150℃; for 10h;A n/a
B 83%
-butyl vinyl ether
111-34-2

-butyl vinyl ether

Diethyl α-iodoethylphosphonate
191861-66-2

Diethyl α-iodoethylphosphonate

A

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

B

diethyl 1-methyl-3-n-butoxy-n-propylphosphonate

diethyl 1-methyl-3-n-butoxy-n-propylphosphonate

Conditions
ConditionsYield
With triethyl borane; tri-n-butyl-tin hydride In hexane; toluene at -78℃; Yields of byproduct given;A n/a
B 82%
O,O,O-triethyl phosphorothioate
126-68-1

O,O,O-triethyl phosphorothioate

A

Diethyl phosphate
598-02-7

Diethyl phosphate

B

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

C

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

Conditions
ConditionsYield
With magnesium monoperoxyphthalate hexahydrate In water at 25℃; for 24h;A 10%
B 81%
C 9%
vinyl acetate
108-05-4

vinyl acetate

diethyl (2-iodoethyl)phosphonate
142778-06-1

diethyl (2-iodoethyl)phosphonate

A

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

B

diethyl 4-acetoxy-n-butylphosphonate
32421-69-5

diethyl 4-acetoxy-n-butylphosphonate

Conditions
ConditionsYield
With sodium tetrahydroborate; triethyl borane; tributyltin chloride In hexane; toluene at -78℃; Yields of byproduct given;A n/a
B 81%
ethyl vinyl ether
109-92-2

ethyl vinyl ether

Diethyl α-iodoethylphosphonate
191861-66-2

Diethyl α-iodoethylphosphonate

A

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

B

diethyl 1-methyl-3-ethoxy-n-propylphosphonate

diethyl 1-methyl-3-ethoxy-n-propylphosphonate

Conditions
ConditionsYield
With sodium tetrahydroborate; triethyl borane; tributyltin chloride In hexane; toluene at -78℃; Yields of byproduct given;A n/a
B 81%
ethyl hydrogen ethylphosphonate
7305-61-5

ethyl hydrogen ethylphosphonate

1,1-di-ethoxyprop-1-ene
21504-43-8

1,1-di-ethoxyprop-1-ene

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
In benzene at 78℃; for 2h;80%
(+/-)-α-dimethylphosphorylethyl p-tolyl sulphide
73778-48-0

(+/-)-α-dimethylphosphorylethyl p-tolyl sulphide

n-Bu3SnH, AIBN

n-Bu3SnH, AIBN

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
In toluene for 1h; Heating;80%
2-iodochlorobenzene
615-41-8

2-iodochlorobenzene

triethyl phosphite
122-52-1

triethyl phosphite

A

triethyl phosphate
78-40-0

triethyl phosphate

B

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

C

2-Chlorphenylphosphonsaeurediethylester
28036-18-2

2-Chlorphenylphosphonsaeurediethylester

Conditions
ConditionsYield
With Pd/C (30%) at 175℃; for 12h; Inert atmosphere; Dean-Stark;A n/a
B n/a
C 80%
benzyl alcohol
100-51-6

benzyl alcohol

triethyl phosphite
122-52-1

triethyl phosphite

A

benzylphosphonic acid benzyl ethyl ester
945933-82-4

benzylphosphonic acid benzyl ethyl ester

B

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

C

O,O-diethyl benzylphosphonate
1080-32-6

O,O-diethyl benzylphosphonate

Conditions
ConditionsYield
Stage #1: benzyl alcohol; triethyl phosphite at 125℃; for 24h; Michaelis-Arbuzov Synthesis; Inert atmosphere; Schlenk technique; Sealed tube;
Stage #2: With tetra-(n-butyl)ammonium iodide In neat (no solvent) at 125℃; for 24h; Michaelis-Arbuzov Synthesis; Inert atmosphere; Schlenk technique; Sealed tube;
A 6 %Chromat.
B 9 %Chromat.
C 80%
ethanol
64-17-5

ethanol

A

triethyl phosphate
78-40-0

triethyl phosphate

B

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

C

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

Conditions
ConditionsYield
With phosphorous; CuCl2bpy3 In N,N-dimethyl-formamide at 50℃; Electrolysis;A 79.3%
B 5.4%
C 15.3%
With phosphorous; CuCl2bpy3 In acetonitrile at 50℃; Electrolysis;A 55%
B 15.5%
C 29.5%
With phosphorous; CuCl2bpy3 at 50℃; Electrolysis;A 28.5%
B 17.5%
C 16%
triethyl phosphonoformate
1474-78-8

triethyl phosphonoformate

A

triethyl phosphate
78-40-0

triethyl phosphate

B

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Conditions
ConditionsYield
at 395℃; for 8h;A 79%
B 8%
1-bromo-octane
111-83-1

1-bromo-octane

A

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

B

diethyl octylphosphonate
1068-07-1

diethyl octylphosphonate

Conditions
ConditionsYield
With 1-bromo-octane at 110℃; for 24h; Yield given;A n/a
B 79%
1-bromo-octane
111-83-1

1-bromo-octane

triethyl phosphite
122-52-1

triethyl phosphite

A

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

B

diethyl octylphosphonate
1068-07-1

diethyl octylphosphonate

Conditions
ConditionsYield
at 110℃; for 24h;A n/a
B 79%
ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

(6E,2R,3S,5S)-8-[(t-butyldimethylsilyl)oxy]-2,6-dimethyl-5-[(triisopropylsilyl)oxy]-3-[(trimethylsilyl)oxy]-6-octenal
237735-38-5

(6E,2R,3S,5S)-8-[(t-butyldimethylsilyl)oxy]-2,6-dimethyl-5-[(triisopropylsilyl)oxy]-3-[(trimethylsilyl)oxy]-6-octenal

(2E,4S,6S,7R,8RS)-1-[(t-butyldimethylsilyl)oxy]-9-(diethylphosphono)-3,7-dimethyl-4-[(triisopropylsilyl)oxy]-6-[(trimethylsilyl)oxy]-2-decaen-8-ol
237735-39-6

(2E,4S,6S,7R,8RS)-1-[(t-butyldimethylsilyl)oxy]-9-(diethylphosphono)-3,7-dimethyl-4-[(triisopropylsilyl)oxy]-6-[(trimethylsilyl)oxy]-2-decaen-8-ol

Conditions
ConditionsYield
Stage #1: ethylphosphonic acid diethyl ester With tert.-butyl lithium In tetrahydrofuran; pentane at -78℃; for 0.75h;
Stage #2: (6E,2R,3S,5S)-8-[(t-butyldimethylsilyl)oxy]-2,6-dimethyl-5-[(triisopropylsilyl)oxy]-3-[(trimethylsilyl)oxy]-6-octenal In tetrahydrofuran; pentane for 0.166667h;
100%
ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

Ethylphosphonic dichloride
1066-50-8

Ethylphosphonic dichloride

Conditions
ConditionsYield
With thionyl chloride In N,N-dimethyl-formamide at 75℃; for 90h;99.9%
With phosphorus pentachloride; trichlorophosphate at 25℃; for 24h;90%
With thionyl chloride In N,N-dimethyl-formamide at 75℃; for 24h;53%
(1R,2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-1-trimethylsilanyloxy-2-vinyl-cyclopentanecarboxylic acid methyl ester
886220-95-7

(1R,2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-1-trimethylsilanyloxy-2-vinyl-cyclopentanecarboxylic acid methyl ester

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

{2-[(1R,2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-1-trimethylsilanyloxy-2-vinyl-cyclopentyl]-1-methyl-2-oxo-ethyl}-phosphonic acid diethyl ester
886220-87-7

{2-[(1R,2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-1-trimethylsilanyloxy-2-vinyl-cyclopentyl]-1-methyl-2-oxo-ethyl}-phosphonic acid diethyl ester

Conditions
ConditionsYield
Stage #1: ethylphosphonic acid diethyl ester With n-butyllithium In tetrahydrofuran; hexane at -78℃;
Stage #2: (1R,2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-1-trimethylsilanyloxy-2-vinyl-cyclopentanecarboxylic acid methyl ester In tetrahydrofuran; hexane at 0℃; for 1h; Claisen-type condensation;
99%
4-(benzoyloxy)morpholine
5765-65-1

4-(benzoyloxy)morpholine

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

diethyl (1-morpholinoethyl)phosphonate
1582788-23-5

diethyl (1-morpholinoethyl)phosphonate

Conditions
ConditionsYield
Stage #1: ethylphosphonic acid diethyl ester With bis(2,2,6,6-tetramethyl-1-piperidyl)zinc In toluene at 20℃; for 1h;
Stage #2: 4-(benzoyloxy)morpholine With [2,2]bipyridinyl; copper dichloride In tetrahydrofuran; toluene at 20℃; for 4h; Catalytic behavior; Reagent/catalyst; Time;
99%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

(1R,2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-4-methyl-2-vinyl-cyclopentanecarboxylic acid methyl ester
666856-39-9

(1R,2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-4-methyl-2-vinyl-cyclopentanecarboxylic acid methyl ester

{2-[(1R,2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-1-trimethylsilanyloxy-2-vinyl-cyclopentyl]-1-methyl-2-oxo-ethyl}-phosphonic acid diethyl ester
886220-87-7

{2-[(1R,2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-1-trimethylsilanyloxy-2-vinyl-cyclopentyl]-1-methyl-2-oxo-ethyl}-phosphonic acid diethyl ester

Conditions
ConditionsYield
Stage #1: chloro-trimethyl-silane; (1R,2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-4-methyl-2-vinyl-cyclopentanecarboxylic acid methyl ester With 1H-imidazole; dmap at 20℃; for 2h;
Stage #2: ethylphosphonic acid diethyl ester In tetrahydrofuran at -78 - 20℃;
98%
ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

3-phenylpropanoic acid methyl ester
103-25-3

3-phenylpropanoic acid methyl ester

(1-methyl-2-oxo-4-phenylbutyl)phosphonic acid diethyl ester
1189399-12-9

(1-methyl-2-oxo-4-phenylbutyl)phosphonic acid diethyl ester

Conditions
ConditionsYield
Stage #1: ethylphosphonic acid diethyl ester; 3-phenylpropanoic acid methyl ester With lithium diisopropyl amide In tetrahydrofuran at -5 - 0℃; Inert atmosphere;
Stage #2: With hydrogenchloride In tetrahydrofuran; water pH=ca. 4;
97%
ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

C17H31BrO3Si

C17H31BrO3Si

C23H46BrO6PSi

C23H46BrO6PSi

Conditions
ConditionsYield
Stage #1: ethylphosphonic acid diethyl ester With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -78℃; for 0.5h;
Stage #2: C17H31BrO3Si In tetrahydrofuran; hexane at -78℃; for 1h;
96%
ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

A

chloroethane
75-00-3

chloroethane

B

Ethylphosphonic dichloride
1066-50-8

Ethylphosphonic dichloride

Conditions
ConditionsYield
With thionyl chloride; N,N-dimethyl-formamide for 18h; Heating;A n/a
B 95.8%
aluminum trihydroxide

aluminum trihydroxide

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

aluminum ethyl ethylphosphonate

aluminum ethyl ethylphosphonate

Conditions
ConditionsYield
With tetrabutyl phosphonium bromide at 180℃; for 20h; Reagent/catalyst; Inert atmosphere;95%
ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

methyl (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
60456-21-5

methyl (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate

diethyl (1-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-1-oxopropan-2-yl)phosphonate

diethyl (1-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-1-oxopropan-2-yl)phosphonate

Conditions
ConditionsYield
Stage #1: ethylphosphonic acid diethyl ester With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 2h;
Stage #2: methyl (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate In tetrahydrofuran; hexane for 1h;
95%
Stage #1: ethylphosphonic acid diethyl ester With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 2h;
Stage #2: methyl (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate In tetrahydrofuran; hexane for 1h;
95%
1,4-Dioxaspiro<4.4>nonan-6-essigsaeure-ethylester
82253-44-9

1,4-Dioxaspiro<4.4>nonan-6-essigsaeure-ethylester

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

diethyl 1-methyl-2-oxo-3-<2-(1,3-dioxolano)cyclopentyl>propyl phosphonate
82253-45-0

diethyl 1-methyl-2-oxo-3-<2-(1,3-dioxolano)cyclopentyl>propyl phosphonate

Conditions
ConditionsYield
Stage #1: ethylphosphonic acid diethyl ester With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.55h; Inert atmosphere;
Stage #2: 1,4-Dioxaspiro<4.4>nonan-6-essigsaeure-ethylester In tetrahydrofuran; hexane at -78 - 20℃; for 2h; Inert atmosphere;
94%
Stage #1: ethylphosphonic acid diethyl ester With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.55h;
Stage #2: 1,4-Dioxaspiro<4.4>nonan-6-essigsaeure-ethylester In tetrahydrofuran; hexane at -78 - 20℃; for 2h;
94%
With n-butyllithium 1) THF, hexane, - 78 deg C, 0.55 h, 2) THF, hexane, -78 deg C, 1 h, then warm to room temp.; Yield given. Multistep reaction;
ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

(2R,3R)-3,12-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dodecanethioic acid S-tert-butyl ester

(2R,3R)-3,12-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dodecanethioic acid S-tert-butyl ester

[(3R,4R)-4,13-Bis-(tert-butyl-dimethyl-silanyloxy)-1,3-dimethyl-2-oxo-tridecyl]-phosphonic acid diethyl ester

[(3R,4R)-4,13-Bis-(tert-butyl-dimethyl-silanyloxy)-1,3-dimethyl-2-oxo-tridecyl]-phosphonic acid diethyl ester

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane 1.) -78 deg C, 1 h, 2.) -78 deg C, 4 h;94%
ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

(2R,3R)-3,9-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methyl-nonanethioic acid S-tert-butyl ester

(2R,3R)-3,9-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methyl-nonanethioic acid S-tert-butyl ester

[(3R,4R)-4,10-Bis-(tert-butyl-dimethyl-silanyloxy)-1,3-dimethyl-2-oxo-decyl]-phosphonic acid diethyl ester

[(3R,4R)-4,10-Bis-(tert-butyl-dimethyl-silanyloxy)-1,3-dimethyl-2-oxo-decyl]-phosphonic acid diethyl ester

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran for 1h;94%
With n-butyllithium In tetrahydrofuran; hexane 1.) -78 deg C, 50 min, 2.) -78 deg C, 50 min;94%
ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

(-)-menthol
2216-51-5

(-)-menthol

ethyl (-)-menthyl ethylphosphonate
930597-00-5

ethyl (-)-menthyl ethylphosphonate

Conditions
ConditionsYield
Stage #1: (-)-menthol With n-butyllithium In tetrahydrofuran; hexane at 0℃; for 0.166667h;
Stage #2: ethylphosphonic acid diethyl ester In tetrahydrofuran; hexane at 20℃;
94%
ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

2-methyl-3-oxocyclohex-1-en-1-yl trifluoromethanesulfonate
150765-78-9

2-methyl-3-oxocyclohex-1-en-1-yl trifluoromethanesulfonate

C13H23O4P
1225212-02-1

C13H23O4P

Conditions
ConditionsYield
Stage #1: ethylphosphonic acid diethyl ester With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.333333h; Inert atmosphere;
Stage #2: 2-methyl-3-oxocyclohex-1-en-1-yl trifluoromethanesulfonate In tetrahydrofuran; hexane at -78 - 60℃; Inert atmosphere;
Stage #3: With water; ammonium chloride In tetrahydrofuran; diethyl ether; hexane Inert atmosphere;
94%
Phenylselenyl chloride
5707-04-0

Phenylselenyl chloride

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

ethyl (E)-5,9-dimethyl-4,8-decadienoate
19894-83-8

ethyl (E)-5,9-dimethyl-4,8-decadienoate

C24H37O4PSe

C24H37O4PSe

Conditions
ConditionsYield
Stage #1: ethylphosphonic acid diethyl ester; ethyl (E)-5,9-dimethyl-4,8-decadienoate With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -10℃; Inert atmosphere;
Stage #2: Phenylselenyl chloride In tetrahydrofuran; hexane at -78℃; Inert atmosphere;
93%
ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

allyl bromide
106-95-6

allyl bromide

diethyl 1-methyl-n-but-3-enylphosphonate
71071-59-5

diethyl 1-methyl-n-but-3-enylphosphonate

Conditions
ConditionsYield
Stage #1: ethylphosphonic acid diethyl ester With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Metallation;
Stage #2: allyl bromide In tetrahydrofuran at -78 - 20℃; Alkylation;
92%
(i) nBuLi, (ii) CuI, (iii) /BRN= 605308/; Multistep reaction;
With n-butyllithium 1.) THF, -78 deg C, 2.) THF, -78 to 25 deg C; Yield given. Multistep reaction;
Stage #1: ethylphosphonic acid diethyl ester With n-butyllithium In tetrahydrofuran at -78℃; Metallation;
Stage #2: allyl bromide Alkylation;
1-methyl-1H-imidazole
616-47-7

1-methyl-1H-imidazole

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

1-ethyl-3-methylimidazolium ethyl ethylphosphonate

1-ethyl-3-methylimidazolium ethyl ethylphosphonate

Conditions
ConditionsYield
at 160℃; for 11.3333h;92%
4-nitrobenzyl chloride
619-73-8

4-nitrobenzyl chloride

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

di(p-nitrobenzyl) ethylphosphonate

di(p-nitrobenzyl) ethylphosphonate

Conditions
ConditionsYield
Stage #1: ethylphosphonic acid diethyl ester With hydrogenchloride In water for 20h; Reflux;
Stage #2: 4-nitrobenzyl chloride With pyridine; 2H-tetrazole; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 18h;
92%
(2S,3S)-3-(tert-Butyl-dimethyl-silanyloxy)-2,5-dimethyl-hexanethioic acid S-{(1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl} ester
913288-93-4

(2S,3S)-3-(tert-Butyl-dimethyl-silanyloxy)-2,5-dimethyl-hexanethioic acid S-{(1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl} ester

ethylphosphonic acid diethyl ester
78-38-6

ethylphosphonic acid diethyl ester

[(3S,4S)-4-(tert-Butyl-dimethyl-silanyloxy)-1,3,6-trimethyl-2-oxo-heptyl]-phosphonic acid diethyl ester

[(3S,4S)-4-(tert-Butyl-dimethyl-silanyloxy)-1,3,6-trimethyl-2-oxo-heptyl]-phosphonic acid diethyl ester

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane at -78℃;91%

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