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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Butanoic acid,4-hydroxy-, ethyl ester

Cas:999-10-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Ethyl 4-hydroxybutanoate CAS:999-10-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic in

Ethyl 4-hydroxybutanoate CAS:999-10-0

Cas:999-10-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Butanoic acid,4-hydroxy-, ethyl ester

Cas:999-10-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Butanoic acid,4-hydroxy-, ethyl ester

Cas:999-10-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: Ethyl 4-hydroxybutanoate Synonyms: ethylhydroxybutanoate,ethyl4-hydroxybutanoate;4-Hydroxybutanoic acid ethyl ester;Ethyl 4-hydroxybutanoate;Ethyl 4-hydroxybutyrate;4-Hydroxybutyric acid ethyl ester;Butanoic acid, 4-hydroxy-, ethy

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Butanoic acid,4-hydroxy-, ethyl ester

Cas:999-10-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Butanoic acid,4-hydroxy-, ethyl ester

Cas:999-10-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary a

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Ethyl 4-hydroxybutanoateAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea, by express

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:0

Negotiable

Type:Other

inquiry

Shandong Mopai Biotechnology Co., LTD

best seller Application:API

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

999-10-0

Cas:999-10-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

999-10-0 C6H12O3 Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

999-10-0 C6H12O3 Ethyl 4-hydroxybutanoate CAS NO.999-10-0

Cas:999-10-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Yinghao Pharm Co.,Ltd.

Yinghao Pharm products include: leader molecule, heterocyclic compounds,chiral compounds, photoelectric materials, biochemical reagents etc. For example:benzene, pyrimidine, boricacid,pyridine, pyrazole, imidazole, pyrrole, fluorine and other derivat

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zouping Mingxing Chemical Co.,Ltd.

Appearance:standard Storage:dry,cool Package:UN Drum Transportation:by sea or air

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chungking Joyinchem Co., Ltd.

Joyinchem have been committed to chemical supply for several years and have built good cooperation records with multinational chemical corporations and importers from all over the world. Our services include:-Spot goods-Contract manufacturing-Custom

Butanoic acid,4-hydroxy-, ethyl ester

Cas:999-10-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Chemlin Chemical Co., Ltd.

please contact us to confirm the required quantity and quote, we will provide you with COA,NMR,HPLC and other relevant informationAppearance:Colorless liquid Storage:Store in a cool place. Keep container tightly closed in a dry and well-ventilated pl

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai united Scientific Co.,Ltd.

Butanoic acid,4-hydroxy-, ethyl ester

Cas:999-10-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

NovaChemistry

high purity Application:Drug intermediates Materials intermediates and active molecules

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Aldlab Chemicals, LLC

Ethyl 4-hydroxybutanoate

Cas:999-10-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

4-butanolide
96-48-0

4-butanolide

ethanol
64-17-5

ethanol

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With amberlyst-15 for 20h;94%
With sulfuric acid Ambient temperature;80%
With sulfuric acid at 20℃; for 33h;55%
4-isopropoxycarbonyloxy-butyric acid ethyl ester

4-isopropoxycarbonyloxy-butyric acid ethyl ester

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With aluminium trichloride In nitromethane at 25℃; for 3h;86%
3-acetyl-2-oxo-4,5-dihydrofuran
517-23-7

3-acetyl-2-oxo-4,5-dihydrofuran

A

4-butanolide
96-48-0

4-butanolide

B

5-Hydroxy-2-pentanone
1071-73-4

5-Hydroxy-2-pentanone

C

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

D

ethyl 4-(acetyloxy)butanoate
25560-91-2

ethyl 4-(acetyloxy)butanoate

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water at 200℃; for 2h;A 75%
B 5%
C 8%
D 12%
With sodium hydroxide In ethanol; water at 200℃; for 2h;A 75%
B 3%
C 8%
D 12%
With sodium hydroxide In ethanol; water at 200℃; for 2h; Product distribution; other reagent/educt ratio,;A 15%
B 16%
C 4%
D 62%
With sodium hydroxide In ethanol; water at 200℃; for 2h;A 15%
B 16%
C 4%
D 62%
4-bromoethylbutanoate
2969-81-5

4-bromoethylbutanoate

A

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

B

ethyl cyclopropylcarboxylate
4606-07-9

ethyl cyclopropylcarboxylate

Conditions
ConditionsYield
With oxygen; tetraethylammonium perchlorate In N,N-dimethyl-formamide at 20℃; electroreduction at -1.1 V;A 10%
B 68%
4-butanolide
96-48-0

4-butanolide

ethyl acetate
141-78-6

ethyl acetate

A

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

B

ethyl 4-(acetyloxy)butanoate
25560-91-2

ethyl 4-(acetyloxy)butanoate

C

ethyl 2-acetyl-4-acetoxybutyrate
87418-30-2

ethyl 2-acetyl-4-acetoxybutyrate

Conditions
ConditionsYield
With sodium ethanolate at -50℃;A 9%
B 57%
C 25%
diethyl 2-ketoglutarate
5965-53-7

diethyl 2-ketoglutarate

A

(–)-(S)-diethyl 2-hydroxyglutarate
55094-99-0

(–)-(S)-diethyl 2-hydroxyglutarate

B

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With baker's yeast Ambient temperature;A 18%
B 34%
4-butanolide
96-48-0

4-butanolide

triethyloxonium fluoroborate
368-39-8

triethyloxonium fluoroborate

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
(i) aq. NaOH, (ii) /BRN= 3598090/, MeCN; Multistep reaction;
3,3-Bis-ethylsulfanylcarbonyl-propionic acid ethyl ester
72291-79-3

3,3-Bis-ethylsulfanylcarbonyl-propionic acid ethyl ester

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
nickel
4-butanolide
96-48-0

4-butanolide

sodium ethanolate
141-52-6

sodium ethanolate

ethyl acetate
141-78-6

ethyl acetate

A

3-acetyl-2-oxo-4,5-dihydrofuran
517-23-7

3-acetyl-2-oxo-4,5-dihydrofuran

B

5-Hydroxy-2-pentanone
1071-73-4

5-Hydroxy-2-pentanone

C

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

D

ethyl 4-(acetyloxy)butanoate
25560-91-2

ethyl 4-(acetyloxy)butanoate

E

ethyl acetoacetate
141-97-9

ethyl acetoacetate

F

α-(2-Tetrahydrofuranylidene)-γ-butyrolactone
65652-24-6

α-(2-Tetrahydrofuranylidene)-γ-butyrolactone

Conditions
ConditionsYield
at 100℃; under 1064 Torr; for 0.5h; Product distribution; various molar ratio of the reagents, other temp., other pressure, other time;
4-bromoethylbutanoate
2969-81-5

4-bromoethylbutanoate

A

4-butanolide
96-48-0

4-butanolide

B

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With water; triethylamine In ethanol at 120.1℃; Kinetics; further temperatures, further solvent, activation enthalpy and entropy;
ethyl 4-oxobutanoate
10138-10-0

ethyl 4-oxobutanoate

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With glycerol dehydrogenase; 2-propanol-NAD(1+) potassium phosphate buffer, pH 7;
4-butanolide
96-48-0

4-butanolide

ethanol
64-17-5

ethanol

sulfuric acid
7664-93-9

sulfuric acid

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
bei Raumtemperatur;
succinic acid diethyl ester
123-25-1

succinic acid diethyl ester

copper-chromium oxide

copper-chromium oxide

A

4-butanolide
96-48-0

4-butanolide

B

Butane-1,4-diol
110-63-4

Butane-1,4-diol

C

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

D

butyric acid
107-92-6

butyric acid

Conditions
ConditionsYield
at 250℃; under 220652 Torr; Produkt 5: Tetrahydrofuran(?).Hydrogenation;
at 250℃; under 220652 Torr; Produkt 5: Tetrahydrofuran(?).Hydrogenation;
hydrochloride of γ-amino-butyric acid ethyl ester

hydrochloride of γ-amino-butyric acid ethyl ester

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With sodium nitrite
ethyl γ-aminobutyrate hydrochloride
6937-16-2

ethyl γ-aminobutyrate hydrochloride

NaNO2

NaNO2

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

ethanol
64-17-5

ethanol

thiosuccinic acid O-ethyl ester-S-benzyl ester
108881-52-3

thiosuccinic acid O-ethyl ester-S-benzyl ester

Raney nickel

Raney nickel

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

4-ethoxybut-3-ynyloxy-tert-butyl-diphenylsilane
112793-76-7

4-ethoxybut-3-ynyloxy-tert-butyl-diphenylsilane

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
Acid hydrolysis;
1-ethoxy-1-butyn-4-ol
19985-85-4

1-ethoxy-1-butyn-4-ol

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 553 mg / imidazole / CH2Cl2 / 1.5 h
2: Acid hydrolysis
View Scheme
2-ethoxytetrahydrofuran
13436-46-9

2-ethoxytetrahydrofuran

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With ozone for 8h; Ionic liquid;
4-butanolide
96-48-0

4-butanolide

ethanol
64-17-5

ethanol

sodium ethanolate
141-52-6

sodium ethanolate

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
at 20℃; for 48h;
4-butanolide
96-48-0

4-butanolide

ethanol
64-17-5

ethanol

A

Butane-1,4-diol
110-63-4

Butane-1,4-diol

B

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With hydrogen at 100℃; under 25502.6 Torr; for 24h; Reagent/catalyst; Solvent; Autoclave;
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

ortho-cresol
95-48-7

ortho-cresol

4-o-tolyloxybutyric acid ethyl ester
56359-11-6

4-o-tolyloxybutyric acid ethyl ester

Conditions
ConditionsYield
With Si-Al supported catalyst at 90℃; for 1h;97.7%
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

4-{[(1R,2S)-2-methylcyclopentyl]amino}-2-(methylsulfanyl)pyrimidine-5-carbaldehyde

4-{[(1R,2S)-2-methylcyclopentyl]amino}-2-(methylsulfanyl)pyrimidine-5-carbaldehyde

6-(2-hydroxyethyl)-8-[(1R,2S)-2-methylcyclopentyl]-2-(methylsulfanyl)pyrido[2,3-d]pyrimidin-7(8H)-one

6-(2-hydroxyethyl)-8-[(1R,2S)-2-methylcyclopentyl]-2-(methylsulfanyl)pyrido[2,3-d]pyrimidin-7(8H)-one

Conditions
ConditionsYield
Stage #1: ethyl 4-hydroxybutanoate With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.333333h;
Stage #2: 4-{[(1R,2S)-2-methylcyclopentyl]amino}-2-(methylsulfanyl)pyrimidine-5-carbaldehyde In tetrahydrofuran at 20℃; for 18h;
95%
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

4-(p-toluenesulfonyloxy)butyric acid ethyl ester

4-(p-toluenesulfonyloxy)butyric acid ethyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 5 - 20℃; for 6h;92%
With triethylamine In diethyl ether at 0℃; for 2h;72%
With triethylamine at 0℃; for 2h;
With dmap; triethylamine In dichloromethane
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

benzylamine
100-46-9

benzylamine

N-benzyl-4-hydroxybutanamide
19340-88-6

N-benzyl-4-hydroxybutanamide

Conditions
ConditionsYield
With 1-(3-sulfopropyl)pyridinium phosphotungstate In neat (no solvent) at 100℃; for 0.5h; Microwave irradiation;90%
diazoacetic acid ethyl ester
623-73-4

diazoacetic acid ethyl ester

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

4-ethoxycarbonylmethoxy-butyric acid ethyl ester
388109-23-7

4-ethoxycarbonylmethoxy-butyric acid ethyl ester

Conditions
ConditionsYield
dirhodium tetraacetate In dichloromethane at 20℃; for 73.5h;87%
rhodium(II) acetate In dichloromethane at 20℃; for 73.5h;87%
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

4-phosphonooxy-butyric acid ethyl ester
98275-36-6

4-phosphonooxy-butyric acid ethyl ester

Conditions
ConditionsYield
With PPA
4-butanolide
96-48-0

4-butanolide

ethanol
64-17-5

ethanol

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With amberlyst-15 for 20h;94%
With sulfuric acid Ambient temperature;80%
With sulfuric acid at 20℃; for 33h;55%
4-isopropoxycarbonyloxy-butyric acid ethyl ester

4-isopropoxycarbonyloxy-butyric acid ethyl ester

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With aluminium trichloride In nitromethane at 25℃; for 3h;86%
3-acetyl-2-oxo-4,5-dihydrofuran
517-23-7

3-acetyl-2-oxo-4,5-dihydrofuran

A

4-butanolide
96-48-0

4-butanolide

B

5-Hydroxy-2-pentanone
1071-73-4

5-Hydroxy-2-pentanone

C

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

D

ethyl 4-(acetyloxy)butanoate
25560-91-2

ethyl 4-(acetyloxy)butanoate

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water at 200℃; for 2h;A 75%
B 5%
C 8%
D 12%
With sodium hydroxide In ethanol; water at 200℃; for 2h;A 75%
B 3%
C 8%
D 12%
With sodium hydroxide In ethanol; water at 200℃; for 2h; Product distribution; other reagent/educt ratio,;A 15%
B 16%
C 4%
D 62%
With sodium hydroxide In ethanol; water at 200℃; for 2h;A 15%
B 16%
C 4%
D 62%
4-bromoethylbutanoate
2969-81-5

4-bromoethylbutanoate

A

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

B

ethyl cyclopropylcarboxylate
4606-07-9

ethyl cyclopropylcarboxylate

Conditions
ConditionsYield
With oxygen; tetraethylammonium perchlorate In N,N-dimethyl-formamide at 20℃; electroreduction at -1.1 V;A 10%
B 68%
4-butanolide
96-48-0

4-butanolide

ethyl acetate
141-78-6

ethyl acetate

A

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

B

ethyl 4-(acetyloxy)butanoate
25560-91-2

ethyl 4-(acetyloxy)butanoate

C

ethyl 2-acetyl-4-acetoxybutyrate
87418-30-2

ethyl 2-acetyl-4-acetoxybutyrate

Conditions
ConditionsYield
With sodium ethanolate at -50℃;A 9%
B 57%
C 25%
diethyl 2-ketoglutarate
5965-53-7

diethyl 2-ketoglutarate

A

(–)-(S)-diethyl 2-hydroxyglutarate
55094-99-0

(–)-(S)-diethyl 2-hydroxyglutarate

B

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With baker's yeast Ambient temperature;A 18%
B 34%
4-butanolide
96-48-0

4-butanolide

triethyloxonium fluoroborate
368-39-8

triethyloxonium fluoroborate

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
(i) aq. NaOH, (ii) /BRN= 3598090/, MeCN; Multistep reaction;
3,3-Bis-ethylsulfanylcarbonyl-propionic acid ethyl ester
72291-79-3

3,3-Bis-ethylsulfanylcarbonyl-propionic acid ethyl ester

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
nickel
4-butanolide
96-48-0

4-butanolide

sodium ethanolate
141-52-6

sodium ethanolate

ethyl acetate
141-78-6

ethyl acetate

A

3-acetyl-2-oxo-4,5-dihydrofuran
517-23-7

3-acetyl-2-oxo-4,5-dihydrofuran

B

5-Hydroxy-2-pentanone
1071-73-4

5-Hydroxy-2-pentanone

C

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

D

ethyl 4-(acetyloxy)butanoate
25560-91-2

ethyl 4-(acetyloxy)butanoate

E

ethyl acetoacetate
141-97-9

ethyl acetoacetate

F

α-(2-Tetrahydrofuranylidene)-γ-butyrolactone
65652-24-6

α-(2-Tetrahydrofuranylidene)-γ-butyrolactone

Conditions
ConditionsYield
at 100℃; under 1064 Torr; for 0.5h; Product distribution; various molar ratio of the reagents, other temp., other pressure, other time;
4-bromoethylbutanoate
2969-81-5

4-bromoethylbutanoate

A

4-butanolide
96-48-0

4-butanolide

B

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With water; triethylamine In ethanol at 120.1℃; Kinetics; further temperatures, further solvent, activation enthalpy and entropy;
ethyl 4-oxobutanoate
10138-10-0

ethyl 4-oxobutanoate

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With glycerol dehydrogenase; 2-propanol-NAD(1+) potassium phosphate buffer, pH 7;
4-butanolide
96-48-0

4-butanolide

ethanol
64-17-5

ethanol

sulfuric acid
7664-93-9

sulfuric acid

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
bei Raumtemperatur;
succinic acid diethyl ester
123-25-1

succinic acid diethyl ester

copper-chromium oxide

copper-chromium oxide

A

4-butanolide
96-48-0

4-butanolide

B

Butane-1,4-diol
110-63-4

Butane-1,4-diol

C

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

D

butyric acid
107-92-6

butyric acid

Conditions
ConditionsYield
at 250℃; under 220652 Torr; Produkt 5: Tetrahydrofuran(?).Hydrogenation;
at 250℃; under 220652 Torr; Produkt 5: Tetrahydrofuran(?).Hydrogenation;
hydrochloride of γ-amino-butyric acid ethyl ester

hydrochloride of γ-amino-butyric acid ethyl ester

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With sodium nitrite
ethyl γ-aminobutyrate hydrochloride
6937-16-2

ethyl γ-aminobutyrate hydrochloride

NaNO2

NaNO2

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

ethanol
64-17-5

ethanol

thiosuccinic acid O-ethyl ester-S-benzyl ester
108881-52-3

thiosuccinic acid O-ethyl ester-S-benzyl ester

Raney nickel

Raney nickel

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

4-ethoxybut-3-ynyloxy-tert-butyl-diphenylsilane
112793-76-7

4-ethoxybut-3-ynyloxy-tert-butyl-diphenylsilane

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
Acid hydrolysis;
1-ethoxy-1-butyn-4-ol
19985-85-4

1-ethoxy-1-butyn-4-ol

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 553 mg / imidazole / CH2Cl2 / 1.5 h
2: Acid hydrolysis
View Scheme
2-ethoxytetrahydrofuran
13436-46-9

2-ethoxytetrahydrofuran

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With ozone for 8h; Ionic liquid;
4-butanolide
96-48-0

4-butanolide

ethanol
64-17-5

ethanol

sodium ethanolate
141-52-6

sodium ethanolate

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
at 20℃; for 48h;
4-butanolide
96-48-0

4-butanolide

ethanol
64-17-5

ethanol

A

Butane-1,4-diol
110-63-4

Butane-1,4-diol

B

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

Conditions
ConditionsYield
With hydrogen at 100℃; under 25502.6 Torr; for 24h; Reagent/catalyst; Solvent; Autoclave;
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

ortho-cresol
95-48-7

ortho-cresol

4-o-tolyloxybutyric acid ethyl ester
56359-11-6

4-o-tolyloxybutyric acid ethyl ester

Conditions
ConditionsYield
With Si-Al supported catalyst at 90℃; for 1h;97.7%
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

4-{[(1R,2S)-2-methylcyclopentyl]amino}-2-(methylsulfanyl)pyrimidine-5-carbaldehyde

4-{[(1R,2S)-2-methylcyclopentyl]amino}-2-(methylsulfanyl)pyrimidine-5-carbaldehyde

6-(2-hydroxyethyl)-8-[(1R,2S)-2-methylcyclopentyl]-2-(methylsulfanyl)pyrido[2,3-d]pyrimidin-7(8H)-one

6-(2-hydroxyethyl)-8-[(1R,2S)-2-methylcyclopentyl]-2-(methylsulfanyl)pyrido[2,3-d]pyrimidin-7(8H)-one

Conditions
ConditionsYield
Stage #1: ethyl 4-hydroxybutanoate With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.333333h;
Stage #2: 4-{[(1R,2S)-2-methylcyclopentyl]amino}-2-(methylsulfanyl)pyrimidine-5-carbaldehyde In tetrahydrofuran at 20℃; for 18h;
95%
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

4-(p-toluenesulfonyloxy)butyric acid ethyl ester

4-(p-toluenesulfonyloxy)butyric acid ethyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 5 - 20℃; for 6h;92%
With triethylamine In diethyl ether at 0℃; for 2h;72%
With triethylamine at 0℃; for 2h;
With dmap; triethylamine In dichloromethane
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

benzylamine
100-46-9

benzylamine

N-benzyl-4-hydroxybutanamide
19340-88-6

N-benzyl-4-hydroxybutanamide

Conditions
ConditionsYield
With 1-(3-sulfopropyl)pyridinium phosphotungstate In neat (no solvent) at 100℃; for 0.5h; Microwave irradiation;90%
diazoacetic acid ethyl ester
623-73-4

diazoacetic acid ethyl ester

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

4-ethoxycarbonylmethoxy-butyric acid ethyl ester
388109-23-7

4-ethoxycarbonylmethoxy-butyric acid ethyl ester

Conditions
ConditionsYield
dirhodium tetraacetate In dichloromethane at 20℃; for 73.5h;87%
rhodium(II) acetate In dichloromethane at 20℃; for 73.5h;87%
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

N-(4-methoxybenzyl)-2,2,2-trichloroacetamide
123558-64-5

N-(4-methoxybenzyl)-2,2,2-trichloroacetamide

ethyl 4-((4-metoxybenzyl)oxy)butanoate

ethyl 4-((4-metoxybenzyl)oxy)butanoate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In dichloromethane; cyclohexane86%
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

ethyl 4-(t-butyldimethylsiloxy)butanoate
506417-45-4

ethyl 4-(t-butyldimethylsiloxy)butanoate

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 20℃;85%
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

ethyl 4-oxobutanoate
10138-10-0

ethyl 4-oxobutanoate

Conditions
ConditionsYield
With oxalyl dichloride; dimethyl sulfoxide; triethylamine In dichloromethane at -78 - 0℃; for 2.16667h; Swern Oxidation; Inert atmosphere;82%
With sodium acetate; pyridinium chlorochromate In dichloromethane for 2h;79%
With dipyridinium dichromate In dichloromethane for 48h; Ambient temperature;63%
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

2-monochlorophenol
95-57-8

2-monochlorophenol

ethyl 4-(2-chlorophenoxy)butanoate
111105-19-2

ethyl 4-(2-chlorophenoxy)butanoate

Conditions
ConditionsYield
With ceramic and V-supported catalyst (active component: carrier mass ratio of 10:100) at 110 - 140℃; for 5h;39.13%
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

4-phosphonooxy-butyric acid ethyl ester
98275-36-6

4-phosphonooxy-butyric acid ethyl ester

Conditions
ConditionsYield
With PPA
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

4-(Tetrahydro-pyran-2-yloxy)-butyric acid ethyl ester
117745-48-9

4-(Tetrahydro-pyran-2-yloxy)-butyric acid ethyl ester

Conditions
ConditionsYield
With hydrogenchloride
ethyl 4-hydroxybutanoate
999-10-0

ethyl 4-hydroxybutanoate

3'-O-methylthiomethyl-5'-pivaloylthymidine

3'-O-methylthiomethyl-5'-pivaloylthymidine

4-[(2R,3S,4R,5R)-2-(2,2-Dimethyl-propionyloxymethyl)-4-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yloxymethoxy]-butyric acid ethyl ester

4-[(2R,3S,4R,5R)-2-(2,2-Dimethyl-propionyloxymethyl)-4-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yloxymethoxy]-butyric acid ethyl ester

Conditions
ConditionsYield
With N-Bromosuccinimide; lutidine 1.) dichloromethane, 2.) dichloromethane; Yield given. Multistep reaction;

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