2-hydroxypyridine synthesis, Hot sale 2-Hydroxypyridine(CAS:142-08-5), 2-pyridone

Beijing Wisdom Chemicals Co., Ltd.

Country:China (Mainland)

Year Established: 1999Business type: Manufacturers

Integral:

1. Introduction of 2-hydroxypyridine

2-hydroxypyridine (CAS NO.142-08-5) is a organic chemical and shows the appearance of similar white to slight yellow crystal or white powder. 2-pyridone is another name of this product. This colourless crystalline solid is used in peptide synthesis. 2-hydroxypyridine is well known to form hydrogen bonded structures somewhat related to the base-pairing mechanism found in RNA and DNA. Hot sale 2-Hydroxypyridine(CAS:142-08-5) is also a classic case of a molecule that exists as tautomers.

2-Pyridone is not naturally occurring, but a derivative has been isolated as a cofactor in certain hydrogenases. Hot sale 2-Hydroxypyridine(CAS:142-08-5) is used as a pharmaceutical intermediate and for Fine Organic Synthesis.

2. 2-hydroxypyridine synthesis

(1) 2-hydroxypyridine can be obtained by a cyclisation reaction and converted to 2-pyridone via an exchange reaction with ammonia:

the synthesis of 2-Pyrone

(2) In the Guareschi-Thorpe condensation cyanoacetamide reacts with a 1,3-diketone to a 2-pyridone.

(3) Pyridine forms an N-oxide with some oxidation agents such as hydrogen peroxide. This pyridine-N-oxide undergoes a rearrangement reaction to 2-pyridone in acetic anhydride, then you can obtain the 2-hydroxypyridine:

from the N-oxide to 2-hydroxypyridine

We are in the Fine Chemical Market since 10 years. WISDOMCHEM consists of four companies that include one trading company, two sites and one research center. Beijing Wisdom Chemicals Co., Ltd is the headquarter of WISDOMCHEM, responsible for trading and administrating. WISDOMCHEM has 2 sites, one in Tianjin Jixian Economic and Technologic Development Zone located 90km East of Beijing and mainly specialized in production of m-Bromoanisole (MBA), Cyclopropyl Bromide, 2-Methyl-3-trifluoromethylanline (MTA) and 2,3,4-Trimethoxybenzaldehyde (TMBA); one in Yongqing Hebei Province located 70km South of Beijing and specialized in production of 2-Hydroxypyridine, 3-Nitro-4-methylaniline, Pyridine derivatives, API intermediates and other new development projects from pilot plant to large industrial scale. WISDOMCHEM has one research center, Beijing SSK Pharmaceutical Technology Development, which located together with Beijing Wisdom Chemicals in Beijing, and focused on process development & optimization. WISDOMCHEM provides its customers world-class pharmaceutical intermediates and fine chemical raw materials. We are experts in industrial development and manufacturing of chemicals from R&D grams to multi tons production. Our greatest assets are our people and their passion for excellence. We promise to our customers: excellent products, perfect services and competitive prices.

Basic Information

Company Name：Beijing Wisdom Chemicals Co., Ltd.
Number of Employees：101 - 500
Contact person：Wilson Qu
Street Address：F2, BLDG 19, Liando Valley U, Majuqiao, Tongzhou District, Beijing, China
City：Beijing
Province/State：Beijing
Country/Region：China (Mainland)
Zip：101102
Business type：Manufacturers
Tel：+86-10-52350335
Fax：+86-10-52350375
Website：
Year Established：1999