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NANJING AILY BIOTECHNOLOGY CO.,LTD

Country:China (Mainland)

Year Established: Business type: Lab/Research institutions

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 AZTREONAM - only has activity vs. aerobic gram negatives, no gram positive or anaerobes = very similar coverage as Aminoglycosides. Used most often in PCN allergic patients. Almost no significant toxicity.
- main advantages:1) No cross-reactivity with PCN allergy, and 2) Does not cause renal failure
- Has similar side chain as Ceftazidime – if Ceftaz allergy, avoid Aztreonam!


Inhaled aztreonam, a newly formulated lysine salt of the original monobactam antibiotic, is approved for the treatment of respiratory symptoms in patients with cystic fibrosis (CF) who are colonized with Pseudomonas aeruginosa.

 

Aztreonam belongs to a class of drugs known as beta-lactams. Aztreonam inhalation solution works by stopping the growth of a certain bacteria (Pseudomonas aeruginosa) that commonly infects the lungs of people with cystic fibrosis. This effect decreases lung infections and damage, decreases the use of other antibiotics, and helps to improve breathing.

 

Before treatment with inhaled aztreonam, you should inhale a bronchodilator (such as albuterol, formoterol, salmeterol). Ask your pharmacist or doctor how soon to pre-treat with the specific bronchodilator you are using.

 

Use this medication with the nebulizer as directed by your doctor, usually three times a day. Each treatment lasts about 2 to 3 minutes. Do not swallow or inject this medication. This medicine is usually used for 28 days in a row, followed by 28 days without this medication, repeating the cycle until your doctor directs you to stop.

 

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