• Name

  1,2-Epoxybutane

• EINECS 203-438-2
• CAS No. 106-88-7
• Article Data106
• CAS DataBase
• Density 0.88 g/cm³
• Solubility 86.8g/L at 25℃
• Melting Point -130oC
• Formula C₄H₈O
• Boiling Point 63.4 °C at 760 mmHg
• Molecular Weight 72.1069
• Flash Point -15 °C
• Transport Information UN 3022 3/PG 2
• Appearance colourless liquid with an unpleasant smell
• Safety 9-16-29-36/37-61-19
• Risk Codes 11-20/21/22-36/37/38-40-52/53
• Molecular Structure
• Hazard Symbols F, Xn
• Synonyms Butane,1,2-epoxy- (8CI);Oxirane, ethyl- (9CI);1,2-Butene oxide;1,2-Butyleneepoxide;1,2-Butylene oxide;1,2-Epoxybutane;1-Butene oxide;1-Butylene oxide;2-Ethyloxirane;Butene 1,2-epoxide;DL-1,2-Epoxybutane;Ethylethylene oxide;Ethyloxirane;NSC 24240;a-Butylene oxide;
• PSA 12.53000
• LogP 0.79520

Synthetic route

106-98-9

1-butylene

80-15-9

Cumene hydroperoxide

A

106-88-7

ethyloxirane

B

617-94-7

1-methyl-1-phenylethyl alcohol

Conditions

Conditions	Yield
With Ti-HMS at 95℃; under 26252.6 Torr;	A 98.6% B n/a

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106-98-9

1-butylene

106-88-7

ethyloxirane

Conditions

Conditions	Yield
With phosphotungstic acid; phosphoric acid tributyl ester; dihydrogen peroxide In toluene at 70℃; under 3750.38 Torr; for 5h; Temperature; Pressure;	96.8%
With tert.-butylhydroperoxide; 2C13H10N3O2(1-)*MoO2(2+) In methanol; dichloromethane for 1h; Catalytic behavior; Reagent/catalyst;	91%
With dihydrogen peroxide; teterabutylammonium In acetonitrile at 31.85℃; for 8h;	88%

1873-25-2

1-chloro-butan-2-ol

106-88-7

ethyloxirane

Conditions

Conditions	Yield
With Ph4SbOMe In dichloromethane at 40℃; for 3h;	64%
With potassium hydroxide
With Ph4SbOMe In dichloromethane at 40℃; for 4h;	75 % Chromat.

26106-95-6

2-chloro-1-butanol

106-88-7

ethyloxirane

Conditions

Conditions	Yield
With Ph4SbOMe In dichloromethane at 40℃; for 3h;	10%

106-98-9

1-butylene

A

106-88-7

ethyloxirane

B

5077-67-8

1-Hydroxy-2-butanone

Conditions

Conditions	Yield
With oxygen at 500℃; under 5148.6 Torr;

2482-57-7

1-bromo-2-butanol

106-88-7

ethyloxirane

Conditions

Conditions	Yield
With potassium hydroxide

106-98-9

1-butylene

36709-10-1

acetylperoxy radical

106-88-7

ethyloxirane

Conditions

Conditions	Yield
at 83.4 - 137℃; Kinetics; further compounds;

930-22-3

epoxybutene

A

106-88-7

ethyloxirane

B

627-27-0

homoalylic alcohol

C

6117-91-5

(E/Z)-2-buten-1-ol

D

123-72-8

butyraldehyde

E

123-73-9

crotonaldehyde

F

71-36-3

butan-1-ol

Conditions

Conditions	Yield
With hydrogen; at 30℃; under 760 Torr; for 8h; Product distribution; Mechanism; catalytic hydrogenation of the title compound in the presence of various catalysts (cationic rhodium complexes); influence of the type of catalyst's ligand, reaction time and pressure on the activity of catalysts;	A 2.1 % Chromat. B 16.5 % Chromat. C 11.7 % Chromat. D 4.4 % Chromat. E 44.3 % Chromat. F 1.7 % Chromat.
With hydrogen at 80℃; under 16274.9 Torr; Autoclave;

...Expand

24068-63-1

2-bromo-1-butanol

106-88-7

ethyloxirane

Conditions

Conditions	Yield
With potassium carbonate In 1,4-dioxane at 25℃; for 120h; Yield given;

39972-78-6

allyl t-butyl peroxide

106-88-7

ethyloxirane

Conditions

Conditions	Yield
With tert-butyl peroxyacetate at 110℃; under 0.001 Torr; for 12h;

930-22-3

epoxybutene

A

106-88-7

ethyloxirane

B

123-73-9

trans-Crotonaldehyde

C

557-17-5

methyl propyl ether

D

627-40-7

methylallylether

E

123-72-8

butyraldehyde

F

106-97-8

n-butane

Conditions

Conditions	Yield
With hydrogen; silica gel; palladium at -0.15℃; under 150.012 Torr; Product distribution; Mechanism; also ethyloxirane; also with duterium; also over Pt-SiO2; var. temp. and time;

...Expand

106-98-9

1-butylene

oxygen

oxygen

A

106-88-7

ethyloxirane

B

5077-67-8

1-Hydroxy-2-butanone

Conditions

Conditions	Yield
at 340 - 510℃; under 5148.6 Torr;

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106-98-9

1-butylene

atomic oxygen

atomic oxygen

A

106-88-7

ethyloxirane

B

123-72-8

butyraldehyde

C

78-93-3

butanone

...Expand

106-97-8

n-butane

A

106-88-7

ethyloxirane

B

1758-32-3, 1758-33-4, 3266-23-7, 6189-41-9, 21490-63-1, 63864-69-7, 103110-88-9

2,3-epoxybutane

C

75-52-5

nitromethane

D

64-17-5

ethanol

E

78-93-3

butanone

F

78-92-2, 15892-23-6

iso-butanol

G

CO, CO2

CO, CO2

Conditions

Conditions	Yield
With oxygen; dimethyl amine at 291℃; under 123 Torr; Product distribution; study of the oxidation of butane in the presence of primary and secondary amines; variation of pressure and time; mechanism for the formation of nitromethane is proposed;

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106-99-0

buta-1,3-diene

106-88-7

ethyloxirane

Conditions

Conditions	Yield
0.1% gold/titanium/silicon catalyst Product distribution / selectivity;

930-22-3

epoxybutene

A

106-88-7

ethyloxirane

B

627-27-0

homoalylic alcohol

C

6117-91-5

(E/Z)-2-buten-1-ol

D

123-73-9

crotonaldehyde

Conditions

Conditions	Yield
With hydrogen; Ag-Pt/SiO2 Kinetics; Product distribution; Further Variations:; Catalysts; effect of Ag addition;

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106-98-9

1-butylene

592-41-6

1-hexene

A

106-88-7

ethyloxirane

B

1436-34-6

1,2-Epoxyhexane

Conditions

Conditions	Yield
With dihydrogen peroxide In water; acetonitrile at 59.84℃; under 1824.12 Torr; for 12h;	A 72 %Chromat. B 27 %Chromat.

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2404-44-6

1,2-Epoxydecane

872313-01-4

C6H14OS

A

106-88-7

ethyloxirane

B

100392-70-9

2-hydroxybutyl n-octyl sulfide

Conditions

Conditions	Yield
In chlorobenzene Kinetics;

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96-09-3

styrene oxide

872313-01-4

C6H14OS

A

106-88-7

ethyloxirane

B

67210-33-7, 67210-38-2, 136656-75-2, 79345-23-6

(±)-1-(phenylthio)butan-2-ol

Conditions

Conditions	Yield
In chlorobenzene Kinetics;

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1,2-Epoxybutane Toxicity Data With Reference

1,2-Epoxybutane Consensus Reports

1,2-Epoxybutane Safety Profile

1,2-Epoxybutane Standards and Recommendations