1-Methylpyridinium chloride supplier

Name
1-Methylpyridinium chloride
EINECS 231-658-9
CAS No. 7680-73-1
Article Data13
CAS DataBase
Density
Solubility
Melting Point 144 °C
Formula C6H8 N . Cl
Boiling Point
Molecular Weight 129.589
Flash Point
Transport Information
Appearance
Safety Poison by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of Cl⁻ and NO_x.
Risk Codes 20/21/22-36/37/38
Molecular Structure
Hazard Symbols
Synonyms 1-Methylpyridiniumchloride (6CI,7CI); Pyridinium, 1-methyl-, chloride (8CI,9CI); Methylpyridiniumchloride; N-Methylpyridinium chloride
PSA 3.88000
LogP -2.48490

Synthetic route

: 38542-71-1
N-methylpyridinium p-toluenesulfonate

: 7680-73-1
N-methylpyridinium chloride

Conditions

Conditions	Yield
With Dowex 1-X8 (Cl) 100-200 mesh standard grade resin In water Inert atmosphere;	97%

: 110-86-1
pyridine

: 88470-26-2
N,N-dimethoxyamine

: 7680-73-1
N-methylpyridinium chloride

Conditions

Conditions	Yield
With tert-butylhypochlorite In diethyl ether at -78 - -8℃;	21%

: 110-86-1
pyridine

: 74-87-3
methylene chloride

: 7680-73-1
N-methylpyridinium chloride

Conditions

Conditions	Yield
Thermodynamic data; Heating;
In ethanol at 80℃; under 3750.38 Torr; for 6h; Temperature; Pressure;
With benzene

: 628-13-7
pyridine hydrochloride

: 7680-73-1
N-methylpyridinium chloride

Conditions

Conditions	Yield
With methanol at 160℃;
With formaldehyd at 200℃;

: 110-86-1
pyridine

: 17230-31-8
2-methoxy-1,3-dioxane

A: 7680-73-1
N-methylpyridinium chloride

B: 107-18-6
allyl alcohol

Conditions

Conditions	Yield
With di-tert-butyl peroxide In tetrachloromethane at 20℃; Irradiation; posiible mechanism discussed; relative rates of hydrogen abstraction were determined both by EPR technique (Me3COOCMe3) and by GC (this conditions); stereoelectronic effects in this process was compared for a series of 1,3-dioxanes;

...Expand

: N-methyl-3-dehydropyridinium ylid

: 7680-73-1
N-methylpyridinium chloride

Conditions

Conditions	Yield
With hydrogenchloride In methanol at -196.15℃; protonation;	0.19 mmol

: 7647-01-0
hydrogenchloride

: 5-(2,4-dinitro-anilino)-penta-2,4-dienal-methylimine

: 7680-73-1
N-methylpyridinium chloride

: 110-86-1
pyridine

hydrogen chloride: hydrogen chloride

: 7680-73-1
N-methylpyridinium chloride

Conditions

Conditions	Yield
With methanol

: 96-54-8
N-Methylpyrrole

: 7440-44-0
pyrographite

A: 54560-59-7
3-iodo-N-methylpyridinium chloride

B: 7680-73-1
N-methylpyridinium chloride

Conditions

Conditions	Yield
Stage #1: N-Methylpyrrole; pyrographite With methyl iodide at -196.15℃; Iodination; addition; electric arc; Stage #2: With hydrogenchloride In methanol at -196.15℃; acidolysis;

...Expand

: 96-54-8
N-Methylpyrrole

: 7440-44-0
pyrographite

A: 7680-73-1
N-methylpyridinium chloride

B: 3-chloro-N-methylpyridinium chloride

Conditions

Conditions	Yield
Stage #1: N-Methylpyrrole; pyrographite With methylene chloride at -196.15℃; Chlorination; addition; electric arc; Stage #2: With hydrogenchloride In methanol at -196.15℃; acidolysis;

...Expand

: 96-54-8
N-Methylpyrrole

: 7440-44-0
pyrographite

A: 7680-73-1
N-methylpyridinium chloride

B: 3-chloro-N-methylpyridinium chloride

C: 3-fluoro-N-methylpyridinium chloride

Conditions

Conditions	Yield
Stage #1: N-Methylpyrrole; pyrographite With chlorotrifluoromethane at -196.15℃; Fluorination; chlorination; addition; electric arc; Stage #2: With hydrogenchloride In methanol at -196.15℃; acidolysis;

...Expand

: 96-54-8
N-Methylpyrrole

: 124-38-9
carbon dioxide

: 7440-44-0
pyrographite

A: 535-83-1
Trigonelline

B: 7680-73-1
N-methylpyridinium chloride

Conditions

Conditions	Yield
Stage #1: N-Methylpyrrole; carbon dioxide; pyrographite at -196.15℃; Addition; carboxylation; electric arc; Stage #2: With hydrogenchloride In methanol at -196.15℃; acidolysis;

...Expand

: 6138-41-6
trigonelline hydrochloride

A: 110-86-1
pyridine

B: 59-67-6
nicotinic acid

C: 38078-47-6
1,4-dimethylpyridinium chloride

D: 7680-73-1
N-methylpyridinium chloride

Conditions

Conditions	Yield
at 220℃; Product distribution; Further Variations:; Temperatures; time dependence;

...Expand

: 96-54-8
N-Methylpyrrole

<(Os(NH3)5(OTf)>(OTf)2: <(Os(NH3)5(OTf)>(OTf)2

: 7680-73-1
N-methylpyridinium chloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: -196.15 °C / electric arc 2: 0.19 mmol / HCl / methanol / -196.15 °C View Scheme

: 14243-64-2
(triphenylphosphine)gold(I) chloride

: 7680-73-1
N-methylpyridinium chloride

: 158871-27-3
4,5-bis(cyanoethylthio)-1,3-dithiole-2-[(4,5-ethylenedithio)-1,3-dithiole-2-ylidene]

: 782500-50-9
[N-methylpyridinium][Au(triphenylphosphine)(2-((4,5-ethylenedithio)-1,3-dithiole-2-ylidene)-1,3-dithiole-4,5-dithionato)]

Conditions

Conditions	Yield
With Na In ethanol; dichloromethane (Ar); dissolving of C8H4S8(CH2CH2CN)2 in EtOH soln. containing Na; addn.with stirring of soln. of AuCl(PEt3) and N-methylpyridinium chloride in CH2Cl2; stirring for 30 min; pptn., filtration, washing with CH2Cl2 and MeOH, drying in vac., elem. anal.;	70%

...Expand

: 45078-17-9
1,1,2,3,3-pentacyano-propene

: 7680-73-1
N-methylpyridinium chloride

: 108880-12-2
N-methylpyridinium 1,1,2,3,3-pentacyanopropenide

Conditions

Conditions	Yield
salt formation;

: 67-56-1
methanol

: 64-18-6
formic acid

: 590-29-4
potassium formate

: 7680-73-1
N-methylpyridinium chloride

A: 110-86-1
pyridine

B: 626-67-5
N-methylcyclohexylamine

C 1,1-dimethyl-piperidinium chloride: 1,1-dimethyl-piperidinium chloride

Conditions

Conditions	Yield
at 200℃;

...Expand

: 7680-73-1
N-methylpyridinium chloride

: 694-55-3
N-methyl-3,4-didehydropiperidine

Conditions

Conditions	Yield
With sodium tetrahydroborate In ethanol at 0℃;

: 7680-73-1
N-methylpyridinium chloride

: (3R,4R)-1-Methyl-piperidine-3,4-diol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: NaBH4 / ethanol / 0 °C 2: aq. H2O2; HCO2H / 168 h / 30 °C View Scheme

: copper(II) choride dihydrate

: 7680-73-1
N-methylpyridinium chloride

: 1-methylpyridinium aqua-di-μ-chloro-trichlorodicuprate(II)

Conditions

Conditions	Yield
With H2O In hydrogenchloride mixing equimolar quantities of 1-methylpyridinium chloride and copper(II) chloride dihydrate in concd. HCl soln.;;

: 7647-01-0
hydrogenchloride

: 7680-73-1
N-methylpyridinium chloride

: copper dichloride

A: C5H5NCH3(1+)*2Cu(2+)*5Cl(1-)*H2O=(C5H5NCH3)(Cu2Cl5(H2O))

: 1-methylpyridinium decachlorotetracuprate(II)

Conditions

Conditions	Yield
In hydrogenchloride equimolar amts. of Cu-salt and pyridinium salt in concd. HCl; crystn. on slow evapn., recrystn. in presence of excess CuCl2;

...Expand

: 68494-08-6
4,5-bis(benzoylthio)-1,3-dithiole-2-thione

: 7680-73-1
N-methylpyridinium chloride

: copper dichloride

: bis(N-methyl pyridinium) bis(2-thione-1,3-dithiole-4,5-dithiolato)copper(II)

Conditions

Conditions	Yield
With sodium ethoxide In methanol; ethanol under N2; (PhCO)2DMIT deprotected with sodium ethoxide in EtOH; MeOH soln. of CuCl2 added with stirring; MeOH soln. of (MeNC5H5)Cl added;

...Expand

: 7680-73-1
N-methylpyridinium chloride

: 143406-35-3
25,27-dihydroxy-26,28-dipropoxycalix[4]arene

: C6H8N(1+)*C34H36O4*Cl(1-)

Conditions

Conditions	Yield
In chloroform-d1 at 26.84℃; Kinetics; Inert atmosphere;

: 7680-73-1
N-methylpyridinium chloride

: 163311-02-2
25,26-27,28-biscrown-3-calix<4>arene

: C6H8N(1+)*C36H36O6*Cl(1-)

Conditions

Conditions	Yield
In chloroform-d1 at 26.84℃; Kinetics; Inert atmosphere;

: 7680-73-1
N-methylpyridinium chloride

: 323208-38-4
5-(N-phenylureido)methyl-25,26-27,28-bis(crown-3)-calix[4]arene

: C6H8N(1+)*C44H44N2O7*Cl(1-)

Conditions

Conditions	Yield
In chloroform-d1 at 26.84℃; Kinetics; Inert atmosphere;

: 7680-73-1
N-methylpyridinium chloride

: 5-(N-phenylureido)methyl-26,28-dihydroxy-25,27-dipropoxycalix[4]arene

: C6H8N(1+)*C42H44N2O5*Cl(1-)

Conditions

Conditions	Yield
In chloroform-d1 at 26.84℃; Kinetics; Inert atmosphere;

: 7680-73-1
N-methylpyridinium chloride

: 626-67-5
N-methylcyclohexylamine

Conditions

Conditions	Yield
Stage #1: N-methylpyridinium chloride With hydrogen at 130℃; under 45004.5 Torr; for 12h; Stage #2: With sodium hydroxide Temperature; Pressure;

: C35H30O5

: 7680-73-1
N-methylpyridinium chloride

: C6H8N(1+)*Cl(1-)*C35H30O5

Conditions

Conditions	Yield
In d(4)-methanol at 24.84℃; Inert atmosphere;

1-Methylpyridinium chloride Chemical Properties

IUPAC: 1-Methylpyridin-1-ium chloride
Methyl pyridinium chloride (7680-73-1) is also called for 1-Methylpyridinium chloride ; EINECS 231-658-9 ; N-Methylpyridinium chloride ; Pyridine methochloride ; 1-Methylpyridinium chloride ; Pyridinium, 1-methyl-, chloride ; 694-56-4(Parent) ; CID82116 and so on.
Molecular Formula: C₆H₈ClN
Molecular Weight: 129.59
EINECS: 231-658-9
Melting Point: 144°C
LogP: ACD/LogP: -3.59
ACD/LogD (pH 5.5): -3.59
ACD/LogD (pH 7.4): -3.59
ACD/BCF (pH 5.5): 1
ACD/BCF (pH 7.4): 1
ACD/KOC (pH 5.5): 1
ACD/KOC (pH 7.4): 1
H bond acceptors: 1
H bond donors: 0
Freely Rotating Bonds: 0
Topological Polar Surface Area: 3.9
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 46.1
Isotope Atom Count: 0
Defined Atom StereoCenter Count: 0
Undefined Atom StereoCenter Count: 0
Defined Bond StereoCenter Count: 0
Undefined Bond StereoCenter Count: 0
Covalently-Bonded Unit Count: 2
The molecular structure of Methyl pyridinium chloride (7680-73-1):

1-Methylpyridinium chloride Uses

Methyl pyridinium chloride (7680-73-1) is used as chemical product.

1-Methylpyridinium chloride Toxicity Data With Reference

1.	orl-rat LD50:285 mg/kg	GISAAA Gigiena i Sanitariya. 49 (1)(1984),74.
2.	scu-rat LD50:280 mg/kg	APFRAD Annales Pharmaceutiques Francaises. 8 (1950),773.
3.	orl-mus LD50:286 mg/kg	GISAAA Gigiena i Sanitariya. 49 (1)(1984),74.
4.	ipr-mus LDLo:220 mg/kg	JCINAO Journal of Clinical Investigation. 25 (1946),908.

RTECS: UU5950000

1-Methylpyridinium chloride Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of Cl⁻ and NO_x.

Risk Statements: 20/21/22-36/37/38
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed
R36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 36/37/39
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection

Product Name

1-Methylpyridinium chloride

Synthetic route

1-Methylpyridinium chloride Chemical Properties

1-Methylpyridinium chloride Uses

1-Methylpyridinium chloride Toxicity Data With Reference

1-Methylpyridinium chloride Safety Profile

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