15-Crown-5 supplier | CasNO.33100-27-5

Name
15-Crown-5
EINECS 251-379-6
CAS No. 33100-27-5
Article Data27
CAS DataBase
Density 0.995 g/cm³
Solubility MISCIBLE
Melting Point -20oC
Formula C₁₀H₂₀O₅
Boiling Point 350.9 °C at 760 mmHg
Molecular Weight 220.266
Flash Point 139.1 °C
Transport Information
Appearance colourless liquid
Safety 26-39-36
Risk Codes 22-36/38-36-20/22-36/37/38-20/21/22
Molecular Structure
Hazard Symbols Xn,Xi
Synonyms 5-19-12-00252 (Beilstein Handbook Reference);1,4,10,13-Pentaoxacyclopentadecane;15-crown-5 ether;15-Crown-5(1,4,7,10,13-Pentaoxacyclopentadecane);
PSA 46.15000
LogP 0.08300

Synthetic route

: 63689-58-7
1,4,7,10,13-pentaoxacyclopentadecane-2,6-dione

: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 1.5h;	79%

: 4792-15-8
Pentaethylene glycol

: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
With sodium hydroxide; p-toluenesulfonyl chloride In 1,4-dioxane at 80℃;	75%
With sodium hydroxide; p-toluenesulfonyl chloride In 1,2-dimethoxyethane at 0℃; Product distribution; var. solvents, reagents, and temp.; other oligoethylene glycols;	36 % Chromat.

: 112-60-7
Tetraethylene glycol

: 107-21-1
ethylene glycol

: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
With sodium carbonate; dicyclohexyl-carbodiimide In 1,4-dioxane at 70 - 75℃; for 6h; Concentration; Reagent/catalyst; Temperature; Solvent;	70.2%

: 111-44-4
3-oxa-1,5-dichloropentane

: 112-27-6
2,2'-[1,2-ethanediylbis(oxy)]bisethanol

: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
With sodium methylate In 1,4-dioxane for 24h; Heating; metal hydroxides, different bases as 'template' agents;	66%
With sodium methylate In 1,4-dioxane for 24h; Heating;	66%

: 86309-76-4
1,4,7,10,13-Pentaoxacyclopentadecane-2,3-dithione

: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
With nickel In diethyl ether; dichloromethane at 0℃; for 1h;	52%

: 4792-15-8
Pentaethylene glycol

A: 33100-27-5
15-crown-5

B: 71092-63-2
<60>crown-20

C: 52985-64-5
<30>crown-10

D: 109635-67-8
45-Crown-15

Conditions

Conditions	Yield
With potassium hydroxide; p-toluenesulfonyl chloride In 1,4-dioxane at 65℃;	A 46% B 0.7% C 12% D 3.4%

...Expand

: 4792-15-8
Pentaethylene glycol

A: 33100-27-5
15-crown-5

B: 52985-64-5
<30>crown-10

C: 109635-67-8
45-Crown-15

Conditions

Conditions	Yield
With potassium hydroxide; p-toluenesulfonyl chloride In 1,4-dioxane at 65℃;	A 46% B 12% C 3.4%

...Expand

: 112-26-5
1,2-bis(2-chloroethoxy)ethane

: 111-46-6
diethylene glycol

: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
With potassium hydroxide for 0.133333h; microwave irradiation;	40%

: 7460-82-4
diethylene glycol ditosylate

: 112-27-6
2,2'-[1,2-ethanediylbis(oxy)]bisethanol

: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
With aluminum oxide; potassium fluoride In acetonitrile for 24h; Ambient temperature;	25%

: 17455-13-9
18-crown-6 ether

: C14H14Mg*C10H20O5

A: 33100-27-5
15-crown-5

B: C14H14Mg*C12H24O6

Conditions

Conditions	Yield
In benzene at 25℃; Equilibrium constant;

...Expand

: 61060-13-7
complex of 15-crown-5 with K+

: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
In methanol at 25℃; Equilibrium constant;
In acetone at 25℃; Equilibrium constant; complexation of alkali metal cations (Li+, Na+, K+, Rb+, Cs+) with crown ethers, diaza crown ethers and cryptands in acetone, stability constants of complexes formed; influence of ion-pair formation on stability constants;

: 59890-71-0
complex of 15-crown-5 with Na+

: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
In methanol at 25℃; Equilibrium constant;

: 59890-71-0
complex of 15-crown-5 with Na+

A: 33100-27-5
15-crown-5

B: 17341-25-2
sodium cation

Conditions

Conditions	Yield
In methanol; water at 25℃; Equilibrium constant; var. MeOH/H2O ratio;

: C10H20O5*C6H2N3O7(1-)*K(1+)

A: 33100-27-5
15-crown-5

B: 573-83-1
potassium picrate

Conditions

Conditions	Yield
In dichloromethane; water at 25℃; for 0.666667h; Equilibrium constant;

: C10H20O5*C6H2N3O7(1-)*Cs(1+)

A: 33100-27-5
15-crown-5

B: 3638-61-7
cesium picrate

Conditions

Conditions	Yield
In dichloromethane; water at 25℃; for 0.666667h; Equilibrium constant;

: C10H20O5*C6H2N3O7(1-)*Na(1+)

A: 33100-27-5
15-crown-5

B: 3324-58-1
sodium picrate

Conditions

Conditions	Yield
In dichloromethane; water at 25℃; for 0.666667h; Equilibrium constant;

: C10H20O5*C6H2N3O7(1-)*Rb(1+)

A: 33100-27-5
15-crown-5

B: 23296-29-9
rubidium picrate

Conditions

Conditions	Yield
In dichloromethane; water at 25℃; for 0.666667h; Equilibrium constant;

: C10H20O5*C7H7N2(1+)*BF4(1-)

A: 33100-27-5
15-crown-5

B: 95-49-8
2-methylchlorobenzene

Conditions

Conditions	Yield
In 1,2-dichloro-ethane at 20℃; Rate constant; Kinetics; Thermodynamic data; var. crown ethers, ΔH(excit.), ΔS(excit.);

: C10H20O5*C8H9N2(1+)*BF4(1-)

A: 33100-27-5
15-crown-5

B: 89-96-3
1-chloro-2-ethylbenzene

Conditions

Conditions	Yield
In 1,2-dichloro-ethane at 20℃; Rate constant; Kinetics; Thermodynamic data; var. crown ethers, ΔH(excit.), ΔS(excit.);

: o-acetylbenzenediazonium tetrafluoroborate

A: 33100-27-5
15-crown-5

B: 2142-68-9
1-(2-chlorophenyl)ethanone

Conditions

Conditions	Yield
In 1,2-dichloro-ethane at 20℃; Rate constant; Kinetics; Thermodynamic data; var. crown ethers, ΔH(excit.), ΔS(excit.);

: C10H20O5*C3H9N*H(1+)

A: 33100-27-5
15-crown-5

B: 145384-53-8
trimethylammonium

Conditions

Conditions	Yield
Thermodynamic data; enthalpy and entropy changes for the complex dissociation reaction: ΔH0D, ΔS0D;

: C10H20O5*C6H13N*H(1+)

A: 29384-28-9
cyclohexyl-ammonium cation

B: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
Thermodynamic data; enthalpy and entropy changes for the complex dissociation reaction: ΔH0D, ΔS0D;

: C10H20O5*C5H5N*H(1+)

A: 16969-45-2
pyridin-1-ium

B: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
Thermodynamic data; enthalpy and entropy changes for the complex dissociation reaction: ΔH0D, ΔS0D;

: 19249-03-7
triethylene glycol di-(p-toluenesulfonate)

: 111-46-6
diethylene glycol

: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
With aluminum oxide; potassium fluoride In acetonitrile for 24h; Ambient temperature;	33 % Chromat.

: C10H20O5*ClO4(1-)*Li(1+)

: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
In acetone Equilibrium constant; various solvents (MeNO2, MeCN, propylene carbonate, MeOH, pyridine), complex formation between crown ethers and lithim ion, effect of solvent of the stability of complexes, 7Li NMR study;
In acetone Equilibrium constant; various solvents (MeNO2, MeCN, MeOh H2O etc.), complex formation between crown ethers and lithim ion, effect of solvent of the stability of complexes;

: 1,4,7,10,13-Pentaoxa-cyclopentadecane; compound with GENERIC INORGANIC NEUTRAL COMPONENT

: 33100-27-5
15-crown-5

Conditions

Conditions	Yield
With Iodine monochloride In benzene at 24.9℃; Equilibrium constant;

: 61060-13-7
complex of 15-crown-5 with K+

: 31250-06-3
cryptand 211

A: 33100-27-5
15-crown-5

B: C14H28N2O4*K(1+)

Conditions

Conditions	Yield
In gas at 76.9℃; Equilibrium constant; Thermodynamic data; ΔG0;

...Expand

: 59890-71-0
complex of 15-crown-5 with Na+

: 31250-06-3
cryptand 211

A: 33100-27-5
15-crown-5

B: C14H28N2O4*Na(1+)

Conditions

Conditions	Yield
In gas at 76.9℃; Equilibrium constant; Thermodynamic data; ΔG0;

...Expand

: 74060-72-3
C10H20O5*Li(1+)

: 31250-06-3
cryptand 211

A: 33100-27-5
15-crown-5

B: C14H28N2O4*Li(1+)

Conditions

Conditions	Yield
In gas at 76.9℃; Equilibrium constant; Thermodynamic data; ΔG0;

...Expand

: 33100-27-5
15-crown-5

: 851576-85-7
[W(carbonyl)5([bis(trimethylsilyl)methyl]cyanophosphane)]

: 1070-89-9
sodium hexamethyldisilazane

: 947333-62-2
[(OC)5WP(CH(SiMe3)2)CNNa(15-crown-5)]

Conditions

Conditions	Yield
In tetrahydrofuran under Ar; cooled (-80°C) soln. of NaN(SiMe3)2 in THF added dropwise to stirred soln. of W complex in THF and 15-crown-5; warmed slowly toroom temp. for 3.5 h; solvent removed under vac.; washed with Et2O and n-pentane; dried under reduced pressure; elem. anal.;	100%

...Expand

: 33100-27-5
15-crown-5

: Br(1-)*C10H20NaO5

Conditions

Conditions	Yield
With sodium bromide In water at 20℃; for 12h;	100%

: 33100-27-5
15-crown-5

: C10H20NaO5*HO(1-)

Conditions

Conditions	Yield
With sodium hydroxide In water at 20℃; for 12h;	100%

: 33100-27-5
15-crown-5

: C10H20NaO5*IO3(1-)

Conditions

Conditions	Yield
With sodium iodate In water at 20℃; for 12h;	100%

: 33100-27-5
15-crown-5

: 127-09-3
sodium acetate

: C2H3O2(1-)*C10H20NaO5

Conditions

Conditions	Yield
In water at 20℃; for 12h;	100%

: 33100-27-5
15-crown-5

: 62-76-0
sodium oxalate

: C2O4(2-)*2C10H20NaO5

Conditions

Conditions	Yield
In water at 20℃; for 12h;	100%

: 33100-27-5
15-crown-5

: 877-24-7
potassium hydrogen phthalate

: C8H5O4(1-)*C12H24KO6

Conditions

Conditions	Yield
In water at 20℃; for 12h;	100%

: 33100-27-5
15-crown-5

: 7647-14-5
sodium chloride

: 7646-85-7
zinc(II) chloride

: C10H20NaO5(1+)*Cl3Zn(1-)

Conditions

Conditions	Yield
Stage #1: 15-crown-5; sodium chloride In water at 20℃; for 12h; Stage #2: zinc(II) chloride In ethanol for 12h; Reflux;	100%

...Expand

: 33100-27-5
15-crown-5

: iron(III) chloride hexahydrate

: 7647-14-5
sodium chloride

: Cl4Fe(1-)*C10H20NaO5(1+)

Conditions

Conditions	Yield
Stage #1: 15-crown-5; sodium chloride In water at 20℃; for 12h; Stage #2: iron(III) chloride hexahydrate In ethanol for 12h; Reflux;	100%

...Expand

: 7647-01-0
hydrogenchloride

: 33100-27-5
15-crown-5

: uranyl acetate dihydrate

: 127-09-3
sodium acetate

: 2Na(1+)*2(CH2)10O5*UO2Cl4(2-)=[Na(CH2)10O5]2UO2Cl4

Conditions

Conditions	Yield
In water UO2OAc2*2H2O, NaCH3COO, ligand and HCl were combined in water with stirring, evapd. slowly at room temp. for 1 wks; isolated; elem. anal.;	99.9%

...Expand

: 33100-27-5
15-crown-5

: 1242245-34-6
[NaU(bis(trimethylsilyl)amide)(CH2SiMe2N(SiMe3))2]

: [Na(15-crown-5)][U(bis(trimethylsilyl)amide)(CH2SiMe2N(SiMe3))2]

Conditions

Conditions	Yield
In pentane under Ar; a NMR tube was charged with U-contg. compd. (0.027 mmol) in pentane, and 15-crown-5 (0.032 mmol) was added; the suspn. was heated for 3 d at 60°C; elem. anal.;	99%

: 33100-27-5
15-crown-5

: 1450-18-6
1,1,1-trimethyl-2,2,2-triphenyldisilane

: [Na(15-crown-5)SiPh3]·(thf )0.5

Conditions

Conditions	Yield
With sodium t-butanolate In tetrahydrofuran at 20℃; for 2h; Inert atmosphere; Schlenk technique;	99%

sodium amalgam: sodium amalgam

: 33100-27-5
15-crown-5

: C60H51B3N12(1-)

: C60H51B3N12(1-)*C10H20NaO5(1+)

Conditions

Conditions	Yield
In tetrahydrofuran; hexane	99%

...Expand

: 33100-27-5
15-crown-5

: 10026-11-6
zirconium(IV) chloride

: sodium fluoride

: {Na-15-crown-5}2-cis-{ZrF2Cl4}

Conditions

Conditions	Yield
In acetonitrile soln. of ZrCl4 and 15-crown-5 prepared under cooling; addn. of NaF; stirred for 12 h at 25°C; filtration; solvent removed until beginning of crystn.; cooled down to 5°C; crystn.; filtration; washed (cold acetonitrile); dried under vac.; elem. anal.; IR;	98.3%

...Expand

: 33100-27-5
15-crown-5

: niobium pentachloride

: (NbCl4)2(15-crown-5)

Conditions

Conditions	Yield
In tetrachloromethane Ar-atmosphere; room temp.; elem. anal.;	98%

: 33100-27-5
15-crown-5

: 1331740-29-4
Na[U(N(SiMe3)2)(OC(=CH2)SiMe2NSiMe3)2(N3)]

: 109-66-0
pentane

: Na(C10H20O5)[U(N3)(NSi2C6H18)(COCH2Si(CH3)2N(Si(CH3)3))2]*0.5C5H12

Conditions

Conditions	Yield
In pentane Ar; U compd. and ligand (1:1 molar ratio), stirred for 12 at 20°C; filtered, evapd., elem. anal.;	98%

...Expand

: 14760-22-6
iron(II) bis(trimethylsilyl)amide

: 33100-27-5
15-crown-5

: 1070-89-9
sodium hexamethyldisilazane

: [Na(15-crown-5)2]+[Fe(N{SiMe3}2)3]−

Conditions

Conditions	Yield
Stage #1: iron(II) bis(trimethylsilyl)amide; sodium hexamethyldisilazane In toluene for 1h; Reflux; Inert atmosphere; Glovebox; Schlenk technique; Stage #2: 15-crown-5 In toluene for 1h; Reflux; Inert atmosphere; Glovebox; Schlenk technique;	97.74%

...Expand

: 33100-27-5
15-crown-5

: dihydroxy-anthraquinone-C60

: bis(sodium-15-crown-5)dioxoanthraquinone-C60

Conditions

Conditions	Yield
With sodium t-butanolate In tetrahydrofuran; toluene Ambient temperature;	97%

: ammonium dichromate(VI)

: 33100-27-5
15-crown-5

: NH4CrO3Cl(15-crown-5)2

Conditions

Conditions	Yield
With hydrogenchloride In water addn. of org. ligand to soln. of ammonium dichromate and concd. hydrochloric acid (stirring, 20°C); ppt. filtered off, washed (water) and dried at 40-50°C; elem. anal.;	97%

: 33100-27-5
15-crown-5

: Ni(1,3-imidazolidinyl-N,N'-bis(benzene-2-thiolate)2) * DMF

: 930-69-8
sodium thiophenolate

: [Na(1,4,7,10,13-pentaoxacyclopentadecane)][Ni(SPh)(1,3-imidazolidinyl-N,N'-bis(benzene-2-thiolate))]

Conditions

Conditions	Yield
In tetrahydrofuran N2-atmosphere; mixing Ni-complex with excess NaSPh, addn. of MeOH, stirring for 1 d, filtration, addn. of excess of crown; crystn. (-30°C, 3 d), collection (filtration), washing (THF, hexane), drying (vac., 2 h); elem. anal.;	97%

...Expand

: 2,6-dimesitylphenyl-trifluorosilane

: 33100-27-5
15-crown-5

: 1195787-45-1
C10H20O5*C24H25F4Si(1-)*Na(1+)

Conditions

Conditions	Yield
With sodium fluoride In toluene for 648h; Inert atmosphere;	97%

: tin(II) trifluoromethanesulfonate

: 33100-27-5
15-crown-5

: [tin(II)([15]crown-5)2](trifluoromethanesulfonate)2

Conditions

Conditions	Yield
In tetrahydrofuran standard inert-atmosphere techniques; soln. of (15)crown-5 (0.972 mmol) added to soln. of Sn(OTf)2 (0.480 mmol), stiired for 2 h; solvent removed (in vac.), washed with pentane; elem. anal.;	97%

: 33100-27-5
15-crown-5

: magnesium bis(tetrahydroborate) tris(tetrahydrofuran)

: magnesium bis(tetrahydroborate) bis(15-crown-5)

Conditions

Conditions	Yield
In tetrahydrofuran	96.1%
In tetrahydrofuran byproducts: THF; under N2 15-crown-5 was added dropwise to THF soln. of Mg-compd.; ppt. was centrifuged off, dried in vac., elem. anal.;	96.1%

: 33100-27-5
15-crown-5

: 113236-05-8
MoF4(NCl)

: sodium fluoride

: sodium-15-crown-5-pentafluoro-N-chloronitreno-molybdate(IV)

Conditions

Conditions	Yield
In acetonitrile stirring (room temp., 2 h); crystn. on cooling (-18°C), sepn. (filtration off), washing (acetonitrile), drying (vac.); elem. anal.;	96%

...Expand

: 33100-27-5
15-crown-5

: niobium pentachloride

: (NbCl4)3(15-crown-5)

Conditions

Conditions	Yield
In tetrachloromethane Ar-atmosphere; molar ratio Nb2Cl10:crown=1:2, room temp.; elem. anal.;	96%

: 131481-05-5
2-(3-methoxymethoxyphenyl)butane-1,2-diol

: 33100-27-5
15-crown-5

: 74-88-4
methyl iodide

: 131480-48-3
2-methoxy-2-(3-methoxymethoxyphenyl)but-1-yl methyl ether

Conditions

Conditions	Yield
In N-methyl-acetamide; mineral oil	95%

...Expand

: 33100-27-5
15-crown-5

: 2Mo(6+)*2(N3S2)(3-)*6Cl(1-)={MoCl3(N3S2)}2

: sodium fluoride

: {Na-15-crown-5}{MoF2Cl2(N3S2)}

Conditions

Conditions	Yield
In acetonitrile byproducts: NaCl; addn. of NaF to suspn. of Mo-complex, addn. of 15-crown-5 (dropwise), stirring (12 h), sepn. of ppt. (filtration); crystn. on cooling (-20°C), sepn. (filtration off), washing (acetonitrile), drying (vac.); elem. anal.;	95%

...Expand

: 33100-27-5
15-crown-5

: {ReCl3(NO)2}2

: sodium fluoride

: 75-05-8
acetonitrile

: {Na(15-crown-5)}{ReFCl3(NO)(CH3CN)}

Conditions

Conditions	Yield
In acetonitrile heating of 1.8mmol (ReCl3(NO)2)2 in 30ml acetonitrile (formation of sol. (ReCl3(NO)2(CH3CN)), addn. of 3.6mmol NaF amd 0.715ml 15 crown-5; 2h refluxing;; cooling down and concg. of soln.; single crystal;filtn., concgn. of filtrate (20ml); elem. anal.;;	95%

...Expand

: 7446-70-0
aluminium trichloride

: 33100-27-5
15-crown-5

: 111523-29-6
{AlCl2((CH2CH2O)5)}(1+)*AlCl4(1-)={AlCl2((CH2CH2O)5)}{AlCl4}

Conditions

Conditions	Yield
In tetrahydrofuran all manipulations under dry N2; slowly dissolving AlCl3 in THF, adding 15-crown-5 with stirring, color change from light green to dark green, crystn. (after 30 min); sepg. crystals from the mother soln., drying (vac., 25°C); elem. anal.;	95%

: 33100-27-5
15-crown-5

: scandium chloride * 3 acetonitrile

: 147631-11-6
(ScCl2(C10H20O5))(1+)*Cl(1-)=(ScCl2(C10H20O5))Cl

Conditions

Conditions	Yield
In acetonitrile Sc-compd. was dissolved in MeCN (under dry inert gas), addn. of crown ether; sepn. of precipitate, washing with MeCN, vac. drying at 30°C, elem. anal.;	95%

15-Crown-5 Chemical Properties

IUPAC Name: 3,6,9,12,15-Pentaoxacyclopentadecane
Molecular Formula: C₁₀H₂₀O₅
Molecular Weight: 220.26 g/mol
Canonical SMILES: C1COCCOCCOCCOCCO1
InChI: InChI=1/C10H20O5/c1-2-12-5-6-14-9-10-15-8-7-13-4-3-11-1/h1-10H2
EINECS: 251-379-6
Classification Code: Drug / Therapeutic Agent; Skin / Eye Irritant
Product Categories: Crown Ethers; Functional Materials; Macrocycles for Host-Guest Chemistry
Stability: Stable. Incompatible with oxidizing agents, strong acids. Avoid exposure to water or moist air.
Water Solubility: Miscible
Sensitive: Hygroscopic
XLogP3: -0.5
H-Bond Acceptor: 5
Index of Refraction: 1.404
Molar Refractivity: 54.14 cm³
Molar Volume: 221.3 cm³
Polarizability: 21.46×10^-24 cm³
Surface Tension: 31.2 dyne/cm
Density: 0.995 g/cm³
Flash Point: 139.1 °C
Enthalpy of Vaporization: 57.2 kJ/mol
Boiling Point: 350.9 °C at 760 mmHg
Water Solubility: 8.82E+04 mg/L at 25 °C
Henry's Law Constant: 2.22E-11 atm-m³/mole at 25 °C
Atmospheric OH Rate Constant: 7.01E-11 cm³/molecule-sec at 25 °C
Vapour Pressure of 15-Crown-5 (CAS NO.33100-27-5): 1.44E-03 mm Hg at 25 °C

15-Crown-5 Uses

15-Crown-5 (CAS NO.33100-27-5) is used as phase transfer catalyst, metal complexing agent, selective removal and separation of cation.

15-Crown-5 Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	514mg/kg (514mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985.
mouse	LD50	oral	1020mg/kg (1020mg/kg)	BEHAVIORAL: TREMOR	Toxicology and Applied Pharmacology. Vol. 44, Pg. 263, 1978.
rabbit	LD50	intraperitoneal	560mg/kg (560mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(2), Pg. 48, 1987.
rabbit	LD50	skin	2520mg/kg (2520mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985.
rat	LD50	intraperitoneal	530mg/kg (530mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985.
rat	LD50	oral	1410mg/kg (1410mg/kg)	BEHAVIORAL: TREMOR	Drug and Chemical Toxicology. Vol. 1, Pg. 339, 1978.

15-Crown-5 Consensus Reports

Reported in EPA TSCA Inventory.

15-Crown-5 Safety Profile

Moderately toxic by ingestion, skin contact, and intraperitoneal routes. A skin and eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes: Harmful Xn, Xi
Risk Statements: 22-36/38-36-20/22-36/37/38-20/21/22
R22: Harmful if swallowed.
R36/38: Irritating to eyes and skin.
R36: Irritating to eyes.
R20/22: Harmful by inhalation and if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-39-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39: Wear eye / face protection.
S36: Wear suitable protective clothing.
RIDADR: 2810
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 6.1(b)
PackingGroup of 15-Crown-5 (CAS NO.33100-27-5): III

15-Crown-5 Specification

15-Crown-5 (CAS NO.33100-27-5), its Synonyms are 1,4,7,10,13-Pentaoxacyclopentadecane ; 15-Crown-5,1,4,7,10,13-Pentaoxa-cyclo-pentadecane ; Crownethers ; Ethyleneoxidecyclicpentamer ; Lead ionophore V . It is colourless liquid. It is a cyclic pentamer of ethylene oxide that has been shown to complex with various cations, including sodium (Na⁺) and potassium (K⁺), but selective binding to lead (Pb²⁺).

Product Name

15-Crown-5

Synthetic route

15-Crown-5 Chemical Properties

15-Crown-5 Uses

15-Crown-5 Toxicity Data With Reference

15-Crown-5 Consensus Reports

15-Crown-5 Safety Profile

15-Crown-5 Specification

Related Products

Hot Products