2,3-Dihydroxybenzoic Acid supplier

Name
2,3-Dihydroxybenzoic acid
EINECS 206-139-5
CAS No. 303-38-8
Article Data65
CAS DataBase
Density 1.559 g/cm³
Solubility Soluble in water, methanol and dimethyl sulfoxide.
Melting Point 204-206 °C(lit.)
Formula C₇H₆O₄
Boiling Point 362.5 °C at 760 mmHg
Molecular Weight 154.122
Flash Point 187.2 °C
Transport Information
Appearance pale brownish to red brownish crystalline powder
Safety 26-36-37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms o-Pyrocatechuicacid (6CI,8CI);1,2-Dihydroxybenzene-3-carboxylic acid;3-Hydroxysalicylic acid;DHBA;NSC 27435;Pyrocatechuic acid;
PSA 77.76000
LogP 0.79600

Synthetic route

: 24677-78-9
2,3-dihydroxybenzaldehyde

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With dihydrogen peroxide In water; acetonitrile at 45℃; for 12h; chemoselective reaction;	82%

: 3943-73-5
2,3-dihydroxybenzoicacid ethylester

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With lithium hydroxide In ethanol; water at 25℃; for 2h;	71%

: 65-85-0
benzoic acid

A: 303-38-8
2,3-Dihydroxybenzoic acid

B: 490-79-9
2,5-dihydroxybenzoic acid.

C: 99-06-9
3-Carboxyphenol

D: 69-72-7
salicylic acid

E: 99-96-7
4-hydroxy-benzoic acid

Conditions

Conditions	Yield
With oxygen; iron(II) sulfate In water at 40℃; for 3h; Product distribution; pH 6.8 buffer;	A 9% B 5% C 14% D 4% E 9%

...Expand

: 65-85-0
benzoic acid

A: 303-38-8
2,3-Dihydroxybenzoic acid

B: 490-79-9
2,5-dihydroxybenzoic acid.

C: 99-06-9
3-Carboxyphenol

D: 99-96-7
4-hydroxy-benzoic acid

Conditions

Conditions	Yield
With oxygen; iron(II) sulfate In water at 40℃; for 3h; Further byproducts given;	A 9% B 5% C 14% D 9%

...Expand

: 610-04-8
3-formylsalicylic acid

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With sodium hydroxide; dihydrogen peroxide

: 520-79-6
2-hydroxy-3-iodobenzoic acid

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With potassium carbonate beim Schmelzen;

: 877-22-5
3-methoxysalicylic acid

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With aluminium trichloride; chlorobenzene
With hydrogenchloride at 140℃; im Rohr;
With aluminium trichloride at 150℃;
With hydrogen bromide at 110 - 120℃;

: 1521-38-6
2,3-dimethoxybenzoic acid

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With hydrogen iodide at 100℃;
Multi-step reaction with 5 steps 1: N,N-dimethyl-formamide; thionyl chloride / dichloromethane / 2 h / 30 - 35 °C 2: ammonium hydroxide / dichloromethane; water / 0.5 h / -5 - 35 °C 3: trichlorophosphate / toluene / 30 - 85 °C 4: triethylamine; aluminum (III) chloride / toluene / 9.5 h / 30 - 75 °C 5: water; hydrogenchloride / toluene / 0.5 h / 15 - 35 °C View Scheme

: 62672-58-6
2-iodo-3-hydroxybenzaldehyde

: furan-2,3,5(4H)-trione pyridine (1:1)

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
at 100℃;

: 23806-63-5
3-(benzyloxy)-2-hydroxybenzoic acid

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With hydrogen bromide at 100 - 110℃;

: 120-80-9
benzene-1,2-diol

A: 99-50-3
3,4-Dihydroxybenzoic acid

B: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With ammonium carbonate; water at 130 - 140℃; im geschlossenen Rohr;

: 120-80-9
benzene-1,2-diol

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With potassium dicarbonate; glycerol at 180 - 210℃;
With potassium dicarbonate
With 2,6-dihydroxybenzoic acid decarboxylase from Rhizobium species; potassium hydrogencarbonate at 30℃; for 24h; pH=8.5; aq. phosphate buffer; Enzymatic reaction; regioselective reaction;

: 148-53-8
3-methoxy-2-hydroxybenzaldehyde

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
ueber mehrere Stufen;
With potassium hydroxide at 250℃;

: 124-38-9
carbon dioxide

: 2539-21-1
o-methoxyphenyl i-propyl ether

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
Multistep reaction;

: 117308-63-1
Anguibactin

A: 51-45-6
histamine

B: 303-38-8
2,3-Dihydroxybenzoic acid

C: 98135-21-8
Dehydrocystine

Conditions

Conditions	Yield
With hydrogenchloride at 100℃; for 24h;

...Expand

: 69-72-7
salicylic acid

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With dihydrogen peroxide; methylene blue In ethanol at 25℃; Quantum yield; Irradiation;
With dihydrogen peroxide; methylene blue In ethanol at 25℃; Irradiation;
Multi-step reaction with 2 steps 1: alcohol; iodine 2: potash / beim Schmelzen View Scheme

: 69-72-7
salicylic acid

A: 303-38-8
2,3-Dihydroxybenzoic acid

B: 490-79-9
2,5-dihydroxybenzoic acid.

Conditions

Conditions	Yield
With iron(III)-acetylacetonate; dihydrogen peroxide; methylene blue at 25℃; for 4h; Product distribution; Mechanism; Irradiation; other salicylic derivatives, hydroxylation;
With oxygen; potassium oxalate; iron(III) chloride In water at 25℃; Product distribution; Irradiation; role of hydrogen peroxide in dyoxygen induced hydroxylation of title compound; photochemicall and thermal (pH 7.1) hydroxylation;
With dihydrogen peroxide In water at 20℃; for 0.5h; Mechanism; Product distribution; Quantum yield; Irradiation; various pH value and reaction time, HClO4 or K2CO3 presence;

: methylene blue

: 69-72-7
salicylic acid

A: 303-38-8
2,3-Dihydroxybenzoic acid

B: 490-79-9
2,5-dihydroxybenzoic acid.

Conditions

Conditions	Yield
With Fe(III)(sal)3(3-); dihydrogen peroxide In water at 25℃; for 1h; Product distribution; Thermodynamic data; Irradiation; other times; presence of O2;

...Expand

: 106296-52-0
2,2-dimethylbenzo[d][1,3]dioxole-4-carboxylic acid

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With sulfuric acid

: 99-06-9
3-Carboxyphenol

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With dihydrogen peroxide In acetonitrile Irradiation;

: 3-(β-D-glucopyranosyloxy)-2-hydroxybenzoic acid

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With β-glucosidase for 168h; Ambient temperature; enzymatic hydrolysis;

: 63-36-5, 38504-14-2, 45749-46-0
salicylate

A: 303-38-8
2,3-Dihydroxybenzoic acid

B: 490-79-9
2,5-dihydroxybenzoic acid.

Conditions

Conditions	Yield
With dihydrogen peroxide; potassium carbonate In water at 20℃; for 0.5h; Mechanism; Product distribution; Quantum yield; Irradiation; various pH value and reaction time;

: 69-72-7
salicylic acid

A: 89-86-1
4-hydroxysalicylic acid

B: 303-38-8
2,3-Dihydroxybenzoic acid

C: 490-79-9
2,5-dihydroxybenzoic acid.

D: 303-07-1
2,6-Dihydroxybenzoic acid

Conditions

Conditions	Yield
With dihydrogen peroxide; iron(II) sulfate In water at 37℃; for 0.0833333h; hydroxylation; Further byproducts given. Title compound not separated from byproducts;

...Expand

: 69-72-7
salicylic acid

A: 64-18-6
formic acid

B: 617-48-1
malic acid

C: 303-38-8
2,3-Dihydroxybenzoic acid

D: 144-62-7
oxalic acid

Conditions

Conditions	Yield
With dihydrogen peroxide at 23℃; for 4h; pH=6.2; Oxidation; UV-irradiation; Further byproducts given;

...Expand

: 69-72-7
salicylic acid

A: 1119-72-8
cis,cis-Muconic acid

B: 141-82-2
malonic acid

C: 303-38-8
2,3-Dihydroxybenzoic acid

D: 123-31-9
hydroquinone

Conditions

Conditions	Yield
With dihydrogen peroxide at 23℃; for 2.5h; pH=6.2; Kinetics; Oxidation; UV-irradiation;

...Expand

: 7664-93-9
sulfuric acid

: 99974-86-4
3-(2,5-dimethoxy-tetrahydro-[2]furyl)-3-oxo-propionic acid methyl ester

A: 2411-83-8
methyl-2,3-dihydroxybenzoate

B: 303-38-8
2,3-Dihydroxybenzoic acid

...Expand

: 124-38-9
carbon dioxide

: 120-80-9
benzene-1,2-diol

Na2CO3: Na2CO3

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
at 160℃;

...Expand

: 120-80-9
benzene-1,2-diol

: 56-81-5
glycerol

potassium dicarbonate: potassium dicarbonate

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
at 180 - 210℃;
at 180℃;

...Expand

: 148-53-8
3-methoxy-2-hydroxybenzaldehyde

potassium hydroxide: potassium hydroxide

: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
at 250℃;

: 7732-18-5
water

: 120-80-9
benzene-1,2-diol

ammonium carbonate: ammonium carbonate

A: 99-50-3
3,4-Dihydroxybenzoic acid

B: 303-38-8
2,3-Dihydroxybenzoic acid

Conditions

Conditions	Yield
at 140℃;

...Expand

: 64-17-5
ethanol

: 303-38-8
2,3-Dihydroxybenzoic acid

: 3943-73-5
2,3-dihydroxybenzoicacid ethylester

Conditions

Conditions	Yield
sulfuric acid for 24h; Reflux;	100%
With sulfuric acid
With sulfuric acid

: 303-38-8
2,3-Dihydroxybenzoic acid

: 98-59-9
p-toluenesulfonyl chloride

: 866528-82-7
2-hydroxy-3-(toluene-4-sulfonyloxy)-benzoic acid

Conditions

Conditions	Yield
With sodium hydroxide In water; acetone at 40℃;	100%

: 67-56-1
methanol

: 303-38-8
2,3-Dihydroxybenzoic acid

: 2411-83-8
methyl-2,3-dihydroxybenzoate

Conditions

Conditions	Yield
With sulfuric acid for 6h; Reflux;	100%
With sulfuric acid at 0℃; for 12h; Heating / reflux;	99%
With thionyl chloride at 20℃;	99%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 72517-15-8
2,3-dihydroxy-5-bromobenzoic acid

Conditions

Conditions	Yield
With bromine; acetic acid at 20℃; for 24h;	99%
With bromine In acetic acid at 20℃; for 16h; Inert atmosphere; regioselective reaction;	99%
With bromine In acetic acid at 20℃;	88%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 75-36-5
acetyl chloride

: 2411-83-8
methyl-2,3-dihydroxybenzoate

Conditions

Conditions	Yield
With sodium hydrogencarbonate In hydrogenchloride; methanol	99%
With sodium hydrogencarbonate In hydrogenchloride; methanol	99%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 108-24-7
acetic anhydride

: 486-79-3
2,3-diacetoxybenzoic acid

Conditions

Conditions	Yield
sulfuric acid In diethyl ether for 12h;	98%
With sulfuric acid In diethyl ether at 20℃; for 12h; Esterification;	91%
With sulfuric acid for 0.416667h; Heating;	74%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 100-39-0
benzyl bromide

: 95922-26-2
benzyl 2,3-bis(benzyloxy)benzoate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide for 5h; Ambient temperature;	98%
With potassium carbonate In acetone for 24h; Inert atmosphere; Reflux;	94%
With potassium carbonate In acetone for 24h; Reflux; Inert atmosphere;	81%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 2411-83-8
methyl-2,3-dihydroxybenzoate

Conditions

Conditions	Yield
With sulfuric acid In methanol	98%
With sulfuric acid In methanol
With sulfuric acid In methanol; water
Multi-step reaction with 2 steps 1: thionyl chloride / 78 °C / Inert atmosphere 2: triethylamine / 16 h / 0 - 25 °C / Inert atmosphere View Scheme
Multi-step reaction with 2 steps 1: thionyl chloride / Reflux 2: triethylamine / chloroform / 18 h / Reflux View Scheme

: 303-38-8
2,3-Dihydroxybenzoic acid

: 70656-95-0
chlorure de 2,3-dioxosulfinylbenzoyle

Conditions

Conditions	Yield
With thionyl chloride; urea at 40℃; for 3h; Cyclization;	97%
With thionyl chloride; urea at 40℃; for 2h; Yield given;
With thionyl chloride for 8h; Heating;

: 67-56-1
methanol

: 303-38-8
2,3-Dihydroxybenzoic acid

: methyl 2,3-dihydroxymethylbenzoate

Conditions

Conditions	Yield
With sulfuric acid for 18h; Reflux;	97%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 100-44-7
benzyl chloride

: 95922-26-2
benzyl 2,3-bis(benzyloxy)benzoate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide Reflux; Inert atmosphere;	96%
With potassium carbonate In N,N-dimethyl-formamide at 90℃;	91%

: 1‐(1,3,4,5‐tetrahydro‐2H‐pyrido[4,3‐b]indol‐2‐yl)ethan‐1‐one

: 303-38-8
2,3-Dihydroxybenzoic acid

: (6a,11b)‐13‐acetyl‐3,4‐dihydroxy‐5H,7H‐6a,11b‐(ethanoiminomethano)isochromeno[3,4‐b]indol‐5‐one

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; methanesulfonic acid; iron(II) phthalocyanine; acetic acid In water; acetonitrile at 5℃; for 0.0833333h;	96%

: 1‐(1,3,4,5‐tetrahydro‐2H‐pyrido[4,3‐b]indol‐2‐yl)ethan‐1‐one

: 303-38-8
2,3-Dihydroxybenzoic acid

: C20H18N2O5

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; methanesulfonic acid; iron(II) phthalocyanine; acetic acid In water; acetonitrile at 5℃; for 0.0833333h;	96%

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 303-38-8
2,3-Dihydroxybenzoic acid

: 86748-78-9
succinimido 2,3-dihydroxybenzoate.

Conditions

Conditions	Yield
With dicyclohexyl-carbodiimide In 1,4-dioxane for 16h;	95%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 100-39-0
benzyl bromide

: 74272-78-9
2,3-dibenzyloxybenzoic acid

Conditions

Conditions	Yield
Stage #1: 2,3-Dihydroxybenzoic acid With sulfuric acid In methanol Stage #2: benzyl bromide With potassium carbonate In methanol; chloroform Stage #3: With barium(II) hydroxide In tetrahydrofuran; water at 50℃;	95%
Stage #1: 2,3-Dihydroxybenzoic acid; benzyl bromide With potassium carbonate In acetone for 24h; Reflux; Stage #2: With lithium hydroxide In methanol; water for 3h; Reflux; Stage #3: With hydrogenchloride In methanol; water at 0℃;	91%
With potassium hydroxide In dimethyl sulfoxide for 4h;	89%

: 110-91-8
morpholine

: 303-38-8
2,3-Dihydroxybenzoic acid

: 592-87-0
lead(II) thiocyanate

: 1257411-46-3
8-hydroxy-2-morpholin-4-yl-4H-1,3-benzoxazin-4-one

Conditions

Conditions	Yield
Stage #1: 2,3-Dihydroxybenzoic acid; lead(II) thiocyanate With dibromotriphenylphosphorane In tetrahydrofuran; dichloromethane at 0 - 20℃; for 4h; Inert atmosphere; Reflux; Stage #2: morpholine In 1,4-dioxane for 4h; Reflux;	95%

...Expand

: 303-38-8
2,3-Dihydroxybenzoic acid

: 75-26-3
isopropyl bromide

: 85686-13-1
2,3-diisopropyloxybenzoic acid

Conditions

Conditions	Yield
Stage #1: 2,3-Dihydroxybenzoic acid; isopropyl bromide With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 50℃; Stage #2: With barium(II) hydroxide In tetrahydrofuran; water at 50℃;	95%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 93-97-0
benzoic acid anhydride

: 102184-11-2
2,3-Dibenzyloxybenzoic acid

Conditions

Conditions	Yield
With pyridine In dichloromethane at 20℃; for 16h;	93%

: 5217-47-0
N,N'-diethyl-2-thiobarbituric acid

: 303-38-8
2,3-Dihydroxybenzoic acid

: C30H28N4O12S2

Conditions

Conditions	Yield
With sodium acetate; potassium hexacyanoferrate(III) In water at 20℃; for 0.166667h;	92%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 824-94-2
p-methoxybenzyl chloride

: 1154500-34-1
4-methoxybenzyl 2,3-bis((4-methoxybenzyl)oxy)benzoate

Conditions

Conditions	Yield
With potassium carbonate; potassium iodide In acetone for 72h; Inert atmosphere; Reflux;	92%
Stage #1: 2,3-Dihydroxybenzoic acid With tetra-(n-butyl)ammonium iodide; potassium carbonate In acetone at 25℃; for 1h; Stage #2: p-methoxybenzyl chloride In acetone Reflux;	70%
With potassium carbonate; sodium iodide In N,N-dimethyl-formamide at 70℃; for 2h;	52%
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 2h; Inert atmosphere;	52%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 8‐fluoro‐2‐tosyl‐2,3,4,5‐tetrahydro‐1H‐pyrido[4,3‐b]indole

: (6a)‐10‐fluoro‐3,4‐dihydroxy‐13‐tosyl‐5H,7H‐6a,11b‐(ethanoiminomethano)isochromeno[3,4‐b]indol‐5‐one

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; methanesulfonic acid; iron(II) phthalocyanine; acetic acid In water; acetonitrile at 5℃; for 0.5h;	91%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 8‐chloro‐2‐(phenylsulfonyl)‐2,3,4,5‐tetrahydro‐1H‐pyrido[4,3‐b]indole

: (6a,11b)‐10‐chloro‐3,4‐dihydroxy‐13‐(phenylsulfonyl)‐5H,7H‐6a,11b‐(ethanoiminomethano)isochromeno[3,4‐b]indol‐5‐one

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; methanesulfonic acid; iron(II) phthalocyanine; acetic acid In water; acetonitrile at 5℃; for 0.166667h;	91%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 8‐chloro‐2‐(phenylsulfonyl)‐2,3,4,5‐tetrahydro‐1H‐pyrido[4,3‐b]indole

: C24H19ClN2O6S

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; methanesulfonic acid; iron(II) phthalocyanine; acetic acid In water; acetonitrile at 5℃; for 0.166667h;	91%

: 1076-38-6
4-hydroxy[1]benzopyran-2-one

: 303-38-8
2,3-Dihydroxybenzoic acid

: 3,4-dihydroxy-6-oxo-6H-benzofuro[3,2-c][1]benzopyron-5-carboxylic acid

Conditions

Conditions	Yield
With sodium acetate; potassium hexacyanoferrate(III) In water for 1h; Michael addition reaction;	90%

: 57260-73-8
N-BOC-1,2-diaminoethane

: 303-38-8
2,3-Dihydroxybenzoic acid

: 197636-95-6
N-(N'-tert-butyloxycarbonylethanediamino)-2,3-bis(benzyloxy)benzamide

Conditions

Conditions	Yield
Stage #1: 2,3-Dihydroxybenzoic acid With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 25℃; for 0.25h; Stage #2: N-BOC-1,2-diaminoethane In N,N-dimethyl-formamide at 25℃; for 0.5h;	90%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 4-(1,3-benzothiazol-2-yl)benzohydrazide

: 3-(5-(4-(benzo[d]thiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diol

Conditions

Conditions	Yield
With trichlorophosphate at 120℃;	89.3%

: 2170-05-0
pentaphenylantimony

: 303-38-8
2,3-Dihydroxybenzoic acid

: [Ph4Sb]+[Ph4Sb(O2C6H3CO2H)]−

Conditions

Conditions	Yield
In toluene for 1h; Sealed tube; Heating;	89%

: tetramethylammonium hydroxide pentahydrate

: tungsten(VI) oxide monohydrate

: 303-38-8
2,3-Dihydroxybenzoic acid

: endo,endo-(NMe4)2[WO2(2,3-dihydroxybenzoic acid(2-))2]*2H2O

Conditions

Conditions	Yield
In water tungstic acid, 2,3-dihydroxybenzoic acid, Me4NOH refluxed overnight in H2O; hot filtered; evapd. to dryness; washed with hot THF, CH2Cl2, Et2O; vac.dried at 70°C;	87%

...Expand

: 303-38-8
2,3-Dihydroxybenzoic acid

: 54-11-5
nicotin

: nicotine 2,3-dihydroxybenzoate

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 1h;	86%

: 303-38-8
2,3-Dihydroxybenzoic acid

: 4-(6-chlorobenzo[d]thiazol-2-yl)benzo hydrazide

: 3-(5-(4-(6-chlorobenzo[d]thiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diol

Conditions

Conditions	Yield
With trichlorophosphate Reflux;	86%

2,3-Dihydroxybenzoic Acid Chemical Properties

Molecular Formula: C₇H₆O₄

Formula Weight: 154.12
mp : 204-206^°C(lit.)
bp of 2,3-Dihydroxybenzoic Acid (303-38-8): 95-96/0.5mm
Flash Point: 187.2 ^°C
density of 2,3-Dihydroxybenzoic Acid (303-38-8): 1,542 g/cm³
Vapour Pressure: 6.85E-06 mmHg at 25^°C
storage temp. : 2-8^°C
Index of Refraction: 1.67
SOLUBILITY IN WATER: Soluble
Appearence of 2,3-Dihydroxybenzoic Acid (303-38-8): Pale Brownish to Red Brownish Crystalline Powder

2,3-Dihydroxybenzoic Acid Uses

2,3-Dihydroxybenzoic Acid (303-38-8) is used as intermediate for pharmaceuticals (especially for antipyetic anlgesic, antirheumatism) and other organic synthesis.
In industrial field, 2,3-Dihydroxybenzoic Acid (303-38-8) is used as intermediate for the production of other organic chemicals, resins, polyesters, plasticizers, dyestuffs, preservatives, and rubber chemicals.

2,3-Dihydroxybenzoic Acid Toxicity Data With Reference

Oral: LD₅₀: >3 gm/kg (rbt)
on the eye: Irritating effect.
on the skin: Irritant to skin and mucous membranes.

2,3-Dihydroxybenzoic Acid Safety Profile

Safety: WARNING: Irritates lungs, eyes, skin
Hazard Codes : Xi (Irritant)
Risk Statements : 36/37/38 (Irritating to eyes, respiratory system and skin)
Safety Statements : 26-36-37/39 (In case of contact with eyes, rinse immediately with plenty of water and seek medical advice; Wear suitable protective clothing; Wear suitable gloves and eye/face protection)
WGK Germany : 2
RTECS : DG8576490
Hazard Note : Irritant

2,3-Dihydroxybenzoic Acid Standards and Recommendations

ASSAY: 99.0% m in
LOSS ON DRYING: 0.5% max
RESIDUE ON IGNITION: 0.1% max

2,3-Dihydroxybenzoic Acid Specification

Storage of 2,3-Dihydroxybenzoic Acid (303-38-8): Store in cool, dry conditions in well sealed containers. Store away from oxidizing agents. Store away from strong bases. Keep container tightly sealed.

Product Name

2,3-Dihydroxybenzoic acid

Synthetic route

2,3-Dihydroxybenzoic Acid Chemical Properties

2,3-Dihydroxybenzoic Acid Uses

2,3-Dihydroxybenzoic Acid Toxicity Data With Reference

2,3-Dihydroxybenzoic Acid Safety Profile

2,3-Dihydroxybenzoic Acid Standards and Recommendations

2,3-Dihydroxybenzoic Acid Specification

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