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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2,5-Dihydroxybenzoic Acid supplier in China

Cas:490-79-9

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:Almost yellow crystalline powder Storage:Store below +30°C Pa

Manufacturer supply 2,5-Dihydroxybenzoic acid CAS 490-79-9 with good quality

Cas:490-79-9

Min.Order:1 Kilogram

FOB Price: $130.0 / 180.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,5-Dihydroxybenzoic Acid

Cas:490-79-9

Min.Order:1

Negotiable

Type:Other

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Jinan Finer Chemical Co., Ltd

Product description: Product name 2,5-Dihydroxybenzoic acid CAS number 490-79-9 Assay ≥99% Appearance White to yellow powder Capacity 200mt/year Application Pharmaceutical i

2,5-Dihydroxybenzoic acid

Cas:490-79-9

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Content Natural Extract 2,5-Dihydroxybenzoic acid HACCP manufacturer

Cas:490-79-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2,5-Dihydroxybenzoic acid Manufacturer/High quality/Best price/In stock

Cas:490-79-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Gentisic acid

Cas:490-79-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc. We are specialized in chemical synthesis, process development of pharmaceu

2,5-Dihydroxybenzoic acid

Cas:490-79-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

2,5-Dihydroxybenzoic acid_

Cas:490-79-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

2,5-Dihydroxybenzoic acid CAS 490-79-9

Cas:490-79-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Best PurityCAS 490-79-9 with high-quality service

Cas:490-79-9

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after the dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available &diam

2,5-Dihydroxybenzoic acid cas490-79-9

Cas:490-79-9

Min.Order:1 Kilogram

FOB Price: $7.0 / 10.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: 2,5-Dihydroxy benzoic acid Synonyms: Gentisic acid; Hydroquinonecarboxylic acid; 5-Hydroxysalicylic acid Molecular Formula: C7H6O4 Molecular Weight: 154.12 CAS Number: 490-79-9 EG/EC Number: 207-718-5 Appearance:White powder Storage:Store in c

2,5-Dihydroxy benzoic acid

Cas:490-79-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzoicacid, 2,5-dihydroxy- 490-79-9

Cas:490-79-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

2,5-Dihydroxy benzoic acid

Cas:490-79-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 2,5-Dihydroxybenzoic acid Synonyms: 2,5-Dhba;2,5-dihydroxy-benzoicaci;2,5-Dioxybenzoic acid;5-Hydroxysalicylic acid;5-hydroxy-salicylicaci;5-hydroxysalicylicacid;acido2,5-diidrossibenzoico;Benzoic acid, 2,5-dihydroxy- CAS: 490-79-9

2,5-Dihydroxybenzoic acid 490-79-9

Cas:490-79-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Animal Pharmaceuticals, 2,5-Dihydroxybenzoic acid CAS:490-79-9

Cas:490-79-9

Min.Order:1 Kilogram

FOB Price: $32.0 / 36.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2,5-Dioxybenzoic acid

Cas:490-79-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

2,5-Dihydroxybenzoic acid

Cas:490-79-9

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzoicacid, 2,5-dihydroxy-

Cas:490-79-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2,5-Dihydroxybenzoic Acid (Dhb)

Cas:490-79-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Chengdu Biopurify Phytochemicals Ltd.

Chengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medic

Gentisic acid

Cas:490-79-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2,5-Dihydroxybenzoic acid

Cas:490-79-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

GENTISIC ACID CAS 490-79-9

Cas:490-79-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,5-Dihydroxybenzoic acid

Cas:490-79-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Transportation:Express/Sea/Air Port:Ningbo/Shanghai/Qingd

2,5-Dihydroxybenzoic acid/Gentisic acid

Cas:490-79-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2,5-Dihydroxybenzoic acid

Cas:490-79-9

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:grey powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:For medicine , pesticide intermediat

2,5-Dihydroxybenzoic acid

Cas:490-79-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2,5-dihydroxybenzoicacid

Cas:490-79-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2,5-Dihydroxybenzoic acid

Cas:490-79-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Synthetic route

2,5-bis-methoxymethoxy-benzoic acid methoxymethyl ester

2,5-bis-methoxymethoxy-benzoic acid methoxymethyl ester

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With methanol; iodine at 20℃; for 48h;96%
5-Allyloxy-2-hydroxy-benzoic acid benzyl ester

5-Allyloxy-2-hydroxy-benzoic acid benzyl ester

A

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

B

3,4-dihydro-5,8-dihydroxy-3-methylisocoumarin
84213-08-1

3,4-dihydro-5,8-dihydroxy-3-methylisocoumarin

C

5-Hydroxy-2-methyl-2,3-dihydro-benzofuran-4-carboxylic acid

5-Hydroxy-2-methyl-2,3-dihydro-benzofuran-4-carboxylic acid

Conditions
ConditionsYield
In trifluoroacetic acid for 17h; Heating;A 25%
B 31%
C 8.5%
benzoic acid
65-85-0

benzoic acid

A

2,3-Dihydroxybenzoic acid
303-38-8

2,3-Dihydroxybenzoic acid

B

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

C

3-Carboxyphenol
99-06-9

3-Carboxyphenol

D

salicylic acid
69-72-7

salicylic acid

E

4-hydroxy-benzoic acid
99-96-7

4-hydroxy-benzoic acid

Conditions
ConditionsYield
With oxygen; iron(II) sulfate In water at 40℃; for 3h; Product distribution; pH 6.8 buffer;A 9%
B 5%
C 14%
D 4%
E 9%
benzoic acid
65-85-0

benzoic acid

A

2,3-Dihydroxybenzoic acid
303-38-8

2,3-Dihydroxybenzoic acid

B

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

C

3-Carboxyphenol
99-06-9

3-Carboxyphenol

D

4-hydroxy-benzoic acid
99-96-7

4-hydroxy-benzoic acid

Conditions
ConditionsYield
With oxygen; iron(II) sulfate In water at 40℃; for 3h; Further byproducts given;A 9%
B 5%
C 14%
D 9%
2,5-Dihydroxybenzaldehyde
1194-98-5

2,5-Dihydroxybenzaldehyde

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With potassium hydroxide durch Schmelzen;
2,5-diacetoxytoluene
717-27-1

2,5-diacetoxytoluene

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With permanganate(VII) ion; magnesium sulfate at 85℃; folgende Verseifung mit Salzsaeure;
5-Aminosalicylic Acid
89-57-6

5-Aminosalicylic Acid

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
Diazotization.Kochen der erhaltenen Diazoverbindung mit Wasser;
2-hydroxy-5-iodobenzoic acid
119-30-2

2-hydroxy-5-iodobenzoic acid

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With potassium hydroxide
2,5-dimethoxybenzoic acid
2785-98-0

2,5-dimethoxybenzoic acid

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With hydrogen bromide
5-bromosalicyclic acid
89-55-4

5-bromosalicyclic acid

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With sodium hydroxide; copper
With sodium hydroxide
5-methoxysalicylic acid
2612-02-4

5-methoxysalicylic acid

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With hydrogen bromide
2-hydroxy-5-formylbenzoic acid
616-76-2

2-hydroxy-5-formylbenzoic acid

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With sodium hydroxide; water
2-carboxy-4-hydroxy-benzenediazonium-betaine

2-carboxy-4-hydroxy-benzenediazonium-betaine

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With sulfuric acid
methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

hydroquinone
123-31-9

hydroquinone

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With potassium carbonate at 140 - 210℃;
hydroquinone
123-31-9

hydroquinone

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With potassium sulfite; water; potassium hydrogencarbonate at 130℃;
With potassium hydrogencarbonate; glycerol at 180℃;
Multi-step reaction with 2 steps
1: NaOH-solution
2: potassium hydroxide / durch Schmelzen
View Scheme
With tetrachloromethane; sodium hydroxide; copper
salicylic acid
69-72-7

salicylic acid

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With phosphate buffer; oxygen; rose bengal Rate constant; Mechanism; Irradiation; other singlet oxygen generating systems; effect of inhibitors;
With potassium peroxomonosulphate Kochen des Reaktionsproduktes mit verd. Salzsaeure;
With dipotassium peroxodisulfate
salicylic acid
69-72-7

salicylic acid

A

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

B

2,3,5-trihydroxybenzoic acid
33580-60-8

2,3,5-trihydroxybenzoic acid

Conditions
ConditionsYield
With sodium hydroxide; ammonium peroxydisulfate
carbon dioxide
124-38-9

carbon dioxide

p-Isopropoxyphenyl methyl ether
20744-02-9

p-Isopropoxyphenyl methyl ether

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
Multistep reaction;
2,5-dihydroxybenzoic acid benzyl ester
21782-87-6

2,5-dihydroxybenzoic acid benzyl ester

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With potassium hydroxide In ethanol Yield given;
salicylic acid
69-72-7

salicylic acid

A

2,3-Dihydroxybenzoic acid
303-38-8

2,3-Dihydroxybenzoic acid

B

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With iron(III)-acetylacetonate; dihydrogen peroxide; methylene blue at 25℃; for 4h; Product distribution; Mechanism; Irradiation; other salicylic derivatives, hydroxylation;
With oxygen; potassium oxalate; iron(III) chloride In water at 25℃; Product distribution; Irradiation; role of hydrogen peroxide in dyoxygen induced hydroxylation of title compound; photochemicall and thermal (pH 7.1) hydroxylation;
With dihydrogen peroxide In water at 20℃; for 0.5h; Mechanism; Product distribution; Quantum yield; Irradiation; various pH value and reaction time, HClO4 or K2CO3 presence;
methylene blue

methylene blue

salicylic acid
69-72-7

salicylic acid

A

2,3-Dihydroxybenzoic acid
303-38-8

2,3-Dihydroxybenzoic acid

B

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With Fe(III)(sal)3(3-); dihydrogen peroxide In water at 25℃; for 1h; Product distribution; Thermodynamic data; Irradiation; other times; presence of O2;
5-(β-D-glucopyranosyloxy)-2-hydroxybenzoic acid
1820-89-9

5-(β-D-glucopyranosyloxy)-2-hydroxybenzoic acid

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With β-glucosidase for 168h; Ambient temperature; enzymatic hydrolysis;

A

2,3-Dihydroxybenzoic acid
303-38-8

2,3-Dihydroxybenzoic acid

B

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With dihydrogen peroxide; potassium carbonate In water at 20℃; for 0.5h; Mechanism; Product distribution; Quantum yield; Irradiation; various pH value and reaction time;
salicylic acid
69-72-7

salicylic acid

A

4-hydroxysalicylic acid
89-86-1

4-hydroxysalicylic acid

B

2,3-Dihydroxybenzoic acid
303-38-8

2,3-Dihydroxybenzoic acid

C

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

D

2,6-Dihydroxybenzoic acid
303-07-1

2,6-Dihydroxybenzoic acid

Conditions
ConditionsYield
With dihydrogen peroxide; iron(II) sulfate In water at 37℃; for 0.0833333h; hydroxylation; Further byproducts given. Title compound not separated from byproducts;
2,5-dihydroxybenzoic acid 2-O-β-4C1-glucopyranoside
98102-34-2

2,5-dihydroxybenzoic acid 2-O-β-4C1-glucopyranoside

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Conditions
ConditionsYield
With hydrogenchloride at 100℃; for 3h; Hydrolysis;
anthracene
120-12-7

anthracene

A

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

B

benzene-1,2-dicarboxylic acid
88-99-3

benzene-1,2-dicarboxylic acid

Conditions
ConditionsYield
In water Oxidation; Formation of xenobiotics; simulated solar irradiation;
hydrogenchloride
7647-01-0

hydrogenchloride

4,7-dihydroxyisoindole-1,3-dione
51674-11-4

4,7-dihydroxyisoindole-1,3-dione

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

6-hydroxy-2,3-dimethyl-chromen-4-one
103988-07-4

6-hydroxy-2,3-dimethyl-chromen-4-one

diluted NaOH-solution

diluted NaOH-solution

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

gentisin
437-50-3

gentisin

potash

potash

A

3,5-dihydroxyphenol
108-73-6

3,5-dihydroxyphenol

B

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

C

acetic acid
64-19-7

acetic acid

Conditions
ConditionsYield
Beim Schmelzen;
1,2,3,4-tetrahydroisoquinoline
635-46-1

1,2,3,4-tetrahydroisoquinoline

sulfuric acid
7664-93-9

sulfuric acid

lead (IV)-oxide-anode

lead (IV)-oxide-anode

A

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

B

oxalic acid
144-62-7

oxalic acid

C

propionic acid
802294-64-0

propionic acid

D

maleic acid
110-16-7

maleic acid

Conditions
ConditionsYield
Electrolysis;
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

meloxicam
71125-38-7

meloxicam

meloxicam gentisic acid
1174325-98-4

meloxicam gentisic acid

Conditions
ConditionsYield
for 0.5h;100%
In tetrahydrofuran Product distribution / selectivity;
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

agomelatine
138112-76-2

agomelatine

agomelatine gentisic acid
1419379-42-2

agomelatine gentisic acid

Conditions
ConditionsYield
In toluene for 0.75h;100%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

methyl iodide
74-88-4

methyl iodide

Methyl 2,5-dihydroxybenzoate
2150-46-1

Methyl 2,5-dihydroxybenzoate

Conditions
ConditionsYield
With potassium hydrogencarbonate In N,N-dimethyl-formamide at 40℃;99%
Stage #1: 2,5-dihydroxybenzoic acid. With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetone for 0.166667h;
Stage #2: methyl iodide In acetone at 20℃; for 4h;
92%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

allyl bromide
106-95-6

allyl bromide

allyl 2,5-bis(allyloxy)benzoate
95731-73-0

allyl 2,5-bis(allyloxy)benzoate

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 1h;99%
Stage #1: 2,5-dihydroxybenzoic acid. With potassium carbonate In N,N-dimethyl-formamide at 0℃; for 0.05h;
Stage #2: allyl bromide In N,N-dimethyl-formamide at 20℃; for 48h;
78%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

pomalidomide
19171-19-8

pomalidomide

(R,S)-4-amino-2-(2,6-dioxo-3-piperidinyl)isoindol-1,3-dione gentisicate

(R,S)-4-amino-2-(2,6-dioxo-3-piperidinyl)isoindol-1,3-dione gentisicate

Conditions
ConditionsYield
In acetonitrile at 20℃; Solvent; Temperature;99%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

boron trifluoride diethyl etherate
109-63-7

boron trifluoride diethyl etherate

ethyl 2,5-dihydroxybenzoate
3943-91-7

ethyl 2,5-dihydroxybenzoate

Conditions
ConditionsYield
at 120℃; for 4h;99%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

1-bromomethyl-4-bromobenzene
589-15-1

1-bromomethyl-4-bromobenzene

2,5-dihydroxy-benzoic acid 4-bromobenzyl ester

2,5-dihydroxy-benzoic acid 4-bromobenzyl ester

Conditions
ConditionsYield
With tetrabutylammomium bromide; potassium hydrogencarbonate In N,N-dimethyl acetamide at 70℃; for 24h; Inert atmosphere;98.4%
With potassium hydrogencarbonate In N,N-dimethyl acetamide at 65℃; for 24h; Inert atmosphere;98.4%
With potassium hydrogencarbonate In N,N-dimethyl-formamide at 70℃; for 24h; Inert atmosphere;78%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

benzyl chloride
100-44-7

benzyl chloride

2,5-dihydroxybenzoic acid benzyl ester
21782-87-6

2,5-dihydroxybenzoic acid benzyl ester

Conditions
ConditionsYield
With potassium carbonate In acetone at 70℃; for 12h;98%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

benzyl bromide
100-39-0

benzyl bromide

2,5-dihydroxybenzoic acid benzyl ester
21782-87-6

2,5-dihydroxybenzoic acid benzyl ester

Conditions
ConditionsYield
With potassium hydrogencarbonate In N,N-dimethyl acetamide at 65℃; for 24h; Inert atmosphere;98%
With sodium hydrogencarbonate In N,N-dimethyl-formamide at 20℃; for 18h;93%
With potassium hydrogencarbonate In N,N-dimethyl-formamide at 40℃;91%
methanol
67-56-1

methanol

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

Methyl 2,5-dihydroxybenzoate
2150-46-1

Methyl 2,5-dihydroxybenzoate

Conditions
ConditionsYield
With sulfuric acid for 48h; Reflux;97%
With sulfuric acid at 25℃; for 12h; Reflux; Inert atmosphere;97%
With 95percent H2SO4 Heating;96%
1-methyl-3-ethyl-4,5-bis(N-methylcarbamoyl)imidazolium benzenesulfonate

1-methyl-3-ethyl-4,5-bis(N-methylcarbamoyl)imidazolium benzenesulfonate

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

1-methyl-3-ethyl-4,5-bis(N-methylcarbamoyl)-imidazolium 2,5-dihydroxybenzoate

1-methyl-3-ethyl-4,5-bis(N-methylcarbamoyl)-imidazolium 2,5-dihydroxybenzoate

Conditions
ConditionsYield
With Amberlite IRA-410 10 (OH(1-)form) In water97%
Mirodenafil

Mirodenafil

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

5-ethyl-2-{5-[4-(2-hydroxy-ethyl)-piperazin-1-ylsulfonyl]-2-n-propoxy-phenyl}-7-n-propyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one gentisate

5-ethyl-2-{5-[4-(2-hydroxy-ethyl)-piperazin-1-ylsulfonyl]-2-n-propoxy-phenyl}-7-n-propyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one gentisate

Conditions
ConditionsYield
In water; acetone at 20℃; for 1h; Product distribution / selectivity;96.5%
In water; acetone at 20℃; Product distribution / selectivity;96.5%
In acetone at 20℃; for 1h; Product distribution / selectivity;77.1%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

allyl bromide
106-95-6

allyl bromide

allyl 5-allyloxy-2-hydroxybenzoate
84213-07-0

allyl 5-allyloxy-2-hydroxybenzoate

Conditions
ConditionsYield
With potassium carbonate In acetone96%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

methyl iodide
74-88-4

methyl iodide

methyl 2,5-dimethoxybenzoate
2150-40-5

methyl 2,5-dimethoxybenzoate

Conditions
ConditionsYield
Stage #1: 2,5-dihydroxybenzoic acid. With sodium hydride In N,N-dimethyl-formamide; mineral oil for 1h; Cooling with ice;
Stage #2: methyl iodide In N,N-dimethyl-formamide; mineral oil at 20℃; for 3h; Cooling with ice;
96%
With potassium carbonate
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

aniline
62-53-3

aniline

2,5-dihydroxy-N-phenylbenzamide
52405-79-5

2,5-dihydroxy-N-phenylbenzamide

Conditions
ConditionsYield
With triphenylphosphine In toluene for 3h; Heating;96%
With phosphorus trichloride In chlorobenzene at 135℃; for 0.333333h; Microwave irradiation;58%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

bosentan
147536-97-8

bosentan

N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-pyrimidin-4-yl]-4-tert-butyl-benzenesulfonamide gentisic acid cocrystal
1450829-49-8

N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-pyrimidin-4-yl]-4-tert-butyl-benzenesulfonamide gentisic acid cocrystal

Conditions
ConditionsYield
In n-heptane; acetone at 55℃; for 2.33333h; Concentration; Solvent; Temperature; Time; Sonication;96%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

(S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-1H-1,2,4-triazol-5(4H)-one

(S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-1H-1,2,4-triazol-5(4H)-one

(S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-1H-1,2,4-triazol-5(4H)-one gentisic acid cocrystal

(S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-1H-1,2,4-triazol-5(4H)-one gentisic acid cocrystal

Conditions
ConditionsYield
With air In acetonitrile at 10 - 35℃; for 120h; Sealed tube;96%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

1-ethyl-7-[[(1S)-1-[4-[(4-prop-2-enoylpiperazin-1-yl)methyl]phenyl]ethyl]amino]-4H-pyrimido[4,5-d][1,3]oxazin-2-one

1-ethyl-7-[[(1S)-1-[4-[(4-prop-2-enoylpiperazin-1-yl)methyl]phenyl]ethyl]amino]-4H-pyrimido[4,5-d][1,3]oxazin-2-one

1-ethyl-7-[[(1S)-1-[4-[(4-prop-2-enoylpiperazin-1-yl)methyl]phenyl]ethyl]amino]-4H-pyrimido[4,5-d][1,3]oxazin-2-one bis(2,5-dihydroxybenzoic acid) salt

1-ethyl-7-[[(1S)-1-[4-[(4-prop-2-enoylpiperazin-1-yl)methyl]phenyl]ethyl]amino]-4H-pyrimido[4,5-d][1,3]oxazin-2-one bis(2,5-dihydroxybenzoic acid) salt

Conditions
ConditionsYield
In ethanol at 48℃;95.62%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

allyl bromide
106-95-6

allyl bromide

allyl 2,5-dihydroxybenzoate
133416-39-4

allyl 2,5-dihydroxybenzoate

Conditions
ConditionsYield
With potassium hydrogencarbonate In N,N-dimethyl-formamide at 70℃;95%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

dimethyl sulfate
77-78-1

dimethyl sulfate

methyl 5-methoxy-2-hydroxybenzoate
2905-82-0

methyl 5-methoxy-2-hydroxybenzoate

Conditions
ConditionsYield
With potassium carbonate In acetone at 50℃; for 30h;94%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

cyclopropylcarbinyl bromide
7051-34-5

cyclopropylcarbinyl bromide

C11H12O4

C11H12O4

Conditions
ConditionsYield
With potassium hydrogencarbonate In N,N-dimethyl-formamide at 70℃;94%
ethanol
64-17-5

ethanol

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

ethyl 2,5-dihydroxybenzoate
3943-91-7

ethyl 2,5-dihydroxybenzoate

Conditions
ConditionsYield
With sulfuric acid for 144h; Heating;93%
With thionyl chloride at 0℃; Reflux; Inert atmosphere;60%
With sulfuric acid
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

benzyl chloride
100-44-7

benzyl chloride

benzyl 2,5-bis(benzyloxy)benzoate
78283-37-1

benzyl 2,5-bis(benzyloxy)benzoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 20h;93%
With potassium carbonate In butanone for 16h; Heating;
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

hexan-1-ol
111-27-3

hexan-1-ol

n-hexyl 2,5-dihydroxybenzoate
37622-50-7

n-hexyl 2,5-dihydroxybenzoate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 9.5h; Heating;93%
With toluene-4-sulfonic acid In toluene at 120℃; for 8h;81.1%
With sulfuric acid Fischer-Speier Esterification;
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

1,3-diphenylpropanedione
120-46-7

1,3-diphenylpropanedione

3-benzoyl-5-hydroxy-2-phenylbenzofuran-4-carboxylic acid

3-benzoyl-5-hydroxy-2-phenylbenzofuran-4-carboxylic acid

Conditions
ConditionsYield
With sodium acetate In water; acetonitrile Electrochemical reaction;93%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

allyl bromide
106-95-6

allyl bromide

5-allyloxy-2-hydroxybenzoic acid
84213-04-7

5-allyloxy-2-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: 2,5-dihydroxybenzoic acid. With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 2h;
Stage #2: allyl bromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 2h;
92.9%
Stage #1: 2,5-dihydroxybenzoic acid. With sodium hydride In N,N-dimethyl-formamide at 20℃; for 2h;
Stage #2: allyl bromide In N,N-dimethyl-formamide at 20℃; for 2h;
Stage #3: With hydrogenchloride In water; N,N-dimethyl-formamide pH=3;
75%
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

dimethyl sulfate
77-78-1

dimethyl sulfate

Methyl 2,5-dihydroxybenzoate
2150-46-1

Methyl 2,5-dihydroxybenzoate

Conditions
ConditionsYield
With sodium hydrogencarbonate; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate at 40℃; for 0.333333h;92%
(S)-(-)-amlodipine-hemi-dibenzoyl-D-tartrate

(S)-(-)-amlodipine-hemi-dibenzoyl-D-tartrate

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

S-amlodipine gentisate
856256-16-1

S-amlodipine gentisate

Conditions
ConditionsYield
Stage #1: (S)-(-)-amlodipine-hemi-dibenzoyl-D-tartrate With sodium hydroxide In dichloromethane; water for 0.5h;
Stage #2: 2,5-dihydroxybenzoic acid. In dichloromethane; acetone at 20℃; for 2h;
92%
(S)-(-)-amlodipine-hemi-dibenzoyl-D-tartrate

(S)-(-)-amlodipine-hemi-dibenzoyl-D-tartrate

2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

S-amlodipine gentisate
856256-16-1

S-amlodipine gentisate

Conditions
ConditionsYield
Stage #1: (S)-(-)-amlodipine-hemi-dibenzoyl-D-tartrate With sodium hydroxide In dichloromethane; water for 0.5h;
Stage #2: 2,5-dihydroxybenzoic acid. In dichloromethane; acetone at 20℃; for 2h;
92%

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