2,4-Dichlorotoluene supplier

Name
2,4-Dichlorotoluene
EINECS 202-445-8
CAS No. 95-73-8
Article Data46
CAS DataBase
Density 1.242 g/cm³
Solubility immiscible with water
Melting Point -14 °C
Formula C₇H₆Cl₂
Boiling Point 198.6 °C at 760 mmHg
Molecular Weight 161.031
Flash Point 79.4 °C
Transport Information UN 2810
Appearance clear colorless liquid
Safety 23-24/25
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Toluene,2,4-dichloro- (8CI);1,3-Dichloro-4-methylbenzene;2,4-Dichloro-1-methylbenzene;
PSA 0.00000
LogP 3.30180

Synthetic route

: 1777-82-8
(2,4-dichlorophenyl)methanol

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With 2-pentanol; ReOCl3(SMe2)(OPPh3) for 17h; Green chemistry; chemoselective reaction;	98%
Multi-step reaction with 3 steps 1: diethylamino-sulfur trifluoride / dichloromethane / 1 h / -78 - 20 °C 2: tris(pentafluorophenyl)borate / 1,2-dichloro-ethane / 0.08 h / 20 °C / Glovebox; Schlenk technique 3: sodium tetrahydroborate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 18 h / 20 °C View Scheme

: 1193-72-2
1-bromo-2,4-dichlorobenzene

: 544-97-8
dimethyl zinc(II)

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In 1,4-dioxane for 2h; Heating;	91%

: 874-42-0
2,4-dichlorobenzaldeyhde

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With 2-pentanol; ReOCl3(SMe2)(OPPh3) for 17h; Green chemistry; chemoselective reaction;	91%

: 95-80-7
4-methylbenzene-1,3-diamine

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With potassium bisulfite; potassium chloride; cobalt(II) chloride In water at 70 - 75℃; for 2.33333h; Concentration; Temperature;	85%
With nitrosylsulfuric acid; acetic acid Behandlung der erhaltenen Diazoniumsalz-Loesung mit CuCl in konz. wss. HCl;
With hydrogenchloride; copper dichloride; sodium nitrite

: 59293-67-3
2,4-dichlorobenzyl mercaptan

A: 95-73-8
2,4-dichlorotoluene

B: 6295-41-6
bis-(2,4-dichloro-benzyl)-sulfide

C: 874-42-0
2,4-dichlorobenzaldeyhde

D: 1,2-bis(2',4'-dichlorophenyl)ethane

Conditions

Conditions	Yield
With tetrafluoroboric acid; triiron dodecarbonyl In benzene 1.) RT, 4 h; 2.) 60 deg C;	A 74% B 2% C 3% D 10%

...Expand

: 106-43-4
para-chlorotoluene

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With aluminum (III) chloride; iron(III) chloride; chlorine; calcium chloride; zinc(II) chloride In water at 39℃; for 18h; Temperature; Molecular sieve; Autoclave; Inert atmosphere;	68.9%
With chlorine at 40 - 41℃; for 0.5h; Temperature;	68%
With perchloric acid; trichloroisocyanuric acid In water; acetic acid at 30℃; Rate constant; Thermodynamic data; Ea, ΔH(excit.), ΔS(excit.);

: 50-84-0
2,4 dichlorobenzoic acid

A: 1777-82-8
(2,4-dichlorophenyl)methanol

B: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With tricarbonyl(η(4)-cycloocta-1,5-diene)iron; phenylsilane In tetrahydrofuran at 20℃; for 24h; Inert atmosphere; UV-irradiation; chemoselective reaction;	A 67% B n/a

: 59293-67-3
2,4-dichlorobenzyl mercaptan

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
dicobalt octacarbonyl In water; benzene at 185 - 190℃; under 46543.3 Torr;	63%

: 108-88-3
toluene

A: 106-43-4
para-chlorotoluene

B: 95-49-8
2-methylchlorobenzene

C: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With hydrogenchloride; sodium hypochlorite In water at 20℃; Product distribution; Further Variations:; Temperatures; molar quantity of reagents; Chlorination; oxidative chlorination;	A 29% B 63% C 3.5%
With oxone; potassium chloride In acetonitrile at 20℃; for 24h; Product distribution; Further Variations:; Reagents ratio;
With sulfuric acid; [BMIM]Cl; chlorine at 70℃; for 8h;

...Expand

: C32H24Cl2N(1+)*BF4(1-)

A: 95-73-8
2,4-dichlorotoluene

B: 60211-56-5
2,4-dichlorobenzyl fluoride

Conditions

Conditions	Yield
at 180℃; under 0.5 Torr; for 3h;	A 20% B 45%

: 59293-67-3
2,4-dichlorobenzyl mercaptan

A: 95-73-8
2,4-dichlorotoluene

B: 6295-41-6
bis-(2,4-dichloro-benzyl)-sulfide

C: 874-42-0
2,4-dichlorobenzaldeyhde

Conditions

Conditions	Yield
With tetrafluoroboric acid; triiron dodecarbonyl In benzene 1.) RT, 4 h; 2.) 60 deg C;	A 41% B 32% C 3%

...Expand

: 30895-98-8
4-methylphenyltellurium trichloride

A: 106-43-4
para-chlorotoluene

B: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With oxygen In benzene at 20 - 30℃; for 4h; Irradiation;	A 36% B 2%

: 50-84-0
2,4 dichlorobenzoic acid

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With dimethylsulfide borane complex In chlorobenzene 1) 15 min, r.t. 2) 4 h, reflux;	25%

: 95-00-1
2,4-dichloro-benzenemethanamine

A: 95-73-8
2,4-dichlorotoluene

B: 60211-56-5
2,4-dichlorobenzyl fluoride

Conditions

Conditions	Yield
at 200℃; under 2 Torr; for 3h;	A 5% B 20%

: 108-88-3
toluene

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With sulfuric acid; sodium chloride; sodium periodate In water; acetonitrile at 80℃; for 6h;	15%
With iron(III) chloride beim Chlorieren;
With molybdenum(V) chloride beim Chlorieren;

: 106-43-4
para-chlorotoluene

A: 95-75-0
3,4-Dichlorotoluene

B: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
bei der Chlorierung;
With aluminium; mercury durch Chlorieren;
With iodine; chlorine

: 95-49-8
2-methylchlorobenzene

A: 19398-61-9
2,5-dichlorotoluene

B: 118-69-4
2,6-dichlorotoluene

C: 95-73-8
2,4-dichlorotoluene

D: 32768-54-0
2,3-dichlorotoluene

Conditions

Conditions	Yield
bei der Chlorierung;
With sulfuric acid; 1-butyl-3-methylimidazolium chloroaluminate; chlorine at 30℃; for 12h; Reagent/catalyst; Temperature;
With sulfuric acid; chlorine at 35℃; for 12h; Temperature; Molecular sieve;

...Expand

: 95-49-8
2-methylchlorobenzene

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With iron(III) chloride beim Chlorieren;
With molybdenum(V) chloride beim Chlorieren;

: 95-74-9
3-chloro-p-toluidine

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
Diazotization.Behandlung der Diazoniumchloridloesung mit Cuprochlorid;

: 119-32-4
4-Methyl-3-nitroanilin

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
Austausch der NH2-Gruppe gegen Chlor, Reduktion und Ersatz der neu gebildeten NH2-Gruppe durch Chlor;

: 59293-67-3
2,4-dichlorobenzyl mercaptan

A: 95-73-8
2,4-dichlorotoluene

B: 6295-41-6
bis-(2,4-dichloro-benzyl)-sulfide

C: 188065-31-8
2,4-dichloro-1-{[(2,4-dichlorobenzyl)disulfanyl]methyl}benzene

Conditions

Conditions	Yield
With sodium hydroxide; triiron dodecarbonyl; tetra(n-butyl)ammonium hydrogensulfate In water; benzene at 60℃; for 16h;	A 95 % Chromat. B 3 % Chromat. C 2 % Chromat.
With sodium hydroxide; triiron dodecarbonyl; tetra(n-butyl)ammonium hydrogensulfate In water; benzene at 60℃; for 16h;	A 95 % Chromat. B 3 % Chromat. C 2 % Chromat.

...Expand

: 7647-01-0
hydrogenchloride

: 7732-18-5
water

: 64-19-7
acetic acid

: 108-88-3
toluene

A: 106-43-4
para-chlorotoluene

B: 95-49-8
2-methylchlorobenzene

C: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
im Dunkeln an Platin-Anoden mit einer Stromdichte von 0.005 Amp./cm2.Electrolysis;

...Expand

: 106-43-4
para-chlorotoluene

iron: iron

A: 95-75-0
3,4-Dichlorotoluene

B: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
at 20℃; sowie bei 40grad; Chlorierung;

...Expand

2.4-dichloro-toluene-sulfonic acid-(3)-amide: 2.4-dichloro-toluene-sulfonic acid-(3)-amide

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With steam; sulfuric acid at 230 - 240℃;
With phosphoric acid; steam at 230 - 240℃;

2.4-dichlorotoluene-sulfonic acid-(3): 2.4-dichlorotoluene-sulfonic acid-(3)

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With steam; sulfuric acid at 230 - 240℃;
With phosphoric acid; steam at 230 - 240℃;

4.6-dichloro-toluene-sulfonic acid-(2): 4.6-dichloro-toluene-sulfonic acid-(2)

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With steam; sulfuric acid at 230 - 240℃;
With phosphoric acid; steam at 230 - 240℃;

4.6-dichloro-toluene-sulfonic acid-(3): 4.6-dichloro-toluene-sulfonic acid-(3)

: 95-73-8
2,4-dichlorotoluene

Conditions

Conditions	Yield
With steam; sulfuric acid at 230 - 240℃;
With phosphoric acid; steam at 230 - 240℃;

: 7647-01-0
hydrogenchloride

: 95-80-7
4-methylbenzene-1,3-diamine

copper chloride: copper chloride

sodium nitrite: sodium nitrite

: 95-73-8
2,4-dichlorotoluene

...Expand

: 81156-68-5
2,4-dichlorophenylethyl alcohol

A: 95-73-8
2,4-dichlorotoluene

B: 2123-27-5
2,4-dichlorostyrene

C: 6-chloro-2,3-dihydrobenzofuran

Conditions

Conditions	Yield
Stage #1: 2,4-dichlorophenylethyl alcohol With sodium hydride In pyridine at 40℃; for 0.25h; Metallation; Stage #2: copper(l) chloride In pyridine for 4h; Cyclization; Ullman reaction; Heating;

...Expand

: 95-73-8
2,4-dichlorotoluene

: 6425-26-9
2,4-dichloro-1-(dibromomethyl)benzene

Conditions

Conditions	Yield
With sodium bromate; hydrogen bromide In water at 65℃; for 0.333333h; Flow reactor; Irradiation; Green chemistry;	99%
With hydrogen bromide; sodium bromide In chloroform; water at 5 - 15℃; Electrolysis;	85%
With N-Bromosuccinimide; dibenzoyl peroxide In tetrachloromethane Reflux;	84%
With bromine

: 95-73-8
2,4-dichlorotoluene

: 933-88-0
ortho-toluoyl chloride

: (2,4-Dichloro-5-methyl-phenyl)-o-tolyl-methanone

Conditions

Conditions	Yield
With aluminium trichloride In carbon disulfide for 240h; Heating;	92%

: 95-73-8
2,4-dichlorotoluene

: 7149-77-1
1,5-dichloro-2-methyl-4-nitrobenzene

Conditions

Conditions	Yield
With nitric acid In 1,2-dichloro-ethane at 30 - 35℃; for 2h; Temperature; Reagent/catalyst;	91%
With sulfuric acid; nitric acid at -10℃;	80%
With sodium nitrate; sulfuric acid at 40℃; for 3h;	43%

: 95-73-8
2,4-dichlorotoluene

: 75-36-5
acetyl chloride

: 77344-73-1
2,4-dichloro-5-methylacetophenone

Conditions

Conditions	Yield
With aluminium trichloride In carbon disulfide for 18h; Heating;	90%

: 95-73-8
2,4-dichlorotoluene

: 98-88-4
benzoyl chloride

: 16444-45-4
2,4-dichloro-5-methyl-benzophenone

Conditions

Conditions	Yield
With aluminium trichloride In carbon disulfide for 72h; Heating;	89%
With carbon disulfide; aluminium trichloride

: 95-73-8
2,4-dichlorotoluene

: 94-99-5
2,4-Dichlorobenzyl chloride

Conditions

Conditions	Yield
With N-chloro-succinimide; N-hydroxyphthalimide; 2,3-dicyano-5,6-dichloro-p-benzoquinone In acetonitrile at 80℃; for 16h; Time; Sealed tube; Inert atmosphere;	89%
With 2,2'-azobis(isobutyronitrile); chlorine at 110℃; for 3h;	79.2%
With thionyl chloride; dibenzoyl peroxide

: 95-73-8
2,4-dichlorotoluene

: 1711-06-4
3-Methylbenzoyl chloride

: (2,4-Dichloro-5-methyl-phenyl)-m-tolyl-methanone

Conditions

Conditions	Yield
With aluminium trichloride In carbon disulfide for 96h; Heating;	89%

: 95-73-8
2,4-dichlorotoluene

: 50-84-0
2,4 dichlorobenzoic acid

Conditions

Conditions	Yield
Stage #1: 2,4-dichlorotoluene With tert.-butylhydroperoxide; sodium hydroxide; tungsten(VI) oxide In water at 80℃; for 10h; Stage #2: With hydrogenchloride In water	83%
With sodium bromate; sulfuric acid; sodium bromide In water at 100℃; for 7h; Irradiation;	82%
With manganese(IV) oxide; sulfuric acid at 80℃;

: 95-73-8
2,4-dichlorotoluene

: 874-42-0
2,4-dichlorobenzaldeyhde

Conditions

Conditions	Yield
With dipotassium peroxodisulfate; ferrocene; iron(II) acetylacetonate In water; acetonitrile at 80℃; for 9h;	80%
With sodium molybdate; dihydrogen peroxide; cobalt(II) acetate; acetic acid; sodium bromide at 105℃; for 0.166667h; Temperature; Flow reactor;	30.1%
With bromine at 180 - 200℃; Erhitzen des Reaktionsgemisches mit konz. Schwefelsaeure auf 100-140grad;

: 95-73-8
2,4-dichlorotoluene

: 106-54-7
p-Chlorothiophenol

: S-(4-chlorophenyl) 2,4-dichlorobenzothioate

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; sodium dodecyl-sulfate; iron(II) bromide In water at 100℃; for 24h;	79%

: 124-38-9
carbon dioxide

: 95-73-8
2,4-dichlorotoluene

A: 118-90-1
ortho-methylbenzoic acid

B: 5162-82-3
3-chloro-4-methylbenzoic acid

C: 7499-06-1
5-chloro-2-methylbenzoic acid

D: 99-94-5
p-Toluic acid

Conditions

Conditions	Yield
With tetrabutylammomium bromide In N,N-dimethyl-formamide at 5℃; electrolysis (I=0.4 A); Further byproducts given. Yields of byproduct given;	A n/a B n/a C n/a D 78%
With tetrabutylammomium bromide In N,N-dimethyl-formamide at 5℃; electrolysis (I=0.4 A); Yield given. Further byproducts given. Yields of byproduct given;

...Expand

: 95-73-8
2,4-dichlorotoluene

: 123-11-5
4-methoxy-benzaldehyde

: 899664-15-4
2,4-dichlorobenzyl 4-methoxybenzoate

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; copper(II) acetate dihydrate In decane at 100℃; for 5h;	78%

: 95-73-8
2,4-dichlorotoluene

: 6574-98-7
2,4-dichlorobenzylnitrile

Conditions

Conditions	Yield
With ammonia at 390℃; Reagent/catalyst;	77.3%
With bismuth(III) vanadate; ammonia at 440℃; under 760.051 Torr; Catalytic behavior; Temperature;	72.2%
With ammonia; oxygen; DC-108 at 400℃; Yield given;

: 95-73-8
2,4-dichlorotoluene

: 5188-07-8
sodium thiomethoxide

A: 53250-85-4
3-Chloro-4-methylphenyl methyl sulphide

B: 82961-51-1
4-chloro-2-(methylsulphenyl)toluene

Conditions

Conditions	Yield
In N,N,N,N,N,N-hexamethylphosphoric triamide at 100℃; for 0.75h;	A 6% B 76%

...Expand

: 95-73-8
2,4-dichlorotoluene

: 28286-86-4
2,4-dichloro-5-methyl-benzenesulfonyl chloride

Conditions

Conditions	Yield
With chlorosulfonic acid at 60℃; for 3h;	75%
With chlorosulphuric acid
With chlorosulfonic acid
With chlorosulphuric acid

: 95-73-8
2,4-dichlorotoluene

: 56843-28-8
2,4-dichlorobenzaldoxime

Conditions

Conditions	Yield
With tert.-butylnitrite; N-hydroxyphthalimide; copper diacetate In acetonitrile at 80℃; for 24h; Inert atmosphere;	75%

: 95-73-8
2,4-dichlorotoluene

: 20277-69-4
sodium methansulfinate

: 1671-18-7
4-methylsulfonyl-1-methyl-2-chlorobenzene

Conditions

Conditions	Yield
With potassium phosphate; copper(l) iodide; (2S,4R)-4-hydroxy-N-(2-methylnaphthalen-1-yl)pyrrolidine-2-carboxamide In dimethyl sulfoxide at 120℃; Sealed tube; Inert atmosphere;	74%

: 95-73-8
2,4-dichlorotoluene

: 100-52-7
benzaldehyde

: 899663-73-1
2,4-dichlorobenzyl benzoate

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; copper(II) acetate dihydrate In decane at 100℃; for 6h;	71%

: 95-73-8
2,4-dichlorotoluene

: 20607-43-6
sodium isopropanethiolate

: 87544-09-0
2,4-bis(i-propylthio)toluene

Conditions

Conditions	Yield
In N,N,N,N,N,N-hexamethylphosphoric triamide at 100℃; for 20h;	69.5%

: 745783-97-5
triethyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane

: 95-73-8
2,4-dichlorotoluene

: C13H17BCl2O2

Conditions

Conditions	Yield
With C34H28ClF12IrN2Si In methyl cyclohexane at 100℃; for 16h; Inert atmosphere; Glovebox;	68%

: 95-73-8
2,4-dichlorotoluene

: 115615-19-5
1-bromo-3,5-dichloro-2-toluene

Conditions

Conditions	Yield
With bromine; iron(III) chloride In tetrachloromethane for 0.25h;	67%
With iron(III) chloride; bromine In tetrachloromethane at 20℃; for 0.5h; Inert atmosphere;	67%
With N-Bromosuccinimide In dichloromethane at 0 - 20℃; for 12h;	50%
With FeCl3; bromine In tetrachloromethane

: 95-73-8
2,4-dichlorotoluene

: 19433-17-1
acetophenone O-acetyloxime

: 1286729-10-9
4-(2',4'-dichlorophenyl)-2,6-diphenylpyridine

Conditions

Conditions	Yield
With [bis(acetoxy)iodo]benzene; copper(II) bis(trifluoromethanesulfonate) In toluene at 100℃; for 8h;	64%

2,4-Dichlorotoluene Chemical Properties

The Molecular Structure of 2,4-Dichlorotoluene (CAS NO.95-73-8):

Empirical Formula: C₇H₆Cl₂
Molecular Weight: 161.0285
Index of Refraction: 1.543
Molar Refractivity: 40.86 cm³
Molar Volume: 129.6 cm³
Surface Tension: 35.6 dyne/cm
Density: 1.242 g/cm³
Flash Point: 79.4 °C
Enthalpy of Vaporization: 41.71 kJ/mol
Boiling Point: 198.6 °C at 760 mmHg
Vapour Pressure: 0.502 mmHg at 25°C
IUPAC Name: 2,4-dichloro-1-methylbenzene
Appearance: clear colorless liquid
Product Categories: Organics;Aryl;C7;Halogenated Hydrocarbons
Synonyms: 2,4-Dichlorotoluene ; 2,4-Dichloro-1-methylbenzene ; 4-05-00-00815 (Beilstein Handbook Reference) ; BRN 1931691 ; Benzene, 2,4-dichloro-1-methyl- ; EINECS 202-445-8 ; HSDB 2567 ; Toluene, 2,4-dichloro- ; Benzene, 2,4-dichloro-1-methyl- ; Toluene, 2,4-dichloro-

2,4-Dichlorotoluene Uses

2,4-Dichlorotoluene (CAS NO.95-73-8) is used as raw materials for organic synthesis. In medicine industry, 2,4-Dichlorotoluene (CAS NO.95-73-8) is used as high boiling point solvents and for the synthesis of chlorinated-nitrated pesticides and medicinal products. For pesticide intermediates, It is used for manufacture 2,4-dichloro-benzyl chloride , 2,4-Dichlorobenzoyl chloride for synthesis and 2,4-dichloro-benzoic acid .

2,4-Dichlorotoluene Production

Through 2.3-chloro-4-toluidine and sodium nitrate's diazo reaction, then through the sandmyer-reaction with copper chloride, we can obtain 2,4-Dichlorotoluene (CAS NO.95-73-8).

2,4-Dichlorotoluene Toxicity Data With Reference

1.	orl-rat LD50:4600 mg/kg	GISAAA Gigiena i Sanitariya. 53 (2)(1988),80.
2.	orl-mus LD50:2900 mg/kg	GISAAA Gigiena i Sanitariya. 53 (2)(1988),80.
3.	orl-gpg LD50:5 g/kg	GISAAA Gigiena i Sanitariya. 53 (2)(1988),80.

2,4-Dichlorotoluene Consensus Reports

Reported in EPA TSCA Inventory.

2,4-Dichlorotoluene Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 23-24/25
S23: Do not breathe vapour
S24/25: Avoid contact with skin and eyes
RIDADR: UN 2810
WGK Germany: 2
RTECS: XT0730000
Hazard Note: Harmful
HazardClass: 9
PackingGroup: III
HS Code: 29036990

2,4-Dichlorotoluene Standards and Recommendations

ASSAY: 99.0% min
ISOMER IMPURITY: 1.0% max

Product Name

2,4-Dichlorotoluene

Synthetic route

2,4-Dichlorotoluene Chemical Properties

2,4-Dichlorotoluene Uses

2,4-Dichlorotoluene Production

2,4-Dichlorotoluene Toxicity Data With Reference

2,4-Dichlorotoluene Consensus Reports

2,4-Dichlorotoluene Safety Profile

2,4-Dichlorotoluene Standards and Recommendations

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