2,6-Dichlorophenylacetic acid supplier

Name
2,6-Dichlorophenylacetic acid
EINECS 229-504-0
CAS No. 6575-24-2
Article Data15
CAS DataBase
Density 1.456 g/cm³
Solubility
Melting Point 159-162 °C
Formula C₈H₆Cl₂O₂
Boiling Point 325.2 °C at 760 mmHg
Molecular Weight 205.04
Flash Point 150.5 °C
Transport Information
Appearance white crystalline powder
Safety 37/39-26-36
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Aceticacid, (2,6-dichlorophenyl)- (6CI,7CI,8CI);2,6-Dichlorobenzeneacetic acid;2-(2,6-Dichlorophenyl)acetic acid;
PSA 37.30000
LogP 2.62050

Synthetic route

: 3776-30-5
2,2,6,6-tetrachlorocyclohexanone

: 105-53-3
diethyl malonate

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

Conditions

Conditions	Yield
Stage #1: 2,2,6,6-tetrachlorocyclohexanone; diethyl malonate With 1,8-diazabicyclo[5.4.0]undec-7-ene In 1,2-dichloro-ethane at 60 - 65℃; for 3h; Stage #2: With sodium hydroxide In 1,2-dichloro-ethane at 20 - 65℃; for 3h; Solvent; Temperature; Reagent/catalyst;	96.6%

: 90793-64-9
ethyl 2-(2,6-dichlorophenyl)acetate

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

Conditions

Conditions	Yield
With water; sodium hydroxide In 1,4-dioxane at 60℃; for 2h; pH=10 - 14;	95%

: 201230-82-2
carbon monoxide

: 2014-83-7
1,3-Dichloro-2-chloromethyl-benzene

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

Conditions

Conditions	Yield
With bis-triphenylphosphine-palladium(II) chloride; tetraethylammonium chloride; sodium hydroxide In 5,5-dimethyl-1,3-cyclohexadiene at 80℃; under 11251.1 Torr; for 20h; Autoclave; regioselective reaction;	93%

: 3215-64-3
2,6-dichlorophenylacetonitrile

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

Conditions

Conditions	Yield
Stage #1: 2,6-dichlorophenylacetonitrile With potassium hydroxide; water In ethanol at 80℃; for 20h; Stage #2: With hydrogenchloride In ethanol pH=3;	83%
With sodium hydroxide
With potassium hydroxide In ethylene glycol

etheric 2.6-dichloro-benzyl magnesium chloride: etheric 2.6-dichloro-benzyl magnesium chloride

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

Conditions

Conditions	Yield
Einleiten von Kohlendioxid;

: 124-38-9
carbon dioxide

: 118-69-4
2,6-dichlorotoluene

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

Conditions

Conditions	Yield
Stage #1: 2,6-dichlorotoluene With lithium diisopropyl amide In tetrahydrofuran; cyclohexane at -75℃; for 0.75h; Stage #2: carbon dioxide In tetrahydrofuran; cyclohexane

: 124-38-9
carbon dioxide

: 118-69-4
2,6-dichlorotoluene

A: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

B: 39652-34-1
3,5-dichloro-4-methylbenzoic acid

C: 83277-23-0
2,4-Dichloro-3-methyl-benzoic acid

Conditions

Conditions	Yield
Stage #1: 2,6-dichlorotoluene With sec.-butyllithium In tetrahydrofuran; cyclohexane at -75℃; for 0.75h; Stage #2: carbon dioxide In tetrahydrofuran; cyclohexane Title compound not separated from byproducts;

...Expand

: 2014-83-7
1,3-Dichloro-2-chloromethyl-benzene

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: dimethylsulfoxide / 5 h / 40 - 50 °C 2: 25 percent NaOH / ethanol / Heating View Scheme
Multi-step reaction with 2 steps 2: aqueous NaOH View Scheme
Multi-step reaction with 2 steps 2: H2SO4 View Scheme

: 118-69-4
2,6-dichlorotoluene

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: dichloro[4,5-bis(diphenylphosphino)-9,9’-dimethylxanthene]palladium(II); di-tert-butyl peroxide / 16 h / 120 °C / 7600.51 Torr 2: water; sodium hydroxide / 1,4-dioxane / 2 h / 60 °C / pH 10 - 14 View Scheme

: 608-31-1
2,6-Dichloroaniline

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium nitrite; sulfuric acid; copper(I) bromide; tetrabutylammomium bromide / water / 2 h / -5 - 95 °C 2: hydrogenchloride / 10 h / 80 - 95 °C / Inert atmosphere View Scheme

: 30359-34-3
1-(2,2,2-trichloroethyl)-2,6-dichlorobenzene

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

Conditions

Conditions	Yield
With hydrogenchloride at 80 - 95℃; for 10h; Inert atmosphere;	115.3 g

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 61875-53-4
2,6-dichlorophenylacetylchloride

Conditions

Conditions	Yield
With thionyl chloride In toluene at 20℃; for 12h;	100%
With thionyl chloride at 80℃; for 1h;	90%
With thionyl chloride

: 7719-09-7
thionyl chloride

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 880089-70-3
1-bromo-3-(2,6-dichlorophenyl)propan-2-one

Conditions

Conditions	Yield
Stage #1: thionyl chloride; 2-(2,6-dichlorophenyl)acetic acid With diazomethyl-trimethyl-silane Stage #2: With hydrogen bromide In water	100%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 2-(2,6-dichlorophenyl)(1,1-2H2)ethan-1-ol

Conditions

Conditions	Yield
With borane-d3 In tetrahydrofuran at 0 - 20℃; for 20h;	99%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 4-[(1S,3R)-3-[[tert-butyl(dimethyl)silyl]oxymethyl]-1-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl]-2-methyl-butan-2-ol

: 1-[(1S,3R)-3-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl]-2-(2,6-dichlorophenyl)ethanone

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; 1,1'-carbonyldiimidazole In tetrahydrofuran	98%
Stage #1: 2-(2,6-dichlorophenyl)acetic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran at 25℃; for 1h; Stage #2: 4-[(1S,3R)-3-[[tert-butyl(dimethyl)silyl]oxymethyl]-1-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl]-2-methyl-butan-2-ol In tetrahydrofuran at 45℃; for 24h; Reagent/catalyst;	376 g
Stage #1: 2-(2,6-dichlorophenyl)acetic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran at 25℃; for 1h; Stage #2: 4-[(1S,3R)-3-[[tert-butyl(dimethyl)silyl]oxymethyl]-1-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl]-2-methyl-butan-2-ol In tetrahydrofuran at 25 - 45℃; for 24h;	376 g
With N-ethyl-N,N-diisopropylamine; 1,1'-carbonyldiimidazole In tetrahydrofuran at 40℃; for 72h; Inert atmosphere;	250 mg

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 30595-79-0
2-(2,6-dichlorophenyl)ethan-1-ol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether for 12h; Heating;	97%
With lithium aluminium tetrahydride In diethyl ether for 16h; Heating / reflux;	85%
With borane In tetrahydrofuran at 0 - 20℃; Inert atmosphere;	73%
With lithium aluminium tetrahydride In diethyl ether
With borane In tetrahydrofuran

: 21715-90-2
endo-N-hydroxy-5-norbornene-2,3-dicarboxyimide

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 2,6-Dichloro-benzoic acid (1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide	97%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 2-(2,6-dichlorophenyl)(2H2)acetic acid

Conditions

Conditions	Yield
With deuteriated sodium hydroxide; tetrabutylammomium bromide In water-d2 at 105℃; for 40h;	97%

: 67-56-1
methanol

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 54551-83-6
methyl 2-(2,6-dichlorophenyl)acetate

Conditions

Conditions	Yield
With sulfuric acid	96%
With hydrogenchloride Reflux;	92%
With thionyl chloride at 0℃; Reflux;	10 g
With sulfuric acid for 8h; Reflux;

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 80518-57-6
ethyl 4-(piperazin-1-yl)benzoate

: 1092069-59-4
C21H22Cl2N2O3

Conditions

Conditions	Yield
With diethyl cyanophosphonate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;	95%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: (1S,3R)-5-bromo-3-(((tertbutyldiphenylsilyl) oxy)methyl)-1-methyl-1,2,3,4-tetrahydroisoquinoline

: 1-[(1S,3R)-5-bromo-3-[[tert-butyl(diphenyl)silyl]oxymethyl]-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl]-2-(2,6-dichlorophenyl)ethanone

Conditions

Conditions	Yield
Stage #1: 2-(2,6-dichlorophenyl)acetic acid; (1S,3R)-5-bromo-3-(((tertbutyldiphenylsilyl) oxy)methyl)-1-methyl-1,2,3,4-tetrahydroisoquinoline With trimethylamine In acetonitrile for 0.0833333h; Stage #2: With propylphosphonic anhydride In ethyl acetate; acetonitrile at 5 - 20℃; for 1.25h;	93%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 129564-34-7
2-(2,6-dichlorophenyl)acetohydrazide

Conditions

Conditions	Yield
With 1,1'-carbonyldiimidazole; hydrazine In tetrahydrofuran	92%
With 1,1'-carbonyldiimidazole; hydrazine In tetrahydrofuran	92%
Stage #1: 2-(2,6-dichlorophenyl)acetic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran Stage #2: With hydrazine In tetrahydrofuran Further stages.;

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 95-54-5
1,2-diamino-benzene

: 743451-08-3
2-(2,6-dichlorobenzyl)-1H-benzo[d]imidazole

Conditions

Conditions	Yield
With polyphosphoric acid at 175℃; for 4h; Inert atmosphere;	92%
With polyphosphoric acid for 4h; Inert atmosphere; Heating;	92%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 95-83-0
4-Chloro-1,2-phenylenediamine

: 1274937-60-8
5-chloro-2-(2,6-dichlorobenzyl)-1H-benzo[d]imidazole

Conditions

Conditions	Yield
With polyphosphoric acid for 4h; Inert atmosphere; Heating;	92%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 83-38-5
2,6-dichlorobenzaldehyde

Conditions

Conditions	Yield
With 1H-imidazole; C17H16ClMnN2O2; tetrabutylammonium periodite In chloroform at 20℃; for 0.666667h;	90%
With 1H-imidazole; [bis(acetoxy)iodo]benzene; Co(AAOPD) In acetonitrile at 20℃; for 6.33333h;	89%
With mercury(II) fluoride; oxygen In acetonitrile at 25℃; for 24h; Irradiation;	76%
With oxygen; mercury(II) oxide In methanol; acetonitrile at 25℃; UV-irradiation;	64%
With dihydrogen peroxide In water; acetonitrile at 25℃; for 10h; UV-irradiation;	12.5 %Chromat.

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 20443-98-5
2,6-Dichlorobenzyl bromide

Conditions

Conditions	Yield
With silver triflate-bis(1,10-phenanthroline) complex; dibromoisocyanuric acid In 1,2-dichloro-ethane at 20℃; for 22h; Inert atmosphere; Schlenk technique;	88%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: (1S)-5-bromo-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride

: 1-[(1S)-5-bromo-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl]-2-(2,6-dichlorophenyl)ethanone

Conditions

Conditions	Yield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In dichloromethane at 20℃;	86%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 2014-83-7
1,3-Dichloro-2-chloromethyl-benzene

Conditions

Conditions	Yield
With tert-butylhypochlorite; silver triflate-bis(1,10-phenanthroline) complex In acetonitrile at 20℃; for 26h; Inert atmosphere;	85%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 4-[(1S,3R)-3-(hydroxymethyl)-1-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl]-2-methyl-butan-2-ol

: 2-(2,6-dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one

Conditions

Conditions	Yield
Stage #1: 4-[(1S,3R)-3-(hydroxymethyl)-1-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl]-2-methyl-butan-2-ol With 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine In acetonitrile at 0℃; for 0.5h; Stage #2: 2-(2,6-dichlorophenyl)acetic acid In acetonitrile at 0℃; for 1h;	85%
Stage #1: 2-(2,6-dichlorophenyl)acetic acid With 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine In acetonitrile at 0℃; for 1h; Stage #2: 4-[(1S,3R)-3-(hydroxymethyl)-1-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl]-2-methyl-butan-2-ol With potassium carbonate In water; acetonitrile at 0℃; for 4h; Solvent;	85%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 2-fluoro-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)methyl]benzenamine

: 2-(2,6-dichlorophenyl)-N-{2-fluoro-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)methyl]phenyl}acetamide

Conditions

Conditions	Yield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In tetrahydrofuran; ethyl acetate at 20℃; for 2h; Alkaline conditions;	85%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: (1S,3R)-3-(((tert-butyldimethylsilyl)oxy)methyl)-1-methyl-5-(1-(oxetan-3-yl)-1H-pyrazol-4-yl)-1,2,3,4-tetrahydroisoquinoline

: 1-((1S,3R)-3-(((tert-butyldimethylsilyl)oxy)methyl)-1-methyl-5-(1-(oxetan-3-yl)-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-2(1H)-yl)-2-(2,6-dichlorophenyl)ethan-1-one

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane for 2h;	84%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: (1S,3R)-5-bromo-3-(([tert-butyl(dimethyl)silyl]oxy)methyl)-1-methyl-1,2,3,4-tetrahydroisoquinoline

: 1-[(1S,3R)-5-bromo-3-[[tert-butyl(dimethyl)silyl]oxymethyl]-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl]-2-(2,6-dichlorophenyl)ethan-1-one

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide	83%
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; for 3h;	55%
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; for 3h;	4.70 g
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; for 3h;	4.7 g

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine

: 318294-29-0
2-(2,6-dichloro-phenyl)-N-[2-(3,4-dimethoxy-phenyl)-ethyl]-acetamide

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile for 6h; Condensation; Heating;	82%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 4-amino-N-(4-methoxycyclohexyl)-1H-pyrazole-3-carboxamide

: 4-(2-(2,6-dichlorophenyl)acetamido)-N-(4-methoxycyclohexyl)-1H-pyrazole-3-carboxamide

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere;	81%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 100-46-9
benzylamine

: 849098-26-6
1-benzyl-4-chloro-1,3-dihydroindol-2-one

Conditions

Conditions	Yield
Stage #1: 2-(2,6-dichlorophenyl)acetic acid; benzylamine at 150℃; for 0.5h; microwave irradiation; Stage #2: With sodium hydroxide; XPhos; palladium diacetate In water; toluene at 100℃; for 0.5h; microwave irradiation;	80%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 106670-33-1
β-(3-chlorobenzyl)mercaptoethylamine

: 1234381-00-0
N-[2-(3-chlorobenzylsulfanyl)ethyl]-2-(2,6-dichlorophenyl)acetamide

Conditions

Conditions	Yield
Stage #1: 2-(2,6-dichlorophenyl)acetic acid With dicyclohexyl-carbodiimide In dichloromethane for 0.5h; Inert atmosphere; Stage #2: β-(3-chlorobenzyl)mercaptoethylamine With triethylamine In dichloromethane at 20℃; for 1h; Inert atmosphere;	80%
Stage #1: 2-(2,6-dichlorophenyl)acetic acid With dicyclohexyl-carbodiimide In dichloromethane for 0.5h; Inert atmosphere; Stage #2: β-(3-chlorobenzyl)mercaptoethylamine With triethylamine In dichloromethane at 20℃; for 1h; Inert atmosphere;	80%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 4-(4-aminobenzyl)-5-(dibromomethylene)furan-2(5H)-one

: N-(4-((2-(dibromomethylene)-5-oxo-2,5-dihydrofuran-3-yl)methyl)phenyl)-2-(2,6-dichlorophenyl)acetamide

Conditions

Conditions	Yield
With pyridine In dichloromethane at 0 - 20℃;	78%

2,6-Dichlorophenylacetic acid Specification

The Benzeneaceticacid, 2,6-dichloro-, with the CAS registry number 6575-24-2, is also known as 2,6-Dichlorobenzeneacetic acid. It belongs to the product categories of Acids and Derivatives; Aromatic Phenylacetic Acids and Derivatives; Phenylacetic acid; C₈; Carbonyl Compounds; Carboxylic Acids. Its EINECS number is 229-504-0. This chemical's molecular formula is C₈H₆Cl₂O₂ and formula weight is 205.04. What's more, its IUPAC name is 2-(2,6-dichlorophenyl)acetic acid.

Physical properties of Benzeneaceticacid, 2,6-dichloro- are: (1)ACD/LogP: 2.71; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.01; (4)ACD/LogD (pH 7.4): -0.66; (5)ACD/BCF (pH 5.5): 1.34; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 14.08; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 26.3 Å²; (13)Index of Refraction: 1.584; (14)Molar Refractivity: 47.15 cm³; (15)Molar Volume: 140.7 cm³; (16)Surface Tension: 51.6 dyne/cm; (17)Density: 1.456 g/cm³; (18)Flash Point: 150.5 °C; (19)Enthalpy of Vaporization: 59.89 kJ/mol; (20)Boiling Point: 325.2 °C at 760 mmHg; (21)Vapour Pressure: 9.54E-05 mmHg at 25°C.

Uses of Benzeneaceticacid, 2,6-dichloro-: it can be used to produce 2,6-dichloro-benzaldehyde at the temperature of 25°C. It will need reagent HgF₂, O₂ and solvent acetonitrile with reaction time of 24 hours. The yield is about 76%.

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin. You need wear suitable gloves and eye/face protection. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Besides, you must wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1=CC(=C(C(=C1)Cl)CC(=O)O)Cl
(2)InChI: InChI=1S/C8H6Cl2O2/c9-6-2-1-3-7(10)5(6)4-8(11)12/h1-3H,4H2,(H,11,12)
(3)InChIKey: SFAILOOQFZNOAU-UHFFFAOYSA-N

Product Name

2,6-Dichlorophenylacetic acid

Synthetic route

2,6-Dichlorophenylacetic acid Specification

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