3,5,6-Trichlorosalicylic acid supplier

Name
3,5,6-Trichlorosalicylic acid
EINECS 255-144-9
CAS No. 40932-60-3
Article Data9
CAS DataBase
Density 1.772 g/cm³
Solubility It has limited solubility in water.
Melting Point 209-211 °C(lit.)
Formula C₇H₃Cl₃O₃
Boiling Point 335 °C at 760 mmHg
Molecular Weight 241.458
Flash Point 156.4 °C
Transport Information
Appearance white grey solid powder
Safety 26-37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Salicylicacid, 3,5,6-trichloro- (7CI);2,3,5-Trichloro-6-hydroxybenzoic acid;3,5,6-Trichloro-2-hydroxybenzoic acid;3,5,6-Trichlorosalicylic acid;
PSA 57.53000
LogP 3.05060

Synthetic route

: 320-72-9
3,5-dichlorosalicylic acid

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

Conditions

Conditions	Yield
With sulfuric acid; iodine; chlorine at 70℃;	93%
With sulfuric acid; iodine; chlorine at 40 - 70℃; for 6h;	81%
With sulfuric acid; chlorine

: 320-72-9
3,5-dichlorosalicylic acid

A: 87-87-6
2,3,5,6-tetrachlorobenzene-1,4-diol

B: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

C: 118-75-2
chloranil

D: tri(3,5,6-trichlorosalicylide)

Conditions

Conditions	Yield
With sulfuric acid; chlorine at 80 - 90℃; for 15h;	A 3.5% B 44% C 10.8% D 19%
With sulfuric acid; chlorine at 80 - 90℃; for 15h;	A 3.5% B 44% C 10.8% D n/a

...Expand

: 7664-93-9
sulfuric acid

: 320-72-9
3,5-dichlorosalicylic acid

: 7782-50-5
chlorine

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

...Expand

: 321-14-2
5-chloro-2-hydroxybenzoic acid

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: chlorine / acetic acid / Ambient temperature 2: 81 percent / 65percent oleum, iodine, chlorine / 6 h / 40 - 70 °C View Scheme

: 89-55-4
5-bromosalicyclic acid

A: 2200-85-3
5-bromo-3-chloro-2-hydroxybenzoic acid

B: 4-bromo-3,6-dichlorosalicylic acid

C: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

Conditions

Conditions	Yield
With trichloroisocyanuric acid; sulfuric acid; iodine at 0 - 70℃; for 5h;

...Expand

: 69-72-7
salicylic acid

A: 2200-85-3
5-bromo-3-chloro-2-hydroxybenzoic acid

B: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: bromine; sulfuric acid / 1 h / 20 - 60 °C 2: iodine; trichloroisocyanuric acid; sulfuric acid / 5 h / 0 - 70 °C View Scheme
Multi-step reaction with 2 steps 1: bromine; sulfuric acid / 1 h / 20 °C 2: iodine; trichloroisocyanuric acid; sulfuric acid / 5 h / 0 - 70 °C View Scheme
Multi-step reaction with 2 steps 1: bromine; sulfuric acid; acetic acid / 0.5 h / 30 - 60 °C 2: iodine; trichloroisocyanuric acid; sulfuric acid / 5 h / 0 - 70 °C View Scheme
Multi-step reaction with 2 steps 1: bromine; sulfuric acid; acetic acid / 2 h / 30 °C 2: iodine; trichloroisocyanuric acid; sulfuric acid / 5 h / 0 - 70 °C View Scheme

: 89-55-4
5-bromosalicyclic acid

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: chlorine; sulfuric acid / 8.5 h / 3 - 45 °C 2: chlorine; iodine; sulfuric acid / 3.5 h / 5 - 35 °C View Scheme

: 69-72-7
salicylic acid

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: bromine; sulfuric acid / 1.5 h / 3 - 25 °C 2: chlorine; sulfuric acid / 8.5 h / 3 - 45 °C 3: chlorine; iodine; sulfuric acid / 3.5 h / 5 - 35 °C View Scheme

: 2200-85-3
5-bromo-3-chloro-2-hydroxybenzoic acid

A: 4-bromo-3,6-dichlorosalicylic acid

B: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

C: 3-bromo-6-((3-bromo-2,5-dichloro-6-hydroxybenzoyl)oxy)-2,5-dichlorobenzoic acid

Conditions

Conditions	Yield
With sulfuric acid; iodine; chlorine at 5 - 35℃; for 3.5h;

...Expand

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

: 100-49-2
cyclohexylmethyl alcohol

: C14H15Cl3O3

Conditions

Conditions	Yield
titanium (IV) oxide bis(2,4-pentanedionate) In xylene Reflux;	99%

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

: 100-46-9
benzylamine

: C7H9N*C7H3Cl3O3

Conditions

Conditions	Yield
In methanol for 0.0833333h;	83.19%

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

: 1066-45-1
trimethyltin(IV)chloride

: C7HCl3O3(2-)*2Sn(4+)*6CH3(1-)

Conditions

Conditions	Yield
With sodium ethanolate In methanol at 40℃; for 12h; Inert atmosphere;	77%

: 1122-58-3
dmap

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

: C7H10N2*C7H3Cl3O3

Conditions

Conditions	Yield
In methanol; ethanol	77%

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

: 100-51-6
benzyl alcohol

: 1330007-24-3
C14H9Cl3O3

Conditions

Conditions	Yield
titanium (IV) oxide bis(2,4-pentanedionate) In toluene Reflux;	76.5%

: cadmium(II) perchlorate hydrate

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

: N'-(amino(pyrimidin-2-yl)methylene)-3-(pyridin-2-yl)-1H-pyrazole-5-carbohydrazide

: 2C7H2Cl3O3(1-)*4C7H3Cl3O3*5H2O*9Cd(2+)*8C14H10N8O(2-)

Conditions

Conditions	Yield
In methanol; N,N-dimethyl-formamide at 80℃; for 12h;	74%

...Expand

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

: 1461-22-9
tributyltin chloride

: C7HCl3O3(2-)*2Sn(4+)*6C4H9(1-)

Conditions

Conditions	Yield
With sodium ethanolate In methanol at 40℃; for 12h; Inert atmosphere;	72%

: 108-73-6
3,5-dihydroxyphenol

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

: 5,7,8-trichloro-1,3-dihydroxyxanthone

Conditions

Conditions	Yield
With methanesulfonic acid; phosphorus pentoxide at 90℃; for 0.333333h; Temperature;	72%

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

: 71-36-3
butan-1-ol

: 30431-49-3
butyl 3,5,6-trichlorosalicylate

Conditions

Conditions	Yield
With sulfuric acid for 24h; Heating;	67%

: 504-15-4
orcinol

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

: 1,2,4-trichloro-8-hydroxy-6-methyl-9H-xanthen-9-one

Conditions

Conditions	Yield
With methanesulfonic acid; phosphorus pentoxide at 90℃;	66%

: 1291-32-3
zirconocene dichloride

: 40932-60-3
3,5,6-Trichloro-2-hydroxybenzoic acid

: [Cp2Zr(μ2-O',O''C-C6H(OH)Cl3)2]

Conditions

Conditions	Yield
In hydrogenchloride; dichloromethane mixt. of zirconocene dichloride in 1 M aq. HCl and dichlorobenzoic acidin CH2Cl2 was stirred for 30 min at room temp.; organic layer was separated, dried over MgSO4, filtered, concd. in vac.,crystd. form CH2Cl2/hexane, elem. anal.;	64.4%