3-Chloropicolinic acid supplier

Name
3-Chloropicolinic acid
EINECS
CAS No. 57266-69-0
Article Data7
CAS DataBase
Density 1.47 g/cm³
Solubility
Melting Point 148-150 °C
Formula C₆H₄ClNO₂
Boiling Point 297.6 °C at 760 mmHg
Molecular Weight 157.556
Flash Point 133.8 °C
Transport Information
Appearance off-white solid
Safety 26
Risk Codes 22-36
Molecular Structure
Hazard Symbols Xi,Xn
Synonyms 3-Chloro-2-pyridinecarboxylicacid;
PSA 50.19000
LogP 1.43320

Synthetic route

: lithium; 3-chloro-pyridine-2-carboxylate

: 57266-69-0
3-chloropyridine-2-carboxylic acid

Conditions

Conditions	Yield
With Amberlyst(R) IR-200 In methanol at 20℃; for 0.25h;	53%

: 72093-03-9
3-chloro-2-methylpyridine

: 57266-69-0
3-chloropyridine-2-carboxylic acid

Conditions

Conditions	Yield
With potassium permanganate for 21.5h; Heating;	45%

: 1462-86-8
3-amino-pyridine-2-carboxylic acid

: 57266-69-0
3-chloropyridine-2-carboxylic acid

Conditions

Conditions	Yield
With hydrogenchloride; sodium nitrite Anschliessend Behandeln mit CuCl;

: 57841-92-6
3-chloropicolinanilide

: 57266-69-0
3-chloropyridine-2-carboxylic acid

Conditions

Conditions	Yield
With hydrogenchloride for 15h; Heating;

: 98-98-6
2-Picolinic acid

: 57266-69-0
3-chloropyridine-2-carboxylic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: BuLi; 2,2,6,6-tetramethylpiperidine / tetrahydrofuran; hexane / 0.67 h / -75 - 0 °C 1.2: 72 percent / hexachloroethane / tetrahydrofuran; hexane / 0 - 20 °C 2.1: 53 percent / Amberlyst(R) IR-200 / methanol / 0.25 h / 20 °C View Scheme

: 10354-53-7
N-phenylpicolinamide

: 57266-69-0
3-chloropyridine-2-carboxylic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1.) n-BuLi, 2.) CCl3CCl3 / 1.) THF, -78 deg C - 0.5 h, room temperature - 1 h, 2.) THF, -78 deg C - 1 h, room temperature - 2 h 2: aq. HCl / 15 h / Heating View Scheme

: 38180-46-0
3-chloro-2-cyanopyridine

: 57266-69-0
3-chloropyridine-2-carboxylic acid

Conditions

Conditions	Yield
In methanol; sodium hydroxide; dichloromethane
With sodium hydroxide at 95℃; for 2h; pH=2-3;

: 1702-17-6
Clopyralid

A: 98-98-6
2-Picolinic acid

B: 57266-69-0
3-chloropyridine-2-carboxylic acid

Conditions

Conditions	Yield
With Graphite; sodium hydroxide In water at 25℃; for 3h; Electrolysis;
With Graphite; sodium hydroxide In water at 25℃; for 6h; pH=11.5 - 13.5; Reagent/catalyst; pH-value; Electrolysis;

: 462-08-8
pyridin-3-ylamine

: 57266-69-0
3-chloropyridine-2-carboxylic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: hydrogenchloride; dihydrogen peroxide / water / 2 h / 5 °C 1.2: 0.42 h / -5 °C 1.3: 1.33 h / 15 - 30 °C 2.1: hydrazine hydrate / ethanol / 6 h / Reflux; Inert atmosphere 3.1: sodium hydroxide / 2 h / 95 °C / pH 2-3 View Scheme

: 2402-77-9
2,3-dichloro-pyridine

: 57266-69-0
3-chloropyridine-2-carboxylic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: hydrazine hydrate / ethanol / 6 h / Reflux; Inert atmosphere 2: sodium hydroxide / 2 h / 95 °C / pH 2-3 View Scheme

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 2-[5-amino-2-[(1r,4r)-4-(hydroxymethyl)cyclohexyl]indazol-6-yl]propan-2-ol

: 3-chloro-N-[2-[(1r,4r)-4-(hydroxymethyl)cyclohexyl]-6-(1-hydroxy-1-methyl-ethyl)indazol-5-yl]pyridine-2-carboxamide

Conditions

Conditions	Yield
With 2-chloro-1-methyl-pyridinium iodide; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 1h; Inert atmosphere;	89%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: (3aR,5s,6aS)-2-(5-bromopyridin-2-yl)-5-methyloctahydrocyclopenta[c]pyrrol-5-amine

: N-((3aR,5s,6aS)-2-(5-bromopyridin-2-yl)-5-methyloctahydrocyclopenta[c]pyrrol-5-yl)-3-chloropicolinamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 40℃; for 2h;	81%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 2402-77-9
2,3-dichloro-pyridine

Conditions

Conditions	Yield
With tert-butylhypochlorite; dichloromethane; sodium hydrogencarbonate at 60℃; for 20h; Green chemistry;	80%
With tert-butylhypochlorite; sodium carbonate; sodium chloride In dichloromethane at 30℃; for 20h; Schlenk technique;	50%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 96424-68-9
2-bromo-3-chloropyridine

Conditions

Conditions	Yield
With tert-butylhypochlorite; dichloromethane; oxygen; sodium hydrogencarbonate at 70℃; for 20h; Green chemistry;	80%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 4-(6-(4-amino-4-methylpiperidin-1-yl)pyridin-3-yl)-6-hydroxypyrazolo[1,5-a]pyridine-3-carbonitrile dihydrochloride

: 4-(6-(4-amino-4-methylpiperidin-1-yl)pyridin-3-yl)-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile dihydrochloride

Conditions

Conditions	Yield
With N-[(dimethylamino)-1H-1,2,3-triazolo[4,5-b]pyridine-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide; N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 20℃;	76%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 4-(6-((1R,5S,6s)-6-(aminomethyl)-3-azabicyclo[3.1.0]hexan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile hydrochloride

: 3-chloro-N-(((1R,5S,6s)-3-(5-(3-cyano-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-3-azabicyclo[3.1.0]hexan-6-yl)methyl)picolinamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 80℃; for 1h;	76%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 825-41-2
3-chloro-4-nitroaniline

: N-(3-chloro-4-nitrophenyl)-3-chloropicolinamide

Conditions

Conditions	Yield
Stage #1: 3-chloropyridine-2-carboxylic acid With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane for 0.0833333h; Stage #2: 3-chloro-4-nitroaniline In dichloromethane; N,N-dimethyl-formamide at 120℃; for 0.5h; Microwave irradiation;	75%

: 123-91-1
1,4-dioxane

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 3–chloro–2–(2–(2–chloroethoxy)ethoxy)pyridine

Conditions

Conditions	Yield
With tert-butylhypochlorite; chloranil at 110℃; for 12h; Inert atmosphere;	75%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 64-17-5
ethanol

: ethyl 3-Chloro-2-pyridinecarboxylate

Conditions

Conditions	Yield
With sulfuric acid for 3h; Reflux;	72%
With sulfuric acid for 3h; Reflux;

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 4-(5-((3aR,5s,6aS)-5-amino-5-methylhexahydrocyclopenta[c]pyrrol-2(1H)-yl)pyrazin-2-yl)-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile

: 3-chloro-N-((3aR,5s,6aS)-2-(5-(3-cyano-6-ethoxypyrazolo[1,5-a]pyridin-4-yl)pyrazin-2-yl)-5-methyloctahydrocyclopenta[c]pyrrol-5-yl)picolinamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 40℃; for 2h;	70%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 4-(6-(4-amino-4-methylpiperidin-1-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile

: 3-chloro-N-(1-(5-(3-cyano-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-4-methylpiperidin-4-yl)picolinamide

Conditions

Conditions	Yield
With N-[(dimethylamino)-1H-1,2,3-triazolo[4,5-b]pyridine-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h;	68%

: 100-42-5
styrene

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 2-chloro-1-phenylethyl 3-chloropicolinate

Conditions

Conditions	Yield
With tert-butylhypochlorite In tetrahydrofuran at 25℃; for 6h; Schlenk technique;	63%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 749875-32-9
3-chloro-2-(trifluoromethyl)pyridine

Conditions

Conditions	Yield
With sulfur tetrafluoride; hydrogen fluoride at 85℃; for 24h; Autoclave; Inert atmosphere;	54%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 4-(5-((1R,3S,5s,7s)-5-amino-2-azaadamantan-2-yl)pyrazin-2-yl)-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile

: 3-chloro-N-((1R,3S,5s,7s)-2-(5-(3-cyano-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl)pyrazin-2-yl)-2-azaadamantan-5-yl)picolinamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 4h;	52%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 64-18-6
formic acid

: 3-[4-[4-[[(1r,4r)-4-(5-amino-6-methoxy-indazol-2-yl)cyclohexyl]methyl-methyl-amino]-1-piperidyl]-3-methyl-2-oxo-benzimidazol-1-yl]piperidine-2,6-dione

: 3-chloro-N-[2-[(1r,4r)-4-[[[1-[1-(2,6-dioxo-3-piperidyl)-3-methyl-2-oxo-benzimidazol-4-yl]-4-piperidyl]-methyl-amino]methyl]cyclohexyl]-6-methoxy-indazol-5-yl]pyridine-2-carboxamide formate

Conditions

Conditions	Yield
Stage #1: 3-chloropyridine-2-carboxylic acid; 3-[4-[4-[[(1r,4r)-4-(5-amino-6-methoxy-indazol-2-yl)cyclohexyl]methyl-methyl-amino]-1-piperidyl]-3-methyl-2-oxo-benzimidazol-1-yl]piperidine-2,6-dione With 2-chloro-1-methyl-pyridinium iodide; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 2h; Inert atmosphere; Stage #2: formic acid In water; acetonitrile Inert atmosphere;	51%

...Expand

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 1617524-08-9
N-(2-(7-methoxynaphthalen-1-yl)ethyl)azetidine-3-carboxamide hydrochloride

: 1-(3-chloroisonicotinoyl)-N-(2-(7-methoxynaphthalen-1-yl)ethyl)azetidine-3-carboxamide

Conditions

Conditions	Yield
With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane; N,N-dimethyl-formamide at 20℃; for 24h;	50%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 4-(6-((3aR,5r,6aS)-5-amino-5-methylhexahydrocyclopenta[c]pyrrol-2(1H)-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile hydrochloride

: 3-chloro-N-((3aR,5r,6aS)-2-(5-(3-cyano-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-5-methyloctahydrocyclopenta[c]pyrrol-5-yl)picolinamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 2h;	48%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 60588-81-0
3-chloro-2-hydroxy-methyl-pyridine

Conditions

Conditions	Yield
Stage #1: 3-chloropyridine-2-carboxylic acid With isopropyl chloroformate; triethylamine In tetrahydrofuran at 0 - 20℃; for 1h; Stage #2: With sodium tetrahydroborate at 20℃; for 2h;	47%
Multi-step reaction with 2 steps 1: Et3N / tetrahydrofuran / 0.5 h / 5 °C 2: aq. NaBH4 / tetrahydrofuran / 4 h / 25 °C View Scheme

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 71-43-2
benzene

: 634198-21-3
2-phenyl-3-chloropyridine

Conditions

Conditions	Yield
With tert-butylhypochlorite; potassium carbonate at 60℃; for 20h;	45%

: 110-91-8
morpholine

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: (3-chloropyridin-2-yl)(morpholino)methanone

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide at 20℃;	43%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: ((1R,5S,6s)-3-(5-bromopyridin-2-yl)-3-azabicyclo[3.1.0]hexan-6-yl) methanamine hydrochloride

: N-(((1R,5S,6s)-3-(5-bromopyridin-2-yl)-3-azabicyclo[3.1.0]hexan-6-yl)methyl)-3-chloropicolinamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 75℃; for 2h;	39%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 4-(6-((3aR,5s,6aS)-5-aminohexahydrocyclopenta[c]pyrrol-2(1H)-yl)pyridin-3-yl)-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile hydrochloride

: 3-chloro-N-((3aR,5s,6aS)-2-(5-(3-cyano-6-ethoxypyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)octahydrocyclopenta[c]pyrrol-5-yl)picolinamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 60℃; for 2h;	38%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 4-(6-((1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile hydrochloride

: 3-chloro-N-((1R,5S,6s)-3-(5-(3-cyano-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-3-azabicyclo[3.1.0]hexan-6-yl)picolinamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 45℃;	31%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 4-(6-((1R,5S,6s)-6-(aminomethyl)-3-azabicyclo[3.1.0]hexan-3-yl)pyridin-3-yl)-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile TFA salt

: 3-chloro-N-(((1R,5S,6s)-3-(5-(3-cyano-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-3-azabicyclo[3.1.0]hexan-6-yl)methyl)picolinamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In tetrahydrofuran at 60℃; for 6h;	27%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 4-(6-((1R,3S,5s,7s)-5-amino-2-azaadamantan-2-yl)pyridin-3-yl)-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile hydrochloride

: 3-chloro-N-((1R,3S,5s,7s)-2-(5-(3-cyano-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-2-azaadamantan-5-yl)picolinamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 50℃;	24%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 4-(5-((1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl)pyrazin-2-yl)-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile hydrochloride

: 3-chloro-N-((1R,5S,6s)-3-(5-(3-cyano-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl)pyrazin-2-yl)-3-azabicyclo[3.1.0]hexan-6-yl)picolinamide

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 2h;	21%

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 2-(2-chlorophenyl)cyclobutanamine

: 3-chloro-N-[(1,2-cis)-2-(2-chlorophenyl)cyclobutyl]pyridine-2-carboxamide

: trans-3-chloro-N-[2-(2-chlorophenyl)cyclobutyl]pyridine-2-carboxamide

Conditions

Conditions	Yield
With triethylamine; HATU In dichloromethane at 20℃; for 3h;	A 20.8% B 18.9%

...Expand

: 57266-69-0
3-chloropyridine-2-carboxylic acid

: 863600-81-1
tert-butyl (3aS,6aR)-5-amino-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxylate

: (3aR,5r,6aS)-tert-butyl 5-(3-chloropicolinamido) hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 50℃; for 1.5h;	20%

3-Chloropicolinic acid Specification

The 3-Chloropicolinic acid has the cas register number 57266-69-0. And it has other names as iflab-bb f1926-0037; 3-chloropyridine-2-carboxylic acid; 3-chloropicolinic acid; 3-chloropyridine-2-carboxylicacid98%; 3-chloro-2-pyridinecarboxylic; 3-chloro-2-picolinic acid.

The physical properties of this chemical are as followings: (1)ACD/LogP: 0.30 ; (2)ACD/BCF (pH 5.5): 1; (3)ACD/BCF (pH 7.4): 1; (4)ACD/KOC (pH 5.5): 1; (5)ACD/KOC (pH 7.4): 1; (6)#H bond acceptors: 3; (7)#H bond donors: 1; (8)#Freely Rotating Bonds: 1; (9)Polar Surface Area: 39.19 ; (10)Index of Refraction: 1.59; (11)Molar Refractivity: 36.16 cm³; (12)Molar Volume: 107.1 cm³; (13)Polarizability: 14.33×10^-24cm³; (14)Surface Tension: 61 dyne/cm; (15)Density: 1.47 g/cm³; (16)Flash Point: 133.8 °C; (17)Enthalpy of Vaporization: 56.76 kJ/mol; (18)Boiling Point: 297.6 °C at 760 mmHg; (19)Vapour Pressure: 0.000599 mmHg at 25°C.

This is a kind of off-white solid, and it is usually used as a useful synthetic intermediate. Being among the irritant chemicals, it is irritant to the eyes, and it may cause inflammation to the skin or other mucous membranes. Besides, it is harmful if swallowed and it may also cause damage to health. So when you contact with this chemical, you should be very cautious and had better take the following instructions. If in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

This kind of chemical is usually applied in BPC(bulk pharmaceutical chemicals) and the medical intermediates. As to its raw materials, there are various, including hydrochloric acid, ethyl acetate, sulfuric acid , toluene, sodium nitrite, potassium permanganate, zinc, 6-chloro-2-methyl-3-nitropyridine, 3-amino-2-picoline; While its product categories are pharmacetical; pyridine; aromatics; pyridines.

In addition, you could obtain the molecular structure by converting the following datas:
SMILES:Clc1cccnc1C(=O)O
InChI:InChI=1/C6H4ClNO2/c7-4-2-1-3-8-5(4)6(9)10/h1-3H,(H,9,10)
InChIKey:XTMUXJBJCMRWPG-UHFFFAOYAF

Product Name

3-Chloropicolinic acid

Synthetic route

3-Chloropicolinic acid Specification

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