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Tianjin Kind Pharma Co., Ltd.

Factory direct sales, accept customization. 2,3-Dichloropyridine is used as a reagent for the preparation of substituted 3-(5-membered heterocycle-carboxamido)pyridine derivatives for treatment of autoimmune and inflammatory diseases. Also in the sy

2,3-Dichloropyridine

Cas:2402-77-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2,3-Dichloropyridine Manufacturer/High quality/Best price/In stock

Cas:2402-77-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance White to off-white solid Off-White Solid Melting point 65.0℃. -6

High purity Various Specifications 2,3-Dichloropyridine CAS:2402-77-9

Cas:2402-77-9

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2,3-Dichloropyridine supplier in China

Cas:2402-77-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White to light yellow solid Storage:Store at RT. Package:1kg/

Manufacturer supply 2,3-Dichloropyridine CAS 2402-77-9 at favorable price

Cas:2402-77-9

Min.Order:5 Kilogram

FOB Price: $50.0 / 100.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:OLED Intermediate Transportation:by air or by sea Port:shanghai

2,3-Dichloropyridine

Cas:2402-77-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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EAST CHEMSOURCES LIMITED

2,3-Dichloropyridine Cas No.:2402-77-9 Molecular Structure: 1. Product Name: 2,3-Dichloropyridine, 99% min. 2. Cas No.: 2402-77-9 3. EINECS No.: 219-281-8 4. Molecular Formula: C5H3Cl2N 5. M.W: 147.99 6. Properties:

2,3-Dichloropyridine

Cas:2402-77-9

Min.Order:1 Kilogram

FOB Price: $2.0 / 3.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,3-dichloropyridine

Cas:2402-77-9

Min.Order:1

Negotiable

Type:Other

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Wuhan Kemi-Works Chemical Co., Ltd

1.We have been specializing in special fine chemical for long, with strong R&D strength. 2.ISO9001. 3.We have been cooperating with oversea from Europe, USA, Korea, Japan etc... Appearance:- Storage:store in dry and cool place Package:

2,3-Dichloropyridine

Cas:2402-77-9

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 2,3-Dichloropyridine 2402-77-9 ISO Producer

Cas:2402-77-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

2,3-Dichloropyridine

Cas:2402-77-9

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

2,3-Dichloropyridine

Cas:2402-77-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,3-Dichloropyridine

Cas:2402-77-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

2,3-dichloropyridine

Cas:2402-77-9

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--2402-77-9--2,3-Dichloropyridine in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business relati

TIANFUCHEM--2402-77-9--2,3-Dichloropyridine in stock

Cas:2402-77-9

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/1649.html Product Name 2,3-Dichloropyridine CAS No. 2402-77-9

2,3-Dichloropyridine

Cas:2402-77-9

Min.Order:1 Metric Ton

FOB Price: $5.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2, 3-Dichloropyridine CAS 2402-77-9

Cas:2402-77-9

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 2402-77-9 with best quality

Cas:2402-77-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

2,3-Dichloropyridine

Cas:2402-77-9

Min.Order:10 Kilogram

FOB Price: $40.0 / 50.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

2,3-Dichloropyridine CAS2402-77-9

Cas:2402-77-9

Min.Order:1 Kilogram

FOB Price: $7.0 / 9.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

2,3-Dichloropyridine/ LIDE PHARMA- Factory supply / Best price

Cas:2402-77-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Product: 2,3-Dichloropyridine Content: ≥99% CAS No: 2402-77-9 Melting point 64-

2,3-Dichloropyridine CAS: 2402-77-9

Cas:2402-77-9

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White powder Storage:R.T Package:25kg/drum Application:Pesticide/Pharmaceutical Intermediate Transportation:Express/Sea/Air Port:Any port in China

2,3-Dichloropyridine cas 2402-77-9

Cas:2402-77-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best serv

2,3-Dichloropyridine Manufacturer For Pesticide Intermediates

Cas:2402-77-9

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Hangzhou Think Chemical Co. Ltd

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exporting

2,3-Dichloropyridine

Cas:2402-77-9

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,3-Dichloropyridine 2402-77-9

Cas:2402-77-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

About us Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad.

2,3-Dichloropyridine

Cas:2402-77-9

Min.Order:1 Kilogram

FOB Price: $80.0 / 90.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

C5H3Cl2N Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, steroids, pharma

C5H3Cl2N

Cas:2402-77-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2,3-Dichloropyridine

Cas:2402-77-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:2402-77-9

Cas:2402-77-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2,3,4,6-Tetrachloropyridine
14121-36-9

2,3,4,6-Tetrachloropyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With hydrogen; triethylamine; urea; citric acid In ethyl acetate at 50℃; under 7500.75 Torr; for 7h; Solvent; Temperature; Pressure; Reagent/catalyst; Autoclave;98.1%
2,3,6-trichloropyridine
6515-09-9

2,3,6-trichloropyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With carbonylhydridetris(triphenylphosphine)rhodium(I); hydrogen; triethylamine In methanol at 60℃; under 450045 Torr; Temperature; Solvent; Pressure; Autoclave;98%
With methanol; palladium 10% on activated carbon; 3-p-menthene at 60℃; for 4h; Temperature; Reagent/catalyst;95%
With hydrogen In methanol at 75℃; under 750.075 Torr; for 8h; Reagent/catalyst; Autoclave;95.3%
2,6-dichloropyridine
2402-78-0

2,6-dichloropyridine

A

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

B

2,6-difluoro pyridine
1513-65-1

2,6-difluoro pyridine

Conditions
ConditionsYield
In dimethyl sulfoxideA 96.3%
B n/a
2-chloro-3-aminopyridine
6298-19-7

2-chloro-3-aminopyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
Stage #1: 2-chloro-3-aminopyridine With hydrogenchloride; sodium nitrite In water at 5 - 15℃; for 0.75h;
Stage #2: With hydrogenchloride; aminosulfonic acid; copper(II) chloride dihydrate In water at 55 - 62℃; Product distribution / selectivity;
95%
With hydrogenchloride; thionyl chloride; nitric acid In water at 0 - 5℃;91%
With hydrogenchloride; sodium nitrite In water at -5 - 40℃; for 1h; Sandmeyer Reaction; Cooling with ice; Inert atmosphere;83%
2-hydroxy-3-chloropyridine
13466-35-8

2-hydroxy-3-chloropyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With phosphorus pentachloride In 1,2-dichloro-ethane at 60 - 65℃; for 10h; Reagent/catalyst; Temperature; Solvent;94.9%
With phosphorus pentachloride In 1,2-dichloro-ethane at 60 - 65℃; for 10h; Reagent/catalyst; Temperature;94.9%
With trichlorophosphate In 1,2-dichloro-ethane; N,N-dimethyl-formamide Reflux;43g
2,3-Diaminopyridine
452-58-4

2,3-Diaminopyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With hydrogenchloride; copper dichloride; sodium nitrite In water at 20 - 45℃; for 5h; Reagent/catalyst; Large scale;89.5%
2-chloro-3-hydroxypyridine
6636-78-8

2-chloro-3-hydroxypyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With trichlorophosphate In N,N-dimethyl-formamide at 0 - 30℃; for 9h; Reagent/catalyst;88%
With chlorine In dichloromethane at 35 - 40℃; for 4h; Solvent; Temperature;126 g
With sulfolane; phosphorus pentachloride; trichlorophosphate at 150℃; for 6h; Reagent/catalyst;
pyridine hydrochloride
628-13-7

pyridine hydrochloride

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With pyridine; hydrogen In water at 40 - 60℃; under 2250.23 - 3750.38 Torr; Reagent/catalyst; Temperature; Pressure; Large scale;86.6%
With pyridine; hydrogen In water at 40 - 60℃; under 2250.23 - 3750.38 Torr; Temperature; Pressure; Reagent/catalyst; Large scale;86.6%
2-Chloro-3-nitropyridine
5470-18-8

2-Chloro-3-nitropyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With Dichlorophenylphosphine In various solvent(s) at 170℃; for 5h;81%
With sulfolane; phosphorus pentachloride; trichlorophosphate at 150℃; for 6h; Reagent/catalyst;
3-chloro-2-pyridinesulfonic acid

3-chloro-2-pyridinesulfonic acid

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
Stage #1: 3-chloro-2-pyridinesulfonic acid With hydrogenchloride; water In water at 103℃; for 5h;
Stage #2: With sodium chlorate for 5h; Temperature; Reflux;
80.3%
3-Chloropyridine
626-60-8

3-Chloropyridine

acetyl hypofluorite
78948-09-1

acetyl hypofluorite

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With dichloromethane80%
3-chloropyridine-2-carboxylic acid
57266-69-0

3-chloropyridine-2-carboxylic acid

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With tert-butylhypochlorite; dichloromethane; sodium hydrogencarbonate at 60℃; for 20h; Green chemistry;80%
With tert-butylhypochlorite; sodium carbonate; sodium chloride In dichloromethane at 30℃; for 20h; Schlenk technique;50%
2-Ethoxy-3-chloropyridine
177743-06-5

2-Ethoxy-3-chloropyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With N,N-dimethyl-formamide; trichlorophosphate at 95℃; for 12h;66%
2-Benzyloxy-3-chloro-pyridine

2-Benzyloxy-3-chloro-pyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With N,N-dimethyl-formamide; trichlorophosphate at 95℃; for 12h;66%
Pyridin-Palladium(II)-chlorid-Komplex

Pyridin-Palladium(II)-chlorid-Komplex

A

2-chloropyridine
109-09-1

2-chloropyridine

B

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

C

2,3,5-trichloropyridine
16063-70-0

2,3,5-trichloropyridine

Conditions
ConditionsYield
With chlorine In cyclohexane at 75℃; for 1h;A 9%
B 62%
C 4.5%
3-Chloropyridine
626-60-8

3-Chloropyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
Stage #1: 3-Chloropyridine With n-butyllithium In hexane at -60℃; for 1h;
Stage #2: With hexachloroethane In tetrahydrofuran; hexane at -60 - 20℃;
60%
Multi-step reaction with 3 steps
1: 3-chloro-benzenecarboperoxoic acid / chloroform / 20 °C
2: 30 h / Reflux
3: trichlorophosphate / 6 h / 100 °C
View Scheme
2-methoxy,3-chloropyridine
13472-84-9

2-methoxy,3-chloropyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With trichlorophosphate In N,N-dimethyl-formamide at 95℃; for 12h;59%
With N,N-dimethyl-formamide; trichlorophosphate at 95℃; for 12h;59%
5,6-dichloronicotinic acid
41667-95-2

5,6-dichloronicotinic acid

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
at 150℃; bei vorsichtiger Destillation unter vermindertem Druck;
3-chloropyridine-N-oxide
1851-22-5

3-chloropyridine-N-oxide

A

2,5 dichloropyridine
16110-09-1

2,5 dichloropyridine

B

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

C

3,4-dichloropyridine
55934-00-4

3,4-dichloropyridine

Conditions
ConditionsYield
With trichlorophosphate at 110℃; for 2h; Yield given. Yields of byproduct given;
2-Chloro-pyridine-3-diazonium; chloride
121983-37-7

2-Chloro-pyridine-3-diazonium; chloride

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With hydrogenchloride; copper(II) oxide In n-BuCl; water at 55 - 62℃; Product distribution / selectivity;
With hydrogenchloride; copper dichloride In n-Butyl chloride; water at 60℃; for 1.5h; Product distribution / selectivity;
2-chloro-3-aminopyridine
6298-19-7

2-chloro-3-aminopyridine

A

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

B

3,3'-dithiobis(2-chloropyridine)
69212-33-5

3,3'-dithiobis(2-chloropyridine)

C

2-chloro-3-pyridinesulfonyl chloride
6684-06-6

2-chloro-3-pyridinesulfonyl chloride

D

2-chloropyridine-3-sulfonic acid
6602-56-8

2-chloropyridine-3-sulfonic acid

E

3,3'-sulfonylbis(2-chloropyridine)

3,3'-sulfonylbis(2-chloropyridine)

Conditions
ConditionsYield
Stage #1: 2-chloro-3-aminopyridine With hydrogenchloride; acetic acid; sodium nitrite In water at 0℃; Sandmeyer reaction;
Stage #2: With sulfur dioxide; water; acetic acid; copper(l) chloride at 0℃; Sandmeyer reaction;
pyridin-3-ylamine
462-08-8

pyridin-3-ylamine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
Stage #1: pyridin-3-ylamine With hydrogenchloride; iron(III) chloride; chlorine; sodium nitrite In water at -8 - 20℃;
Stage #2: With hydrogenchloride; copper(l) chloride In water at 60 - 70℃;
Multi-step reaction with 2 steps
1: iron(III) chloride; hydrogenchloride; chlorine / water / 25 °C
2: iron(III) chloride; sodium nitrite / water / 30 °C
View Scheme
Stage #1: pyridin-3-ylamine With hydrogenchloride; dihydrogen peroxide In water at 5℃; for 2h;
Stage #2: With sodium nitrite In water at -5℃; for 0.416667h;
Stage #3: With copper(l) chloride In dichloromethane; water at 15 - 30℃; for 1.33333h;
Multi-step reaction with 2 steps
1: dihydrogen peroxide / 1 h / 5 - 15 °C
2: copper(l) chloride; sodium nitrite / water / 0.5 h / 33 - 38 °C
View Scheme
2-Chloronicotinoyl chloride
49609-84-9

2-Chloronicotinoyl chloride

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With oxalyl dichloride; palladium 10% on activated carbon In chlorobenzene at 380 - 395℃; for 1h; Time; Reagent/catalyst; Temperature; Solvent; Concentration; Inert atmosphere;43 %Spectr.
nicotinamide
98-92-0

nicotinamide

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium hydroxide; sodium hypochlorite / 2 h / 10 - 95 °C
2: iron(III) chloride; hydrogenchloride; chlorine / water / 25 °C
3: iron(III) chloride; sodium nitrite / water / 30 °C
View Scheme
Multi-step reaction with 3 steps
1: sodium hypochlorite / water / 2.5 h / 0 - 100 °C
2: dihydrogen peroxide / 1 h / 5 - 15 °C
3: copper(l) chloride; sodium nitrite / water / 0.5 h / 33 - 38 °C
View Scheme
2-acetyloxy-3-chloropyridine
98273-80-4

2-acetyloxy-3-chloropyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With trichlorophosphate at 100℃; for 6h; Reagent/catalyst;
2,3,6-trichloropyridine
6515-09-9

2,3,6-trichloropyridine

A

3-Chloropyridine
626-60-8

3-Chloropyridine

B

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; hydrogen; triethylamine In isopropyl alcohol at 85℃; under 3750.38 Torr; for 3h;
2,3,6-trichloropyridine
6515-09-9

2,3,6-trichloropyridine

A

2-chloropyridine
109-09-1

2-chloropyridine

B

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
With Wilkinson's catalyst; hydrogen; triethylamine In isopropyl alcohol at 85℃; under 3750.38 Torr; for 1h;
pyridine
110-86-1

pyridine

A

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

B

2,3,5-trichloropyridine
16063-70-0

2,3,5-trichloropyridine

Conditions
ConditionsYield
Stage #1: pyridine With iron(III) chloride; chlorine In tetrachloromethane Large scale;
Stage #2: With palladium on activated charcoal In tetrachloromethane; ethanol at 80℃; under 750.075 Torr; Reagent/catalyst; Solvent; Pressure; Temperature; Large scale;
A 8 kg
B 1840.8 kg
3-pyridyl acetate
17747-43-2

3-pyridyl acetate

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: chlorine / dichloromethane; water / 4 h / 20 - 30 °C
2: water / dichloromethane / 2 h / 35 - 40 °C
3: chlorine / dichloromethane / 4 h / 35 - 40 °C
View Scheme
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

bis(triphenylphosphine)nickel(II) chloride
14264-16-5, 53996-95-5, 62075-39-2, 39716-73-9

bis(triphenylphosphine)nickel(II) chloride

[NiCl(ClC5H3N)(P(C6H5)3)]2
680973-41-5

[NiCl(ClC5H3N)(P(C6H5)3)]2

Conditions
ConditionsYield
With Zn; azabis(isobutyronitrile) In tetrahydrofuran (Ar); stirring (25°C, 1 h); solvent removal, extracting (CH2Cl2), filtn., solvent removal, stirring (Et2O), filtn., recrystallization (CH2Cl2); elem. anal.;99%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

pyrrole
109-97-7

pyrrole

3-chloro-2-(1H-pyrrol-1-yl)pyridine
914457-19-5

3-chloro-2-(1H-pyrrol-1-yl)pyridine

Conditions
ConditionsYield
Stage #1: pyrrole With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 0.5h;
Stage #2: 2,3-dichloro-pyridine In N,N-dimethyl-formamide at 80℃; for 3h;
99%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

(3-chloro-2-pyridyl)hydrazine
22841-92-5

(3-chloro-2-pyridyl)hydrazine

Conditions
ConditionsYield
With N-Methyldiethanolamine; hydrazine hydrate at 102 - 105℃; under 2250.23 - 3000.3 Torr; for 8h; Inert atmosphere; Autoclave; Large scale;98.12%
With hydrazine hydrate In ethanol for 25h; Reflux;97.6%
With hydrazine hydrate In ethanol for 25h; Reflux;96%
benzoxazole
273-53-0

benzoxazole

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

2-(2-chloropyridin-3-yl)benzo[d]oxazole

2-(2-chloropyridin-3-yl)benzo[d]oxazole

Conditions
ConditionsYield
With copper(l) iodide; potassium phosphate tribasic heptahydrate; palladium diacetate; nixantphos In N,N-dimethyl-formamide at 120℃; for 12h; Inert atmosphere;98%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

tri(p-tolyl)bismuth
5142-75-6

tri(p-tolyl)bismuth

3-chloro-2-(4-methylphenyl)pyridine
892482-36-9

3-chloro-2-(4-methylphenyl)pyridine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In N,N-dimethyl acetamide at 90℃; for 4h; Inert atmosphere; Schlenk technique; regioselective reaction;97%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

2,3-dichloropyridine 1-oxide
53976-65-1

2,3-dichloropyridine 1-oxide

Conditions
ConditionsYield
With trifluoromethylsulfonic anhydride; urea hydrogen peroxide adduct In dichloromethane at 10 - 20℃;96%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0 - 30℃; for 32h; Inert atmosphere;74%
With dihydrogen peroxide; acetic anhydride 1.)r.t., 5 h 2.)60-65 deg C, 30 h;
With urea hydrogen peroxide adduct; trifluoroacetic anhydride In dichloromethane at 0 - 20℃;11 g
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

carbon dioxide
124-38-9

carbon dioxide

2,3-dichloroisonicotinic acid
184416-84-0

2,3-dichloroisonicotinic acid

Conditions
ConditionsYield
Stage #1: 2,3-dichloro-pyridine With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -75℃; for 2h;
Stage #2: carbon dioxide at -78℃;
96%
Stage #1: 2,3-dichloro-pyridine With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -78 - -25℃; for 3h;
Stage #2: carbon dioxide In tetrahydrofuran; hexane at 20℃; for 18h;
Stage #3: With hydrogenchloride; water In tetrahydrofuran; diethyl ether; hexane at 0 - 20℃;
80%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

2,2,3,3-tetrafluoropropanol
76-37-9

2,2,3,3-tetrafluoropropanol

3-chloro-2-(2,2,3,3-tetrafluoropropyl)pyridine
1355067-32-1

3-chloro-2-(2,2,3,3-tetrafluoropropyl)pyridine

Conditions
ConditionsYield
Stage #1: 2,2,3,3-tetrafluoropropanol With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 1h;
Stage #2: 2,3-dichloro-pyridine In tetrahydrofuran; mineral oil for 16h; Reflux;
96%
Stage #1: 2,2,3,3-tetrafluoropropanol With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 1h;
Stage #2: 2,3-dichloro-pyridine In tetrahydrofuran; mineral oil for 16h; Reflux;
96%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

2-(prop-2-yloxycarbonyl)-5-trfluoromethylphenylboronic acid
444993-18-4

2-(prop-2-yloxycarbonyl)-5-trfluoromethylphenylboronic acid

lithium hydroxide
1310-65-2

lithium hydroxide

2-(3-chloro-pyridin-2-yl)-4-trifluoromethyl-benzoic acid
1423022-47-2

2-(3-chloro-pyridin-2-yl)-4-trifluoromethyl-benzoic acid

Conditions
ConditionsYield
Stage #1: 2,3-dichloro-pyridine; 2-(prop-2-yloxycarbonyl)-5-trfluoromethylphenylboronic acid With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,4-dioxane; water at 30 - 110℃; for 20h; Inert atmosphere;
Stage #2: lithium hydroxide In 1,4-dioxane; water at 70℃;
96%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

3-bromo-4,5-dihydro-1H-pyrazole-5-carboxylic acid ethyl ester

3-bromo-4,5-dihydro-1H-pyrazole-5-carboxylic acid ethyl ester

5-bromo-2-(3-chloro-pyridin-2-yl)-3,4-dihydro-2H-pyrazole-3-carboxylic acid ethyl ester
500011-91-6

5-bromo-2-(3-chloro-pyridin-2-yl)-3,4-dihydro-2H-pyrazole-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
With sodium ethanolate In ethanol at 83℃; for 3h;94.9%
piperazine
110-85-0

piperazine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

1-(3-chloro-2-pyridyl)piperazine
87394-55-6

1-(3-chloro-2-pyridyl)piperazine

Conditions
ConditionsYield
In butan-1-ol for 3h; Reflux;94%
In butan-1-ol for 18h; Reflux;92%
In ethanol 1.) ice bath, 2.) room temperature;90.8%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

2-(adamantan-1-yloxy)ethan-1-amine
25225-13-2

2-(adamantan-1-yloxy)ethan-1-amine

N-[2-(1-adamantyloxy)ethyl]-3-chloropyridin-2-amine

N-[2-(1-adamantyloxy)ethyl]-3-chloropyridin-2-amine

Conditions
ConditionsYield
With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; bis(dibenzylideneacetone)-palladium(0); sodium t-butanolate In 1,4-dioxane Reagent/catalyst; Solvent; Temperature; Inert atmosphere; Reflux;94%
2-aminopyridine
504-29-0

2-aminopyridine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

3-chloro-N-(pyridin-2-yl)pyridin-2-amine
138144-95-3

3-chloro-N-(pyridin-2-yl)pyridin-2-amine

Conditions
ConditionsYield
With potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate In toluene for 18h; Heating;93%
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 180℃; for 0.5h; Buchwald-Hartwig amination; Inert atmosphere; Microwave irradiation; regioselective reaction;81%
With palladium diacetate; triphenylphosphine; sodium t-butanolate In toluene at 120℃; for 17h; Inert atmosphere;61.7%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

4-methoxy-aniline
104-94-9

4-methoxy-aniline

3-chloro-N-(4-methoxyphenyl)pyridin-2-amine
370571-31-6

3-chloro-N-(4-methoxyphenyl)pyridin-2-amine

Conditions
ConditionsYield
With potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate In toluene for 18h; Heating;93%
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene for 18h; Buchwald-Hartwig reaction; Reflux; regioselective reaction;93%
Stage #1: 2,3-dichloro-pyridine With palladium diacetate; triphenylphosphine; sodium t-butanolate In toluene under 20 Torr; for 0.166667h; Buchwald-Hartwig Coupling; Inert atmosphere;
Stage #2: 4-methoxy-aniline In toluene at 100℃; for 16h; Buchwald-Hartwig Coupling; Inert atmosphere;
91%
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 180℃; for 0.5h; Buchwald-Hartwig amination; Inert atmosphere; Microwave irradiation; regioselective reaction;82%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

C13H13ClN2O2
1146547-65-0

C13H13ClN2O2

Conditions
ConditionsYield
Stage #1: 2,3-dichloro-pyridine With palladium diacetate; triphenylphosphine; sodium t-butanolate In toluene under 20 Torr; for 0.166667h; Buchwald-Hartwig Coupling; Inert atmosphere;
Stage #2: 3.5-dimethoxyaniline In toluene at 100℃; for 16h; Buchwald-Hartwig Coupling; Inert atmosphere;
93%
Stage #1: 2,3-dichloro-pyridine; 3.5-dimethoxyaniline With palladium diacetate; triphenylphosphine; sodium t-butanolate In o-xylene at 120℃; for 3h; Inert atmosphere;
Stage #2: With palladium diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; tricyclohexylphosphine tetrafluoroborate In N,N-dimethyl acetamide; o-xylene at 145℃; for 16h; Inert atmosphere;
66%
With palladium diacetate; triphenylphosphine; sodium t-butanolate Inert atmosphere; Heating;
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

sodium 4-methylbenzenesulfinate
824-79-3

sodium 4-methylbenzenesulfinate

3-chloro-2-(toluene-4-sulfonyl)-pyridine
1258786-39-8

3-chloro-2-(toluene-4-sulfonyl)-pyridine

Conditions
ConditionsYield
With hydrogenchloride; tetrabutyl-ammonium chloride In N,N-dimethyl acetamide; water at 100℃; for 24h;93%
4-HYDROXYPIPERIDINE
5382-16-1

4-HYDROXYPIPERIDINE

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

1-(3-chloropyridin-2-yl)piperidin-4-ol
1250282-78-0

1-(3-chloropyridin-2-yl)piperidin-4-ol

Conditions
ConditionsYield
In dimethyl sulfoxide at 120℃;93%
In N,N-dimethyl-formamide at 80 - 90℃; for 3h;1.76 g
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

3-bromo-4,5-dihydro-1H-pyrazole-5-carboxylic acid methyl ester

3-bromo-4,5-dihydro-1H-pyrazole-5-carboxylic acid methyl ester

3-bromo-1-(3-chloro-2-pyridyl)-4,5-dihydro-1H-pyrazole-5-carboxylic acid methyl ester

3-bromo-1-(3-chloro-2-pyridyl)-4,5-dihydro-1H-pyrazole-5-carboxylic acid methyl ester

Conditions
ConditionsYield
With sodium methylate In methanol at 80℃; for 3h;92.7%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

4,4-ethylenedioxy-piperidine
177-11-7

4,4-ethylenedioxy-piperidine

C12H15ClN2O2
828265-97-0

C12H15ClN2O2

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 150℃; for 16h;92.5%
With triethylamine In ethanol at 160℃;
With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 125℃; for 12h;
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

tris(4-methoxyphenyl)bismuth
33397-21-6

tris(4-methoxyphenyl)bismuth

3-chloro-2-(4-methoxyphenyl)pyridine

3-chloro-2-(4-methoxyphenyl)pyridine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In N,N-dimethyl acetamide at 90℃; for 4h; Inert atmosphere; Schlenk technique; regioselective reaction;92%
2-Aminopyrazine
5049-61-6

2-Aminopyrazine

2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

(2-pyrazyl)(3-chloro-2-pyridyl)amine

(2-pyrazyl)(3-chloro-2-pyridyl)amine

Conditions
ConditionsYield
With potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate In toluene for 18h; Heating;91%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

2-methoxy-phenylamine
90-04-0

2-methoxy-phenylamine

3-chloro-N-(2-methoxyphenyl)pyridin-2-amine
1005499-19-3

3-chloro-N-(2-methoxyphenyl)pyridin-2-amine

Conditions
ConditionsYield
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene for 18h; Buchwald-Hartwig reaction; Reflux; regioselective reaction;91%
Stage #1: 2,3-dichloro-pyridine With palladium diacetate; triphenylphosphine; sodium t-butanolate In toluene under 20 Torr; for 0.166667h; Buchwald-Hartwig Coupling; Inert atmosphere;
Stage #2: 2-methoxy-phenylamine In toluene at 100℃; for 16h; Buchwald-Hartwig Coupling; Inert atmosphere;
82%
With potassium carbonate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 120℃; for 2h;81%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

benzylamine
100-46-9

benzylamine

N-benzyl-3-chloro-2-pyridinamine
1042512-03-7

N-benzyl-3-chloro-2-pyridinamine

Conditions
ConditionsYield
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 130℃; for 16h; Inert atmosphere;91%
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 130℃; for 16h; Buchwald-Hartwig Coupling; Inert atmosphere;91%
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 130℃; for 16h; Inert atmosphere;91%
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 130℃; for 16h; Inert atmosphere;90%
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 180℃; for 0.5h; Buchwald-Hartwig amination; Inert atmosphere; Microwave irradiation; regioselective reaction;52%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

4-tert-butylphenylboronic acid
123324-71-0

4-tert-butylphenylboronic acid

C15H16ClN

C15H16ClN

Conditions
ConditionsYield
With palladium diacetate; potassium carbonate; nixantphos In tetrahydrofuran; water at 20℃; for 6h; Suzuki-Miyaura Coupling;91%
2,3-dichloro-pyridine
2402-77-9

2,3-dichloro-pyridine

benzyl(bromo)zinc
62673-31-8

benzyl(bromo)zinc

2-benzyl-3-chloropyridine

2-benzyl-3-chloropyridine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 70℃; for 18h; Inert atmosphere;91%
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