Factory direct sales, accept customization. 2,3-Dichloropyridine is used as a reagent for the preparation of substituted 3-(5-membered heterocycle-carboxamido)pyridine derivatives for treatment of autoimmune and inflammatory diseases. Also in the sy
Cas:2402-77-9
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inquiryItems Standard Result Appearance White to off-white solid Off-White Solid Melting point 65.0℃. -6
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inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White to light yellow solid Storage:Store at RT. Package:1kg/
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inquiryhigh quality Appearance:solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:OLED Intermediate Transportation:by air or by sea Port:shanghai
2,3-Dichloropyridine Cas No.:2402-77-9 Molecular Structure: 1. Product Name: 2,3-Dichloropyridine, 99% min. 2. Cas No.: 2402-77-9 3. EINECS No.: 219-281-8 4. Molecular Formula: C5H3Cl2N 5. M.W: 147.99 6. Properties:
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiryHebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car
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inquiryTIANFUCHEM--2402-77-9--2,3-Dichloropyridine in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business relati
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inquiryProduct Description Product website: http://www.finerchem.com/pro01en/id/1649.html Product Name 2,3-Dichloropyridine CAS No. 2402-77-9
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inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryProduct: 2,3-Dichloropyridine Content: ≥99% CAS No: 2402-77-9 Melting point 64-
Cas:2402-77-9
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inquiryAppearance:White powder Storage:R.T Package:25kg/drum Application:Pesticide/Pharmaceutical Intermediate Transportation:Express/Sea/Air Port:Any port in China
Cas:2402-77-9
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inquiryAdvantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best serv
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inquiryAbout us Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad.
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inquiryC5H3Cl2N Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, steroids, pharma
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
2,3,4,6-Tetrachloropyridine
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
With hydrogen; triethylamine; urea; citric acid In ethyl acetate at 50℃; under 7500.75 Torr; for 7h; Solvent; Temperature; Pressure; Reagent/catalyst; Autoclave; | 98.1% |
Conditions | Yield |
---|---|
With carbonylhydridetris(triphenylphosphine)rhodium(I); hydrogen; triethylamine In methanol at 60℃; under 450045 Torr; Temperature; Solvent; Pressure; Autoclave; | 98% |
With methanol; palladium 10% on activated carbon; 3-p-menthene at 60℃; for 4h; Temperature; Reagent/catalyst; | 95% |
With hydrogen In methanol at 75℃; under 750.075 Torr; for 8h; Reagent/catalyst; Autoclave; | 95.3% |
Conditions | Yield |
---|---|
In dimethyl sulfoxide | A 96.3% B n/a |
Conditions | Yield |
---|---|
Stage #1: 2-chloro-3-aminopyridine With hydrogenchloride; sodium nitrite In water at 5 - 15℃; for 0.75h; Stage #2: With hydrogenchloride; aminosulfonic acid; copper(II) chloride dihydrate In water at 55 - 62℃; Product distribution / selectivity; | 95% |
With hydrogenchloride; thionyl chloride; nitric acid In water at 0 - 5℃; | 91% |
With hydrogenchloride; sodium nitrite In water at -5 - 40℃; for 1h; Sandmeyer Reaction; Cooling with ice; Inert atmosphere; | 83% |
2-hydroxy-3-chloropyridine
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
With phosphorus pentachloride In 1,2-dichloro-ethane at 60 - 65℃; for 10h; Reagent/catalyst; Temperature; Solvent; | 94.9% |
With phosphorus pentachloride In 1,2-dichloro-ethane at 60 - 65℃; for 10h; Reagent/catalyst; Temperature; | 94.9% |
With trichlorophosphate In 1,2-dichloro-ethane; N,N-dimethyl-formamide Reflux; | 43g |
Conditions | Yield |
---|---|
With hydrogenchloride; copper dichloride; sodium nitrite In water at 20 - 45℃; for 5h; Reagent/catalyst; Large scale; | 89.5% |
Conditions | Yield |
---|---|
With trichlorophosphate In N,N-dimethyl-formamide at 0 - 30℃; for 9h; Reagent/catalyst; | 88% |
With chlorine In dichloromethane at 35 - 40℃; for 4h; Solvent; Temperature; | 126 g |
With sulfolane; phosphorus pentachloride; trichlorophosphate at 150℃; for 6h; Reagent/catalyst; |
Conditions | Yield |
---|---|
With pyridine; hydrogen In water at 40 - 60℃; under 2250.23 - 3750.38 Torr; Reagent/catalyst; Temperature; Pressure; Large scale; | 86.6% |
With pyridine; hydrogen In water at 40 - 60℃; under 2250.23 - 3750.38 Torr; Temperature; Pressure; Reagent/catalyst; Large scale; | 86.6% |
Conditions | Yield |
---|---|
With Dichlorophenylphosphine In various solvent(s) at 170℃; for 5h; | 81% |
With sulfolane; phosphorus pentachloride; trichlorophosphate at 150℃; for 6h; Reagent/catalyst; |
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
Stage #1: 3-chloro-2-pyridinesulfonic acid With hydrogenchloride; water In water at 103℃; for 5h; Stage #2: With sodium chlorate for 5h; Temperature; Reflux; | 80.3% |
Conditions | Yield |
---|---|
With dichloromethane | 80% |
3-chloropyridine-2-carboxylic acid
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
With tert-butylhypochlorite; dichloromethane; sodium hydrogencarbonate at 60℃; for 20h; Green chemistry; | 80% |
With tert-butylhypochlorite; sodium carbonate; sodium chloride In dichloromethane at 30℃; for 20h; Schlenk technique; | 50% |
2-Ethoxy-3-chloropyridine
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
With N,N-dimethyl-formamide; trichlorophosphate at 95℃; for 12h; | 66% |
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
With N,N-dimethyl-formamide; trichlorophosphate at 95℃; for 12h; | 66% |
Conditions | Yield |
---|---|
With chlorine In cyclohexane at 75℃; for 1h; | A 9% B 62% C 4.5% |
Conditions | Yield |
---|---|
Stage #1: 3-Chloropyridine With n-butyllithium In hexane at -60℃; for 1h; Stage #2: With hexachloroethane In tetrahydrofuran; hexane at -60 - 20℃; | 60% |
Multi-step reaction with 3 steps 1: 3-chloro-benzenecarboperoxoic acid / chloroform / 20 °C 2: 30 h / Reflux 3: trichlorophosphate / 6 h / 100 °C View Scheme |
2-methoxy,3-chloropyridine
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
With trichlorophosphate In N,N-dimethyl-formamide at 95℃; for 12h; | 59% |
With N,N-dimethyl-formamide; trichlorophosphate at 95℃; for 12h; | 59% |
5,6-dichloronicotinic acid
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
at 150℃; bei vorsichtiger Destillation unter vermindertem Druck; |
3-chloropyridine-N-oxide
A
2,5 dichloropyridine
B
2,3-dichloro-pyridine
C
3,4-dichloropyridine
Conditions | Yield |
---|---|
With trichlorophosphate at 110℃; for 2h; Yield given. Yields of byproduct given; |
2-Chloro-pyridine-3-diazonium; chloride
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
With hydrogenchloride; copper(II) oxide In n-BuCl; water at 55 - 62℃; Product distribution / selectivity; | |
With hydrogenchloride; copper dichloride In n-Butyl chloride; water at 60℃; for 1.5h; Product distribution / selectivity; |
2-chloro-3-aminopyridine
A
2,3-dichloro-pyridine
B
3,3'-dithiobis(2-chloropyridine)
C
2-chloro-3-pyridinesulfonyl chloride
D
2-chloropyridine-3-sulfonic acid
Conditions | Yield |
---|---|
Stage #1: 2-chloro-3-aminopyridine With hydrogenchloride; acetic acid; sodium nitrite In water at 0℃; Sandmeyer reaction; Stage #2: With sulfur dioxide; water; acetic acid; copper(l) chloride at 0℃; Sandmeyer reaction; |
Conditions | Yield |
---|---|
Stage #1: pyridin-3-ylamine With hydrogenchloride; iron(III) chloride; chlorine; sodium nitrite In water at -8 - 20℃; Stage #2: With hydrogenchloride; copper(l) chloride In water at 60 - 70℃; | |
Multi-step reaction with 2 steps 1: iron(III) chloride; hydrogenchloride; chlorine / water / 25 °C 2: iron(III) chloride; sodium nitrite / water / 30 °C View Scheme | |
Stage #1: pyridin-3-ylamine With hydrogenchloride; dihydrogen peroxide In water at 5℃; for 2h; Stage #2: With sodium nitrite In water at -5℃; for 0.416667h; Stage #3: With copper(l) chloride In dichloromethane; water at 15 - 30℃; for 1.33333h; | |
Multi-step reaction with 2 steps 1: dihydrogen peroxide / 1 h / 5 - 15 °C 2: copper(l) chloride; sodium nitrite / water / 0.5 h / 33 - 38 °C View Scheme |
2-Chloronicotinoyl chloride
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
With oxalyl dichloride; palladium 10% on activated carbon In chlorobenzene at 380 - 395℃; for 1h; Time; Reagent/catalyst; Temperature; Solvent; Concentration; Inert atmosphere; | 43 %Spectr. |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: sodium hydroxide; sodium hypochlorite / 2 h / 10 - 95 °C 2: iron(III) chloride; hydrogenchloride; chlorine / water / 25 °C 3: iron(III) chloride; sodium nitrite / water / 30 °C View Scheme | |
Multi-step reaction with 3 steps 1: sodium hypochlorite / water / 2.5 h / 0 - 100 °C 2: dihydrogen peroxide / 1 h / 5 - 15 °C 3: copper(l) chloride; sodium nitrite / water / 0.5 h / 33 - 38 °C View Scheme |
2-acetyloxy-3-chloropyridine
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
With trichlorophosphate at 100℃; for 6h; Reagent/catalyst; |
Conditions | Yield |
---|---|
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; hydrogen; triethylamine In isopropyl alcohol at 85℃; under 3750.38 Torr; for 3h; |
Conditions | Yield |
---|---|
With Wilkinson's catalyst; hydrogen; triethylamine In isopropyl alcohol at 85℃; under 3750.38 Torr; for 1h; |
Conditions | Yield |
---|---|
Stage #1: pyridine With iron(III) chloride; chlorine In tetrachloromethane Large scale; Stage #2: With palladium on activated charcoal In tetrachloromethane; ethanol at 80℃; under 750.075 Torr; Reagent/catalyst; Solvent; Pressure; Temperature; Large scale; | A 8 kg B 1840.8 kg |
3-pyridyl acetate
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: chlorine / dichloromethane; water / 4 h / 20 - 30 °C 2: water / dichloromethane / 2 h / 35 - 40 °C 3: chlorine / dichloromethane / 4 h / 35 - 40 °C View Scheme |
2,3-dichloro-pyridine
bis(triphenylphosphine)nickel(II) chloride
[NiCl(ClC5H3N)(P(C6H5)3)]2
Conditions | Yield |
---|---|
With Zn; azabis(isobutyronitrile) In tetrahydrofuran (Ar); stirring (25°C, 1 h); solvent removal, extracting (CH2Cl2), filtn., solvent removal, stirring (Et2O), filtn., recrystallization (CH2Cl2); elem. anal.; | 99% |
Conditions | Yield |
---|---|
Stage #1: pyrrole With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 0.5h; Stage #2: 2,3-dichloro-pyridine In N,N-dimethyl-formamide at 80℃; for 3h; | 99% |
2,3-dichloro-pyridine
(3-chloro-2-pyridyl)hydrazine
Conditions | Yield |
---|---|
With N-Methyldiethanolamine; hydrazine hydrate at 102 - 105℃; under 2250.23 - 3000.3 Torr; for 8h; Inert atmosphere; Autoclave; Large scale; | 98.12% |
With hydrazine hydrate In ethanol for 25h; Reflux; | 97.6% |
With hydrazine hydrate In ethanol for 25h; Reflux; | 96% |
Conditions | Yield |
---|---|
With copper(l) iodide; potassium phosphate tribasic heptahydrate; palladium diacetate; nixantphos In N,N-dimethyl-formamide at 120℃; for 12h; Inert atmosphere; | 98% |
2,3-dichloro-pyridine
tri(p-tolyl)bismuth
3-chloro-2-(4-methylphenyl)pyridine
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In N,N-dimethyl acetamide at 90℃; for 4h; Inert atmosphere; Schlenk technique; regioselective reaction; | 97% |
2,3-dichloro-pyridine
2,3-dichloropyridine 1-oxide
Conditions | Yield |
---|---|
With trifluoromethylsulfonic anhydride; urea hydrogen peroxide adduct In dichloromethane at 10 - 20℃; | 96% |
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0 - 30℃; for 32h; Inert atmosphere; | 74% |
With dihydrogen peroxide; acetic anhydride 1.)r.t., 5 h 2.)60-65 deg C, 30 h; | |
With urea hydrogen peroxide adduct; trifluoroacetic anhydride In dichloromethane at 0 - 20℃; | 11 g |
Conditions | Yield |
---|---|
Stage #1: 2,3-dichloro-pyridine With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -75℃; for 2h; Stage #2: carbon dioxide at -78℃; | 96% |
Stage #1: 2,3-dichloro-pyridine With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -78 - -25℃; for 3h; Stage #2: carbon dioxide In tetrahydrofuran; hexane at 20℃; for 18h; Stage #3: With hydrogenchloride; water In tetrahydrofuran; diethyl ether; hexane at 0 - 20℃; | 80% |
2,3-dichloro-pyridine
2,2,3,3-tetrafluoropropanol
3-chloro-2-(2,2,3,3-tetrafluoropropyl)pyridine
Conditions | Yield |
---|---|
Stage #1: 2,2,3,3-tetrafluoropropanol With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 1h; Stage #2: 2,3-dichloro-pyridine In tetrahydrofuran; mineral oil for 16h; Reflux; | 96% |
Stage #1: 2,2,3,3-tetrafluoropropanol With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 1h; Stage #2: 2,3-dichloro-pyridine In tetrahydrofuran; mineral oil for 16h; Reflux; | 96% |
2,3-dichloro-pyridine
2-(prop-2-yloxycarbonyl)-5-trfluoromethylphenylboronic acid
lithium hydroxide
2-(3-chloro-pyridin-2-yl)-4-trifluoromethyl-benzoic acid
Conditions | Yield |
---|---|
Stage #1: 2,3-dichloro-pyridine; 2-(prop-2-yloxycarbonyl)-5-trfluoromethylphenylboronic acid With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,4-dioxane; water at 30 - 110℃; for 20h; Inert atmosphere; Stage #2: lithium hydroxide In 1,4-dioxane; water at 70℃; | 96% |
2,3-dichloro-pyridine
5-bromo-2-(3-chloro-pyridin-2-yl)-3,4-dihydro-2H-pyrazole-3-carboxylic acid ethyl ester
Conditions | Yield |
---|---|
With sodium ethanolate In ethanol at 83℃; for 3h; | 94.9% |
Conditions | Yield |
---|---|
In butan-1-ol for 3h; Reflux; | 94% |
In butan-1-ol for 18h; Reflux; | 92% |
In ethanol 1.) ice bath, 2.) room temperature; | 90.8% |
2,3-dichloro-pyridine
2-(adamantan-1-yloxy)ethan-1-amine
Conditions | Yield |
---|---|
With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; bis(dibenzylideneacetone)-palladium(0); sodium t-butanolate In 1,4-dioxane Reagent/catalyst; Solvent; Temperature; Inert atmosphere; Reflux; | 94% |
2-aminopyridine
2,3-dichloro-pyridine
3-chloro-N-(pyridin-2-yl)pyridin-2-amine
Conditions | Yield |
---|---|
With potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate In toluene for 18h; Heating; | 93% |
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 180℃; for 0.5h; Buchwald-Hartwig amination; Inert atmosphere; Microwave irradiation; regioselective reaction; | 81% |
With palladium diacetate; triphenylphosphine; sodium t-butanolate In toluene at 120℃; for 17h; Inert atmosphere; | 61.7% |
2,3-dichloro-pyridine
4-methoxy-aniline
3-chloro-N-(4-methoxyphenyl)pyridin-2-amine
Conditions | Yield |
---|---|
With potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate In toluene for 18h; Heating; | 93% |
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene for 18h; Buchwald-Hartwig reaction; Reflux; regioselective reaction; | 93% |
Stage #1: 2,3-dichloro-pyridine With palladium diacetate; triphenylphosphine; sodium t-butanolate In toluene under 20 Torr; for 0.166667h; Buchwald-Hartwig Coupling; Inert atmosphere; Stage #2: 4-methoxy-aniline In toluene at 100℃; for 16h; Buchwald-Hartwig Coupling; Inert atmosphere; | 91% |
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 180℃; for 0.5h; Buchwald-Hartwig amination; Inert atmosphere; Microwave irradiation; regioselective reaction; | 82% |
Conditions | Yield |
---|---|
Stage #1: 2,3-dichloro-pyridine With palladium diacetate; triphenylphosphine; sodium t-butanolate In toluene under 20 Torr; for 0.166667h; Buchwald-Hartwig Coupling; Inert atmosphere; Stage #2: 3.5-dimethoxyaniline In toluene at 100℃; for 16h; Buchwald-Hartwig Coupling; Inert atmosphere; | 93% |
Stage #1: 2,3-dichloro-pyridine; 3.5-dimethoxyaniline With palladium diacetate; triphenylphosphine; sodium t-butanolate In o-xylene at 120℃; for 3h; Inert atmosphere; Stage #2: With palladium diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; tricyclohexylphosphine tetrafluoroborate In N,N-dimethyl acetamide; o-xylene at 145℃; for 16h; Inert atmosphere; | 66% |
With palladium diacetate; triphenylphosphine; sodium t-butanolate Inert atmosphere; Heating; |
2,3-dichloro-pyridine
sodium 4-methylbenzenesulfinate
3-chloro-2-(toluene-4-sulfonyl)-pyridine
Conditions | Yield |
---|---|
With hydrogenchloride; tetrabutyl-ammonium chloride In N,N-dimethyl acetamide; water at 100℃; for 24h; | 93% |
4-HYDROXYPIPERIDINE
2,3-dichloro-pyridine
1-(3-chloropyridin-2-yl)piperidin-4-ol
Conditions | Yield |
---|---|
In dimethyl sulfoxide at 120℃; | 93% |
In N,N-dimethyl-formamide at 80 - 90℃; for 3h; | 1.76 g |
2,3-dichloro-pyridine
Conditions | Yield |
---|---|
With sodium methylate In methanol at 80℃; for 3h; | 92.7% |
Conditions | Yield |
---|---|
With potassium carbonate In dimethyl sulfoxide at 150℃; for 16h; | 92.5% |
With triethylamine In ethanol at 160℃; | |
With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 125℃; for 12h; |
2,3-dichloro-pyridine
tris(4-methoxyphenyl)bismuth
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In N,N-dimethyl acetamide at 90℃; for 4h; Inert atmosphere; Schlenk technique; regioselective reaction; | 92% |
Conditions | Yield |
---|---|
With potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate In toluene for 18h; Heating; | 91% |
2,3-dichloro-pyridine
2-methoxy-phenylamine
3-chloro-N-(2-methoxyphenyl)pyridin-2-amine
Conditions | Yield |
---|---|
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene for 18h; Buchwald-Hartwig reaction; Reflux; regioselective reaction; | 91% |
Stage #1: 2,3-dichloro-pyridine With palladium diacetate; triphenylphosphine; sodium t-butanolate In toluene under 20 Torr; for 0.166667h; Buchwald-Hartwig Coupling; Inert atmosphere; Stage #2: 2-methoxy-phenylamine In toluene at 100℃; for 16h; Buchwald-Hartwig Coupling; Inert atmosphere; | 82% |
With potassium carbonate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 120℃; for 2h; | 81% |
Conditions | Yield |
---|---|
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 130℃; for 16h; Inert atmosphere; | 91% |
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 130℃; for 16h; Buchwald-Hartwig Coupling; Inert atmosphere; | 91% |
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 130℃; for 16h; Inert atmosphere; | 91% |
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 130℃; for 16h; Inert atmosphere; | 90% |
With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 180℃; for 0.5h; Buchwald-Hartwig amination; Inert atmosphere; Microwave irradiation; regioselective reaction; | 52% |
Conditions | Yield |
---|---|
With palladium diacetate; potassium carbonate; nixantphos In tetrahydrofuran; water at 20℃; for 6h; Suzuki-Miyaura Coupling; | 91% |
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 70℃; for 18h; Inert atmosphere; | 91% |
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