As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryHebei yanxi chemical co., LTD is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carb
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inquiryProduct description: Product name 2,6-Dichloropyridine CAS number 2402-78-0 Assay ≥99% Appearance White powder Capacity 200mt/year Application Pharmaceutical/pesticide interm
Cas:2402-78-0
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inquiryCAS No.: 2402-78-0 Other Names: 2,6-Dichloropyridinr MF: C5H3Cl2N EINECS No.: 219-282-3 Place of Origin: Anhui,
Cas:2402-78-0
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
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inquiryCangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi
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inquiryProduct Name: 2,6-Dichloropyridine Synonyms: 2,6-Dichloropyridinr;2,6-Dichloropyridine ,98%;2,6-Dichloropyridine, 98% 100GR;2,6- twochlorine pyridine;2,6-DichL;oropyridine;AKOS BBS-00004314;26DCLPY CAS: 2402-78-0 MF: C5H3Cl2N MW: 147.99 EINECS
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inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryName 2,6-Dichloropyridine Synonyms EINECS 219-282-3;Pyridine, 2,6-dichloro-;2,6-Dichlor-pyridin;2,6-Cl2C5H3N;Pyridine,2,6-dichloro;2,5-DICHLOROANILINE;2,6-dichloro-pyrid
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inquiryAppearance:White or off-white crystal Storage:R.T Package:125kg/200kg/Barrel Application:Pharmaceutical and organic synthesis intermediates. Transportation:Express/Sea/Air Port:Any port in China
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inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
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inquiryPacking: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Appearance:White crystal powder / Refer to COA Storage:Ref
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inquiry2,6-Dichloropyridine CAS:2402-78-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inter
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Product quality: Our company have high quality product , and also the product we have good manufacture . First of all, this product is of fine quality. Every finish should be checked by quality inspection system.And every one should be also tried
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inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Appearance:white powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:pharmaceutical intermediate,Fine chemi.. Transportation:Common products:Sea/Air/Courier Da
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inquiry1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie
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inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
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inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:2402-78-0
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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Cas:2402-78-0
Min.Order:100 Gram
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Type:Other
inquiryConditions | Yield |
---|---|
With chlorine at 100 - 150℃; Temperature; UV-irradiation; Large scale; | 94.05% |
Stage #1: 2-chloropyridine With n-butyllithium; BuLi-LiDMAE In hexane at -78℃; for 1h; Metallation; Stage #2: With hexachloroethane In tetrahydrofuran at -78 - 0℃; for 1h; Condensation; | 74% |
Multi-step reaction with 2 steps 1: 83 percent / LiBF4, 20 percentF2/N2 / acetonitrile / -40 °C 2: 1 percent Chromat. / Et3N / 0.08 h / Ambient temperature View Scheme |
Conditions | Yield |
---|---|
With 2-methyl-but-2-ene; trans-dioxo(5,10,15,20-tetramesitylporphirinato)ruthenium(VI) In benzene at 30℃; for 15h; | 94% |
With (4,4′-di-tert-butyl-2,2′-bipyridine)bis[(2-pyridinyl)phenyl]iridium(III) hexafluorophosphate; di-tert-butyl 1,4-dihydro-2,6-dimethyl-3,5-pyridine-dicarboxylate In acetonitrile at 20℃; for 0.75h; Inert atmosphere; Irradiation; chemoselective reaction; | 92% |
With ammonium formate; silica gel; zinc In methanol at 20℃; for 0.166667h; chemoselective reaction; | 88% |
Conditions | Yield |
---|---|
With chlorine at 170℃; for 0.00666667h; Temperature; Inert atmosphere; Irradiation; | 89% |
With chlorine at 150 - 195℃; Concentration; Temperature; UV-irradiation; | 84.56% |
With chlorine at 175℃; Temperature; UV-irradiation; Gas phase; Large scale; | 81.36% |
With phosphorus pentachloride at 210 - 220℃; |
Conditions | Yield |
---|---|
With copper(l) iodide; zinc In ethanol at 55 - 60℃; for 3h; | A n/a B 75% |
Conditions | Yield |
---|---|
With copper(I) oxide; tetramethlyammonium chloride; L-proline In ethanol at 110℃; for 96h; Inert atmosphere; | 75% |
Conditions | Yield |
---|---|
Stage #1: 2-chloropyridine With fluorine In dichloromethane at -78 - -50℃; Stage #2: p-nitrophenyl isocyanide In dichloromethane at -50 - 0℃; for 4h; | A 22% B 68% C n/a |
6-chloro-2-methoxypyridine
2,6-dichloropyridine
Conditions | Yield |
---|---|
With trichlorophosphate In N,N-dimethyl-formamide at 105℃; for 18h; | 54% |
With N,N-dimethyl-formamide; trichlorophosphate at 105℃; for 18h; | 54% |
2-chloro-6-ethoxy-pyridine
2,6-dichloropyridine
Conditions | Yield |
---|---|
With N,N-dimethyl-formamide; trichlorophosphate at 105℃; for 18h; | 46% |
2-benzyloxy-6-chloro-pyridine
2,6-dichloropyridine
Conditions | Yield |
---|---|
With N,N-dimethyl-formamide; trichlorophosphate at 105℃; for 18h; | 41% |
pyridine
tert-Butyl peroxybenzoate
A
3-Chloropyridine
B
2-chloropyridine
C
4-Chloropyridine
D
2,6-dichloropyridine
Conditions | Yield |
---|---|
Stage #1: pyridine With chlorine; di-tert-butyl peroxide In tetrachloromethane; water at 231 - 244℃; for 0.00361111 - 0.00722222h; Stage #2: tert-Butyl peroxybenzoate Product distribution / selectivity; | A n/a B 35% C n/a D n/a |
Conditions | Yield |
---|---|
With chlorine at 270 - 300℃; Leiten ueber Bimsstein; | |
With steam; chlorine at 350℃; Leiten ueber Siliciumcarbid; | |
With chlorine at 350 - 420℃; Leiten ueber Bimsstein; | |
With chlorine at 70℃; for 48h; Inert atmosphere; Irradiation; |
6-chloro-2-hydroxypyridine
2,6-dichloropyridine
Conditions | Yield |
---|---|
With trichlorophosphate at 120℃; |
2,6-dichloro-isonicotinic acid ; silver (I)-compound
2,6-dichloropyridine
Conditions | Yield |
---|---|
at 100℃; im Kohlendioxyd-Strom; |
2-chloropyridine
A
2,6-dichloropyridine
B
2,6-difluoro pyridine
C
2-chloro-6-fluoropyridine
Conditions | Yield |
---|---|
With fluorine at 0℃; |
C5H4ClFN(1+)*BF4(1-)
A
2-chloropyridine
B
2,6-dichloropyridine
C
2,6-difluoro pyridine
D
2-chloro-6-fluoropyridine
Conditions | Yield |
---|---|
With triethylamine for 0.0833333h; Ambient temperature; | A 3 % Chromat. B 1 % Chromat. C 2.5 % Chromat. D 72 % Chromat. |
tetrachloromethane
2,6-dichloroisonicotinoyl chloride
2,6-dichloropyridine
Conditions | Yield |
---|---|
Hydrogenation; |
2,6-dichloropyridine
Conditions | Yield |
---|---|
at 100℃; Erhitzen im Kohlendioxyd-Strom; |
Conditions | Yield |
---|---|
at 270 - 300℃; | |
at 350 - 420℃; |
2,6-dichloropyridine N-oxide
3-Chlorostyrene
A
2,6-dichloropyridine
B
(R)-meta-chlorostyrene oxide
C
(S)-3-chlorostyrene oxide
Conditions | Yield |
---|---|
chiral ruthenium porphyrin complex catalyst In toluene at -10℃; for 48h; Title compound not separated from byproducts.; |
4-vinylbenzyl chloride
2,6-dichloropyridine N-oxide
A
2,6-dichloropyridine
B
(R)-2-(4-chlorophenyl)oxirane
C
(2S)-2-(4-chlorophenyl)oxirane
Conditions | Yield |
---|---|
chiral ruthenium porphyrin complex catalyst In toluene at -10℃; for 48h; Title compound not separated from byproducts.; |
1-propenylbenzene
2,6-dichloropyridine N-oxide
A
2,6-dichloropyridine
B
(1S,2S)-(-)-1-phenyl-1-propene oxide
C
(+)-(R,R)-β-methylstyrene oxide
Conditions | Yield |
---|---|
chiral ruthenium porphyrin complex catalyst In toluene at -10℃; for 48h; Title compound not separated from byproducts.; |
styrene
2,6-dichloropyridine N-oxide
A
2,6-dichloropyridine
B
(R)-Styrene oxide
C
(S)-styrene oxide
Conditions | Yield |
---|---|
chiral ruthenium porphyrin complex catalyst In toluene at -10℃; for 48h; Title compound not separated from byproducts.; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: water; hydrochloric acid / 160 °C / Unter Druck 2: phosphoryl chloride / 120 °C View Scheme |
Conditions | Yield |
---|---|
With sodium methylate at 20 - 60℃; for 24h; | 100% |
With sodium hydroxide at 70 - 75℃; Concentration; | 97.5% |
With sodium hydroxide for 8h; Reflux; | 88% |
Conditions | Yield |
---|---|
In methanol at 60℃; for 24h; | 100% |
In toluene for 24h; |
2,6-dichloropyridine
3-pyridylboronic acid
N,N'-bis(3-pyridyl)-2,6-diaminopyridine
Conditions | Yield |
---|---|
With potassium phosphate; tris(dibenzylideneacetone)dipalladium (0); tricyclohexylphosphine In 1,4-dioxane; water at 100℃; for 18h; | 100% |
2,6-dichloropyridine
2-tri-n-butylstannylpyridine
6-Chloro-[2,2']bipyridinyl
Conditions | Yield |
---|---|
tetrakis(triphenylphosphine) palladium(0) In toluene for 11h; Reflux; | 100% |
tetrakis(triphenylphosphine) palladium(0) In toluene for 11h; Reflux; | 100% |
Pd[(PPh)3]4 In toluene for 24h; Stille cross-coupling reaction; Heating; | 69% |
2,6-dichloropyridine
3-Chlorobenzaldehyde
(3-chloro-phenyl)-(2,6-dichloro-pyridin-3-yl)-methanol
Conditions | Yield |
---|---|
Stage #1: 2,6-dichloropyridine With n-butyllithium; diethylamine In tetrahydrofuran; hexane at -80℃; for 1.5h; Inert atmosphere; Stage #2: m-Chlorobenzaldehyde In tetrahydrofuran; hexane at -78 - 20℃; for 16h; Inert atmosphere; | 100% |
2,6-dichloropyridine
cyclopentanecarbonitrile
1-(6-chloro-2-pyridyl)cyclopentane carbonitrile
Conditions | Yield |
---|---|
Stage #1: cyclopentanecarbonitrile With potassium hexamethylsilazane In tetrahydrofuran; toluene at 0℃; for 0.25h; Inert atmosphere; Stage #2: 2,6-dichloropyridine In tetrahydrofuran; toluene at 20℃; for 0.666667h; Inert atmosphere; | 100% |
2,6-dichloropyridine
Benzyl-isopropyl-amin
2-(N-benzylisopropylamino)-6-chloropyridine
Conditions | Yield |
---|---|
Stage #1: Benzyl-isopropyl-amin With n-butyllithium In hexane; toluene at -64 - 0℃; Stage #2: 2,6-dichloropyridine In hexane; toluene at 4 - 20℃; | 99% |
With n-butyllithium |
2,6-dichloropyridine
para-methylphenylmagnesium bromide
2,6-di-p-tolylpyridine
Conditions | Yield |
---|---|
With chloro(1,3-bis(pyridin-2-ylmethyl)imidazolylidene)nickel(II) hexafluorophosphate In tetrahydrofuran at 20℃; for 12h; Kumada-Corriu coupling reaction; Inert atmosphere; | 99% |
With N-heterocyclic carbene-based nickel(II) complex In tetrahydrofuran at 20℃; for 12h; Kumada reaction; | 95% |
2,6-dichloropyridine
ethanolamine
2-(6-chloro-pyridin-2-ylamino)-ethanol
Conditions | Yield |
---|---|
With pyridine at 20 - 100℃; | 99% |
2,6-dichloropyridine
2,6-di-p-tolylpyridine
Conditions | Yield |
---|---|
With N-methyl-2-phenyl-3-(dicyclohexylphosphino)-1H-indole; palladium diacetate; triethylamine; sodium t-butanolate In water at 100℃; for 18h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique; | 99% |
2,6-dichloropyridine
3-(bromomethyl)-1,1'-biphenyl
Conditions | Yield |
---|---|
Stage #1: 3-(bromomethyl)-1,1'-biphenyl With magnesium In diethyl ether at 20℃; for 1h; Reflux; Inert atmosphere; Stage #2: 2,6-dichloropyridine With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) In diethyl ether at 0℃; Reflux; Inert atmosphere; | 99% |
Conditions | Yield |
---|---|
Stage #1: benzyl alcohol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.5h; Stage #2: 2,6-dichloropyridine In N,N-dimethyl-formamide; mineral oil at 80℃; for 25h; | 99% |
Conditions | Yield |
---|---|
With sodium hydroxide; tetrabutylammomium bromide In water; benzene for 6h; Heating; | 98% |
2,6-dichloropyridine
sodium thiomethoxide
2-chloro-6-methylsulphenylpyridine
Conditions | Yield |
---|---|
With tetrabutylammomium bromide In water; benzene for 6h; Heating; | 98% |
With tetrabutyl-ammonium chloride In water; benzene for 6h; Heating; | 98% |
Conditions | Yield |
---|---|
With caesium carbonate; tri tert-butylphosphoniumtetrafluoroborate; Pd(0)-triolefinic macrocyclic catalyst In xylene for 72h; Suzuki cross-coupling; Heating; | 98% |
With potassium phosphate; [NiCl(Ph2PCH2CH2OH)2(H2O)]Cl In isopropyl alcohol at 80℃; for 4h; Suzuki coupling reaction; | 96% |
With sodium hydroxide; polyaniline-supported palladium In water at 100℃; for 6h; Suzuki coupling; | 96% |
2,6-dichloropyridine
bis(pinacol)diborane
2,6-dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Conditions | Yield |
---|---|
Stage #1: bis(pinacol)diborane With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine In tert-butyl methyl ether Inert atmosphere; Stage #2: 2,6-dichloropyridine In tert-butyl methyl ether at 80℃; for 0.05h; Inert atmosphere; Microwave irradiation; | 98% |
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; cyclopentyl methyl ether; 1,1'-di(pyridin-2-yl)-1,1',3,3'-tetrahydro-2,2'-bibenzo[d][1,3,2]diazaborole at 100℃; for 16h; Schlenk technique; Inert atmosphere; | 97% |
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine In tert-butyl methyl ether at 20℃; for 16h; Glovebox; Sealed tube; regioselective reaction; | 96% |
2,6-dichloropyridine
tetrakis(triphenylphosphine) palladium(0)
Conditions | Yield |
---|---|
In toluene under N2, stirring at 90°C for 4 h, (room temperature, overnight), concn., diln. with diethyl ether; dissolved in CH2Cl2, treated with charcoal, filtration, addn. of MeOH, pptn. with Et2O, elem. anal.; | 98% |
In toluene addn. of excess 2,6-dichloropyridine to Pd-compound in toluene; heatingto 90°C; standing 5 h at room temperature, recrystn. from dichloromethane-methanol, elem. anal.; | 95% |
With pyrographite In toluene (N2); soln. of Py-deriv. and Pd complex was stirred at 90°C for 12 h; mixt. was concd. and pptd. with Et2O/hexane 2/1, ppt. dissolved in CH2Cl2, treated with charcoal, filtered, concd. and pptd. with Et2O; elem. anal.; | 90% |
Conditions | Yield |
---|---|
With potassium phosphate In 1,4-dioxane at 100℃; for 16h; | 98% |
With caesium carbonate In N,N-dimethyl-formamide at 80℃; for 16h; | 72% |
With potassium phosphate In 1,4-dioxane at 100℃; for 5h; metal-free Buchwald-Hartwig amination; Inert atmosphere; |
Conditions | Yield |
---|---|
Stage #1: 9H-carbazole With methylmagnesium chloride In tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene at 5℃; for 0.25h; Inert atmosphere; Schlenk technique; Stage #2: 2,6-dichloropyridine With 2,6-bis(2,4,6-triisopropylphenyl)phenyl(dicyclohexylphosphine); [(2,6-bis(2,4,6-triisopropylphenyl)phenyl)dicyclohexylphosphine](allyl-η3)palladium(II) chloride In tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene at 145℃; for 3h; Reagent/catalyst; Solvent; Temperature; Glovebox; Sealed tube; Schlenk technique; | 98% |
With di-tert-butyl(2,2-diphenyl-1-methyl-1-cyclopropyl)phosphine; bis(η3-allyl-μ-chloropalladium(II)); methylmagnesium chloride In tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene at 5℃; Buchwald-Hartwig Coupling; Inert atmosphere; Reflux; | 91.2% |
Stage #1: 9H-carbazole With methylmagnesium chloride In tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene at 5 - 20℃; for 0.166667h; Inert atmosphere; Stage #2: 2,6-dichloropyridine With PdCl(π-allyl)(cyclohexyl-(1-methyl-2,2-diphenylcyclopropylphophine)) In tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene at 108 - 112℃; for 0.25h; Inert atmosphere; | 91% |
With sodium hydride In N,N-dimethyl-formamide at 20 - 160℃; for 13h; Inert atmosphere; | |
With NaH In water; N,N-dimethyl-formamide |
2,6-dichloropyridine
N,N-dimethyl-formamide
6-chloro-2-N,N-dimethylaminopyridine
Conditions | Yield |
---|---|
at 180℃; for 2h; Microwave irradiation; | 98% |
at 180℃; for 1h; Microwave irradiation; | 91% |
at 180℃; for 1h; Microwave irradiation; | 91% |
2,6-dichloropyridine
N-methylaniline
6-chloro-N-methyl-N-phenylpyridin-2-amine
Conditions | Yield |
---|---|
With potassium hexamethylsilazane In 1,4-dioxane at 25℃; for 0.5h; | 98% |
2,6-dichloropyridine
Conditions | Yield |
---|---|
Stage #1: 1-(bromomethyl)-3-isopropylbenzene With magnesium In diethyl ether at 20℃; for 1h; Reflux; Inert atmosphere; Stage #2: 2,6-dichloropyridine With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) In diethyl ether at 0℃; Reflux; Inert atmosphere; | 98% |
Conditions | Yield |
---|---|
With C84H64Cl3N3Pd; potassium carbonate In ethanol at 80℃; for 2h; Suzuki-Miyaura Coupling; | 98% |
2,6-dichloropyridine
Thien-3-ylboronic acid
2,6-di-(3-thienyl)pyridine
Conditions | Yield |
---|---|
With C84H64Cl3N3Pd; potassium carbonate In ethanol at 80℃; for 2h; Suzuki-Miyaura Coupling; | 98% |
pyrrolidine
2,6-dichloropyridine
A
2-chloro-6-pyrrolidine-1-ylpyridine
Conditions | Yield |
---|---|
at 80℃; under 6000480 Torr; for 72h; | A 3% B 97% |
2,6-dichloropyridine
p-tolylzinc(II) chloride
2,6-di-p-tolylpyridine
Conditions | Yield |
---|---|
With C21H18N8Ni2O(2+)*2F6P(1-) In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 20 - 80℃; Negishi coupling reaction; | 97% |
Conditions | Yield |
---|---|
With nickel(II) chloride hexahydrate; C32H39N2OP In tetrahydrofuran at 25℃; for 20h; Kumada coupling reaction; Inert atmosphere; | 97% |
With C18H16N6NiO2 In tetrahydrofuran at 30℃; for 2h; Kumada Cross-Coupling; Schlenk technique; | 90% |
With CpPd(SIMes)Cl; lithium chloride In tetrahydrofuran; 1,2-dimethoxyethane at 20℃; for 36h; Kumada-Tamao-Corriu cross-coupling reaction; Inert atmosphere; | 79% |
Stage #1: 2,6-dichloropyridine With Ni{N(SiMe3)(C6H3-2,6-Pri2)}2 In diethyl ether at -35℃; for 0.333333h; Inert atmosphere; Stage #2: phenylmagnesium bromide In diethyl ether at 20℃; for 6h; Inert atmosphere; | 92 %Spectr. |
2,6-dichloropyridine
N-phenyl-2-cyclohexylamine
6-chloro-N-cyclohexyl-N-phenylpyridin-2-amine
Conditions | Yield |
---|---|
With potassium hexamethylsilazane In 1,4-dioxane at 25℃; for 4h; | 97% |
2,6-dichloropyridine
diphenylamine
6-chloro-N,N-diphenylpyridin-2-amine
Conditions | Yield |
---|---|
With potassium hexamethylsilazane In 1,4-dioxane at 25℃; for 5h; | 97% |
Conditions | Yield |
---|---|
In dimethyl sulfoxide | A 96.3% B n/a |