Product Name

  • Name

    3-Glycidoxypropyltrimethoxysilane

  • EINECS 219-784-2
  • CAS No. 2530-83-8
  • Article Data10
  • CAS DataBase
  • Density 1.047 g/cm3
  • Solubility Miscible with alcohols, ketones and aliphatic or aromatic hydrocarbons. Immiscible with water.
  • Melting Point -50 °C
  • Formula C9H20O5Si
  • Boiling Point 299.4 °C at 760 mmHg
  • Molecular Weight 236.34
  • Flash Point 81.9 °C
  • Transport Information
  • Appearance Colorless transparent liquid
  • Safety 28A-26
  • Risk Codes 36/38-21
  • Molecular Structure Molecular Structure of 2530-83-8 (3-Glycidoxypropyltrimethoxysilane)
  • Hazard Symbols HarmfulXn
  • Synonyms ((3-(Trimethoxysilyl)propoxy)methyl)oxirane;(3-(Glycidyloxy)propyl)trimethoxysilane;(3-Glycidoxypropyl)trimethoxysilane;1-(Glycidyloxy)-3-(trimethoxysilyl)propane;3-(2,3-Epoxypropoxy)propyltrimethoxysilane;Glycidyl 3-(trimethoxysilyl)propyl ether;Glycidyloxypropyltrimethoxysilane;
  • PSA 49.45000
  • LogP 0.67000

Synthetic route

Allyl glycidyl ether
106-92-3

Allyl glycidyl ether

trimethoxysilane
2487-90-3

trimethoxysilane

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

Conditions
ConditionsYield
Stage #1: trimethoxysilane; C13H28N2OPtSi2 In xylene for 0.0833333h; Inert atmosphere; Reflux;
Stage #2: Allyl glycidyl ether In xylene for 2h; Product distribution / selectivity; Reflux;		82%
80%
With 2C4H9O(1-)*Ni(2+)*(x)KCl In tetrahydrofuran at 20℃; for 12h; Glovebox; Inert atmosphere;61%
Allyl glycidyl ether
106-92-3

Allyl glycidyl ether

trimethoxysilane
2487-90-3

trimethoxysilane

A

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

B

(Z)-1-propenyl glycidyl ether

(Z)-1-propenyl glycidyl ether

Conditions
ConditionsYield
With acetic acid; platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex at 160℃; Product distribution / selectivity; tube reactor;
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex; 2-Ethylhexanoic acid at 100℃; for 2h; Catalytic behavior; Reagent/catalyst; Temperature;
...Expand
Allyl glycidyl ether
106-92-3

Allyl glycidyl ether

trimethoxysilane
2487-90-3

trimethoxysilane

A

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

B

(Z)-1-propenyl glycidyl ether

(Z)-1-propenyl glycidyl ether

C

(E)-1-propenyl glycidyl ether

(E)-1-propenyl glycidyl ether

Conditions
ConditionsYield
platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex at 160℃; Product distribution / selectivity; tube reactor;
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex at 160℃; Temperature;
...Expand
phenyl(2,4,6-trimethylbenzoyl)phosphinic acid

phenyl(2,4,6-trimethylbenzoyl)phosphinic acid

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

(2,4,6-trimethylbenzoyl)phenylphosphinic acid 2-hydroxy-[3-(3-trimethoxysilyl)propyloxy] propyl ester

(2,4,6-trimethylbenzoyl)phenylphosphinic acid 2-hydroxy-[3-(3-trimethoxysilyl)propyloxy] propyl ester

Conditions
ConditionsYield
In n-heptane at 20℃; for 12h; Inert atmosphere;100%
phenyl(2,4,6-trimethylbenzoyl)phosphinic acid

phenyl(2,4,6-trimethylbenzoyl)phosphinic acid

2-Isocyanatoethyl methacrylate
30674-80-7

2-Isocyanatoethyl methacrylate

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

C32H46NO11PSi

C32H46NO11PSi

Conditions
ConditionsYield
With triethylamine In n-heptane at 20℃; Inert atmosphere;100%
...Expand
3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

2-Amino-5-mercapto-1,3,4-thiadiazole
2349-67-9

2-Amino-5-mercapto-1,3,4-thiadiazole

C11H23N3O5S2Si

C11H23N3O5S2Si

Conditions
ConditionsYield
Stage #1: 2-Amino-5-mercapto-1,3,4-thiadiazole In methanol
Stage #2: 3-glycidoxypropyltrimethoxysilane In methanol at 65℃; for 18h;		100%
In methanol at 65℃; for 18h;
3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

5-amino-3-mercapto-4H-[1,2,4]triazole
16691-43-3

5-amino-3-mercapto-4H-[1,2,4]triazole

C11H24N4O5SSi

C11H24N4O5SSi

Conditions
ConditionsYield
Stage #1: 5-amino-3-mercapto-4H-[1,2,4]triazole In methanol
Stage #2: 3-glycidoxypropyltrimethoxysilane In methanol at 65℃; for 18h; Solvent; Temperature;		100%
In methanol at 65℃; for 18h; Solvent;
3-(1H-imidazol-1-yl)propan-1-amine
5036-48-6

3-(1H-imidazol-1-yl)propan-1-amine

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

C15H31N3O5Si
1204776-56-6

C15H31N3O5Si

Conditions
ConditionsYield
In tetrahydrofuran at 95℃; for 6h; Inert atmosphere;98%
3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

C104H203N9O35Si8

C104H203N9O35Si8

C110H211N9O37Si9

C110H211N9O37Si9

Conditions
ConditionsYield
With titanium(IV) isopropylate In methanol; toluene Heating;97%
C14H18O5S
1254067-29-2

C14H18O5S

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

C23H38O10SSi
1254067-30-5

C23H38O10SSi

Conditions
ConditionsYield
With triethylamine In dichloromethane at 40℃; Inert atmosphere;97%
phosgene
75-44-5

phosgene

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

[1-(chloromethyl)-2-(3-trimethoxysilylpropoxy)ethyl]carbonochloridate

[1-(chloromethyl)-2-(3-trimethoxysilylpropoxy)ethyl]carbonochloridate

Conditions
ConditionsYield
With tetrabutyl-ammonium chloride at 15 - 20℃; for 10h; Inert atmosphere;96%
3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

1,3-propane diol monoglycidyl ether

1,3-propane diol monoglycidyl ether

Conditions
ConditionsYield
Stage #1: 3-glycidoxypropyltrimethoxysilane With ammonium hydrogen difluoride In water at 20℃; for 1h;
Stage #2: With dihydrogen peroxide In water at 20℃; for 4h; Fleming-Tamao Oxidation;		95%
3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

allyl bromide
106-95-6

allyl bromide

3-amino-1H-1,2,4-triazole-5-thiol
118025-46-0, 118025-48-2, 118025-49-3, 118025-50-6, 118025-51-7

3-amino-1H-1,2,4-triazole-5-thiol

3-[2-hydroxy-4-oxa-7-(trimethoxysilanyl)heptylamino]-5-(2-propenylthio)-4H-1,2,4-triazole

3-[2-hydroxy-4-oxa-7-(trimethoxysilanyl)heptylamino]-5-(2-propenylthio)-4H-1,2,4-triazole

Conditions
ConditionsYield
Stage #1: allyl bromide; 3-amino-1H-1,2,4-triazole-5-thiol With triethylamine In N,N-dimethyl-formamide at 70℃; for 24h;
Stage #2: 3-glycidoxypropyltrimethoxysilane In N,N-dimethyl-formamide at 70℃; for 18h;		93%
...Expand
3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

C60H110O35Si10

C60H110O35Si10

Conditions
ConditionsYield
With tetraethylammonium hydroxide In propan-1-ol; water at 50℃; for 8h; Reagent/catalyst; Solvent; Temperature;92%
carbon dioxide
124-38-9

carbon dioxide

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

4-((3-(trimethoxysilyl)propoxy)methyl)-1,3-dioxolan-2-one

4-((3-(trimethoxysilyl)propoxy)methyl)-1,3-dioxolan-2-one

Conditions
ConditionsYield
With N,N-dimethyl-formamide at 160℃; under 37503 Torr; for 15h;86%
With bis(2-hydroxyethyl) bis-(quaternary ammonium)iodide salt immobilized on ordered mesoporous organosilica at 100℃; under 7500.75 Torr; for 24h; Pressure; Temperature; Autoclave;85.1%
With tetra-(n-butyl)ammonium iodide at 105℃; under 775.252 Torr; for 20h; Schlenk technique;
With tetra-(n-butyl)ammonium iodide In neat (no solvent) at 105℃; under 775.252 Torr; for 20h; Schlenk technique; Sealed tube; Green chemistry;
triisopropanolamine
122-20-3

triisopropanolamine

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

3,7,10-trimethyl-1-(3-(oxiran-2-ylmethoxy)propyl)-2,8,9-trioxa-5-aza-1-silabicyclo[3.3.3]undecane
1026852-18-5

3,7,10-trimethyl-1-(3-(oxiran-2-ylmethoxy)propyl)-2,8,9-trioxa-5-aza-1-silabicyclo[3.3.3]undecane

Conditions
ConditionsYield
With titanium(IV) isopropylate In methanol; toluene for 18h; Heating;85%
1-methyl-piperazine
109-01-3

1-methyl-piperazine

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

A

2,2-dimethoxy-8-(4-methylpiperazinyl)methyl-1,6-dioxa-2-silacyclooctane
1222257-17-1

2,2-dimethoxy-8-(4-methylpiperazinyl)methyl-1,6-dioxa-2-silacyclooctane

B

C26H56N4O8Si2
1222257-23-9

C26H56N4O8Si2

C

C27H60N4O9Si2
1222257-21-7

C27H60N4O9Si2

Conditions
ConditionsYield
With sodium methylate In methanol; toluene Product distribution / selectivity; Reflux;A 84%
B n/a
C n/a
...Expand
C6H6F9N3O6S3(2-)*2Li(1+)

C6H6F9N3O6S3(2-)*2Li(1+)

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

C15H26F9N3O11S3Si(2-)*2Li(1+)

C15H26F9N3O11S3Si(2-)*2Li(1+)

Conditions
ConditionsYield
In tetrahydrofuran at 60℃; for 2h; Inert atmosphere;81%
3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

C78H153N7O27Si6

C78H153N7O27Si6

C84H161N7O29Si7

C84H161N7O29Si7

Conditions
ConditionsYield
With titanium(IV) isopropylate In methanol; toluene Heating;80.9%
3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

3-amino-1H-1,2,4-triazole-5-thiol
118025-46-0, 118025-48-2, 118025-49-3, 118025-50-6, 118025-51-7

3-amino-1H-1,2,4-triazole-5-thiol

3-[2-hydroxy-4-oxa-7-(trimethoxysilanyl)heptylamino]-5-(ethoxycarbonylmethylthio)-4H-1,2,4-triazole

3-[2-hydroxy-4-oxa-7-(trimethoxysilanyl)heptylamino]-5-(ethoxycarbonylmethylthio)-4H-1,2,4-triazole

Conditions
ConditionsYield
Stage #1: chloroacetic acid ethyl ester; 3-amino-1H-1,2,4-triazole-5-thiol With triethylamine In N,N-dimethyl-formamide at 75℃; for 24h;
Stage #2: 3-glycidoxypropyltrimethoxysilane In N,N-dimethyl-formamide at 70℃; for 18h;		79%
...Expand
triethanolamine
102-71-6

triethanolamine

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

1-(3-Oxiranylmethoxy-propyl)-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undecane

1-(3-Oxiranylmethoxy-propyl)-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undecane

Conditions
ConditionsYield
In methanol; toluene for 16h; Heating;78%
C33H62O4

C33H62O4

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

C50H96O12Si2

C50H96O12Si2

Conditions
ConditionsYield
With trifluoroacetic acid In toluene at 120 - 140℃; for 4h; Inert atmosphere;78%
3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

1-((2-Hydroxy-ethyl)-{2-hydroxy-3-[3-(3,7,10-trimethyl-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undec-1-yl)-propoxy]-propyl}-amino)-3-[3-(3,7,10-trimethyl-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undec-1-yl)-propoxy]-propan-2-ol

1-((2-Hydroxy-ethyl)-{2-hydroxy-3-[3-(3,7,10-trimethyl-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undec-1-yl)-propoxy]-propyl}-amino)-3-[3-(3,7,10-trimethyl-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undec-1-yl)-propoxy]-propan-2-ol

C38H73N3O13Si3

C38H73N3O13Si3

Conditions
ConditionsYield
With titanium(IV) isopropylate In methanol; toluene Heating;75%
1-methyl-piperazine
109-01-3

1-methyl-piperazine

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

A

2,2-dimethoxy-8-(4-methylpiperazinyl)methyl-1,6-dioxa-2-silacyclooctane
1222257-17-1

2,2-dimethoxy-8-(4-methylpiperazinyl)methyl-1,6-dioxa-2-silacyclooctane

B

C14H32N2O5Si
1222257-19-3

C14H32N2O5Si

C

C26H56N4O8Si2
1222257-23-9

C26H56N4O8Si2

Conditions
ConditionsYield
at 140 - 149℃; Product distribution / selectivity;A 75%
B n/a
C n/a
...Expand
3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

1-(Bis-{2-hydroxy-3-[3-(3,7,10-trimethyl-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undec-1-yl)-propoxy]-propyl}-amino)-3-[3-(3,7,10-trimethyl-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undec-1-yl)-propoxy]-propan-2-ol

1-(Bis-{2-hydroxy-3-[3-(3,7,10-trimethyl-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undec-1-yl)-propoxy]-propyl}-amino)-3-[3-(3,7,10-trimethyl-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undec-1-yl)-propoxy]-propan-2-ol

C51H98N4O17Si4
1026552-21-5

C51H98N4O17Si4

Conditions
ConditionsYield
With titanium(IV) isopropylate In methanol; toluene Heating;54%
morpholine
110-91-8

morpholine

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

A

1,1-dimethoxy-3-morpholinomethyl-2,5-dioxa-1-silacyclooctane
1222257-39-7

1,1-dimethoxy-3-morpholinomethyl-2,5-dioxa-1-silacyclooctane

B

1-morpholino-3-(3-trimethoxysilylpropoxy)propan-2-ol
1222257-40-0

1-morpholino-3-(3-trimethoxysilylpropoxy)propan-2-ol

C

C24H50N2O10Si2
1222257-42-2

C24H50N2O10Si2

D

C25H54N2O11Si2

C25H54N2O11Si2

Conditions
ConditionsYield
With sodium methylate In methanol; toluene at 116 - 140℃;A 53%
B n/a
C n/a
D n/a
...Expand
phenyl(2,4,6-trimethylbenzoyl)phosphinic acid

phenyl(2,4,6-trimethylbenzoyl)phosphinic acid

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

A

(2,4,6-trimethylbenzoyl)phenylphosphinic acid 2-hydroxy-[3-(3-trimethoxysilyl)propyloxy] propyl ester

(2,4,6-trimethylbenzoyl)phenylphosphinic acid 2-hydroxy-[3-(3-trimethoxysilyl)propyloxy] propyl ester

B

1,1-dimethoxy-3-[methyl(2,4,6-trimethylbenzoyl)phenylphosphinate]-2,5-dioxa-1-silacyclooctane

1,1-dimethoxy-3-[methyl(2,4,6-trimethylbenzoyl)phenylphosphinate]-2,5-dioxa-1-silacyclooctane

Conditions
ConditionsYield
In toluene at 60℃; for 6h;A 5%
B 35%
...Expand
propan-1-ol
71-23-8

propan-1-ol

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

A

C13H28O5Si

C13H28O5Si

B

C11H24O5Si

C11H24O5Si

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1.5h; Inert atmosphere;A 10%
B 18.5%
...Expand
di(pyridin-2-yl)amine
1202-34-2

di(pyridin-2-yl)amine

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

C19H29N3O5Si

C19H29N3O5Si

Conditions
ConditionsYield
In methanol for 65h; Heating;
bis[2-(2-pyridyl)ethyl]amine
15496-36-3

bis[2-(2-pyridyl)ethyl]amine

3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

C23H37N3O5Si

C23H37N3O5Si

Conditions
ConditionsYield
In methanol for 65h; Heating;
3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

bis[(2-pyridyl)methyl]amine
1539-42-0

bis[(2-pyridyl)methyl]amine

C21H33N3O5Si

C21H33N3O5Si

Conditions
ConditionsYield
In methanol for 65h; Heating;
3-glycidoxypropyltrimethoxysilane
2530-83-8

3-glycidoxypropyltrimethoxysilane

(2-pyridin-2-yl-ethyl)-pyridin-2-ylmethyl-amine
15395-61-6

(2-pyridin-2-yl-ethyl)-pyridin-2-ylmethyl-amine

C22H35N3O5Si

C22H35N3O5Si

Conditions
ConditionsYield
In methanol for 65h; Heating;

3-Glycidoxypropyltrimethoxysilane Specification

The 3-Glycidoxypropyltrimethoxysilane, with the CAS registry number 2530-83-8, is also known as Trimethoxy[3-(2-oxiranylmethoxy)propyl]silane.It belongs to the product organic raw material. Its EINECS number is 219-784-2. This chemical's molecular formula is C9H20O5Si and molecular weight is 236.34. What's more,Its systematic name is gamma-Glycidoxypropyltrimethoxysilane.3-Glycidoxypropyltrimethoxysilane may cause damage to health. It is harmful in contact with skin and irritating to eyes and skin.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Physical properties about 3-Glycidoxypropyltrimethoxysilane are:
(1)ACD/LogP: 1.434; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.43; (4)ACD/LogD (pH 7.4): 1.43; (5)ACD/BCF (pH 5.5): 7.25; (6)ACD/BCF (pH 7.4): 7.25; (7)ACD/KOC (pH 5.5): 143.65; (8)ACD/KOC (pH 7.4): 143.65; (9)#H bond acceptors: 5; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 9; (12)Index of Refraction: 1.436; (13)Molar Refractivity: 59.018 cm3; (14)Molar Volume: 225.575 cm3; (15)Surface Tension: 29.4689998626709 dyne/cm; (16)Density: 1.048 g/cm3; (17)Flash Point: 81.947 °C; (18)Enthalpy of Vaporization: 51.777 kJ/mol; (19)Boiling Point: 299.352 °C at 760 mmHg; (20)Vapour Pressure: 0.0020000000949949 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES:O(CCC[Si](OC)(OC)OC)CC1OC1;
(2)Std. InChI:InChI=1S/C9H20O5Si/c1-10-15(11-2,12-3)6-4-5-13-7-9-8-14-9/h9H,4-8H2,1-3H3;
(3)Std. InChIKey:BPSIOYPQMFLKFR-UHFFFAOYSA-N;

The toxicity data of 3-Glycidoxypropyltrimethoxysilane as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rabbit LD50 skin 3970uL/kg (3.97mL/kg)   American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.
rat LCLo inhalation 5300mg/m3/4H (5300mg/m3)   Office of Toxic Substances Report. Vol. OTS215156,
rat LCLo inhalation 5300mg/m3/4H (5300mg/m3) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE Office of Toxic Substances Report. Vol. OTS215156,
rat LD50 oral 22600uL/kg (22.6mL/kg)   Union Carbide Data Sheet. Vol. 2/11/1964,

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View