3-Methyl-2-buten-1-ol supplier

Name
3-Methyl-2-buten-1-ol
EINECS 209-141-4
CAS No. 556-82-1
Article Data189
CAS DataBase
Density 0.844 g/cm³
Solubility water: 170 g/L (20 °C)
Melting Point -86oC
Formula C₅H₁₀O
Boiling Point 141.5 °C at 760 mmHg
Molecular Weight 86.1338
Flash Point 43.3 °C
Transport Information UN 1987 3/PG 3
Appearance colorless liquid with fruity odor
Safety 26-36-37-23-16
Risk Codes 10-22-36/37/38-38-21/22
Molecular Structure
Hazard Symbols Xn
Synonyms 2-Methyl-2-buten-4-ol;3,3-Dimethylallyl alcohol;3-Methyl-2-buten-1-ol;3-Methyl-2-butene-1-ol;3-Methyl-2-butenol;3-Methyl-2-butenyl alcohol;3-Methylcrotyl alcohol;Dimethylallyl alcohol;Isopent-2-en-1-ol;NSC 158709;Prenol;Prenyl alcohol;g,g-Dimethylallyl alcohol;
PSA 20.23000
LogP 0.94490

Synthetic route

: 107-86-8
3,3-dimethyl acrylaldehyde

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With acetylacetonatodicarbonylrhodium(l); trifluorormethanesulfonic acid; carbon monoxide; N-(5-diphenylphosphanylpyrrole-2-carbonyl)guanidine; hydrogen In dichloromethane at 40℃; under 15001.5 Torr; for 20h; Autoclave;	99%
With indium tri-isopropoxide supported on mesoporous SBA-15 In isopropyl alcohol at 80℃; for 7h; Reagent/catalyst; Meerwein-Ponndorf-Verley Reduction; Inert atmosphere; Schlenk technique; chemoselective reaction;	89.6%
With Triisopropyl borate; isopropyl alcohol at 27℃; for 15h; Kinetics; Reagent/catalyst; Meerwein-Ponndorf-Verley reduction; Inert atmosphere; chemoselective reaction;	87.9%

: 763-32-6
2-methyl-1-buten-4-ol

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With lithium hexafluorophosphate at 0℃; for 8h; Reagent/catalyst; Temperature; Irradiation; Inert atmosphere;	97%
With palladium 10% on activated carbon; oxygen at 80℃; under 3750.38 Torr; for 5h; Reagent/catalyst; Time; Concentration;	53.05%
With pyridine; 2-methyl-2-phenyloxirane; iron pentacarbonyl; carbon monoxide at 70℃; under 3750.38 Torr; for 42h; Reagent/catalyst; Temperature; Inert atmosphere; Autoclave;
With 1,3-bis-(diphenylphosphino)propane; hydrogen; palladium diacetate In acetone at 55℃; under 5250.53 Torr; for 1h; Temperature; Pressure; Autoclave;

: 870-63-3
prenyl bromide

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With Amberlyst A 26; carbonate form In tetrahydrofuran for 1h; Heating;	95%
Multi-step reaction with 2 steps 1: NaBH4 / ethanol / 2 h / 15 - 20 °C 2: H2O2 / 2 h / 15 - 20 °C / var. oxidants and time. View Scheme
Multi-step reaction with 4 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 80 °C / Inert atmosphere 2.1: potassium peroxomonosulfate / methanol; water / 12 h / 0 - 20 °C / Inert atmosphere 3.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 - 0 °C / Inert atmosphere 3.2: 0 - 20 °C / Inert atmosphere 4.1: water; dihydrogen peroxide; sodium hydroxide / tetrahydrofuran; hexane / 0.5 h / 20 °C / Inert atmosphere View Scheme
Multi-step reaction with 4 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 80 °C / Inert atmosphere 2.1: potassium peroxomonosulfate / methanol; water / 12 h / 0 - 20 °C / Inert atmosphere 3.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 - 0 °C / Inert atmosphere 3.2: 0 - 20 °C / Inert atmosphere 4.1: water; dihydrogen peroxide; sodium hydroxide / tetrahydrofuran; hexane / 0.5 h / 20 °C / Inert atmosphere View Scheme

: 71821-61-9
3-methyl-1-(trimethylsilyloxy)but-2-ene

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With tris paraperiodate In benzene Heating;	95%

: 1191-16-8
3-methylbut-2-enyl acetate

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With sodium hydroxide at 100℃; for 2.5h;	95%

: 503-60-6
3,3-dimethyl-allyl chloride

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With sodium hydrogencarbonate; sodium dodecylbenzenesulfonate In cyclohexane; water at 45℃; pH=8;	92.9%
Multi-step reaction with 2 steps 2: aqueous KOH-solution View Scheme

: 638-10-8
ethyl 3-methylbut-2-enoate

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃;	91%
With lithium aluminium tetrahydride In diethyl ether at 0℃; for 3h; Inert atmosphere;	72%
With diisobutylaluminium hydride In toluene at -78 - 20℃;

: 54105-78-1
1-[(tetrahydro-2H-pyran-2-yl)oxy]-3-methyl-2-butene

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With cerium(III) chloride In methanol at 20℃; for 1h; detetrahydropyranylation;	90%

: 68480-28-4
formiate de methyl-3 butene-2 ol-1

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With potassium carbonate In ethanol for 0.333333h;	84%
With potassium hydroxide

: 107-86-8
3,3-dimethyl acrylaldehyde

A: 123-51-3
i-Amyl alcohol

B: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With dmap; formic acid; hexarhodium hexadecacarbonyl; carbon monoxide In tetrahydrofuran at 30℃; under 3800 Torr; for 20h;	A 4 % Chromat. B 81%
With dmap; formic acid; hexarhodium hexadecacarbonyl; carbon monoxide In tetrahydrofuran at 30℃; under 3800 Torr; Product distribution; base effect;
With Pt3Fe; hydrogen In ethanol at 70℃; under 750.075 Torr; for 5h; Catalytic behavior; Time;
With Pt0615Fe0385; hydrogen In ethanol at 100℃; under 1800.18 Torr;

: 115-18-4
2-methyl-3-buten-2-ol

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With methanesulfonic acid In tetrahydrofuran; water at 20℃; for 12h;	74%
With sulfuric acid
With dichloro-acetic acid und anschliessende Verseifung;

: 87791-06-8
morpholide of 1-phenylthio-4-hydroxy-2-methylbut-2Z-ene-1-sulfonic acid

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With lithium In ammonia at -70℃; for 0.0833333h;	74%

: 1,7,7-trimethylbicyclo<2.2.1>hept-2-yl 3-methyl-2-butenoate

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With aluminium hydride In tetrahydrofuran at 0℃; for 2h;	70%

: 541-47-9
3-Methylbutenoic acid

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether for 1.5h; ice bath;	60%
With lithium aluminium tetrahydride In diethyl ether for 5h;	54%
With lithium aluminium tetrahydride; diethyl ether
With lithium aluminium tetrahydride In diethyl ether

: 763-32-6
2-methyl-1-buten-4-ol

A: 107-86-8
3,3-dimethyl acrylaldehyde

B: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With 5%-palladium/activated carbon; oxygen at 80℃; under 3750.38 Torr; for 5h; Reagent/catalyst; Time; Concentration;	A 8.78% B 53.06%

: 1438-14-8
2-isopropyloxirane

A: 563-80-4
3-methyl-butan-2-one

B: 763-32-6
2-methyl-1-buten-4-ol

C: 35158-25-9
2-isopropyl-5-methyl-hex-2-enal

D: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With magnesium bromide In N,N-dimethyl-formamide at 130℃; for 0.666667h; Further byproducts given;	A 52.2% B 23.2% C 8.7% D 13.7%

...Expand

: 16722-09-1
trimethylsilyloxirane

: 4238-09-9
phenyl isopropyl sulfone

A: 133827-98-2
3-Benzenesulfonyl-3-methyl-1-trimethylsilanyl-butan-1-ol

B: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran at -20 - 20℃; for 16h;	A 45% B 31%

...Expand

: 763-32-6
2-methyl-1-buten-4-ol

: 127-09-3
sodium acetate

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With sulfuric acid; hydrogen bromide; acetic acid das Acetat entsteht;

: 79-43-6
dichloro-acetic acid

: 115-18-4
2-methyl-3-buten-2-ol

A: 106-24-1
Geraniol

B: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
bei folgendem Verseifen;
und Verseifen;

...Expand

: 50-00-0
formaldehyd

: 38614-36-7
2-methylpropen-1-ylmagnesium bromide

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With diethyl ether

: 16435-50-0
1-chloro-3-pentene

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With alkali

: 107-86-8
3,3-dimethyl acrylaldehyde

: 555-31-7
aluminum isopropoxide

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With isopropyl alcohol at 110℃;
at 110℃;

: 2190-48-9
3-chloro-3-methyl-1-butene

: 141-53-7
sodium formate

A: 115-18-4
2-methyl-3-buten-2-ol

B: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With formic acid Erwaermen des Reaktionsprodukts mit wss.Kalilauge;

...Expand

: 927-68-4
bromoethyl acetate

: 67-64-1
acetone

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With tetrahydrofuran; magnesium; mercury dichloride Erhitzen des Reaktionsprodukts mit wss.Kalilauge;

: 503-60-6
3,3-dimethyl-allyl chloride

A: 115-18-4
2-methyl-3-buten-2-ol

B: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With sodium hydrogencarbonate at 50℃;

: 78-79-5
isoprene

: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With sulfuric acid; copper(II) sulfate; acetic acid at 20℃; das Acetat entsteht; Reagens 4: Hydrochinon;
With toluene-4-sulfonic acid; acetic acid das Acetat entsteht;
ueber das Dichloracetat;
With sulfuric acid; copper(II) sulfate; acetic acid at 20℃; das Acetat entsteht; Reagens 4: Hydrochinon;
ueber das Dichloracetat;

: 766-15-4
4,4-dimethyl-1,3-dioxane

A: 16302-35-5
4-methyl-3,6-dihydro-2H-pyran

B: 763-32-6
2-methyl-1-buten-4-ol

C: 2568-33-4
3-methyl-butane-1,3-diol

D: 7525-64-6
4-hydroxy-4-methyltetrahydropyran

E: 115-18-4
2-methyl-3-buten-2-ol

F: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With sulfuric acid at 120℃; for 3h; Product distribution; various catalyst, various temperature, various time, extent of conversion, solvent cyclohexane;

...Expand

: 556-82-1
3-methyl-2-buten-1-ol

: 590-86-3
isovaleraldehyde

Conditions

Conditions	Yield
With (1,5-cyclooctadiene)(pyridine)(tricyclohexylphosphine)iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; hydrogen In tetrahydrofuran at 23℃; for 0.5h;	100%
With [Os(η(5)-C5,κ-N-Cp(N))(CH3CN)2]PF6 In tetrahydrofuran-d8 at 60℃; for 1.33333h; Inert atmosphere;	93%
With {(η6-p-cymene)RuCl2}{[3-(3,5-diaza-1-azonia-7-phosphatricyclo[3.3.1.13,7]decan-1-yl)propyl]silanetriyltrioxy} supported on silica-coated ferrite nanoparticles In water at 150℃; under 5171.62 - 6205.94 Torr; for 14h; Inert atmosphere; Microwave irradiation;	87%

: 103-71-9
phenyl isocyanate

: 556-82-1
3-methyl-2-buten-1-ol

: 105902-61-2
3-methylbut-2-en-1-yl phenylcarbamate

Conditions

Conditions	Yield
In acetonitrile at 70℃; for 23h; Inert atmosphere;	100%
With triethylamine In dichloromethane at 20℃; Inert atmosphere;	88%
With triethylamine In dichloromethane at 20℃;	88%

: 110-87-2
3,4-dihydro-2H-pyran

: 556-82-1
3-methyl-2-buten-1-ol

: 54105-78-1
1-[(tetrahydro-2H-pyran-2-yl)oxy]-3-methyl-2-butene

Conditions

Conditions	Yield
With pyridinium p-toluenesulfonate In dichloromethane at 20℃; for 4h;	100%
With pyridinium p-toluenesulfonate In tetrahydrofuran	100%
With Aluminum(III) chloride hexahydrate at 30℃; for 0.5h;	98%

: 556-82-1
3-methyl-2-buten-1-ol

: 18511-56-3
(3,3-dimethyloxiranyl)methanol

Conditions

Conditions	Yield
With dihydrogen peroxide; {[CF3(CF2)7(CH2)3]3N(+)}12[WZn3(H2O)2(ZnW9O34)2] In ethyl acetate at 22℃; for 8h;	100%
With 3,3-dimethyldioxirane In acetone at 23℃; Kinetics; Further Variations:; Solvents;	100%
With tetrabutylphosphonium peroxotantalate; dihydrogen peroxide In water at 0℃; for 1.5h; Catalytic behavior; Reagent/catalyst; Schlenk technique; chemoselective reaction;	100%

: 108-24-7
acetic anhydride

: 556-82-1
3-methyl-2-buten-1-ol

: 1191-16-8
3-methylbut-2-enyl acetate

Conditions

Conditions	Yield
indium(III) chloride In acetonitrile at 20℃; for 0.5h;	100%
With zirconium(IV) chloride In dichloromethane at 20℃; for 1h;	100%
With pyridine at 20℃; for 2.5h;	99%

: 58479-61-1
tert-butylchlorodiphenylsilane

: 556-82-1
3-methyl-2-buten-1-ol

: 188263-82-3
1-((tert-butyldiphenylsilyl)oxy)-3-methyl-2-butene

Conditions

Conditions	Yield
With 1H-imidazole In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃;	100%
With 1H-imidazole In dichloromethane at 0 - 20℃; for 0.5h;	98%
With dmap; triethylamine In dichloromethane for 2h; Ambient temperature;	82%

: 5707-04-0
Phenylselenyl chloride

: 556-82-1
3-methyl-2-buten-1-ol

: 99018-46-9
3-methyl-2-(phenylselenyl)-1,3-butanediol

Conditions

Conditions	Yield
With water In acetonitrile at 20℃; for 24h;	100%
In water; acetonitrile for 2h; Ambient temperature;	86%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 556-82-1
3-methyl-2-buten-1-ol

: 114701-65-4
tert-butyldimethyl((3-methylbut-2-en-1-yl)oxy)silane

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;	100%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 6h;	94%
With 1H-imidazole In dichloromethane at 0 - 20℃;	93%

: 76-83-5
trityl chloride

: 556-82-1
3-methyl-2-buten-1-ol

: 141561-63-9
(((3-methylbut-2-en-1-yl)oxy)methanetrityl)tribenzene

Conditions

Conditions	Yield
With dmap; triethylamine In dichloromethane at 0 - 23℃;	100%
With dmap; triethylamine In dichloromethane at 0 - 23℃; Inert atmosphere;	100%
With dmap; 4 A molecular sieve; triethylamine In dichloromethane at 20℃; for 12h;	65%

: 922-69-0
1,1-dimethoxyethylene

: 556-82-1
3-methyl-2-buten-1-ol

: 76347-60-9
C9H18O3

Conditions

Conditions	Yield
at 20℃; for 0.5h; Inert atmosphere; neat (no solvent);	100%

: 1310054-46-6
TrocNHOSO2NH2

: 556-82-1
3-methyl-2-buten-1-ol

: 1310054-26-2
C8H13Cl3N2O5S

Conditions

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; Mitsunobu reaction; Cooling with ice;	100%

: 556-82-1
3-methyl-2-buten-1-ol

: 108-12-3
isopentanoyl chloride

: 89026-29-9
3-methyl-2-buten-1-yl 3-methylbutanoate

Conditions

Conditions	Yield
With pyridine; dmap In dichloromethane at 0 - 20℃; for 2.5h;	100%

: 1445-45-0
Trimethyl orthoacetate

: 556-82-1
3-methyl-2-buten-1-ol

: 7796-72-7
ethyl 3,3-dimethylpent-4-enoate

Conditions

Conditions	Yield
With phenol at 130 - 160℃; for 16h; Johnson-Claisen Rearrangement; Inert atmosphere;	100%

: 1003872-51-2
2,6-dichloro-N-cyclohexyl-pyridine-3-carboxamide

: 556-82-1
3-methyl-2-buten-1-ol

: 6-chloro-N-cyclohexyl-2-(3-methylbut-2-enoxy)pyridine-3-carboxamide

Conditions

Conditions	Yield
Stage #1: 3-methyl-2-buten-1-ol With sodium hydride In N,N-dimethyl-formamide; mineral oil for 0.75h; Inert atmosphere; Stage #2: 2,6-dichloro-N-cyclohexyl-pyridine-3-carboxamide In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 4h; Inert atmosphere;	100%

: dioctyltin dilaurate

: 41725-90-0
methyl 2-methylbut-2-enoate

: 556-82-1
3-methyl-2-buten-1-ol

: 765300-33-2
3-methyl-2-butenyl angelate

Conditions

Conditions	Yield
In toluene	99.8%

...Expand

: 4530-20-5
BOC-glycine

: 556-82-1
3-methyl-2-buten-1-ol

: 82706-45-4
tert-butoxycarbonylamino-acetic acid 3-methyl-but-2-enyl ester

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at -5 - 25℃; for 8h;	99.15%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃;	91%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃;
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 2h; Solvent; Large scale;	129 kg

: 556-82-1
3-methyl-2-buten-1-ol

: 107-86-8
3,3-dimethyl acrylaldehyde

Conditions

Conditions	Yield
With bis(acetylacetonato)dioxidomolybdenum(VI); dimethyl sulfoxide at 100℃; for 7h;	99%
With oxygen; Pd561phen60(OAc)180 In benzene at 60℃; for 24h;	99%
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen In acetonitrile at 75℃; under 760.051 Torr; for 11h;	99%

: 98-88-4
benzoyl chloride

: 556-82-1
3-methyl-2-buten-1-ol

: 5205-11-8
3-methyl-2-butenyl benzoate

Conditions

Conditions	Yield
Stage #1: benzoyl chloride; 3-methyl-2-buten-1-ol In dichloromethane at 20℃; Stage #2: With poly{trans-bicyclo[2.2.1]hept-5-ene-2,3-di(chlorocarbonyl)} In dichloromethane Heating;	99%
With dmap; triethylamine In dichloromethane at 0 - 20℃;	91%
With pyridine at 20℃; for 0.5h;	89%

: 637-69-4
4-Methoxystyrene

: 556-82-1
3-methyl-2-buten-1-ol

: 2-iodo-1-(3-methylbut-2-enyl)oxy-1-(4-methoxyphenyl)ethane

Conditions

Conditions	Yield
With N-iodo-succinimide In dichloromethane at -78 - 0℃;	99%
Stage #1: 4-Methoxystyrene; 3-methyl-2-buten-1-ol In dichloromethane at 20℃; for 0.0833333h; Stage #2: With N-iodo-succinimide In dichloromethane at -78 - 0℃; Further stages.;	99%

: 76-86-8
Triphenylsilyl chloride

: 556-82-1
3-methyl-2-buten-1-ol

: C23H24OSi

Conditions

Conditions	Yield
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 22h;	99%

: 24424-99-5
di-tert-butyl dicarbonate

: 556-82-1
3-methyl-2-buten-1-ol

: tert-butyl (3-methylbut-2-en-1-yl)carbonate

Conditions

Conditions	Yield
Stage #1: 3-methyl-2-buten-1-ol With n-butyllithium In tetrahydrofuran; hexane at 0℃; for 1.5h; Stage #2: di-tert-butyl dicarbonate In tetrahydrofuran; hexane at 0 - 24℃; for 20h;	99%

: 79-30-1
isobutyryl chloride

: 556-82-1
3-methyl-2-buten-1-ol

: 76649-23-5
3-methyl-2-butenyl isobutanoate

Conditions

Conditions	Yield
With pyridine; dmap In dichloromethane at 0 - 20℃; for 2.5h;	99%
With dmap; triethylamine In dichloromethane at 20℃; for 18h; Inert atmosphere;

: 2146-71-6
vinyl laurate

: 556-82-1
3-methyl-2-buten-1-ol

: Dodecanoic acid 3-methyl-but-2-enyl ester

Conditions

Conditions	Yield
With carbon dioxide at 46.02℃; under 66081.6 Torr; for 3.5h; Reagent/catalyst; High pressure; Supercritical conditions; Green chemistry;	99%

: 556-82-1
3-methyl-2-buten-1-ol

: 62875-08-5
(R,S)-3-methyl-1,2,3-butanetriol

Conditions

Conditions	Yield
Stage #1: 3-methyl-2-buten-1-ol With dihydrogen peroxide; bis(2,4-pentanedionato)dioxomolybdenum(VI) In acetonitrile at 30℃; Stage #2: With diphenyl sulfide regioselective reaction;	99%
Multi-step reaction with 2 steps 1: 3-chloro-benzenecarboperoxoic acid / acetonitrile / 168 h / 20 °C 2: water; perchloric acid / 0.17 h View Scheme

: 108-05-4
vinyl acetate

: 556-82-1
3-methyl-2-buten-1-ol

: 1191-16-8
3-methylbut-2-enyl acetate

Conditions

Conditions	Yield
With pseudomonas fuorescens lipase immobilized on multiwall carbon nano-tubes at 50℃; for 4h; Green chemistry;	99%

: 5416-93-3
4-Methoxyphenyl isocyanate

: 556-82-1
3-methyl-2-buten-1-ol

: 3-methylbut-2-en-1-yl (4-methoxyphenyl)carbamate

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20℃;	99%
In acetonitrile at 70℃; for 23h; Inert atmosphere;	78%

: 100-07-2
4-methoxy-benzoyl chloride

: 556-82-1
3-methyl-2-buten-1-ol

: 3-methylbut-2-en-1-yl 4-methoxybenzoate

Conditions

Conditions	Yield
With pyridine at 0 - 24℃; for 24.5h; Inert atmosphere;	99%
With pyridine at 0 - 24℃; for 24.5h;	99%

: 28131-17-1
2-(4-bromophenyl)acrylic acid

: 556-82-1
3-methyl-2-buten-1-ol

: 3-methylbut-2-en-1-yl 2-(4-bromophenyl)acrylate

Conditions

Conditions	Yield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 3h; Inert atmosphere;	99%

: C18H16O8

: 556-82-1
3-methyl-2-buten-1-ol

: 1334485-04-9
3-methylbut-2-enyl 4-(2,2-dimethyl-4-oxo-4H-1,3-dioxin-6-yl)-3-oxobutanoate

Conditions

Conditions	Yield
In toluene at 55℃; Inert atmosphere; Schlenk technique;	99%
In toluene at 55℃; for 4h; regioselective reaction;	4.33 g

3-Methyl-2-buten-1-ol Chemical Properties

Molecular Structure of 3-Methyl-2-buten-1-ol (CAS No.556-82-1):

Molecular Formula: C₅H₁₀O
Molecular Weight: 86.13
IUPAC Name: 3-Methylbut-2-en-1-ol
CAS No: 556-82-1
EINECS: 209-141-4
H bond acceptors: 1
H bond donors: 1
Freely Rotating Bonds: 2
Polar Surface Area: 9.23 Å²
Index of Refraction: 1.435
Molar Refractivity: 26.64 cm³
Molar Volume: 101.9 cm³
Surface Tension: 26.4 dyne/cm
Density: 0.844 g/cm³
Flash Point: 43.3 °C
Enthalpy of Vaporization: 44.12 kJ/mol
Boiling Point: 141.5 °C at 760 mmHg
Vapour Pressure: 2.38 mmHg at 25°C
Refractive Index: 1.442-1.444
Water Solubility: 170 g/L (20 ºC)
Storage Temp.: Flammables area
Classification Code: Skin/Eye Irritant

3-Methyl-2-buten-1-ol Uses

3-Methyl-2-buten-1-ol (CAS No.556-82-1) is used occasionally in perfumery.It occurs naturally in citrus fruits, cranberry, bilberry, currants, grapes, raspberry, blackberry, tomato, white bread, hop oil, coffee, arctic bramble, cloudberry and passion fruit.

3-Methyl-2-buten-1-ol Production

3-Methyl-2-buten-1-ol (CAS No.556-82-1) is produced industrially by the reaction of formaldehyde with isobutene, followed by the isomerization of the resulting isoprenol (3-methyl-3-buten-1-ol).

3-Methyl-2-buten-1-ol Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rabbit	LD50	skin	3900mg/kg (3900mg/kg)		Food and Cosmetics Toxicology. Vol. 17, Pg. 895, 1979.
rat	LD50	oral	810mg/kg (810mg/kg)		Food and Cosmetics Toxicology. Vol. 17, Pg. 895, 1979.

3-Methyl-2-buten-1-ol Consensus Reports

3-Methyl-2-buten-1-ol (CAS No.556-82-1) is reported in EPA TSCA Inventory.

3-Methyl-2-buten-1-ol Safety Profile

Safety Information of 3-Methyl-2-buten-1-ol (CAS No.556-82-1):
Hazard Codes: Harmful Xn
Risk Statements: 10-22-36/37/38-38-21/22
R10:Flammable.
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
R38:Irritating to skin.
R21/22:Harmful in contact with skin and if swallowed.
Safety Statements: 26-36-37-23-16
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S37:Wear suitable gloves.
S23:Do not breathe vapour.
S16:Keep away from sources of ignition.
RIDADR: UN 1987 3/PG 3
WGK Germany: 1
RTECS: EM9472500
HazardClass: 3
PackingGroup: III
HS Code: 29052990

3-Methyl-2-buten-1-ol Specification

3-Methyl-2-buten-1-ol (CAS No.556-82-1), it also can be called 3,3-Dimethylallyl alcohol ; Prenyl alcohol ; 2-Buten-1-ol, 3-methyl- ; 2-Methyl-2-buten-4-ol ; 3-Methylbut-2-en-1-ol . It is clear colourless to very slightly yellow liquid. 3-Methyl-2-buten-1-ol (CAS No.556-82-1) is a natural alcohol. It is one of the most simple terpenes. It is a clear colorless oil that is reasonably soluble in water and miscible with most common organic solvents.

Product Name

3-Methyl-2-buten-1-ol

Synthetic route

3-Methyl-2-buten-1-ol Chemical Properties

3-Methyl-2-buten-1-ol Uses

3-Methyl-2-buten-1-ol Production

3-Methyl-2-buten-1-ol Toxicity Data With Reference

3-Methyl-2-buten-1-ol Consensus Reports

3-Methyl-2-buten-1-ol Safety Profile

3-Methyl-2-buten-1-ol Specification

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