Product Name

  • Name

    3-Methoxybenzenethiol

  • EINECS 239-617-7
  • CAS No. 15570-12-4
  • Article Data26
  • CAS DataBase
  • Density 1.112 g/cm3
  • Solubility Not miscible or difficult to mix in water. Soluble in methanol, benzene, hexane, toluene and dichloromethane.
  • Melting Point 264.4-268.3 °C (decomp)
  • Formula C7H8OS
  • Boiling Point 223.5 °C at 760 mmHg
  • Molecular Weight 140.206
  • Flash Point 96.1 °C
  • Transport Information UN 2810 6.1/PG 3
  • Appearance clear colorless to light yellow liquid
  • Safety 26-36/37-37/39
  • Risk Codes 20/21/22-36/37/38-22
  • Molecular Structure Molecular Structure of 15570-12-4 (3-Methoxybenzenethiol)
  • Hazard Symbols IrritantXi,HarmfulXn
  • Synonyms Benzenethiol,m-methoxy- (6CI,7CI,8CI);(m-Methoxyphenyl)thiol;3-Mercaptoanisole;3-Methoxythiophenol;m-Methoxybenzenethiol;m-Methoxythiophenol;
  • PSA 48.03000
  • LogP 1.98390

Synthetic route

3-methoxy-1-iodobenzene
766-85-8

3-methoxy-1-iodobenzene

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
Stage #1: 3-methoxy-1-iodobenzene With copper(l) iodide; potassium carbonate; sulfur In N,N-dimethyl-formamide at 90℃; for 12h; Inert atmosphere;
Stage #2: With sodium tetrahydroborate In N,N-dimethyl-formamide at 40℃; Inert atmosphere; Cooling with ice;
89%
With sodiumsulfide nonahydrate; copper; ethane-1,2-dithiol In dimethyl sulfoxide at 100℃; for 20h; Inert atmosphere; Green chemistry;89%
With copper(l) iodide; thiourea; L-proline; sodium t-butanolate In dimethyl sulfoxide at 90℃; for 24h; Inert atmosphere;85%
1-methoxy-3-methylsulfanyl-benzene
2388-74-1

1-methoxy-3-methylsulfanyl-benzene

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydride; diethylamine In xylene for 6h; Heating;88%
m-Anisidine
536-90-3

m-Anisidine

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
und ueber mehrere Stufen.Diazotization;
With hydrogenchloride; sodium nitrite Diazotization.man traegt in eine waessr. Loesung von xanthogensaurem Kalium bei 85-90grad ein und verseift den entstandenen Ester durch Kochen mit alkoh. Kalilauge;
(i) aq. NaNO2, aq. HCl, (ii) potassium ethylxanthate, (iii) KOEt, EtOH; Multistep reaction;
methoxybenzene
100-66-3

methoxybenzene

A

4-Methoxybenzenethiol
696-63-9

4-Methoxybenzenethiol

B

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
With disulfur dichloride; carbon disulfide; aluminium amalgam Destillieren des Reaktionsprodukts unter wenig vermindertem Druck;
1-methoxy-3-methylsulfanyl-benzene
2388-74-1

1-methoxy-3-methylsulfanyl-benzene

A

3-methylsulfanylphenol
3463-03-4

3-methylsulfanylphenol

B

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
With hydrogenchloride; sodium isopropanethiolate 1)sodium isopropanethiolate,HMPA,120 degC,2.5 h 2)hydrochloric acid; Yield given. Multistep reaction. Yields of byproduct given;
[Dimethylamino-(3-methoxy-phenylsulfanyl)-methylene]-dimethyl-ammonium; iodide

[Dimethylamino-(3-methoxy-phenylsulfanyl)-methylene]-dimethyl-ammonium; iodide

A

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

B

tetramethylurea
632-22-4

tetramethylurea

Conditions
ConditionsYield
at 20℃; Rate constant; pH=11;
[(3-methoxyphenyl)sulfanyl]acetic acid
3996-32-5

[(3-methoxyphenyl)sulfanyl]acetic acid

A

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

B

Glyoxilic acid
298-12-4

Glyoxilic acid

Conditions
ConditionsYield
With perchloric acid; sodium perborate; acetic acid at 24.9℃; Rate constant; Thermodynamic data; Mechanism; var. temp., ΔH(excit.), ΔS(excit.);
Ethyl-3-methoxyphenyl-disulfid
55975-74-1

Ethyl-3-methoxyphenyl-disulfid

A

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

B

ethanethiol
75-08-1

ethanethiol

Conditions
ConditionsYield
With triphenylphosphine In 1,4-dioxane; water at 30℃; Rate constant;
S-(3-methoxyphenyl) dimethylcarbamothioate
50667-88-4

S-(3-methoxyphenyl) dimethylcarbamothioate

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
With potassium hydroxide In methanol Heating;
With sodium hydroxide In methanol
(3S,3aR,4S,6aR,9S,9aR,9bR)-4-Hydroxy-3-(3-methoxy-phenylsulfanylmethyl)-9-methyl-6-methylene-octahydro-azuleno[4,5-b]furan-2,8-dione
248584-43-2

(3S,3aR,4S,6aR,9S,9aR,9bR)-4-Hydroxy-3-(3-methoxy-phenylsulfanylmethyl)-9-methyl-6-methylene-octahydro-azuleno[4,5-b]furan-2,8-dione

A

grosheimin
22489-66-3

grosheimin

B

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
With phosphate buffer In methanol at 37℃; pH=7.4; Kinetics; Hydrolysis;
[(3-methoxyphenyl)sulfanyl]acetic acid
3996-32-5

[(3-methoxyphenyl)sulfanyl]acetic acid

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
With perchloric acid; pyridinium chlorochromate In water; acetic acid at 24.85 - 44.85℃; Kinetics; Oxidation;
carbon disulfide
75-15-0

carbon disulfide

methoxybenzene
100-66-3

methoxybenzene

disulfur dichloride

disulfur dichloride

amalgamated aluminium

amalgamated aluminium

A

4-Methoxybenzenethiol
696-63-9

4-Methoxybenzenethiol

B

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
Destillation des entstandenen Oels unter wenig vermindertem Druck;
chloride of/the/ m-anisolesulfonic acid

chloride of/the/ m-anisolesulfonic acid

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
With sulfuric acid; zinc
m-anisole-sulfonic acid chloride

m-anisole-sulfonic acid chloride

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
With ethanol; zinc
hydrogenchloride
7647-01-0

hydrogenchloride

3-Methoxybenzenesulfonyl chloride
10130-74-2

3-Methoxybenzenesulfonyl chloride

zinc

zinc

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

O-methylresorcine
150-19-6

O-methylresorcine

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: (i) NaH, DMF, (ii) /BRN= 635823/
2: 280 °C
3: aq. NaOH / methanol
View Scheme
Multi-step reaction with 3 steps
1: (i) NaH, DMF, (ii) /BRN= 635823/
2: 270 °C
3: KOH / methanol / Heating
View Scheme
O-(3-methoxyphenyl) N,N-dimethylcarbamothioate
50667-83-9

O-(3-methoxyphenyl) N,N-dimethylcarbamothioate

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 280 °C
2: aq. NaOH / methanol
View Scheme
Multi-step reaction with 2 steps
1: 270 °C
2: KOH / methanol / Heating
View Scheme
((4-methoxy-2-(naphthalen-2-yloxy)phenyl)methylene)bis((3-methoxyphenyl)sulfane)
1221001-36-0

((4-methoxy-2-(naphthalen-2-yloxy)phenyl)methylene)bis((3-methoxyphenyl)sulfane)

A

9-methoxy-12-(3-methoxyphenylthio)-12H-benzo[a]xanthene
1221001-41-7

9-methoxy-12-(3-methoxyphenylthio)-12H-benzo[a]xanthene

B

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
With scandium tris(trifluoromethanesulfonate) In dichloromethane at 20℃; Friedel Crafts reaction;
sodium 3-methoxyphenylsulfanesulfonate
1561023-51-5

sodium 3-methoxyphenylsulfanesulfonate

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
With nickel(II) fluoride; triethoxyphenylsilane; palladium diacetate; trifluoroacetic acid In N,N-dimethyl acetamide at 100℃; Schlenk technique; Inert atmosphere;
C12H17NO2S

C12H17NO2S

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Conditions
ConditionsYield
With sodium hydroxide In diphenylether at 80 - 120℃; for 8h; Flow reactor; Large scale;921.3 g
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Bromoacetaldehyde diethyl acetal
2032-35-1

Bromoacetaldehyde diethyl acetal

1-[(2,2-diethoxyethyl)sulfanyl]-3-methoxybenzene
96803-85-9

1-[(2,2-diethoxyethyl)sulfanyl]-3-methoxybenzene

Conditions
ConditionsYield
Stage #1: 3-methoxybenzenethiol With potassium carbonate In acetonitrile at 20℃;
Stage #2: Bromoacetaldehyde diethyl acetal In acetonitrile for 15h;
100%
With potassium carbonate In acetone at 20℃; for 3h;100%
With potassium carbonate In acetone at 20℃; for 3h;100%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

methyl iodide
74-88-4

methyl iodide

1-methoxy-3-methylsulfanyl-benzene
2388-74-1

1-methoxy-3-methylsulfanyl-benzene

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.5h;100%
With sodium hydride In N,N-dimethyl-formamide 1.) 0 deg C, 15 min, 2.) room temperature, 45 min;90%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In benzene for 48h; Substitution;
5-bromo-3-(2-bromo-4-fluorophenoxy)picolinonitrile
1065609-78-0

5-bromo-3-(2-bromo-4-fluorophenoxy)picolinonitrile

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

5-bromo-3-(2-bromo-4-fluorophenoxy)picolinonitrile

5-bromo-3-(2-bromo-4-fluorophenoxy)picolinonitrile

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;100%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

4,5-dibromothiophene-2-carboxaldehyde
38071-22-6

4,5-dibromothiophene-2-carboxaldehyde

4-bromo-5-[(3-methoxyphenyl)thio]thiophene-2-carbaldehyde
1138032-94-6

4-bromo-5-[(3-methoxyphenyl)thio]thiophene-2-carbaldehyde

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;100%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2-[(3-methoxyphenyl)sulfanyl]ethyl phenyl sulfone
1308834-07-2

2-[(3-methoxyphenyl)sulfanyl]ethyl phenyl sulfone

Conditions
ConditionsYield
With potassium carbonate In dichloromethane at 20℃; for 20h; Inert atmosphere;100%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

acetic anhydride
108-24-7

acetic anhydride

S-3-methoxyphenyl ethanethioate

S-3-methoxyphenyl ethanethioate

Conditions
ConditionsYield
Stage #1: 3-methoxybenzenethiol; acetic anhydride With triethylamine In dichloromethane at 20℃; for 3h;
Stage #2: With hydrogenchloride In dichloromethane; water
100%
4-butanolide
96-48-0

4-butanolide

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

4-((3-methoxyphenyl)thio)butanoic acid sodium salt

4-((3-methoxyphenyl)thio)butanoic acid sodium salt

Conditions
ConditionsYield
With ethanol; sodium for 24h; Inert atmosphere; Reflux;100%
With sodium In ethanol for 24h; Inert atmosphere; Reflux;100%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

(2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
206193-17-1

(2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

C19H17F3N2O3S

C19H17F3N2O3S

Conditions
ConditionsYield
Stage #1: 3-methoxybenzenethiol With sodium hydride In tetrahydrofuran; mineral oil
Stage #2: (2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide In tetrahydrofuran; mineral oil at 20℃; for 20h;
100%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

bis(3-methoxyphenyl)disulfide
59014-89-0

bis(3-methoxyphenyl)disulfide

Conditions
ConditionsYield
1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione In chloroform at 20℃; for 0.0166667h;99.6%
With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione In chloroform at 20℃; for 1h; Inert atmosphere;97%
With titanium(IV) oxide; oxygen In acetonitrile under 750.075 Torr; for 0.416667h; Irradiation;96%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2-fluorobenzonitrile
394-47-8

2-fluorobenzonitrile

2-((3-methoxyphenyl)thio)benzonitrile

2-((3-methoxyphenyl)thio)benzonitrile

Conditions
ConditionsYield
With potassium fluoride on basic alumina; 18-crown-6 ether In acetonitrile for 18h; Heating;99%
With potassium fluoride on basic alumina; 18-crown-6 ether In acetonitrile for 18h; Heating;99%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

methyl 2-(bromomethyl)-6-nitrobenzoate
61940-21-4

methyl 2-(bromomethyl)-6-nitrobenzoate

methyl 2-(3-methoxyphenylthiomethyl)-6-nitrobenzoate

methyl 2-(3-methoxyphenylthiomethyl)-6-nitrobenzoate

Conditions
ConditionsYield
With sodium bicarbonate; sodium chloride; triethylamine In dichloromethane99%
(1H-1,2,3-benzotriazol-1-yl)(2,3-dihydro-1H-indol-1-yl)methanethione
865075-55-4

(1H-1,2,3-benzotriazol-1-yl)(2,3-dihydro-1H-indol-1-yl)methanethione

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2,3-dihydroindole-1-carbodithioic acid 3-methoxyphenyl ester

2,3-dihydroindole-1-carbodithioic acid 3-methoxyphenyl ester

Conditions
ConditionsYield
With sodium hydride In dichloromethane for 18h;99%
ethyl (2-chloroaceto)acetate
638-07-3

ethyl (2-chloroaceto)acetate

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

3-methoxybenzenethiol
16768-98-2

3-methoxybenzenethiol

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 0 - 20℃; for 2h;99%
With potassium hydroxide In methanol at 20℃; for 6h;
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 20℃; for 2.16667h;
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

5-bromoacetyl-2,4-dimethylthiazole hydrobromide
76007-16-4

5-bromoacetyl-2,4-dimethylthiazole hydrobromide

1-(2,4-dimethylthiazol-5-yl)-2-(3-methoxyphenylsulfanyl) ethanone
374754-18-4

1-(2,4-dimethylthiazol-5-yl)-2-(3-methoxyphenylsulfanyl) ethanone

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water99%
2-chloro-3-(phenylamino)naphthalene-1,4-dione
1090-16-0

2-chloro-3-(phenylamino)naphthalene-1,4-dione

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2-(3-methoxyphenylthio)-3-(phenylamino)naphthalene-1,4-dione
1171120-72-1

2-(3-methoxyphenylthio)-3-(phenylamino)naphthalene-1,4-dione

Conditions
ConditionsYield
With triethylamine In methanol at 70℃; for 4h;99%
Stage #1: 3-methoxybenzenethiol With triethylamine In water for 0.0833333h; Green chemistry;
Stage #2: 2-chloro-3-(phenylamino)naphthalene-1,4-dione In water at 65℃; Green chemistry;
99%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

4-bromo-8-nitroquinolin-2(1H)-one

4-bromo-8-nitroquinolin-2(1H)-one

4-(3-methoxyphenylthio)-8-nitroquinolin-2(1H)-one

4-(3-methoxyphenylthio)-8-nitroquinolin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 3-methoxybenzenethiol With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.5h; Inert atmosphere;
Stage #2: 4-bromo-8-nitroquinolin-2(1H)-one In N,N-dimethyl-formamide at 20℃; for 2h; Inert atmosphere;
99%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

tert-butyl alcohol
75-65-0

tert-butyl alcohol

tert-butyl 3-methoxyphenyl sulfoxide
49833-47-8

tert-butyl 3-methoxyphenyl sulfoxide

Conditions
ConditionsYield
Stage #1: 3-methoxybenzenethiol; tert-butyl alcohol With perchloric acid; acetic anhydride; acetic acid at 20℃; for 24h; Cooling with ice;
Stage #2: With dihydrogen peroxide at 0 - 20℃; for 8h;
99%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

Diphenylphosphine oxide
4559-70-0

Diphenylphosphine oxide

diphenylthiophosphinic acid-S-3-methoxyphenyl ester

diphenylthiophosphinic acid-S-3-methoxyphenyl ester

Conditions
ConditionsYield
With tert-Butyl peroxybenzoate; potassium iodide In dimethyl sulfoxide at 20℃; for 8h;99%
With oxygen; rose bengal In N,N-dimethyl-formamide at 20℃; for 12h; Schlenk technique; Inert atmosphere; Irradiation;91%
With sodium carbonate In N,N-dimethyl-formamide at 20℃; for 3h;77%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2,2,6-trimethyl-4-phenyl-1,4-diazabicyclo[4.1.0]heptan-5-one

2,2,6-trimethyl-4-phenyl-1,4-diazabicyclo[4.1.0]heptan-5-one

3-((3-methoxyphenylthio)methyl)-3,5,5-trimethyl-1-phenylpiperazin-2-one

3-((3-methoxyphenylthio)methyl)-3,5,5-trimethyl-1-phenylpiperazin-2-one

Conditions
ConditionsYield
With tris(pentafluorophenyl)borate In acetonitrile at 65℃; for 18h; Inert atmosphere;99%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

benzenesufonyl hydrazide
80-17-1

benzenesufonyl hydrazide

S-(3-methoxyphenyl) benzenesulfonothioate

S-(3-methoxyphenyl) benzenesulfonothioate

Conditions
ConditionsYield
With tert.-butylhydroperoxide; sodium iodide In acetonitrile at 20℃; for 12h;99%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

tert-butyl (2-oxo-1-propylindolin-3-ylidene)carbamate

tert-butyl (2-oxo-1-propylindolin-3-ylidene)carbamate

tert-butyl (3-((3-methoxyphenyl)thio)-2-oxo-1-propylindolin-3-yl)carbamate

tert-butyl (3-((3-methoxyphenyl)thio)-2-oxo-1-propylindolin-3-yl)carbamate

Conditions
ConditionsYield
With C12H15CoN2O6(1-)*K(1+) In dichloromethane at 20℃; for 0.0833333h; Schlenk technique; Green chemistry;99%
1-(4-(4-bromobenzoyl)piperidin-1-yl)ethanone
66309-71-5

1-(4-(4-bromobenzoyl)piperidin-1-yl)ethanone

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

1-(4-(4-((3-methoxyphenyl)thio)benzoyl)piperidin-1-yl)ethanone

1-(4-(4-((3-methoxyphenyl)thio)benzoyl)piperidin-1-yl)ethanone

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In toluene at 120℃; for 24h; Sealed tube; Inert atmosphere;99%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2-fluoro-6-[(4-methylphenyl)sulfanyl]benzonitrile
175204-11-2

2-fluoro-6-[(4-methylphenyl)sulfanyl]benzonitrile

2-(3-Methoxy-phenylsulfanyl)-6-p-tolylsulfanyl-benzonitrile

2-(3-Methoxy-phenylsulfanyl)-6-p-tolylsulfanyl-benzonitrile

Conditions
ConditionsYield
With potassium fluoride on basic alumina; 18-crown-6 ether In acetonitrile for 18h; Heating;98%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2-fluoro-6-[(4-methylthio)phenoxy]benzonitrile

2-fluoro-6-[(4-methylthio)phenoxy]benzonitrile

2-(3-Methoxy-phenylsulfanyl)-6-(4-methylsulfanyl-phenoxy)-benzonitrile

2-(3-Methoxy-phenylsulfanyl)-6-(4-methylsulfanyl-phenoxy)-benzonitrile

Conditions
ConditionsYield
With potassium fluoride on basic alumina; 18-crown-6 ether In acetonitrile for 18h; Heating;98%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2,6 dichloropurine
5451-40-1

2,6 dichloropurine

2-chloro-6-[(3-methoxyphenyl)thio]purine

2-chloro-6-[(3-methoxyphenyl)thio]purine

Conditions
ConditionsYield
With potassium tert-butylate In isopropyl alcohol at 50℃;98%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

5-(ethoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione
15568-86-2

5-(ethoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione

5-(3-methoxy-phenylsulfanylmethylene)-2,2-dimethyl-[1,3]dioxane-4,6-dione

5-(3-methoxy-phenylsulfanylmethylene)-2,2-dimethyl-[1,3]dioxane-4,6-dione

Conditions
ConditionsYield
With 1-butyl-3-methylimidazolium Tetrafluoroborate In ethyl acetate for 0.1h; microwave irradiation;98%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2-(4-fluorophenyl)-6-iodoimidazo[1,2-a]pyridine
478040-44-7

2-(4-fluorophenyl)-6-iodoimidazo[1,2-a]pyridine

2-(4-fluorophenyl)-6-(3-methoxyphenylsulfanyl)imidazo[1,2-a]pyridine

2-(4-fluorophenyl)-6-(3-methoxyphenylsulfanyl)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate; ethylene glycol In isopropyl alcohol at 80℃; for 20h;98%
2-bromo-pyridine
109-04-6

2-bromo-pyridine

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2-[(3-methoxyphenyl)thio]pyridine

2-[(3-methoxyphenyl)thio]pyridine

Conditions
ConditionsYield
Stage #1: 2-bromo-pyridine With 1,2,3-Benzotriazole; copper(l) iodide In dimethyl sulfoxide for 0.166667h;
Stage #2: 3-methoxybenzenethiol With potassium tert-butylate In dimethyl sulfoxide at 100℃; Further stages.;
98%
With potassium carbonate In dimethyl sulfoxide at 110℃; for 18h; Inert atmosphere;82%
With copper(l) iodide; 1-Hydroxymethyl-1H-benzotriazole; potassium tert-butylate In dimethyl sulfoxide at 80℃;71%
With potassium carbonate In N,N-dimethyl-formamide at 110℃; for 20h;
With potassium carbonate In N,N-dimethyl-formamide at 110℃; for 20h;
ethyl 4,7-dichloro-6-fluoroquinoline-3-carboxylate

ethyl 4,7-dichloro-6-fluoroquinoline-3-carboxylate

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

C19H15NO3SClF

C19H15NO3SClF

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 25℃;98%
Stage #1: ethyl 4,7-dichloro-6-fluoroquinoline-3-carboxylate; 3-methoxybenzenethiol In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: With potassium carbonate In N,N-dimethyl-formamide at 0 - 10℃; for 1h;
60%
tert-butyl {[5-bromo-4-(2-fluoropyridin-3-yl)-1,3-thiazol-2-yl]methyl}methylcarbamate
1138033-70-1

tert-butyl {[5-bromo-4-(2-fluoropyridin-3-yl)-1,3-thiazol-2-yl]methyl}methylcarbamate

3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

tert-butyl ({4-(2-fluoropyridin-3-yl)-5-[(3-methoxyphenyl)thio]-1,3-thiazol-2-yl}methyl)methylcarbamate
1138033-81-4

tert-butyl ({4-(2-fluoropyridin-3-yl)-5-[(3-methoxyphenyl)thio]-1,3-thiazol-2-yl}methyl)methylcarbamate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In toluene at 105℃; for 12h;98%

3-methoxybenzenethiol Chemical Properties

Molecular Structure of 3-methoxybenzenethiol (CAS NO.15570-12-4):

IUPAC Name: 3-methoxybenzenethiol 
Empirical Formula: C7H8OS
Molecular Weight: 140.2028
H bond acceptors: 1
H bond donors: 0
Freely Rotating Bonds: 2
Polar Surface Area: 34.53Å2
Index of Refraction: 1.565
Molar Refractivity: 41.1 cm3
Molar Volume: 126 cm3
Surface Tension: 37.7 dyne/cm
Density: 1.112 g/cm3
Flash Point: 96.1 °C
Enthalpy of Vaporization: 44.12 kJ/mol
Boiling Point: 223.5 °C at 760 mmHg
Vapour Pressure: 0.143 mmHg at 25°C
EINECS: 239-617-7 
Sensitive: Stench
BRN: 2041496
InChI
InChI=1/C7H8OS/c1-8-6-3-2-4-7(9)5-6/h2-5,9H,1H3
Smiles
c1c(S)cccc1OC
Product Categories: Thiol; Sulphur Derivatives; Phenol&Thiophenol&Mercaptan; Phenoles and thiophenoles; API intermediates; Miscellaneous

3-methoxybenzenethiol Safety Profile

Hazard Codes: HarmfulXn,IrritantXi
Risk Statements: 20/21/22-36/37/38-22 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R22:Harmful if swallowed.
Safety Statements: 26-36/37-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37:Wear suitable protective clothing and gloves. 
S37/39:Wear suitable gloves and eye/face protection.
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 3
F: 13
Hazard Note: Harmful/Stench
HS Code: 29309070

3-methoxybenzenethiol Specification

  3-methoxybenzenethiol , with CAS number of 15570-12-4, can be called benzenethiol, 3-methoxy- ; meta-Methoxybenzenethiol ; 3-Mercaptoanisole ; 3-Methoxy Thiophenol ; 3-Methoxythiophenol . It is a clear colorless to light yellow liquid.

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