Product Name

  • Name

    4-ACETOXYBENZALDEHYDE

  • EINECS 212-898-3
  • CAS No. 878-00-2
  • Article Data117
  • CAS DataBase
  • Density 1.168
  • Solubility
  • Melting Point 213 °C
  • Formula C9H8 O3
  • Boiling Point 275 ºC at 760 mmHg
  • Molecular Weight 164.161
  • Flash Point 113 ºC
  • Transport Information
  • Appearance Clear colorless to pale yellow liquid
  • Safety 36/37/38
  • Risk Codes R36/37/38   
  • Molecular Structure Molecular Structure of 878-00-2 (4-ACETOXYBENZALDEHYDE)
  • Hazard Symbols
  • Synonyms Benzaldehyde,p-hydroxy-, acetate (6CI,7CI,8CI); 4-(Acetyloxy)benzaldehyde;4-Acetoxybenzaldehyde; 4-Formylphenyl acetate; Acetic acid 4-formylphenylester; NSC 40537; p-Acetoxybenzaldehyde; p-Hydroxybenzaldehyde acetate
  • PSA 43.37000
  • LogP 1.42440

Synthetic route

acetic anhydride
108-24-7

acetic anhydride

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With pyridine; aluminum oxide at 100 - 102℃; for 4h; microwave irradiation;100%
With pyridine at 20℃; for 16h;100%
With potassium carbonate In dichloromethane at 20℃; for 2h; Time;96.73%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

acetyl chloride
75-36-5

acetyl chloride

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 0 - 20℃; Inert atmosphere;100%
With triethylamine In ethyl acetate at 0 - 20℃; for 5h; Inert atmosphere;100%
With triethylamine In dichloromethane at 0℃; for 0.5h; Inert atmosphere;99%
acetyloxy(4-acetyloxyphenyl)methyl acetate
7143-16-0

acetyloxy(4-acetyloxyphenyl)methyl acetate

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With aluminum oxide at 35℃; for 0.00833333h; microwave irradiation;98%
With cerium(IV) ammonium nitrate supported on silica In dichloromethane for 0.25h;98%
With N,N'-dibromo-N,N'-(1,2-ethanediyl)bis(p-toluenesulfonamide); water at 20℃; for 0.025h; solid-phase reaction;98%
2-<4-(acetoxy)phenyl>-1,3-dithiolane
150372-43-3

2-<4-(acetoxy)phenyl>-1,3-dithiolane

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With bismuth(III) nitrate; water In benzene at 20℃; for 4h;98%
Stage #1: 2-<4-(acetoxy)phenyl>-1,3-dithiolane In ethanol at 20℃;
Stage #2: With water In ethanol at 20℃;
93%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

2-acetyl-4,5-dichloropyridazin-3(2H)-one
155164-63-9

2-acetyl-4,5-dichloropyridazin-3(2H)-one

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
Stage #1: 4-hydroxy-benzaldehyde With aluminum (III) chloride In tetrahydrofuran for 0.0166667h;
Stage #2: 2-acetyl-4,5-dichloropyridazin-3(2H)-one In tetrahydrofuran at 20℃; for 0.5h;
98%
In neat (no solvent) at 100℃; for 0.0833333h; Sealed tube; Green chemistry;97%
In tetrahydrofuran at 150℃; under 10336 Torr; for 0.0833333h; Microwave irradiation;90%
4-(1,3-oxathiolan-2-yl)phenyl acetate

4-(1,3-oxathiolan-2-yl)phenyl acetate

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
Stage #1: 4-(1,3-oxathiolan-2-yl)phenyl acetate In ethanol at 20℃;
Stage #2: With water In ethanol at 20℃;
97%
With eosin Y disodium salt In acetonitrile at 20℃; for 3h; Irradiation;91%
With cerium(III) chloride; sodium iodide In acetonitrile for 3.5h; Heating;85%
With ammonium bromide; dihydrogen peroxide; vanadia In dichloromethane at 0 - 5℃; for 1h;84%
Stage #1: 4-(1,3-oxathiolan-2-yl)phenyl acetate With acetyl chloride; sodium nitrite In dichloromethane at 0 - 5℃; for 0.166667h;
Stage #2: With water In dichloromethane at 0 - 5℃; for 0.25h;
82%
4-acetoxybenzyl alcohol
6309-46-2

4-acetoxybenzyl alcohol

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With laccase; 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt In tetrahydrofuran; water at 40℃; for 24h;92%
With pyridinium chlorochromate In dichloromethane at 20℃; for 4h;84%
With phosphoric acid In water; toluene at 25℃; under 760.051 Torr; for 24h; pH=3.4; Irradiation; Inert atmosphere; Sealed tube;84 %Spectr.
2-[4'-acetoxyphenyl]-1,3-dithiane
195054-29-6

2-[4'-acetoxyphenyl]-1,3-dithiane

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With bismuth(III) nitrate; water In benzene at 20℃; for 2h;92%
Stage #1: 2-[4'-acetoxyphenyl]-1,3-dithiane With acetyl chloride; sodium nitrite In dichloromethane at 0 - 5℃; for 0.25h;
Stage #2: With water In dichloromethane at 0 - 20℃; for 3.5h;
85%
1,1-diacetoxy-1-(2-acetoxyphenyl)methane
634-20-8

1,1-diacetoxy-1-(2-acetoxyphenyl)methane

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With sodium hydrogen sulfate; PEG-2000 at 70℃; for 0.3h;92%
4-(isopropylcarbamoyl)phenyl acetate

4-(isopropylcarbamoyl)phenyl acetate

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
Stage #1: 4-(isopropylcarbamoyl)phenyl acetate With 2-fluoropyridine; trifluoromethylsulfonic anhydride In dichloromethane at 0℃; for 0.333333h; Inert atmosphere;
Stage #2: With 1,1,3,3-Tetramethyldisiloxane In dichloromethane at 0 - 20℃; for 6.16667h; Inert atmosphere;
Stage #3: With hydrogenchloride In dichloromethane; water at 20℃; Inert atmosphere;
86%
formic acid
64-18-6

formic acid

4-acetoxyiodobenzene
33527-94-5

4-acetoxyiodobenzene

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With iodine; triethylamine; triphenylphosphine In toluene at 80℃; Inert atmosphere; Sealed tube;83%
acetic acid 4-dimethoxymethyl-phenyl ester
79721-01-0

acetic acid 4-dimethoxymethyl-phenyl ester

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With β‐cyclodextrin In methanol; water at 50℃; for 12h;82%
3-Acetoxy-1-(diacetoxymethyl)benzene
6339-75-9

3-Acetoxy-1-(diacetoxymethyl)benzene

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With zirconium sulfophenyl phosphonate In 1,4-dioxane at 50℃; for 5h;81%
p-acetoxystyrene
2628-16-2

p-acetoxystyrene

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With ozone; 1-[{4-(phenylazo)-phenyl}-azo]-2-naphthalenol In water; acetonitrile at 0℃;81%
With N-hydroxyphthalimide; oxygen; cobalt(II) diacetate tetrahydrate at 20℃; under 760.051 Torr; for 48h;65%
With 2,2'-azobis(isobutyronitrile); oxygen In nitromethane at 60℃; for 12h; Schlenk technique;63%
With sodium periodate; C23H24ClN4Ru(1+)*Br(1-) In water; acetone at 20℃; Catalytic behavior; Reagent/catalyst;41%
1-acetoxy-4-methylbenzene
140-39-6

1-acetoxy-4-methylbenzene

A

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

B

Acetic acid 4-nitrooxymethyl-phenyl ester
91735-04-5

Acetic acid 4-nitrooxymethyl-phenyl ester

Conditions
ConditionsYield
With ammonium cerium(IV) nitrate In acetonitrile at 40℃; for 2.5h; Irradiation;A n/a
B 80%
With ammonium cerium(IV) nitrate In acetonitrile at 40℃; for 2.5h; Mechanism; Irradiation;A n/a
B 80%
nickel(II) acetate tetrahydrate
6018-89-9

nickel(II) acetate tetrahydrate

N-tert-butoxycarbonyl-proline
15761-39-4

N-tert-butoxycarbonyl-proline

p-(iodophenyl)carboxaldehyde
15164-44-0

p-(iodophenyl)carboxaldehyde

A

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

B

1-(tert-butyl) 2-(4-formylphenyl)pyrrolidine-1,2-dicarboxylate

1-(tert-butyl) 2-(4-formylphenyl)pyrrolidine-1,2-dicarboxylate

Conditions
ConditionsYield
With N-isopropyl-N-tert-butylamine; 4,4'-di-tert-butyl-2,2'-bipyridine In dimethyl sulfoxide at 40℃; for 24h; Time; Irradiation; Sealed tube;A 12 %Spectr.
B 80%
acetic acid 4-(bis-ethylsulfanyl-methyl)-phenyl ester

acetic acid 4-(bis-ethylsulfanyl-methyl)-phenyl ester

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With dihydrogen peroxide; vanadia; ammonium bromide In dichloromethane; water at 0 - 5℃; for 1.5h;75%
With ammonium heptamolybdate; dihydrogen peroxide; ammonium bromide; perchloric acid In dichloromethane; water at 0 - 5℃; for 0.5h;75%
(4-acetoxyphenyl)acetic acid
38177-33-2

(4-acetoxyphenyl)acetic acid

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With mercury(II) fluoride; oxygen In acetonitrile at 25℃; for 24h; Irradiation;75%
C20H18O6

C20H18O6

A

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

B

3,4-diacetoxybenzaldehyde
67727-64-4

3,4-diacetoxybenzaldehyde

Conditions
ConditionsYield
With 1-hydroxy-pyrrolidine-2,5-dione; graphitic carbon nitride; oxygen In acetonitrile at 20℃; Inert atmosphere; Irradiation;A 57%
B 57%
4-bromophenyl acetate
1927-95-3

4-bromophenyl acetate

carbon monoxide
201230-82-2

carbon monoxide

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With N,N,N,N,-tetramethylethylenediamine; hydrogen; palladium diacetate; catacxium A In toluene at 80℃; for 64h; Inert atmosphere;49%
4-acetoxybenzyl bromide
52727-95-4

4-acetoxybenzyl bromide

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With pyridine N-oxide for 0.0111111h; Irradiation; with microwave irradiation;40%
With dimethyl sulfoxide
α,α-dibromo-p-methylphenol acetate

α,α-dibromo-p-methylphenol acetate

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With benzaldehyde dimethyl acetal; zinc(II) chloride In neat (no solvent) at 80℃; for 2h;30%
p-acetoxystyrene
2628-16-2

p-acetoxystyrene

A

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

B

2-azido-1-(4-acetoxyphenyl)ethanone

2-azido-1-(4-acetoxyphenyl)ethanone

Conditions
ConditionsYield
With trimethylsilylazide; copper(II) sulfate In acetonitrile at 20℃; for 9h; Reagent/catalyst; Green chemistry;A 27%
B n/a
diethyl ether
60-29-7

diethyl ether

acetic anhydride
108-24-7

acetic anhydride

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
aus dem Kaliumsalz des p-Oxy-benzaldehyds;
Ketene
463-51-4

Ketene

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Conditions
ConditionsYield
With acetone
Ketene
463-51-4

Ketene

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

acetone
67-64-1

acetone

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

1-acetoxy-4-methylbenzene
140-39-6

1-acetoxy-4-methylbenzene

A

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

B

p-acetoxybenzyl methyl ether
38177-36-5

p-acetoxybenzyl methyl ether

Conditions
ConditionsYield
With sulfuric acid; lithium perchlorate 1.) electrochemical anodic oxidation, AcOH, MeOH, 2.) RT, 3 h; Yield given. Multistep reaction. Yields of byproduct given;
With sulfuric acid; tetraethylammonium tosylate 1.) electrochemical anodic oxidation, AcOH, MeOH, 2.) RT, 3 h; Yield given. Multistep reaction. Yields of byproduct given;
3-nitrophenyl acetate
1523-06-4

3-nitrophenyl acetate

4-formylphenolate ion
18938-17-5

4-formylphenolate ion

A

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

B

3-nitrophenolate anion
16554-54-4

3-nitrophenolate anion

Conditions
ConditionsYield
In water at 25℃; Rate constant; ionic strength - 0.1 M KCl;
2-nitrophenyl acetate
610-69-5

2-nitrophenyl acetate

4-formylphenolate ion
18938-17-5

4-formylphenolate ion

A

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

B

2-Nitrophenolate ion
16554-53-3

2-Nitrophenolate ion

Conditions
ConditionsYield
In water at 25℃; Rate constant;
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

Conditions
ConditionsYield
With ammonium acetate In methanol at 20℃; for 3h;100%
With water; sodium acetate In ethanol for 5h; Reflux;98%
With aluminum oxide In neat (no solvent) at 75℃; for 0.05h; microwave irradiation;92%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

trimethylsilyl cyanide
7677-24-9

trimethylsilyl cyanide

C13H17NO3Si
118736-06-4

C13H17NO3Si

Conditions
ConditionsYield
With C32H39Br2MgN2(1-)*C16H32LiO4(1+) In chloroform-d1 at 20℃; for 3h; Inert atmosphere; Glovebox;99%
With C16H27ClN2Si In benzene at 20℃; for 6h; Inert atmosphere; Schlenk technique; Glovebox;60%
With 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R,2R)-2-(5-phenyl-1H-imidazol-1-yl)cyclohexyl)thiourea; benzoic acid In toluene at -30℃; for 16h; Inert atmosphere; enantioselective reaction;
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

acetic anhydride
108-24-7

acetic anhydride

acetyloxy(4-acetyloxyphenyl)methyl acetate
7143-16-0

acetyloxy(4-acetyloxyphenyl)methyl acetate

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In dichloromethane at 0 - 20℃; for 0.5h;98%
With bismuth(III) nitrate In acetonitrile at 20℃; for 16h;91%
With titanium tetrachloride In dichloromethane at 20℃; for 0.833333h;88%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

p-methylphenyl-1-thio-β-D-galactopyranoside
1152-39-2, 28244-98-6, 121523-95-3, 131488-68-1

p-methylphenyl-1-thio-β-D-galactopyranoside

4-methylphenyl 4,6-O-((4-acetoxyphenyl)methylene)-1-thio-β-D-galactopyranoside

4-methylphenyl 4,6-O-((4-acetoxyphenyl)methylene)-1-thio-β-D-galactopyranoside

Conditions
ConditionsYield
With vanadyl triflate In acetonitrile at 20℃; for 12h;98%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

1,3-dimethylbarbituric acid
769-42-6

1,3-dimethylbarbituric acid

5-(4'-acetoxybenzylidene)-1,3-dimethylbarbituric acid
110449-08-6

5-(4'-acetoxybenzylidene)-1,3-dimethylbarbituric acid

Conditions
ConditionsYield
In ethanol for 1h; Heating;97%
In ethanol Heating; Yield given;
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane
25015-63-8

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

4-(((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)oxy)methyl)phenyl acetate

4-(((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)oxy)methyl)phenyl acetate

Conditions
ConditionsYield
With C34H28N6Zn In toluene at 20℃; for 4h; Glovebox; Schlenk technique; chemoselective reaction;97%
With [Fe{N(SiMe3)2}2]2 In tetrahydrofuran at 20℃; for 4h; Inert atmosphere; Glovebox; Schlenk technique; chemoselective reaction;97 %Spectr.
With [{2-(AdN=CH)–C4H3NK(THF)}n] In toluene at 30℃; Inert atmosphere; Glovebox; Schlenk technique; chemoselective reaction;
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

trimethyl orthoformate
149-73-5

trimethyl orthoformate

acetic acid 4-dimethoxymethyl-phenyl ester
79721-01-0

acetic acid 4-dimethoxymethyl-phenyl ester

Conditions
ConditionsYield
With lithium tetrafluoroborate In methanol for 0.5h; Heating;96%
2-methyl-1H-indole
95-20-5

2-methyl-1H-indole

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

bis(2-methyl-3-indolyl)(4-acetoxyphenyl)methane
1229027-69-3

bis(2-methyl-3-indolyl)(4-acetoxyphenyl)methane

Conditions
ConditionsYield
In glycerol at 100℃; for 5h;96%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

4-O-acetylbenzaldehyde oxime
757965-23-4

4-O-acetylbenzaldehyde oxime

Conditions
ConditionsYield
With pyridine; hydroxylamine hydrochloride In methanol at 20℃; for 2.5h;96%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

4-Methoxyphenylacetic acid
104-01-8

4-Methoxyphenylacetic acid

(E)-3-(4-acetoxyphenyl)-2-(4-methoxyphenyl)acrylic acid

(E)-3-(4-acetoxyphenyl)-2-(4-methoxyphenyl)acrylic acid

Conditions
ConditionsYield
With acetic anhydride; triethylamine at 110℃; for 8h; Green chemistry;96%
With sodium methylate In methanol37%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

4-acetoxybenzaldehyde-α-d1

4-acetoxybenzaldehyde-α-d1

Conditions
ConditionsYield
With tetrakis(tetrabutylammonium)decatungstate(VI); 2,4,6-Triisopropylthiophenol; water-d2 In acetonitrile for 24h; Irradiation;96%
With sodium benzoate; (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; water-d2; triisopropylsilanethiol In ethyl acetate at 20℃; for 36h; Inert atmosphere; Irradiation;50%
With 1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydro-1H-imidazolium bromide; water-d2; sodium hydrogencarbonate In toluene at 60℃; for 12h;47%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

nitromethane
75-52-5

nitromethane

4-acetoxy-β-nitro-styrene
18984-24-2

4-acetoxy-β-nitro-styrene

Conditions
ConditionsYield
With aminopropylated nanosilica for 12h; Henry reaction; Reflux;95%
With potassium hydroxide at 0℃;
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

4-acetoxybenzyl alcohol
6309-46-2

4-acetoxybenzyl alcohol

Conditions
ConditionsYield
With sodium tetrahydroborate; phosphoric acid In methanol at -5℃;95%
With sodium tetrahydroborate In tetrahydrofuran at 20℃; for 5h;94%
With lithium aluminium tetrahydride In tetrahydrofuran for 0.5h; Cooling with ice;90%
indole
120-72-9

indole

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

4-(di(1H-indol-3-yl)methyl)phenyl acetate

4-(di(1H-indol-3-yl)methyl)phenyl acetate

Conditions
ConditionsYield
amberlyst-15 In dichloromethane at 20℃; for 2.5h;95%
With tetrachlorosilane for 0.0166667h; microwave irradiation;92%
With C22H18I2N4(2+)*2CF3O3S(1-) In acetonitrile at 70℃; for 48h;92%
With ionic liquid immobilized on silica In acetonitrile at 20℃; for 4h;64%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

Dimethylphenylsilane
766-77-8

Dimethylphenylsilane

acetic acid 4-(dimethyl-phenyl-silanoxymethyl)-phenyl ester

acetic acid 4-(dimethyl-phenyl-silanoxymethyl)-phenyl ester

Conditions
ConditionsYield
With iododioxobis(triphenylphosphine)rhenium(V) In benzene for 1h; Heating;95%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

p-methylphenyl 1-thio-β-D-glucopyranoside
1152-39-2

p-methylphenyl 1-thio-β-D-glucopyranoside

4-methylphenyl 4,6-O-((4-acetoxyphenyl)methylene)-1-thio-β-D-glucopyranoside

4-methylphenyl 4,6-O-((4-acetoxyphenyl)methylene)-1-thio-β-D-glucopyranoside

Conditions
ConditionsYield
With vanadyl triflate In acetonitrile at 20℃; for 8h;95%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

carbon tetrabromide
558-13-4

carbon tetrabromide

1,1-dibromo-2[4-acetoxyphenyl]ethylene

1,1-dibromo-2[4-acetoxyphenyl]ethylene

Conditions
ConditionsYield
With triphenylphosphine; zinc In dichloromethane at -5 - 20℃; for 48h; Inert atmosphere; Schlenk technique;95%
With triphenylphosphine In dichloromethane at 20℃; for 4h;28%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

(R)-5-bromo-2-(5-bromoindolin-2-yl)phenol
1585969-17-0

(R)-5-bromo-2-(5-bromoindolin-2-yl)phenol

4-((6S,12aR)-3,10-dibromo-12,12a-dihydro-6H-benzo[5,6][1,3]-oxazino[3,4-a]indol-6-yl)phenyl acetate

4-((6S,12aR)-3,10-dibromo-12,12a-dihydro-6H-benzo[5,6][1,3]-oxazino[3,4-a]indol-6-yl)phenyl acetate

Conditions
ConditionsYield
With trifluoroacetic acid In acetonitrile at 35℃; for 3h; Inert atmosphere; diastereoselective reaction;95%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

4-acetyloxy-benzoic acid
2345-34-8

4-acetyloxy-benzoic acid

Conditions
ConditionsYield
With dihydrogen peroxide at 20℃; for 0.5h;94%
With oxygen; C34H4F60NiO4 In toluene at 64℃; under 760 Torr; for 12h;74%
With oxygen; acetic anhydride; butyraldehyde; cobalt(II) chloride In acetonitrile Ambient temperature;62%
In water at 25℃; Rate constant; xanthine oxidase; also in aerosol OT/isooctane system;
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

(E)-4,4’-diacetoxystilbene
47241-75-8

(E)-4,4’-diacetoxystilbene

Conditions
ConditionsYield
With titanium(III) chloride; copper; zinc In tetrahydrofuran for 17h; Heating;94%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

O-phenylhydroxylamine
4846-21-3

O-phenylhydroxylamine

acetic acid 4-(phenoxyimino-methyl)-phenyl ester

acetic acid 4-(phenoxyimino-methyl)-phenyl ester

Conditions
ConditionsYield
In water; acetonitrile for 0.166667h;94%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

1-phenylpropadiene
2327-99-3

1-phenylpropadiene

dimethylphenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane
185990-03-8

dimethylphenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane

4-[(1SR,2SR)-3-(1,1-dimethyl-1-phenylsilyl)-1-hydroxy-2-phenyl-3-butenyl]phenyl acetate

4-[(1SR,2SR)-3-(1,1-dimethyl-1-phenylsilyl)-1-hydroxy-2-phenyl-3-butenyl]phenyl acetate

Conditions
ConditionsYield
With 3-iodo-2-methylcyclohexenone; bis(dibenzylideneacetone)-palladium(0) In ethyl acetate at 80℃; for 5h;93%
4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

benzyloxy-trimethylsilane
14642-79-6

benzyloxy-trimethylsilane

4-(benzyloxymethyl)phenyl acetate

4-(benzyloxymethyl)phenyl acetate

Conditions
ConditionsYield
With triethylsilane; iron(III) chloride In nitromethane at 20℃; for 0.166667h;93%
methanol
67-56-1

methanol

4-formylphenyl acetate
878-00-2

4-formylphenyl acetate

methyl 4-acetoxybenzoate
24262-66-6

methyl 4-acetoxybenzoate

Conditions
ConditionsYield
With [bis(acetoxy)iodo]benzene; sodium bromide at 20℃; for 2h;93%

4-Acetoxybenzaldehyde Chemical Properties

Product Name: Benzaldehyde,4-(acetyloxy)- (CAS NO.878-00-2)

Molecular Formula: C9H8O3
Molecular Weight: 164.16g/mol
Mol File: 878-00-2.mol
EINECS: 212-898-3
Appearance: Clear colorless to pale yellow liquid
Sensitive: Air Sensitive
Index of Refraction: 1.552 
Molar Refractivity: 44.34 cm3 
Molar Volume: 138.7 cm3  
Surface Tension: 42.3 dyne/cm 
Density: 1.183 g/cm3 
Flash Point: 119.4 °C 
Enthalpy of Vaporization: 51.35 kJ/mol 
Boiling Point: 275 °C at 760 mmHg 
Vapour Pressure: 0.00522 mmHg at 25°C
XLogP3-AA: 0.6
H-Bond Donor: 0
H-Bond Acceptor: 3
Structure Descriptors of Benzaldehyde,4-(acetyloxy)- (CAS NO.878-00-2):
  IUPAC Name: (4-formylphenyl) acetate
  Canonical SMILES: CC(=O)OC1=CC=C(C=C1)C=O
  InChI: InChI=1S/C9H8O3/c1-7(11)12-9-4-2-8(6-10)3-5-9/h2-6H,1H3 
InChIKey: SEVSMVUOKAMPDO-UHFFFAOYSA-N
Product Categories: Aromatic Aldehydes & Derivatives (substituted);Benzaldehyde (Building Blocks for Liquid Crystals); Building Blocks for Liquid Crystals; Functional Materials; Aromatic Building Blocks

4-Acetoxybenzaldehyde Safety Profile

Safety Information of Benzaldehyde,4-(acetyloxy)- (CAS NO.878-00-2):
Hazard Codes: XiIrritant
Risk Statements: 36/37/38  
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 3
TSCA: T
HazardClass: IRRITANT

4-Acetoxybenzaldehyde Specification

 Benzaldehyde,4-(acetyloxy)- , its CAS NO. is 878-00-2, the synonyms are 4-Acetoxybenzaldehyde ; Benzaldehyde, 4-(acetyloxy)- ; Benzaldehyde, p-hydroxy-, acetate ; p-Acetoxybenzaldehyde ; p-Hydroxybenzaldehyde acetate .

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