4-Methylsulfonylacetophenone supplier

Name
4-Methylsulphonylacetophenone
EINECS 233-672-0
CAS No. 10297-73-1
Article Data76
CAS DataBase
Density 1.218 g/cm³
Solubility
Melting Point 126-129 °C(lit.)
Formula C₉H₁₀O₃S
Boiling Point 385.4 °C at 760 mmHg
Molecular Weight 198.243
Flash Point 242 °C
Transport Information
Appearance White to slightly yellow cryst. powder or needles
Safety 24/25
Risk Codes
Molecular Structure
Hazard Symbols Xi
Synonyms Acetophenone,4'-(methylsulfonyl)- (6CI,7CI,8CI);1-(4-Methylsulfonylphenyl)ethanone;1-[4-(Methylsulfonyl)phenyl]ethan-1-one;4-(Methanesulfonyl)acetophenone;4-(Methylsulfonyl)propiophenone;4'-(Methylsulfonyl)acetophenone;Ethanone,1-[4-(methylsulfonyl)phenyl]-;p-Acetylphenyl methyl sulfone;p-Methylsulfonylacetophenone;
PSA 59.59000
LogP 2.37350

Synthetic route

: 1778-09-2
4-(Methylthio)acetophenone

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With MMPP In methanol; dichloromethane at 20℃; for 3h;	100%
With sulfuric acid; dihydrogen peroxide; acetic acid at 0 - 70℃; for 2h;	99%
With dihydrogen peroxide; Cu2H4O40Te2W8(12-)(x)H2O12Na(1+) In acetonitrile at 20℃; for 10h; Sealed tube;	98%

: 13329-40-3
4-Iodoacetophenone

: 20277-69-4
sodium methansulfinate

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With copper(l) iodide; N,N-dimethyl-N-benzyl-N-(2-methacryloyloxyethyl)ammonium bromide; caesium carbonate In chlorobenzene at 110℃; for 24h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;	94.9%
With potassium phosphate; copper(l) iodide; (2S,4R)-N-(2,6-dimethylphenyl)-4-hydroxypyrrolidine-2-carboxamide In dimethyl sulfoxide at 20℃; for 24h; Inert atmosphere;	83%
With copper(l) iodide; sodium L-prolinate In dimethyl sulfoxide at 80℃; for 24h;	80%
With copper(I) trifluoromethanesulfonate benzene; N,N`-dimethylethylenediamine In dimethyl sulfoxide at 110℃; for 20h;

: 1778-09-2
4-(Methylthio)acetophenone

A: 32361-73-2
1-(4-methansulfinylphenyl)ethanone

B: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In acetonitrile for 0.0833333h; cooling;	A 94% B 2%
With oxygen at 80℃; for 20h; chemoselective reaction;	A 67% B 9%
With oxygen; 4C24H20P(1+)2H(1+)V10O28(6-) In water; butanone at 30℃; under 760.051 Torr; for 2h; Irradiation; Schlenk technique;	A 65% B 11 %Chromat.

: 90610-42-7
1-(4-(methylsulfonyl)phenyl)ethan-1-one oxime

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With sodium nitrite In water; acetonitrile at 40℃; for 4.33333h;	89%

: 20277-69-4
sodium methansulfinate

: 99-90-1
para-bromoacetophenone

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With potassium phosphate; copper(l) iodide; (2S,4R)-N-(2,6-dimethylphenyl)-4-hydroxypyrrolidine-2-carboxamide In dimethyl sulfoxide at 90℃; for 24h; Inert atmosphere;	80%
With copper(l) iodide; sodium L-prolinate In dimethyl sulfoxide at 95℃; for 48h;	62%

: 1-(4-(methylsulfonyl)phenyl)-2-phenoxyethan-1-one

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With 2,6-bis[1-(2,6-dimethylphenylimino)ethyl]pyridine cobalt(II)dichloride; bis(pinacol)diborane; sodium t-butanolate In tetrahydrofuran; methanol at 65℃; for 3h; Schlenk technique; Inert atmosphere;	80%

: 110-05-4
di-tert-butyl peroxide

: 1-[4-(sodiosulfonyl)phenyl]ethan-1-one

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With water at 110℃; for 12h; Sealed tube; Green chemistry;	75%

: 20277-69-4
sodium methansulfinate

: 149104-90-5
4-acetylphenylboronic acid

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With copper diacetate; 4 Angstroem MS; potassium carbonate In dimethyl sulfoxide at 20 - 60℃; for 16h;	71%

: 25888-99-7
1-(4-(methylsulfonyl)phenyl)ethan-1-ol

A: 10297-73-1
4-(methanesulfonyl)acetophenone

B: 4052-30-6
4-methylsulfonylbenzoic acid

Conditions

Conditions	Yield
Stage #1: 1-(4-(methylsulfonyl)phenyl)ethan-1-ol With oxygen; sodium hydride In tetrahydrofuran at 0 - 20℃; for 16h; Stage #2: With hydrogenchloride In water	A 30% B 68%

: 13329-40-3
4-Iodoacetophenone

: 67-68-5
dimethyl sulfoxide

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With copper(I) oxide; potassium tert-butylate; oxygen; acetylacetone at 100℃; for 20h;	52%

: 616-38-6
carbonic acid dimethyl ester

: 149104-90-5
4-acetylphenylboronic acid

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With sodium metabisulfite; tetrabutylammomium bromide; palladium dichloride; tert-butyl XPhos In N,N-dimethyl-formamide at 120℃; for 12h; Inert atmosphere;	50%

: 917-64-6
methyl magnesium iodide

: 22821-76-7
4-(methylsulfonyl)benzonitrile

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With diethyl ether; benzene Erwaermen des Reaktionsgemisches mit wss. H2SO4;

: 40913-92-6
4-methylsulfonylbenzoyl chloride

: diethyl ethoxymagnesium malonate

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With benzene Erhitzen einer Loesung des Reaktionsprodukts in Benzol mit wss. HCl und Essigsaeure;

: 32361-73-2
1-(4-methansulfinylphenyl)ethanone

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With potassium chromite; sodium perchlorate; oxalic acid In acetic acid at 40℃; Rate constant;
With potassium bromate; sulfuric acid; mercury(II) diacetate In acetic acid at 35℃; Kinetics; Mechanism; Thermodynamic data; other temperatures, ΔH(excit.), ΔS(excit.);
With peroxomonophosphoric acid; sodium perchlorate In water; acetic acid at 35℃; Kinetics; Further Variations:; Temperatures;
With oxo(salen)chromium(V) perchlorate In acetonitrile at 24.85℃; Kinetics; Further Variations:; Reagents;

: 186581-53-3, 908094-01-9
diazomethane

: 5398-77-6
para-methanesulfonylbenzaldehyde

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
In diethyl ether

: 90844-21-6
(4-Acetyl-phenylsulfon)-essigsaeure

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
at 160 - 180℃;

1-<4-methylsulfanyl-phenyl>-ethanone-(1): 1-<4-methylsulfanyl-phenyl>-ethanone-(1)

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With dihydrogen peroxide; acetic acid at 100℃;

: 56-23-5
tetrachloromethane

: 101595-66-8
3-hydroxy-3-(4-methanesulfonyl-phenyl)-2-phenyl-butyric acid

aqueous propan-1-ol: aqueous propan-1-ol

A: 103-82-2
phenylacetic acid

B: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
at 65℃; Rate constant; sowie bei 75grad;

...Expand

: 100-68-5
methyl-phenyl-thioether

acetic acid anhydrideide: acetic acid anhydrideide

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 79 percent / potassium peroxymonosulfate / H2O; tetrahydrofuran; methanol / 15 h / 25 °C View Scheme

: 100-68-5
methyl-phenyl-thioether

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 82 percent / AlCl3 / CHCl3 / 1.5 h / 5 °C 2: 100 percent / MMPP / methanol; CH2Cl2 / 3 h / 20 °C View Scheme
Multi-step reaction with 2 steps 1: 90 percent / AlCl3 / CHCl3 / 0 - 5 °C 2: KMnO4, AcOH / H2O / 60 - 70 °C View Scheme
Multi-step reaction with 2 steps 1: aluminum (III) chloride / chloroform / 2 h / Cooling 2: dihydrogen peroxide; ammonium molybdate / water; methanol / 20 °C View Scheme

: 21382-98-9
p-cyanophenyl methyl sulfide

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 98.5 percent / tetrahydrofuran; diethyl ether / 1.) -78 deg C - RT, 2.) RT, 2.5 h 2: 91 percent / mCPBA / CH2Cl2 / Ambient temperature View Scheme

: 103-04-8
(phenylthio)acetic acid

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: AlCl3 / nitrobenzene; CS2 2: aq. H2O2, HCl 3: 160 - 180 °C View Scheme

: 17067-15-1
(4-acetyl-phenylsulfanyl)-acetic acid

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: aq. H2O2, HCl 2: 160 - 180 °C View Scheme

: 100118-64-7
1-diacetoxymethyl-4-methanesulfonyl-benzene

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: aq. H2SO4 / ethanol 2: diethyl ether View Scheme

: 3185-99-7
Methyl p-tolyl sulfone

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: CrO3, H2SO4 / acetic acid 2: aq. H2SO4 / ethanol 3: diethyl ether View Scheme

: sodium metabisulfite

: 60-00-4
ethylenediaminetetraacetic acid

: 1778-09-2
4-(Methylthio)acetophenone

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With oxone In water; acetone

...Expand

: 75-09-2
dichloromethane

: 1778-09-2
4-(Methylthio)acetophenone

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With sodium hydrogencarbonate; magnesium bis(monoperoxyphthalate) hexahydrate In methanol
With sodium hydrogencarbonate; magnesium bis(monoperoxyphthalate) hexahydrate In methanol
With sodium hydrogencarbonate; magnesium bis(monoperoxyphthalate) hexahydrate In methanol

: 1778-09-2
4-(Methylthio)acetophenone

A (4-methylsulfonyl)acetophenone: (4-methylsulfonyl)acetophenone

B: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With m-chloroperoxybenzoic acid In dichloromethane	A n/a B 11.91 g (91%)

: 98-86-2
acetophenone

: 10297-73-1
4-(methanesulfonyl)acetophenone

Conditions

Conditions	Yield
With m-chloroperoxybenzoic acid In dichloromethane; 4-(Methylthio)acetophenone	11.91 g (91%)

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 5123-13-7
5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane

: (-)-(R)-1-(4-(methylsulfonyl)phenyl)-1-phenylethan-1-ol

Conditions

Conditions	Yield
With hydrogenchloride; bis(1,5-cyclooctadiene)nickel (0); sodium methylate; C67H68N2 In cyclohexane; water at 50℃; for 1h; Inert atmosphere; enantioselective reaction;	99%

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 100-63-0
phenylhydrazine

: 203198-39-4
4-(methylsulfonyl)acetophenone phenylhydrazone

Conditions

Conditions	Yield
With acetic acid In ethanol at 70℃;	97%
In ethanol; acetic acid

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 50413-24-6
2-bromo-1-(4-methanesulfonylphenyl)ethanone

Conditions

Conditions	Yield
With bromine In chloroform at 34 - 36℃; for 0.25h; Solvent;	94.4%
With bromine; acetic acid at 20℃;	93%
With N-Bromosuccinimide; toluene-4-sulfonic acid In acetonitrile at 80℃;	89%

: 504-29-0
2-aminopyridine

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 1222-57-7
zolimidine

Conditions

Conditions	Yield
With tetrabutylammonium tetrafluoroborate; hydrogen iodide In ethanol at 50℃; for 24h; Electrochemical reaction; Schlenk technique; Green chemistry;	94%
With indium(III) triflate; copper(l) iodide; oxygen In 1-methyl-pyrrolidin-2-one at 100℃; under 760.051 Torr; for 30h; Schlenk technique;	90%
With iodine In ethanol at 20℃; for 3h; Green chemistry;	74%

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 25888-99-7
1-(4-(methylsulfonyl)phenyl)ethan-1-ol

Conditions

Conditions	Yield
With tris(pentafluorophenyl)borate; hydrogen In toluene at 60℃; under 45603.1 Torr; for 12h; Reagent/catalyst; Molecular sieve;	94%
With methanol; sodium tetrahydroborate In tetrahydrofuran at 0℃; for 2h;	87%
With water; 1,8-diazabicyclo[5.4.0]undec-7-ene; bis(pinacol)diborane at 60℃; for 10h; Sealed tube; chemoselective reaction;	80%
With sodium tetrahydroborate In methanol at 0 - 25℃;	68%
With methanol; sodium tetrahydroborate at 0 - 20℃; Inert atmosphere; Schlenk technique;

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 726192-01-4
(R)-1-(4-(methylsulfonyl)phenyl)ethan-1-ol

Conditions

Conditions	Yield
With C37H40MnN2O2P2(1+)*Br(1-); sodium t-butanolate In isopropyl alcohol at 50℃; for 3h; Inert atmosphere; Schlenk technique; enantioselective reaction;	93%
Stage #1: 4-(methanesulfonyl)acetophenone With (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole Stage #2: With dimethylsulfide borane complex

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 85976-24-5
α,α-dibromo-4-methanesulfonylacetophenone

Conditions

Conditions	Yield
With bromine In chloroform; water at 50 - 55℃; for 0.25h;	91.7%
With bromine; acetic acid
With bromine In acetic acid at 40℃;

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 4403-69-4
2-amino-1-benzylamine

: 2-(4-(methylsulfonyl)phenyl)quinoline

Conditions

Conditions	Yield
With copper(II) bis(trifluoromethanesulfonate); toluene-4-sulfonic acid In toluene at 100℃; for 36h; Schlenk technique; Sealed tube;	91%

: (4-bromophenyl)hydrazine hydrochloride salt

: 10297-73-1
4-(methanesulfonyl)acetophenone

: C15H15BrN2O2S

Conditions

Conditions	Yield
With acetic acid In ethanol at 70℃;	91%

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 100-63-0
phenylhydrazine

: 1167493-77-7
(1E)-1-{1-[4-(methylsulfonyl)phenyl]ethylidene}-2-phenylhyldrazine

Conditions

Conditions	Yield
With acetic acid In ethanol for 1h;	89%

: 19012-03-4
N-methyl-3-formylindole

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 3-(1-methyl-1H-indol-3-yl)-1-(4-(methylsulfonyl)phenyl)prop-2-en-1-one

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 20℃; for 10h; Claisen-Schmidt Condensation;	89%

: 110-91-8
morpholine

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 2-(4-methanesulfonylphenyl)-1-(morpholin-4-yl)ethanethione

Conditions

Conditions	Yield
With sulfur at 75℃; for 3h; Temperature;	88%
With toluene-4-sulfonic acid; sulfur for 3h; Willgerodt-Kindler reaction; Reflux;	60%

: 877-03-2
5-bromo-1H-indole-3-carboxaldehyde

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 3-(5-bromo-1H-indol-3-yl)-1-(4-(methylsulfonyl)phenyl)prop-2-en-1-one

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 20℃; for 10h; Claisen-Schmidt Condensation;	88%

: 2206-27-1
dimethylsulfoxide-d6

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 149-44-0
rongalite

: C20H15(2)H3O6S3

Conditions

Conditions	Yield
With copper(II) nitrate trihydrate; iodine at 100℃; for 8h;	88%

...Expand

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 1-(4-(methylsulfonyl)phenyl)ethanamine

Conditions

Conditions	Yield
With nickel(II) tetrafluoroborate hexahydrate; ammonia; hydrogen; bis(2-diphenylphosphinoethyl)phenylphosphine In 2,2,2-trifluoroethanol at 120℃; for 24h; chemoselective reaction;	88%
With ammonia; hydrogen In tetrahydrofuran at 120℃; for 20h;	82%
With ammonium hydroxide; hydrogen at 140℃; under 48754.9 Torr; for 20h;

: 504-29-0
2-aminopyridine

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 1576-35-8
toluene-4-sulfonic acid hydrazide

: 2-[4-(methylsulfonyl)phenyl]-3-(p-tolylthio)imidazo[1,2-a]-pyridine

Conditions

Conditions	Yield
With iodine; dimethyl sulfoxide; triphenylphosphine at 100℃; for 12h;	88%

...Expand

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 100-16-3
4-nitrophenylhydrazone

: C15H15N3O4S

Conditions

Conditions	Yield
With acetic acid In ethanol at 70℃;	88%

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 4-(aminosulfonyl)phenylhydrazine hydrochloride

: C15H17N3O4S2

Conditions

Conditions	Yield
With acetic acid In ethanol at 70℃;	88%

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 446-52-6
2-Fluorobenzaldehyde

: 1-[4-(methylsulfonyl)phenyl]-3-(2-fluorophenyl)prop-2-en-1-one

Conditions

Conditions	Yield
With sodium hydroxide In methanol; water at 20℃; for 12h; Claisen-Schmidt Condensation;	86%

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 149-44-0
rongalite

: 67-68-5
dimethyl sulfoxide

: (4-(methylsulfonyl)phenyl)(5-(4-(methylsulfonyl)phenyl)-4-(methylthio)furan-2-yl)methanone

Conditions

Conditions	Yield
With copper(II) nitrate trihydrate; iodine at 100℃; for 8h;	85%

...Expand

: 1445-45-0
Trimethyl orthoacetate

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 1-(1,1-dimethoxyethyl)-4-(methylsulfonyl)benzene

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In methanol at 60℃; for 4h;	85%

: 120-57-0
piperonal

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 1-[4-(methylsulfonyl)phenyl]-3-(3,4-methylendioxyphenyl)prop-2-en-1-one

Conditions

Conditions	Yield
With sodium hydroxide In methanol; water at 20℃; for 12h; Claisen-Schmidt Condensation;	85%

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 593-56-6
N-methoxylamine hydrochloride

: 1240388-89-9
1-(4-(methylsulfonyl)phenyl)ethanone-O-methyl oxime

Conditions

Conditions	Yield
With sodium acetate In ethanol; water for 2h; Reflux;	84%

: 1204-86-0
4-(4-morpholinyl)benzaldehyde

: 10297-73-1
4-(methanesulfonyl)acetophenone

: (E)-1-(4-(methylsulfonyl)phenyl)-3-(4-morpholinophenyl)prop-2-en-1-one

Conditions

Conditions	Yield
With sodium hydroxide In methanol; water at 20℃; Claisen-Schmidt Condensation;	84%

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 1208-03-3
4-(bis(2-chloroethyl)amino)benzaldehyde

: (E)-3-(4-(bis(2-chloroethyl)amino)phenyl)-1-(4-(methylsulfonyl)phenyl)prop-2-en-1-one

Conditions

Conditions	Yield
With sodium hydroxide In methanol; water at 20℃; Claisen-Schmidt Condensation;	84%

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 456-48-4
3-Fluorobenzaldehyde

: 1-[4-(methylsulfonyl)phenyl]-3-(3-fluorophenyl)prop-2-en-1-one

Conditions

Conditions	Yield
With sodium hydroxide In methanol; water at 20℃; for 12h; Claisen-Schmidt Condensation;	84%

4-Methylsulfonylacetophenone Chemical Properties

IUPAC Name: 1-(4-methylsulfonylphenyl)ethanone
Molecular Formula: C₉H₁₀O₃S
Molecular Weight: 198.24 g/mol
Canonical SMILES: S(c1ccc(cc1)C(=O)C)(=O)(=O)C
InChI: InChI=1/C9H10O3S/c1-7(10)8-3-5-9(6-4-8)13(2,11)12/h3-6H,1-2H3
Mol File: 10297-73-1.mol
EINECS: 233-672-0
Product Categories: Osteoarthritis and Rheumatoid Arthritis
XLogP3: 0.9
H-Bond Donor: 0
H-Bond Acceptor: 3
Rotatable Bond Count: 2
Tautomer Count: 2
Exact Mass: 198.035065
MonoIsotopic Mass: 198.035065
Topological Polar Surface Area: 51.2
Heavy Atom Count: 13
Complexity: 279
Index of Refraction: 1.521
Molar Refractivity: 49.56 cm³
Molar Volume: 162.7 cm³
Polarizability: 19.64×10^-24cm³
Surface Tension: 39 dyne/cm
Density: 1.218 g/cm³
Flash Point: 242 °C
Enthalpy of Vaporization: 63.42 kJ/mol
Boiling Point: 385.4 °C at 760 mmHg
Melting Point: 126-129 °C(lit.)
Vapour Pressure of 4-Methylsulphonylacetophenone (CAS NO.10297-73-1): 3.82E-06 mmHg at 25 °C

4-Methylsulfonylacetophenone Safety Profile

Hazard Codes: Xi
Safety Statements: 24/25
S24/25: Avoid contact with skin and eyes.
WGK Germany: 3
Hazard Note: Irritant
HazardClass of 4-Methylsulphonylacetophenone (CAS NO.10297-73-1): Irritant

4-Methylsulfonylacetophenone Specification

4-Methylsulphonylacetophenone (CAS NO.10297-73-1), its Synonyms are 1-(4-(Methylsulphonyl)phenyl)ethan-1-one ; P-methylsulphonylacetophenone ; 1-(4-(Methylsulfonyl)phenyl)ethanone ; 1-(4-Methylsulfonyl-phenyl)-ethanone ; 4'-(Methylsulphonyl)acetophenone ; 4-(Methylsulphonyl)acetophenone ; 4'-(Methylsulfonyl)acetophenone . It is white to slightly yellow cryst. powder or needles.

Product Name

4-Methylsulphonylacetophenone

Synthetic route

4-Methylsulfonylacetophenone Chemical Properties

4-Methylsulfonylacetophenone Safety Profile

4-Methylsulfonylacetophenone Specification

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