Product Name

  • Name

    7-Hydroxyquinolinone

  • EINECS 812-453-9
  • CAS No. 70500-72-0
  • Article Data24
  • CAS DataBase
  • Density 1.282g/cm3
  • Solubility
  • Melting Point 187-192°C
  • Formula C9H7 N O2
  • Boiling Point 403.7oC at 760 mmHg
  • Molecular Weight 161.16
  • Flash Point 198°C
  • Transport Information
  • Appearance Pale yellow powder
  • Safety
  • Risk Codes R22; R43
  • Molecular Structure Molecular Structure of 70500-72-0 (7-Hydroxyquinolinone)
  • Hazard Symbols Xn,Xi
  • Synonyms 7-Hydroxy-1H-quinolin-2-one;7-Hydroxy-2(1H)-quinolinone; 7-Hydroxycarbostyril
  • PSA 53.09000
  • LogP 1.23370

Synthetic route

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
With palladium 10% on activated carbon; water; oxygen; acetic acid at 110 - 116℃; for 18h; Reagent/catalyst; Temperature;94.2%
With palladium 10% on activated carbon In decalin at 180℃; for 8h;90.9%
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In tetrahydrofuran at 66℃; for 4h; Catalytic behavior; Concentration; Solvent; Temperature;89%
2-oxo-1,2-dihydroquinolin-7-yl-acetate
220364-99-8

2-oxo-1,2-dihydroquinolin-7-yl-acetate

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
With sodium hydroxide In water for 1.5h;90%
C18H20BNO6

C18H20BNO6

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
Stage #1: C18H20BNO6 With aluminum (III) chloride; tris(pentafluorophenyl)borate In 5,5-dimethyl-1,3-cyclohexadiene at 0 - 70℃; for 2h;
Stage #2: With dihydrogen peroxide; acetic acid In 5,5-dimethyl-1,3-cyclohexadiene at 0 - 20℃; for 2h;		82.2%
C17H18BNO5

C17H18BNO5

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
Stage #1: C17H18BNO5 With aluminum (III) chloride; tris(pentafluorophenyl)borate In toluene at 0 - 90℃; for 2h;
Stage #2: With dihydrogen peroxide; acetic acid In toluene at 0 - 20℃; for 2h;		81.3%
(2E)-N-(3-methoxyphenyl)-3-phenylacrylamide
127033-74-3

(2E)-N-(3-methoxyphenyl)-3-phenylacrylamide

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
With aluminium trichloride In chlorobenzene at 120℃; for 2h;70%
With aluminium trichloride In chlorobenzene70%
With aluminum (III) chloride In chlorobenzene at 0℃; for 8h; Reflux;67%
7-hydroxy-2H-chromen-2-one
93-35-6

7-hydroxy-2H-chromen-2-one

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
With acetic acid In acetic acid for 3h; Substitution; Heating;55%
N-(3-methoxyphenyl)cinnamamide
15116-41-3

N-(3-methoxyphenyl)cinnamamide

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
With aluminum (III) chloride In chlorobenzene at 0 - 120℃;53%
With aluminum (III) chloride at 120 - 180℃; for 2.08333h;43%
With aluminum (III) chloride at 120 - 180℃; for 2h;
m-Anisidine
536-90-3

m-Anisidine

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 95 percent
2: 70 percent / AlCl3 / chlorobenzene
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / water; acetone / 20 °C / Cooling with ice
2: aluminum (III) chloride / chlorobenzene / 0 - 120 °C
View Scheme
Multi-step reaction with 2 steps
1: pyridine / dichloromethane / 1 h / 5 - 20 °C
2: aluminum (III) chloride / 2.08 h / 120 - 180 °C
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / acetone; water / 0.5 h
2: aluminum (III) chloride / chlorobenzene / 120 °C / Cooling with ice
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / acetone; water / 0.5 h / 0 °C
2: aluminum (III) chloride / chlorobenzene / Reflux
View Scheme
7-hydroxyquinoline 1-oxide
93499-67-3

7-hydroxyquinoline 1-oxide

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 24 percent / 2 h / Heating
2: 90 percent / 1.0 N NaOH / H2O / 1.5 h
View Scheme
m-Anisidine
536-90-3

m-Anisidine

glycocoll-alkyl ester hydrochloride

glycocoll-alkyl ester hydrochloride

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 95 percent / aq. K2CO3 / acetone / 0.5 h / 0 °C
2: 70 percent / AlCl3 / chlorobenzene / 2 h / 120 °C
View Scheme
m-Hydroxyaniline
591-27-5

m-Hydroxyaniline

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
With pyridine; AlCl3 In dichloromethane; ethyl acetate
Multi-step reaction with 3 steps
1.1: sodium hydrogencarbonate / dichloromethane / 0.5 h / 20 °C / Inert atmosphere
1.2: 2 h / 20 °C / Inert atmosphere
2.1: aluminum (III) chloride / N,N-dimethyl acetamide / 4 h / 70 - 140 °C
3.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / tetrahydrofuran / 2 h / 20 - 50 °C / Inert atmosphere
3.2: 1 h / 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 3 steps
1: sodium hydrogencarbonate / ethyl acetate / 20 - 30 °C
2: aluminum (III) chloride / N,N-dimethyl acetamide / 130 - 140 °C
3: palladium 10% on activated carbon; water; acetic acid; oxygen / 18 h / 110 - 116 °C
View Scheme
3-chloro-N-(3-hydroxyphenyl)propanamide
50297-40-0

3-chloro-N-(3-hydroxyphenyl)propanamide

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: aluminum (III) chloride / N,N-dimethyl acetamide / 4 h / 70 - 140 °C
2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / tetrahydrofuran / 2 h / 20 - 50 °C / Inert atmosphere
2.2: 1 h / 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: aluminum (III) chloride / N,N-dimethyl acetamide / 130 - 140 °C
2: palladium 10% on activated carbon; water; acetic acid; oxygen / 18 h / 110 - 116 °C
View Scheme
3,4-dimethoxy-trans-cinnamic acid
14737-89-4

3,4-dimethoxy-trans-cinnamic acid

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: thionyl chloride / toluene / 4 h / 70 °C
2.1: triethylamine / tetrahydrofuran / 2 h / -5 - 20 °C
3.1: tris(pentafluorophenyl)borate; aluminum (III) chloride / toluene / 2 h / 0 - 90 °C
3.2: 2 h / 0 - 20 °C
View Scheme
(E)-3,4-dimethoxycinnamic chloride
39856-08-1, 141236-46-6

(E)-3,4-dimethoxycinnamic chloride

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: triethylamine / tetrahydrofuran / 2 h / -5 - 20 °C
2.1: tris(pentafluorophenyl)borate; aluminum (III) chloride / toluene / 2 h / 0 - 90 °C
2.2: 2 h / 0 - 20 °C
View Scheme
(E)-3,4,5-trimethoxy-cinnamic acid
20329-98-0, 20329-99-1, 90-50-6

(E)-3,4,5-trimethoxy-cinnamic acid

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: thionyl chloride / toluene / 4 h / 70 °C
2.1: pyridine / tetrahydrofuran / 2 h / -5 - 20 °C
3.1: tris(pentafluorophenyl)borate; aluminum (III) chloride / 5,5-dimethyl-1,3-cyclohexadiene / 2 h / 0 - 70 °C
3.2: 2 h / 0 - 20 °C
View Scheme
(E)-3-(3,4,5-trimethoxyphenyl)acryloyl chloride
10263-19-1, 89652-61-9

(E)-3-(3,4,5-trimethoxyphenyl)acryloyl chloride

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: pyridine / tetrahydrofuran / 2 h / -5 - 20 °C
2.1: tris(pentafluorophenyl)borate; aluminum (III) chloride / 5,5-dimethyl-1,3-cyclohexadiene / 2 h / 0 - 70 °C
2.2: 2 h / 0 - 20 °C
View Scheme
m-Anisidine
536-90-3

m-Anisidine

Cinnamoyl chloride
102-92-1

Cinnamoyl chloride

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
Stage #1: m-Anisidine; Cinnamoyl chloride In dichloromethane for 4h; Reflux;
Stage #2: With aluminum (III) chloride In chlorobenzene for 8h; Reflux;
7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

2-chloroquinoline-7-ol
375358-19-3

2-chloroquinoline-7-ol

Conditions
ConditionsYield
With trichlorophosphate In N,N-dimethyl-formamide at 70 - 75℃; Reagent/catalyst;94%
With thionyl chloride In N,N-dimethyl-formamide at 0 - 70℃; for 1h;80.9%
4-chlorobutyl bromide
6940-78-9

4-chlorobutyl bromide

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

7-(4-chlorobutoxy)quinoline-2(1H)-one

7-(4-chlorobutoxy)quinoline-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 40 - 50℃; for 5h;93.7%
With triethylamine In ethanol at 60 - 80℃; for 2h; Concentration; Solvent; Temperature; Reagent/catalyst;92.2%
With sodium hydroxide In ethanol for 5h; Reflux;88%
acetic anhydride
108-24-7

acetic anhydride

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

2-oxo-1,2-dihydroquinolin-7-yl-acetate
220364-99-8

2-oxo-1,2-dihydroquinolin-7-yl-acetate

Conditions
ConditionsYield
With indium(III) triflate at 0 - 30℃; for 1h;90%
7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

tert-butyl 4-bromobutylcarbamate
164365-88-2

tert-butyl 4-bromobutylcarbamate

tert-butyl (4-((2-oxo-1,2-dihydroquinolin-7-yl)oxy)butyl)carbamate

tert-butyl (4-((2-oxo-1,2-dihydroquinolin-7-yl)oxy)butyl)carbamate

Conditions
ConditionsYield
With potassium carbonate In water; N,N-dimethyl-formamide at 45 - 55℃;87.4%
1,4-dibromo-butane
110-52-1

1,4-dibromo-butane

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

7–(4-bromobutoxy)quinolin-2(1H)-one
203395-59-9

7–(4-bromobutoxy)quinolin-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In acetone at 20℃; for 3h; Reflux;86.5%
With potassium carbonate In water; N,N-dimethyl-formamide at 30 - 40℃; for 4h;82%
With potassium carbonate In acetone for 4h; Reflux;78%
7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Diphenylphosphine oxide
4559-70-0

Diphenylphosphine oxide

3-(diphenylphosphoryl)-7-hydroxyquinolin-2(1H)-one

3-(diphenylphosphoryl)-7-hydroxyquinolin-2(1H)-one

Conditions
ConditionsYield
With eosin; dibenzoyl peroxide In water; dimethyl sulfoxide at 20℃; for 24h; Inert atmosphere; Irradiation; regioselective reaction;86%
3,4-difluoronitrobenzene
369-34-6

3,4-difluoronitrobenzene

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

7-(2-fluoro-4-nitrophenoxy)quinolin-2(1H)-one

7-(2-fluoro-4-nitrophenoxy)quinolin-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;86%
1-bromo-4-aminobutane
33977-38-7

1-bromo-4-aminobutane

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

7-(4-aminobutoxy)quinolin-2(1H)-one

7-(4-aminobutoxy)quinolin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 4-bromo-1-aminobutane With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: 7-hydroxy-1H-quinolin-2-one With sodium iodide In N,N-dimethyl-formamide at 100℃; for 0.666667h; Temperature;		84.3%
tert-butyl 4-(4-chlorobutyl)piperazine-1-carboxylate

tert-butyl 4-(4-chlorobutyl)piperazine-1-carboxylate

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

tert-butyl 4-(4-((2-oxo-1,2-dihydroquinolin-7-yl)oxy)butyl)piperazine-1-carboxylate

tert-butyl 4-(4-((2-oxo-1,2-dihydroquinolin-7-yl)oxy)butyl)piperazine-1-carboxylate

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 80 - 90℃;84.1%
7-(4-chlorobutoxy)quinoline-2(1H)-one

7-(4-chlorobutoxy)quinoline-2(1H)-one

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

7-(4-(2-oxo-1,2-dihydroquinolin-7-oxy)butoxy)quinolin-2(1H)-one

7-(4-(2-oxo-1,2-dihydroquinolin-7-oxy)butoxy)quinolin-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 80 - 90℃; for 20h;83%
C16H21N2S(1+)*Br(1-)

C16H21N2S(1+)*Br(1-)

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

Brexpiprazole
913611-97-9

Brexpiprazole

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 130 - 135℃; Reagent/catalyst; Temperature;82%
4-Bromo-1-butanol
33036-62-3

4-Bromo-1-butanol

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

7-(4-hydroxybutoxy)quinoline-2-(1H)-one

7-(4-hydroxybutoxy)quinoline-2-(1H)-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 24h; Reflux;81%
With potassium carbonate In water; N,N-dimethyl-formamide at 40 - 50℃;81.4%
4-chlorobutanal dimethyl acetal
29882-07-3

4-chlorobutanal dimethyl acetal

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

7-(4,4-dimethoxybutoxy)quinolin-2(1H)-one

7-(4,4-dimethoxybutoxy)quinolin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 7-hydroxy-1H-quinolin-2-one With potassium carbonate In N,N-dimethyl-formamide at 25 - 35℃; for 0.5h;
Stage #2: 4-chlorobutanal dimethyl acetal In N,N-dimethyl-formamide at 70 - 75℃; for 10h;		80%
With tetrabutylammomium bromide; potassium carbonate In dimethyl sulfoxide at 20 - 70℃; for 20h;
4-Chloro-1-butanol
928-51-8

4-Chloro-1-butanol

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

7-(4-hydroxybutoxy)quinoline-2-(1H)-one

7-(4-hydroxybutoxy)quinoline-2-(1H)-one

Conditions
ConditionsYield
Stage #1: 7-hydroxy-1H-quinolin-2-one With potassium carbonate In N,N-dimethyl-formamide at 25 - 35℃; for 0.5h;
Stage #2: 4-Chloro-1-butanol In N,N-dimethyl-formamide at 70 - 75℃;		80%
7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

7–(3-bromopropoxy)quinolin-2(1H)-one
1076199-59-1

7–(3-bromopropoxy)quinolin-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In acetone for 4h; Reflux;79%
With potassium carbonate In ethanol Reflux;55%
With potassium carbonate In acetonitrile at 50℃; for 20h;
7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

2-bromoquinolin-7-ol

2-bromoquinolin-7-ol

Conditions
ConditionsYield
With phosphorus tribromide In N,N-dimethyl-formamide at 70 - 75℃;79%
Methyl 4-bromobutyrate
4897-84-1

Methyl 4-bromobutyrate

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

4-(2-Oxo-1,2-dihydro-quinolin-7-yloxy)-butyric acid methyl ester
87364-43-0

4-(2-Oxo-1,2-dihydro-quinolin-7-yloxy)-butyric acid methyl ester

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In isopropyl alcohol for 4h; Heating;78%
4-chloro-1,1-diethoxybutane
6139-83-9

4-chloro-1,1-diethoxybutane

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

7-(4,4-diethoxybutoxy)quinolin-2(1H)-one

7-(4,4-diethoxybutoxy)quinolin-2(1H)-one

Conditions
ConditionsYield
With tetrabutylammomium bromide; sodium carbonate In dimethyl sulfoxide at 100 - 110℃; for 3h; Reagent/catalyst; Solvent; Temperature; Large scale;78%
2,4-dichlorothieno[3,2-d]pyrimidine
16234-14-3

2,4-dichlorothieno[3,2-d]pyrimidine

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

7-(2-chlorothieno[3,2-d]pyrimidin-4-yloxy)quinolin-2(1H)-one

7-(2-chlorothieno[3,2-d]pyrimidin-4-yloxy)quinolin-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In water; acetonitrile at 70℃;78%
With potassium carbonate In water; acetonitrile Reflux;78%
C13H25N2O2(1+)*HO(1-)

C13H25N2O2(1+)*HO(1-)

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

tert-butyl 4-(4-((2-oxo-1,2-dihydroquinolin-7-yl)oxy)butyl)piperazine-1-carboxylate

tert-butyl 4-(4-((2-oxo-1,2-dihydroquinolin-7-yl)oxy)butyl)piperazine-1-carboxylate

Conditions
ConditionsYield
With N,N-dimethyl acetamide; potassium carbonate; 4-methyl-2-pentanone at 116 - 118℃; for 20h; Reagent/catalyst;77.9%
7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

ethylene dibromide
106-93-4

ethylene dibromide

7–(2-bromoethoxy)quinolin-2(1H)-one

7–(2-bromoethoxy)quinolin-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In acetone for 4h; Reflux;77%
With potassium hydroxide In methanol at 65℃; for 4h; Inert atmosphere;16.2%
1,5-dibromo-pentane
111-24-0

1,5-dibromo-pentane

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

7-((5-bromopentyl)oxy)quinolin-2(1H)-one

7-((5-bromopentyl)oxy)quinolin-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In acetone for 4h; Reflux;76%
With potassium carbonate In acetonitrile at 50℃; for 20h;
7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

2-bromo-4'-fluoroacetophenone
403-29-2

2-bromo-4'-fluoroacetophenone

7-<2-(4-fluorophenyl)-2-oxoethoxy>quinolin-2(1H)-one
220365-01-5

7-<2-(4-fluorophenyl)-2-oxoethoxy>quinolin-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 24.5h; Ambient temperature;75%
1-ethyl-2-methylquinolinium iodide
606-55-3

1-ethyl-2-methylquinolinium iodide

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

1-ethyl-2-(7-hydroxy-1H-quinolin-2-ylidenemethyl)-quinolinium; iodide

1-ethyl-2-(7-hydroxy-1H-quinolin-2-ylidenemethyl)-quinolinium; iodide

Conditions
ConditionsYield
With piperidine In ethanol Condensation; Heating;75%
7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

allyl bromide
106-95-6

allyl bromide

7-(prop-2-en-1-yloxy)-1,2-dihydroquinolin-2-one
177419-02-2

7-(prop-2-en-1-yloxy)-1,2-dihydroquinolin-2-one

Conditions
ConditionsYield
With potassium carbonate In acetone at 60℃; for 16h;74%
With potassium carbonate In acetone at 60℃; for 16h;74%
1 ,6-dibromohexane
629-03-8

1 ,6-dibromohexane

7-hydroxy-1H-quinolin-2-one
70500-72-0

7-hydroxy-1H-quinolin-2-one

7-((6-bromohexyl)oxy)quinolin-2(1H)-one

7-((6-bromohexyl)oxy)quinolin-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In acetone for 4h; Reflux;74%

7-Hydroxyquinolinone Chemical Properties

Molecular structure of 7-Hydroxyquinolinone (CAS NO.70500-72-0) is:

Product Name: 7-Hydroxyquinolinone
CAS Registry Number: 70500-72-0
Systematic Name: 7-hydroxyquinolin-2(1H)-one
Empirical Formula: C9H7NO2
Molecular Weight: 161.1574 
Melting Point: 187-192°C
Index of Refraction: 1.639
Molar Refractivity: 43.391 cm3
Molar Volume: 120.517 cm3
Surface Tension: 55.384 dyne/cm
Density: 1.337 g/cm3
Flash Point: 211.944 °C
Enthalpy of Vaporization: 70.809 kJ/mol
Boiling Point: 426.837 °C at 760 mmHg
Product Categories: Aromatics Compounds;Quinoline;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals

7-Hydroxyquinolinone Specification

 7-Hydroxyquinolinone , its cas register number is 70500-72-0. It also can be called 7-Hydroxy-2-(1H)-quinolinone ; 7-Hydroxycarbostyril ; 2,7-Dihydroxyquinoline ; 7-Hydroxy-2-Quinolinone ; 7-Hydroxy-1h-Quinolin-2-One ; 7-Hydroxyquinoline-(1h)-2-One ; 3,4-Dihydro-7-hydroxyquinoline-2(1H)-one .It is a off-white solid.

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