Product Name

  • Name

    Benzophenone

  • EINECS 204-337-6
  • CAS No. 119-61-9
  • Article Data3229
  • CAS DataBase
  • Density 1.11 g/cm3
  • Solubility insoluble (<0.1 g/100 mL at 25 °C)
  • Melting Point 47-51 °C(lit.)
  • Formula C13H10O
  • Boiling Point 305.4 °C at 760 mmHg
  • Molecular Weight 182.222
  • Flash Point 123.7 °C
  • Transport Information
  • Appearance Orange crystals
  • Safety 26-61-37/39-29-60-36-62-36/37-33-16-9
  • Risk Codes 36/37/38-52/53-50/53-67-65-62-51/53-48/20-11
  • Molecular Structure Molecular Structure of 119-61-9 (Benzophenone)
  • Hazard Symbols IrritantXi,DangerousN,FlammableF HarmfulXn
  • Synonyms Methanone, diphenyl-;alpha-Oxoditane;Kayacure BP;Benzene, benzoyl-;Diphenyl ketone;Ketone, diphenyl;Diphenylketone;alpha-oxodiphenylmethane;Diphenylmethanone;Phenyl ketone;Benzophenone Flakes;
  • PSA 17.07000
  • LogP 2.91760

Synthetic route

1,1-Diphenylethylene
530-48-3

1,1-Diphenylethylene

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
Stage #1: 1,1-Diphenylethylene for 0.05h; Inert atmosphere;
Stage #2: With tert.-butylhydroperoxide at 102℃; for 24h; Inert atmosphere;
100%
With oxygen at 110℃; for 8h; Temperature; Schlenk technique;99%
With oxygen at 110℃; for 8h; Temperature; Sealed tube;99%
1,1-Diphenylmethanol
91-01-0

1,1-Diphenylmethanol

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With acetone; zirconic acid In benzene at 80℃; for 8h;100%
With bis(2,2'-bipyridyl) copper(II) permanganate In dichloromethane for 0.5h; Ambient temperature;100%
With tert.-butylhydroperoxide; polystyrene-bound phenylselenic acid In tetrachloromethane for 24h; Heating;100%
Diphenylmethane
101-81-5

Diphenylmethane

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With potassium permanganate; iron(III) chloride In acetone at -78 - 20℃; for 16h;100%
With chromyl chloride In dichloromethane at 22℃; for 0.5h; ultrasound sonication;99%
With tert.-butylhydroperoxide; C45H52CuN4O3 In decane; acetonitrile at 70℃; for 18h;99%
Benzilic acid
76-93-7

Benzilic acid

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With pyridine chromium peroxide In dichloromethane for 0.3h; Product distribution; Ambient temperature; effect of various chromium(VI) based oxidants;100%
In acetic acid for 0.25h; Heating;100%
With sodium hydroxide; copper(III) periodate for 0.05h; Heating; oxidative decarboxylation of α-hydroxy acids; var. α-hydroxy acids, also Cu(III) tellurate as oxidant;95%
methanol
67-56-1

methanol

2,2-Dimethyl-4,4-diphenyl-3,3-bis(trimethylsilyl)-1-oxa-2-silacyclobutan
80431-43-2

2,2-Dimethyl-4,4-diphenyl-3,3-bis(trimethylsilyl)-1-oxa-2-silacyclobutan

A

benzophenone
119-61-9

benzophenone

B

1-(Dimethylmethoxysilyl)-1,1-bis(trimethylsilyl)ethan
68260-20-8

1-(Dimethylmethoxysilyl)-1,1-bis(trimethylsilyl)ethan

Conditions
ConditionsYield
In benzene at 110℃; for 40h; Rate constant; half live time;A n/a
B 100%
Benzophenone imine
1013-88-3

Benzophenone imine

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
Stage #1: Benzophenone imine With chloro-trimethyl-silane; sodium iodide In acetonitrile at 20℃;
Stage #2: With water In acetonitrile for 0.0833333h;
100%
With hydrogenchloride; water at 40℃;86%
With water at 25℃; Rate constant; effect of pH on the rate constants;
2,2-diphenyl-1,3-benzodithiole
61666-80-6

2,2-diphenyl-1,3-benzodithiole

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With tetrafluoroboric acid; mercury(II) oxide In tetrahydrofuran for 0.166667h; Ambient temperature;100%
2,2-diphenyl-1,3-oxathiolane
33735-40-9

2,2-diphenyl-1,3-oxathiolane

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With 2,2,2-trifluoroethanol; oxygen; vanadium(V) oxychloride for 5h; deprotection; Heating;100%
Stage #1: 2,2-diphenyl-1,3-oxathiolane In ethanol at 20℃;
Stage #2: With water In ethanol at 20℃;
98%
With silver(I) nitrite; iodine In tetrahydrofuran for 0.5h; Mechanism; Ambient temperature; other mono- and dithioacetals;96%
2,2-diphenyl-1,3-dithiolane
6317-10-8

2,2-diphenyl-1,3-dithiolane

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With K-10 clay supported iron(III) nitrate nonahydrate In dichloromethane for 3h; Ambient temperature; with K-10 clay-supported copper(II) nitrate trihydrate;100%
With trichloroisocyanuric acid; silver nitrate In water; acetonitrile Ambient temperature;100%
With hydrogenchloride; sodium nitrate In tetrachloromethane; water for 1h; Ambient temperature; other reagent;100%
diphenylmethyl trimethylsilyl ether
14629-59-5

diphenylmethyl trimethylsilyl ether

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With 2,6-dicarboxypyridinium fluorochromate In acetonitrile at 20℃; for 0.0833333h; Reflux;100%
With nitrogen dioxide at 20℃; for 0.5h;100%
With chromium(VI) oxide; tert.-butylhydroperoxide; triphenylhydroxysilane In dichloromethane for 24h; Ambient temperature;99%
2,2-diphenyl-1,3-dithiane
10359-08-7

2,2-diphenyl-1,3-dithiane

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With tetrafluoroboric acid; mercury(II) oxide In tetrahydrofuran Ambient temperature;100%
With dihydrogen peroxide; iodine; sodium dodecyl-sulfate In water at 20℃; for 0.333333h; Micellar solution;100%
With 2,4,4,6-Tetrabromo-2,5-cyclohexadien-1-one; dihydrogen peroxide In water; acetonitrile at 20℃; for 0.75h;100%
dimethoxydiphenylmethane
2235-01-0

dimethoxydiphenylmethane

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With water; Nafion-H In acetone for 0.5h;100%
With water; 2,3-dicyano-5,6-dichloro-p-benzoquinone In acetonitrile for 1h; Ambient temperature;100%
sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate In water at 30℃; for 0.5h;99%
tetraphenylethane-1,2-diol
464-72-2

tetraphenylethane-1,2-diol

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With N-Bromosuccinimide; triphenylbismuthane; potassium carbonate In water; acetonitrile for 2h; Ambient temperature;100%
With naphthalene-1,4-dicarbonitrile; oxygen for 90h; Irradiation;100%
With dinitrogen tetraoxide; ferric nitrate In ethyl acetate Heating; further oxidizing agent;100%
benzophenone-dibenzyldithioacetal
29055-89-8

benzophenone-dibenzyldithioacetal

A

dibenzyl disulphide
150-60-7

dibenzyl disulphide

B

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With hydrogenchloride; sodium nitrate In tetrachloromethane; water for 1h; Ambient temperature; other reagent;A n/a
B 100%
2-diphenylmethyliumyl-3,5-dioxo-4-phenyl-1,2,4-triazolidin-1-ide
2693-32-5

2-diphenylmethyliumyl-3,5-dioxo-4-phenyl-1,2,4-triazolidin-1-ide

A

benzophenone
119-61-9

benzophenone

B

4-Phenylurazole
15988-11-1

4-Phenylurazole

Conditions
ConditionsYield
With water for 1080h;A 100%
B 100%
With atmospheric moisture storage conditions;
(1R,5S)-4-Methyl-1,3,5,7,7-pentaphenyl-6-oxa-2,4-diaza-bicyclo[3.2.0]hept-2-ene
108099-97-4

(1R,5S)-4-Methyl-1,3,5,7,7-pentaphenyl-6-oxa-2,4-diaza-bicyclo[3.2.0]hept-2-ene

A

benzophenone
119-61-9

benzophenone

B

1-methyl-2,4,5-triphenyl-1H-imidazole
22397-44-0

1-methyl-2,4,5-triphenyl-1H-imidazole

Conditions
ConditionsYield
In various solvent(s) at 120℃; for 2.5h; Thermodynamic data; cycloreversion of further oxetane derivatives;A 100%
B 100%
benzoyl chloride
98-88-4

benzoyl chloride

C6H5Cu*ILi

C6H5Cu*ILi

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
In various solvent(s) -78 deg C, 0.5 h, 0 deg C, 0.5 h;100%
acetic acid
64-19-7

acetic acid

4,4a-dihydro-3,3-dimethyl-1-phenyl-4,4-bis(trimethylsilyl)-3H-2-oxa-3-silanaphthaline
80431-42-1

4,4a-dihydro-3,3-dimethyl-1-phenyl-4,4-bis(trimethylsilyl)-3H-2-oxa-3-silanaphthaline

A

benzophenone
119-61-9

benzophenone

B

Acetyldimethylsilyl-bis(trimethylsilyl)methan

Acetyldimethylsilyl-bis(trimethylsilyl)methan

Conditions
ConditionsYield
In benzene at 90℃; for 3h; Rate constant; half live time;A n/a
B 100%
2-diphenylmethylene-1,3-benzodithiole 1,1,3,3-tetraoxide
112520-04-4

2-diphenylmethylene-1,3-benzodithiole 1,1,3,3-tetraoxide

A

benzophenone
119-61-9

benzophenone

B

2H-benzo[d][1,3]dithiole 1,1,3,3-tetraoxide
112520-09-9

2H-benzo[d][1,3]dithiole 1,1,3,3-tetraoxide

Conditions
ConditionsYield
With potassium hydroxide In 1,4-dioxane for 0.5h; Product distribution; Heating; further educt: 2-diphenylmethylene-1,3-benzodithiole 1,1-dioxide;A 100%
B 88%
With potassium hydroxide In 1,4-dioxane for 0.5h; Heating; Yields of byproduct given;A n/a
B 88%
4,4a-dihydro-3,3-dimethyl-1-phenyl-4,4-bis(trimethylsilyl)-3H-2-oxa-3-silanaphthaline
80431-42-1

4,4a-dihydro-3,3-dimethyl-1-phenyl-4,4-bis(trimethylsilyl)-3H-2-oxa-3-silanaphthaline

tert-butyl alcohol
75-65-0

tert-butyl alcohol

A

benzophenone
119-61-9

benzophenone

B

tert-Butoxydimethylsilyl-bis(trimethylsilyl)methan
87161-31-7

tert-Butoxydimethylsilyl-bis(trimethylsilyl)methan

Conditions
ConditionsYield
In benzene at 90℃; for 1.5h; Rate constant; half live time;A n/a
B 100%
benzoyl chloride
98-88-4

benzoyl chloride

phenylmagnesium bromide
100-58-3

phenylmagnesium bromide

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride In tetrahydrofuran at 0℃;100%
Stage #1: benzoyl chloride With 1-methyl-pyrrolidin-2-one In toluene at 0℃; for 0.5h;
Stage #2: phenylmagnesium bromide In tetrahydrofuran; toluene at -10 - 0℃; for 4.25h; chemoselective reaction;
89%
In 2-methyltetrahydrofuran at 25℃; for 1h; Solvent; Concentration; Flow reactor; Green chemistry;85%
benzophenone azine
983-79-9

benzophenone azine

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With 2-phenyl-1,2-benzoisoselenazol-3(2H)-one; dihydrogen peroxide In methanol; water at 65℃; for 72h;100%
With ammonium cerium(IV) nitrate In water; acetonitrile at 50℃; for 16h; Oxidation;90%
With potassium permanganate; montmorillonite K-10 for 0.5h;90%
With 3-carboxypyridinium chlorochromate In acetonitrile for 3h; Heating;87%
diazodiphenylmethane
908093-98-1

diazodiphenylmethane

A

benzophenone
119-61-9

benzophenone

B

N2, N2O

N2, N2O

Conditions
ConditionsYield
With oxygen; methylene blue In benzene at 20℃; for 0.5h; Mechanism; Irradiation; N2/N2O ratio; var. solvent; other diazomethanes;A 100%
B n/a
benzylic acid

benzylic acid

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With tris paraperiodate In benzene for 1h; Heating;100%
2-Fluorobenzoyl chloride
393-52-2

2-Fluorobenzoyl chloride

1,4-dimethoxybezene
150-78-7

1,4-dimethoxybezene

A

benzophenone
119-61-9

benzophenone

B

2-methoxy-9H-xanthen-9-one
1214-20-6

2-methoxy-9H-xanthen-9-one

Conditions
ConditionsYield
With hydrogenchloride In AlCl3; 1,2-dichloro-ethaneA n/a
B 100%
N-cinnamyl-α,α-diphenyl-L-prolinol

N-cinnamyl-α,α-diphenyl-L-prolinol

A

benzophenone
119-61-9

benzophenone

B

C13H15NO

C13H15NO

Conditions
ConditionsYield
With sodium chlorite; sodium dihydrogenphosphate In tetrahydrofuran; water; tert-butyl alcohol diastereoselective reaction;A 100%
B 35%
[(hydrotris(3-phenyl-5-methylpyrazol-1-yl)borate)FeII(benzilate)]

[(hydrotris(3-phenyl-5-methylpyrazol-1-yl)borate)FeII(benzilate)]

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With oxygen In benzene for 0.75h;100%
1,1-Diphenylmethanol
91-01-0

1,1-Diphenylmethanol

diisopropyl-carbodiimide
693-13-0

diisopropyl-carbodiimide

A

benzophenone
119-61-9

benzophenone

B

N1,N2-Diisopropylformamidine
44843-38-1, 57585-44-1

N1,N2-Diisopropylformamidine

Conditions
ConditionsYield
With ruthenium complex In toluene at 120℃; for 24h; Inert atmosphere; Sealed tube;A 100%
B 74 %Spectr.
bis(ethylthio)diphenylmethane
7282-09-9

bis(ethylthio)diphenylmethane

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With K-10 clay supported copper(II) nitrate trihydrate In dichloromethane for 4h; Ambient temperature; with K-10 clay-supported iron(III) nitrate nonahydrate;99.5%
With K-10 clay supported copper(II) nitrate trihydrate In dichloromethane for 4h; Ambient temperature; K-10 clay supported iron(III) nitrate nonahydrate;99.5%
With dihydrogen peroxide; vanadia; ammonium bromide In dichloromethane; water at 0 - 5℃; for 2h;95%
Diphenylacetonitrile
86-29-3

Diphenylacetonitrile

benzophenone
119-61-9

benzophenone

Conditions
ConditionsYield
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride In toluene for 3h;99%
With tetrabutylammomium bromide; oxygen In N,N-dimethyl-formamide Hg cathode, Pt anode, -1.0 V vs SCE;95%
With oxygen; potassium carbonate In water; dimethyl sulfoxide Ambient temperature;95%
ethyl 2-bromoisobutyrate
600-00-0

ethyl 2-bromoisobutyrate

benzophenone
119-61-9

benzophenone

Ethyl 3-hydroxy-2,2-dimethyl-3,3-diphenylpropanoate
59697-75-5

Ethyl 3-hydroxy-2,2-dimethyl-3,3-diphenylpropanoate

Conditions
ConditionsYield
With iodine; zinc In 1,4-dioxane for 0.166667h; Reformatsky reaction; ultrasound irradiation;100%
With magnesium; benzene
With zinc; benzene
With zinc
benzophenone
119-61-9

benzophenone

phenylsilane
694-53-1

phenylsilane

bis-benzhydryloxy-phenyl-silane
18834-17-8

bis-benzhydryloxy-phenyl-silane

Conditions
ConditionsYield
With Et2OFe(catecholate-porous organic polymer) In benzene-d6 at 23℃; for 0.0833333h;100%
benzophenone
119-61-9

benzophenone

1,1-Diphenylmethanol
91-01-0

1,1-Diphenylmethanol

Conditions
ConditionsYield
With zinc(II) tetrahydroborate In acetonitrile for 16h; Mechanism; Ambient temperature;100%
With zinc(II) tetrahydroborate In acetonitrile for 16h; Ambient temperature;100%
With samarium; 1,2-Diiodoethane In 1,2-dimethoxyethane for 24h; Ambient temperature;100%
benzophenone
119-61-9

benzophenone

benzoic acid phenyl ester
93-99-2

benzoic acid phenyl ester

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; 3-chloro-benzenecarboperoxoic acid In dichloromethane for 6h; Ambient temperature;100%
With hydrogenchloride In chloroform at 20℃; for 8h; Baeyer-Villiger oxidation;100%
With dihydrogen peroxide; iodine; acetic acid at 20℃; for 0.166667h; Baeyer-Villiger oxidation;93%
benzophenone
119-61-9

benzophenone

Benzophenone oxime
574-66-3

Benzophenone oxime

Conditions
ConditionsYield
With hydroxylamine hydrochloride; sodium acetate In methanol Heating;100%
With hydroxylamine hydrochloride; sodium acetate In methanol; water Reflux;100%
With hydroxylamine hydrochloride In ethanol at 50 - 60℃; for 1.5h;100%
benzophenone
119-61-9

benzophenone

Diphenylmethane
101-81-5

Diphenylmethane

Conditions
ConditionsYield
With hydrogen; aluminum oxide; K5PV2Mo10O40 at 300℃; under 17480 Torr; for 3.33333h; Catalytic hydrogenation;100%
With iodine; hypophosphorous acid In acetic acid for 24h; Reduction; Heating;100%
With hydrogen In methanol at 20℃; under 760.051 Torr; for 10h; chemoselective reaction;100%
benzophenone
119-61-9

benzophenone

benzophenone hydrazone
5350-57-2

benzophenone hydrazone

Conditions
ConditionsYield
With hydrazine hydrate In ethanol for 12h; Heating;100%
With hydrazine hydrate; acetic acid In ethanol at 100℃; for 21h; Inert atmosphere;100%
With hydrazine hydrate In ethanol for 4h; Reflux;100%
benzophenone
119-61-9

benzophenone

1,1,2,2-tetraphenylethylene
632-51-9

1,1,2,2-tetraphenylethylene

Conditions
ConditionsYield
With woollins’ reagent In toluene for 20h; Heating;100%
With titanium tetrachloride; zinc In tetrahydrofuran at 0 - 70℃; for 12h; Inert atmosphere;98%
With pyridine; titanium tetrachloride; zinc In 1,4-dioxane for 0.0833333h; microwave irradiation;97%
benzophenone
119-61-9

benzophenone

tetraphenylethane-1,2-diol
464-72-2

tetraphenylethane-1,2-diol

Conditions
ConditionsYield
With hydrogen sulfide; phosphorous acid trimethyl ester In diethylene glycol dimethyl ether for 2.75h; Product distribution; Irradiation; variation of solvents, reagents and conditions;100%
With hydrogen sulfide; phosphorous acid trimethyl ester In diethylene glycol dimethyl ether for 2.75h; Irradiation;100%
With iodine; magnesium In diethyl ether; benzene for 0.5h; pinacol coupling; sonication;99%
benzophenone
119-61-9

benzophenone

ethane-1,2-dithiol
540-63-6

ethane-1,2-dithiol

2,2-diphenyl-1,3-dithiolane
6317-10-8

2,2-diphenyl-1,3-dithiolane

Conditions
ConditionsYield
Nafion-H In benzene Heating;100%
With cobalt(II) bromide In dichloromethane for 4h; Ambient temperature;99%
With amberlyst-15 In acetonitrile for 1h;99.91%
benzophenone
119-61-9

benzophenone

allyl bromide
106-95-6

allyl bromide

1,1-diphenyl-3-buten-1-ol
4165-79-1

1,1-diphenyl-3-buten-1-ol

Conditions
ConditionsYield
With ammonium acetate; zinc In tetrahydrofuran at 0℃; for 0.0166667h; Barbier reaction;100%
With manganese; chloro-trimethyl-silane; indium In tetrahydrofuran at 20℃; for 4h; Alkylation;98%
With manganese; chloro-trimethyl-silane; indium In tetrahydrofuran at 20℃; for 4h; Barbier allylation;98%
benzophenone
119-61-9

benzophenone

propargyl bromide
106-96-7

propargyl bromide

1,1-diphenyl-but-3-yn-1-ol
29430-66-8

1,1-diphenyl-but-3-yn-1-ol

Conditions
ConditionsYield
With zinc In tetrahydrofuran for 0.5h;100%
Stage #1: propargyl bromide With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In diethyl ether; hexane at -78℃; for 0.333333h;
Stage #2: benzophenone In diethyl ether at -78 - 20℃; for 2h;
Stage #3: With hydrogen cation In diethyl ether
96%
Stage #1: benzophenone; propargyl bromide With dysprosium; sodium iodide; mercury dichloride In tetrahydrofuran at -14 - 20℃; Propargylation;
Stage #2: With hydrogenchloride In water Hydrolysis;
92%
1,3-Benzothiazole
95-16-9

1,3-Benzothiazole

benzophenone
119-61-9

benzophenone

α,α-diphenyl-2-benzothiazolyl-methanol
120821-94-5

α,α-diphenyl-2-benzothiazolyl-methanol

Conditions
ConditionsYield
With t-Bu-P4 base In toluene at -78℃; for 1h;100%
Stage #1: 1,3-Benzothiazole; benzophenone With tetrakis{[tris(dimethylamino)phosphoranyliden]amino}phosphonium fluoride; tris(trimethylsilyl)amine In toluene at 25℃; for 24h; Inert atmosphere;
Stage #2: In tetrahydrofuran Reagent/catalyst;
94%
With n-butyllithium In tetrahydrofuran; hexane -78 deg C, 1 h; 10 min;88%
benzophenone
119-61-9

benzophenone

3-methoxyphenyl bromide
2398-37-0

3-methoxyphenyl bromide

(3-methoxyphenyl)(diphenyl)methanol
78238-98-9

(3-methoxyphenyl)(diphenyl)methanol

Conditions
ConditionsYield
Stage #1: 3-methoxyphenyl bromide With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: benzophenone In tetrahydrofuran; hexane at -78 - 20℃; Inert atmosphere;
100%
With magnesium 1.) ether, 2.) a) RT, 6 h, b) reflux, 1 h; Yield given. Multistep reaction;
With n-butyllithium
benzophenone
119-61-9

benzophenone

(Z)-ethyl cinnamate
4610-69-9

(Z)-ethyl cinnamate

(Z)-4-Hydroxy-3,4,4-triphenyl-but-2-enoic acid ethyl ester
78522-57-3

(Z)-4-Hydroxy-3,4,4-triphenyl-but-2-enoic acid ethyl ester

Conditions
ConditionsYield
With 2,2,6,6-tetramethyl-piperidine In tetrahydrofuran at -100℃; for 1.25h; Product distribution; other solvents, amount of reagents and different reaction times;100%
With 2,2,6,6-tetramethyl-piperidine In tetrahydrofuran at -100℃; for 1.25h;100%
benzophenone
119-61-9

benzophenone

trimethyl(2-methylenebut-3-enyl)silane
70901-64-3

trimethyl(2-methylenebut-3-enyl)silane

3-methylene-5,5-diphenyl-5-(trimethylsiloxy)pentene
86361-23-1

3-methylene-5,5-diphenyl-5-(trimethylsiloxy)pentene

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 50℃; for 2.5h;100%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 50℃; for 2.5h;100%
benzophenone
119-61-9

benzophenone

Methyltriphenylphosphonium bromide
1779-49-3

Methyltriphenylphosphonium bromide

1,1-Diphenylethylene
530-48-3

1,1-Diphenylethylene

Conditions
ConditionsYield
Stage #1: Methyltriphenylphosphonium bromide With n-butyllithium In tetrahydrofuran
Stage #2: benzophenone In tetrahydrofuran at 20℃; for 6h; Wittig reaction;
100%
Stage #1: Methyltriphenylphosphonium bromide With n-butyllithium In tetrahydrofuran at 0℃; for 1h; Inert atmosphere;
Stage #2: benzophenone In tetrahydrofuran at 20℃; Inert atmosphere;
94%
Stage #1: Methyltriphenylphosphonium bromide With potassium tert-butylate In diethyl ether at 20℃; for 0.25h; Inert atmosphere;
Stage #2: benzophenone In diethyl ether at 0℃; for 15h; Inert atmosphere;
87%
benzophenone
119-61-9

benzophenone

(dichloroalumino)(trichlorotitanio)methane
111317-20-5

(dichloroalumino)(trichlorotitanio)methane

1,1-Diphenylethylene
530-48-3

1,1-Diphenylethylene

Conditions
ConditionsYield
In toluene for 0.5h; Heating;100%

Benzophenone Chemical Properties

Molecular Structure of Benzophenone (CAS NO.119-61-9):

IUPAC Name: diphenylmethanone
Molecular formula C13H10O
Molar mass 182.217 g/mol
Melting point 47.9 °C
H bond acceptors: 1
H bond donors: 0
Freely Rotating Bonds: 2
Polar Surface Area: 17.07Å2
Index of Refraction: 1.583
Molar Refractivity: 56.04 cm3
Molar Volume: 167.5 cm3
Surface Tension: 42.1 dyne/cm
Density: 1.087 g/cm3
Flash Point: 123.7 °C
Melting point: 47-51 °C(lit.)
Enthalpy of Vaporization: 54.58 kJ/mol
Boiling Point: 305.4 °C at 760 mmHg
Vapour Pressure: 0.000823 mmHg at 25°C
InChI
InChI=1/C13H10O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H
Smiles
c1(C(c2ccccc2)=O)ccccc1
EINECS: 204-337-6
Water Solubility: insoluble (<0.1 g/100 mL at 25 ºC)
Merck: 14,1098
BRN: 1238185
Stability: Stable. Incompatible with strong oxidizing agents, strong reducing agents. Combustible
Product Categories: Pharmaceutical Intermediates; Additives for Plastic;Organics; Fluorescent Labels and Indicators; Analytical Chemistry; Environmental Endocrine Disruptors; Estradiol, etc. (Environmental Endocrine Disruptors); Functional Materials; Photopolymerization Initiators; Fluorescent Labels & Indicators

Benzophenone Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 727mg/kg (727mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
European Journal of Toxicology and Environmental Hygiene. Vol. 9, Pg. 99, 1976.
mouse LD50 oral 2895mg/kg (2895mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
European Journal of Toxicology and Environmental Hygiene. Vol. 9, Pg. 99, 1976.
rabbit LD50 skin 3535mg/kg (3535mg/kg)   Food and Cosmetics Toxicology. Vol. 11, Pg. 873, 1973.
rat LD50 oral > 10gm/kg (10000mg/kg)   Food and Cosmetics Toxicology. Vol. 11, Pg. 873, 1973.

Benzophenone Safety Profile

Hazard Codes: IrritantXi,DangerousN,HarmfulXn,FlammableF
Risk Statements: 36/37/38-52/53-50/53-67-65-62-51/53-48/20-11 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R67:Vapours may cause drowsiness and dizziness. 
R65:Harmful: may cause lung damage if swallowed. 
R62:Risk of impaired fertility. 
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R48/22:Harmful: danger of serious damage to health by prolonged exposure if swallowed. 
R11:Highly flammable.
Safety Statements: 26-61-37/39-29-60-36-62-36/37-33-16-9 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets. 
S37/39:Wear suitable gloves and eye/face protection. 
S29:Do not empty into drains. 
S60:This material and its container must be disposed of as hazardous waste. 
S36:Wear suitable protective clothing. 
S62:If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label. 
S36/37:Wear suitable protective clothing and gloves. 
S33:Take precautionary measures against static discharges. 
S16:Keep away from sources of ignition. 
S9:Keep container in a well-ventilated place.
RIDADR: UN 3077 9/PG 3
WGK Germany: 2
F: 10
HazardClass: 9

Benzophenone Specification

  Benzophenone , with CAS number of 119-61-9, can be called Benzene, benzoyl- ; Diphenylmethanone ; alpha-Oxodiphenylmethane ; alpha-Oxoditane ; Methanone, diphenyl- ; Ketone, diphenyl . It can be used as a photo initiator in UV-curing applications such as inks, imaging, and clear coatings in the printing industry.

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